Reference on EC 3.2.1.62 - glycosylceramidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Day, A.J.; Canada, F.J.; Diaz, J.C.; Kroon, P.A.; Mclauchlan, R.; Faulds, C.B.; Plumb, G.W.; Morgan, M.R.A.; Williamson, G.
Dietary flavonoids and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase
FEBS Lett.
468
166-170
2000
Ovis aries, Ovis aries aries
Manually annotated by BRENDA team
Jacob, R.; Weiner, J.R.; Stadge, S.; Naim, H.Y.
Additional N-glycosylation and its impact on the folding of intestinal lactase-phlorizin hydrolase
J. Biol. Chem.
275
10630-10637
2000
Homo sapiens
Manually annotated by BRENDA team
Wuthrich, M.; Sterchi, E.E.
Human lactase-phloizin hydrolase expressed in Cos-1 cells is proteolytically processed by the lysosomal pathway
FEBS Lett.
405
321-327
1997
Homo sapiens
Manually annotated by BRENDA team
Estrada, G.; Krasinski, S.D.; Montgomery, R.K.; Grand, R.J.; Garcia-Valero, J.; Lopez-Tejero, M.D.
Quantitative analysis of lactase-phlorizin hydrolase expression in the absorptive enterocytes of newborn rat small intestine
J. Cell. Physiol.
167
341-348
1996
Rattus sp.
Manually annotated by BRENDA team
Naim, H.Y.
The pro-region of human intestinale lactase-phlorizin hydrolase is enzymatically inactive towards lactose
Biol. Chem. Hoppe-Seyler
376
255-258
1995
Homo sapiens
Manually annotated by BRENDA team
Naim, H.Y.
Processing and transport of human small intestinal lactase-phlorizin hydrolase (LPH). Role of N-linked oligosaccharide modification
FEBS Lett.
342
302-307
1994
Homo sapiens
Manually annotated by BRENDA team
Naim, H.Y.; Lentze, M.J.
Impact of O-glycosylation on the function of human intestinal lactase-phlorizin hydrolase. Characterization of glycoforms varying in enzyme activity and localization of O-glycoside addition
J. Biol. Chem.
267
25494-25504
1992
Homo sapiens
Manually annotated by BRENDA team
Wacker, H.; Keller, P.; Falchetto, R.; Legler, G.; Semenza, G.
Location of the two catalytic sites in intestinal lactase-phlorizin hydrolase
J. Biol. Chem.
267
18744-18752
1992
Oryctolagus cuniculus
Manually annotated by BRENDA team
Mantei, N.; Villa, M.; Enzler, T.; Wacker, H.; Boll, W.; James, P.; Hunziker, W.; Semenza, G.
Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme
EMBO J.
7
2705-2713
1988
Homo sapiens, Oryctolagus cuniculus
Manually annotated by BRENDA team
Buller, H.A.; Montgomery, R.K.; Sasak, W.V.; Grand, R.J.
Biosynthesis, glycosylation, and intracellular transport of intestinal lactase-phlorizin hydrolase in rat
J. Biol. Chem.
262
17206-17211
1987
Rattus sp.
Manually annotated by BRENDA team
Naim, H.Y.; Sterchi, E.E.; Lentze, M.J.
Biosynthesis and maturation of lactase-phlorizin hydrolase in the human small intestinal epithelial
Biochem. J.
241
427-434
1987
Homo sapiens
Manually annotated by BRENDA team
Danielsen, E.M.; Skovbjerg, H.; Noren, O.; Sjöström, H.
Biosynthesis of intestinal microvillar proteins. Intracellular processing of lactase-phlorizin hydrolase
Biochem. Biophys. Res. Commun.
122
82-90
1984
Sus scrofa
Manually annotated by BRENDA team
Skovbjerg, H.; Danielsen, E.M.; Noren, O.; Sjöström, H.
Evidence for biosynthesis of lactase-phlorizin hydrolase as a single-chain high-molecular weight precursor
Biochim. Biophys. Acta
798
247-251
1984
Homo sapiens
Manually annotated by BRENDA team
Skovbjerg, H.; Sjöström, H.; Noren, O.
Purification and characterization of amphiphilic lactase/phlorizin hydrolase from human small intestine
Eur. J. Biochem.
114
653-661
1981
Homo sapiens
Manually annotated by BRENDA team
Skovbjerg, H.; Noren, O.; Sjöström, H.; Danielsen, E.M.; Enevoldsen, B.S.
Further characterization of intestinal lactase/phlorizin hydrolase
Biochim. Biophys. Acta
707
89-97
1982
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Kobayashi, T.; Suzuki, K.
The glycosylceramidase in the murine intestine. Purification and substrate specificity
J. Biol. Chem.
256
7768-7773
1981
Mus musculus
Manually annotated by BRENDA team
Cousineau, J.; Green, J.R.
Isolation and characterization of the proximal and distal forms of lactase-phlorizin hydrolase from the small intestine of the suckling rat
Biochim. Biophys. Acta
615
147-157
1980
Rattus sp.
Manually annotated by BRENDA team
Ramaswamy, S.; Radhakrishnan, A.N.
Lactase-phlorizin hydrolase complex from monkey small intestine. Purification, properties and evidence for two catalytic sites
Biochim. Biophys. Acta
403
446-455
1975
Macaca radiata
Manually annotated by BRENDA team
Birkenmeier, E.; Alpers, D.H.
Enzymatic properties of rat lactase-phlorizin hydrolase
Biochim. Biophys. Acta
350
100-112
1974
Rattus sp.
Manually annotated by BRENDA team
Leese, H.J.; Semenza, G.
On the identity between the small intestine enzymes phlorizin hydrolase and glycosylceramidase
J. Biol. Chem.
248
8170-8173
1973
Rattus sp.
Manually annotated by BRENDA team
Hamaswamy, S.; Radhakrishnan, A.N.
Lactase-phlorizin hydrolase complex from monkey small intestine: Stimulation of phlorizin hydrolase activity by organic acids
Biochem. Biophys. Res. Commun.
54
197-204
1973
Macaca radiata
Manually annotated by BRENDA team
Kraml, J.; Kolinska, J.; Ellederova, D.; Hirsova, D.
beta-Glucosidase (phlorizin hydrolase) activity of the lactase fraction isolated from the small intestinal mucosa of infant rats, and the relationship between beta-glucosidases and beta-galactosidases
Biochim. Biophys. Acta
258
520-530
1972
Rattus sp.
Manually annotated by BRENDA team
Malathi, P.; Crane, R.K.
Phlorizin hydrolase: A beta-glucosidase of hamster intestinal brush border membrane
Biochim. Biophys. Acta
173
245-256
1969
Cricetinae
Manually annotated by BRENDA team
Day, A.J.; Gee, J.M.; DuPont, M.S.; Johnson, I.T.; Williamson, G.
Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter
Biochem. Pharmacol.
65
1199-1206
2003
Rattus norvegicus
Manually annotated by BRENDA team
Arribas, J.C.; Herrero, A.G.; Martin-Lomas, M.; Canada, F.J.; He, S.; Withers, S.G.
Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase
Eur. J. Biochem.
267
6996-7005
2000
Ovis aries
Manually annotated by BRENDA team
Mackey, A.D.; Henderson, G.N.; Gregory, J.F., 3rd
Enzymatic hydrolysis of pyridoxine-5'-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolase
J. Biol. Chem.
277
26858-26864
2002
Rattus norvegicus
Manually annotated by BRENDA team
Jacob, R.; Peters, K.; Naim, H.Y.
Prosequence of human lactase-phlorizin hydrolase modulates the folding of mature enzyme
J. Biol. Chem.
277
8217-8225
2002
Homo sapiens
Manually annotated by BRENDA team
Burrin, D.G.; Stoll, B.; Fan, M.Z.; Dudley, M.A.; Donovan, S.M.; Reeds, P.J.
Oral IGF-I alters the posttranslational processing but not the activity of lactase-phlorizin hydrolase in formula-fed neonatal pigs
J. Nutr.
131
2235-2241
2001
Sus scrofa
Manually annotated by BRENDA team
Sesink, A.L.; Arts, I.C.; Faassen-Peters, M.; Hollman, P.C.
Intestinal uptake of quercetin-3-glucoside in rats involves hydrolysis by lactase phlorizin hydrolase
J. Nutr.
133
773-776
2003
Rattus norvegicus
Manually annotated by BRENDA team
Wilkinson, A.P.; Gee, J.M.; Dupont, M.S.; Needs, P.W.; Mellon, F.A.; Williamson, G.; Johnson, I.T.
Hydrolysis by lactase phlorizin hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro
Xenobiotica
33
255-264
2003
Rattus norvegicus
Manually annotated by BRENDA team
Mizuma, T.; Fuseda, N.; Hayashi, M.
Kinetic characterization of glycosidase activity from disaccharide conjugate to monosaccharide conjugate in Caco-2 cells
J. Pharm. Pharmacol.
57
661-664
2005
Homo sapiens
Manually annotated by BRENDA team
Bosse, T.; Fialkovich, J.J.; Piaseckyj, C.M.; Beuling, E.; Broekman, H.; Grand, R.J.; Montgomery, R.K.; Krasinski, S.D.
Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development
Am. J. Physiol. Gastrointest. Liver Physiol.
292
G1302-G1314
2007
Mus musculus
Manually annotated by BRENDA team
Beau, I.; Cotte-Laffitte, J.; Geniteau-Legendre, M.; Estes, M.K.; Servin, A.L.
An NSP4-dependant mechanism by which rotavirus impairs lactase enzymatic activity in brush border of human enterocyte-like Caco-2 cells
Cell. Microbiol.
9
2254-2266
2007
Homo sapiens
Manually annotated by BRENDA team
Caines, M.E.; Vaughan, M.D.; Tarling, C.A.; Hancock, S.M.; Warren, R.A.; Withers, S.G.; Strynadka, N.C.
Structural and mechanistic analyses of endo-glycoceramidase II, a membrane-associated family 5 glycosidase in the Apo and GM3 ganglioside-bound forms
J. Biol. Chem.
282
14300-14308
2007
Rhodococcus sp.
Manually annotated by BRENDA team
Hayashi, Y.; Okino, N.; Kakuta, Y.; Shikanai, T.; Tani, M.; Narimatsu, H.; Ito, M.
Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase
J. Biol. Chem.
282
30889-30900
2007
Danio rerio, Homo sapiens, Mus musculus, Rattus norvegicus, Tetraodontidae
Manually annotated by BRENDA team
Behrendt, M.; Keiser, M.; Hoch, M.; Naim, H.Y.
Impaired trafficking and subcellular localization of a mutant lactase associated with congenital lactase deficiency
Gastroenterology
136
2295-2303
2009
Homo sapiens
Manually annotated by BRENDA team
Willing, B.P.; Van Kessel, A.G.
Intestinal microbiota differentially affect brush border enzyme activity and gene expression in the neonatal gnotobiotic pig
J. Anim. Physiol. Anim. Nutr. (Berl.)
93
586-595
2008
Sus scrofa
Manually annotated by BRENDA team
Tanaka, T.; Suzuki, A.; Kuranuki, S.; Mochizuki, K.; Suruga, K.; Takase, S.; Goda, T.
Higher expression of jejunal LPH gene in rats fed the high-carbohydrate/low-fat diet compared with those fed the low-carbohydrate/high-fat diet is associated with in vitro binding of Cdx-2 in nuclear proteins to its promoter regions
Life Sci.
83
122-127
2008
Rattus norvegicus
Manually annotated by BRENDA team
Cramm-Behrens, C.I.; Dienst, M.; Jacob, R.
Apical cargo traverses endosomal compartments on the passage to the cell surface
Traffic
9
2206-2220
2008
Homo sapiens
Manually annotated by BRENDA team
Behrendt, M.; Polaina, J.; Naim, H.Y.
Structural hierarchy of regulatory elements in the folding and transport of an intestinal multidomain protein
J. Biol. Chem.
285
4143-4152
2010
Homo sapiens
Manually annotated by BRENDA team
Koek, W.; van Meurs, J.; van der Eerden, B.; Rivadeneira, F.; Zillikens, M.; Hofman, A.; Obermayer-Pietsch, B.; Lips, P.; Pols, H.; Uitterlinden, A.; van Leeuwen, J.
The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake
J. Bone Miner. Res.
25
1980-1987
2010
Homo sapiens
Manually annotated by BRENDA team
Naz, S.; Siddiqi, R.; Dew, T.P.; Williamson, G.
Epigallocatechin-3-gallate inhibits lactase but is alleviated by salivary proline-rich proteins
J. Agric. Food Chem.
59
2734-2738
2011
Rattus norvegicus
Manually annotated by BRENDA team
Ishibashi, Y.; Ikeda, K.; Sakaguchi, K.; Okino, N.; Taguchi, R.; Ito, M.
Quality control of fungus-specific glucosylceramide in Cryptococcus neoformans by endoglycoceramidase-related protein 1 (EGCrP1)
J. Biol. Chem.
287
368-381
2012
Cryptococcus neoformans, Cryptococcus neoformans (H1AE12), Cryptococcus neoformans H99 (H1AE12)
Manually annotated by BRENDA team
Durand, J.; Biarnes, X.; Watterlot, L.; Bonzom, C.; Borsenberger, V.; Planas, A.; Bozonnet, S.; O'Donohue, M.; Faure, R.
A single point mutation alters the transglycosylation/Hydrolysis partition, significantly enhancing the synthetic capability of an endo-glycoceramidase
ACS Catal.
6
8264-8275
2016
Rhodococcus sp. M-777 (O33853)
-
Manually annotated by BRENDA team
Ben Bdira, F.; Jiang, J.; Kallemeijn, W.; de Haan, A.; Florea, B.I.; Bleijlevens, B.; Boot, R.; Overkleeft, H.S.; Aerts, J.M.; Ubbink, M.
Hydrophobic interactions contribute to conformational stabilization of endoglycoceramidase II by mechanism-based probes
Biochemistry
55
4823-4835
2016
Rhodococcus sp. M777 (O33853)
Manually annotated by BRENDA team
Watanabe, T.; Tani, M.; Ishibashi, Y.; Endo, I.; Okino, N.; Ito, M.
Ergosteryl-beta-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation in Saccharomyces cerevisiae
Glycobiology
25
1079-1089
2015
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Manually annotated by BRENDA team