Disease on EC 3.4.21.B4 - granzyme K
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DISEASE 
TITLE OF PUBLICATION
LINK TO PUBMED
Aortic Aneurysm, Abdominal
Granzyme K - A novel marker to identify the presence and rupture of abdominal aortic aneurysm.
Arthritis
Inflammatory Gene Expression Profile and Defective Interferon-? and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients.
Arthritis, Juvenile
Inflammatory Gene Expression Profile and Defective Interferon-? and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients.
Asthma
Decrease of cytotoxic T cells in allergic asthma correlates with total serum immunglobulin E.
Colorectal Neoplasms
Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression.
Hepatitis C
Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries.
Hepatitis C
Yeast Endoplasmic Reticulum Sequestration Screening for the Engineering of Proteases from Libraries Expressed in Yeast.
Infections
Chlamydia trachomatis serovar L2 infection model using human lymphoid Jurkat cells.
Influenza, Human
Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB-/- mice.
Influenza, Human
Granzyme K inhibits replication of influenza virus through cleaving the nuclear transport complex importin ?1/? dimer of infected host cells.
Leukemia
Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia.
Lung Neoplasms
Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression.
Lymphoma
A natural killer cell granule protein that induces DNA fragmentation and apoptosis.
Melanoma
Proteomic analysis and the antimetastatic effect of N-(4-methyl)phenyl-O-(4-methoxy) phenyl-thionocarbamate-induced apoptosis in human melanoma SK-MEL-28 cells.
Multiple Sclerosis
Unexpected role for granzyme K in CD56bright NK cell-mediated immunoregulation of multiple sclerosis.
Neoplasms
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies.
Neoplasms
CD8-alpha T-cell infiltration in human papillomavirus-related oropharyngeal carcinoma correlates with improved patient prognosis.
Neoplasms
Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpesvirus Infection.
Neoplasms
Inflammatory Gene Expression Profile and Defective Interferon-? and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients.
Neoplasms
Valosin-containing protein cleavage by granzyme K accelerates an endoplasmic reticulum stress leading to caspase-independent cytotoxicity of target tumor cells.
Typhoid Fever
Expression of intra- and extracellular granzymes in patients with typhoid fever.
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