Disease on EC 3.4.14.1 - dipeptidyl-peptidase I
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Acro-Osteolysis
New syndrome of hypotrichosis, striate palmoplantar keratoderma, acro-osteolysis and periodontitis not due to mutations in cathepsin C.
Adenocarcinoma
Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus.
Adenocarcinoma
[Modern esophageal surgery and late functional results as equations with several unknowns--Hungarian Academy of Sciences Doctoral Thesis]
Adenocarcinoma of Lung
Cysteine proteases and cysteine protease inhibitors in non-small cell lung cancer.
Aggressive Periodontitis
Cathepsin C gene 5'-untranslated region mutation in papillon-lefèvre syndrome.
Aggressive Periodontitis
Confirmation of oxidative stress and fatty acid disturbances in two further Papillon-Lefèvre syndrome families with identification of a new mutation.
Aggressive Periodontitis
Dermatologic, periodontal, and skeletal manifestations of Haim-Munk syndrome in two siblings.
Aggressive Periodontitis
Functional Cathepsin C mutations cause different Papillon-Lefèvre syndrome phenotypes.
Aggressive Periodontitis
Identification of cathepsin C mutations in ethnically diverse papillon-Lefèvre syndrome patients.
Aggressive Periodontitis
Identification of genetic risk factors for periodontitis and possible mechanisms of action.
Aggressive Periodontitis
Localisation of a gene for prepubertal periodontitis to chromosome 11q14 and identification of a cathepsin C gene mutation.
Aggressive Periodontitis
Mutations of the cathepsin C gene are responsible for Papillon-Lefèvre syndrome.
Aggressive Periodontitis
Novel mutations in the cathepsin C gene in patients with pre-pubertal aggressive periodontitis and Papillon-Lefèvre syndrome.
Aggressive Periodontitis
The role of cathepsin C in Papillon-Lefèvre syndrome, prepubertal periodontitis, and aggressive periodontitis.
Anaphylaxis
Biomarkers in Human Anaphylaxis: A Critical Appraisal of Current Evidence and Perspectives.
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
The Synthesis of ?,?-Disubstituted ?-Amino Acids via Ichikawa Rearrangement.
Aortic Aneurysm, Abdominal
Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms.
Aortic Aneurysm, Abdominal
Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation.
Aortic Aneurysm, Abdominal
Role of cathepsin C in elastase-induced mouse abdominal aortic aneurysms.
Arrhythmias, Cardiac
Electrophysiological and Anatomical Correlates of Sites With Postpacing Intervals Shorter Than Tachycardia Cycle Length in Atypical Atrial Flutter.
Arthritis
Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis.
Arthritis
Liposomes encapsulated dimethyl curcumin regulates dipeptidyl peptidase I activity, gelatinase release and cell cycle of spleen lymphocytes in-vivo to attenuate collagen induced arthritis in rats.
Arthritis
Serum based fluorescent assay for evaluating dipeptidyl peptidase I activity in collagen induced arthritis rat model.
Arthritis, Experimental
Dipeptidyl peptidase I regulates the development of collagen-induced arthritis.
Arthritis, Experimental
Serum based fluorescent assay for evaluating dipeptidyl peptidase I activity in collagen induced arthritis rat model.
Arthritis, Rheumatoid
The regulatory role of Dipeptidyl peptidase I on the activation of immune granulocytes.
Aspergillosis
Antifungal Treatments Delineate a Correlation between Cathepsins and Cytokines in Murine Model of Invasive Aspergillosis.
Asthma
Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways.
Asthma
Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to sendai virus infection.
Asthma
Identification of an alternative splicing variant of cathepsin C/dipeptidyl-peptidase I.
Asthma
Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype.
Atherosclerosis
Leukocyte cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses.
Atrial Flutter
Electrophysiological and Anatomical Correlates of Sites With Postpacing Intervals Shorter Than Tachycardia Cycle Length in Atypical Atrial Flutter.
Autoimmune Diseases
Development of potent and selective Cathepsin C inhibitors free of aortic binding liability by application of a conformational restriction strategy.
Autoimmune Diseases
Identification and Optimization of Novel Cathepsin C Inhibitors Derived from EGFR Inhibitors.
Blister
Acid hydrolases in blister fluid. 3. Characterization and quantification of peptide hydrolases.
Breast Neoplasms
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
Bronchiectasis
Cathepsin C inhibitors as anti-inflammatory drug discovery: Challenges and opportunities.
Bronchiectasis
The Synthesis of ?,?-Disubstituted ?-Amino Acids via Ichikawa Rearrangement.
Carcinoma
Cysteine proteases and cysteine protease inhibitors in non-small cell lung cancer.
Carcinoma
Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma.
Carcinoma
Lysosomal dipeptidyl-peptidases I and II in human squamous cell lung carcinoma and lung parenchyma.
Carcinoma, Hepatocellular
Cathepsin C Interacts with TNF-?/p38 MAPK Signaling Pathway to Promote Proliferation and Metastasis in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Synthesis, transport and processing of cathepsin C in Morris hepatoma 7777 cells and rat hepatocytes.
Carcinoma, Renal Cell
Timosaponin AIII inhibits metastasis of renal carcinoma cells through suppressing cathepsin C expression by AKT/miR-129-5p axis.
Carcinoma, Squamous Cell
Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma.
cathepsin l deficiency
Epidermal differentiation: the role of proteases and their inhibitors.
Cholesteatoma
Gene expression analysis of human middle ear cholesteatoma using complementary DNA arrays.
Colonic Neoplasms
Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2.
Colorectal Neoplasms
In vitro and in vivo studies on potentiation of curcumin-induced lysosomal-dependent apoptosis upon silencing of cathepsin C in colorectal cancer cells.
Colorectal Neoplasms
Targeting of cathepsin C induces autophagic dysregulation that directs ER stress mediated cellular cytotoxicity in colorectal cancer cells.
Coronary Artery Disease
Digital arterial pressure pulse wave analysis and cardiovascular events in the general population: the Prevention of Renal and Vascular End-stage Disease study.
COVID-19
Cathepsin C inhibitors as anti-inflammatory drug discovery: Challenges and opportunities.
Cystic Fibrosis
The Synthesis of ?,?-Disubstituted ?-Amino Acids via Ichikawa Rearrangement.
Cysts
The activity of a developmentally regulated cysteine proteinase is required for cyst wall formation in the primitive eukaryote Giardia lamblia.
Demyelinating Diseases
Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.
Demyelinating Diseases
Correction: Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model.
Demyelinating Diseases
Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model.
Demyelinating Diseases
The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.
Diabetes Mellitus
Inflammatory Serine Proteases Play a Critical Role in the Early Pathogenesis of Diabetic Cardiomyopathy.
Diabetes Mellitus, Type 1
Inflammatory Serine Proteases Play a Critical Role in the Early Pathogenesis of Diabetic Cardiomyopathy.
dipeptidyl-peptidase i deficiency
Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants.
dipeptidyl-peptidase i deficiency
Characterization of neutrophil function in Papillon-Lefèvre syndrome.
dipeptidyl-peptidase i deficiency
Leukocyte cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses.
dipeptidyl-peptidase i deficiency
Nemaline myopathy. Evidence of dipeptidyl peptidase I deficiency.
dipeptidyl-peptidase i deficiency
NSP4 Is Stored in Azurophil Granules and Released by Activated Neutrophils as Active Endoprotease with Restricted Specificity.
dipeptidyl-peptidase i deficiency
Papillon-Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans.
dipeptidyl-peptidase i deficiency
Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.
dipeptidyl-peptidase i deficiency
Structure of the periodontium in cathepsin C-deficient mice.
Ectodermal Dysplasia
Diagnosis of Papillon-Lefèvre syndrome: review of the literature and a case report.
Ectromelia
Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.
Encephalomyelitis
Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.
Enteritis
Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.
Enterocolitis, Necrotizing
Human breast milk oligosaccharides attenuate necrotizing enterocolitis in rats by suppressing mast cell accumulation, DPPI activity and TLR4 expression in ileum tissue, and regulating mitochondrial damage of Caco-2 cells.
Genetic Diseases, Inborn
Cu-sil dentures: A novel approach of Papillon-Lefèvre syndrome management.
Gingivitis
A novel mutation in the cathepsin C gene in a Pakistani family with Papillon-Lefevre syndrome.
Glioma
Intravascular streaming during carotid artery infusions. Demonstration in humans and reduction using diastole-phased pulsatile administration.
Glomerulonephritis, Membranous
Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis.
Granulomatosis with Polyangiitis
Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).
Heart Failure
Digital arterial pressure pulse wave analysis and cardiovascular events in the general population: the Prevention of Renal and Vascular End-stage Disease study.
Hyperglycemia
Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia.
Hypertension
Hydrolase activities in the rat aorta. II. Effects of hypertension alone and in combination with diabetes mellitus.
Hypotrichosis
New syndrome of hypotrichosis, striate palmoplantar keratoderma, acro-osteolysis and periodontitis not due to mutations in cathepsin C.
Infections
Abrogation of cathepsin C by Helicobacter pylori impairs neutrophil activation to promote gastric infection.
Infections
Cathepsin Cs are key for the intracellular survival of the protozoan parasite, Toxoplasma gondii.
Infections
Characterization of cathepsin C from orange-spotted grouper, Epinephelus coioides involved in SGIV infection.
Infections
Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D.
Infections
Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis.
Joint Diseases
Serum based fluorescent assay for evaluating dipeptidyl peptidase I activity in collagen induced arthritis rat model.
Keratoderma, Palmoplantar
A novel mutation in the cathepsin C gene in a Pakistani family with Papillon-Lefevre syndrome.
Keratoderma, Palmoplantar
Cathepsin C gene 5'-untranslated region mutation in papillon-lefèvre syndrome.
Keratoderma, Palmoplantar
Cathepsin C gene: First compound heterozygous patient with Papillon-Lefèvre syndrome and a novel symptomless mutation.
Keratoderma, Palmoplantar
Demonstration of altered splicing with the IVS3-1G --> a mutation of cathepsin C.
Keratoderma, Palmoplantar
Identification of a novel cathepsin C mutation (p.W185X) in a Brazilian kindred with Papillon-Lefèvre syndrome.
Keratoderma, Palmoplantar
Identification of cathepsin C mutations in ethnically diverse papillon-Lefèvre syndrome patients.
Keratoderma, Palmoplantar
Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis.
Keratoderma, Palmoplantar
New syndrome of hypotrichosis, striate palmoplantar keratoderma, acro-osteolysis and periodontitis not due to mutations in cathepsin C.
Keratoderma, Palmoplantar
Papillon-Lefèvre syndrome (PLS) with novel compound heterozygous mutation in the exclusion and Peptidase C1A domains of Cathepsin C gene.
Keratoderma, Palmoplantar
The role of cathepsin C in Papillon-Lefèvre syndrome, prepubertal periodontitis, and aggressive periodontitis.
Keratosis
Confirmation of oxidative stress and fatty acid disturbances in two further Papillon-Lefèvre syndrome families with identification of a new mutation.
Liver Diseases
[Characteristics of bleeding from esophageal-gastric varices in patients with HIV infection]
Liver Neoplasms, Experimental
Synthesis, transport and processing of cathepsin C in Morris hepatoma 7777 cells and rat hepatocytes.
Liver Neoplasms, Experimental
Transient membrane association of the precursors of cathepsin C during their transfer into lysosomes.
Lung Diseases
Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways.
Lung Diseases
Neutrophilic cathepsin C is maturated by a multi-step proteolytic process and secreted by activated cells during inflammatory lung diseases.
Lymphatic Metastasis
Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus.
Malaria
Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I using small molecule inhibitors and active site probes.
Malaria
Plasmodium dipeptidyl aminopeptidases as malaria transmission-blocking drug targets.
Mastocytoma
Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I.
Mastocytoma
Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I.
Muscular Dystrophies
Decreased lysosomal dipeptidyl aminopeptidase I activity in cultured human skin fibroblasts in Duchenne's muscular dystrophy.
Muscular Dystrophy, Duchenne
Dipeptidyl peptidase I in cultured fibroblasts in Duchenne muscular dystrophy.
Myocardial Infarction
Meta-Analysis of the Cardiovascular Outcomes with Dipeptidyl Peptidase 4 Inhibitors: Validation of the Current FDA Mandate.
Neoplasm Metastasis
Cathepsin C Interacts with TNF-?/p38 MAPK Signaling Pathway to Promote Proliferation and Metastasis in Hepatocellular Carcinoma.
Neoplasm Metastasis
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
Neoplasm Metastasis
Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus.
Neoplasm Metastasis
Timosaponin AIII inhibits metastasis of renal carcinoma cells through suppressing cathepsin C expression by AKT/miR-129-5p axis.
Neoplasms
Cathepsin C Interacts with TNF-?/p38 MAPK Signaling Pathway to Promote Proliferation and Metastasis in Hepatocellular Carcinoma.
Neoplasms
Demonstration of proteases in basal cell carcinomas. A histochemical study using amino acid-4-methoxy-2-naphthylamides as chromogenic substrates.
Neoplasms
Expression of the interleukin-4 receptor alpha in human conjunctival epithelial cells.
Neoplasms
Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus.
Neoplasms
Simultaneous expression of Cathepsins B and K in pulmonary adenocarcinomas and squamous cell carcinomas predicts poor recurrence-free and overall survival.
Neoplasms
Spectrum of toxicities of amino acid methyl esters for myeloid cells is determined by distinct metabolic pathways.
Neoplasms
Targeting of cathepsin C induces autophagic dysregulation that directs ER stress mediated cellular cytotoxicity in colorectal cancer cells.
Neoplasms
The production of tumour necrosis factor, tissue thromboplastin, lactoferrin and cathepsin C during lipopolysaccharide stimulation in whole blood.
Neoplasms
[Modern esophageal surgery and late functional results as equations with several unknowns--Hungarian Academy of Sciences Doctoral Thesis]
Nephritis, Interstitial
Identification and characterization of the interactive proteins with cytotoxic T-lymphocyte antigen-2?
Nephrosis, Lipoid
Proteomic Analysis Identifies Distinct Glomerular Extracellular Matrix in Collapsing Focal Segmental Glomerulosclerosis.
Nervous System Diseases
Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model.
Neurodegenerative Diseases
Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis.
Neuroinflammatory Diseases
Cathepsin C Aggravates Neuroinflammation Involved in Disturbances of Behaviour and Neurochemistry in Acute and Chronic Stress-Induced Murine Model of Depression.
Neuroinflammatory Diseases
Cathepsin C aggravates neuroinflammation via promoting production of CCL2 and CXCL2 in glial cells and neurons in a cryogenic brain lesion.
Neuroinflammatory Diseases
Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-?B pathway.
Neuroinflammatory Diseases
Correction to: Cathepsin C Aggravates Neuroinflammation Involved in Disturbances of Behaviour and Neurochemistry in Acute and Chronic Stress-Induced Murine Model of Depression.
Neuroinflammatory Diseases
Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation.
Neuronal Ceroid-Lipofuscinoses
Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis.
Pancreatic Neoplasms
The iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targets.
Pancreatitis
Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin.
Papillon-Lefevre Disease
A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity.
Papillon-Lefevre Disease
A homozygous cathepsin C mutation associated with Haim-Munk syndrome.
Papillon-Lefevre Disease
A novel mutation in the cathepsin C (CTSC) gene in Iranian family with Papillon-Lefevre syndrome.
Papillon-Lefevre Disease
A novel mutation in the cathepsin C gene in a Pakistani family with Papillon-Lefevre syndrome.
Papillon-Lefevre Disease
A novel mutation of the cathepsin C gene in a thai family with Papillon-Lefevre syndrome.
Papillon-Lefevre Disease
Cathepsin C involvement in the aetiology of Papillon-Lefevre syndrome.
Papillon-Lefevre Disease
Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.
Papillon-Lefevre Disease
Epidermal differentiation: the role of proteases and their inhibitors.
Papillon-Lefevre Disease
Papillon-Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans.
Papillon-Lefevre Disease
Papillon-Lefèvre syndrome (PLS) with novel compound heterozygous mutation in the exclusion and Peptidase C1A domains of Cathepsin C gene.
Papillon-Lefevre Disease
Papillon-Lefevre syndrome (PLS) without cathepsin C mutation: A rare early onset partially penetrant variant of PLS.
Papillon-Lefevre Disease
Whole-exome sequencing reveals a recurrent mutation in the cathepsin C gene that causes Papillon-Lefevre syndrome in a Saudi family.
Papillon-Lefevre Disease
[Mutational analysis of the cathepsin C gene in a family of Han nationality with Papillon-Lefevre syndrome.]
Paralysis
Proteolytic enzymes in ordinary, hyperacute, monocytic and passive transfer forms of experimental allergic encephalomyelitis.
Pemphigoid, Bullous
Dipeptidyl peptidase-4 inhibitors and bullous pemphigoid: A systematic review and adjusted meta-analysis.
Periodontal Diseases
Are proteinase 3 and cathepsin C enzymes related to pathogenesis of periodontitis?
Periodontal Diseases
Cathepsin C gene: First compound heterozygous patient with Papillon-Lefèvre syndrome and a novel symptomless mutation.
Periodontal Diseases
Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis.
Periodontal Diseases
Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis.
Periodontal Diseases
Mutations of the cathepsin C gene are responsible for Papillon-Lefèvre syndrome.
Periodontitis
Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.
Periodontitis
Identification of cathepsin C mutations in ethnically diverse papillon-Lefèvre syndrome patients.
Periodontitis
Identification of putative genetic modifying factors that influence the development of Papillon-Lefévre or Haim-Munk syndrome phenotypes.
Periodontitis
Mutation analysis of cathepsin C gene in a Chinese patient with pre-pubertal periodontitis.
Periodontitis
Mutations of the cathepsin C gene are responsible for Papillon-Lefèvre syndrome.
Periodontitis
New syndrome of hypotrichosis, striate palmoplantar keratoderma, acro-osteolysis and periodontitis not due to mutations in cathepsin C.
Periodontitis
Papillon-Lefèvre syndrome (PLS) with novel compound heterozygous mutation in the exclusion and Peptidase C1A domains of Cathepsin C gene.
Periodontitis
Papillon-Lefèvre Syndrome with Homozygous Nonsense Mutation of Cathepsin C Gene Presenting with Late-Onset Periodontitis.
Periodontitis
Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre.
Periodontitis
Role of polymorphonuclear leukocyte-derived serine proteinases in defense against Actinobacillus actinomycetemcomitans.
Periodontitis
The role of cathepsin C in Papillon-Lefèvre syndrome, prepubertal periodontitis, and aggressive periodontitis.
Peritonitis
Dipeptidyl peptidase I controls survival from Klebsiella pneumoniae lung infection by processing surfactant protein D.
Pre-Eclampsia
Upregulation of cathepsin C expression contributes to endothelial chymase activation in preeclampsia.
Primary Graft Dysfunction
Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.
Proteinuria
[Peptidases in the kidney of male rats following castration and testosterone substitution]
Pulmonary Disease, Chronic Obstructive
Development of potent and selective Cathepsin C inhibitors free of aortic binding liability by application of a conformational restriction strategy.
Pulmonary Disease, Chronic Obstructive
Discovery and In Vivo Anti-inflammatory Activity Evaluation of a Novel Non-peptidyl Non-covalent Cathepsin C Inhibitor.
Respiratory Distress Syndrome
Development of potent and selective Cathepsin C inhibitors free of aortic binding liability by application of a conformational restriction strategy.
Squamous Cell Carcinoma of Head and Neck
Expression of angiopoietin-like 4 and tenascin C but not cathepsin C mRNA predicts prognosis of oral tongue squamous cell carcinoma.
Stomach Neoplasms
Decursin inhibits cell growth and autophagic flux in gastric cancer via suppression of cathepsin C.
Stroke
Meta-Analysis of the Cardiovascular Outcomes with Dipeptidyl Peptidase 4 Inhibitors: Validation of the Current FDA Mandate.
Toxoplasmosis
Cathepsin Cs are key for the intracellular survival of the protozoan parasite, Toxoplasma gondii.
Toxoplasmosis
DNA Vaccines Encoding Toxoplasma gondii Cathepsin C 1 Induce Protection against Toxoplasmosis in Mice.
Vasculitis
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
Virus Diseases
Cathepsin C limits acute viral infection independently of NK cell and CD8(+) T-cell cytolytic function.
Virus Diseases
Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to sendai virus infection.
Virus Diseases
Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.
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