Information on EC 3.4.21.B40 - kallikrein 9 and Organism(s) Homo sapiens and UniProt Accession Q9UKQ9

for references in articles please use BRENDA:EC3.4.21.B40
Word Map on EC 3.4.21.B40
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:
This record set is specific for:
Homo sapiens
UNIPROT: Q9UKQ9


The taxonomic range for the selected organisms is: Homo sapiens

The enzyme appears in selected viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.4.21.B40
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
kallikrein 9
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
CAS REGISTRY NUMBER
COMMENTARY hide
9001-01-8
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
polypeptide + H2O
peptides
show the reaction diagram
-
-
?
additional information
?
-
enzyme is regulated by steroid hormones in breast cancer cell line BT-474
-
-
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
polypeptide + H2O
peptides
show the reaction diagram
Q9UKQ9
-
-
?
additional information
?
-
Q9UKQ9
enzyme is regulated by steroid hormones in breast cancer cell line BT-474
-
-
-
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
low content
Manually annotated by BRENDA team
high content in adult, low content in fetal brain
Manually annotated by BRENDA team
low content
Manually annotated by BRENDA team
low content
Manually annotated by BRENDA team
low content
Manually annotated by BRENDA team
low content
Manually annotated by BRENDA team
low content
Manually annotated by BRENDA team
additional information
no enzyme expression in uterus, heart, adrenal gland, colon, spleen, skeletal muscle, pancreas, kidney, and fetal liver
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
45000
-
SDS-PAGE
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Ni-affinity chromatography to homogeneity
-
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
DNA sequence determination and analysis, gene is part of the human kallikrein multigene family, that mapps on chromosome 19q13.3-q13.4
His-tag fuision protein, expression in Escherichia coli BL21(DE3)
-