Reference on EC 3.4.21.20 - cathepsin G
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tschesche, H.; Wenzel, H.R.; Engelbrecht, S.; Schnabel, E.
Cathepsin G
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
5
164-170
1984
Homo sapiens
-
Heck, L.W.; Rostand, K.S.; Hunter, F.A.; Bhown, A.
Isolation, characterization, and amino-terminal amino acid sequence analysis of human neutrophil cathepsin G from normal donors
Anal. Biochem.
158
217-227
1986
Homo sapiens
Virca, G.D.; Metz, G.; Schnebli, H.P.
Similarities between human and rat leukocyte elastase and cathepsin G
Eur. J. Biochem.
144
1-9
1984
Homo sapiens, Rattus norvegicus
Starkey, P.M.; Barret, A.J.
Neutral proteinases of human spleen. Purification and criteria for homogeneity of elastase and cathepsin G
Biochem. J.
155
255-263
1976
Homo sapiens
Braun, N.J.; Bodmer, J.L.; Virca, G.D.; Metz-Virca, G.; Maschler, R.; Bieth, J.G.; Schnebli, H.P.
Kinetic studies on the interaction of eglin c with human leukocyte elastase and cathepsin G
Biol. Chem. Hoppe-Seyler
368
299-308
1987
Homo sapiens
Stein, R.L.; Strimpler, A.M.
Slow-binding inhibition of chymotrypsin and cathepsin G by the peptide aldehyde chymostatin
Biochemistry
26
2611-2615
1987
Homo sapiens
Saklatvala, J.; Barrett, A.J.
Identification of proteinases in rheumatoid synovium. Detection of leukocyte elastase cathepsin G and another serine proteinase
Biochim. Biophys. Acta
615
167-177
1980
Homo sapiens
Lively, M.O.; Powers, J.C.
Specificity and reactivity of human granulocyte elastase and cathepsin G, porcine pancreatic elastase, bovine chymotrypsin and trypsin toward inhibition with sulfonyl fluorides
Biochim. Biophys. Acta
525
171-179
1978
Homo sapiens
Powers, J.C.; Gupton, B.F.; Harley, A.D.; Nishino, N.; Whitley, R.J.
Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G. Inhibition with peptide chloromethyl ketones
Biochim. Biophys. Acta
485
156-166
1977
Homo sapiens
Duranton, J.; Adam, C.; Bieth, J.G.
Kinetic mechanism of the inhibition of cathepsin G by alpha 1-antichymotrypsin and alpha 1-proteinase inhibitor
Biochemistry
37
11239-11245
1998
Homo sapiens
Bania, J.; Stachowiak, D.; Polanowski, A.
Primary structure and properties of the cathepsin G/chymotrypsin inhibitor from the larval hemolymph of Apis mellifera
Eur. J. Biochem.
262
680-687
1999
Homo sapiens
Ermolieff, J.; Boudier, C.; Laine, A.; Meyer, B.; Bieth, J.G.
Heparin protects cathepsin G against inhibition by protein proteinase inhibitor
J. Biol. Chem.
269
29502-29508
1994
Homo sapiens
Pidard, D.; Renesto, P.; Berndt, M.C.; Rabhi, S.; Clemetsons, K.J.; Chignard, M.
Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit
Biochem. J.
303
489-498
1994
Homo sapiens
Hogg, P.J.; Owensby, D.A.; Chesterman, C.N.
Thrombospondin 1 is a tight-binding competitive inhibitor of neutrophil cathepsin G. Determination of the kinetic mechanism of inhibition and localization of cathepsin G binding to the thrombospondin 1 type 3 repeats
J. Biol. Chem.
268
21811-21818
1993
Homo sapiens
Groutas, W.C.; Brubaker, M.J.; Verkataraman, R.; Epp, J.B.; Stang, M.A.; McClenahan, J.J.
Inhibitors of human neutrophil cathepsin G: structural and biochemical studies
Arch. Biochem. Biophys.
294
114-146
1992
Homo sapiens
-
Turkington, P.T.
Cathepsin G, a regulator of human vitamin K, dependent clotting factors and inhibitors
Thromb. Res.
67
147-155
1992
Homo sapiens
Hof, P.; Mayr, I.; Huber, R.; Korzus, E.; Potempa, J.; Travis, J.; Powers, J.C.; Bode, W.
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities
EMBO J.
15
5481-5491
1996
Homo sapiens
Mistry, R.; Snashall, P.D.; Totty, N.; Guz, A.; Tetley, T.D.
Purification and N-terminal amino acid sequence of sheep neutrophil cathepsin G and elastase
Arch. Biochem. Biophys.
368
7-13
1999
Ovis aries
Cavarra, E.; Santucci, A.; Lungarella, G.
Purification and N-terminal amino-acid sequence analysis of rabbit neutrophil cathepsin G
Biol. Chem. Hoppe-Seyler
376
371-377
1995
Oryctolagus cuniculus
Bjoerk, P.; Ohlsson, K.
Release of dog polymorphonuclear leukocyte cathepsin G, normally and in endotoxin and pancreatitic shock. Isolation and partial characterization of dog polymorphonuclear leukocyte cathepsin G
Biol. Chem. Hoppe-Seyler
372
419-426
1991
Canis lupus familiaris
Bjoerk, P.; Ohlsson, K.
Purification and N-terminal amino-acid sequence analysis of rat polymorphonuclear leukocyte cathepsin G
Biol. Chem. Hoppe-Seyler
371
595-601
1990
Rattus norvegicus
Maison, C.M.; Villiers, C.L.; Colomb, M.G.
Proteolysis of C3 on U937 cell plasma membranes. Purification of cathepsin G
J. Immunol.
147
921-926
1991
Homo sapiens
Gutschow, M.; Kuerschner, L.; Pietsch, M.; Ambrozak, A.; Neumann, U.; Gunther, R.; Hofmann, H.J.
Inhibition of cathepsin G by 2-amino-3,1-benzoxazin-4-ones: kinetic investigations and docking studies
Arch. Biochem. Biophys.
402
180-191
2002
Homo sapiens
Tani, K.; Murphy, W.J.; Chertov, O.; Oppenheim, J.J.; Wang, J.M.
The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice
Biochem. Biophys. Res. Commun.
282
971-976
2001
Homo sapiens
Berlov, M.N.; Lodygin, P.A.; Andreeva, Y.V.; Kokryakov, V.N.
Isolation and some physical and chemical properties of elastase and cathepsin G from dog neutrophils
Biochemistry (Moscow)
66
1008-1013
2001
Canis lupus familiaris
Vagnoni, L.M.; Gronostaj, M.; Kerrigan, J.E.
6-Acylamino-2-[(ethylsulfonyl)oxy]-1H-isoindole-1,3-diones mechanism-based inhibitors of human leukocyte elastase and cathepsin G: effect of chirality in the 6-acylamino substituent on inhibitory potency and selectivity
Bioorg. Med. Chem.
9
637-645
2001
Homo sapiens
Robledo, O.; Papaioannou, A.; Ochietti, B.; Beauchemin, C.; Legault, D.; Cantin, A.; King, P.D.; Daniel, C.; Alakhov, V.Y.; Potworowski, E.F.; St-Pierre, Y.
ICAM-1 isoforms: specific activity and sensitivity to cleavage by leukocyte elastase and cathepsin G
Eur. J. Immunol.
33
1351-1360
2003
Homo sapiens
Ledoux, D.; Merciris, D.; Barritault, D.; Caruelle, J.P.
Heparin-like dextran derivatives as well as glycosaminoglycans inhibit the enzymatic activity of human cathepsin G
FEBS Lett.
537
23-29
2003
Homo sapiens
Selim, T.E.; Ghoneim, H.R.; Abdel Ghaffar, H.A.; Colman, R.W.; Dela Cadena, R.A.
High molecular mass kininogen inhibits cathepsin G-induced platelet activation by forming a complex with cathepsin G
Hematol. J.
2
371-377
2001
Homo sapiens
Greco, M.N.; Hawkins, M.J.; Powell, E.T.; Almond, H.R., Jr.; Corcoran, T.W.; de Garavilla, L.; Kauffman, J.A.; Recacha, R.; Chattopadhyay, D.; Andrade-Gordon, P.; Maryanoff, B.E.
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design
J. Am. Chem. Soc.
124
3810-3811
2002
Homo sapiens
Sambrano, G.R.; Huang, W.; Faruqi, T.; Mahrus, S.; Craik, C.; Coughlin, S.R.
Cathepsin G activates protease-activated receptor-4 in human platelets
J. Biol. Chem.
275
6819-6823
2000
Homo sapiens
Goel, M.S.; Diamond, S.L.
Neutrophil cathepsin G promotes prothrombinase and fibrin formation under flow conditions by activating fibrinogen-adherent platelets
J. Biol. Chem.
278
9458-9463
2003
Homo sapiens
Moriuchi, H.; Moriuchi, M.; Fauci, A.S.
Cathepsin G, a neutrophil-derived serine protease, increases susceptibility of macrophages to acute human immunodeficiency virus type 1 infection
J. Virol.
74
6849-6855
2000
Homo sapiens
Biggs, J.R.; Yang, J.; Gullberg, U.; Muchardt, C.; Yaniv, M.; Kraft, A.S.
The human brm protein is cleaved during apoptosis: the role of cathepsin G
Proc. Natl. Acad. Sci. USA
98
3814-3819
2001
Homo sapiens
Bonnefoy, A.; Legrand, C.
Proteolysis of subendothelial adhesive glycoproteins (fibronectin, thrombospondin, and von Willebrand factor) by plasmin, leukocyte cathepsin G, and elastase
Thromb. Res.
98
323-332
2000
Homo sapiens
Sissi, C.; Lucatello, L.; Naggi, A.; Torri, G.; Palumbo, M.
Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G
Biochem. Pharmacol.
71
287-293
2006
Homo sapiens
Mezyk-Kope?, R.; Bzowska, M.; Bzowska, M.; Mickowska, B.; Mak, P.; Potempa, J.; Bereta, J.
Effects of elastase and cathepsin G on the levels of membrane and soluble TNFalpha
Biol. Chem.
386
801-811
2005
Homo sapiens
Yui, S.; Tomita, K.; Kudo, T.; Ando, S.; Yamazaki, M.
Induction of multicellular 3-D spheroids of MCF-7 breast carcinoma cells by neutrophil-derived cathepsin G and elastase
Cancer Sci.
96
560-570
2005
Homo sapiens
Helske, S.; Syvaeranta, S.; Kupari, M.; Lappalainen, J.; Laine, M.; Lommi, J.; Turto, H.; Maeyraenpaeae, M.; Werkkala, K.; Kovanen, P.T.; Lindstedt, K.A.
Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves
Eur. Heart J.
27
1495-1504
2006
Homo sapiens
Tralau, T.; Meyer-Hoffert, U.; Schroeder, J.M.; Wiedow, O.
Human leukocyte elastase and cathepsin G are specific inhibitors of C5a-dependent neutrophil enzyme release and chemotaxis
Exp. Dermatol.
13
316-325
2004
Homo sapiens
Raptis, S.Z.; Shapiro, S.D.; Simmons, P.M.; Cheng, A.M.; Pham, C.T.
Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering
Immunity
22
679-691
2005
Homo sapiens
Rivera-Marrero, C.A.; Stewart, J.; Shafer, W.M.; Roman, J.
The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli
Infect. Immun.
72
5712-5721
2004
Homo sapiens
Stefansson, S.; Yepes, M.; Gorlatova, N.; Day, D.E.; Moore, E.G.; Zabaleta, A.; McMahon, G.A.; Lawrence, D.A.
Mutants of plasminogen activator inhibitor-1 designed to inhibit neutrophil elastase and cathepsin G are more effective in vivo than their endogenous inhibitors
J. Biol. Chem.
279
29981-29987
2004
Homo sapiens
de Garavilla, L.; Greco, M.N.; Sukumar, N.; Chen, Z.W.; Pineda, A.O.; Mathews, F.S.; Di Cera, E.; Giardino, E.C.; Wells, G.I.; Haertlein, B.J.; Kauffman, J.A.; Corcoran, T.W.; Derian, C.K.; Eckardt, A.J.; Damiano, B.P.; Andrade-Gordon, P.; Maryanoff, B.E.
A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo
J. Biol. Chem.
280
18001-18007
2005
Homo sapiens (P08311), Homo sapiens
Shao, B.; Belaaouaj, A.; Verlinde, C.L.; Fu, X.; Heinecke, J.W.
Methionine sulfoxide and proteolytic cleavage contribute to the inactivation of cathepsin G by hypochlorous acid: an oxidative mechanism for regulation of serine proteinases by myeloperoxidase
J. Biol. Chem.
280
29311-29321
2005
Homo sapiens
Legedz, L7.; Randon, J.; Sessa, C.; Baguet, J.P.; Feugier, P.; Cerutti, C.; McGregor, J.; Bricca, G.
Cathepsin G is associated with atheroma formation in human carotid artery
J. Hypertens.
22
157-166
2004
Homo sapiens
Burster, T.; Beck, A.; Tolosa, E.; Marin-Esteban, V.; Roetzschke, O.; Falk, K.; Lautwein, A.; Reich, M.; Brandenburg, J.; Schwarz, G.; Wiendl, H.; Melms, A.; Lehmann, R.; Stevanovic, S.; Kalbacher, H.; Driessen, C.
Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes
J. Immunol.
172
5495-5503
2004
Homo sapiens
Sun, R.; Iribarren, P.; Zhang, N.; Zhou, Y.; Gong, W.; Cho, E.H.; Lockett, S.; Chertov, O.; Bednar, F.; Rogers, T.J.; Oppenheim, J.J.; Wang, J.M.
Identification of neutrophil granule protein cathepsin G as a novel chemotactic agonist for the G protein-coupled formyl peptide receptor
J. Immunol.
173
428-436
2004
Homo sapiens
Shimoda, N.; Fukazawa, N.; Nonomura, K.; Fairchild, R.L.
Cathepsin G is required for sustained inflammation and tissue injury after reperfusion of ischemic kidneys
Am. J. Pathol.
170
930-940
2007
Mus musculus
Lesner, A.; Wysocka, M.; Guzow, K.; Wiczk, W.; Legowska, A.; Rolka, K.
Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods
Anal. Biochem.
375
306-312
2008
Homo sapiens
Korkmaz, B.; Moreau, T.; Gauthier, F.
Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions
Biochimie
90
227-242
2008
Homo sapiens (P08311), Homo sapiens
Rafiq, K.; Hanscom, M.; Valerie, K.; Steinberg, S.F.; Sabri, A.
Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis
Circ. Res.
102
32-41
2008
Rattus norvegicus
Burster, T.; Beck, A.; Poeschel, S.; Oren, A.; Baechle, D.; Reich, M.; Roetzschke, O.; Falk, K.; Boehm, B.O.; Youssef, S.; Kalbacher, H.; Overkleeft, H.; Tolosa, E.; Driessen, C.
Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro
Immunology
121
82-93
2007
Homo sapiens, Mus musculus
Campbell, E.J.; Owen, C.A.
The sulfate groups of chondroitin sulfate- and heparan sulfate-containing proteoglycans in neutrophil plasma membranes are novel binding sites for human leukocyte elastase and cathepsin G
J. Biol. Chem.
282
14645-14654
2007
Homo sapiens
Rykl, J.; Thiemann, J.; Kurzawski, S.; Pohl, T.; Gobom, J.; Zidek, W.; Schlueter, H.
Renal cathepsin G and angiotensin II generation
J. Hypertens.
24
1797-1807
2006
Homo sapiens (P08311), Sus scrofa (Q95284), Sus scrofa
Lim, J.K.; Lu, W.; Hartley, O.; DeVico, A.L.
N-terminal proteolytic processing by cathepsin G converts RANTES/CCL5 and related analogs into a truncated 4-68 variant
J. Leukoc. Biol.
80
1395-1404
2006
Homo sapiens
Wysocka, M.; Legowska, A.; Bulak, E.; Jaskiewicz, A.; Miecznikowska, H.; Lesner, A.; Rolka, K.
New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P1 selected by combinatorial chemistry methods
Mol. Divers.
11
93-99
2007
Homo sapiens
Sedor, J.; Hogue, L.; Akers, K.; Boslaugh, S.; Schreiber, J.; Ferkol, T.
Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs
Pediatr. Res.
61
26-31
2006
Mus musculus
Miyata, J.; Tani, K.; Sato, K.; Otsuka, S.; Urata, T.; Lkhagvaa, B.; Furukawa, C.; Sano, N.; Sone, S.
Cathepsin G: the significance in rheumatoid arthritis as a monocyte chemoattractant
Rheumatol. Int.
27
375-382
2007
Homo sapiens
Gale, A.J.; Rozenshteyn, D.
Cathepsin G, a leukocyte protease, activates coagulation factor VIII
Thromb. Haemost.
99
44-51
2008
Homo sapiens
Peterszegi, G.; Texier, S.; Robert, A.M.; Moulias, R.; Robert, L.
Increased elastase and cathepsin G activity in activated lymphocytes from aged patients Role of denutrition and dementia
Arch. Gerontol. Geriatr.
25
285-298
2008
Homo sapiens
Sienczyk, M.; Lesner, A.; Wysocka, M.; Legowska, A.; Pietrusewicz, E.; Rolka, K.; Oleksyszyn, J.
New potent cathepsin G phosphonate inhibitors
Bioorg. Med. Chem.
16
8863-8867
2008
Homo sapiens
Wilson, T.J.; Nannuru, K.C.; Futakuchi, M.; Sadanandam, A.; Singh, R.K.
Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand
Cancer Res.
68
5803-5811
2008
Mus musculus, Mus musculus BALB/c
Wilson, T.J.; Nannuru, K.C.; Singh, R.K.
Cathepsin G recruits osteoclast precursors via proteolytic activation of protease-activated receptor-1
Cancer Res.
69
3188-3195
2009
Homo sapiens, Mus musculus
Stoeckle, C.; Sommandas, V.; Adamopoulou, E.; Belisle, K.; Schiekofer, S.; Melms, A.; Weber, E.; Driessen, C.; Boehm, B.O.; Tolosa, E.; Burster, T.
Cathepsin G is differentially expressed in primary human antigen-presenting cells
Cell. Immunol.
255
41-45
2009
Homo sapiens
Mambole, A.; Baruch, D.; Nusbaum, P.; Bigot, S.; Suzuki, M.; Lesavre, P.; Fukuda, M.; Halbwachs-Mecarelli, L.
The cleavage of neutrophil leukosialin (CD43) by cathepsin G releases its extracellular domain and triggers its intramembrane proteolysis by presenilin/gamma-secretase
J. Biol. Chem.
283
23627-23635
2008
Homo sapiens (P08311)
Korkmaz, B.; Attucci, S.; Juliano, M.A.; Kalupov, T.; Jourdan, M.L.; Juliano, L.; Gauthier, F.
Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates
Nat. Protoc.
3
991-1000
2008
Homo sapiens
Dabek, M.; Ferrier, L.; Roka, R.; Gecse, K.; Annahazi, A.; Moreau, J.; Escourrou, J.; Cartier, C.; Chaumaz, G.; Leveque, M.; Ait-Belgnaoui, A.; Wittmann, T.; Theodorou, V.; Bueno, L.
Luminal cathepsin g and protease-activated receptor 4: a duet involved in alterations of the colonic epithelial barrier in ulcerative colitis
Am. J. Pathol.
175
207-214
2009
Homo sapiens
Wilson, T.J.; Nannuru, K.C.; Futakuchi, M.; Singh, R.K.
Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1
Cancer Lett.
288
162-169
2010
Mus musculus
Farberman, M.M.; Akers, K.T.; Malone, J.P.; Erdman-Gilmore, P.; Townsend, R.R.; Ferkol, T.
Airway proteins involved in bacterial clearance susceptible to cathepsin G proteolysis
Eur. Respir. J.
35
410-417
2010
Mus musculus
Burster, T.; Macmillan, H.; Hou, T.; Schilling, J.; Truong, P.; Boehm, B.O.; Zou, F.; Lau, K.; Strohman, M.; Schaffert, S.; Busch, R.; Mellins, E.D.
Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules
Immunology
130
436-46
2010
Homo sapiens
Tausch, L.; Henkel, A.; Siemoneit, U.; Poeckel, D.; Kather, N.; Franke, L.; Hofmann, B.; Schneider, G.; Angioni, C.; Geisslinger, G.; Skarke, C.; Holtmeier, W.; Beckhaus, T.; Karas, M.; Jauch, J.; Werz, O.
Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense
J. Immunol.
183
3433-3442
2009
Homo sapiens (P08311), Homo sapiens
Kudo, T.; Kigoshi, H.; Hagiwara, T.; Takino, T.; Yamazaki, M.; Yui, S.
Cathepsin G, a neutrophil protease, induces compact cell-cell adhesion in MCF-7 human breast cancer cells
Mediators Inflamm.
2009
850940
2009
Homo sapiens
Wilson, T.J.; Nannuru, K.C.; Singh, R.K.
Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction
Mol. Cancer Res.
7
1224-1233
2009
Mus musculus
Reich, M.; Lesner, A.; Legowska, A.; Sienczyk, M.; Oleksyszyn, J.; Boehm, B.O.; Burster, T.
Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells
Mol. Immunol.
46
2994-2999
2009
Homo sapiens
Burster, T.; Macmillan, H.; Hou, T.; Boehm, B.O.; Mellins, E.D.
Cathepsin G: roles in antigen presentation and beyond
Mol. Immunol.
47
658-665
2010
Homo sapiens, Mus musculus
Palesch, D.; Sienczyk, M.; Oleksyszyn, J.; Reich, M.; Wieczerzak, E.; Boehm, B.O.; Burster, T.
Was the serine protease cathepsin G discovered by S. G. Hedin in 1903 in bovine spleen?
Acta Biochim. Pol.
58
39-44
2011
Bos taurus
Korkmaz, B.; Jegot, G.; Lau, L.C.; Thorpe, M.; Pitois, E.; Juliano, L.; Walls, A.F.; Hellman, L.; Gauthier, F.
Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates
FEBS J.
278
2635-2646
2011
Homo sapiens (P08311), Homo sapiens
Raymond, W.W.; Trivedi, N.N.; Makarova, A.; Ray, M.; Craik, C.S.; Caughey, G.H.
How immune peptidases change specificity: cathepsin G gained tryptic function but lost efficiency during primate evolution
J. Immunol.
185
5360-5368
2010
Homo sapiens, Mus musculus
Siao, S.C.; Li, K.J.; Hsieh, S.C.; Wu, C.H.; Lu, M.C.; Tsai, C.Y.; Yu, C.L.
Tamm-Horsfall glycoprotein enhances PMN phagocytosis by binding to cell surface-expressed lactoferrin and cathepsin G that activates MAP kinase pathway
Molecules
16
2119-2134
2011
Homo sapiens
Zou, F.; Schaefer, N.; Palesch, D.; Bruecken, R.; Beck, A.; Sienczyk, M.; Kalbacher, H.; Sun, Z.; Boehm, B.O.; Burster, T.
Regulation of cathepsin G reduces the activation of proinsulin-reactive T cells from type 1 diabetes patients
PLoS ONE
6
e22815
2011
Homo sapiens
Perrin, J.; Lecompte, T.; Tournier, A.; Morlon, L.; Marchand-Arvier, M.; Vigneron, C.
In vitro effects of human neutrophil cathepsin G on thrombin generation: Both acceleration and decreased potential
Thromb. Haemost.
104
514-522
2010
Homo sapiens
Wang, J.; Sjoeberg, S.; Tang, T.T.; Ooerni, K.; Wu, W.; Liu, C.; Secco, B.; Tia, V.; Sukhova, G.K.; Fernandes, C.; Lesner, A.; Kovanen, P.T.; Libby, P.; Cheng, X.; Shi, G.P.
Cathepsin G activity lowers plasma LDL and reduces atherosclerosis
Biochim. Biophys. Acta
1842
2174-2183
2014
Homo sapiens (P08311), Homo sapiens, Mus musculus (P28293)
Cohen-Mazor, M.; Mazor, R.; Kristal, B.; Sela, S.
Elastase and cathepsin G from primed leukocytes cleave vascular endothelial cadherin in hemodialysis patients
BioMed Res. Int.
2014
459640
2014
Homo sapiens (P08311), Homo sapiens
Woloszynek, J.C.; Hu, Y.; Pham, C.T.
Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions
J. Biol. Chem.
287
34101-34109
2012
Homo sapiens (P08311)
Faraday, N.; Schunke, K.; Saleem, S.; Fu, J.; Wang, B.; Zhang, J.; Morrell, C.; Dore, S.
Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils
PLoS ONE
8
e71447
2013
Homo sapiens (P08311), Homo sapiens, Mus musculus (P28293), Mus musculus
Gudmann, N.S.; Manon-Jensen, T.; Sand, J.M.B.; Diefenbach, C.; Sun, S.; Danielsen, A.; Karsdal, M.A.; Leeming, D.J.
Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease
Biochem. Biophys. Res. Commun.
503
1284-1290
2018
Homo sapiens
Groborz, K.; Kolt, S.; Kasperkiewicz, P.; Drag, M.
Internally quenched fluorogenic substrates with unnatural amino acids for cathepsin G investigation
Biochimie
166
103-111
2019
Homo sapiens
Gao, S.; Zhu, H.; Yang, H.; Zhang, H.; Li, Q.; Luo, H.
The role and mechanism of cathepsin G in dermatomyositis
Biomed. Pharmacother.
94
697-704
2017
Homo sapiens
Guo, J.; Tu, J.; Hu, Y.; Song, G.; Yin, Z.
Cathepsin G cleaves and activates IL-36gamma and promotes the inflammation of psoriasis
Drug Des. Devel. Ther.
13
581-588
2019
Homo sapiens
Penczek, A.; Sienczyk, M.; Wirtz, C.R.; Burster, T.
Cell surface cathepsin G activity differs between human natural killer cell subsets
Immunol. Lett.
179
80-84
2016
Homo sapiens
Fu, Z.; Thorpe, M.; Alemayehu, R.; Roy, A.; Kervinen, J.; de Garavilla, L.; Abrink, M.; Hellman, L.
Highly selective cleavage of cytokines and chemokines by the human mast cell chymase and neutrophil cathepsin G
J. Immunol.
198
1474-1483
2017
Homo sapiens
Eipper, S.; Steiner, R.; Lesner, A.; Sienczyk, M.; Palesch, D.; Halatsch, M.E.; Zaczynska, E.; Heim, C.; Hartmann, M.D.; Zimecki, M.; Wirtz, C.R.; Burster, T.
Lactoferrin is an allosteric enhancer of the proteolytic activity of cathepsin G
PLoS ONE
11
e0151509
2016
Homo sapiens
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