Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Filter enzyme data
show all tables | show all data
hide all tables
No. of entries

Information on EC 3.4.21.91 - Flavivirin

for references in articles please use BRENDA:EC3.4.21.91

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

Known from classical flaviviruses (yellow fever, dengue fever). The functional viral peptidase is part of the NS2B protein. Catalytic His, Asp and Ser residues are arranged as in chymotrypsin, but flavivrin is the type example of peptidase family S7.

The enzyme appears in viruses and cellular organisms
Reaction Schemes
hide
Selective hydrolysis of -Xaa-Xaa-/-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala

Synonyms
ns3 protease, nonstructural protein 3, ns2b-ns3 protease, ns3 serine protease, ns2b-ns3pro, ns2b/ns3 protease, ns3 proteinase, ns3pro, ns2b/ns3, zikv protease, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Selective hydrolysis of -Xaa-Xaa-/-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala
show the reaction diagram
-
-
-
-
Highest Expressing Human Cell Lines
Cell Line Links Gene Links