Disease on EC 3.4.21.B26 - proprotein convertase 5

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model.
Anorectal Malformations
Anorectal atresia and variants at predicted regulatory sites in candidate genes.
PCSK5 and GDF11 Expression in the Hindgut Region of Mouse Embryos with Anorectal Malformations.
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Spatiotemporal expression of proprotein convertase subtilisin/kexin type 5 in the development of anorectal malformations in fetal rats.
Anus, Imperforate
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Atherosclerosis
Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL.
Breast Neoplasms
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.
Carcinogenesis
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model.
Cardiovascular Diseases
Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels.
Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy.
Colonic Neoplasms
Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5.
Endometrial Neoplasms
Proprotein convertases in post-menopausal endometrial cancer: Distinctive regulation and non-invasive diagnosis.
Esophageal Atresia
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Infections
The role of furin in papillomavirus infection.
Nasal Polyps
Proprotein Convertase 5/6A is Associated with BMP-2-induced Squamous Cell Differentiation.
Neoplasm Metastasis
Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target.
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.
Neoplasms
Alterations in gene expression of proprotein convertases in human lung cancer have a limited number of scenarios.
Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5.
Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target.
Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth.
Proprotein convertases in post-menopausal endometrial cancer: Distinctive regulation and non-invasive diagnosis.
The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model.
Pheochromocytoma
PC5-A-mediated processing of pro-neurotensin in early compartments of the regulated secretory pathway of PC5-transfected PC12 cells.
Takayasu Arteritis
Genome-wide association study identifies susceptibility loci in IL6, RPS9/LILRB3, and an intergenic locus on chromosome 21q22 in Takayasu's arteritis.
Tracheoesophageal Fistula
Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.
Vaccinia
Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.
Processing of prothyrotropin-releasing hormone by the family of prohormone convertases.