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Information on EC 3.4.16.4 - serine-type D-Ala-D-Ala carboxypeptidase
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3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidaseSpecify your search results
Word Map
- 3.4.16.4
- beta-lactams
- peptidoglycan
- staphylococcus
- aureus
- streptococcus
- pneumonia
-
methicillin-resistant
- cephalosporin
- gg
- methicillin
-
penicillin-resistant
- ampicillin
- bilirubin
-
sortase
-
gamma-glutamyl
- vancomycin
- cefotaxime
- oxacillin
-
transpeptidation
-
pneumococci
- faecium
- ceftriaxone
- carbapenems
- transglycosylase
- imipenem
-
penicillin-susceptible
- ceftazidime
- murein
-
methicillin-susceptible
- benzylpenicillin
- meropenem
- cefoxitin
- acyl-enzyme
- muropeptides
-
mic90s
- cefixime
-
cephems
- piperacillin
-
ampicillin-resistant
-
lpxtg
- cefuroxime
- penicillinase
- aztreonam
-
vancomycin-resistant
- cefaclor
-
beta-lactamase-negative
- synthesis
-
sccmec
-
beta-lactamase-producing
- nitrocefin
- sulbactam
- medicine
- analysis
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Preferential cleavage: (Ac)2-L-Lys-D-Ala-/-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine
Synonyms
transpeptidase, penicillin-binding protein, pbp2x, pbp1a, pbp1b, penicillin binding proteins, pbp 2, pbp 3, pbp 5, dd-peptidase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
carboxypeptidase I
-
-
-
-
CPase
-
-
-
-
D-alanine carboxypeptidase
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-
-
-
D-alanine carboxypeptidase I
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-
-
-
D-alanyl carboxypeptidase
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-
-
-
D-alanyl-D-alanine carboxypeptidase
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-
-
-
D-Alanyl-D-alanine hydrolase
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-
-
-
D-alanyl-D-alanine peptidase
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-
-
-
D-alanyl-D-alanine-carboxypeptidase
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-
-
-
D-alanyl-D-alanine-cleaving peptidase
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-
-
-
D-alanyl-D-alanine-cleaving-peptidase
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-
-
-
DD-Carboxypeptidase
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-
-
-
DD-peptidase
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-
-
-
DD-transpeptidase
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-
-
-
PBP-5*
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-
-
-
PBP-6B
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-
-
-
PBP5
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-
-
-
penicillin binding protein 5
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-
-
-
VanX
-
-
-
-
VanY
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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CAS REGISTRY NUMBER
COMMENTARY
9077-67-2
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acidosis
Phosphate-independent glutaminase from rat kidney. Partial purification and identity with gamma-glutamyltranspeptidase.
Acidosis
[Clinical features and MYO5B mutations of a family affected by microvillus inclusion disease].
Acquired Immunodeficiency Syndrome
A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii.
Acute Kidney Injury
Is urinary ?-glutamyl transpeptidase superior to urinary neutrophil gelatinase-associated lipocalin for early prediction of acute kidney injury after liver transplantation?
Acute Kidney Injury
Monitoring of plasma creatinine and urinary ?-glutamyl transpeptidase improves detection of acute kidney injury by more than 20%.
Acute Kidney Injury
Utility of urinary alkaline phosphatase and ?-glutamyl transpeptidase in diagnosing acute kidney injury in dogs.
Adenoma, Bile Duct
[Usefulness of carbohydrate antigen 19-9 (CA19-9) for the diagnosis of cholangioma. As a role of screening patients with the elevation of serum alkaline phosphatase, leucine aminopeptidase and/or gamma-glutamyl transpeptidase]
Alagille Syndrome
Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis.
Albuminuria
Relationship between dietary patterns and risk factors for cardiovascular disease in patients with type 2 diabetes mellitus: a cross-sectional study.
Alcohol-Related Disorders
Recognition of alcoholic liver disease in a district general hospital.
Anemia
A Multicenter Study of Docetaxel at a Dose of 100 mg/m2 in Japanese Patients with Advanced or Recurrent Breast Cancer.
Anemia, Hemolytic
Cholestasis and Hepatic Failure in a Neonate: A Case Report of Severe Pyruvate Kinase Deficiency.
Aneurysm, Infected
Molecular diagnosis and characterization of a culture-negative mycotic aneurysm due to ST54 Haemophilus influenzae type b with PBP 3 alterations.
Aortic Aneurysm, Abdominal
The clinical utility window for acute kidney injury biomarkers in the critically ill.
Arthritis, Experimental
Treatment with anti-gamma-glutamyl transpeptidase antibody attenuates osteolysis in collagen-induced arthritis mice.
Asthma
Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.
Atrial Fibrillation
Nonalcoholic Fatty Liver Disease Is Associated with Increased Atrial Fibrillation Risk in an Elderly Chinese Population: A Cross-Sectional Study.
Bacteremia
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase.
Bacteremia
Identification of a patient with Streptococcus pneumoniae bacteremia and meningitis by the polymerase chain reaction (PCR).
Bacterial Infections
Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism.
Bacterial Infections
Influence of the T to S mutation at the STMK motif on antibiotic resistance of penicillin binding protein 1A: A comprehensive computational study.
Biliary Atresia
Diagnostic value of anti-smooth muscle antibodies and liver enzymes in differentiation of extrahepatic biliary atresia and idiopathic neonatal hepatitis.
Biliary Atresia
Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study.
Biliary Tract Diseases
[Indication for repeated surgery on the biliary ducts. II. Significance of serum gamma-glutamyl transpeptidase activity determination in the diagnosis of anicteric forms of biliary tract diseases]
Breast Neoplasms
[Carcinoembryonic antigen and gammaglutamyl transpeptidase in postoperative breast cancer]
Brucellosis
Brucellosis-related acute pancreatitis: A rare complication of a universal disease.
Carcinogenesis
Molecular characterization of tumor associated antigen in mice exposed to a hepatocarcinogen.
Carcinogenesis
[Selected characteristics of carcinogenesis in Wistar rats induced by aflatoxin B1. I. Morphological changes and glutamyl transpeptidase activity]
Carcinoma
Biological markers as an aid in the clinical management of patients with liver metastases.
Carcinoma
Fruiting Bodies of Antrodia cinnamomea and Its Active Triterpenoid, Antcin K, Ameliorates N-Nitrosodiethylamine-Induced Hepatic Inflammation, Fibrosis and Carcinogenesis in Rats.
Carcinoma, Hepatocellular
-Glutamyl transpeptidase in transplantable, chemically induced rat hepatomas and "spontaneous" mouse hepatomas.
Carcinoma, Hepatocellular
?-Glutamyl transpeptidase is a heavily N-glycosylated heterodimer in HepG2 cells.
Carcinoma, Hepatocellular
A novel "AIE + ESIPT" near-infrared nanoprobe for the imaging of ?-glutamyl transpeptidase in living cells and the application in precision medicine.
Carcinoma, Hepatocellular
A novel prognostic index-neutrophil times ?-glutamyl transpeptidase to lymphocyte ratio (N?LR) predicts outcome for patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Advances of diagnostic and mechanistic studies of ?-glutamyl transpeptidase in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Change in ?-glutamyl transpeptidase activity as a useful tool in identifying a group of patients with elevated risk of hepatocellular carcinoma development after DAA treatment of chronic hepatitis C.
Carcinoma, Hepatocellular
Combined preoperative albumin-bilirubin (ALBI) and serum ?-glutamyl transpeptidase (GGT) predicts the outcome of hepatocellular carcinoma patients following hepatic resection.
Carcinoma, Hepatocellular
Diagnostic value of gamma-glutamyl transpeptidase to alkaline phosphatase ratio combined with gamma-glutamyl transpeptidase to aspartate aminotransferase ratio and alanine aminotransferase to aspartate aminotransferase ratio in alpha-fetoprotein-negative hepatocellular carcinoma.
Carcinoma, Hepatocellular
Hepatocellular Carcinoma Size: Platelets, ?-Glutamyl Transpeptidase, and Alkaline Phosphatase.
Carcinoma, Hepatocellular
Predictive ability of shear wave elastography for pruritus in chronic hepatitis C patients with sustained virological response.
Carcinoma, Hepatocellular
Preoperative ?-glutamyl transpeptidase to platelet ratio (GPR) is an independent prognostic factor for HBV-related hepatocellular carcinoma after curative hepatic resection.
Carcinoma, Hepatocellular
Prognostic predictors for patients with hepatocellular carcinoma receiving adjuvant transcatheter arterial chemoembolization.
Carcinoma, Hepatocellular
Prognostic value of ?-glutamyl transpeptidase to albumin ratio combined with aspartate aminotransferase to lymphocyte ratio in patients with hepatocellular carcinoma after hepatectomy.
Carcinoma, Hepatocellular
Subcellular localization and isolation of gamma-glutamyltransferase from rat hepatoma cells.
Carcinoma, Hepatocellular
The Combination of Age, International Standardized Ratio, Albumin and ?-Glutamyl Transpeptidase (AIAG), Tumor Size and Alpha Fetoprotein (AFP) Stage as the Prognostic Model for Hepatitis B-Related Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
The evaluation of tumour marker proteins in the diagnosis of primary hepatocellular carcinoma.
Carcinoma, Small Cell
Biological markers as an aid in the clinical management of patients with liver metastases.
Celiac Disease
[Etiology and pathogenesis of celiac disease. I. Behavior of gamma-glutamyl transpeptidase at different stages of gluten-dependent celiac disease]
Cellulitis
A Multicenter Study of Docetaxel at a Dose of 100 mg/m2 in Japanese Patients with Advanced or Recurrent Breast Cancer.
Cholangiocarcinoma
Characteristics of printing company workers newly diagnosed with occupational cholangiocarcinoma.
Cholangiocarcinoma
Screening and surveillance for occupational cholangiocarcinoma in workers exposed to organic solvents.
Cholangitis
Hepatic injury following reduced intensity unrelated cord blood transplantation for adult patients with hematological diseases.
Cholangitis
Multiple comet tail artifacts in the liver: a case of congenital hepatic fibrosis showing unusual biliary appearance.
Cholangitis, Sclerosing
Effect of Measuring ?-Glutamyl Transpeptidase and Using Smoflipid in a Parenteral Nutrition Infusion in a Patient With Severe Malabsorption and Overlapping Primary Sclerosing Cholangitis and Ulcerative Colitis.
Cholera
A novel peptidoglycan binding protein crucial for PBP1A-mediated cell wall biogenesis in Vibrio cholerae.
Cholestasis
A comparative study of endoscopic ultrasonography versus endoscopic retrograde cholangiopancreatography in children with chronic liver disease.
Cholestasis
A prospective study on the value of ultrasound, computed tomography and endoscopic retrograde cholangiopancreatography in the diagnosis of unjaundiced cholestasis.
Cholestasis
Altered integrity of hepatocyte tight junctions in rats with triptolide-induced cholestasis.
Cholestasis
Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis.
Cholestasis
Cholestasis and Hepatic Failure in a Neonate: A Case Report of Severe Pyruvate Kinase Deficiency.
Cholestasis
Clinical and ABCB11 profiles in Korean infants with progressive familial intrahepatic cholestasis.
Cholestasis
Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress.
Cholestasis
Identification of potential biomarkers in cholestasis and the therapeutic effect of melatonin by metabolomics, multivariate data and pathway analyses.
Cholestasis
[Benign recurrent cholestasis. Apropos of a case with normal serum gamma-glutamyl transpeptidase level]
Cholestasis
[Choleretic and cholagogic effect of sulphuric sulfate water from the springs of Tobiano in cholestasis in alcohol related liver diseases]
Cholestasis
[Cholestasis in pregnancy and normal serum gammaglutamyl transpeptidase activity]
Cholestasis
[Influence of cholestasis on enzymatic induction with phenobarbital and other enzymatic aspects: experimental studies on guinea pigs]
Cholestasis, Intrahepatic
?-Glutamyl transpeptidase level as a screening marker among diverse etiologies of infantile intrahepatic cholestasis.
Cholestasis, Intrahepatic
Clinical and ABCB11 profiles in Korean infants with progressive familial intrahepatic cholestasis.
Cholestasis, Intrahepatic
Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study.
Cholestasis, Intrahepatic
[Benign recurrent intrahepatic cholestasis. Bile salts and gamma-glutamyl transpeptidase]
Colic
Detecting acute kidney injury in horses by measuring the concentration of symmetric dimethylarginine in serum.
Colitis, Ulcerative
Effect of Measuring ?-Glutamyl Transpeptidase and Using Smoflipid in a Parenteral Nutrition Infusion in a Patient With Severe Malabsorption and Overlapping Primary Sclerosing Cholangitis and Ulcerative Colitis.
Colonic Neoplasms
Severe sinusoidal lesions: a serious and overlooked complication of oxaliplatin-containing chemotherapy?
Colorectal Neoplasms
Prognostic model built on blood-based biomarkers in patients with metastatic colorectal cancer.
Communicable Diseases
Alterations of pbp1a, pbp2b, and pbp2x in Streptococcus pneumoniae isolates from children with otolaryngological infectious disease in the Sapporo district of Japan.
Coronavirus Infections
The impact of coronavirus disease 2019 (COVID-19) on liver injury in China: A systematic review and meta-analysis.
COVID-19
Lymphocyte subset alterations with disease severity, imaging manifestation, and delayed hospitalization in COVID-19 patients.
Cross Infection
Pan-?-Lactam Resistance Development in Pseudomonas aeruginosa Clinical Strains: Molecular Mechanisms, Penicillin-Binding Protein Profiles, and Binding Affinities.
Cross Infection
Purification, properties, and kinetics of enzymatic acylation with beta-lactams of soluble penicillin-binding protein 2a. A major factor in methicillin-resistant Staphylococcus aureus.
Cystic Fibrosis
Correction of gamma-glutamyl transpeptidase deficiency in amniotic fluid of some cystic fibrosis fetuses by mixing with nondeficient fluids.
Cystitis
Morphological studies of Escherichia coli in the urine of patients with acute simple cystitis treated with aztreonam.
Cysts
Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.
Dehydration
The Bacillus subtilis dacB gene, encoding penicillin-binding protein 5*, is part of a three-gene operon required for proper spore cortex synthesis and spore core dehydration.
Dehydration
The SpmA/B and DacF proteins of Clostridium perfringens play important roles in spore heat resistance.
Dental Caries
Effects of missense mutations in sortase A gene on enzyme activity in Streptococcus mutans.
Diabetes Mellitus
A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia.
Diabetes Mellitus
Early detection of hepatocellular carcinoma in patients with diabetes mellitus.
Diabetes Mellitus, Type 2
Formulation for Effective Screening and Management of Nonalcoholic Steatohepatitis: Noninvasive NAFLD Management Strategy.
Digestive System Diseases
Radioimmunoassay of serum glycocholic acid, standard laboratory tests of liver function and liver biopsy findings: comparative study of children with liver disease.
Digestive System Diseases
[Evaluation of determination of -glutamyl transpeptidase ( -GT) in hepatobiliary diseases]
Digestive System Diseases
[Gamma-glutamyl transpeptidase. 2. The clinical evaluation of serum gamma-glutamyl transpeptidase in hepatobiliary disease]
Duodenal Ulcer
Role of ?-glutamyl transpeptidase in the pathogenesis of Helicobacter pylori infection.
Dyslipidemias
Association between ratio of ?-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study.
Dyslipidemias
Comparison of the relationships of alcoholic and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia.
Dyslipidemias
The clinical significance of insulin resistance in non-diabetic patients with early forms of non-alcoholic fatty liver disease.
Endocarditis
Beta-lactam resistance mechanisms of methicillin-resistant Staphylococcus aureus.
Endocarditis
Effects of inner-membrane-associated beta-lactamase on penicillin-binding protein assays. Study of stably derepressed Pseudomonas aeruginosa strains from experimental endocarditis.
Endocarditis
LB11058, a new cephalosporin with high penicillin-binding protein 2a affinity and activity in experimental endocarditis due to homogeneously methicillin-resistant Staphylococcus aureus.
Endocarditis
The Global Regulon sarA Regulates ?-lactam Antibiotic Resistance In Methicillin-resistant Staphylococcus aureus (MRSA) In Vitro and In Endovascular Infections.
Exanthema
Safety and Tolerability of Bismuthyl Ecabet Suspension, a Novel Anti-Ulcer Agent, following Single and Multiple Oral Dose Administration in Healthy Chinese Subjects.
Fatty Liver
A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome.
Fatty Liver
Association of the Trp64Arg mutation of the beta3-adrenergic receptor with fatty liver and mild glucose intolerance in Japanese subjects.
Fatty Liver
Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity.
Fatty Liver
Efficacy and effectiveness of liver screening program to detect fatty liver in the periodic health check-ups.
Fatty Liver
Favorable effect of sodium-glucose cotransporter 2 inhibitor, dapagliflozin, on non-alcoholic fatty liver disease compared with pioglitazone.
Fatty Liver
Non-alcoholic fatty liver disease, liver biomarkers and stroke risk: The Reasons for Geographic and Racial Differences in Stroke cohort.
Fatty Liver
[Choleretic and cholagogic effect of sulphuric sulfate water from the springs of Tobiano in cholestasis in alcohol related liver diseases]
Fatty Liver, Alcoholic
Comparison of the relationships of alcoholic and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia.
Galactosemias
Abnormalities of retinal metabolism in diabetes or galactosemia. II. Comparison of gamma-glutamyl transpeptidase in retina and cerebral cortex, and effects of antioxidant therapy.
Gastritis
Role of ?-glutamyl transpeptidase in the pathogenesis of Helicobacter pylori infection.
Gonorrhea
Rapid detection of the mosaic structure of the Neisseria gonorrhoeae penA Gene, which is associated with decreased susceptibilities to oral cephalosporins.
Gram-Negative Bacterial Infections
Septal Class A Penicillin-Binding Protein Activity and ld-Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter baumannii.
Heart Arrest
The clinical utility window for acute kidney injury biomarkers in the critically ill.
Heart Diseases
A redox-metabolic-electrical remodeling in the diseased left and right ventricle: direct clinical implications in heart disease and beyond. Focus on "Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts".
Hepatic Encephalopathy
Fufang Banmao Capsule, a Traditional Chinese Medicinal Formulation, Enhances the Survival of Patients with Hepatocellular Carcinoma and Vp3-4 Portal Vein Tumor Thrombosis Undergoing Supportive Treatment.
Hepatitis
?-glutamyl transpeptidase in men and alanine aminotransferase in women are the most suitable parameters among liver function tests for the prediction of metabolic syndrome in nonviral hepatitis and nonfatty liver in the elderly.
Hepatitis
Associated factors in modulating aflatoxin B1-albumin adduct level in three Chinese populations.
Hepatitis
Diagnostic value of anti-smooth muscle antibodies and liver enzymes in differentiation of extrahepatic biliary atresia and idiopathic neonatal hepatitis.
Hepatitis
Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study.
Hepatitis
Sensitive and selective SERS probe for detecting the activity of ?-glutamyl transpeptidase in serum.
Hepatitis
The Combination of Age, International Standardized Ratio, Albumin and ?-Glutamyl Transpeptidase (AIAG), Tumor Size and Alpha Fetoprotein (AFP) Stage as the Prognostic Model for Hepatitis B-Related Hepatocellular Carcinoma.
Hepatitis
[Use of the serum enzymes gamma-glutamyl transpeptidase and pseudocholinesterase in hepatic pathology]
Hepatitis B
A Non-invasive Model for Predicting Liver Inflammation in Chronic Hepatitis B Patients With Normal Serum Alanine Aminotransferase Levels.
Hepatitis B
Artificial neural network model to predict post-hepatectomy early recurrence of hepatocellular carcinoma without macroscopic vascular invasion.
Hepatitis B
Elevated post-transfusion serum transaminase values associated with a highly significant trend for increasing prevalence of anti-Vesivirus antibody in Korean patients.
Hepatitis B
Level of hepatitis B surface antigen might serve as a new marker to predict hepatocellular carcinoma recurrence following curative resection in patients with low viral load.
Hepatitis B
Prognostic factors in patients with hepatitis B virus-related hepatocellular carcinoma undergoing nucleoside analog antiviral therapy.
Hepatitis B
Prognostic predictors for patients with hepatocellular carcinoma receiving adjuvant transcatheter arterial chemoembolization.
Hepatitis B
Epidemiologic trends in HBV infections at a reference centre in Turkey: an 11-year retrospective analysis.
Hepatitis B, Chronic
Alanine Aminotransferase Influencing Performances of Routine Available Tests Detecting Hepatitis B Related Cirrhosis.
Hepatitis B, Chronic
Gamma-glutamyl transpeptidase to cholinesterase and platelet ratio in predicting significant liver fibrosis and cirrhosis of chronic hepatitis B.
Hepatitis B, Chronic
The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurements of liver fibrosis in HIV-positive patients with chronic hepatitis B in West Africa. Response to: 'The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa' by Lemoine et al.
Hepatitis C
Chronic hepatitis C and interferon alfa therapy: predictors of long term response.
Hepatitis C
MicroRNA profiles in serum samples from patients with stable cirrhosis and miRNA-21 as a predictor of transplant-free survival.
Hepatitis C, Chronic
Change in ?-glutamyl transpeptidase activity as a useful tool in identifying a group of patients with elevated risk of hepatocellular carcinoma development after DAA treatment of chronic hepatitis C.
Hepatitis C, Chronic
Interference of diabetes on the association of ?-glutamyl transpeptidase to platelet ratio with liver fibrosis in chronic hepatitis C.
Hepatitis, Alcoholic
[Role of hepatitis C virus in the genesis of hepatic lesions observed in alcoholic patients with liver cirrhosis]
Hepatitis, Autoimmune
A comparative study of endoscopic ultrasonography versus endoscopic retrograde cholangiopancreatography in children with chronic liver disease.
Hepatitis, Autoimmune
Three paediatric cases of primary sclerosing cholangitis treated with ursodeoxycholic acid and sulphasalazine.
Hepatitis, Chronic
[The significance of serum gamma-glutamyl transpeptidase determination in the differentiation of icterus of various etiologies]
Hyperglycemia
A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia.
Hyperglycemia
Phase I trial of GBS-01 for advanced pancreatic cancer refractory to gemcitabine.
Hyperglycemia
Phase I/II Study of Radiologic Hepatic Arterial Infusion of Fluorouracil Plus Systemic Irinotecan for Unresectable Hepatic Metastases from Colorectal Cancer: Japan Clinical Oncology Group Trial 0208-DI.
Hypersensitivity
Gradual alterations in cell wall structure and metabolism in vancomycin-resistant mutants of Staphylococcus aureus.
Hypersensitivity
The highly conserved serine threonine kinase StkP of Streptococcus pneumoniae contributes to penicillin susceptibility independently from genes encoding penicillin-binding proteins.
Hypertension
A Multicenter Study of Docetaxel at a Dose of 100 mg/m2 in Japanese Patients with Advanced or Recurrent Breast Cancer.
Hypertension
Comparison of Hemoglobin Alc, Glycated Albumin and Fasting Plasma Glucose for Prediction of Arterial Stiffness in Chinese Adults.
Hypertension
Comparison of the relationships of alcoholic and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia.
Hypertension
Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity.
Hypertension, Portal
Noncirrhotic Portal Hypertension in HIV-Infected Patients: A Case Control Evaluation and Review of the Literature.
Hypertension, Portal
Peginterferon plus ribavirin and sustained virological response in HCV-related cirrhosis: outcomes and factors predicting response.
Hypertension, Portal
Prognostic predictors for patients with hepatocellular carcinoma receiving adjuvant transcatheter arterial chemoembolization.
Hyperthyroidism
[Evolution of serum gammaglutamyl transpeptidase activity in treated hyperthyroid and hypothyroid patients]
Hypoalbuminemia
Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques.
Hypotension
The clinical utility window for acute kidney injury biomarkers in the critically ill.
Hypothyroidism
[Evolution of serum gammaglutamyl transpeptidase activity in treated hyperthyroid and hypothyroid patients]
Infections
?-lactam resistance: The role of low molecular weight penicillin binding proteins, ?-lactamases and ld-transpeptidases in bacteria associated with respiratory tract infections.
Infections
A Molecular Docking and Dynamics Study to Screen Potent Anti-Staphylococcal Compounds Against Ceftaroline Resistant MRSA.
Infections
A new hepatitis C virus-like flavivirus in patients with cryptogenic liver disease associated with elevated GGT and alkaline phosphatase serum levels.
Infections
A potential bio-control agent from baical skullcap root against listeriosis via the inhibition of sortase A and listeriolysin O.
Infections
A streptococcal penicillin-binding protein is critical for resisting innate airway defenses in the neonatal lung.
Infections
Associated factors in modulating aflatoxin B1-albumin adduct level in three Chinese populations.
Infections
Ceftaroline Is Active against Heteroresistant Methicillin-Resistant Staphylococcus aureus Clinical Strains despite Associated Mutational Mechanisms and Intermediate Levels of Resistance.
Infections
Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.
Infections
Development of an immunochromatographic strip for simple detection of penicillin-binding protein 2'.
Infections
Disruption of allosteric response as an unprecedented mechanism of resistance to antibiotics.
Infections
Dual ?-lactam combination therapy for multi-drug resistant Pseudomonas aeruginosa infection: enhanced efficacy in vivo and comparison with monotherapies of penicillin-binding protein inhibition.
Infections
Influence of soybean trypsin inhibitor on small bowel enzyme activities during rotavirus infection in malnourished infant mice.
Infections
Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection.
Infections
Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques.
Infections
Poorly Cross-Linked Peptidoglycan in MRSA Due to mecA Induction Activates the Inflammasome and Exacerbates Immunopathology.
Infections
Prognostic predictors for patients with hepatocellular carcinoma receiving adjuvant transcatheter arterial chemoembolization.
Infections
Reduced in vitro susceptibility of Streptococcus pyogenes to beta-lactam antibiotics associated with mutations in the pbp2x gene is geographically widespread.
Infections
Role of ?-glutamyl transpeptidase in the pathogenesis of Helicobacter pylori infection.
Infections
Spermine and oxacillin stress response on the cell wall synthesis and the global gene expression analysis in Methicillin-resistance Staphylococcus aureus.
Infections
The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurements of liver fibrosis in HIV-positive patients with chronic hepatitis B in West Africa. Response to: 'The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa' by Lemoine et al.
Infections
Transpeptidation-Mediated Assembly of Tripartite Split Green Fluorescent Protein for Label-Free Assay of Sortase Activity.
Infections
Transpeptidation-mediated single-particle imaging assay for sensitive and specific detection of sortase with dark-field optical microscopy.
Insulin Resistance
A 12-week aerobic exercise program without energy restriction improves intrahepatic fat, liver function and atherosclerosis-related factors.
Insulin Resistance
A Nomogram for Predicting Non-Alcoholic Fatty Liver Disease in Obese Children.
Insulin Resistance
Assessment of atherosclerosis in obese adolescents: Positive correlation of mean platelet volume and carotid intima media thickness.
Insulin Resistance
Association between ratio of ?-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study.
Insulin Resistance
Associations between sitting time and non-alcoholic fatty liver diseases in Chinese male workers: a cross-sectional study.
Insulin Resistance
Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial.
Insulin Resistance
Efficacy of orlistat in non-alcoholic fatty liver disease: A systematic review and meta-analysis.
Insulin Resistance
Genetic loci associated with lipid concentrations and cardiovascular risk factors in a Korean population.
Insulin Resistance
Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats.
Insulin Resistance
Noninvasive estimation of disease activity and liver fibrosis in nonalcoholic fatty liver disease using anthropometric and biochemical characteristics, including insulin, insulin resistance, and 13C-methionine breath test.
Insulin Resistance
Prevalence of nonalcoholic steatohepatitis in Japanese patients with morbid obesity undergoing bariatric surgery.
Insulin Resistance
Serum betatrophin concentrations are significantly increased in overweight but not in obese or type 2 diabetic individuals.
Insulin Resistance
The effect of alcohol intake on insulin sensitivity in men: a randomized controlled trial.
Insulin Resistance
The serum level of soluble CD26/dipeptidyl peptidase 4 increases in response to acute hyperglycemia after an oral glucose load in healthy subjects: association with high-molecular weight adiponectin and hepatic enzymes.
Insulin Resistance
Tyrosine levels are associated with insulin resistance in patients with nonalcoholic fatty liver disease.
Ischemic Stroke
Non-alcoholic fatty liver disease, liver biomarkers and stroke risk: The Reasons for Geographic and Racial Differences in Stroke cohort.
Kidney Diseases
The contribution of epithelial-mesenchymal transition to renal fibrosis differs among kidney disease models.
Leptospirosis
Synthesis, Leptospirocidal Activity and QSAR Analysis of Novel Quinoxaline Derivatives.
Leukopenia
A Multicenter Study of Docetaxel at a Dose of 100 mg/m2 in Japanese Patients with Advanced or Recurrent Breast Cancer.
Listeriosis
Crystal Structures of Penicillin-Binding Protein D2 from Listeria monocytogenes and Structural Basis for Antibiotic Specificity.
Liver Cirrhosis
A sample model established by S-index predicting overall survival after curative resection of primary hepatocellular carcinoma.
Liver Cirrhosis
Alanine Aminotransferase Influencing Performances of Routine Available Tests Detecting Hepatitis B Related Cirrhosis.
Liver Cirrhosis
Aspartate aminotransferase to platelet ratio can reduce the need for transient elastography in Chinese patients with chronic hepatitis B.
Liver Cirrhosis
Case-control study on prednisolone combined with ursodeoxycholic acid and azathioprine in pure primary biliary cirrhosis with high levels of immunoglobulin G and transaminases: efficacy and safety analysis.
Liver Cirrhosis
Diagnostic accuracy of the ?-glutamyl transpeptidase to platelet ratio to predict liver fibrosis in Egyptian patients with HCV genotype 4.
Liver Cirrhosis
Efficacy of orlistat in non-alcoholic fatty liver disease: A systematic review and meta-analysis.
Liver Cirrhosis
Interference of diabetes on the association of ?-glutamyl transpeptidase to platelet ratio with liver fibrosis in chronic hepatitis C.
Liver Cirrhosis
Preoperative ?-glutamyl transpeptidase to platelet ratio (GPR) is an independent prognostic factor for HBV-related hepatocellular carcinoma after curative hepatic resection.
Liver Cirrhosis
Preoperative Albumin-Bilirubin Score for Postoperative Solitary Hepatocellular Carcinoma within the Milan Criteria and Child-Pugh A Cirrhosis.
Liver Cirrhosis
The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurements of liver fibrosis in HIV-positive patients with chronic hepatitis B in West Africa. Response to: 'The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa' by Lemoine et al.
Liver Cirrhosis, Alcoholic
[Use of the serum enzymes gamma-glutamyl transpeptidase and pseudocholinesterase in hepatic pathology]
Liver Diseases
A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities.
Liver Diseases
Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis.
Liver Diseases
Association between ratio of ?-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study.
Liver Diseases
Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-?-lowering property.
Liver Diseases
Case of idiopathic portal hypertension complicated with autoimmune hepatitis.
Liver Diseases
Comparative study of CA-50 (time-resolved fluoroimmunoassay), Span-1, and CA19-9 in the diagnosis of pancreatic cancer.
Liver Diseases
Determination of carbohydrate-deficient transferrin levels by using capillary electrophoresis in a Korean population.
Liver Diseases
Effects of periodontal treatment on the medical status of patients with type 2 diabetes mellitus: a pilot study.
Liver Diseases
Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis.
Liver Diseases
Histo- and bio-chemical observations on -glutamyl transpeptidase in liver diseases.
Liver Diseases
Impact of Liver Indicators on Clinical Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation.
Liver Diseases
MicroRNA profiles in serum samples from patients with stable cirrhosis and miRNA-21 as a predictor of transplant-free survival.
Liver Diseases
Nonalcoholic Fatty Liver Disease Is Associated with Increased Atrial Fibrillation Risk in an Elderly Chinese Population: A Cross-Sectional Study.
Liver Diseases
Osteodystrophy in Cholestatic Liver Diseases Is Attenuated by Anti-?-Glutamyl Transpeptidase Antibody.
Liver Diseases
Postoperative Transarterial Chemoembolization Benefits Patients with High ?-Glutamyl Transferase Levels after Curative Hepatectomy for Hepatocellular Carcinoma: A Survival Stratification Analysis.
Liver Diseases
Radioimmunoassay of serum glycocholic acid, standard laboratory tests of liver function and liver biopsy findings: comparative study of children with liver disease.
Liver Diseases
[Gammaglutamyl transpeptidase and other biochemical parameters in the diagnosis of liver disease. Discriminant statistical study]
Liver Diseases
[Practical significance of the serum levels of -glutamyl transpeptidase in various liver diseases]
Liver Diseases
[Prevalence of chronic hepatic disease in Portugal. Apropos of a review carried out in a hepatology unit]
Liver Diseases, Alcoholic
Differential diagnosis, laboratory tests and histology in 245 patients with cholestasis.
Liver Failure
Cholestasis and Hepatic Failure in a Neonate: A Case Report of Severe Pyruvate Kinase Deficiency.
Liver Neoplasms
Change in ?-glutamyl transpeptidase activity as a useful tool in identifying a group of patients with elevated risk of hepatocellular carcinoma development after DAA treatment of chronic hepatitis C.
Liver Neoplasms
Sensitive and selective SERS probe for detecting the activity of ?-glutamyl transpeptidase in serum.
Liver Neoplasms
The effect of caffeic acid phenethyl ester analogues in a modified resistant hepatocyte model.
Lung Injury
Oxygen-induced pulmonary injury in gamma-glutamyl transpeptidase-deficient mice.
Lung Injury
Potentiation of carbon tetrachloride-induced hepatotoxicity and pneumotoxicity by pyridine.
Lung Neoplasms
Antiproliferative and antioxidant potential of beta-ionone against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.
Lung Neoplasms
Development of a Sortase A-mediated Peptide-labeled Liposome Applicable to Drug-delivery Systems.
Lung Neoplasms
Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.
Lymphatic Metastasis
Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma.
Lymphopenia
A Multicenter Study of Docetaxel at a Dose of 100 mg/m2 in Japanese Patients with Advanced or Recurrent Breast Cancer.
Lymphopenia
Additional holmium-166 radioembolisation after lutetium-177-dotatate in patients with neuroendocrine tumour liver metastases (HEPAR PLuS): a single-centre, single-arm, open-label, phase 2 study.
Lymphopenia
Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques.
Meningism
Enzymatic changes in the cerebrospinal fluid in patients with infections of the central nervous system.
Meningitis
Antibiotic susceptibility in relation to penicillin-binding protein genes and serotype distribution of Streptococcus pneumoniae strains responsible for meningitis in Japan, 1999 to 2002.
Meningitis
Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis.
Meningitis
Identification of a patient with Streptococcus pneumoniae bacteremia and meningitis by the polymerase chain reaction (PCR).
Meningitis
Molecular epidemiologic characteristics of Streptococcus pneumoniae isolates from children with meningitis in Japan from 2007 through 2009.
Meningitis, Aseptic
Enzymatic changes in the cerebrospinal fluid in patients with infections of the central nervous system.
Meningitis, Bacterial
Enzymatic changes in the cerebrospinal fluid in patients with infections of the central nervous system.
Meningitis, Bacterial
[An adult case of bacterial meningitis caused by penicillin-resistant Streptococcus pneumoniae with gene mutations of penicillin binding proteins]
Meningomyelocele
Fetal anal incontinence evaluated by amniotic fluid digestive enzyme assay in myelomeningocele spina bifida.
Metabolic Syndrome
?-glutamyl transpeptidase in men and alanine aminotransferase in women are the most suitable parameters among liver function tests for the prediction of metabolic syndrome in nonviral hepatitis and nonfatty liver in the elderly.
Metabolic Syndrome
Association between ratio of ?-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study.
Metabolic Syndrome
Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity.
Metabolic Syndrome
Liver Function Test Changes in Centrally Obese Youth with Metabolic Syndrome in a Serbian Population.
Metabolic Syndrome
The Association of Metabolic Syndrome and Serum ?-Glutamyl Transpeptidase: A 4-Year Cohort Study of 3,698 Korean Male Workers.
Myocardial Infarction
[Biochemical characteristics of uncomplicated and complicated healing of experimental myocardial infarcts]
Myocardial Infarction
[The value of glycine peptidase, leucine aminopeptidase and -glutamyl transpeptidase determinations in distant diagnosis of myocardial infarction]
Myositis
A Single Amino Acid Replacement in Penicillin-Binding Protein 2X in Streptococcus pyogenes Significantly Increases Fitness on Subtherapeutic Benzylpenicillin Treatment in a Mouse Model of Necrotizing Myositis.
Neoplasm Metastasis
Adjuvant Transarterial chemoembolization does not influence recurrence-free or overall survival in patients with combined hepatocellular carcinoma and Cholangiocarcinoma after curative resection: a propensity score matching analysis.
Neoplasm Metastasis
Carcinoembryonic antigen and phosphohexose isomerase, gammaglutamyl transpeptidase and lactate dehydorgenase levels in patients with and without liver metastases.
Neoplasm Metastasis
Histopathology-based immunoscore predicts recurrence for intrahepatic cholangiocarcinoma after hepatectomy.
Neoplasm Metastasis
Inhibition of metastatic lung cancer in C57BL/6 mice by marine mangrove Rhizophora apiculata.
Neoplasm Metastasis
Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma.
Neoplasm Metastasis
[A new screening test in onchology. Gamma-glutamyl transpeptidase in the diagnosis of hepatic metastases]
Neoplasms
?-Glutamyl transpeptidase-activatable near-infrared nanoassembly for tumor fluorescence imaging-guided photothermal therapy.
Neoplasms
?-PGA-Coated Mesoporous Silica Nanoparticles with Covalently Attached Prodrugs for Enhanced Cellular Uptake and Intracellular GSH-Responsive Release.
Neoplasms
A fluorescence-activatable tumor-reporting probe for precise photodynamic therapy.
Neoplasms
A novel mitochondrial-targeting near-infrared fluorescent probe for imaging ?-glutamyl transpeptidase activity in living cells.
Neoplasms
A Novel Pre-treatment Model Predicting Risk of Developing Refractoriness to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma.
Neoplasms
Acceleration of anaerobic cysteine transformations to sulfane sulfur consequent to ?-glutamyl transpeptidase inhibition.
Neoplasms
Activatable Near-Infrared Probe for Fluorescence Imaging of ?-Glutamyl Transpeptidase in Tumor Cells and In Vivo.
Neoplasms
Adjuvant Transarterial chemoembolization does not influence recurrence-free or overall survival in patients with combined hepatocellular carcinoma and Cholangiocarcinoma after curative resection: a propensity score matching analysis.
Neoplasms
Anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.
Neoplasms
Antiproliferative and antioxidant potential of beta-ionone against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.
Neoplasms
Artificial neural network model to predict post-hepatectomy early recurrence of hepatocellular carcinoma without macroscopic vascular invasion.
Neoplasms
Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-?-lowering property.
Neoplasms
Cell-Membrane-Localizing, Two-Photon Probe for Ratiometric Imaging of ?-Glutamyl Transpeptidase in Cancerous Cells and Tissues.
Neoplasms
Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine induced liver tumors and human cancer cell lines.
Neoplasms
Chemoprevention of N-nitrosodiethylamine induced phenobarbitol promoted liver tumors in rat by extract of Indigofera aspalathoides.
Neoplasms
Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.
Neoplasms
Cyclo-?-polyglutamic acid-coated dual-responsive nanomicelles loaded with doxorubicin for synergistic chemo-photodynamic therapy.
Neoplasms
Diabetes mellitus and the neutrophil to lymphocyte ratio predict overall survival in non-viral hepatocellular carcinoma treated with transarterial chemoembolization.
Neoplasms
Differential diagnosis, laboratory tests and histology in 245 patients with cholestasis.
Neoplasms
Effect of radiotherapy on -glutamyl transpeptidase and lactic dehydrogenase activity in cancer of the uterine cervix.
Neoplasms
Elevated serum ?-fetoprotein levels in patients with chronic hepatitis C virus genotype 4: not the end of the story.
Neoplasms
Enzyme-activatable polymer-drug conjugate augments tumour penetration and treatment efficacy.
Neoplasms
Enzyme-Triggered Transcytosis of Dendrimer-Drug Conjugate for Deep Penetration into Pancreatic Tumors.
Neoplasms
Evaluation of metastatic cancer to the eye. Carcinoembryonic antigen and gamma glutamyl transpeptidase.
Neoplasms
Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1.
Neoplasms
Experimental study on anti-tumor and anti-inflammatory effect of Thespesia populnea phytochemical extract in mice models.
Neoplasms
Expression of gamma-glutamyl transpeptidase by renal epithelial cells occurs on a cell-by-cell basis and is inhibited by chronic TPA treatment.
Neoplasms
Fufang Banmao Capsule, a Traditional Chinese Medicinal Formulation, Enhances the Survival of Patients with Hepatocellular Carcinoma and Vp3-4 Portal Vein Tumor Thrombosis Undergoing Supportive Treatment.
Neoplasms
Hepatitis B virus surface antigen-negative and hepatitis C virus antibody-negative hepatocellular carcinoma: Clinical characteristics, outcome, and risk factors for early and late intrahepatic recurrence after resection.
Neoplasms
Histopathology-based immunoscore predicts recurrence for intrahepatic cholangiocarcinoma after hepatectomy.
Neoplasms
In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and intratracheal instillation in rats.
Neoplasms
In vivo tumor imaging by a ?-glutamyl transpeptidase-activatable near-infrared fluorescent probe.
Neoplasms
Independent risk factors for disease recurrence after surgery in patients with hepatitis B virus-related hepatocellular carcinoma ?3 cm in diameter.
Neoplasms
Level of hepatitis B surface antigen might serve as a new marker to predict hepatocellular carcinoma recurrence following curative resection in patients with low viral load.
Neoplasms
Marchantia polymorpha L. Flavonoids Protect Liver From CCl4-Induced Injury by Antioxidant and Gene-Regulatory Effects.
Neoplasms
Nomogram prediction of individual prognosis of patients with hepatocellular carcinoma.
Neoplasms
Potent antitumor and antineoplastic efficacy of baicalein on benzo(a)pyrene-induced experimental pulmonary tumorigenesis.
Neoplasms
Prediction of portal vein invasion by hepatocellular carcinoma: a correlations between portal vein tumor thrombus and biochemical tests.
Neoplasms
Preoperative prediction of microvascular invasion in non-metastatic hepatocellular carcinoma based on nomogram analysis.
Neoplasms
Primary biliary cirrhosis-associated hepatocellular carcinoma in Chinese patients: incidence and risk factors.
Neoplasms
Prognostic predictors for patients with hepatocellular carcinoma receiving adjuvant transcatheter arterial chemoembolization.
Neoplasms
Prognostic Value of Gamma-Glutamyl Transpeptidase to Lymphocyte Count Ratio in Patients With Single Tumor Size ? 5 cm Hepatocellular Carcinoma After Radical Resection.
Neoplasms
Reduction sensitive nanocarriers mPEG-g-?-PGA/SSBPEI@siRNA for effective targeted delivery of survivin siRNA against NSCLC.
Neoplasms
Severe sinusoidal lesions: a serious and overlooked complication of oxaliplatin-containing chemotherapy?
Neoplasms
Single dose intravenous thioacetamide administration as a model of acute liver damage in rats.
Neoplasms
Study to assess Activity and Concentration of Gammaglutamyl Transpeptidase in Precancerous and Cancer Patients and Its Comparison with Controls.
Neoplasms
Surgical tissue handling methods to optimize ex vivo fluorescence with the activatable optical probe ?-glutamyl hydroxymethyl rhodamine green.
Neoplasms
Targeted Delivery of a ?-Glutamyl Transpeptidase Activatable Near-Infrared-Fluorescent Probe for Selective Cancer Imaging.
Neoplasms
The Combination of Age, International Standardized Ratio, Albumin and ?-Glutamyl Transpeptidase (AIAG), Tumor Size and Alpha Fetoprotein (AFP) Stage as the Prognostic Model for Hepatitis B-Related Hepatocellular Carcinoma.
Neoplasms
The Diagnostic and Prognostic Value of Hematological and Chemical Abnormalities in Soft Tissue Sarcoma: A Comparative Study in Patients with Benign and Malignant Soft Tissue Tumors.
Neoplasms
The effect of caffeic acid phenethyl ester analogues in a modified resistant hepatocyte model.
Neoplasms
The Prognostic Value of Systemic Inflammation Response Index in Cholangiocarcinoma Patients.
Neoplasms
[Establishment and biological characteristics of the nude mice xenograft model from human hepatocellular carcinoma]
Neoplasms
[Risk factors of survival for recurrent hepatocellular carcinoma treated by percutaneous radiofrequency ablation].
Neutropenia
A Multicenter Study of Docetaxel at a Dose of 100 mg/m2 in Japanese Patients with Advanced or Recurrent Breast Cancer.
Neutropenia
Brentuximab vedotin for paediatric relapsed or refractory Hodgkin's lymphoma and anaplastic large-cell lymphoma: a multicentre, open-label, phase 1/2 study.
Neutropenia
Phase I/II Study of Radiologic Hepatic Arterial Infusion of Fluorouracil Plus Systemic Irinotecan for Unresectable Hepatic Metastases from Colorectal Cancer: Japan Clinical Oncology Group Trial 0208-DI.
Non-alcoholic Fatty Liver Disease
Association between ratio of ?-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study.
Non-alcoholic Fatty Liver Disease
Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-?-lowering property.
Non-alcoholic Fatty Liver Disease
Comparison of the relationships of alcoholic and nonalcoholic fatty liver with hypertension, diabetes mellitus, and dyslipidemia.
Non-alcoholic Fatty Liver Disease
Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity.
Non-alcoholic Fatty Liver Disease
Favorable effect of sodium-glucose cotransporter 2 inhibitor, dapagliflozin, on non-alcoholic fatty liver disease compared with pioglitazone.
Non-alcoholic Fatty Liver Disease
Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis.
Non-alcoholic Fatty Liver Disease
Improvements in clinical characteristics of patients with non-alcoholic fatty liver disease, after an intervention based on the Mediterranean lifestyle: a randomised controlled clinical trial.
Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease, liver biomarkers and stroke risk: The Reasons for Geographic and Racial Differences in Stroke cohort.
Non-alcoholic Fatty Liver Disease
Nonalcoholic Fatty Liver Disease Is Associated with Increased Atrial Fibrillation Risk in an Elderly Chinese Population: A Cross-Sectional Study.
Non-alcoholic Fatty Liver Disease
Noninvasive estimation of disease activity and liver fibrosis in nonalcoholic fatty liver disease using anthropometric and biochemical characteristics, including insulin, insulin resistance, and 13C-methionine breath test.
Non-alcoholic Fatty Liver Disease
Simple biochemical parameters and a novel score correlate with absence of fibrosis in patients with nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
[Does carbohydrate-deficient transferrin have diagnostic value in non-alcoholic fatty liver disease?]
Obesity
Association between ratio of ?-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study.
Osteolysis
Treatment with anti-gamma-glutamyl transpeptidase antibody attenuates osteolysis in collagen-induced arthritis mice.
Osteoporosis
Osteodystrophy in Cholestatic Liver Diseases Is Attenuated by Anti-?-Glutamyl Transpeptidase Antibody.
Otitis Media
Antimicrobial resistance in Haemophilus influenzae isolated from the nasopharynx among Japanese children with acute otitis media.
Otitis Media
Antimicrobial resistance of Haemophilus influenzae isolated from the nasopharynx of Japanese children with acute otitis media.
Otitis Media
Epidemiology of acute otitis media caused by Streptococcus pneumoniae before and after licensure of the 7-valent pneumococcal protein conjugate vaccine.
Otitis Media
High Prevalence of Streptococcus pneumoniae with Mutations in pbp1a, pbp2x, and pbp2b Genes of Penicillin-Binding Proteins in the Nasopharynx in Children in Japan.
Otitis Media
Nasopharyngeal carriage of drug-resistant Streptococcus pneumoniae in children with acute otitis media evaluated by polymerase chain reaction-based genotyping of penicillin-binding proteins.
Ovarian Neoplasms
Surgical tissue handling methods to optimize ex vivo fluorescence with the activatable optical probe ?-glutamyl hydroxymethyl rhodamine green.
Pancreatic Diseases
Change of serum -glutamyl transpeptidase level and isoenzyme pattern in hepatobiliary pancreatic disease.
Pancreatitis
Brucellosis-related acute pancreatitis: A rare complication of a universal disease.
Pneumococcal Infections
[Serotype distribution and penicillin-binding protein genes of Streptococcus pneumoniae in children with invasive pneumococcal infection]
Pneumonia
Antibiotic susceptibility according to genotype of penicillin-binding protein and macrolide resistance genes, and serotype of Streptococcus pneumoniae isolates from community-acquired pneumonia in children.
Pneumonia
[Novel gene sequence variants of pbp2b in penicillin-nonsusceptible Streptococcus pneumonia isolates]
Proteinuria
Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats.
Pruritus
Phenotypic and Molecular Characteristics of Children with Progressive Familial Intrahepatic Cholestasis in South China.
Pruritus
Predictive ability of shear wave elastography for pruritus in chronic hepatitis C patients with sustained virological response.
Pruritus
[Effects of cyclosporin A on various indices of cholestasis in kidney transplant recipients]
Pseudomonas Infections
Dual ?-lactam combination therapy for multi-drug resistant Pseudomonas aeruginosa infection: enhanced efficacy in vivo and comparison with monotherapies of penicillin-binding protein inhibition.
Psoriasis
Serum Gamma Glutamyl Transpefitidase in Normal Persons and Patients with Psoriasis.
pyruvate kinase deficiency
Cholestasis and Hepatic Failure in a Neonate: A Case Report of Severe Pyruvate Kinase Deficiency.
Reperfusion Injury
Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.
Reperfusion Injury
GGsTop, a novel and specific ?-glutamyl transpeptidase inhibitor, protects hepatic ischemia-reperfusion injury in rats.
Respiratory Tract Infections
?-lactam resistance: The role of low molecular weight penicillin binding proteins, ?-lactamases and ld-transpeptidases in bacteria associated with respiratory tract infections.
Schistosomiasis
[Observation on serum ?-glutamyl transpeptidase levels of patients with subclinical schistosomiasis before and after pathogen treatment].
Sepsis
A streptococcal penicillin-binding protein is critical for resisting innate airway defenses in the neonatal lung.
Sepsis
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase.
Sepsis
Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptides.
Sepsis
Penicillin-binding proteins in Streptococcus agalactiae: a novel mechanism for evasion of immune clearance.
Sepsis
Reduced expression of PBP-2A by neonatal mecA-positive coagulase-negative staphylococci (CoNS) blood isolates: ?-lactams are useful first-line agents for the treatment of neonatal CoNS sepsis, restricting the use of vancomycin.
serine-type d-ala-d-ala carboxypeptidase deficiency
?-glutamyl transpeptidase deficiency caused by a large homozygous intragenic deletion in GGT1.
Soft Tissue Infections
Ceftaroline Is Active against Heteroresistant Methicillin-Resistant Staphylococcus aureus Clinical Strains despite Associated Mutational Mechanisms and Intermediate Levels of Resistance.
Spinal Dysraphism
Fetal anal incontinence evaluated by amniotic fluid digestive enzyme assay in myelomeningocele spina bifida.
Stomach Neoplasms
Role of ?-glutamyl transpeptidase in the pathogenesis of Helicobacter pylori infection.
Stomach Ulcer
Role of ?-glutamyl transpeptidase in the pathogenesis of Helicobacter pylori infection.
Stroke
Non-alcoholic fatty liver disease, liver biomarkers and stroke risk: The Reasons for Geographic and Racial Differences in Stroke cohort.
Stroke
The impact of ischemic preconditioning on hemodynamic, biochemical and inflammatory alterations induced by intra-abdominal hypertension: an experimental study in a porcine model.
Syphilis
A novel beta-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin.
Thrombocytopenia
Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques.
Thrombocytosis
Predictive factors for disease recurrence in patients with locally advanced renal cell carcinoma treated with curative surgery.
Thrombosis
Noncirrhotic Portal Hypertension in HIV-Infected Patients: A Case Control Evaluation and Review of the Literature.
Thrombosis
Predictive factors for disease recurrence in patients with locally advanced renal cell carcinoma treated with curative surgery.
Tricuspid Valve Insufficiency
Prognostic Relevance of Liver Stiffness Assessed by Transient Elastography in Patients With Acute Decompensated Heart Failure.
Tricuspid Valve Insufficiency
Prognostic Value of Prothrombin Time International Normalized Ratio in Acute Decompensated Heart Failure?- A Combined Marker of Hepatic Insufficiency and Hemostatic Abnormality.
Tuberculosis
A Fluorescence-based Assay for Screening ?-Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2.
Tuberculosis
Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis.
Tuberculosis
Characterization of a novel esterase Rv1497 of Mycobacterium tuberculosisH37Rv demonstrating ?-lactamase activity.
Tuberculosis
Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.
Tuberculosis
Deletion and overexpression studies on DacB2, a putative low molecular mass penicillin binding protein from Mycobacterium tuberculosis H(37)Rv.
Tuberculosis
Identification of Mycobacterium tuberculosis signal sequences that direct the export of a leaderless beta-lactamase gene product in Escherichia coli.
Tuberculosis
Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis.
Tuberculosis
Mycobacterium tuberculosis CwsA overproduction modulates cell division and cell wall synthesis.
Tuberculosis
Overexpression, purification and biochemical characterization of a class A high-molecular-mass penicillin-binding protein (PBP), PBP1* and its soluble derivative from Mycobacterium tuberculosis.
Tuberculosis
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis.
Tuberculosis
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.
Tuberculosis
Structures of Mycobacterium tuberculosis Penicillin-Binding Protein 3 in Complex with Five ?-Lactam Antibiotics Reveal Mechanism of Inactivation.
Tuberculosis
Targeting the Mycobacterium tuberculosis transpeptidase LdtMt2 with cysteine-reactive inhibitors including ebselen.
Tuberculosis
The Extended Conformation of the 2.9-Å Crystal Structure of the Three-PASTA Domain of a Ser/Thr Kinase from the Human Pathogen Staphylococcus aureus.
Tuberculosis
The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin.
Tuberculosis
The Role of the ?5-?11 Loop in the Active-Site Dynamics of Acylated Penicillin-Binding Protein A from Mycobacterium tuberculosis.
Tuberculosis
The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division.
Tuberculosis
The transpeptidase PbpA and non-canonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.
Tuberculosis
Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis.
Tuberculosis
[Sequential development of vitamin D metabolites under isoniazid and rifampicin therapy]
Urethritis
Antimicrobial susceptibility and penicillin-binding protein 1 and 2 mutations in Neisseria gonorrhoeae isolated from male urethritis in Sapporo, Japan.
Uterine Cervical Neoplasms
Effect of radiotherapy on -glutamyl transpeptidase and lactic dehydrogenase activity in cancer of the uterine cervix.
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
the crystal structures of native D-amino acid amidase and of the D-phenylalanine/D-amino acid amidase complex are determined at 2.1 and at 2.4 A resolution, respectively
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
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UNIPROT
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Okazaki, S.; Suzuki, A.; Komeda, H.; Yamaguchi, S.; Asano, Y.; Yamane, T.
Crystal structure and functional characterization of a D-stereospecific amino acid amidase from Ochrobactrum anthropi SV3, a new member of the penicillin-recognizing proteins
J. Mol. Biol.
368
79-91
2007
Brucella anthropi (Q9LCC8), Brucella anthropi
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Release 2023.1 (January 2023)
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