Disease on EC 3.3.2.9 - microsomal epoxide hydrolase

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking.
Microsomal epoxide hydrolase polymorphism and risk of spontaneous abortion.
Abruptio Placentae
Low-activity haplotype of the microsomal epoxide hydrolase gene is protective against placental abruption.
Adenocarcinoma
Associations between genetic polymorphisms of Phase I and II metabolizing enzymes, p53 and susceptibility to esophageal adenocarcinoma.
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Adenoma
A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferase M3, and risk of colorectal adenomas.
Colorectal polyp type and the association with charred meat consumption, smoking, and microsomal epoxide hydrolase polymorphisms.
Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study.
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk.
Adrenocortical Carcinoma
Levels of cytochrome P-450, steroidogenesis and microsomal and cytosolic epoxide hydrolases in normal human adrenal tissue and corresponding tumors.
Alzheimer Disease
Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin.
Anemia, Aplastic
Genetic polymorphisms of glutathione-S-transferase and microsomal epoxide hydrolase in egyptian acquired aplastic anemia patients.
The clinical relevance and prognostic significance of microsomal epoxide hydrolase gene polymorphisms and their susceptibility to acquired aplastic anemia: an Egyptian study.
Anthracosis
[Gene variance in microsomal epoxide hydrolase and the susceptibility of coal workers' pneumoconiosis].
Asthma
EPHX1 polymorphisms, COPD and asthma in 47,000 individuals and in meta-analysis.
Genetic architecture of transcript-level variation in humans.
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.
Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility.
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.
Interactions between polycyclic aromatic hydrocarbons and epoxide hydrolase 1 play roles in asthma.
Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma.
Microsomal epoxide hydroxylase genotypes/diplotypes, traffic air pollution, and childhood asthma.
Bone Diseases
Genetic polymorphisms of EPHX1, Gsk3beta, TNFSF8 and myeloma cell DKK-1 expression linked to bone disease in myeloma.
Brain Neoplasms
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Identification of the putative brain tumor antigen BF7/GE2 as the (de)toxifying enzyme microsomal epoxide hydrolase.
Investigation of the Association between Genetic Polymorphism of Microsomal Epoxide Hydrolase and Primary Brain Tumor Incidence.
Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors.
Breast Neoplasms
A systematic approach to analysing gene-gene interactions: polymorphisms at the microsomal epoxide hydrolase EPHX and glutathione S-transferase GSTM1, GSTT1, and GSTP1 loci and breast cancer risk.
An Introduction to the Performance of Immunohistochemistry.
Breast cancer: role of polymorphisms in biotransformation enzymes.
Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies.
Implication of Xenobiotic Metabolizing Enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma.
Meta-analysis of microsomal epoxide hydrolase gene polymorphism and the risk of breast carcinoma.
Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: a retrospective exploratory study with long-term follow-up.
Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle.
Microsomal epoxide hydrolase variants are not associated with risk of breast cancer.
Quantitative assessment of the effects of the EPHX1 Tyr113His polymorphism on lung and breast cancer.
Time and dose-dependent modulation of phase 1 and phase 2 gene expression in response to treatment of MCF-7 cells with a natural anti-cancer agent.
Try113His and His139Arg polymorphisms in the microsomal epoxide hydrolase gene are not associated with risk of breast cancer.
Bronchitis
Air pollution and childhood bronchitis: Interaction with xenobiotic, immune regulatory and DNA repair genes.
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Bronchitis, Chronic
Genetic polymorphisms in the cytochromes P-450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children.
Carcinogenesis
Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking.
Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan.
Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.
EPHX1 polymorphisms and the risk of lung cancer: a HuGE review.
Expression of rat microsomal epoxide hydrolase gene during liver chemical carcinogenesis.
Genetic polymorphisms of smoking-related carcinogen detoxifying enzymes and head and neck cancer susceptibility.
Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of C-Jun N-terminal kinase and its extracellular exposure during cell death.
Lack of association of EPHX1 gene polymorphisms with risk of hepatocellular carcinoma: a meta-analysis.
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence.
Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.
Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: The Fukuoka Colorectal Cancer Study.
Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice.
Polymorphisms of xenobiotic metabolizing genes in oropharyngeal carcinoma.
Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers: A Comprehensive Meta-Analysis.
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene.
The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis.
Weighted gene co-expression network analysis of pneumocytes under exposure to a carcinogenic dose of chloroprene.
[A study on the inherited susceptibility of chromosomal damage in peripheral blood lymphocytes among coke oven workers]
[Functional analysis of drug metabolizing enzymes using gene knockout animals]
[The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer]
Carcinoma
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China.
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Epoxide hydrolase Tyr113His polymorphism is not associated with susceptibility to esophageal squamous cell carcinoma in population of North China.
Levels of cytochrome P-450, steroidogenesis and microsomal and cytosolic epoxide hydrolases in normal human adrenal tissue and corresponding tumors.
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence.
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Microsomal epoxide hydrolase and glutathione S-transferase polymorphisms in relation to laryngeal carcinoma risk.
Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.
Polymorphisms in metabolizing enzymes and the risk of head and neck squamous cell carcinoma in the Slavic population of the central Europe.
Polymorphisms of xenobiotic metabolizing genes in oropharyngeal carcinoma.
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Carcinoma, Hepatocellular
Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase.
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
Epoxide hydrolase: a marker for experimental hepatocarcinogenesis.
Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India.
Haplotypes of Microsomal Epoxide Hydrolase and X-Ray Cross-Complementing Group 1 Genes in Indian Hepatocellular Carcinoma Patients.
Hepatic transcriptional up-regulator of the rat microsomal epoxide hydrolase gene.
Immunochemical comparison of human and rhesus monkey liver microsomal and the hepatocellular carcinoma-induced human serum epoxide hydrolases (preneoplastic antigens): basis for an enzyme-linked immunoabsorbent assay.
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Induction of epoxide hydrolase in cultured rat hepatocytes and hepatoma cell lines.
Lack of association of EPHX1 gene polymorphisms with risk of hepatocellular carcinoma: a meta-analysis.
Meta-analysis of microsomal epoxide hydrolase gene polymorphism and risk of hepatocellular carcinoma.
Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population.
Regulation of microsomal, xenobiotic epoxide hydrolase messenger RNA in persistent hepatocyte nodules and hepatomas induced by chemical carcinogens.
Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics.
Role of genetic polymorphism of glutathione-S-transferase T1 and microsomal epoxide hydrolase in aflatoxin-associated hepatocellular carcinoma.
The expression of cytochrome P-450, epoxide hydrolase, and glutathione S-transferase in hepatocellular carcinoma.
[Enzymes metabolizing xenobiotics in spontaneous tumors in mice]
[EPHX1 Tyr113His polymorphism contributes to hepatocellular carcinoma risk: evidfnce from a meta-analysis].
[Purification of human microsomal epoxide hydrolase and study on its localization in hepatocellular carcinoma tissue]
Carcinoma, Intraductal, Noninfiltrating
Increased Breast Density Correlates with the Proliferation-Seeking Radiotracer (99m)Tc(V)-DMSA Uptake in Florid Epithelial Hyperplasia and in Mixed Ductal Carcinoma In Situ with Invasive Ductal Carcinoma but Not in Pure Invasive Ductal Carcinoma or in Mild Epithelial Hyperplasia.
Carcinoma, Non-Small-Cell Lung
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer.
Carcinoma, Ovarian Epithelial
Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk.
[Relation Between microsomal epoxide hydrolase polymorphism and susceptibility to ovarian epithelial cancer]
Carcinoma, Squamous Cell
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.
Polymorphisms in metabolizing enzymes and the risk of head and neck squamous cell carcinoma in the Slavic population of the central Europe.
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
Cardiovascular Diseases
eNOSI4 and EPHX1 polymorphisms affect maternal susceptibility to preeclampsia: analysis of five polymorphisms predisposing to cardiovascular disease in 279 Caucasian and 241 African women.
Cataract
Glaucoma following congenital cataract surgery--the role of early surgery and posterior capsulotomy.
Colonic Neoplasms
Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer.
Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk.
Colorectal Neoplasms
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.
Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome.
Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis.
Investigation of a Possible Relationship Between EPHX1 Gene Polymorphisms and Colorectal Cancer in Turkish Society.
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: The Fukuoka Colorectal Cancer Study.
Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
NQO1 and mEH exon 4 (mEH4) gene polymorphisms, smoking and colorectal cancer risk.
Systematic Review and Meta-Analysis of the Relationship between EPHX1 Polymorphisms and Colorectal Cancer Risk.
Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer.
Colorectal Neoplasms, Hereditary Nonpolyposis
Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome.
Congenital Abnormalities
Application of kinetic polymerase chain reaction and molecular beacon assays to pooled analyses and high-throughput genotyping for candidate genes.
Differences in phenytoin biotransformation and susceptibility to congenital malformations: a review.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
The Tyr113His polymorphism in exon 3 of the microsomal epoxide hydrolase gene is a risk factor for perinatal mortality.
Craniofacial Abnormalities
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.
Crohn Disease
Genetic association between EPHX1 and Crohn's disease: population stratification, genotyping error, or random chance?
Genetic polymorphisms in biotransformation enzymes in Crohn's disease: association with microsomal epoxide hydrolase.
No genetic association between EPHX1 and Crohn's disease.
Cystic Fibrosis
Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency.
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Dehydration
Heterocyclic polycyclic aromatic hydrocarbon carcinogenesis: 7H-dibenzo[c,g]carbazole metabolism by microsomal enzymes from mouse and rat liver.
Diabetes Mellitus
Possible role of microsomal epoxide hydrolase gene polymorphism as a risk factor for developing insulin resistance and type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Possible role of microsomal epoxide hydrolase gene polymorphism as a risk factor for developing insulin resistance and type 2 diabetes mellitus.
DNA Repair-Deficiency Disorders
Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia.
Drug-Related Side Effects and Adverse Reactions
Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions.
Endometriosis
The association of endometriosis risk and genetic polymorphisms involving dioxin detoxification enzymes: A systematic review.
Epilepsy
Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy.
Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population.
Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients.
Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy.
Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.
In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide.
Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformations.
Esophageal Neoplasms
Association between esophageal cancer risk and EPHX1 polymorphisms: a meta-analysis.
Association between microsomal epoxide hydrolase 1 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.
CYP1A1, GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma: study of population from a high- incidence area in north China.
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
EPHX1 Tyr113His and His139Arg polymorphisms in esophageal cancer risk: a meta-analysis.
Lack of association between EPHX1 polymorphism and esophageal cancer risk: evidence from meta-analysis.
Meta-analysis demonstrates lack of an association of microsomal epoxide hydrolase 1 polymorphisms with esophageal cancer risk.
Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer.
Role of epoxide hydrolase 1 gene polymorphisms in esophageal cancer in a high-risk area in India.
[Spermidine radioimmunoassay in monitor of precancerous lesions of esophagus]
Esophageal Squamous Cell Carcinoma
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.
EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.
Epoxide hydrolase Tyr113His polymorphism is not associated with susceptibility to esophageal squamous cell carcinoma in population of North China.
Gastroesophageal Reflux
Genetic polymorphisms of microsomal epoxide hydroxylase and glutathione S-transferases M1, T1 and P1, interactions with smoking, and risk for esophageal (Barrett) adenocarcinoma.
Glaucoma
The quality of optometrists' referral letters for glaucoma.
Glioblastoma
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Glioma
Identification of the putative brain tumor antigen BF7/GE2 as the (de)toxifying enzyme microsomal epoxide hydrolase.
Head and Neck Neoplasms
Association between head and neck cancer and microsomal epoxide hydrolase genotypes.
CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer.
Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.
Systematic Review and Meta-Analysis of the Relationship between EPHX1 Polymorphisms and the Risk of Head and Neck Cancer.
Heart Diseases
The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure.
Hepatitis
Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians.
Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India.
Haplotypes of Microsomal Epoxide Hydrolase and X-Ray Cross-Complementing Group 1 Genes in Indian Hepatocellular Carcinoma Patients.
Hepatitis A
Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A.
Hepatitis B
Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity.
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Hepatitis C
Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A.
Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians.
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
The levels of monoamine neurotransmitters and measures of mental and emotional health in HCV patients treated with ledipasvir (LDV) and sofosbuvir (SOF) with or without ribavirin (RBV).
Hyperlipidemias
Effects of poloxamer 407-induced hyperlipidemia on the pharmacokinetics of carbamazepine and its 10,11-epoxide metabolite in rats: Impact of decreased expression of both CYP3A1/2 and microsomal epoxide hydrolase.
Hypersensitivity
Genetic analysis of microsomal epoxide hydrolase in patients with carbamazepine hypersensitivity.
Kinetic parameters of lymphocyte microsomal epoxide hydrolase in carbamazepine hypersensitive patients. Assessment by radiometric HPLC.
Hypertension
Clinical features of end-stage renal failure in patients with essential hypertension.
Hyperthyroidism
Thyroid hormone-induced changes in the hepatic monooxygenase system, heme oxygenase activity and epoxide hydrolase activity in adult male, female and immature rats.
Infections
Fasciola hepatica: liver microsomal membrane functions in host rat.
Human papillomavirus 13 in a Mexican Mayan community with multifocal epithelial hyperplasia: could saliva be involved in household transmission?
Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection.
Susceptibility to Helicobacter pylori infection: results of an epidemiological investigation among gastric cancer patients.
Infertility, Male
Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe Oligozoospermia.
Inflammatory Bowel Diseases
Common polymorphisms in the microsomal epoxide hydrolase and N-acetyltransferase 2 genes in association with inflammatory bowel disease in the Danish population.
Insulin Resistance
Possible role of microsomal epoxide hydrolase gene polymorphism as a risk factor for developing insulin resistance and type 2 diabetes mellitus.
Intussusception
Myoepithelial hamartoma causing small-bowel intussusception: a case report and literature review.
Laryngeal Neoplasms
Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.
High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.
Microsomal epoxide hydrolase and glutathione S-transferase polymorphisms in relation to laryngeal carcinoma risk.
Leishmaniasis
Changes in hepatic xenobiotic-metabolising enzymes in mouse liver following infection with Leishmania donovani.
Leukemia
Analysis of the characteristics and expression profiles of coding and noncoding RNAs of human dental pulp stem cells in hypoxic conditions.
Emerging role of EPHX1 in chemoresistance of acute myeloid leukemia by regurlating drug-metabolizing enzymes and apoptotic signaling.
Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity.
Leukemia, Myeloid, Acute
Association of Glutathione S-Transferase, EPHX, and p53 codon 72 Gene Polymorphisms with Adult Acute Myeloid Leukemia.
Emerging role of EPHX1 in chemoresistance of acute myeloid leukemia by regurlating drug-metabolizing enzymes and apoptotic signaling.
EPHX1 rs1051740 T>C (Tyr113His) is strongly associated with acute myeloid leukemia and KMT2A rearrangements in early age.
Liver Cirrhosis
[Psychometric hepatic encephalopathy score normalization data for the Portuguese population].
Liver Cirrhosis, Alcoholic
The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver.
Liver Diseases
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Polymorphisms of microsomal epoxide hydrolase gene and severity of HCV-related liver disease.
Liver Diseases, Alcoholic
Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population.
Liver Neoplasms
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Lung Diseases
Microsomal epoxide hydrolase is not associated with COPD in a community-based sample.
Polymorphism in gene for microsomal epoxide hydrolase and lung disease.
Lung Neoplasms
A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers.
Aromatic DNA adducts and number of lung cancer risk alleles in Map-Ta-Phut Industrial Estate workers and nearby residents.
Association between EPHX1 rs1051740 and lung cancer susceptibility: a meta-analysis.
Association between lung cancer and microsomal epoxide hydrolase genotypes.
Association between microsomal epoxide hydrolase 1 T113C polymorphism and susceptibility to lung cancer.
Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma.
Association of functionally important polymorphism of microsomal epoxide hydrolase gene (EPHX1) with lung cancer susceptibility.
Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk.
Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients.
Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer.
EPHX1 A139G polymorphism and lung cancer risk: a meta-analysis.
EPHX1 gene polymorphisms and individual susceptibility to lung cancer.
EPHX1 polymorphisms and the risk of lung cancer: a HuGE review.
EPHX1 rs2234922 polymorphism and lung cancer susceptibility in Asian populations: a meta-analysis.
Functional polymorphisms of the microsomal epoxide hydrolase gene: A reappraisal on a early-onset lung cancer patients series.
Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk.
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer.
Genetic Polymorphism of Epoxide Hydrolase and GSTM1 in Lung Cancer Susceptibility of Korean Population.
Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients.
Genetic polymorphisms and lung cancer susceptibility: a review.
Genetic polymorphisms in N-acetyltransferase-2 and microsomal epoxide hydrolase, cumulative cigarette smoking, and lung cancer.
Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer.
Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China.
Impact of epoxide hydrolase 1 polymorphisms on lung cancer susceptibility in asian populations.
Lung cancer risk in relation to genetic polymorphisms of microsomal epoxide hydrolase among African-Americans and Caucasians in Los Angeles County.
Lung cancer susceptibility in relation to combined polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1.
Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese.
Microsomal epoxide hydrolase polymorphisms and lung cancer risk in non-Hispanic whites.
Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review.
Multiple analytical approaches reveal distinct gene-environment interactions in smokers and non smokers in lung cancer.
Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.
Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer.
Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer.
Polymorphisms in the microsomal epoxide hydrolase gene: role in lung cancer susceptibility and prognosis.
Quantitative assessment of the effects of the EPHX1 Tyr113His polymorphism on lung and breast cancer.
The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans.
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer.
[The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer]
Lymphoma
Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas.
Lymphoma, B-Cell
Genetic variation in metabolic genes, occupational solvent exposure, and risk of non-hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Metabolic gene variants and risk of non-Hodgkin's lymphoma.
Macular Degeneration
Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration.
Medulloblastoma
Maternal variation in EPHX1, a xenobiotic metabolism gene, is associated with childhood medulloblastoma: an exploratory case-parent triad study.
Mesothelioma
Metabolic genotypes as modulators of asbestos-related pleural malignant mesothelioma risk: a comparison of Finnish and Italian populations.
microsomal epoxide hydrolase deficiency
Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment.
Mouth Neoplasms
Lack of Association of EPHX1 Genotypes and Haplotypes with Oral Cancer in South Indians.
Multifocal epithelial hyperplasia: A potentially precancerous disease? (Review).
Myocardial Infarction
Microsomal epoxide hydrolase genotype and risk of myocardial infarction.
Neoplasm Metastasis
Epithelioid hemangioendothelioma of the mandibular gingiva: A rare case of metastasis 4 years after radical excision and literature review.
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer.
Neoplasms
A phylogenetic analysis identifies heterogeneity among hepatocellular carcinomas.
Association between head and neck cancer and microsomal epoxide hydrolase genotypes.
Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.
Association of microsomal epoxide hydrolase exon 3 Tyr113His and exon 4 His139Arg polymorphisms with gastric cancer in India.
Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.
Comparison of enzyme phenotypes in human bladder tumours and experimentally induced hyperplastic and neoplastic lesions of the rat urinary bladder. A combined histochemical and immunohistochemical approach.
Developmental expression of human microsomal epoxide hydrolase.
Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
Effect of epoxide hydrolase polymorphisms on chromosome aberrations and risk for lung cancer.
Effects of chemical inducers on human microsomal epoxide hydrolase in primary hepatocyte cultures.
EPHX1 gene polymorphisms and individual susceptibility to lung cancer.
Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study.
Epoxide hydrolase genotype and orolaryngeal cancer risk: interaction with GSTM1 genotype.
Expression of xenobiotic metabolizing enzymes in breast cancer.
Functional polymorphisms of the microsomal epoxide hydrolase gene: A reappraisal on a early-onset lung cancer patients series.
Genetic polymorphism and cancer risk.
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer.
Genetic polymorphisms in chronic obstructive pulmonary disease.
Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India.
Genetically lowered microsomal epoxide hydrolase activity and tobacco-related cancer in 47,000 individuals.
Genetics of chronic obstructive pulmonary disease, beyond a1-antitrypsin deficiency.
Glutathione-S-transferase and microsomal epoxide hydrolase polymorphism and viral-related hepatocellular carcinoma risk in India.
Haplotypes of Microsomal Epoxide Hydrolase and X-Ray Cross-Complementing Group 1 Genes in Indian Hepatocellular Carcinoma Patients.
High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.
Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression.
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans.
Localization of microsomal epoxide hydrolase in normal and neoplastic human kidney.
Low microsomal epoxide hydrolase expression is associated with bladder carcinogenesis and recurrence.
Lung cancer susceptibility in relation to combined polymorphisms of microsomal epoxide hydrolase and glutathione S-transferase P1.
Metabolic genotypes as modulators of asbestos-related pleural malignant mesothelioma risk: a comparison of Finnish and Italian populations.
Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer.
Microsomal epoxide hydrolase 1 (EPHX1): Gene, structure, function, and role in human disease.
Microsomal epoxide hydrolase expression as a predictor of tamoxifen response in primary breast cancer: a retrospective exploratory study with long-term follow-up.
Microsomal Epoxide Hydrolase Polymorphisms and Haplotypes as Determinants of Hepatitis B Virusand Hepatitis C Virus-related Liver Disease in Indian Population.
Polymorphic enzymes of xenobiotic metabolism as modulators of acquired P53 mutations in bladder cancer.
Polymorphisms for chemical metabolizing genes and risk for cervical neoplasia.
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers: A Comprehensive Meta-Analysis.
Quantitative assessment of the influence of EPHX1 gene polymorphisms and cancer risk: a meta-analysis with 94,213 subjects.
Reduction of dihydrodiol dehydrogenase expression in resected hepatocellular carcinoma.
Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics.
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS Study.
Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor.
Species differences in enzymes controlling reactive epoxides.
The role of epoxide hydrolase Y113H gene variant in pancreatic diseases.
[Genetics risk factors in chronic obstructive pulmonary disease]
[Relation Between microsomal epoxide hydrolase polymorphism and susceptibility to ovarian epithelial cancer]
Neurotoxicity Syndromes
Interaction between smoking and glutathione S-transferase polymorphisms in solvent-induced chronic toxic encephalopathy.
[The role of smoking and metabolic enzyme polymorphisms in the organic solvent induced chronic encephalopathy].
Obesity
Impact of Obesity on Ovotoxicity Induced by 7,12-dimethylbenz[a]anthracene in Mice.
Progressive obesity alters ovarian insulin, phosphatidylinositol-3 kinase, and chemical metabolism signaling pathways and potentiates ovotoxicity induced by phosphoramide mustard in mice.
Progressive obesity alters ovarian insulin, phosphatidylinositol-3 kinase, and chemical metabolism signaling pathways and potentiates ovotoxicity induced by phosphoramide mustard in mice†.
Optic Atrophy, Hereditary, Leber
Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset.
Optic Nerve Diseases
Genetic variants of TP53 and EPHX1 in Leber's hereditary optic neuropathy and their relationship to age at onset.
Oropharyngeal Neoplasms
High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers.
Ovarian Neoplasms
Association between EPHX1 polymorphism rs1051740 and the risk of ovarian cancer: a meta-analysis.
mEH Tyr113His polymorphism and the risk of ovarian cancer development.
Microsomal epoxide hydrolase polymorphism and susceptibility to ovarian cancer.
Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer.
Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma.
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
The microsomal epoxide hydrolase Tyr113His polymorphism: association with risk of ovarian cancer.
Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk.
Pancreatic Diseases
The role of epoxide hydrolase Y113H gene variant in pancreatic diseases.
Papilloma
Human papillomavirus detection in histologic samples of multifocal epithelial hyperplasia: a novel demographic presentation.
Parkinson Disease
Genetic polymorphisms of microsomal and soluble epoxide hydrolase and the risk of Parkinson's disease.
GSTM1 and mEPHX polymorphisms in Parkinson's disease and age of onset.
Pharyngeal Neoplasms
CYP1A1, mEH, and GSTM1 Polymophisms and Risk of Oral and Pharyngeal Cancer: A Spanish Case-Control Study.
Pneumoconiosis
[Gene variance in microsomal epoxide hydrolase and the susceptibility of coal workers' pneumoconiosis].
Pneumonia
Genetic polymorphisms in the cytochromes P-450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children.
Polycystic Kidney Diseases
Inhibition of catalase and epoxide hydrolase by the renal cystogen 2-amino-4,5-diphenylthiazole and its metabolites.
Polycystic Kidney, Autosomal Recessive
Inhibition of catalase and epoxide hydrolase by the renal cystogen 2-amino-4,5-diphenylthiazole and its metabolites.
Polycystic Ovary Syndrome
Quantitative Methylation Level of the EPHX1 Promoter in Peripheral Blood DNA Is Associated with Polycystic Ovary Syndrome.
Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are associated with polycystic ovary syndrome.
Pre-Eclampsia
A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia.
Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women.
eNOSI4 and EPHX1 polymorphisms affect maternal susceptibility to preeclampsia: analysis of five polymorphisms predisposing to cardiovascular disease in 279 Caucasian and 241 African women.
PP057. ENOSI4 and EPHX1 polymorphisms affect maternal susceptibility topreeclampsia - Analysis of five polymorphisms predisposing tocardiovascular disease in 279 caucasian and 241 african women.
Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between polymorphisms of EPHX1 and XRCC1 genes and the risk of childhood acute lymphoblastic leukemia.
Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children.
Prostatic Neoplasms
Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.
Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: gene-environment interaction and risk of prostate cancer.
Microsomal epoxide hydrolase gene polymorphisms and susceptibility to prostate cancer: A systematic review.
Microsomal epoxide hydrolase polymorphisms, cigarette smoking and prostate cancer risk in the Slovak population.
Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk.
Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer.
Protein-Energy Malnutrition
Prevention of c-Jun/activator protein-1 activation and microsomal epoxide hydrolase induction in the rat liver by cysteine during protein-calorie malnutrition.
Pulmonary Disease, Chronic Obstructive
A bioinformatics strategy for detecting the complexity of Chronic Obstructive Pulmonary Disease in Northern Chinese Han Population.
Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study.
Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema.
Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses.
Association of Functional Variants of Phase I and II Genes with Chronic Obstructive Pulmonary Disease in a Serbian Population.
Combined analysis of EPHX1, GSTP1, GSTM1 and GSTT1 gene polymorphisms in relation to chronic obstructive pulmonary disease risk and lung function impairment.
Correlation of EPHX1, GSTP1, GSTM1, and GSTT1 genetic polymorphisms with antioxidative stress markers in chronic obstructive pulmonary disease.
Decreased expression of antioxidant enzymes and increased expression of chemokines in COPD lung.
Detection of polymorphisms at exons 3 (Tyr113-->His) and 4 (His139-->Arg) of the microsomal epoxide hydrolase gene using fluorescence PCR method combined with melting curves analysis.
Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes.
EPHX1 polymorphisms, COPD and asthma in 47,000 individuals and in meta-analysis.
EPHX1 Y113H polymorphism is associated with increased risk of chronic obstructive pulmonary disease in Kazakhstan population.
Exploration of association between EPHX1 and chronic obstructive pulmonary disease on the basis of combined data mining.
Exploring the interaction among EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population.
Genes, oxidative stress, and the risk of chronic obstructive pulmonary disease.
Genetic association analysis of COPD candidate genes with bronchodilator responsiveness.
Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1.
Genetic associations with hypoxemia and pulmonary arterial pressure in COPD.
Genetic determinants of emphysema distribution in the national emphysema treatment trial.
Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD.
Genetic polymorphisms in chronic obstructive pulmonary disease.
Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD.
Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1.
Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD.
Genetic variations in detoxification enzymes and HIF-1? in Japanese patients with COPD.
Genetics of COPD.
Glutathione S-transferase and microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease in Slovak population.
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.
Lack of association between glutathione S-transferase P1 polymorphism and COPD in Koreans.
Microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease: A comprehensive meta-analysis.
Microsomal Epoxide Hydrolase Gene Polymorphisms and Susceptibility to Chronic Obstructive Pulmonary Disease in Tunisian Population.
Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese.
Microsomal epoxide hydrolase is not associated with COPD in a community-based sample.
Oxidative Stress and Genetic Variants of Xenobiotic-Metabolising Enzymes Associated with COPD Development and Severity in Serbian Adults.
Polymorphic variation in surfactant protein B is associated with COPD exacerbations.
Polymorphism of microsomal epoxide hydrolase is associated with chronic obstructive pulmonary disease and bronchodilator response.
Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD.
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Relationship between COPD and polymorphisms of HOX-1 and mEPH in a Chinese population.
Relationship between polymorphisms of genes encoding microsomal epoxide hydrolase and glutathione S-transferase P1 and chronic obstructive pulmonary disease.
Susceptibility genes for rapid decline of lung function in the lung health study.
Update in chronic obstructive pulmonary disease: role of antioxidant and metabolizing gene polymorphisms.
[Association between polymorphisms in the microsomal epoxide hydrolase (mEH) gene and chronic obstructive pulmonary disease]
[Genetic risk factors for chronic obstructive pulmonary disease (COPD)]
[Genetics risk factors in chronic obstructive pulmonary disease]
[Microsomal epoxide hydrolase gene polymorphism and susceptibility to chronic obstructive pulmonary disease in Han nationality of North China]
[Role of genetic factors in the development of COPD]
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Respiratory Tract Diseases
[Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]
Seizures
Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population.
Sepsis
Urinary excretion of 3-methylhistidine: an assessment of muscle protein catabolism in adult normal subjects and during malnutrition, sepsis, and skeletal trauma.
Skin Diseases
[Role of polymorphous genes of xenobiotic biotransformation system in pathogenesis of occupational allergic dermatoses].
Skin Neoplasms
Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan.
Small Cell Lung Carcinoma
Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients.
[The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer]
Spinal Cord Injuries
Motor enrichment sustains hindlimb movement recovered after spinal cord injury and glial transplantation.
Neuroprotective Effects of Hypothermia Following Spinal Cord Injury in Rats: Comparative Study Between Epidural Hypothermia and Systemic Hypothermia.
Stevens-Johnson Syndrome
Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy.
Stomach Neoplasms
Association of microsomal epoxide hydrolase exon 3 Tyr113His and exon 4 His139Arg polymorphisms with gastric cancer in India.
Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean.
Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.
Urinary Bladder Neoplasms
Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk.
Genetic polymorphisms of cytochrome P450 CYP1A1 (*2A) and microsomal epoxide hydrolase gene, interactions with tobacco-users, and susceptibility to bladder cancer: a study from North India.
Virus Diseases
Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A.
Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of "preneoplastic antigen"-like molecules.