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Adenocarcinoma
Differential role of Wnt signaling and base excision repair pathways in gastric adenocarcinoma aggressiveness.
Adenocarcinoma of Lung
Evaluation of gene expression levels in the diagnosis of lung adenocarcinoma and malignant pleural mesothelioma.
Anemia
Hematopoietic and gastric uracil-DNA glycosylase activity in megaloblastic anemia and in atrophic gastritis with special reference to pernicious anemia.
Anemia, Megaloblastic
Hematopoietic and gastric uracil-DNA glycosylase activity in megaloblastic anemia and in atrophic gastritis with special reference to pernicious anemia.
Anemia, Pernicious
Hematopoietic and gastric uracil-DNA glycosylase activity in megaloblastic anemia and in atrophic gastritis with special reference to pernicious anemia.
Astrocytoma
Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array.
Blast Crisis
Uracil-DNA glycosylase activity in human acute leukemia.
Blister
Enzymatic repair of premutagenic DNA lesions in human epidermis. Quantitation of O6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase activities.
Bloom Syndrome
Abnormal regulation of uracil-DNA glycosylase induction during cell cycle and cell passage in Bloom's syndrome fibroblasts.
Bloom Syndrome
Increased levels of 5-fluorouracil-induced DNA lesions in Bloom's syndrome.
Bloom Syndrome
Normal uracil-DNA glycosylase activity in Bloom's syndrome cells.
Brain Injuries
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.
Breast Neoplasms
Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts.
Breast Neoplasms
Genetic variations in 3'UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response.
Breast Neoplasms
Single nucleotide polymorphisms in uracil-processing genes, intake of one-carbon nutrients and breast cancer risk.
Breast Neoplasms
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.
Carcinogenesis
Differential role of Wnt signaling and base excision repair pathways in gastric adenocarcinoma aggressiveness.
Carcinogenesis
Repair of premutagenic DNA lesions in human fetal tissues: evidence for low levels of O6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase activity in some tissues.
Carcinoma
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
Carcinoma
Significant Contribution of DNA Repair Human 8-Oxoguanine DNA N-Glycosylase 1 Genotypes to Renal Cell Carcinoma.
Carcinoma, Hepatocellular
Comparison at the molecular level of uracil-DNA glycosylases from different origins.
Carcinoma, Hepatocellular
dUTP pyrophosphatase and uracil-DNA glycosylase in rat liver and hepatomas.
Carcinoma, Ovarian Epithelial
Germline whole exome sequencing and large-scale replication identifies FANCM as a likely high grade serous ovarian cancer susceptibility gene.
Carcinoma, Renal Cell
Significant Contribution of DNA Repair Human 8-Oxoguanine DNA N-Glycosylase 1 Genotypes to Renal Cell Carcinoma.
Carcinoma, Squamous Cell
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
Cataract
Polymorphisms of the WRN gene and DNA damage of peripheral lymphocytes in age-related cataract in a Han Chinese population.
Colonic Neoplasms
Functional interaction of Ugene and EBV infection mediates tumorigenic effects.
Colonic Neoplasms
Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.
Colonic Neoplasms
Mechanisms for the involvement of DNA methylation in colon carcinogenesis.
Colonic Neoplasms
Uracil-initiated base excision DNA repair synthesis fidelity in human colon adenocarcinoma LoVo and Escherichia coli cell extracts.
Colorectal Neoplasms
Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition.
Colorectal Neoplasms
Genetic variations in 3'UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response.
Esophageal Neoplasms
Uracil-DNA glycosylase (UNG) rs246079 G/A polymorphism is associated with decreased risk of esophageal cancer in a Chinese population.
Gastritis, Atrophic
Hematopoietic and gastric uracil-DNA glycosylase activity in megaloblastic anemia and in atrophic gastritis with special reference to pernicious anemia.
Glioblastoma
Fidelity and mutational specificity of uracil-initiated base excision DNA repair synthesis in human glioblastoma cell extracts.
Glioblastoma
Uracil-initiated base excision DNA repair synthesis fidelity in human colon adenocarcinoma LoVo and Escherichia coli cell extracts.
Glioma
DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells.
Graves Disease
The 8-oxoguanine DNA N-glycosylase 1 (hOGG1) Ser326Cys variant affects the susceptibility to Graves' disease.
Hepatitis B
Concerted action of activation-induced cytidine deaminase and uracil-DNA glycosylase reduces covalently closed circular DNA of duck hepatitis B virus.
Hepatitis C
[Utilization of Uracil-DNA glycosylase for combining reverse transcription and anti-contamination with polymerase chain reaction in hepatitis C virus]
Herpes Simplex
A 3' coterminal gene cluster in pseudorabies virus contains herpes simplex virus UL1, UL2, and UL3 gene homologs and a unique UL3.5 open reading frame.
Herpes Simplex
A kinetic analysis of substrate recognition by uracil-DNA glycosylase from herpes simplex virus type 1.
Herpes Simplex
Cloning and expression of the uracil-DNA glycosylase inhibitor (UGI) from bacteriophage PBS-1 and crystallization of a uracil-DNA glycosylase-UGI complex.
Herpes Simplex
Computational rationale for the selective inhibition of the herpes simplex virus type 1 uracil-DNA glycosylase enzyme.
Herpes Simplex
Crystallization and preliminary X-ray analysis of the uracil-DNA glycosylase DNA repair enzyme from herpes simplex virus type 1.
Herpes Simplex
Direct measurement of the substrate preference of uracil-DNA glycosylase.
Herpes Simplex
DNA glycosylases.
Herpes Simplex
Gene UL2 of herpes simplex virus type 1 encodes a uracil-DNA glycosylase.
Herpes Simplex
Herpes simplex virus type 1 (HSV-1) uracil-DNA glycosylase: functional expression in Escherichia coli, biochemical characterization, and selective inhibition by 6-(p-n-octylanilino)uracil.
Herpes Simplex
Herpes simplex virus type 1 uracil-DNA glycosylase: isolation and selective inhibition by novel uracil derivatives.
Herpes Simplex
Identification of the coding sequence for herpes simplex virus uracil-DNA glycosylase.
Herpes Simplex
Induction of uracil-DNA glycosylase and dUTP nucleotidohydrolase activity in herpes simplex virus-infected human cells.
Herpes Simplex
Isolation and characterization of a human cDNA encoding uracil-DNA glycosylase.
Herpes Simplex
Isolation of a herpes simplex virus cDNA encoding the DNA repair enzyme uracil-DNA glycosylase.
Herpes Simplex
Molecular modeling and synthesis of inhibitors of herpes simplex virus type 1 uracil-DNA glycosylase.
Herpes Simplex
Purification and characterization of the herpes simplex virus type 2-encoded uracil-DNA glycosylase.
Herpes Simplex
Selective inhibition of herpes simplex virus type-1 uracil-DNA glycosylase by designed substrate analogs.
Herpes Simplex
The structural basis of specific base-excision repair by uracil-DNA glycosylase.
Herpes Simplex
Uracil in OriS of herpes simplex 1 alters its specific recognition by origin binding protein (OBP): does virus induced uracil-DNA glycosylase play a key role in viral reactivation and replication?
Herpes Simplex
Uracil-DNA glycosylase (UNG) influences the melting temperature (T(m)) of herpes simplex virus (HSV) hybridization probes.
Herpes Simplex
Use of the PBS2 uracil-DNA glycosylase inhibitor to differentiate the uracil-DNA glycosylase activities encoded by herpes simplex virus types 1 and 2.
Hyper-IgM Immunodeficiency Syndrome
Clinical Features and Genetic Analysis of Taiwanese Patients with the Hyper IgM Syndrome Phenotype.
Hyper-IgM Immunodeficiency Syndrome
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination.
Hypersensitivity
Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei.
Infections
Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44).
Infections
Clinical Features and Genetic Analysis of Taiwanese Patients with the Hyper IgM Syndrome Phenotype.
Infections
Early events after infection of Escherichia coli by bacteriophage T5. III. Inhibition of uracil-DNA glycosylase activity.
Infections
Human APOBEC3G Can Restrict Retroviral Infection in Avian Cells and Acts Independently of both UNG and SMUG1.
Infections
Molecular analysis of a large cohort of patients with the hyper immunoglobulin M (IgM) syndrome.
Infections
Uracil DNA Glycosylase 2 negatively regulates HIV-1 LTR transcription.
Laryngeal Neoplasms
The Cys326 allele of the 8-oxoguanine DNA N-glycosylase 1 gene as a risk factor in smoking- and drinking-associated larynx cancer.
Leukemia
The DNA-repair enzyme uracil-DNA glycosylase in the human hematopoietic system.
Leukemia
Uracil DNA-glycosylase. Purification and properties of this enzyme isolated from blast cells of acute myelocytic leukemia patients.
Leukemia
Uracil-DNA glycosylase activity in human acute leukemia.
Leukemia L5178
Excision of uracil from bromodeoxyuridine-substituted and U.V.-irradiated DNA in cultured mouse lymphoma cells.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Uracil-DNA glycosylase activity in human acute leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Uracil-DNA glycosylase in benign and malignant maturing human hematopoietic cells.
Leukemia, Myeloid
Uracil DNA-glycosylase. Purification and properties of this enzyme isolated from blast cells of acute myelocytic leukemia patients.
Leukemia, Myeloid, Acute
Uracil DNA-glycosylase. Purification and properties of this enzyme isolated from blast cells of acute myelocytic leukemia patients.
Leukemia, Myeloid, Acute
Uracil-DNA glycosylase activity in human acute leukemia.
Liver Neoplasms, Experimental
dUTP pyrophosphatase and uracil-DNA glycosylase in rat liver and hepatomas.
Lung Neoplasms
DNA repair activity for oxidative damage and risk of lung cancer.
Lung Neoplasms
Interactive effect of cigarette smoking with human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) polymorphisms on the risk of lung cancer: a case-control study in Taiwan.
Lung Neoplasms
The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk.
Lung Neoplasms
Uracil-DNA Glycosylase Expression Determines Human Lung Cancer Cell Sensitivity to Pemetrexed.
Lymphoma, B-Cell
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas.
Lymphoproliferative Disorders
Uracil-DNA glycosylase activity in chronic lymphoproliferative disorders.
Macular Degeneration
ASSOCIATION BETWEEN POLYMORPHISM OF THE DNA REPAIR SMUG1 AND UNG GENES AND AGE-RELATED MACULAR DEGENERATION.
Macular Degeneration
Association of the DNA repair SMUG1 rs3087404 polymorphism and its interaction with high sensitivity C-reactive protein for age-related macular degeneration in Iranian patients.
Macular Degeneration
Interactions among different genetic loci in age-related macular degeneration.
Mesothelioma
Evaluation of gene expression levels in the diagnosis of lung adenocarcinoma and malignant pleural mesothelioma.
Mesothelioma, Malignant
Evaluation of gene expression levels in the diagnosis of lung adenocarcinoma and malignant pleural mesothelioma.
Monkeypox
Substrate Specificity of Homogeneous Monkeypox Virus Uracil-DNA Glycosylase.
Mouth Neoplasms
The joint effect of smoking and hOGG1 genotype on oral cancer in Taiwan.
Myelodysplastic Syndromes
Hematopoietic and gastric uracil-DNA glycosylase activity in megaloblastic anemia and in atrophic gastritis with special reference to pernicious anemia.
Neoplasms
A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer.
Neoplasms
A simplified assay for O6-methylguanine-DNA methyltransferase activity and its application to human neoplastic and non-neoplastic tissues.
Neoplasms
Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers.
Neoplasms
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
Neoplasms
Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts.
Neoplasms
Erratum: The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
Neoplasms
Excision Repair-Initiated Enzyme-Assisted Bicyclic Cascade Signal Amplification for Ultrasensitive Detection of Uracil-DNA Glycosylase.
Neoplasms
Genetic polymorphisms of the DNA repair gene UNG are associated with the susceptibility of rheumatoid arthritis.
Neoplasms
Genetic variations in 3'UTRs of SMUG1 and NEIL2 genes modulate breast cancer risk, survival and therapy response.
Neoplasms
Genome-wide expression profile of sporadic gastric cancers with microsatellite instability.
Neoplasms
Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
Neoplasms
Increased uracil-DNA glycosylase, AP-DNA binding protein and deoxyribonuclease activities in tumor and SV40-transformed cell lines of human origin.
Neoplasms
Interindividual variation in the activity of O6-methyl guanine-DNA methyltransferase and uracil-DNA glycosylase in human organs.
Neoplasms
Label-free and high-throughput bioluminescence detection of uracil-DNA glycosylase in cancer cells through tricyclic cascade signal amplification.
Neoplasms
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner.
Neoplasms
Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice.
Neoplasms
Next-generation sequencing identifies recurrent copy number variations in invasive breast carcinomas from Ghana.
Neoplasms
Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population.
Neoplasms
Single nucleotide polymorphisms in uracil-processing genes, intake of one-carbon nutrients and breast cancer risk.
Neoplasms
Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.
Neoplasms
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.
Neoplasms
The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer.
Neoplasms
The role of deoxyuridine triphosphate nucleotidohydrolase, uracil-DNA glycosylase, and DNA polymerase alpha in the metabolism of FUdR in human tumor cells.
Neoplasms
The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID.
Neoplasms
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Neoplasms
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
Neuroblastoma
DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells.
Osteosarcoma
E2F-1 and a cyclin-like DNA repair enzyme, uracil-DNA glycosylase, provide evidence for an autoregulatory mechanism for transcription.
Ovarian Neoplasms
A common SNP in the uracil-DNA glycosylase gene UNG decreases ovarian cancer risk in BRCA2 mutation carriers.
Pancreatic Neoplasms
A Transcriptome-Wide Association Study (TWAS) Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer.
Papillomavirus Infections
Association of SMUG1 SNPs in Intron Region and Linkage Disequilibrium with Occurrence of Cervical Carcinoma and HPV Infection in Chinese Population.
Paraproteinemias
Uracil-DNA glycosylase activity in chronic lymphoproliferative disorders.
Photosensitivity Disorders
Roles of uracil-DNA glycosylase and apyrimidinic endonucleases in the molecular 5-bromo-2'-deoxyuridine photosensitization in Escherichia coli K-12.
Photosensitivity Disorders
Uracil-DNA glycosylase causes 5-bromodeoxyuridine photosensitization in Escherichia coli K-12.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Uracil-DNA glycosylase activity in human acute leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Uracil-DNA glycosylase activity in human acute leukemia.
Prostatic Neoplasms
A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer.
Pulmonary Disease, Chronic Obstructive
Cigarette Smoke Induces Nucleic Acid Oxidation in Lung Fibroblasts.
Stomach Neoplasms
Berzosertib (VE-822) inhibits gastric cancer cell proliferation via base excision repair system.
Stomach Neoplasms
Induction of miR-31 causes increased sensitivity to 5-FU and decreased migration and cell invasion in gastric adenocarcinoma.
Stomach Neoplasms
Oxidative Stress Upregulates PDCD4 Expression in Patients with Gastric Cancer via miR-21.
Tuberculosis
Complexes of the uracil-DNA glycosylase inhibitor protein, Ugi, with Mycobacterium smegmatis and Mycobacterium tuberculosis uracil-DNA glycosylases.
Tuberculosis
Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications.
Tuberculosis
Structure of uracil-DNA glycosylase from Mycobacterium tuberculosis: insights into interactions with ligands.
Tuberculosis
Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources.
uracil-dna glycosylase deficiency
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination.
uracil-dna glycosylase deficiency
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
uracil-dna glycosylase deficiency
Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.
uracil-dna glycosylase deficiency
Uracil-DNA glycosylase causes 5-bromodeoxyuridine photosensitization in Escherichia coli K-12.
Vaccinia
A Conserved Tripeptide Sequence at the C Terminus of the Poxvirus DNA Processivity Factor D4 Is Essential for Protein Integrity and Function.
Vaccinia
Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase.
Vaccinia
Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase.
Vaccinia
Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit d4 in complex with the a20 N-terminal domain.
Vaccinia
Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA.
Vaccinia
Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly.
Vaccinia
Mutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viability.
Vaccinia
Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Virus Diseases
Herpes simplex virus type 1 uracil-DNA glycosylase: isolation and selective inhibition by novel uracil derivatives.
Vitiligo
Association of Leukotrichia in Vitiligo and Asp148Glu Polymorphism of Apurinic/Apyrimidinic Endonuclease 1.
Waldenstrom Macroglobulinemia
Uracil-DNA glycosylase activity in chronic lymphoproliferative disorders.
Xeroderma Pigmentosum
Association Between Polymorphisms of DNA Repair Genes and Risk of Schizophrenia.
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3.2.2.27 uracil-DNA glycosylase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
