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Information on EC 3.4.21.26 - prolyl oligopeptidase and Organism(s) Amanita bisporigera and UniProt Accession E2JFG1

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.26 prolyl oligopeptidase
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This record set is specific for:
Amanita bisporigera
UNIPROT: E2JFG1 not found.
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Word Map
The taxonomic range for the selected organisms is: Amanita bisporigera
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Reaction Schemes
Hydrolysis of --Pro-/- and to a lesser extent --Ala-/- in oligopeptides
Synonyms
prolyl oligopeptidase, fibroblast activation protein, proline endopeptidase, post-proline cleaving enzyme, prolylendopeptidase, proline-specific endopeptidase, post-proline endopeptidase, glutenase, prolyl endoprotease, pepo2, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
endoprolylpeptidase
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peptidase, postproline endo-
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post-proline cleaving enzyme
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post-proline endopeptidase
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postproline endopeptidase
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postproline-cleaving enzyme
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proline endopeptidase
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proline-specific endopeptidase
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prolyl endopeptidase
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CAS REGISTRY NUMBER
COMMENTARY hide
72162-84-6
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Gly-L-Pro-4-nitroanilide + H2O
Gly-L-Pro + 4-nitroaniline
show the reaction diagram
-
-
-
?
Gly-L-Pro-4-nitroanilide + H2O
Gly-L-Pro + 4-nitroaniline
show the reaction diagram
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-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
isoform POPA
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
amanitin and isoform POPB are both present in certain hymenial cells
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
POPA_AMABI
761
0
86914
Swiss-Prot
Mitochondrion (Reliability: 1)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) cells
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Luo, H.; Hallen-Adams, H.E.; Scott-Craig, J.S.; Walton, J.D.
Colocalization of amanitin and a candidate toxin-processing prolyl oligopeptidase in Amanita basidiocarps
Eukaryot. Cell
9
1891-1900
2010
Amanita bisporigera (E2JFG1), Amanita bisporigera (E2JFG2)
Manually annotated by BRENDA team