Reference on EC 3.4.21.114 - equine arterivirus serine peptidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Snijder, E.J.; Wassenaar, A.L.; Spaan, W.J.
Proteolytic processing of the N-terminal region of the equine arteritis virus replicase
Adv. Exp. Med. Biol.
342
227-232
1993
equine arteritis virus (P19811)
Snijder, E.J.; Wassenaar, A.L.; van Dinten, L.C.; Spaan, W.J.; Gorbalenya, A.E.
The arterivirus nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteases
J. Biol. Chem.
271
4864-4871
1996
equine arteritis virus (P19811), equine arteritis virus, equine arteritis virus Bucyrus (P19811)
Barrette-Ng, I.H.; Ng, K.K.; Mark, B.L.; Van Aken, D.; Cherney, M.M.; Garen, C.; Kolodenko, Y.; Gorbalenya, A.E.; Snijder, E.J.; James, M.N.
Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole
J. Biol. Chem.
277
39960-39966
2002
equine arteritis virus (P19811), equine arteritis virus
den Boon, J.A.; Snijder, E.J.; Chirnside, E.D.; de Vries, A.A.; Horzinek, M.C.; Spaan, W.J.
Equine arteritis virus is not a togavirus but belongs to the coronaviruslike superfamily
J. Virol.
65
2910-2920
1991
equine arteritis virus (P19811)
van Dinten, L.C.; Wassenaar, A.L.; Gorbalenya, A.E.; Spaan, W.J.; Snijder, E.J.
Processing of the equine arteritis virus replicase ORF1b protein: identification of cleavage products containing the putative viral polymerase and helicase domains
J. Virol.
70
6625-6633
1996
equine arteritis virus, equine arteritis virus Bucyrus
Wassenaar, A.L.; Spaan, W.J.; Gorbalenya, A.E.; Snijder, E.J.
Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine protease
J. Virol.
71
9313-9322
1997
equine arteritis virus
van Dinten, L.C.; Rensen, S.; Gorbalenya, A.E.; Snijder, E.J.
Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and Is essential for virus replication
J. Virol.
73
2027-2037
1999
equine arteritis virus
van Aken, D.; Snijder, E.J.; Gorbalenya, A.E.
Mutagenesis analysis of the nsp4 main proteinase reveals determinants of arterivirus replicase polyprotein autoprocessing
J. Virol.
80
3428-3437
2006
equine arteritis virus
van Aken, D.; Benckhuijsen, W.E.; Drijfhout, J.W.; Wassenaar, A.L.; Gorbalenya, A.E.; Snijder, E.J.
Expression, purification, and in vitro activity of an arterivirus main proteinase
Virus Res.
120
97-106
2006
equine arteritis virus
Tian, X.; Lu, G.; Gao, F.; Peng, H.; Feng, Y.; Ma, G.; Bartlam, M.; Tian, K.; Yan, J.; Hilgenfeld, R.; Gao, G.F.
Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
J. Mol. Biol.
392
977-993
2009
porcine reproductive and respiratory syndrome virus (A1E8J1), porcine reproductive and respiratory syndrome virus
Ma, Z.; Wang, Y.; Zhao, H.; Xu, A.T.; Wang, Y.; Tang, J.; Feng, W.H.
Porcine reproductive and respiratory syndrome virus nonstructural protein 4 induces apoptosis dependent on its 3C-like serine protease activity
PLoS ONE
8
e69387
2013
porcine reproductive and respiratory syndrome virus (Q91F54), porcine reproductive and respiratory syndrome virus
Chen, J.; Wang, D.; Sun, Z.; Gao, L.; Zhu, X.; Guo, J.; Xu, S.; Fang, L.; Li, K.; Xiaoa, S.
Arterivirus nsp4 antagonizes interferon beta production by proteolytically cleaving NEMO at multiple sites
J. Virol.
93
e00385
2019
equine arteritis virus, porcine reproductive and respiratory syndrome virus (E3V2B5)
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