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Disease on EC 3.4.21.85 - limulus clotting factor B

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Increased frequency of complement C4 'null' alleles in recurrent spontaneous abortions.
Tumour necrosis factor B gene polymorphism in relation to complotype in couples with spontaneous abortions and in control families.
Abscess
Complement activation in patients with amebic liver abscess.
[Complex MR-diagnosis of brain abscesses]
Acidosis
Complement and contact activation in term neonates after fetal acidosis.
Acquired Immunodeficiency Syndrome
[Immunologic laboratory tests in acquired immunodeficiency syndrome (AIDS) and suspected AIDS]
Acute Kidney Injury
Acute tubular necrosis is characterized by activation of the alternative pathway of complement.
Complement activation and toll-like receptor-2 signaling contribute to cytokine production after renal ischemia/reperfusion.
Evaluation of complement regulatory components in patients with atypical hemolytic uremic syndrome.
Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury.
Adenocarcinoma
Differential cytokine regulation of complement C3, C4, and factor B synthesis in human intestinal epithelial cell line, Caco-2.
Human prostate adenocarcinomas express in-vivo messenger-rnas and protein products for platelet-derived growth factor-B and its receptor.
Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma.
Adenoma
Detection of complement C3 and factor B gene expression in normal colorectal mucosa, adenomas and carcinomas.
Isolation of expressed sequence tags of skeletal muscle of neonatal healthy and splay leg piglets and mapping by somatic cell hybrid analysis.
Local complement genes expression in the mammary gland: effect of gestation and inflammation.
Adrenal Hyperplasia, Congenital
Defective, deleted or converted CYP21B gene and negative association with a rare restriction fragment length polymorphism allele of the factor B gene in congenital adrenal hyperplasia.
HLADR5 and C4BQO high frequency and antinuclear antibodies positivity in patients with 21 hydroxylase deficiency from Campania region.
Agammaglobulinemia
Complement activation in renal disease.
Safety and infectious prophylaxis of intravenous immunoglobulin in elderly patients with membranous nephropathy.
Albuminuria
Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy.
Alveolitis, Extrinsic Allergic
Levels of complement factors in human serum during immediate and late asthmatic reactions and during acute hypersensitivity pneumonitis.
Alzheimer Disease
Association cortex, cerebellum, and serum concentrations of C1q and factor B in Alzheimer's disease.
Anaphylaxis
Complement profiles in monkeys subjected to aggregate (immune complex) anaphylaxis, and following injection of soluble and particulate polysaccharides.
Anemia
Activation of the alternative pathway of human complement by haemoglobin.
Complement haemolytic activity, circulating immune complexes and the morbidity of sickle cell anaemia.
Deficiency of factor B of the complement system in sickle cell anaemia.
Immunological studies in sickle cell-beta zero thalassemia. Comparison with sickle cell anemia.
Anemia, Hemolytic
Evaluation of complement regulatory components in patients with atypical hemolytic uremic syndrome.
Anemia, Sickle Cell
Activation of the alternative pathway of human complement by haemoglobin.
Complement haemolytic activity, circulating immune complexes and the morbidity of sickle cell anaemia.
Defective yeast opsonisation and functional deficiency of complement in sickle cell disease.
Deficiency of factor B of the complement system in sickle cell anaemia.
Immunological studies in sickle cell-beta zero thalassemia. Comparison with sickle cell anemia.
Lack of evidence for altered complement and immunoglobulin levels in patients with sickle cell anaemia.
Plasma haemoglobin and complement activation in sickle cell disease.
Aneurysm
Expressions of PDGF-B and collagen type III in the remodeling of experimental saccular aneurysm in rats.
Aneurysm, Dissecting
Expression of platelet-derived growth factor B is upregulated in patients with thoracic aortic dissection.
Anti-Glomerular Basement Membrane Disease
Complement Activation Contributes to the Injury and Outcome of Kidney in Human Anti-glomerular Basement Membrane Disease.
The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease.
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
THE alternative complement pathway in ANCA-associated vasculitis: further evidence and a meta-analysis.
Antiphospholipid Syndrome
A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
Aortic Valve Stenosis
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis.
Arthritis
Activation of complement components C3 and factor B in synovial fluids.
Association of complement factor B allotypes and serum biomarkers in rheumatoid arthritis patients and their relatives.
Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis.
Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment.
Pathogenic complement activation in collagen antibody- induced arthritis in mice requires amplification by the alternative pathway.
Sigma factor B and RsbU are required for virulence in Staphylococcus aureus-induced arthritis and sepsis.
Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis.
Arthritis, Experimental
Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis.
Arthritis, Infectious
Deficiency of the Complement Component 3 but Not Factor B Aggravates Staphylococcus aureus Septic Arthritis in Mice.
Arthritis, Rheumatoid
Activation of complement components C3 and factor B in synovial fluids.
Activation of the complement and properdin systems in rheumatoid arthritis.
Alternative pathway complement activation in rheumatoid arthritis.
Association of complement alleles C4AQ0 and C4B5 with rheumatoid arthritis in Japanese patients.
Association of complement factor B allotypes and serum biomarkers in rheumatoid arthritis patients and their relatives.
Ba and Bb fragments of factor B activation: fragment production, biological activities, neoepitope expression and quantitation in clinical samples.
C3b inactivator in the rheumatic diseases. Measurement by radial immunodiffusion and by inhibition of formation of properdin pathway C3 convertase.
Complement biosynthesis in human synovial tissue.
Depressed synovial fluid levels of properdin and properdin factor B in patients with rheumatoid arthritis.
Metabolism of C4 and factor B in rheumatoid arthritis. Relation to rheumatoid factor.
Metabolism of factor B of serum complement in rheumatoid arthritis.
Synthesis of complement components (C3, C2, B and C1-inhibitor) and lysozyme by human monocytes and macrophages.
Asthma
[Complement fragments in patients with bronchial asthma]
Astrocytoma
[Application of flow cytometry to chemotherapy of malignant brain tumor]
Atherosclerosis
Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice.
Stimulation of Na-dependent phosphate transport by platelet-derived growth factor in rat aortic smooth muscle cells.
Atypical Hemolytic Uremic Syndrome
A complement factor B mutation in a large kindred with atypical hemolytic uremic syndrome.
A novel mutation in the complement factor B gene (CFB) and atypical hemolytic uremic syndrome.
Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach.
Atypical hemolytic uremic syndrome and acute tubular necrosis induced by complement factor B gene (CFB) mutation: A case report.
Atypical hemolytic uremic syndrome associated with a factor B genetic variant and fluid-phase complement activation: an exception to the rule?
Atypical hemolytic uremic syndrome in children: complement mutations and clinical characteristics.
Combination of a Novel Genetic Variant in CFB Gene and a Pathogenic Variant in COL4A5 Gene in a Sibling Renal Disease: A Case Report.
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report.
Diagnostic Utility of Complement Serology for Atypical Hemolytic Uremic Syndrome.
Evaluation of complement regulatory components in patients with atypical hemolytic uremic syndrome.
Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis.
Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.
Mutation of complement factor B causing massive fluid-phase dysregulation of the alternative complement pathway can result in atypical hemolytic uremic syndrome.
Mutations in proteins of the alternative pathway of complement and the pathogenesis of atypical hemolytic uremic syndrome.
Update on evaluating complement in hemolytic uremic syndrome.
[Complement factor B mutation in atypical hemolytic uremic syndrome. Rare cause of rare disease].
Autoimmune Diseases
Ba and Bb fragments of factor B activation: fragment production, biological activities, neoepitope expression and quantitation in clinical samples.
Azoospermia
A rare Y chromosome constitutional rearrangement: a partial AZFb deletion and duplication within chromosome Yp in an infertile man with severe oligoasthenoteratozoospermia.
Complete AZFb Deletion of Y Chromosome in an Infertile Male with Severe Oligoasthenozoospermia: Case Report and Literature Review.
Development of a multiplex quantitative fluorescent PCR assay for identification of rearrangements in the AZFb and AZFc regions.
Karyotypic abnormalities and molecular analysis of Y chromosome microdeletion in Iranian Azeri Turkish population infertile men.
Meiotic arrest at the midpachytene stage in a patient with complete azoospermia factor b deletion of the Y chromosome.
The human Y chromosome's azoospermia factor b (AZFb) region: sequence, structure, and deletion analysis in infertile men.
Y-chromosome microdeletion and its effect on reproductive decisions in taiwanese patients presenting with nonobstructive azoospermia.
Bacteremia
A comparison of immunologic profiles and their influence on bacteremia in surgical patients with a high risk of infection.
Activation of the properdin pathway of complement in patients with gram-negative of bacteremia.
Complement levels in pneumococcal pneumonia.
Magnitude of bacteremia and complement activation during Neisseria meningitidis infection: study of two co-primary cases with different clinical presentations.
Bacterial Infections
17Beta-estradiol affects the response of complement components and survival of rainbow trout (Oncorhynchus mykiss) challenged by bacterial infection.
Immunoglobulin deficiencies and susceptibility to infection among homozygotes and heterozygotes for C2 deficiency.
Blast Crisis
Transformation from atypical chronic myeloid leukemia to chronic myelomonocytic leukemia as progression of myeloid neoplasm with platelet-derived growth factor ß rearrangement.
Blindness
The role of complement in AMD.
Blister
Complement components in blood serum and suction blister fluid in erythropoietic protoporphyria.
Epidermolysis bullosa acquisita and inflammatory bowel disease.
Role of different pathways of the complement cascade in experimental bullous pemphigoid.
Bone Resorption
Antiresorptive activity of osteoprotegerin requires an intact heparan sulfate-binding site.
Correlation between platelet-derived growth factor B chain and bone resorption in rat periapical lesions.
Ligand-induced downregulation of receptors for TGF-beta in human osteoblast-like cells from adult donors.
Brain Death
Blocking Complement Factor B Activation Reduces Renal Injury and Inflammation in a Rat Brain Death Model.
Brain Diseases
Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure.
Brain Injuries, Traumatic
Elevated levels of the complement components C3 and factor B in ventricular cerebrospinal fluid of patients with traumatic brain injury.
Brain Neoplasms
Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence.
[Application of flow cytometry to chemotherapy of malignant brain tumor]
[Chemo-sensitivity test for malignant brain tumors by DNA histogram, in vitro]
Breast Neoplasms
Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study.
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells.
Bronchopneumonia
Complement activation in pneumonia.
Burkitt Lymphoma
Factor B of the alternative complement pathway on human lymphocytes.
Carcinoma
Clinicopathological significance of platelet-derived growth factor B, platelet-derived growth factor receptor-?, and E-cadherin expression in gastric carcinoma.
Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma.
Detection of complement C3 and factor B gene expression in normal colorectal mucosa, adenomas and carcinomas.
Expression of c-sis/platelet-derived growth factor B, insulin-like growth factor I, and transforming growth factor alpha messenger RNAs and their respective receptor messenger RNAs in primary human gastric carcinomas: in vivo studies with in situ hybridization and immunocytochemistry.
The Involvement of PDGF-B/PDGFR? Axis in the Resistance to Antiangiogenic and Antivascular Therapy in Renal Cancer.
Carcinoma, Hepatocellular
Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters.
Echo planar MR imaging of the liver: comparison of images with and without motion probing gradients.
Effect of conditioned media of acute myeloid leukemia blast cells on complement synthesis by cultured human cells of monocyte and hepatocyte origin.
Effect of interferon-gamma on complement gene expression in different cell types.
Hormonal regulation of complement biosynthesis in human cell lines--II. Upregulation of the biosynthesis of complement components C3, factor B and C1 inhibitor by interleukin-6 and interleukin-1 in human hepatoma cell line.
Human keratinocytes and A-431 cells synthesize and secrete factor B, the major zymogen protease of the alternative complement pathway.
Identification of differentially expressed proteins between human hepatoma and normal liver cell lines by two-dimensional electrophoresis and liquid chromatography-ion trap mass spectrometry.
Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma.
Interleukin-1-mediated enhancement of mouse factor B gene expression via NF kappa B-like hepatoma nuclear factor.
Regulation of class III major histocompatibility complex gene products by interleukin-1.
Carcinoma, Non-Small-Cell Lung
Vascular endothelial growth factor B coordinates metastasis of non-small cell lung cancer.
Carcinoma, Renal Cell
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
The Involvement of PDGF-B/PDGFR? Axis in the Resistance to Antiangiogenic and Antivascular Therapy in Renal Cancer.
The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma.
Carcinoma, Squamous Cell
Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma.
Human keratinocytes and A-431 cells synthesize and secrete factor B, the major zymogen protease of the alternative complement pathway.
Cardiomegaly
Redox-sensitive intermediates mediate angiotensin II-induced p38 MAP kinase activation, AP-1 binding activity, and TGF-beta expression in adult ventricular cardiomyocytes.
Cardiotoxicity
Resveratrol attenuates doxorubicin-induced cardiotoxicity in rats by up-regulation of vascular endothelial growth factor B.
Cholangiocarcinoma
Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma.
Choriocarcinoma
Successive activation of the platelet-derived growth factor beta receptor and platelet-derived growth factor B genes correlates with the genesis of human choriocarcinoma.
Choroidal Neovascularization
Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.
Complement factor B knockdown by short hairpin RNA inhibits laser-induced choroidal neovascularization in rats.
Local production of the alternative pathway component, Factor B, is sufficient to promote laser-induced choroidal neovascularization.
Chromosome Disorders
Karyotypic abnormalities and molecular analysis of Y chromosome microdeletion in Iranian Azeri Turkish population infertile men.
Chronic Urticaria
[Chronic urticaria and acquired complement deficiency due to a nephritic factor (C3NeF)]
Colitis
Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis.
Colitis, Ulcerative
Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease.
Colonic Neoplasms
C8orf4 is a transforming growth factor B induced transcript downregulated in metastatic colon cancer.
Colorectal Neoplasms
Bcl11A/CTIP1 mediates the effect of the glutamate receptor on axon branching and dendrite outgrowth.
Down-regulation of SAFB sustains the NF-?B pathway by targeting TAK1 during the progression of colorectal cancer.
Inhibition of Colorectal Cancer Cell Proliferation by Regulating Platelet-Derived Growth Factor B Signaling with a DNA Aptamer
The clinical implications of platelet derived growth factor B, vascular endothelial growth factor and basic fibroblast growth factor in colorectal cancer.
Connective Tissue Diseases
Autoantibody to scaffold attachment factor B (SAFB): A novel connective tissue disease-related autoantibody associated with interstitial lung disease.
COVID-19
Multi-organ complement deposition in COVID-19 patients.
Crohn Disease
C9 and factor B as acute phase proteins and their diagnostic and prognostic value in disease.
Enhanced local production of complement components in the small intestines of patients with Crohn's disease.
Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease.
Cross Infection
Molecular characterization of hospital-acquired methicillin-resistant Staphylococcus aureus strains in pediatric outbreaks using variable tandem repeat analysis with spa and ClfB typing.
Cryoglobulinemia
CD5 negative IGM rheumatoid factor B cells in B-chronic lymphocytic leukemia and benign mixed cryoglobulinemia.
Cytomegalovirus Infections
Complement components in kidney allograft recipients: relationship to cytomegalovirus infection.
Delirium
Diffuse CNS involvement in systemic lupus erythematosus: intrathecal synthesis of the 4th component of complement.
Demyelinating Diseases
Activation of complement pathways after contusion-induced spinal cord injury.
Laquinimod prevents cuprizone-induced demyelination independent of Toll-like receptor signaling.
The Alternative and Terminal Pathways of Complement Mediate Post-Traumatic Spinal Cord Inflammation and Injury.
The role of complement in immunological demyelination of the mammalian spinal cord.
Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Dengue
Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse.
Dermatitis, Atopic
Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis.
Complement and immunoglobulin deposits in the skin of patients with atopic dermatitis.
Dermatofibrosarcoma
Alternative PDGFD rearrangements in dermatofibrosarcomas protuberans without PDGFB fusions.
Dermatofibrosarcoma protuberans: a surgical disease with a molecular savior.
Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials.
Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans.
Diabetes Complications
VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content.
Diabetes Mellitus
Genetic polymorphism of factor B (Bf) and C3 component of complement in type 1 (insulin-dependent) diabetes mellitus: BFQO allele observed in a diabetic child.
HLA and complement allotypes in Type 1 (insulin-dependent) diabetes.
Plasma vascular endothelial growth factor B levels are increased in patients with newly diagnosed type 2 diabetes mellitus and associated with the first phase of glucose-stimulated insulin secretion function of ?-cell.
Diabetes Mellitus, Type 1
Age-related association of insulin-dependent diabetes mellitus with BfF1 and the HLA-B18, BfF1 haplotype.
Factor B (Bf) and glyoxalase genes in insulin-dependent diabetes mellitus.
HLA and complement allotypes in Type 1 (insulin-dependent) diabetes.
On the significance of C2, C4, and factor B polymorphisms in disease.
Diabetes Mellitus, Type 2
Plasma vascular endothelial growth factor B levels are increased in patients with newly diagnosed type 2 diabetes mellitus and associated with the first phase of glucose-stimulated insulin secretion function of ?-cell.
Diabetes, Gestational
Association of HLA-linked factor B with gestational diabetes mellitus in black women.
Diabetic Ketoacidosis
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report.
Digestive System Diseases
Profiles of serum complement in patients with hepatobiliary diseases.
Empyema
Loculated pleural empyema: identification of complement breakdown products in contiguous sterile pleural fluid.
[Activation of the alternative complement pathway in pleural fluid of patients with pneumonia]
Encephalomyelitis
Murine complement C4 is not required for experimental autoimmune encephalomyelitis.
Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Encephalomyelitis, Autoimmune, Experimental
Murine complement C4 is not required for experimental autoimmune encephalomyelitis.
Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Endocarditis
Contribution of clumping factor B to pathogenesis of experimental endocarditis due to Staphylococcus aureus.
Endometriosis
Deciphering biomarkers of endometriosis by proteomic analysis of eutopic endometrium in infertile patients.
Epidermolysis Bullosa Acquisita
Epidermolysis bullosa acquisita and inflammatory bowel disease.
Erythema Nodosum
Breakdown product of factor B as an index of complement activation in lepromatous leprosy and its relation with bacillary load.
Esophageal Neoplasms
Effects of Nutrition Intervention on Total and Cancer Mortality: 25-Year Post-trial Follow-up of the 5.25-Year Linxian Nutrition Intervention Trial.
Exanthema
Immunity to and infant mortality from measles.
Fatty Liver
Plasma vascular endothelial growth factor B is elevated in non-alcoholic fatty liver disease patients and associated with blood pressure and renal dysfunction.
Fibrosarcoma
Disodium Cromolyn and Anti-podoplanin Antibodies Strongly Inhibit Growth of BHK 21/C13-derived Fibrosarcoma in a Chick Embryo Chorioallantoic Membrane Model.
Gingival Overgrowth
Cyclosporine A upregulates platelet-derived growth factor B chain in hyperplastic human gingiva.
Glioblastoma
Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma.
Role of protein kinase C activation in synthesis of complement components C2 and factor B in interferon-gamma-stimulated human fibroblasts, glioblastoma cell line A172 and monocytes.
The role of transforming growth factor beta in glioma progression.
Glioma
A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models.
Expression of complement components of the alternative pathway by glioma cell lines.
Fluorine-labeled dasatinib nanoformulations as targeted molecular imaging probes in a PDGFB-driven murine glioblastoma model.
Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor ? and Yes Kinase.
Generation of diffuse intrinsic pontine glioma mouse models by brainstem-targeted in utero electroporation.
IDH1R132H is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment.
Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma.
Persistent roles of signal transduction of platelet-derived growth factor B in genesis, growth, and anaplastic transformation of gliomas in an in-vivo serial transplantation model.
Prognostic Value of CXCL12 Expression in 40 Low-Grade Oligodendrogliomas and Oligoastrocytomas.
Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence.
Tumor progression and oncogene addiction in a PDGF-B-induced model of gliomagenesis.
[Application of flow cytometry to chemotherapy of malignant brain tumor]
Glomerulonephritis
C3 glomerulonephritis associated with complement factor B mutation.
C3, C4, factor B and HLA-DR alpha mRNA expression in renal biopsy specimens from patients with IgA nephropathy.
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis.
Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.
Complement gene expression in hepatic and extrahepatic tissues of NZB and NZB x W (F1) mouse strains.
Correlations between serum factor B and C3b inactivator levels in normal subjects and in patients with infections, nephrosis and hypocomplementaemic glomerulonephritis.
Differential cytokine regulation of complement proteins in human glomerular epithelial cells.
Familial C3 glomerulonephritis associated with mutations in the gene for complement factor B.
Glomerulonephritis associated with deficiencies and polymorphisms of complement components encoded in the class III region of the MHC.
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Systemic complement activation in anti-neutrophil cytoplasmic antibody-associated vasculitis and necrotizing glomerulonephritis.
Glomerulonephritis, IGA
C3, C4, factor B and HLA-DR alpha mRNA expression in renal biopsy specimens from patients with IgA nephropathy.
C4 isotype deficiency in IgA nephropathy.
Factor B subtypes in Japanese patients with IgA nephropathy and with idiopathic membranous nephropathy.
Genetic study on HLA class II and class III region in the disease associated with IgA nephropathy.
Role for specific complement phenotypes and deficiencies in the clinical expression of IgA nephropathy.
Glomerulonephritis, Membranoproliferative
Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach.
Classical complement pathway activation in membranoproliferative glomerulonephritis.
Combined C3b and factor B autoantibodies and MPGN type II.
Control of serum C3 levels by beta 1H and C3b inactivator.
Correlations between serum factor B and C3b inactivator levels in normal subjects and in patients with infections, nephrosis and hypocomplementaemic glomerulonephritis.
Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis.
Glomerular deposition of complement-control proteins in acute and chronic glomerulonephritis.
Human anti-idiotypic antibody responses to autoantibody against the alternative pathway C3 convertase.
Loss of autoantibody activity by alteration in autoantigen.
Patterns of complement activation in idiopathic membranoproliferative glomerulonephritis, types I, II, and III.
Renal transplantation for patients with type I and type II membranoproliferative glomerulonephritis: serial complement and nephritic factor measurements and the problem of recurrence of disease.
[Studies of complement, nephritic factor, and circulating immune complexes in chronic mesangiocapillary glomerulonephritis types I and II (author's transl)]
Glomerulonephritis, Membranous
Factor B subtypes in Japanese patients with IgA nephropathy and with idiopathic membranous nephropathy.
On the significance of C2, C4, and factor B polymorphisms in disease.
Glomerulosclerosis, Focal Segmental
The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
Granulomatosis with Polyangiitis
Complement profile in microscopic polyangiitis and granulomatosis with polyangiitis: analysis using sera from a nationwide prospective cohort study.
Gynecomastia
Local complement genes expression in the mammary gland: effect of gestation and inflammation.
Heart Diseases
Involvement of the nuclear factor Kappa B (NF-?B) signaling pathway in regulation of cardiac G protein-coupled receptor kinase-5 (GRK5) expression.
Heart Failure
Vascular Endothelial Growth Factor B and Its Signaling.
HELLP Syndrome
The genetics of the alternative pathway of complement in the pathogenesis of HELLP syndrome.
Hemangioma
Echo planar MR imaging of the liver: comparison of images with and without motion probing gradients.
Hemoglobinuria
Complement research in the 18th-21st centuries: Progress comes with new technology.
Hemoglobinuria, Paroxysmal
Complement research in the 18th-21st centuries: Progress comes with new technology.
Hemolytic-Uremic Syndrome
Breakdown products of C3 and factor B in hemolytic-uremic syndrome.
Hemophilia B
Deuterohemophilia: plasma thromboplastin factor B deficiency: plasma thromboplastin component (PTC) deficiency, Christmas disease, hemophilia B.
Hepatitis
Elevated IgG and decreased complement component C3 and factor B in B-thalassaemia major.
Profiles of serum complement in patients with hepatobiliary diseases.
Hepatitis A
Zinc-sensitive genes as potential new target genes of the metal transcription factor-1 (MTF-1).
Hepatitis B
[Immunologic laboratory tests in acquired immunodeficiency syndrome (AIDS) and suspected AIDS]
Hepatitis B, Chronic
A missense variant in complement factor B (CFB) is a potential predictor of 24-week off-treatment response to PegIFN? therapy in Chinese HBeAg-positive chronic hepatitis B patients.
A non-synonymous variant rs12614 of complement factor B associated with risk of chronic hepatitis B in a Korean population.
Hepatitis C
Lymphomas complicating Sjögren's syndrome and hepatitis C virus infection may share a common pathogenesis: chronic stimulation of rheumatoid factor B cells.
Hepatitis, Alcoholic
Lack of plasma complement activation in severe acute alcoholic hepatitis.
Hepatitis, Chronic
Profiles of serum complement in patients with hepatobiliary diseases.
Hepatolenticular Degeneration
Profiles of serum complement in patients with hepatobiliary diseases.
Hereditary Complement Deficiency Diseases
Complement analysis in adult patients with a history of bacteremic pneumococcal infections or recurrent pneumonia.
Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice.
Murine complement deficiency ameliorates acute cigarette smoke-induced nasal damage.
Herpes Simplex
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.
Hyperlipidemias
Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice.
Hypersensitivity
[Immunologic laboratory tests in acquired immunodeficiency syndrome (AIDS) and suspected AIDS]
Hypersensitivity, Delayed
Immunoregulation by alpha 1 antitrypsin.
The alternative complement component factor B regulates UV-induced oedema, systemic suppression of contact and delayed hypersensitivity, and mast cell infiltration into the skin.
Hypotension
Complement profiles in monkeys subjected to aggregate (immune complex) anaphylaxis, and following injection of soluble and particulate polysaccharides.
Idiopathic Pulmonary Fibrosis
Pharmacological modulation of platelet-derived growth factor (B) mRNA expression in alveolar macrophages and adherent monocytes.
IgA Deficiency
C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes.
Immune Complex Diseases
Complement gene expression in hepatic and extrahepatic tissues of NZB and NZB x W (F1) mouse strains.
Immunoglobulin G4-Related Disease
B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease.
Infarction, Middle Cerebral Artery
The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
Infections
A murine model for the study of mycotic mastitis.
Activation of the alternative complement pathway in ascitic fluid during spontaneous bacterial peritonitis.
Allergic environment enhances airway epithelial pro-inflammatory responses to rhinovirus infection.
Alternative Sigma Factor B in Bovine Mastitis-Causing Staphylococcus aureus: Characterization of Its Role in Biofilm Formation, Resistance to Hydrogen Peroxide Stress, Regulon Members.
Antibody-independent, complement-mediated enhancement of HIV-1 infection by mannosidase I and II inhibitors.
Assessment of serum factor B, serum opsonins, granulocyte chemotaxis, and infection in nephrotic syndrome of children.
Bacterial and fungal infection in children with fulminant hepatic failure: possible role of opsonisation and complement deficiency.
C3, factor B, alpha-1-antitrypsin in neonatal septicaemia with sclerema.
Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target.
Complement changes in falciparum malaria infection.
Complement components in kidney allograft recipients: relationship to cytomegalovirus infection.
Contribution of clumping factor B to pathogenesis of experimental endocarditis due to Staphylococcus aureus.
Correlations between serum factor B and C3b inactivator levels in normal subjects and in patients with infections, nephrosis and hypocomplementaemic glomerulonephritis.
Differential effects of cytomegalovirus infection on complement synthesis by human mesangial cells.
Elevated IgG and decreased complement component C3 and factor B in B-thalassaemia major.
Equid herpesvirus 1: platelets and alveolar macrophages are potential sources of activated TGF-B1 in the horse.
Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.
Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency.
Human complement C9 and factor B in the diagnosis of infections in infants.
Human complement component factor B rescues HIV-1-infected leukemic T cells from cytopathic death.
Immunoglobulin deficiencies and susceptibility to infection among homozygotes and heterozygotes for C2 deficiency.
Increased liver protein and mRNA expression of natural killer cell-enhancing factor B (NKEF-B) in ayu (Plecoglossus altivelis) after Aeromonas hydrophila infection.
Increased susceptibility of complement factor B/C2 double knockout mice and mannan-binding lectin knockout mice to systemic infection with Candida albicans.
Molecular characterization, expression and antimicrobial activity of complement factor D in Megalobrama amblycephala.
Plasma levels of proteins of the alternative complement pathway in inbred mice that differ in resistance to Trypanosoma congolense infections.
Postoperative infections and variations of complement components in cancer patients.
Safety and infectious prophylaxis of intravenous immunoglobulin in elderly patients with membranous nephropathy.
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Scaffold attachment factor B suppresses HIV-1 infection of CD4+ T cells by preventing binding of RNA polymerase II to HIV-1's long terminal repeat.
Sepsis score and acute-phase protein response as predictors of outcome in septic surgical patients.
The acute phase response in Sicilian patients with boutonneuse fever admitted to hospitals in Palermo, 1992-1997.
The alternative pathway of complement in sheep during the course of infection with Trypanosoma congolense and after Berenil treatment.
The alternative sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host.
The role of complement in innate, adaptive and eosinophil-dependent immunity to the nematode Nippostrongylus brasiliensis.
The use of eculizumab in Capnocytophaga canimorsus associated thrombotic microangiopathy: a case report.
Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis.
Ubiquitin-specific protease 14 regulates LPS-induced inflammation by increasing ERK1/2 phosphorylation and NF-?B activation.
Infertility
Deciphering biomarkers of endometriosis by proteomic analysis of eutopic endometrium in infertile patients.
Inflammatory Bowel Diseases
Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease.
Insulin Resistance
A new effector of lipid metabolism: Complement factor properdin.
Adipose tissue complement factor B promotes adipocyte maturation.
Complement C3 and C-reactive protein are elevated in South Asians independent of a family history of stroke.
Complement Factor H is expressed in adipose tissue in association with insulin resistance.
Plasma vascular endothelial growth factor B is elevated in non-alcoholic fatty liver disease patients and associated with blood pressure and renal dysfunction.
Serum vascular endothelial growth factor B is elevated in women with polycystic ovary syndrome and can be decreased with metformin treatment.
Insulinoma
Essential role of glucokinase in the protection of pancreatic ? cells to the glucose energetic status.
Intracranial Thrombosis
A new complement factor B variant (BF S075) in Japanese.
Ischemic Stroke
Complement C3 and C-reactive protein are elevated in South Asians independent of a family history of stroke.
Selection of the optimum b factor for diffusion-weighted magnetic resonance imaging assessment of ischemic stroke.
[Complement componenets, C3 and factors B, in the blood of patients with acute ischemic stroke]
Joint Diseases
Aseptic arthritis in a man with toxic shock syndrome.
Depressed synovial fluid levels of properdin and properdin factor B in patients with rheumatoid arthritis.
Kidney Diseases
Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis.
Kidney Diseases, Cystic
The C-terminal tail of polycystin-1 regulates complement factor B expression by Signal Transducer and Activator of Transcription 1.
Kidney Failure, Chronic
Genetic regulation of the impaired immune response to hepatitis-B vaccine associated with low TCR density in end stage renal disease patients: contribution of complement C4 and factor B alleles.
Leiomyomatosis
Morphologic, Molecular, and Taxonomic Evolution of Renal Cell Carcinoma: A Conceptual Perspective With Emphasis on Updates to the 2016 World Health Organization Classification.
Leprosy, Lepromatous
Breakdown product of factor B as an index of complement activation in lepromatous leprosy and its relation with bacillary load.
Leukemia
A new apoptotic pathway for the complement factor B-derived fragment Bb.
Alignment of U3 region sequences of mammalian type C viruses: identification of highly conserved motifs and implications for enhancer design.
Altered gene expression in human cleidocranial dysplasia dental pulp cells.
C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma.
Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity.
Perturbation of autocrine/paracrine loops of burst-forming units of erythroid-derived cells in rHuEPO-hyporesponsive hemodialysis patients.
Point mutations in the Moloney murine leukemia virus enhancer identify a lymphoid-specific viral core motif and 1,3-phorbol myristate acetate-inducible element.
Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.
Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia.
Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes.
Therapeutic use of growth factors in the musculoskeletal system in sports-related injuries.
Two factors that bind to highly conserved sequences in mammalian type C retroviral enhancers.
Leukemia, Lymphocytic, Chronic, B-Cell
Autocrine expression of platelet-derived growth factor B in B cell chronic lymphocytic leukemia.
Leukemia, Lymphoid
CD5 negative IGM rheumatoid factor B cells in B-chronic lymphocytic leukemia and benign mixed cryoglobulinemia.
Leukemia, Myeloid, Acute
Effect of conditioned media of acute myeloid leukemia blast cells on complement synthesis by cultured human cells of monocyte and hepatocyte origin.
Leukemia, Myelomonocytic, Chronic
Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia.
Leukoencephalopathies
Detection of complement factor B in the cerebrospinal fluid of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy disease using two-dimensional gel electrophoresis and mass spectrometry.
limulus clotting factor b deficiency
A Novel Case of Complement Factor B Deficiency.
A previously unrecognized role of C3a in proteinuric progressive nephropathy.
Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression.
Deuterohemophilia: plasma thromboplastin factor B deficiency: plasma thromboplastin component (PTC) deficiency, Christmas disease, hemophilia B.
Genetic deficiencies of the complement system and association with disease--early components.
Mice deficient for the complement factor B develop and reproduce normally.
Murine complement deficiency ameliorates acute cigarette smoke-induced nasal damage.
Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus.
Shiga Toxin Promotes Podocyte Injury in Experimental Hemolytic Uremic Syndrome via Activation of the Alternative Pathway of Complement.
The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
Liver Abscess, Amebic
Amoebic liver abscess: serum immunoglobulins and complement in Northern Nigerian patients.
Liver Cirrhosis, Biliary
Profiles of serum complement in patients with hepatobiliary diseases.
Liver Diseases
Plasma vascular endothelial growth factor B is elevated in non-alcoholic fatty liver disease patients and associated with blood pressure and renal dysfunction.
Liver Diseases, Alcoholic
Profiles of serum complement in patients with hepatobiliary diseases.
Liver Neoplasms
Chemoprevention of primary liver cancer: a randomized, double-blind trial in Linxian, China.
Transcriptomic characterization reveals prognostic molecular signatures of sorafenib resistance in hepatocellular carcinoma.
Lung Diseases, Interstitial
A histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B gene.
Application of Proteomics in Sarcoidosis.
Autoantibody to scaffold attachment factor B (SAFB): A novel connective tissue disease-related autoantibody associated with interstitial lung disease.
Lung Neoplasms
Vascular endothelial growth factor B coordinates metastasis of non-small cell lung cancer.
[Experimental study of effects of retinoic acid on IL-1? and IFN-? induced C3 and factor B secretion in lung cancer cell line.]
Lupus Erythematosus, Systemic
Alternative complement pathway in hypocomplementemic/normal C1s-C1 inhibitor complex patients with SLE.
Ba and Bb fragments of factor B activation: fragment production, biological activities, neoepitope expression and quantitation in clinical samples.
C3b inactivator in the rheumatic diseases. Measurement by radial immunodiffusion and by inhibition of formation of properdin pathway C3 convertase.
Differential cytokine regulation of complement proteins in human glomerular epithelial cells.
Evaluation of alternative pathway and factor B haemolytic activities in patients with systemic lupus erythematosus: correlations with the alternative pathway regulatory proteins.
Factor B activation in systemic lupus erythematosus.
Factor B activation products in patients with systemic lupus erythematosus. A marker of severe disease activity.
Family study of systemic lupus erythematosus: analysis of the clinical history, skin immunofluorescence, and serologic parameters.
Measurement of complement components in systemic lupus erythematosus by radial immunodiffusion.
Participation of factor B in residual immune complex red cell binding activity observed in serum from a C2-deficient systemic lupus erythematosus patient may delay the appearance of clinical symptoms.
Regulation of plasma complement C4 and factor b levels in murine systemic lupus erythematosus.
Relationship between C4 null genes, HLA-D region antigens, and genetic susceptibility to systemic lupus erythematosus in Caucasian and black Americans.
Relative importance of C3b inactivator and beta 1H globulin in the modulation of the properdin amplification loop in systemic lupus erythematosus.
Specific inhibitor of complement (C5)-derived chemotactic activity in systemic lupus erythematosus related antigenically to the Bb fragment of human factor B.
UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE.
Lupus Nephritis
Activation of the alternative complement pathway in systemic lupus erythematosus.
Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation.
Complement gene expression in hepatic and extrahepatic tissues of NZB and NZB x W (F1) mouse strains.
Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice.
Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis.
Usefulness of complement split product, Bb, as a clinical marker for disease activity of lupus nephritis.
Lymphatic Metastasis
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells.
Lymphoma
Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.
B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.
B-Cell Lymphoma 6 (BCL6) Is a Host Restriction Factor That Can Suppress HBV Gene Expression and Modulate Immune Responses.
Bcl11A/CTIP1 mediates the effect of the glutamate receptor on axon branching and dendrite outgrowth.
Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation.
Essential role of glucokinase in the protection of pancreatic ? cells to the glucose energetic status.
Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models.
IL-6 Impairs Vaccine Responses in Neonatal Mice.
Improved cellular thermotolerance in cloned Holstein cattle derived with cytoplasts from a thermotolerant breed.
Lymphomas complicating Sjögren's syndrome and hepatitis C virus infection may share a common pathogenesis: chronic stimulation of rheumatoid factor B cells.
Mammary stem cells, self-renewal pathways, and carcinogenesis.
Morphologic, Molecular, and Taxonomic Evolution of Renal Cell Carcinoma: A Conceptual Perspective With Emphasis on Updates to the 2016 World Health Organization Classification.
Salivary gland lymphomas in patients with Sjögren's syndrome may frequently develop from rheumatoid factor B cells.
UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE.
Lymphoma, B-Cell
Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.
B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.
B-Cell Lymphoma 6 (BCL6) Is a Host Restriction Factor That Can Suppress HBV Gene Expression and Modulate Immune Responses.
Bcl11A/CTIP1 mediates the effect of the glutamate receptor on axon branching and dendrite outgrowth.
Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation.
Essential role of glucokinase in the protection of pancreatic ? cells to the glucose energetic status.
Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models.
IL-6 Impairs Vaccine Responses in Neonatal Mice.
Improved cellular thermotolerance in cloned Holstein cattle derived with cytoplasts from a thermotolerant breed.
UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE.
Macular Degeneration
Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study.
Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.
Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration.
Analysis of rare variants in the complement component 2 (C2) and factor B (BF) genes refine association for age-related macular degeneration (AMD).
Association of polymorphisms in C2, CFB and C3 with exudative age-related macular degeneration in a Korean population.
Association of Single-Nucleotide Polymorphisms in Age-Related Macular Degeneration With Pseudodrusen: Secondary Analysis of Data From the Comparison of AMD Treatments Trials.
CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.
Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration.
Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk.
Complement C3, C2, and factor B gene polymorphisms and age-related macular degeneration in a Greek cohort study.
Complement component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort.
Complement factor B gene polymorphisms and risk of age-related macular degeneration: A meta-analysis.
Complement factor B polymorphism (rs641153) and susceptibility to age-related macular degeneration: evidence from published studies.
Complement factor B polymorphism 32W protects against age-related macular degeneration.
Complement Factor B Polymorphism and the Phenotype of Early Age-related Macular Degeneration.
Complement research in the 18th-21st centuries: Progress comes with new technology.
Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study.
Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B.
Functional Evaluation of AMD-Associated Risk Variants of Complement Factor B.
Further assessment of the complement component 2 and factor B region associated with age-related macular degeneration.
Genetic variants in three genes and smoking show strong associations with susceptibility to exudative age-related macular degeneration in a Chinese population.
Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.
Interactions among different genetic loci in age-related macular degeneration.
Local production of the alternative pathway component, Factor B, is sufficient to promote laser-induced choroidal neovascularization.
Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the beaver dam eye study.
Multilocus analysis of age-related macular degeneration.
Plasma levels of complement proteins from the alternative pathway in patients with age-related macular degeneration are independent of Complement Factor H Tyr(402)His polymorphism.
Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.
Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population.
Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration.
RE: "THE ASSOCIATION BETWEEN COMPLEMENT COMPONENT 2/COMPLEMENT FACTOR B POLYMORPHISMS AND AGE-RELATED MACULAR DEGENERATION: A HuGE REVIEW AND META-ANALYSIS"
Re: "The Association Between Complement Component 2/Complement Factor B Polymorphisms and Age-related Macular Degeneration: A Huge Review and Meta-analysis"
Role of complement factor B rs4151667 (L9H) polymorphisms and its interactional role with CFH Y402H and C3 rs2230199 (R102G) risk variants in age-related macular degeneration: a case control study.
Significance of C2/CFB variants in age-related macular degeneration and polypoidal choroidal vasculopathy in a Japanese population.
Susceptibility to advanced age-related macular degeneration and alleles of complement factor H, complement factor B, complement component 2, complement component 3, and age-related maculopathy susceptibility 2 genes in a Mexican population.
The Association Between Complement Component 2/Complement Factor B Polymorphisms and Age-related Macular Degeneration: A HuGE Review and Meta-Analysis.
The effect of complement factor B gene variation on age-related macular degeneration in Iranian patients.
The Involvement of Complement Factor B and Complement Component C2 in an Indian Cohort with Age-Related Macular Degeneration.
The role of complement in AMD.
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration.
Variations in five genes and the severity of age-related macular degeneration: results from the Muenster aging and retina study.
[The genetic variability of complement system in pathogenesis of age-related macular degeneration].
Malaria
Complement changes in falciparum malaria infection.
Mania
Serological observations in patients suffering from acute manic episodes.
Mediastinitis
Relation of the bi-allelic NcoI restriction fragment length polymorphism within the tumour necrosis factor B gene to the development of mediastinitis.
Melanoma
Postoperative infections and variations of complement components in cancer patients.
Meningitis
Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.
Meningitis, Aseptic
Complement C3 and factor B cerebrospinal fluid concentrations in bacterial and aseptic meningitis.
Meningitis, Bacterial
Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.
Meningitis, Listeria
Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.
Meningococcal Infections
Complement abnormalities during an epidemic of group B meningococcal infection in children.
Complement levels in Brazilian children during and after meningococcal meningitis.
Recurrent meningococcal meningitis due to partial complement defects and poor anti-meningococcal antibody response.
Metabolic Syndrome
Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome.
Microscopic Polyangiitis
Complement profile in microscopic polyangiitis and granulomatosis with polyangiitis: analysis using sera from a nationwide prospective cohort study.
Mucocutaneous Lymph Node Syndrome
Early decreased plasma levels of factor B and C5a are important biomarkers in children with Kawasaki disease.
Multiple Sclerosis
Factor B (BF) allotypes and multiple sclerosis in north-east England.
Factor B alleles and multiple sclerosis.
Hypocomplementaemic and normocomplementaemic multiple sclerosis. Genetic determinism and association with specific HLA determinants (B18 and B7).
Murine complement C4 is not required for experimental autoimmune encephalomyelitis.
Normal distribution of factor B (Bf) allotypes in multiple sclerosis.
On the significance of C2, C4, and factor B polymorphisms in disease.
Optic neuritis and multiple sclerosis: do factor B alleles influence progression of disease?
The Aryl Hydrocarbon Receptor-Dependent TGF-?/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis.
Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Myelodysplastic Syndromes
Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia.
Myocardial Infarction
Complement factor B mutation-associated aHUS and myocardial infarction.
Low levels of vascular endothelial growth factor B predict left ventricular remodeling after acute myocardial infarction.
VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration.
Myocardial Ischemia
Association of factor B with ischemic heart disease (IHD).
Nasal Polyps
[The exploration of VEGF-B methylation in the nasal polyp].
Nasopharyngeal Carcinoma
Application of champedak mannose-binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma.
Neoplasm Metastasis
Bladder preservation therapy for muscle-invading bladder cancers on Radiation Therapy Oncology Group trials 8802, 8903, 9506, and 9706: vascular endothelial growth factor B overexpression predicts for increased distant metastasis and shorter survival.
Clinicopathological significance of platelet-derived growth factor B, platelet-derived growth factor receptor-?, and E-cadherin expression in gastric carcinoma.
DNA methylation data-based molecular subtype classification and prediction in patients with gastric cancer.
Echo planar MR imaging of the liver: comparison of images with and without motion probing gradients.
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Optimal bone health management strategies in patients with prostate cancer.
Vascular endothelial growth factor B coordinates metastasis of non-small cell lung cancer.
Neoplasms
A phase II and pharmacodynamic study of sunitinib in relapsed/refractory oesophageal and gastro-oesophageal cancers.
AICAR suppresses TNF-?-induced complement factor B in RPE cells.
Analysis of TGF-B and TGF-B-RII in Thyroid Neoplasms from the United States, Japan, and China.
Analysis of the first intron of TNFB gene by NcoI RFLP in Koreans.
Antiinflammatory effects of polypeptide growth factors. Platelet-derived growth factor, epidermal growth factor, and fibroblast growth factor inhibit the cytokine-induced expression of the alternative complement pathway activator factor B in human fibroblasts.
Biosynthesis and secretion of MHC class III gene products (complement C4 and factor B) in the exocrine pancreas.
Boeravinone B Protects Brain against Cerebral Ichemia Reperfusion Injury in Rats: Possible Role of Anti-inflammatory and Antioxidant.
Cell proliferation in human soft tissue tumors correlates with platelet-derived growth factor B chain expression: an immunohistochemical and in situ hybridization study.
Clinicopathological significance of platelet-derived growth factor B, platelet-derived growth factor receptor-?, and E-cadherin expression in gastric carcinoma.
Counter-regulatory effect of sodium butyrate on tumour necrosis factor-alpha (TNF-alpha)-induced complement C3 and factor B biosynthesis in human intestinal epithelial cells.
Cyclic AMP stimulates platelet-derived growth factor B chain mRNA expression in murine macrophage cell lines.
Cytokine Effects on Mechano-Induced Electrical Activity in Atrial Myocardium.
Dermatofibrosarcoma protuberans: a surgical disease with a molecular savior.
Detection and quantification of the control proteins of the alternative pathway of complement in 3T3-L1 adipocytes.
Diabetes prevents periodontitis-induced increases in gingival platelet derived growth factor-B and interleukin 1-beta in a rat model.
Effect of chrysin on methotrexate-induced testicular damage in rats.
Enhanced synthesis of factor B induced by tumor necrosis factor in human skin fibroblasts is decreased by IL-4.
Erythropoietin accelerates smooth muscle cell-rich vascular lesion formation in mice through endothelial cell activation involving enhanced PDGF-BB release.
Evidence for intrathecal synthesis of alternative pathway complement activation proteins in experimental meningitis.
Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor ? and Yes Kinase.
Human monocytes/macrophages release TNF-alpha in response to Ox-LDL.
Identification of a collagen 1 a-platelet-derived growth factor B gene abnormality may provide useful information about the biologic behavior of some fibrohistiocytic tumors.
Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma.
Identification of two candidate innate immune genes by transcriptional profiling and RNA interference in mouse mammary gland epithelial cells stimulated with lipopolysaccharide.
IDH1R132H is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment.
IL-13 results in differential regulation of the complement proteins C3 and factor B in tumour necrosis factor (TNF)-stimulated fibroblasts.
IL-17 regulates gene expression and protein synthesis of the complement system, C3 and factor B, in skin fibroblasts.
Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).
Immunostimulatory effects of low-dose cyclophosphamide are controlled by inducible nitric oxide synthase.
Increased inflammatory cytokines and new collagen formation in cutaneous tuberculosis and sarcoidosis.
Isolation of expressed sequence tags of skeletal muscle of neonatal healthy and splay leg piglets and mapping by somatic cell hybrid analysis.
Latent Transforming Growth Factor ? Binding Protein 2 (LTBP2) as a Novel Biomarker for the Diagnosis and Prognosis of Pancreatic Carcinoma.
Major histocompatibility complex phenotypes influence serum testosterone concentration.
Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C.
Mechanisms of pericyte recruitment in tumour angiogenesis: a new role for metalloproteinases.
Molecular mapping of the human major histocompatibility complex by pulsed-field gel electrophoresis.
New HIF2? inhibitors: potential implications as therapeutics for advanced pheochromocytomas and paragangliomas.
Nuclear factor kappa B (NFkB) pathway associated biomarkers in AIDS defining malignancies.
On the mechanism of antiinflammation induced by tumor transplantation, surgery, and irritant injection.
P27 deletion enhances hematopoiesis by paracrine action of IL22 secreted from bone marrow mesenchymal stem cells.
Pathomorphological Characteristics and Pathogenesis of Viral Hepatitis.
Polymorphism in the tumor necrosis factor B gene is associated with Palmoplantar pustulosis.
Polymorphism Ncol in tumor necrosis factor B is associated with fasting glycemia and lipid parameters in healthy non-obese caucasian subjects.
Postoperative infections and variations of complement components in cancer patients.
Prognostic potential of the preoperative plasma complement factor B in resected pancreatic cancer: A pilot study.
Proteomic Analysis of Cervical Cancer Cells Treated with Adenovirus-Mediated MDA-7.
Quantitative Proteomics of TRAMP Mice Combined with Bioinformatics Analysis Reveals That PDGF-B Regulatory Network Plays a Key Role in Prostate Cancer Progression.
Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells.
Regulation of synthesis of complement protein C4 in human fibroblasts: cell- and gene-specific effects of cytokines and lipopolysaccharide.
Relation of the bi-allelic NcoI restriction fragment length polymorphism within the tumour necrosis factor B gene to the development of mediastinitis.
Resveratrol delays polycystic kidney disease progression through attenuation of nuclear factor ?B-induced inflammation.
Resveratrol plays dual roles in pancreatic cancer cells.
Roquin2 suppresses breast cancer progression by inhibiting tumor angiogenesis via selectively destabilizing proangiogenic factors mRNA.
SDF-1? induces PDGF-B expression and the differentiation of bone marrow cells into pericytes.
Secretion of complement components of the alternative pathway (C3 and factor B) by the human alveolar type II epithelial cell line A549.
Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102.
Serpin Peptidase Inhibitor Clade A Member 1 as a Potential Marker for Malignancy in Insulinomas.
Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways.
Suppression of tumor metastasis by blockade of transforming growth factor beta signaling in bone marrow cells through a retroviral-mediated gene therapy in mice.
Synthesis of complement components C3 and factor B in human keratinocytes is differentially regulated by cytokines.
Synthesis of factor D by gastric cancer-derived cell lines.
TBK1 Inhibitor Exerts Antiproliferative Effect on Glioblastoma Multiforme Cells.
Temporal changes in gene expression following cryogenic rat brain injury.
Transcriptomic characterization reveals prognostic molecular signatures of sorafenib resistance in hepatocellular carcinoma.
Transformation from atypical chronic myeloid leukemia to chronic myelomonocytic leukemia as progression of myeloid neoplasm with platelet-derived growth factor ß rearrangement.
Tumor necrosis factor B (TNFB) genetic variants and its increased expression are associated with vitiligo susceptibility.
Tumor necrosis factor genomic polymorphism and outcome of acetaminophen (paracetamol)-induced acute liver failure.
Tumour necrosis factor B gene polymorphism in relation to complotype in couples with spontaneous abortions and in control families.
VEGFR-Mediated Cytotoxic Activity of Pulicaria undulata Isolated Metabolites: A Biological Evaluation and In Silico Study.
[Application of flow cytometry to chemotherapy of malignant brain tumor]
[Immune-testicular regulation and cytokines]
[The nervous system role in inhibition of hemopoiesis]
Nephritis
Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice.
Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.
Genetic study on HLA class II and class III region in the disease associated with IgA nephropathy.
Hypocomplementemia of membranoproliferative nephritis. Dependence of the nephritic factor reaction on properdin factor B.
Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis.
Nephritis, Hereditary
C3, C4, factor B and HLA-DR alpha mRNA expression in renal biopsy specimens from patients with IgA nephropathy.
Nephrosclerosis
Association between thrombotic microangiopathy and activated alternative complement pathway in malignant nephrosclerosis.
Nephrosis
Correlations between serum factor B and C3b inactivator levels in normal subjects and in patients with infections, nephrosis and hypocomplementaemic glomerulonephritis.
Nephrotic Syndrome
Assessment of serum factor B, serum opsonins, granulocyte chemotaxis, and infection in nephrotic syndrome of children.
Complement activation in renal disease.
Decreased serum factor B concentration associated with decreased opsonization of Escherichia coli in the idiopathic nephrotic syndrome.
Nervous System Diseases
Platelet-derived growth factor B chain is a novel target gene of cocaine-mediated Notch1 signaling: implications for HIV-associated neurological disorders.
Neuroblastoma
Expression of a complete and functional complement system by human neuronal cells in vitro.
Morphologic, Molecular, and Taxonomic Evolution of Renal Cell Carcinoma: A Conceptual Perspective With Emphasis on Updates to the 2016 World Health Organization Classification.
Neurofibroma
Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease.
Neurosyphilis
Complement protein isoforms in CSF as possible biomarkers for neurodegenerative disease.
Non-alcoholic Fatty Liver Disease
Plasma vascular endothelial growth factor B is elevated in non-alcoholic fatty liver disease patients and associated with blood pressure and renal dysfunction.
Obesity
Adipose tissue complement factor B promotes adipocyte maturation.
Complement Factor H is expressed in adipose tissue in association with insulin resistance.
Oligospermia
A rare Y chromosome constitutional rearrangement: a partial AZFb deletion and duplication within chromosome Yp in an infertile man with severe oligoasthenoteratozoospermia.
Optic Neuritis
A reassessment of the risk of multiple sclerosis developing in patients with optic neuritis after extended follow-up.
Optic neuritis and multiple sclerosis: do factor B alleles influence progression of disease?
Osteoarthritis
Alternative pathway complement activation in rheumatoid arthritis.
Complement biosynthesis in human synovial tissue.
Osteoporosis
Osteoporosis: the current status of mesenchymal stem cell-based therapy.
Osteosarcoma
Transcriptional regulation of the SIS/PDGF-B gene in human osteosarcoma cells by the Sp family of transcription factors.
Otitis Media
Complement aberrations in serum from children with otitis due to S. pneumoniae or H. influenzae.
Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2.
Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice.
Ovarian Hyperstimulation Syndrome
Platelet-derived growth factor B restores vascular barrier integrity and diminishes permeability in ovarian hyperstimulation syndrome.
Ovarian Neoplasms
Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor ?B and signal transducer and activator of transcription 3.
Identification and Confirmation of Differentially Expressed Fucosylated Glycoproteins in the Serum of Ovarian Cancer Patients Using a Lectin Array and LC-MS/MS.
PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor.
Pancreatic Neoplasms
Complement factor B regulates cellular senescence and is associated with poor prognosis in pancreatic cancer.
Prognostic potential of the preoperative plasma complement factor B in resected pancreatic cancer: A pilot study.
Pancreatitis
Complement activation and complement control proteins in acute pancreatitis.
Pancreatitis, Chronic
Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma.
Parasitemia
Plasma levels of proteins of the alternative complement pathway in inbred mice that differ in resistance to Trypanosoma congolense infections.
The alternative pathway of complement in sheep during the course of infection with Trypanosoma congolense and after Berenil treatment.
Parkinson Disease
Vascular endothelial growth factor B (VEGF-B) is up-regulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson's disease.
Pemphigoid, Bullous
Complement allotypes in Japanese patients with pemphigus and bullous pemphigoid.
Pemphigus
Complement allotypes in Japanese patients with pemphigus and bullous pemphigoid.
Peritonitis
Role of the classical pathway of complement activation in experimentally induced polymicrobial peritonitis.
Persistent Infection
The general stress response of Staphylococcus aureus promotes tolerance of antibiotics and survival in whole human blood.
Pleural Effusion
Deficient phagocytosis secondary to breakdown of opsonic factors in infected exudates.
Pneumococcal Infections
Alterations in serum opsonic activity and complement levels in pneumococcal disease.
Complement in pneumococcal infections with varying degrees of severity.
Complement system in pneumococcal infections.
Pneumonia
Complement activation in pneumonia.
Patients with rheumatoid arthritis and gold-induced pneumonitis express two high-risk major histocompatibility complex patterns.
Pneumonia, Pneumococcal
Complement levels in pneumococcal pneumonia.
Polycystic Kidney Diseases
The C-terminal tail of polycystin-1 regulates complement factor B expression by Signal Transducer and Activator of Transcription 1.
Polycystic Kidney, Autosomal Dominant
The C-terminal tail of polycystin-1 regulates complement factor B expression by Signal Transducer and Activator of Transcription 1.
Polycystic Ovary Syndrome
Local administration of platelet-derived growth factor B (PDGFB) improves follicular development and ovarian angiogenesis in a rat model of Polycystic Ovary Syndrome.
Serum vascular endothelial growth factor B is elevated in women with polycystic ovary syndrome and can be decreased with metformin treatment.
Pre-Eclampsia
Complement factor B activation in patients with preeclampsia.
Complement levels of C4, C3C, factor B, and C1 inactivator in peripheral and retroplacental blood of parturient women with EPH gestosis.
Screening preeclamptic cord plasma for proteins associated with decreased breast cancer susceptibility.
[Complement and immunoglobulin levels in pregnant women with EPH gestosis]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genetic predisposition to acute lymphocytic leukemia in American blacks. A Pediatric Oncology Group study.
Prostatic Neoplasms
Molecular Pathways in the Progression of Hormone-Independent and Metastatic Prostate Cancer.
Re: Clinical and immunological characteristics of patients with serologic progression of prostate cancer achieving long-term disease control with granulocyte-macrophage colony-stimulating factor: B. I. Rini, L. Fong, v. Weinberg, B. Kavanaugh and E. J. Small. J Urol 2006; 175: 2087-2091.
Proteinuria
Factor B and C3b inactivator clearance in patients with proteinuria.
Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice.
Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily.
Protoporphyria, Erythropoietic
Complement components in blood serum and suction blister fluid in erythropoietic protoporphyria.
Pulmonary Disease, Chronic Obstructive
Bronchial extracellular matrix from COPD patients induces altered gene expression in repopulated primary human bronchial epithelial cells.
Retinoic acid receptor alpha: One of plasma biomarkers associated with exacerbation of chronic obstructive pulmonary disease.
Pulmonary Fibrosis
A histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B gene.
Modulation of platelet-derived growth factor B mRNA abundance in macrophages by colchicine and dibutyryl-cAMP.
[Basic research in pulmonology]
Purpura
Complement abnormalities during an epidemic of group B meningococcal infection in children.
Genetic study on HLA class II and class III region in the disease associated with IgA nephropathy.
Serum complement components in Henoch-Schönlein purpura.
Purpura Fulminans
Magnitude of bacteremia and complement activation during Neisseria meningitidis infection: study of two co-primary cases with different clinical presentations.
Renal Insufficiency
Complement activation in patients with renal failure as detected through the quantitation of fragments of the complement proteins C3, C5, and factor B.
The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
Renal Insufficiency, Chronic
Regulated expression of complement factor B in the human kidney.
Retinoblastoma
Growth inhibition of transforming growth factor beta on human gastric carcinoma cells: receptor and postreceptor signaling.
Reye Syndrome
Hypocomplementemia in Reye syndrome: relationship to disease stage, circulating immune complexes, and C3b amplification loop protein synthesis.
Rhabdomyosarcoma
Expression of the complement alternative pathway by human myoblasts in vitro: biosynthesis of C3, factor B, factor H and factor I.
Sarcoidosis
Application of Proteomics in Sarcoidosis.
Sarcoma
Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression.
Imatinib mesylate in advanced dermatofibrosarcoma protuberans: pooled analysis of two phase II clinical trials.
Sarcoma, Ewing
Disodium Cromolyn and Anti-podoplanin Antibodies Strongly Inhibit Growth of BHK 21/C13-derived Fibrosarcoma in a Chick Embryo Chorioallantoic Membrane Model.
Seizures
Diffuse CNS involvement in systemic lupus erythematosus: intrathecal synthesis of the 4th component of complement.
Sepsis
Alterations in C3, C4, factor B, and related metabolites in septic shock.
Ba and Bb fragments of factor B activation: fragment production, biological activities, neoepitope expression and quantitation in clinical samples.
Complement activation and group B streptococcal infection in the newborn: similarities to endotoxin shock.
Complement components in neonatal sepsis.
Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis.
Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis.
Diminished IgG, but not complement C3 or C4 or factor B, precedes nosocomial bacterial sepsis in very low birth weight neonates.
Host defense against opportunist microorganisms following trauma. II. Changes in complement and immunoglobulins in patients with abdominal trauma and in septic patients without trauma.
Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C.
Platelet-derived growth factor B attenuates lethal sepsis through inhibition of inflammatory responses.
Recurrent septicemia associated with congenital deficiency of C2 and partial deficiency of factor B and the alternative complement pathway.
Sepsis score and acute-phase protein response as predictors of outcome in septic surgical patients.
Sepsis score and complement factor B for monitoring severely septic surgical patients and for predicting their survival.
Sigma factor B and RsbU are required for virulence in Staphylococcus aureus-induced arthritis and sepsis.
Splenic RNA and MicroRNA Mimics Promote Complement Factor B Production and Alternative Pathway Activation via Innate Immune Signaling.
Severe Dengue
Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse.
Shock, Septic
Alterations in C3, C4, factor B, and related metabolites in septic shock.
Complement activation in septic shock patients.
Magnitude of bacteremia and complement activation during Neisseria meningitidis infection: study of two co-primary cases with different clinical presentations.
Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C.
Silicosis
Evaluation of differential serum expression of three factors and pulmonary function in patients with silicosis.
Protein Expression Profile in Rat Silicosis Model Reveals Upregulation of PTPN2 and Its Inhibitory Effect on Epithelial-Mesenchymal Transition by Dephosphorylation of STAT3.
Sinusitis
Immunoglobulin classes, complement factors and circulating immune complexes in chronic sinusitis patients.
Spinal Cord Injuries
Complement C5a is detrimental to histological and functional locomotor recovery after spinal cord injury in mice.
Staphylococcal Infections
The alternative sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host.
Stomach Neoplasms
Effects of Nutrition Intervention on Total and Cancer Mortality: 25-Year Post-trial Follow-up of the 5.25-Year Linxian Nutrition Intervention Trial.
Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.
Stroke
Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats.
Synovitis
Activation of complement components C3 and factor B in synovial fluids.
Thrombasthenia
Type I Glanzmann's thrombasthenia segregates independently of Ss and Duffy systems and the A, B, C, factor B, C2 and C4 loci of the HLA complex.
Thrombocytopenia
Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.
Evaluation of complement regulatory components in patients with atypical hemolytic uremic syndrome.
[Hemorrhagic syndrome due to multiple defects in hemostasis. Deficiency of antihemophilic factor B associated with vascular changes and thrombocytopenia.]
Thrombosis
Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice.
Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection.
Immunoglobulin E, mast cell-specific tryptase and the complement system in sudden death from coronary artery thrombosis.
Thymoma
Differential chromatin looping regulates CD4 expression in immature thymocytes.
Toxoplasmosis, Cerebral
Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis.
Trypanosomiasis
Complement activation in patients with Gambian sleeping sickness.
Tuberculosis
Computational investigation of phytomolecules as resuscitation-promoting factor B (RpfB) inhibitors for clinical suppression of Mycobacterium tuberculosis dormancy reactivation.
Corrigendum: MtrA, an essential response regulator of the MtrAB two-component system, regulates the transcription of resuscitation-promoting factor B of Mycobacterium tuberculosis.
DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B elicits polyfunctional CD8(+) T cell responses.
Insilico analysis and molecular docking of resuscitation promoting factor B (RpfB) protein of Mycobacterium tuberculosis.
Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria.
Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis.
MtrA, an essential response regulator of the MtrAB two-component system, regulates the transcription of resuscitation-promoting factor B of Mycobacterium tuberculosis.
The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains.
Tuberculosis associated with HLA--B8, BfS in a Newfoundland community study.
Ureteral Obstruction
The effect of simvastatin and erythropoietin on renal fibrosis in rats with unilateral ureteral obstruction.
Urinary Bladder Neoplasms
Bladder preservation therapy for muscle-invading bladder cancers on Radiation Therapy Oncology Group trials 8802, 8903, 9506, and 9706: vascular endothelial growth factor B overexpression predicts for increased distant metastasis and shorter survival.
Eight-plex iTRAQ labeling and quantitative proteomic analysis for human bladder cancer.
Urticaria
A new complement factor B variant (BF S075) in Japanese.
Localized heat urticaria associated with a decrease in serum complement factor B (C3 proactivator).
Uveitis
Complement factor B expression profile in a spontaneous uveitis model.
Vaccinia
Vaccinia virus complement-control protein prevents antibody-dependent complement-enhanced neutralization of infectivity and contributes to virulence.
Varicose Veins
Polymorphisms of serum proteins in Japanese patients with vascular diseases. I. Factor XIIIB, plasminogen and complement types in primary varicose veins.
Vascular Diseases
The effects of aortic reconstruction and collagen impregnation of Dacron prostheses on the complement system.
Vasculitis
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis.
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Viremia
Complement components in kidney allograft recipients: relationship to cytomegalovirus infection.
Virus Diseases
Changes in complement alternative pathway components, factor B and factor H during dengue virus infection in the AG129 mouse.
Lymphomas complicating Sjögren's syndrome and hepatitis C virus infection may share a common pathogenesis: chronic stimulation of rheumatoid factor B cells.
Vitiligo
Tumor necrosis factor B (TNFB) genetic variants and its increased expression are associated with vitiligo susceptibility.
Whooping Cough
Activation of the complement cascade by Bordetella pertussis.
Wilms Tumor
Activation of the nuclear factor kappa B pathway following ischemia-reperfusion of the murine testis.