Reference on EC 3.2.2.31 - adenine glycosylase
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Chepanoske, C.L.; Golinelli, M.P.; Williams, S.D.; David, S.S.
Positively charged residues within the iron-sulfur cluster loop of E. coli MutY participate in damage recognition and removal
Arch. Biochem. Biophys.
380
11-19
2000
Escherichia coli (P17802), Escherichia coli
Lu, A.L.; Lee, C.Y.; Li, L.; Li, X.
Physical and functional interactions between Escherichia coli MutY and endonuclease VIII
Biochem. J.
393
381-387
2006
Escherichia coli
Michaels, M.L.; Tchou, J.; Grollman, A.P.; Miller, J.H.
A repair system for 8-oxo-7,8-dihydrodeoxyguanine
Biochemistry
31
10964-10968
1992
Escherichia coli
Porello, S.L.; Leyes, A.E.; David, S.S.
Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates
Biochemistry
37
14756-14764
1998
Escherichia coli
Porello, S.L.; Cannon, M.J.; David, S.S.
A substrate recognition role for the [4Fe-4S]2+ cluster of the DNA repair glycosylase MutY
Biochemistry
37
6465-6475
1998
Escherichia coli
Williams, S.D.; David, S.S.
Formation of a Schiff base intermediate is not required for the adenine glycosylase activity of Escherichia coli MutY
Biochemistry
38
15417-15424
1999
Escherichia coli
Williams, S.D.; David, S.S.
A single engineered point mutation in the adenine glycosylase MutY confers bifunctional glycosylase/AP lyase activity
Biochemistry
39
10098-10109
2000
Escherichia coli (P17802), Escherichia coli
Messick, T.E.; Chmiel, N.H.; Golinelli, M.P.; Langer, M.R.; Joshua-Tor, L.; David, S.S.
Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster
Biochemistry
41
3931-3942
2002
Escherichia coli (P17802), Escherichia coli
Chepanoske, C.L.; Lukianova, O.A.; Lombard, M.; Golinelli-Cohen, M.P.; David, S.S.
A residue in MutY important for catalysis identified by photocross-linking and mass spectrometry
Biochemistry
43
651-662
2004
Escherichia coli
Livingston, A.L.; Kundu, S.; Henderson Pozzi, M.; Anderson, D.W.; David, S.S.
Insight into the roles of tyrosine 82 and glycine 253 in the Escherichia coli adenine glycosylase MutY
Biochemistry
44
14179-14190
2005
Escherichia coli
Eberle, R.J.; Coronado, M.A.; Caruso, I.P.; Lopes, D.O.; Miyoshi, A.; Azevedo, V.; Arni, R.K.
Chemical and thermal influence of the [4Fe-4S]2+ cluster of A/G-specific adenine glycosylase from Corynebacterium pseudotuberculosis
Biochim. Biophys. Acta
1850
393-400
2015
Corynebacterium pseudotuberculosis, Corynebacterium pseudotuberculosis ADK29561.1
Chang, P.; Madabushi, A.; Lu, A.
Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity
BMC Biochem.
10
19
2009
Escherichia coli
Brinkmeyer, M.K.; Pope, M.A.; David, S.S.
Catalytic contributions of key residues in the adenine glycosylase MutY revealed by pH-dependent kinetics and cellular repair assays
Chem. Biol.
19
276-286
2012
Escherichia coli (P17802)
Eutsey, R.; Wang, G.; Maier, R.J.
Role of a MutY DNA glycosylase in combating oxidative DNA damage in Helicobacter pylori
DNA Repair
6
19-26
2007
Helicobacter pylori
de Faria, R.C.; Vila-Nova, L.G.; Bitar, M.; Resende, B.C.; Arantes, L.S.; Rebelato, A.B.; Azevedo, V.A.; Franco, G.R.; Machado, C.R.; Santos, L.L.; de Oliveira Lopes, D.
Adenine glycosylase MutY of Corynebacterium pseudotuberculosis presents the antimutator phenotype and evidences of glycosylase/AP lyase activity in vitro
Infect. Genet. Evol.
44
318-329
2016
Corynebacterium pseudotuberculosis
Manuel, R.C.; Czerwinski, E.W.; Lloyd, R.S.
Identification of the structural and functional domains of MutY, an Escherichia coli DNA mismatch repair enzyme
J. Biol. Chem.
271
16218-16226
1996
Escherichia coli
Wright, P.M.; Yu, J.; Cillo, J.; Lu, A.L.
The active site of the Escherichia coli MutY DNA adenine glycosylase
J. Biol. Chem.
274
29011-29018
1999
Escherichia coli
Pope, M.A.; Porello, S.L.; David, S.S.
Escherichia coli apurinic-apyrimidinic endonucleases enhance the turnover of the adenine glycosylase MutY with G A substrates
J. Biol. Chem.
277
22605-22615
2002
Escherichia coli
Wong, I.; Bernards, A.S.; Miller, J.K.; Wirz, J.A.
A dimeric mechanism for contextual target recognition by MutY glycosylase
J. Biol. Chem.
278
2411-2418
2003
Escherichia coli
Manuel, R.C.; Hitomi, K.; Arvai, A.S.; House, P.G.; Kurtz, A.J.; Dodson, M.L.; McCullough, A.K.; Tainer, J.A.; Lloyd, R.S.
Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase
J. Biol. Chem.
279
46930-46939
2004
Escherichia coli
Volk, D.; Thiviyanathan, V.; House, P.; Lloyd, R.; Gorenstein, D.
Letter to the editor 1H, 13C and 15N resonance assignments of the C-terminal domain of MutY An adenine glycosylase active on G A mismatches
J. Biomol. NMR
14
385-386
1999
Escherichia coli
-
Chmiel, N.H.; Livingston, A.L.; David, S.S.
Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E.coli enzymes
J. Mol. Biol.
327
431-443
2003
Homo sapiens
Chang, D.Y.; Gu, Y.; Lu, A.L.
Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide
Mol. Genet. Genomics
266
336-342
2001
Schizosaccharomyces pombe
Michaels, M.L.; Pham, L.; Nghiem, Y.; Cruz, C.; Miller, J.H.
MutY, an adenine glycosylase active on G-A mispairs, has homology to endonuclease III
Nucleic Acids Res.
18
3841-3845
1990
Escherichia coli
Williams, S.D.; David, S.S.
Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA
Nucleic Acids Res.
26
5123-5133
1998
Escherichia coli
Chepanoske, C.L.; Porello, S.L.; Fujiwara, T.; Sugiyama, H.; David, S.S.
Substrate recognition by Escherichia coli MutY using substrate analogs
Nucleic Acids Res.
27
3197-3204
1999
Escherichia coli
Chmiel, N.H.; Golinelli, M.P.; Francis, A.W.; David, S.S.
Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain
Nucleic Acids Res.
29
553-564
2001
Escherichia coli
Ma, H.; Lee, H.M.; Englander, E.W.
N-terminus of the rat adenine glycosylase MYH affects excision rates and processing of MYH-generated abasic sites
Nucleic Acids Res.
32
4332-4339
2004
Rattus norvegicus (Q8R5G2)
Woods, R.D.; OShea, V.L.; Chu, A.; Cao, S.; Richards, J.L.; Horvath, M.P.; David, S.S.
Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases
Nucleic Acids Res.
44
801-810
2016
Geobacillus stearothermophilus (P83847)
Au, K.G.; Clark, S.; Miller, J.H.; Modrich, P.
Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs
Proc. Natl. Acad. Sci. USA
86
8877-8881
1989
Escherichia coli
Trasvina-Arenas, C.H.; Lopez-Castillo, L.M.; Sanchez-Sandoval, E.; Brieba, L.G.
Dispensability of the [4Fe-4S] cluster in novel homologues of adenine glycosylase MutY
FEBS J.
283
521-540
2016
Entamoeba histolytica, Levilactobacillus brevis
Eberle, R.J.; Coronado, M.A.; Peinado, R.S.; de Moraes, F.R.; Olivier, D.; Dreyer, T.; de Oliveira Lopes, D.; da Luz, B.S.R.; Azevedo, V.; Arni, R.K.
The polyanions heparin and suramin impede binding of free adenine to a DNA glycosylase from C. pseudotuberculosis
Int. J. Biol. Macromol.
125
459-468
2019
Corynebacterium pseudotuberculosis
Wang, L.; Lee, S.J.; Verdine, G.L.
Structural basis for avoidance of promutagenic DNA repair by MutY adenine DNA glycosylase
J. Biol. Chem.
290
17096-17105
2015
Geobacillus stearothermophilus (P83847)
Zutterling, C.; Mursalimov, A.; Talhaoui, I.; Koshenov, Z.; Akishev, Z.; Bissenbaev, A.K.; Mazon, G.; Geacintov, N.E.; Gasparutto, D.; Groisman, R.; Zharkov, D.O.; Matkarimov, B.T.; Saparbaev, M.
Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in Escherichia coli
PeerJ
6
e6029
2018
Escherichia coli
Tyugashev, T.; Kuznetsova, A.; Kuznetsov, N.; Fedorova, O.
Interaction features of adenine DNA glycosylase MutY from E. coli with DNA substrates
Russ. J. Bioorg. Chem.
43
13-22
2017
Escherichia coli (P17802)
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