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Disease on EC 3.4.19.1 - acylaminoacyl-peptidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome.
Alopecia Areata
Expression of T6 antigen on keratinocytes in alopecia areata.
Alzheimer Disease
Low Erythrocyte Levels of Proteasome and Acyl-Peptide Hydrolase (APEH) Activities in Alzheimer's Disease: A Sign of Defective Proteostasis?
Anemia, Aplastic
[Change of expression of cell adhesion molecules CD11a and CD49d in patients with chronic aplastic anemia before and after therapy]
Arthritis
Presence of neuroreceptors in normal and diseased temporo-mandibular joints.
Arthritis, Rheumatoid
A comparative phenotypical analysis of rheumatoid nodules and rheumatoid synovium with special reference to adhesion molecules and activation markers.
Asthma
[A study of CD23 expression and regulation in the patients with asthma]
Breast Neoplasms
Detection of estrogen receptor proteins in breast tumors using an improved APAAP immunohistochemical technique.
Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease.
[Detection of micrometastases in axillary lymph nodes of node-negative breast cancer patients and its clinical significance]
Carcinogenesis
VEGF-, KIT protein- and neutral endopeptidase (NEP/CD10)-positive myofibroblasts-precursors of angiogenesis in chorioangiomas?
Carcinoma
Application of a Novel Method of Double APAAP Staining With Subsequent Quantitative Image Analysis to the Examination of Integrin Expression in Undifferentiated-type Gastric Carcinomas.
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines.
Immunocytochemical typing of fine needle aspirates by means of alkaline phosphatase anti-alkaline phosphatase method. A study of 16 selected patients.
Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).
Immunohistochemical characterization of the pancreatic cellular infiltrate in normal pancreas, chronic pancreatitis and pancreatic carcinoma.
In situ hybridization detection of single-copy human papillomavirus on isolated cells, using a catalyzed signal amplification system: GenPoint.
K-ras mutations (codon 12) are not involved in down-regulation of MHC class-I genes in colon carcinomas.
Lack of correlation between codon 12 K-ras mutations and major histocompatibility complex antigens in bronchogenic carcinomas.
MHC class I antigens and tumour-infiltrating leucocytes in laryngeal cancer: long-term follow-up.
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
The gene from the short arm of chromosome 3, at D3F15S2, frequently deleted in renal cell carcinoma, encodes acylpeptide hydrolase.
[Significance of serum beta-hCG as a tumor marker for stomach carcinoma]
[Study on the immune state of patients with laryngeal carcinoma]
Carcinoma, Ehrlich Tumor
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines.
Carcinoma, Renal Cell
The gene from the short arm of chromosome 3, at D3F15S2, frequently deleted in renal cell carcinoma, encodes acylpeptide hydrolase.
Carcinoma, Squamous Cell
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
Cataract
Lens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase.
Cervical Intraepithelial Neoplasia
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
Cholangitis, Sclerosing
Biliary expression of heat shock protein: a non-specific feature of chronic cholestatic liver diseases.
Tissue distribution of autoantigen specific for primary sclerosing cholangitis.
Cholesteatoma
[Hyperproliferation-associated keratin 16 expression in cholesteatoma]
Colorectal Neoplasms
Expression of CD44, ICAM-1 and N-CAM in colorectal cancer. Correlation with the tumor stage and the phenotypical characteristics of tumor-infiltrating lymphocytes.
Epilepsy
Influence of acylpeptide hydrolase polymorphisms on valproic acid level in Chinese epilepsy patients.
Epiretinal Membrane
Expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on proliferating vascular endothelial cells in diabetic epiretinal membranes.
Immunochemical studies of epiretinal membranes using APAAP complexes: evidence for macrophage involvement in traumatic proliferative vitreoretinopathy.
Gingivitis
Variational expression of functionally different macrophage markers (27E10, 25F9, RM3/1) in normal gingiva and inflammatory periodontal disease.
Glioma
Immunohistochemical detection and correlation between MHC antigen and cell-mediated immune system in recurrent glioma by APAAP method.
Graves Disease
Infiltrating gamma/delta T-cell receptor-positive lymphocytes in Hashimoto's thyroiditis, Graves' disease and papillary thyroid cancer.
Hashimoto Disease
Infiltrating gamma/delta T-cell receptor-positive lymphocytes in Hashimoto's thyroiditis, Graves' disease and papillary thyroid cancer.
Hemangioma
VEGF-, KIT protein- and neutral endopeptidase (NEP/CD10)-positive myofibroblasts-precursors of angiogenesis in chorioangiomas?
Hepatitis
Biliary expression of heat shock protein: a non-specific feature of chronic cholestatic liver diseases.
Hodgkin Disease
Immunocytochemical typing of fine needle aspirates by means of alkaline phosphatase anti-alkaline phosphatase method. A study of 16 selected patients.
[Immunoenzyme cytochemical methods, monoclonal antibodies and lectins in the diagnosis of tumors of the lymphoid tissue in children]
Influenza, Human
[Rapid detection for antigens of respiratory tract viruses by using series of monoclonal antibody]
Leiomyosarcoma
Expression of myogenic marker proteins in human leiomyosarcoma.
Leprosy
Immunohistologic assessment of cytokine production of infiltrating cells in various forms of leprosy.
Leukemia
Clinical usefulness of immunocytochemical detection of myeloperoxidase in undifferentiated and biphenotypic acute leukemias.
Double immunoenzymatic APAAP staining for the detection of leukemia-associated immunophenotypes.
Immunocytochemical typing of fine needle aspirates by means of alkaline phosphatase anti-alkaline phosphatase method. A study of 16 selected patients.
Immunophenotyping of acute myeloid leukemia using monoclonal antibodies and the alkaline phosphatase-antialkaline phosphatase technique.
Monoclonal antibody study of Philadelphia chromosome-positive blastic leukemias using the alkaline phosphatase anti-alkaline phosphatase (APAAP) technic.
[Comparison of clinical usefulness of immunophenotyping of leukemia using the immunofluorescence and immunoenzyme APAAP methods]
[Dynamic analysis of cell surface markers in acute leukemias unclassified with immunologic criteria]
[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]
Leukemia, Biphenotypic, Acute
[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]
Leukemia, Hairy Cell
Immunocytochemical typing of fine needle aspirates by means of alkaline phosphatase anti-alkaline phosphatase method. A study of 16 selected patients.
Leukemia, Myeloid
Interleukin-4 inhibits proliferation of human leukemic megakaryoblast cell line MHH 225.
Leukemia, Myeloid, Acute
Immunophenotyping of acute myeloid leukemia by immuno-alkaline phosphatase (APAAP) labeling with a panel of antibodies.
P-glycoprotein expression in acute myeloblastic leukemia analyzed by immunocytochemistry and flow cytometry.
The protein expression of Bcl-2, Bax, Fas/Apo-1 in acute myeloid leukemia.
[Comparison of clinical usefulness of immunophenotyping of leukemia using the immunofluorescence and immunoenzyme APAAP methods]
[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]
[Multidrug resistant P-glycoprotein expression on acute nonlymphocytic leukemia cells at diagnosis]
Liver Cirrhosis, Biliary
Biliary expression of heat shock protein: a non-specific feature of chronic cholestatic liver diseases.
Liver Diseases, Alcoholic
Biliary expression of heat shock protein: a non-specific feature of chronic cholestatic liver diseases.
Lung Diseases, Interstitial
[Immunoenzymatic labeling of monoclonal antibodies for surface antigens of T-cells using immune complexes of APAAP in patients with interstitial lung disease]
Lymphatic Metastasis
Lack of MHC class I antigens and tumour aggressiveness of the squamous cell carcinoma of the larynx.
Lymphedema
[Effects of microwave baking on the immunological cells in primary lymphedema patients]
Lymphoma
[Immunoenzyme cytochemical methods, monoclonal antibodies and lectins in the diagnosis of tumors of the lymphoid tissue in children]
[Use of an immunoenzyme method with monoclonal antibodies in cytologic studies for the optimal diagnosis of non-Hodgkin's lymphoma in children]
Lymphoma, Non-Hodgkin
Immunocytochemical typing of fine needle aspirates by means of alkaline phosphatase anti-alkaline phosphatase method. A study of 16 selected patients.
Melanoma
APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome.
Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma.
Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours.
Multiple Myeloma
Specificity and sensitivity of immunocytochemistry for detecting P-glycoprotein in haematological malignancies.
The expression of the multidrug transporter P-170 glycoprotein in remission phase is associated with early and resistant relapse in multiple myeloma.
Myelodysplastic Syndromes
The significance of Ki-67, BrdU and OKT9 expression in determination of myelodysplastic syndromes by use of APAAP technique.
[Study on apoptosis in myelodysplastic syndromes by DNA in situ end labelling combined with APAAP]
Nasopharyngeal Carcinoma
[The expression of HLA, Epstein-Barr virus nuclear antigen and the infiltration of T lymphocyte subsets in nasopharyngeal biopsy tissues]
Neoplasm Metastasis
Application of a Novel Method of Double APAAP Staining With Subsequent Quantitative Image Analysis to the Examination of Integrin Expression in Undifferentiated-type Gastric Carcinomas.
Lack of MHC class I antigens and tumour aggressiveness of the squamous cell carcinoma of the larynx.
Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours.
Neoplasm Micrometastasis
Prevalence of bone marrow micrometastases in esophagogastric cancer patients with and without neoadjuvant chemoradiotherapy.
Neoplasms
A new approach to phenotyping disseminated tumor cells: methodological advances and clinical implications.
Analysis of immune response in oral tumors.
APAAP immunophenotyping of haematological malignancies.
Assessment of immunophenotype of potentially cytotoxic tumor infiltrating cells in laryngeal carcinoma.
Class I major histocompatibility complex antigens and tumor ploidy in breast and bronchogenic carcinomas.
Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines.
Expression of adhesion molecules on the endothelium of normal tissue vessels and vascular tumors.
Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review.
Immunocytochemical phenotyping of disseminated tumor cells in bone marrow by uPA receptor and CK18: investigation of sensitivity and specificity of an immunogold/alkaline phosphatase double staining protocol.
Immunohistochemical detection of vinculin in human rhabdomyosarcomas.
Immunohistologic assessment of cytokine production of infiltrating cells in various forms of leprosy.
Infiltrating gamma/delta T-cell receptor-positive lymphocytes in Hashimoto's thyroiditis, Graves' disease and papillary thyroid cancer.
Lack of correlation between codon 12 K-ras mutations and major histocompatibility complex antigens in bronchogenic carcinomas.
Lack of MHC class I antigens and tumour aggressiveness of the squamous cell carcinoma of the larynx.
MHC class I antigens and tumour-infiltrating leucocytes in laryngeal cancer: long-term follow-up.
MMP-1 and MMP-2 in the cervix uteri in different steps of malignant transformation--an immunohistochemical study.
Optimization of immunohistochemical detection of P-glycoprotein in chronic lymphoid disorders.
Phase-1 studies of malariotherapy for HIV infecton.
Phosphonic Analogs of Alanine as Acylpeptide Hydrolase Inhibitors.
Primary systemic therapy does not eradicate disseminated tumor cells in breast cancer patients.
RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells.
The immunophenotyping of extramedullary myeloid cell tumors in paraffin-embedded tissue sections.
Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease.
Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours.
[CD 143 expression in benign and malignant vascular tumors]
[Effect of Astragalus polysaccharides in promoting neutrophil-vascular endothelial cell adhesion and expression of related adhesive molecules]
[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]
[Study on the immune state of patients with laryngeal carcinoma]
[Tumor cell dissemination in bone marrow and peritoneal cavity. An immunocytochemical study of patients with stomach or colorectal carcinoma]
Nephrotic Syndrome
[A study on the relationship between respiratory tract viruses antigen in peripheral blood mononuclear cells and their antibody from children with steroid-sensitive and simple nephrotic syndrome]
Neuroblastoma
Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide.
[Detection of minimal residual disease in children with neuroblastoma]
Osteoarthritis
Presence of neuroreceptors in normal and diseased temporo-mandibular joints.
Osteosarcoma
Selective inhibition of acylpeptide hydrolase in SAOS-2 osteosarcoma cells: is this enzyme a viable anticancer target?
Pancreatitis, Chronic
Immunohistochemical characterization of the pancreatic cellular infiltrate in normal pancreas, chronic pancreatitis and pancreatic carcinoma.
Paramyxoviridae Infections
[Rapid detection for antigens of respiratory tract viruses by using series of monoclonal antibody]
Periodontitis
Variational expression of functionally different macrophage markers (27E10, 25F9, RM3/1) in normal gingiva and inflammatory periodontal disease.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Immunophenotype and cytochemical reactions of acute lymphoblastic leukemia in Thai children.
[Immunoenzyme cytochemical methods, monoclonal antibodies and lectins in the diagnosis of tumors of the lymphoid tissue in children]
[The prognostic significance of P-glycoprotein in children with acute lymphoblastic leukemia and neuroblastoma]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
[Comparison of clinical usefulness of immunophenotyping of leukemia using the immunofluorescence and immunoenzyme APAAP methods]
Pulmonary Disease, Chronic Obstructive
[Changes of immunologic function in patients with COPD induced chronic cor pulmonale]
Pulmonary Heart Disease
[Changes of immunologic function in patients with COPD induced chronic cor pulmonale]
Retinal Detachment
Immunohistochemistry of cellular proliferation in eyes with longstanding retinal detachment.
Rhabdomyosarcoma, Embryonal
Immunohistochemical detection of vinculin in human rhabdomyosarcomas.
Rheumatic Fever
Distribution of cells bearing B-cell alloantigen(s) in North Indian rheumatic fever/rheumatic heart disease patients.
Rheumatoid Nodule
A comparative phenotypical analysis of rheumatoid nodules and rheumatoid synovium with special reference to adhesion molecules and activation markers.
Sarcoma
[Significance of differential nuclear expression of Ki-67 in adult soft tissue sarcomas]
Temporomandibular Joint Disorders
Presence of neuroreceptors in normal and diseased temporo-mandibular joints.
Tuberculosis
Pregranulomatous phase of sarcoidosis: Immunohistochemical diagnosis.
Vitreoretinopathy, Proliferative
Immunochemical studies of epiretinal membranes using APAAP complexes: evidence for macrophage involvement in traumatic proliferative vitreoretinopathy.