show all | hide all No of entries

Information on EC 3.3.1.1 - adenosylhomocysteinase

for references in articles please use BRENDA:EC3.3.1.1
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.3 Acting on ether bonds
             3.3.1 Thioether and trialkylsulfonium hydrolases
                3.3.1.1 adenosylhomocysteinase
IUBMB Comments
The enzyme contains one tightly bound NAD+ per subunit. This appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond (for mechanism, click here), cf. EC 5.5.1.4, inositol-3-phosphate synthase.
Specify your search results
Select one or more organisms in this record:
Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
adenosylhomocysteine hydrolase, AdoHcy hydrolase, AdoHcyase, AdoHcyHD, AdoHyc hydrolase, AHCY, amphiSAHH, AtSAHH1, AtSAHH2, CUBP, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine
show the reaction diagram