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Disease on EC 3.2.1.36 - hyaluronoglucuronidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abscess
Case Series and Review on Managing Abscesses Secondary to Hyaluronic Acid Soft Tissue Fillers with Recommended Management Guidelines.
Hyaluronidase production in Streptococcus milleri in relation to infection.
Severe Acute Local Reactions to a Hyaluronic Acid-derived Dermal Filler.
Treatment of experimental brain abscess. 2. Effects of combinations of hyaluronidase with antibiotics and dexamethasone.
[Treatment of chronic abscesses of the lung by local administration of antibiotics and hyaluronidase.]
Acne Vulgaris
Production of hyaluronidase by propionibacteria from different origins.
Acquired Immunodeficiency Syndrome
Enzymatic and hemolytic activities of Candida dubliniensis strains.
Excretory urography in the young subject; hyaluronidase and tomography as aids.
Hyalurondiase: both a tumor promoter and suppressor.
Actinomycosis
[The significance of hyaluronidase in the topical treatment of cervicofacial actinomycosis]
Acute Lung Injury
Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan.
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology.
Adenocarcinoma
Actin-resistant DNAse I Expression From Oncolytic Adenovirus Enadenotucirev Enhances Its Intratumoral Spread and Reduces Tumor Growth.
Association of hyaluronidase and breast adenocarcinoma invasiveness.
Determination of DNA synthesis, estrogen receptors, and carcinoembryonic antigen in isolated cellular subpopulations of human breast cancer.
Diagnostic histochemical and immunohistochemical studies in malignant mesothelioma.
Effect of Matrix-Modulating Enzymes on The Cellular Uptake of Magnetic Nanoparticles and on Magnetic Hyperthermia Treatment of Pancreatic Cancer Models In Vivo.
Heterogeneity in the hormonal responsiveness of clones derived from the 13762NF rat mammary tumor.
Hyaluronidase splice variants are associated with histology and outcome in adenocarcinoma and squamous cell carcinoma of the lung.
Increased hyaluronidase expression in more aggressive prostate adenocarcinoma.
Mucin-positive epithelial mesotheliomas: a histochemical, immunohistochemical, and ultrastructural comparison with mucin-producing pulmonary adenocarcinomas.
Overexpression of transmembrane protein 2 (TMEM2), a novel hyaluronidase, predicts poor prognosis in pancreatic ductal adenocarcinoma.
Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.
Phase IB/II Randomized Study of FOLFIRINOX Plus Pegylated Recombinant Human Hyaluronidase Versus FOLFIRINOX Alone in Patients With Metastatic Pancreatic Adenocarcinoma: SWOG S1313.
Treatment of adenocarcinoma of the liver with mitomycin, hyaluronidase, and ethanol: an experimental study in the rat.
Albuminuria
Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis.
Roles of glomerular endothelial hyaluronan in the development of proteinuria.
Alopecia
Reversible Alopecia with Localized Scalp Necrosis After Accidental Embolization of the Parietal Artery with Hyaluronic Acid.
Alzheimer Disease
Glycosaminoglycans in cortical autopsy samples from Alzheimer brain.
Amblyopia
Sudden amblyopia following hyaluronidase (hyalase) in a case of early pterygium. A case report.
Amnesia
Neuroprotective effects of immobilized granulocyte colony-stimulating factor and hyaluronidase.
Amyloidosis
[The development of experimental amyloidosis after the use of heparin, chondroitin sulfate and hyaluronidase]
Anaphylaxis
Anaphylactic shock caused by the epidurally-administered hyalurinidase.
Cloning and molecular characterization of scorpion Buthus martensi venom hyaluronidases: a novel full-length and diversiform noncoding isoforms.
Flow-assisted diagnosis of anaphylaxis to hyaluronidase.
IgE cross-reactivity of phospholipase A2 and hyaluronidase of Apis dorsata (Giant Asian Honeybee) and Apis mellifera (Western Honeybee) venom: Possible use of A. mellifera venom for diagnosis of patients allergic to A. dorsata venom.
Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions.
Role of hyaluronidase in immediate hypersensitivity reaction.
Use of hyaluronidase in plastic surgery: A review.
[Animal experimental studies on immunogenicity, humoral response and danger of anaphylaxis in parenteral administration of hyaluronidase]
[Attempted induction of anaphylactic shock in sensitized animals with intramuscular horse serum associated with hyaluronidase.]
Anemia, Sickle Cell
Pilot Study of Human Recombinant Hyaluronidase-Enhanced Subcutaneous Hydration and Opioid Administration for Sickle Cell Disease Acute Pain Episodes.
Angioedema
Angioedema after ovine hyaluronidase injection for treating hyaluronic acid overcorrection.
Angioedema related to the use of hyaluronidase in cataract surgery.
Subcutaneous administration of human C1 inhibitor with recombinant human hyaluronidase in patients with hereditary angioedema.
Angioedemas, Hereditary
Health-related quality of life with hereditary angioedema following prophylaxis with subcutaneous C1-inhibitor with recombinant hyaluronidase.
Subcutaneous administration of human C1 inhibitor with recombinant human hyaluronidase in patients with hereditary angioedema.
Arachnoiditis
Hyaluronidase as an adjuvant in the management of tuberculous spinal arachnoiditis.
Hyaluronidase as an adjuvant in the treatment of cranial arachnoiditis (hydrocephalus and optochiasmatic arachnoiditis) complicating tuberculous meningitis.
Intrathecal hyaluronidase therapy in tuberculous spinal arachnoiditis.
Intrathecal hyaluronidase treatment of chronic spinal arachnoiditis of noninfective etiology.
Use of intrathecal hyaluronidase in spinal arachnoiditis complicating tuberculous meningitis.
[Administration of intrathecal hyaluronidase in a patient diagnosed with adhesive arachnoiditis]
Arsenic Poisoning
Effects of silencing epididymal vascular endothelial growth factor (VEGF) expression on hyaluronidase (HYD) activity in arsenic poisoning rats through downregulating VEGF receptor 2 (VEGFR2).
Arteriosclerosis
[Effect of cortisone & hyaluronidase on experimental cholesterol arteriosclerosis in rabbits.]
[Effect of hyaluronidase on the course of experimental arteriosclerosis]
[Experiment on a causal therapy of arteriosclerosis with a combination of hyaluronidase and magnesium. 8. On the arteriosclerosis problem.]
Arthritis
Effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on elastase and hyaluronidase activities and its type II collagen expression.
Hyaluronidase enhances cell fusion and synthesis of viral DNA during infection with caprine arthritis encephalitis virus.
Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis.
Local changes in experimental arthritis and the effect on them of hyaluronidase.
Peptides that mimic glycosaminoglycans: high-affinity ligands for a hyaluronan binding domain.
Screening Mucopolysaccharidosis Type IX in Patients with Juvenile Idiopathic Arthritis.
[Activity of acid hydrolases in rat tissues under experimental arthritis]
[The criteria of differentiated diagnostics of early arthritis on the basis of analysis of serum hyaluronidase and deoxyribonuclease activity].
Arthritis, Experimental
[Activity of acid hydrolases in rat tissues under experimental arthritis]
[Hydrolytic enzymes of rat tissues with adjuvant arthritis]
Arthritis, Juvenile
Screening Mucopolysaccharidosis Type IX in Patients with Juvenile Idiopathic Arthritis.
Arthritis, Psoriatic
[Criteria for the differential diagnosis of spondyloarthropathies, by determining serum hyaluronidase activity]
Arthritis, Reactive
[The criteria of differentiated diagnostics of early arthritis on the basis of analysis of serum hyaluronidase and deoxyribonuclease activity].
Arthritis, Rheumatoid
An experiment to assess the diagnostic potential of a hyaluronidase in rheumatoid arthritis.
Clinical investigation of the value of synthetic hyaluronidase inhibitors in rheumatoid arthritis.
Comparison between serological reactions in hyaluronidase treated joint exudate and whole sera from patients with rheumatoid arthritis.
Examination of synovial fluid and serum hyaluronidase activity as a joint marker in rheumatoid arthritis and osteoarthritis patients (by zymography).
Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time reverse transcriptase polymerase chain reaction.
Gene expression and activity of cartilage-degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts.
Hyaluronidase in human somatic tissues and urine: polymorphism and the activity in diseases.
Inhibiting Hyaluronidase in Rheumatoid Arthritis.
Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis.
Quantitative measurement of serum hyaluronic acid molecular weight in rheumatoid arthritis patients and the role of hyaluronidase.
The effects of anti-rheumatoid drugs on the in vitro activity of human serum hyaluronidase.
[Hyaluronidase spreading test; colored indicator during the treatment of rheumatoid arthritis and lupus erythematosus with corticotropin and cortisone.]
[Hyaluronidase spreading test; hemoglobin in acute rheumatoid arthritis.]
[The criteria of differentiated diagnostics of early arthritis on the basis of analysis of serum hyaluronidase and deoxyribonuclease activity].
Arthus Reaction
[Arthus phenomenon after intraepidermal injection of hyaluronidase.]
arylsulfatase (type i) deficiency
Hyaluronidase and sulfatase deficiency in Hurler's syndrome.
Ascariasis
[Effect of hyaluronidase and infection with Hymenolepis nana on the course of larval ascariasis in laboratory animals]
Ascaridiasis
[Influence of hyaluronidase and the infection with Hymenolepis nana on the level of vitamin C in rats with larval ascaridiasis]
Asthma
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology.
Astrocytoma
The impact of extracellular matrix on the chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy.
Atherosclerosis
Hyaluronidase activity in serum of patients with complicated atherosclerosis.
Plasma hyaluronidase activity as an indicator of atherosclerosis in patients with coronary artery disease.
Tissue permeability--a factor in atherogenesis; studies with cortisone and hyaluronidase.
[Hyaluronidase activity of the blood of rabbits of different ages under normal conditions and in experimental atherosclerosis]
[Studies on the effect of certain hormones on experimental atherosclerosis. I. Effect of growth hormone, hydrocortisone and hyaluronidase on blood lipid level in atheromatosis in rabbits; with a review of the effect of growth hormone on blood protein spectrum.]
[Studies on the effect of certain hormones on experimental atherosclerosis. II. Effect of growth hormone, hydrocortisone and hyaluronidase on certain properties of atheromatous vascular wall in rabbits.]
[The effect of hyaluronidase on the course of experimental atherosclerosis]
Atrioventricular Block
Intravenous hyaluronidase therapy for myocardial infarction in man: double-blind trial to assess infarct size limitation.
Bacteremia
Antipneumococcus hyaluronidase activity in human serum; rise in titer following pneumococcus bacteremia with purulent infection of pleura and synovia.
Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates.
[The effect of hyaluronidase, hyaluronic acid and several other substances on post-radiation experimental bacteremia]
Bacterial Infections
Bacterial infection microenvironment-responsive enzymatically degradable multilayer films for multifunctional antibacterial properties.
Investigation of aminomethyl indole derivatives as hyaluronidase inhibitors.
Physiological activities of a beta-glucan produced by Panebacillus polymyxa.
Blindness
"Effectiveness of retrobulbar hyaluronidase injection in an iatrogenic blindness rabbit model using hyaluronic acid filler injection".
A Rethink on Hyaluronidase Injection, Intraarterial Injection, and Blindness: Is There Another Option for Treatment of Retinal Artery Embolism Caused by Intraarterial Injection of Hyaluronic Acid?
An Efficacy and Safety Study of Intra-arterial Recanalization of Occluded Ophthalmic Arteries in Patients with Monocular Blindness Caused by Injection of Hyaluronic Acid in Facial Tissues.
An In Vitro Model Assessing the Penetration of Hyaluronidase through Optic Nerve Dura for Management of Hyaluronic Acid Facial Filler Embolism.
Assessing Retrobulbar Hyaluronidase as a Treatment for Filler-Induced Blindness in a Cadaver Model.
Blindness After Facial Filler Injections: The Role of Extravascular Hyaluronidase on Intravascular Hyaluronic Acid Embolism in the Rabbit Experimental Model.
Commentary on a Rethink on Hyaluronidase Injection, Intra-arterial Injection and Blindness.
Commentary On: "Examining the Role of Retrobulbar Hyaluronidase in Reversing Filler Induced Blindness: A Systematic Review," by Paap MK, Milman T, Ugradar S, Goldberg R, Silkiss RZ.
Commentary on: Blindness After Facial Filler Injections: The Role of Extravascular Hyaluronidase on Intravascular Hyaluronic Acid Embolism in the Rabbit Experimental Model.
Commentary on: Cosmetic Filler Blindness: Recovery After Repeated Hyaluronidase Injections.
Commentary on: Endovascular Hyaluronidase Application Through Superselective Angiography to Rescue Blindness Caused by Hyaluronic Acid Injection.
Cosmetic Filler Blindness: Recovery After Repeated Hyaluronidase Injections.
Discussion: Assessing Retrobulbar Hyaluronidase as a Treatment for Filler-Induced Blindness in a Cadaver Model and Video Discussion: Treatment for Filler-Induced Blindness.
Discussion: Assessing Retrobulbar Hyaluronidase as a Treatment for Filler-Induced Blindness in a Cadaver Model.
Discussion: Effectiveness of Retrobulbar Hyaluronidase Injection in an Iatrogenic Blindness Rabbit Model Using Hyaluronic Acid Filler Injection.
Effectiveness of Retrobulbar Hyaluronidase Injection in an Iatrogenic Blindness Rabbit Model Using Hyaluronic Acid Filler Injection.
Effectiveness of Retrobulbar Hyaluronidase Injection in an Iatrogenic Blindness Rabbit Model Using Hyaluronic Acid Filler Injection: Correction.
Endovascular Hyaluronidase Application Through Superselective Angiography to Rescue Blindness Caused by Hyaluronic Acid Injection.
Examining the Role of Retrobulbar Hyaluronidase in Reversing Filler-Induced Blindness: A Systematic Review.
Life-threatening complication of retrobulbar block. A hypothesis.
RE: 'Effectiveness of Retrobulbar Hyaluronidase Injection in an Iatrogenic Blindness Rabbit Model Using Hyaluronic Acid Filler Injections'.
Reply re: "Commentary on: 'Examining the Role of Retrobulbar Hyaluronidase in Reversing Filler Induced Blindness: A Systemic Review,' by Paap MK, Milman T, Ugradar S, Goldberg R, Silkiss RZ".
Reply to: Assessing Retrobulbar Hyaluronidase as a Treatment for Filler Induced Blindness in a Cadaver Model.
Reply: Effectiveness of Retrobulbar Hyaluronidase Injection in an Iatrogenic Blindness Rabbit Model Using Hyaluronic Acid Filler Injection.
Reply: Video Discussion: Assessing Retrobulbar Hyaluronidase as a Treatment for Filler-Induced Blindness in a Cadaver Model.
Response to "Discussion: Assessing Retrobulbar Hyaluronidase as a Treatment for Filler Induced Blindness in a Cadaver Model"1 and "Treatment for Filler-Induced Blindness-Video Discussion"2.
Role of Retrobulbar Hyaluronidase in Filler-Associated Blindness: Evaluation of Fundus Perfusion and Electroretinogram Readings in an Animal Model.
Soft-tissue Filler-associated Blindness: A Systematic Review of Case Reports and Case Series.
[What's new in interventional dermatology?]
Blister
Production of bullae in pemphigus with hyaluronidase.
Rounding and steroidogenesis of enzyme- and ACTH-treated Y-l mouse adrenal tumor cells.
Bone Resorption
[Effect of testicular lidase and streptococcal hyaluronidase on bone resorption of the alveolar process in experimental periodontal diseases]
Brain Abscess
Degradation of hyaluronate by Streptococcus intermedius strain UNS 35.
Treatment of experimental brain abscess. 2. Effects of combinations of hyaluronidase with antibiotics and dexamethasone.
Brain Diseases
Neuroprotective effects of immobilized granulocyte colony-stimulating factor and hyaluronidase.
Brain Edema
Glycocalyx degradation leads to blood-brain barrier dysfunction and brain edema after asphyxia cardiac arrest in rats.
Brain Injuries, Traumatic
Hyaluronidase reduced edema after experimental traumatic brain injury.
Brain Neoplasms
Glucocorticoids enhance interleukin-4 production to neo-antigen (hyaluronidase) in children immunocompromised with cytostatic drugs.
Hyaluronidase additional to standard chemotherapy improves outcome for children with malignant brain tumors.
Hyaluronidase is more elevated in human brain metastases than in primary brain tumours.
Breast Neoplasms
A dual-targeted hyaluronic acid-gold nanorod platform with triple-stimuli responsiveness for photodynamic/photothermal therapy of breast cancer.
A versatile nanoplatform for synergistic chemo-photothermal therapy and multimodal imaging against breast cancer.
Association of hyaluronidase and breast adenocarcinoma invasiveness.
Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells.
CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells.
Comparison of hyaluronidase expression, invasiveness and tubule formation promotion in ER (-) and ER (+) breast cancer cell lines in vitro.
Development of a novel metastatic breast cancer score based on hyaluronic acid metabolism.
Dual-degradable and injectable hyaluronic acid hydrogel mimicking extracellular matrix for 3D culture of breast cancer MCF-7 cells.
HER2-Targeted PET Imaging and Therapy of Hyaluronan-Masked HER2-Overexpressing Breast Cancer.
HYAL1 overexpression is correlated with the malignant behavior of human breast cancer.
Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo.
Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer.
Hyaluronidase reduces human breast cancer xenografts in SCID mice.
Increased hyaluronidase levels in breast tumor metastases.
Inhibition of hyaluronan degradation by dextran sulphate facilitates characterisation of hyaluronan synthesis: an in vitro and in vivo study.
Isolation, Characterization and Proliferation of Cancer Cells from Breast Cancer Patients.
Modulating Three-Dimensional Microenvironment with Hyaluronan of Different Molecular Weights Alters Breast Cancer Cell Invasion Behavior.
Monitoring enzymatic degradation of pericellular matrices through SERS stamping.
Mucolytic enzyme systems; relationship of hyaluronidase inhibition by blood serum to incidence of mammary cancer in mice.
Novel variants of CD44 arising from alternative splicing: changes in the CD44 alternative splicing pattern of MCF-7 breast carcinoma cells treated with hyaluronidase.
Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase.
Subcutaneous Trastuzumab: A Review in HER2-Positive Breast Cancer.
The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer.
Theranostic size-reducible and no donor conjugated gold nanocluster fabricated hyaluronic acid nanoparticle with optimal size for combinational treatment of breast cancer and lung metastasis.
Trastuzumab/Hyaluronidase-oysk: A New Option for Patients With HER2-Positive Breast Cancer.
Upregulation of HYAL1 Expression in Breast Cancer Promoted Tumor Cell Proliferation, Migration, Invasion and Angiogenesis.
[Effect of silencing of hyaluronidase gene HYAL1 by RNA interference on proliferation of human breast cancer cells]
[Effects of SiRNA-EGFR on the expression of hyaluronidase gene EGFR in human breast cancer cells]
[Promotion of growth of human breast cancer cells MDA231 by human sperm membrane-bound hyaluronidase: an experimental study]
[The relationship between lymphatic metastasis and serum vascular endothelial growth factor C and cyclooxygenase 2 expression in breast cancer]
Bronchitis
In vitro cultivation of cells from the chorioallantoic membrane of chick embryos.
Brucellosis
[ALLERGIC INDICES FOLLOWING INTRADERMAL ADMINISTRATION OF THERAPEUTIC BRUCELLOSIS VACCINE IN ASSOCIATION WITH HYALURONIDASE. (PRELIMINARY REPORT)]
[Brucellosis in rabbits infected by intradermal injection with Brucella melitensis in suspension with hyaluronidase.]
[EFFECT OF THE ENZYME HYALURONIDASE ON ALLERGIC REACTIONS DURING VACCINOTHERAPY OF BRUCELLOSIS.]
[Hyaluronidase content in patients suffering from brucellosis.]
Bursitis
In-Vivo Efficacy of Recombinant Human Hyaluronidase (rHuPH20) Injection for Accelerated Healing of Murine Retrocalcaneal Bursitis and Tendinopathy.
Therapeutic efficacy of low-dose steroid combined with hyaluronidase in ultrasonography-guided intra-articular injections into the shoulder for adhesive capsulitis.
Candidiasis
Effect of hyaluronidase in experimental candidiasis with special reference to lung lesions.
Carcinogenesis
Hyaluronic Acid--an "Old" Molecule with "New" Functions: Biosynthesis and Depolymerization of Hyaluronic Acid in Bacteria and Vertebrate Tissues Including during Carcinogenesis.
Hyaluronidase activity in serum of patients with monoclonal gammapathy.
The effects of hyalurodinase upon tumor formation in BALB/c mice painted with 7,12-dimethylbenz-(a)anthracene.
Carcinoma
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
Antiadhesive antibodies targeting E-cadherin sensitize multicellular tumor spheroids to chemotherapy in vitro.
Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck.
Detection of bladder carcinoma by combined testing of urine for hyaluronidase and cytokeratin 20 RNAs.
Difference of hyaluronidase produced by human tumor cell lines with hyaluronidase present in human serum as revealed by zymography.
Differentiation of adenocarcinoma of the lung from mesothelioma. Periodic acid-Schiff, monoclonal antibodies B72.3, and Leu M1.
Direct detection of hyaluronidase in urine using cationic gold nanoparticles: a potential diagnostic test for bladder cancer.
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Hyaluronan Synthase and Hyaluronidase Expression in Serous Ovarian Carcinoma is Related to Anatomic Site and Chemotherapy Exposure.
Hyaluronidase and CD44 hyaluronan receptor expression in squamous cell laryngeal carcinoma.
Hyaluronidase and the growth of malignant epithelial tumors.
Hyaluronidase as additive to induction chemotherapy in advanced squamous cell carcinoma of the head and neck.
Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo.
Hyaluronidase expression induces prostate tumor metastasis in an orthotopic mouse model.
Hyaluronidase splice variants are associated with histology and outcome in adenocarcinoma and squamous cell carcinoma of the lung.
Hyaluronidase test in serum of malignancy. II. Influence of hyaluronidase on the level of the filtrate reaction in carcinoma.
Increased hyaluronidase expression in more aggressive prostate adenocarcinoma.
Induction and reversal of cell adhesion-dependent multicellular drug resistance in solid breast tumors.
Intravesical chemotherapy of superficial bladder tumors in a controlled trial with cis-platinum versus cis-platinum plus hyaluronidase.
Magnetic resonance imaging visualization of hyaluronidase in ovarian carcinoma.
Respiratory carcinoma cell lines. MUC genes and glycoconjugates.
Reversal by hyaluronidase of adhesion-dependent multicellular drug resistance in mammary carcinoma cells.
Scanning electron microscopy of 7,12-dimethylbenz(a)-anthracene-induced mammary carcinoma in the female Sprague-Dawley rat.
Sensitivity and specificity of urinary hyaluronic Acid and hyaluronidase in detection of bladder transitional cell carcinoma.
The growth rate of two transplantable murine tumors, 3LL lung carcinoma and B16F10 melanoma, is influenced by Hyal-1, a locus determining hyaluronidase levels and polymorphism.
The role of hyaluronan in mesothelium-induced motility of ovarian carcinoma cells.
Update in Systemic and Targeted Therapies in Gastrointestinal Oncology.
[Cisplatin, vindesine and hyaluronidase combined with simultaneous radiotherapy of advanced head and neck tumors]
[Effect of estrogens and stilbenes on the hyaluronidase enzyme system; study of the etiology of body swelling and edema in endocrine therapy of prostatic carcinoma.]
[Hyaluronic acid and hyaluronidase. 2 new bladder carcinoma markers]
[Hyaluronidase concentration in vaginal secretions of patients with cervix carcinoma]
[Hyaluronidase in cytostatic therapy of ENT tumors]
[Inverse effects of hyaluronidase and antihyaluronidase serum on the development of mammary carcinoma in the mouse.]
[Mitosis activity of Ehrlich ascites carcinoma of the albine meuse after intraperitoneal hyaluronidase administration]
[The effect of hyperthermia on tumors. Experimental animal studies on the influence of healthy environment in tumor therapy with short wave hyperthermia, tested by injection of the area surrounding the carcinoma with hyaluronidase.]
Carcinoma, Hepatocellular
An indirect enzymoimmunological assay for hyaluronidase.
Biosynthesis of albumin via a precursor protein in Morris hepatoma 5123tc.
Lysosomal hyaluronidase activity in normal rat liver and in chemically induced hepatomas.
[Characterization of lysosomal-type hyaluronidase in the culture medium of 2 cell lines derived from human hepatomas]
Carcinoma, Large Cell
Differentiation of adenocarcinoma of the lung from mesothelioma. Periodic acid-Schiff, monoclonal antibodies B72.3, and Leu M1.
Carcinoma, Ovarian Epithelial
Elevated hyaluronan concentration without hyaluronidase activation in malignant epithelial ovarian tumors.
Magnetic resonance imaging visualization of hyaluronidase in ovarian carcinoma.
Carcinoma, Papillary
[Normal-sized ovary carcinoma syndrome: histopathological analysis of 14 cases]
Carcinoma, Squamous Cell
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck.
Effects of hyaluronidase on doxorubicin penetration into squamous carcinoma multicellular tumor spheroids and its cell lethality.
Hyaluronidase as additive to induction chemotherapy in advanced squamous cell carcinoma of the head and neck.
Hyaluronidase splice variants are associated with histology and outcome in adenocarcinoma and squamous cell carcinoma of the lung.
[Cisplatin, vindesine and hyaluronidase combined with simultaneous radiotherapy of advanced head and neck tumors]
[Hyaluronidase in cytostatic therapy of ENT tumors]
Carcinoma, Transitional Cell
Intravesical chemotherapy of superficial bladder tumors in a controlled trial with cis-platinum versus cis-platinum plus hyaluronidase.
Sensitivity and specificity of urinary hyaluronic Acid and hyaluronidase in detection of bladder transitional cell carcinoma.
Cardiovascular Diseases
Effect of hyaluronidase on mortality and morbidity in patients with early peaking of plasma creatine kinase MB and non-transmural ischaemia. Multicentre investigation for the limitation of infarct size (MILIS).
Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis.
Carpal Tunnel Syndrome
Dexamethasone versus Hyaluronidase as an Adjuvant to Local Anesthetics in the Ultrasound-guided Hydrodissection of the Median Nerve for the Treatment of Carpal Tunnel Syndrome Patients.
Cataract
A comparison of infero-nasal and infero-temporal sub-Tenon's block.
A comparison of three sub-Tenon's cannulae.
A dose response study of clonidine with local anesthetic mixture for peribulbar block: a comparison of three doses.
Addition of hyaluronidase to lignocaine with adrenaline for retrobulbar anaesthesia in the surgery of senile cataract.
Allergic reaction to hyaluronidase in cataract surgery.
Allergic reaction to hyaluronidase: a rare cause of orbital inflammation after cataract surgery.
Angioedema related to the use of hyaluronidase in cataract surgery.
Articaine versus lidocaine plus bupivacaine for peribulbar anaesthesia in cataract surgery.
Cataract surgery--anaesthesia without hyaluronidase.
Choice of anesthetic agents for peribulbar anesthesia.
Clinical efficacy and pharmacokinetics of 1% ropivacaine and 0.75% bupivacaine in peribulbar anaesthesia for cataract surgery.
Cluster of diplopia cases after periocular anesthesia without hyaluronidase.
Comparison of 1% ropivacaine and a mixture of 2% lignocaine and 0.5% bupivacaine for peribulbar anaesthesia in cataract surgery.
Comparison of 4% articaine and 0.5% levobupivacaine/2% lidocaine mixture for sub-Tenon's anaesthesia in phacoemulsification cataract surgery: a randomised controlled trial.
Comparison of lignocaine 2% with adrenaline, bupivacaine 0.5% with or without hyaluronidase and a mixture of bupivacaine, lignocaine and hyaluronidase for peribulbar block analgesia.
Comparison of orbital muscle akinesia caused by rocuronium versus hyaluronidase mixed to the local anesthetic in single injection peribulbar block for cataract surgery.
Comparison of pH-adjusted bupivacaine 0.75% and a mixture of bupivacaine 0.75% and lidocaine 2%, both with hyaluronidase, in day-case cataract surgery under regional anesthesia.
Comparison of regional ophthalmic anesthesia produced by pH-adjusted 0.75% and 0.5% bupivacaine and 1% and 1.5% etidocaine, all with hyaluronidase.
Comparison of the efficacy of subtenon with peribulbar local anesthesia without hyaluronidase in patients undergoing cataract surgery.
Delayed allergic reaction to hyaluronidase: a rare sequel to cataract surgery.
Delayed hypersensitivity to hyaluronidase (Hyalasetrade mark) used during cataract surgery.
Does the addition of hyaluronidase improve the quality of peribulbar anesthesia in cataract surgery? - A randomized double blinded study.
Effect of hyaluronidase on ocular motility in sub-Tenon's anesthesia: randomized controlled trial.
Effect of injection pressure on the success rate of peribulbar block.
Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery.
Efficacy and comparison of 0.5% levobupivacaine with 0.75% ropivacaine for peribulbar anaesthesia in cataract surgery.
Efficacy and safety of hyaluronidase 75 IU as an adjuvant to mepivacaine for retrobulbar anesthesia in cataract surgery.
Efficacy of varying concentrations of hyaluronidase in peribulbar anaesthesia.
Factors affecting pseudophakic cystoid mascular edema: five randomized trials.
Hyaluronidase (Vitrase)--ISTA: hyaluronidase--ISTA pharmaceuticals.
Hyaluronidase and sodium hyaluronate in cataract surgery.
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
Hyaluronidase toxicity: a possible cause of post-operative periorbital inflammation.
Life-threatening complication of retrobulbar block. A hypothesis.
Orbicular muscle akinesia in regional ophthalmic anaesthesia with pH-adjusted bupivacaine: effects of hyaluronidase and epinephrine.
Orbicular muscle akinesia: a comparison, using electromyography, of three techniques.
Pulsatile ocular blood flow and intraocular pressure during retrobulbar injection of lignocaine: influence of additives.
Randomized controlled trial to evaluate intraocular pressure following sub-Tenon's local anesthesia for cataract surgery: With and without hyaluronidase added to anesthetic solution.
Retrobulbar anesthesia with and without hyaluronidase in extracapsular cataract surgery. A prospective, randomized, double-blind study.
Retrobulbar blockade of somatic, motor, and visual nerves by local anesthetics.
Role of hyaluronidase in diplopia after peribulbar anesthesia for cataract surgery.
Second cluster of strabismus cases after periocular anesthesia without hyaluronidase.
Sodium bicarbonate--an alternative to hyaluronidase in ocular anaesthesia for cataract surgery.
Sub-Tenon's local anaesthesia: the effect of hyaluronidase.
The effect of hyaluronidase on akinesia during cataract surgery.
Value of hyaluronidase in ocular surgical akinesia.
Venous levels of lignocaine and bupivacaine after peribulbar block.
Vertical diplopia following peribulbar anesthesia: the role of hyaluronidase.
[Efficacy of 1% ropivacaine with and without hyaluronidase for peribulbar block]
[Retrobulbar injections of hyaluronidase as a method increasing safety in cataract surgery.]
[Succinyl-bis-cholinester as muscle relaxant and hyaluronidase in cataract extraction.]
Cellulitis
[Treatment of cellulitis by the use of hyaluronidase.]
Cerebral Infarction
Effect of hyaluronidase on experimental cerebral infarct size and mortality.
Cheilitis
Treatment of cheilitis exfoliativa of the lower lip with hyaluronidase; report of four cases.
[Hyaluronidase therapy of cheilitis exfoliativa of the lower lip; 4 case reports.]
Cholelithiasis
[Experimental and clinical studies on the effect of hyaluronidase on cholelithiasis.]
Cholera
Activation of human synovial cells by cholera enterotoxin: correlation of morphological responses with adenylate cyclase activities, and the reversing effects of hyaluronidase.
[Immunochemical and biochemical characteristics of a preventive preparation against cholera, cholerogen-toxoid]
Chondrosarcoma
Forced expression of KIAA1199, a novel hyaluronidase, inhibits tumorigenicity of low-grade chondrosarcoma.
Malignant myxoid endobronchial tumour: a report of two cases with a unique histological pattern.
Membrane-associated hyaluronate-binding activity of chondrosarcoma chondrocytes.
Choroid Hemorrhage
Hyaluronidase allergy simulating expulsive choroidal hemorrhage.
Colitis, Ulcerative
[Value of beta glucuronidase and hyaluronidase determination in Crohn's disease and ulcerative colitis]
Collagen Diseases
Connective tissue reactions; a critical review. II. Hyaluronic acid, hyaluronidase, and the ground substance of the mesenchyme with particular reference to the collagen diseases.
[Collagen diseases and activities of hyaluronidase.]
[Spreading factors, hyaluronidase and mucopolysaccharides; collagenase and collagen disease.]
Colonic Neoplasms
A study of various strategies to enhance the cytotoxic activity of 5-fluorouracil/leucovorin in human colorectal cancer cell lines.
Early biochemical events in mice exposed to cycas and fed a Nigerian-like diet.
Hyaluronidase Enzyme-responsive Targeted Nanoparticles for Effective Delivery of 5-Fluorouracil in Colon Cancer.
Colorectal Neoplasms
A comparison of flow cytometry and immunohistochemistry in human colorectal cancers.
An upconversion luminescence nanoprobe for the ultrasensitive detection of hyaluronidase.
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Hyaluronidases and their inhibitors in the serum of colorectal carcinoma patients.
Telomerase expression of malignant epithelial cells correlates with Dukes' stage in colorectal cancer.
Common Cold
[Treatment of acute and subacute tubal catarrh with pertubal administration of hydrocortisone and hyaluronidase.]
Communicable Diseases
Mucolytic enzyme systems; inhibition of hyaluronidase by serum in infectious diseases.
Compartment Syndromes
Atypical case of hyaluronidase allergy with orbital compartment syndrome and visual loss.
Decompression of an experimental compartment syndrome in dogs with hyaluronidase.
Contracture
Diplopia and ptosis following injection of local anesthesia without hyaluronidase.
Hyaluronidase reversal of increased coronary vascular resistance in ischemic rat hearts.
[ATTEMPTED USE OF HYALURONIDASE IN THE REHABILITATION OF PATIENTS WITH KNEE CONTRACTURES FOLLOWING ACUTE ANTERIOR POLIOMYELITIS.]
[Experience in the use of hydrocortisone and hyaluronidase in the prevention and treatment of contractures]
[Prevention and treatment of posttraumatic contractures using hydrocortisone and hyaluronidase]
Coronary Artery Disease
Plasma hyaluronidase activity as an indicator of atherosclerosis in patients with coronary artery disease.
Coronary Occlusion
A method for demonstrating the efficacy of interventions designed to limit infarct size following coronary occlusion: beneficial effect of hyaluronidase.
CLS 2210, hyaluronidase and the cardiac lymphatic system.
Effects of hyaluronidase and hydrocortisone on myocardial necrosis after coronary occlusion.
Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion.
Influence of hyaluronidase on infarct size following experimental coronary occlusion of short (90') or long (24 hrs) duration.
Mechanism of action of hyaluronidase in decreasing myocardial ischemia post coronary occlusion in the isolated perfused rabbit heart.
Myocardial infarction treated with two lymphagogues, calcium dobesilate (CLS 2210) and hyaluronidase: a coded, placebo-controlled animal study.
The use of hyaluronidase and hydrocortisone in the reduction of myocardial infarct size following coronary occlusion. Experimental and clinical observations.
COVID-19
"COVID-19/SARS-CoV-2 virus spike protein-related delayed inflammatory reaction to hyaluronic acid dermal fillers: a challenging clinical conundrum in diagnosis and treatment".
Craniosynostoses
Tumescent steroid infiltration to reduce postoperative swelling after craniofacial surgery.
Crohn Disease
[Value of beta glucuronidase and hyaluronidase determination in Crohn's disease and ulcerative colitis]
Cryptorchidism
Hyaluronidase levels of rat testes as related to age, hypophysectomy and cryptorchidism.
The effect of hypophysectomy, cryptorchidism, estrogen and androgen upon the level of hyaluronidase in the rat testis.
Cystitis
Intravesical hyaluronidase causes chronic cystitis in a rat model: A potential model of bladder pain syndrome/interstitial cystitis.
Cystitis, Interstitial
Intravesical hyaluronidase causes chronic cystitis in a rat model: A potential model of bladder pain syndrome/interstitial cystitis.
Transurethral intramural injection of hydrocortone hyaluronidase for interstitial cystitis (Hunner's ulcers).
Cysts
A biochemical study on the nature of jaw cysts (III). Instrumental analysis of the viscous component of fluids in ciliated cysts of the maxilla.
Elevated hyaluronan concentration without hyaluronidase activation in malignant epithelial ovarian tumors.
Percutaneous Rupture of a Symptomatic Facet Joint Synovial Cyst Using 2-Needle Distention.
Treatment of jaw cysts with an irrigational method. (II). The effect on the nature of cyst walls and surrounding bone.
Wrist and hand ganglion treatment with hyaluronidase injection and fine needle aspiration: a tropical African perspective.
Decompression Sickness
[Pathogenesis and prophylaxis of decompression sickness in altitude fliers. I. Influence of hyaluronidase on duration of oxygen prebreathing.]
Dehydration
A randomized clinical trial of recombinant human hyaluronidase-facilitated subcutaneous versus intravenous rehydration in mild to moderately dehydrated children in the emergency department.
A systematic review of the evidence for hypodermoclysis to treat dehydration in older people.
Hyaluronan synthases and hyaluronidases in the kidney during changes in hydration status.
Hyaluronidase as an aid to administration of fluid in the treatment of dehydration in infants.
Hyaluronidase-Assisted Resuscitation in Kenya for Severely Dehydrated Children.
Morphology of hyaluronidase-sensitive cell coats as seen in the SEM after freeze-drying.
Subcutaneous infusion of fluid in children.
Treatment of dehydration in infancy using continuous interstitials and hyaluronidase.
Understanding clinical dehydration and its treatment.
Water structuring centers of mammalian cell surfaces.
[Activity of tissue hyaluronidase in albino rat kidney during dehydration and action of exogenous antidiuretic hormone]
[Hyaluronidase activity of Wistar rat blood plasma: effect of dehydration and vasopressin].
[Hyaluronidase in the dehydration of the infant and older child.]
[Practical value of hyaluronidase in the treatment of dehydration in infants in neurotoxic states.]
Dental Caries
A halotolerant hyaluronidase from newly isolated Brevibacterium halotolerans DC1: Purification and characterization.
Caries susceptibility tests, hyaluronidase activity of saliva and dental caries experience.
The hyaluronidase activity of saliva. II. The relationship of hyaluronidase activity to dental caries experience, gingivitis, and oral hygiene in young male adults.
Dental Plaque
Bacterial chondroitinase ABC and hyaluronidase in human dental plaque and inflamed gingiva.
Determination of hyaluronidase activity in dental plaque material.
Hyaluronidase activity of dental plaque material from children with healthy and diseased gingiva.
Hyaluronidase activity of dental plaque material from diabetic and non-diabetic subjects.
Penetration of dental plaque components into gingiva: sequential topical treatments with hyaluronidase and streptococcal polysaccharide in rats.
Dermatitis
Anti-hyaluronidase Activity in Vitro and Amelioration of Mouse Experimental Dermatitis by Tomato Saponin, Esculeoside A.
INVESTIGATIONS INTO THE ETIOLOGY OF DERMATITIS HERPETIFORMIS. II. THE EFFECTS OF SERUM FROM DERMATITIS HERPETIFORMIS CASES AND OF CERTAIN DRUGS ON THE VISCOSITY REDUCTION PROPERTY OF HYALURONIDASE.
Dermatitis Herpetiformis
INVESTIGATIONS INTO THE ETIOLOGY OF DERMATITIS HERPETIFORMIS. II. THE EFFECTS OF SERUM FROM DERMATITIS HERPETIFORMIS CASES AND OF CERTAIN DRUGS ON THE VISCOSITY REDUCTION PROPERTY OF HYALURONIDASE.
[Correlation between hyaluronidase and hyaluronic acid in pemphigus and Duhring's disease.]
Dermatitis, Contact
Failure of hyaluronidase to intensivate or spread contact eczema.
Phytochemical and biological studies of bryophytes.
Dermatofibrosarcoma
Adjuvant therapy with hyaluronidase prior to excision of dermatofibrosarcoma protuberans.
Pretreatment with intralesional hyaluronidase prior to excision of dermatofibrosarcoma protuberans.
Diabetes Insipidus
[Effect of antidiuretic hormone and chlorothiazide on the excretion of hyaluronidase in the urine in diabetes insipidus.]
Diabetes Mellitus
Enhanced activity of serum and urinary hyaluronidases in streptozotocin-induced diabetic Wistar and GK rats.
Improved postprandial glycemic control in patients with type 2 diabetes from subcutaneous injection of insulin lispro with hyaluronidase.
The relationship between aortic stiffness and serum hyaluronidase levels in patients with diabetes mellitus and hypertension.
Diabetes Mellitus, Experimental
Effect of alloxan diabetes on hyaluronidase level of the rat testis.
Diabetes Mellitus, Type 1
A close relationship between type 1 diabetes and vitamin A-deficiency and matrix metalloproteinase and hyaluronidase activities in skin tissues.
Accelerated insulin pharmacokinetics and improved postprandial glycemic control in patients with type 1 diabetes after coadministration of prandial insulins with hyaluronidase.
Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes.
Improved postprandial glycemic control in patients with type 2 diabetes from subcutaneous injection of insulin lispro with hyaluronidase.
Induction of resistance to diabetes in non-obese diabetic mice by targeting CD44 with a specific monoclonal antibody.
Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis.
Subcutaneous injection of hyaluronidase with recombinant human insulin compared with insulin lispro in type 1 diabetes.
Diabetes Mellitus, Type 2
Differences in the mechanism of type 1 and type 2 diabetes-induced skin dryness by using model mice.
Enhanced activity of serum and urinary hyaluronidases in streptozotocin-induced diabetic Wistar and GK rats.
Improved postprandial glycemic control in patients with type 2 diabetes from subcutaneous injection of insulin lispro with hyaluronidase.
Diabetic Nephropathies
Enhanced activity of serum and urinary hyaluronidases in streptozotocin-induced diabetic Wistar and GK rats.
Increased hyaluronidase activity in the kidney of streptozotocin-induced diabetic rats.
Diabetic Retinopathy
Hyaluronidase (Vitrase)--ISTA: hyaluronidase--ISTA pharmaceuticals.
Diphtheria
[Association of hyaluronidase with serum in the treatment of diphtheria.]
[The effect of neuraminidase of C. diphtheriae on the functional capacity of the peritoneal exudate cells of guinea pigs to diphtheria bacilli]
Diplopia
Cluster of diplopia cases after periocular anesthesia without hyaluronidase.
Diplopia after Hyaluronic Acid Gel Injection for Correction of Facial Tear Trough Deformity.
Diplopia and ptosis following injection of local anesthesia without hyaluronidase.
Diplopia cases after periocular anesthesia without hyaluronidase.
Hyaluronidase and diplopia.
Hyaluronidase omission and diplopia.
Persistent vertical binocular diplopia after cataract surgery.
Role of hyaluronidase in diplopia after peribulbar anesthesia for cataract surgery.
Vertical diplopia following peribulbar anesthesia: the role of hyaluronidase.
[Pilot study of the Heidelberg diplopia questionnaire]
Down Syndrome
Increased adhesiveness of Down syndrome fetal fibroblasts in vitro.
Drug Hypersensitivity
Anaphylactic shock caused by the epidurally-administered hyalurinidase.
Dupuytren Contracture
[Combined treatment of Dupuytren's contracture with use of hyaluronidase preparations.]
[Dupuytren's disease. Treatment by local injections with hyaluronidase using a Dermojet]
[Hyaluronidase therapy of Dupuytren's contracture.]
Dysentery
[Activity of the plasmin enzymatic system and of serum hyaluronidase in dysentery]
[Correlations of the level of plasmin system and blood serum hyaluronidase activity with pathology of the large intestine in dysentery]
[Serum hyaluronidase activity of patients with acute dysentery]
Dyslexia
[A critical view of alternative methods for treating visual complaints]
Eclampsia
[The influence of novocaine, phenergan, largactil and hyaluronidase on eclampsism and eclampsia.]
Eczema
[Eczema and hyaluronidase.]
[Failure of hyaluronidase in experimental eczema.]
[Role of hyaluronidase in eczema; trial of anti-hyaluronidase therapy.]
[The local microbial origin of hyaluronidase in eczema.]
[The significance of hyaluronidase for the eczema.]
Edema, Cardiac
[HYALURONIDASE ACTIVITY IN THE BLOOD AND URINE IN CARDIAC EDEMA.]
[Hyaluronidase drainage with kinetin (Schering), a new method for control of cardiac edema.]
Elephantiasis
[Elephantiasis and hyaluronidase; case reports on therapeutic results.]
[Hyaluronidase therapy of elephantiasis.]
[Streptococcal elephantiasis of the lips treated with hyaluronidase.]
[Therapy of elephantiasis with hyaluronidase.]
Elephantiasis, Filarial
The treatment of Bancroftian elephantiasis and observations on hyaluronidase.
Embolism
A Rethink on Hyaluronidase Injection, Intraarterial Injection, and Blindness: Is There Another Option for Treatment of Retinal Artery Embolism Caused by Intraarterial Injection of Hyaluronic Acid?
An In Vitro Model Assessing the Penetration of Hyaluronidase through Optic Nerve Dura for Management of Hyaluronic Acid Facial Filler Embolism.
Arterial Occlusion After Hyaluronic Acid Injection: Treatment With Hyaluronidase and Streptokinase.
Blindness After Facial Filler Injections: The Role of Extravascular Hyaluronidase on Intravascular Hyaluronic Acid Embolism in the Rabbit Experimental Model.
Commentary on: Blindness After Facial Filler Injections: The Role of Extravascular Hyaluronidase on Intravascular Hyaluronic Acid Embolism in the Rabbit Experimental Model.
Comparison of Intra-arterial and Subcutaneous Testicular Hyaluronidase Injection Treatments and the Vascular Complications of Hyaluronic Acid Filler.
Endovascular Hyaluronidase Application Through Superselective Angiography to Rescue Blindness Caused by Hyaluronic Acid Injection.
Experimentally Induced Arterial Embolism by Hyaluronic Acid Injection: Clinicopathologic Observations and Treatment.
Experimentally Induced Arterial Embolism by Hyaluronic Acid Injection: Clinicopathological Observations and Treatment.
Intravenous Hyaluronidase with Urokinase as Treatment for Arterial Hyaluronic Acid Embolism.
Intravenous Hyaluronidase with Urokinase as Treatment for Rabbit Retinal Artery Hyaluronic Acid Embolism.
Is hyaluronidase able to reverse embolism associated with hyaluronic acid filler? An anatomical case study.
Local Cooling as a Step of Treatment for Tissue Ischemia Caused by Hyaluronic Acid Injection-induced Embolism-A Report of 9 Cases.
Management of secondary embolization that arose after intraarterial thrombolytic treatment of cosmetic facial filler-induced arterial occlusion.
Periocular hyaluronic acid fillers: applications, implications, complications.
Reply: Intravenous Hyaluronidase with Urokinase as Treatment for Arterial Hyaluronic Acid Embolism.
Retro or PeriBulbar Injection Techniques to Reverse Visual Loss After Filler Injections.
Successful management of an unusual presentation of impending necrosis following a hyaluronic acid injection embolus and a proposed algorithm for management with hyaluronidase.
Superselective Arterial Hyaluronidase Thrombolysis Is Not an Effective Treatment for Hyaluronic Acid-Induced Retinal Artery Occlusion: Study in a Rabbit Model.
The Role of Hyaluronidase for the Skin Necrosis Caused by Hyaluronic Acid Injection-Induced Embolism: A Rabbit Auricular Model Study.
[What's new in interventional dermatology?]
Empyema, Pleural
[Biochemical decortication by means of hyaluronidase as a new treatment in chronical pleural empyema.]
[Biochemical decortication with hyaluronidase as a new method of treatment of chronic pleural empyemas.]
[Hyaluronidase therapy of pleural empyema with open spontaneous pneumothorax.]
[Role of hyaluronidase in the therapy of thoracic empyemas.]
[The use of hyaluronidase in the treatment of metapneumonic pleural empyema.]
Empyema, Tuberculous
[Permanent cure in a case of fresh tuberculous empyema treated with antibacterial drugs and hyaluronidase.]
Encephalitis
Hyaluronidase enhances cell fusion and synthesis of viral DNA during infection with caprine arthritis encephalitis virus.
The action of hyaluronidase enzyme on St. Louis and western equine encephalitis viruses in the chick embryo.
Encephalomyelitis, Equine
The action of hyaluronidase enzyme on St. Louis and western equine encephalitis viruses in the chick embryo.
Encephalomyelitis, Western Equine
The action of hyaluronidase enzyme on St. Louis and western equine encephalitis viruses in the chick embryo.
Endocarditis
Characterization of Enterococcus faecium isolates and first report of vanB phenotype-vanA genotype incongruence in the Middle East.
Safety of Lactobacillus plantarum ST8Sh and Its Bacteriocin.
Virulence and antimicrobial resistance in clinical Enterococcus faecium.
Endocarditis, Bacterial
Subacute bacterial endocarditis; the use of hyaluronidase as a supplement to penicillin treatment in bacterial endocarditis.
Endocarditis, Subacute Bacterial
Subacute bacterial endocarditis; the use of hyaluronidase as a supplement to penicillin treatment in bacterial endocarditis.
[Penicillin-resistant subacute bacterial endocarditis; rapid recovery after addition of hyaluronidase.]
Endometrial Neoplasms
Hyaluronidase activity in gynaecological cancer tissues with different metastatic forms.
Endometriosis
Pathogenesis of endometriosis--current research.
Erythema
Allergic reaction to hyaluronidase use after hyaluronic acid filler injection.
Effects of the aminophenol analogue p-Dodecylaminophenol on mouse skin.
Hyaluronidase for the management of dextrose extravasation.
Management of amiodarone extravasation with intradermal hyaluronidase.
[Anti-inflammatory action of acemetacin (author's transl)]
[The effect of hyaluronidase on the spreading of tuberculin erythema.]
Exanthema
A randomized controlled trial of local injections of hyaluronidase versus placebo in cancer patients receiving subcutaneous hydration.
Exophthalmos
Cytoenzymology and 3H-thymidine uptake of retro-ocular connective tissue cultures in experimental endocrino-exophthalmos.
Hyaluronidase and experimental exophthalmos.
Hyaluronidase in thyrotropic exophthalmos; report of a case.
Hyaluronidase induced orbital pseudotumor as complication of retrobulbar anesthesia.
The effect of hyaluronidase on experimental exophthalmos.
[Decreasing effect of hyaluronidase on exophthalmos; preliminary publication.]
Eye Diseases
Periorbital myxedema treated with intralesional hyaluronidase.
[The role of hyaluronic acid and hyaluronidase in eye disease.]
Eye Infections
Bacterial enzyme in viral infections: a new concept. The possible role of hyaluronidase in herpes simplex virus keratitis.
Fallopian Tube Diseases
[A NEW CONSERVATIVE METHOD FOR THE TREATMENT OF TUBAL OBSTRUCTION IN STERILE WOMEN. I. ENZYMATIC THERAPY--HYDRO-INTUBATION WITH HYALURONIDASE. (PRELIMINARY COMMUNICATION)]
Fetal Death
Bacterial Hyaluronidase Promotes Ascending GBS Infection and Preterm Birth.
Maternal serum hyaluronidase activity in pregnancy.
Fibroma
Effects of an antihyaluronidase substance and of hyaluronidase on growth of virus-induced fibromas.
Fibrosarcoma
bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells.
CD44 can mediate the adhesion of platelets to hyaluronan.
Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma.
Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death.
Hyaluronidase and collagenase increase the transfection efficiency of gene electrotransfer in different murine tumors.
Hyaluronidase expression in human skin fibroblasts.
Hyaluronidase induces murine L929 fibrosarcoma cells resistant to tumor necrosis factor and Fas cytotoxicity in the presence of actinomycin D.
Focal Infection
[Study of the serum hyaluronidase inhibitor (HI) and hyaluronidase (HD) extracted from palatine tonsills in the tonsillar focal infection]
Ganglion Cysts
Comparative Study of Recurrence and Complications Using Various Sclerosants by Single Dart Technique in Treatment of Ganglion Cysts.
Wrist and hand ganglion treatment with hyaluronidase injection and fine needle aspiration: a tropical African perspective.
Gas Gangrene
Molecular genetic analysis of the nagH gene encoding a hyaluronidase of Clostridium perfringens.
Gingivitis
Hyaluronic acid and hyaluronidase activity in gingival exudate from sites of acute ulcerative gingivitis in man.
The hyaluronidase activity of saliva. II. The relationship of hyaluronidase activity to dental caries experience, gingivitis, and oral hygiene in young male adults.
Glaucoma
Corticosteroid glaucoma.
Effect of hyaluronidase on aqueous outflow resistance in normotensive and glaucomatous eyes of dogs.
Hyaluronidase injections into the vitreous in a case of glaucoma with abolished anterior chamber.
Ultrastructural and morphometric study of corticosteroid glaucoma in rabbits.
Glaucoma, Open-Angle
Effect of subconjunctival injection of hyaluronidase on outflow resistance in normal and in open-angle glaucomatous patients.
[An ultrahistochemical study of the trabecular meshwork in normal and open-angle glaucomatous eyes]
Glioblastoma
Boron neutron capture therapy for glioblastoma: improvement of boron biodistribution by hyaluronidase.
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Expression of variant CD44 epitopes in human astrocytic brain tumors.
Hyaluronidase is more elevated in human brain metastases than in primary brain tumours.
Na2B12H11SH (BSH) in combination with systemic hyaluronidase: a promising concept for boron neutron capture therapy for glioblastoma.
Permeability of Hypogymnia physodes Extract Component-Physodic Acid through the Blood-Brain Barrier as an Important Argument for Its Anticancer and Neuroprotective Activity within the Central Nervous System.
[Hyaluronidase as an adjuvant to cystostatic chemotherapy in glioblastoma]
Glioma
CD44 expression and hyaluronic acid binding of malignant glioma cells.
Hyaluronic acid facilitates glioma cell invasion in vitro.
Hyaluronidase is more elevated in human brain metastases than in primary brain tumours.
Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth.
Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity.
The effect of hyaluronic Acid on the invasiveness of malignant glioma cells : comparison of invasion potential at hyaluronic Acid hydrogel and matrigel.
Glomerulonephritis
Antibody response to bacteriophage hyaluronidase in acute glomerulonephritis after group A streptococcal infection.
Extracellular factors, blood group antigens, and bacteriophage of nephritogenic and nonnephritogenic strains of M-type 12 streptococci.
Mucolytic enzyme systems. XI. Hyaluronidase inhibitor and serum mucoproteins in patients with lipoid nephrosis and acute glomerulonephritis.
Glycogen Storage Disease
[Glycogenosis type II (Pompe's disease) associated with alpha-amylase and hyaluronidase deficiency]
Glycogen Storage Disease Type II
Hyaluronidase increases the biodistribution of acid alpha-1,4 glucosidase in the muscle of Pompe disease mice: an approach to enhance the efficacy of enzyme replacement therapy.
[Glycogenosis type II (Pompe's disease) associated with alpha-amylase and hyaluronidase deficiency]
Gout
[Hyaluronidase and probenecid combination in the treatment of gout.]
Granuloma
Concentrated growth factors gel activated with ozone for facial aesthetics purpose after granuloma removal: a case report.
Isolation and partial characterization of hyaluronidase and exo-polysaccharidases in rat carrageenin granuloma.
[Effect of hyaluronidase on experimental granuloma caused by quartz.]
[Effect of hyaluronidase on foreign body granuloma.]
[GRANULOMAS, HYALURONIDASE ACTIVITY IN THE PERIODONTIUM AND DENTAL TISSUE.]
Graves Disease
Injected Hyaluronidase Reduces the Volume of Exogenous Hyaluronate Fillers in Mice and Results in Clinical Improvement in a Patient with Pretibial Myxedema.
Successful Treatment of Scalp Myxedema with Injected Hyaluronidase: A Case Report.
Head and Neck Neoplasms
Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck.
Hearing Loss, Sudden
[Clinical and experimental use of ATP in internal ear diseases]
Heart Arrest
Cardiopulmonary arrest after retrobular block.
Cardiopulmonary arrest after retrobulbar anesthesia in a patient with an orbital roof defect.
Heart Defects, Congenital
A positive perspective of knowledge, attitude, and practices for health-promoting behaviors of adolescents with congenital heart disease.
Heart Diseases
Effect of hyaluronidase on mortality and morbidity in patients with early peaking of plasma creatine kinase MB and non-transmural ischaemia. Multicentre investigation for the limitation of infarct size (MILIS).
Hemangiosarcoma
Urinary glycosaminoglycan patterns in angiosarcoma of the liver.
Hemarthrosis
The treatment of acute hemophilic hemarthrosis; a report on the use of hyaluronidase.
The use of hyaluronidase in the treatment of acute hemophilic hemarthrosis.
Hematocele
[Hyaluronidase by venous route in the treatment of intrapelvic hematocele. (Experimental observations)]
Hematuria
A side by side comparison of cytology and biomarkers for bladder cancer detection.
Hemiplegia
[Hemiplegia secondary to cerebromeningeal hemorrhage treated with hyaluronidase with complete recovery.]
Hemorrhagic Septicemia
Hyaluronidase and chondroitinase activity of Pasteurella multocida serotype B:2 involved in hemorrhagic septicaemia.
Hyaluronidase production by type B Pasteurella multocida from cases of hemorrhagic septicemia.
Hemorrhoids
HYALURONIDASE IN LOCAL ANESTHESIA FOR SEVERE HEMORRHOIDS AND PROCIDENTIA.
[THE ASSOCIATION OF A HEPARINOID WITH HYALURONIDASE IN THE TOPICAL TREATMENT OF HEMORRHOIDS.]
Hepatitis
Hepatoprotective effects of immobilized granulocyte colony-stimulating factor and hyaluronidase preparation and their mechanisms.
Mechanisms for hepatoprotective effects of hyaluronidase immobilized by the nanotechnology method of electron-beam synthesis.
Hepatitis B
[Efficacy Observation of Yiguanjian Decoction Combined Adefovir Dipivoxil Tablet in Treating HBeAg Negative Chronic Viral Hepatitis B Active Compensated Liver Cirrhosis Patients].
Hepatitis C
Evaluation of serum hyaluronic acid level and hyaluronidase activity in acute and chronic hepatitis C.
Hepatitis C, Chronic
Evaluation of serum hyaluronic acid level and hyaluronidase activity in acute and chronic hepatitis C.
Hepatitis, Chronic
[Intracellular distribution of hyaluronidase in rats with acute and chronic hepatitis and reparative liver regeneration]
Hereditary Sensory and Motor Neuropathy
Biodegradable hybrid mesoporous silica nanoparticles for gene/chemo-synergetic therapy of breast cancer.
Herpes Simplex
Bacterial enzyme in viral infections: a new concept. The possible role of hyaluronidase in herpes simplex virus keratitis.
Herpes Zoster
Aging, hyaluronidase removal of the cumulus, and microinjection do not affect the sperm binding potential of human oocytes.
Equine sperm-oocyte interaction: the role of sperm surface hyaluronidase.
Hyaluronidase dissolves a component in the hamster zona pellucida.
Improved fertilization and implantation rates after non-touch zona pellucida microdrilling of mouse oocytes with a 1.48 microm diode laser beam.
In vitro fertilization rate of horse oocytes with partially removed zonae.
In vitro penetration of hamster oocyte-cumulus complexes using physiological numbers of sperm.
Inhibition of fertilization in the hamster by sodium aurothiomalate, a hyaluronidase inhibitor.
Inhibition of in vitro fertilization of mouse gametes by sulfated sialic acid polymers.
Mechanism of infertility in male guinea pigs immunized with sperm PH-20.
Molecular cloning and characterization of rat sperm surface antigen 2B1, a glycoprotein implicated in sperm-zona binding.
Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg.
Phenotype and maturation rate of oocytes of chimaeric mice produced from two strains that differ in oocyte quality.
Prolonged exposure to hyaluronidase decreases the fertilization and development rates of fresh and cryopreserved mouse oocytes.
Relative efficacy of conventional sperm parameters and sperm penetration bioassay to assess bull fertility in vitro.
SPAM1 and PH-20 are two gene products expressed in bovine testis and present in sperm
SPAM1 Isoforms from Two Tissue Origins Are Differentially Localized Within Ejaculated Bull Sperm Membranes and Have Different Roles During Fertilization.
Sperm capacitation: a distant landscape glimpsed but unexplored.
Sperm penetration through cumulus mass and zona pellucida.
Sperm penetration through oocyte investments in mammals.
Sperm surface protein PH-20 is bifunctional: one activity is a hyaluronidase and a second, distinct activity is required in secondary sperm-zona binding.
Study of the Efficiency of Chemically Assisted Enucleation Method for Handmade Cloning in Goat (Capra hircus).
The dual functions of GPI-anchored PH-20: hyaluronidase and intracellular signaling.
The zona-free hamster oocyte penetration test: a simple procedure using a DNA fluorescent stain to detect the male pronucleus formation.
Ultrastructural evidence for an association between an oviductal glycoprotein and the zona pellucida of the golden hamster egg.
Ultrastructure of opossum oocyte investing coats and their sensitivity to trypsin and hyaluronidase.
Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg.
[Oocyte maturity and quality: value of intracytoplasmic sperm injection. Fertility of microinjected oocytes after in vitro maturation]
hyaluronoglucosaminidase deficiency
Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3.
hyaluronoglucuronidase deficiency
Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3.
Clinical and biochemical manifestations of hyaluronidase deficiency.
Infantile systemic hyalinosis in siblings: clinical report, biochemical and ultrastructural findings, and review of the literature.
Intracytoplasmic sperm injection for treatment of infertility due to acrosomal enzyme deficiency.
Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX.
[Congenital hyaluronidase deficiency]
[Glycogenosis type II (Pompe's disease) associated with alpha-amylase and hyaluronidase deficiency]
Hydatidiform Mole
[Blood hyaluronidase and hyaluronic acid concentration in hydatid mole and chorionepithelioma]
[Comparative evaluation of the serum and placental hyaluronidase activity in women with a physiological course of pregnancy and in those with hydatid mole and chorioepithelioma]
[Hyaluronidase content in the tissue of hydatidiform mole and chorionepithelioma]
Hydrocephalus
Tuberculous hydrocephalus: comparison of different treatments with regard to ICP, ventricular size and clinical outcome.
Use of hyaluronidase in the central nervous system.
Use of intrathecal hyaluronidase in the management of tuberculous meningitis with hydrocephalus.
Hyperalgesia
Extracellular matrix hyaluronan signals via its CD44 receptor in the increased responsiveness to mechanical stimulation.
[Experimental knee pain model in rats and analgesic effect of sodium hyaluronate (SPH)]
Hypercholesterolemia
A possible explanation of myxedema and hypercholesterolemia in hypothyroidism: control of lysosomal hyaluronidase and cholesterol esterase by thyroid hormones.
Effect of hyaluronidase on experimental hypercholesterolemia in rabbits and rats and atheromatosis in rabbits.
[The action of hyaluronidase on dietary hypercholesterolemia.]
Hyperemia
Heparin impairs glycocalyx barrier properties and attenuates shear dependent vasodilation in mice.
Hyaluronidase in chronic venous congestion of the legs.
Hyaluronidase treatment of coronary glycocalyx increases reactive hyperemia but not adenosine hyperemia in dog hearts.
[Hirudo medicinalis-leech applications in plastic and reconstructive microsurgery--a literature review]
Hyperhidrosis
Diffusion and short-term efficacy of botulinum toxin A after the addition of hyaluronidase and its possible application for the treatment of axillary hyperhidrosis.
Hyperinsulinism
Increased hyaluronan and hyaluronidase production and hyaluronan degradation in injured aorta of insulin-resistant rats.
Hyperlipidemias
Lipemia clearing by hyaluronidase, hyaluronate, and desoxycorticosterone, and its inhibition by cortisone, stress, and nephrosis.
Hyperoxaluria
[Hyaluronidase in experimental oxaluria.]
Hypersensitivity
A little-known phenomenon: allergic reaction to hyaluronidase.
A sting in the tale: cross reaction hypersensitivity to hyaluronidase.
Acute urticaria caused by the injection of goat-derived hyaluronidase.
Allergic reaction to hyaluronidase after a peribulbar injection.
Allergic reaction to hyaluronidase after retrobulbar anaesthesia: a case series and review.
Allergic reaction to hyaluronidase in cataract surgery.
Allergic reaction to hyaluronidase use after hyaluronic acid filler injection.
Allergic reaction to hyaluronidase: a rare cause of orbital inflammation after cataract surgery.
Allergic reactions to hyaluronidase in pain management -A report of three cases-.
Allergic reactions to hyaluronidase.
Anaphylactic shock caused by the epidurally-administered hyalurinidase.
Angioedema after ovine hyaluronidase injection for treating hyaluronic acid overcorrection.
Angioedema related to the use of hyaluronidase in cataract surgery.
Atypical case of hyaluronidase allergy with orbital compartment syndrome and visual loss.
Compressive optic neuropathy secondary to an allergic reaction to hyaluronidase.
Delayed allergic hypersensitivity to hyaluronidase during the treatment of granulomatous hyaluronic acid reactions.
Delayed allergic reaction to hyaluronidase: a rare sequel to cataract surgery.
Delayed allergic reaction to secondary administrated epidural hyaluronidase.
Glucocorticoids enhance interleukin-4 production to neo-antigen (hyaluronidase) in children immunocompromised with cytostatic drugs.
Hyaluronidase allergy after peribulbar anesthesia with orbital inflammation.
Hyaluronidase allergy mimicking orbital cellulitis.
Hyaluronidase allergy simulating expulsive choroidal hemorrhage.
Hyaluronidase allergy: a rare cause of periorbital inflammation.
Hyaluronidase and Hyaluronan in Insect Venom Allergy.
Hyaluronidase Caveats in Treating Filler Complications.
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
Hyaluronidase in Neuroplasty: A Review.
Hyaluronidase in the correction of hyaluronic acid-based fillers: a review and a recommendation for use.
Hyaluronidase in the Treatment of Allergy.
Hyaluronidase in treatment of human sterility; allergic reaction.
Hyaluronidase induced orbital pseudotumor as complication of retrobulbar anesthesia.
Hyaluronidase toxicity: a possible cause of post-operative periorbital inflammation.
Hyaluronidase: An overview of its properties, applications, and side effects.
Hypersensitivity reaction to hyaluronidase following peribulbar anesthesia: a case series.
Identification of a B-cell epitope of hyaluronidase, a major bee venom allergen, from its crystal structure in complex with a specific Fab.
IgE-mediated allergic reaction to hyaluronidase in paediatric oncological patients.
Immunotherapy with Commercial Venoms Is Efficacious for Anaphylactic Reactions to Vespa orientalis Stings.
Injected hyaluronidase reduces restylane-mediated cutaneous augmentation.
Orbital cellulitis vs allergic reaction to hyaluronidase as the cause of periorbital oedema.
Orbital Inflammation Secondary to a Delayed Hypersensitivity Reaction to Sub-Tenon's Hyaluronidase.
Raised intraocular pressure and orbital inflammation: A rare IgE-mediated allergic reaction to sub-Tenon's hyaluronidase.
Reassessing the role of hyaluronidase in yellow jacket venom allergy.
Recombinant hyaluronidase: response.
Subcutaneous rehydration: updating a traditional technique.
The evaluation of the common diagnostic methods of hypersensitivity for bee and yellow jacket venom by means of an in-hospital insect sting.
Type I allergic reaction to hyaluronidase during ophthalmic surgery.
Use of hyaluronidase in patients with bee allergy.
Use of hyaluronidase in the treatment of granulomatous hyaluronic acid reactions or unwanted hyaluronic acid misplacement.
Yellow jacket venom allergens, hyaluronidase and phospholipase: sequence similarity and antigenic cross-reactivity with their hornet and wasp homologs and possible implications for clinical allergy.
[Allergic angioedema after local dental anesthesia and a hyaluronidase-containing preanesthetic injection solution]
[Dynamics of the titers of antifibrinolysin, antistreptolysin-O, hyaluronidase activity and allergic reaction of the skin in patients with rheumatism]
[Effect of hyaluronidase on the course of allergic reactions.]
[EFFECT OF THE ENZYME HYALURONIDASE ON ALLERGIC REACTIONS DURING VACCINOTHERAPY OF BRUCELLOSIS.]
[Hyaluronidase in cytostatic therapy of ENT tumors]
[Hyaluronidase inhibitors in allergy patients.]
[Local and general hypersensitivity to hyaluronidase.]
[Use of hyaluronidase to correct hyaluronic acid injections in aesthetic medicine].
Hypersensitivity, Delayed
Delayed allergic reaction to secondary administrated epidural hyaluronidase.
Delayed hypersensitivity to hyaluronidase (Hyalasetrade mark) used during cataract surgery.
Orbital Inflammation Secondary to a Delayed Hypersensitivity Reaction to Sub-Tenon's Hyaluronidase.
Recombinant hyaluronidase: response.
The effects of areca catechu L extract on anti-inflammation and anti-melanogenesis.
[Immunomodulating action of hyaluronic acid and its hydrolysis products in health and in Staphylococcus infection]
Hypersensitivity, Immediate
Hyaluronidase: An overview of its properties, applications, and side effects.
Role of hyaluronidase in immediate hypersensitivity reaction.
Hypertension
Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
The relationship between aortic stiffness and serum hyaluronidase levels in patients with diabetes mellitus and hypertension.
Hypertension, Pulmonary
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology.
Hyperthyroidism
[Thyroid activity and hyaluronidase. Hyperthyroidism therapy with intravenous perfusion with congo red.]
Hypertriglyceridemia
Increased hyaluronan and hyaluronidase production and hyaluronan degradation in injured aorta of insulin-resistant rats.
Hyphema
[Effect of hyaluronidase on experimental hyphema.]
Hypothyroidism
A possible explanation of myxedema and hypercholesterolemia in hypothyroidism: control of lysosomal hyaluronidase and cholesterol esterase by thyroid hormones.
Hypoxia, Brain
Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase.
Infarction, Middle Cerebral Artery
Glycocalyx is critical for blood-brain barrier integrity by suppressing caveolin1-dependent endothelial transcytosis following ischemic stroke.
Infections
Alopecia in mice infected with murine cytomegalovirus (MCMV).
An intelligent vancomycin release system for preventing surgical site infections of bone tissues.
Antipneumococcus hyaluronidase activity in human serum; rise in titer following pneumococcus bacteremia with purulent infection of pleura and synovia.
Bacterial Hyaluronidase Promotes Ascending GBS Infection and Preterm Birth.
Biochemical and immunochemical characteristics of middle ear effusions in relation to bacteriological findings.
Effect of various digestive enzymes on the interaction of Toxoplasma gondii with macrophages.
Experimental streptococcal mastitis. X. The importance of a serum staphylococcal hyaluronidase inhibitor in infection of the cow.
Fungal contamination of hyaluronidase solution mimicking fungal joint infection: a preanalytical pitfall in synovial fluid analysis.
Further evidence for hyaluronidase activity of Treponema pallidum.
Glycoprotein analysis of porcine bronchoalveolar lavage fluid reveals potential biomarkers corresponding to resistance to Actinobacillus pleuropneumoniae infection.
Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection.
Hyaluronidase activity of bacteriophages of group A streptococci.
Hyaluronidase and infections of the hand.
Hyaluronidase enhances cell fusion and synthesis of viral DNA during infection with caprine arthritis encephalitis virus.
Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates.
Hyaluronidase in Clinical Isolates of Propionibacterium acnes.
Hyaluronidase is not essential for the lethality of Erysipelothrix rhusiopathiae infection in mice.
Hyaluronidase of bloodsucking insects and its enhancing effect on leishmania infection in mice.
Hyaluronidase production in Streptococcus milleri in relation to infection.
Immunological properties of hyaluronidases associated with temperate bacteriophages of group A streptococci.
INTESTINAL ADHESIONS-Present Status of Prevention and Treatment.
Loss of versican and production of hyaluronan in lung epithelial cells are associated with airway inflammation during RSV infection.
Molecular subtyping and characterization of bovine and human Streptococcus agalactiae isolates.
Mucopolysaccharides in suspensions of Treponema pallidum extracted from infected rabbit testes.
Protective effect of hyaluronidase and type-specific anti-M serum on experimental group A streptococcus infection in mice.
Release of hyaluronidase during in vitro development of Ascaris suum from the third to fourth larval stage.
Rubella and rheumatoid arthritis: hyaluronic acid and susceptibility of cultured rheumatoid synovial cells to viruses.
SEROLOGIC RESPONSE TO STREPTOCOCCAL HEMOLYSIN AND HYALURONIDASE IN STREPTOCOCCAL AND RHEUMATIC INFECTION.
Soft-Tissue Infection Caused by Streptococcus anginosus After Intramucosal Hyaluronidase Injection: A Rare Complication Related to Dermal Filler Injection.
Steroidal fraction of Carissa carandas L. inhibits microbial hyaluronidase activity by mixed inhibition mechanism.
Streptococcal pyrogenic exotoxin A, streptolysin O, exoenzymes, serotype and biotype profiles of Streptococcus pyogenes isolates from patients with toxic shock syndrome and other severe infections.
Studies on streptococcal hyaluronidase and antihyaluronidase. III. The production and cellular localization of hyaluronidase following streptococcal infection.
Suppression of hyaluronidase reduces invasion and establishment of Haemonchus contortus larvae in sheep.
The extracellular hyaluronidase gene (hylA) of Streptococcus pyogenes.
The influence of hyaluronidase on the course of experimental infections with certain bacteria and viruses.
The production of hyaluronidase by streptococci and its role in infection.
The role of hyaluronidase in experimental cryptococcal infections.
Treatment of experimental brain abscess. 2. Effects of combinations of hyaluronidase with antibiotics and dexamethasone.
[Action of cortisone associated with hyaluronidase on the experimental infection of guinea pig with BCG.]
[Data on a study of the biological properties of streptococcal hyaluronidase. II. On the effect of streptococcal hyaluronidase on the course of experimental streptococcal infection.]
[Effect of cortisone combined with hyaluronidase on experimental infection in the guinea pig induced by BCG.]
[Effect of hyaluronidase and infection with Hymenolepis nana on the course of larval ascariasis in laboratory animals]
[Effect of hyaluronidase on polysaccharides in experimental Candida albicans infection.]
[Effect of hyaluronidase on the course of Rickettsia typhi infections in laboratory animals.]
[Effect of hyaluronidase on Toxoplasma gondii infection in mice.]
[Effects of hyaluronidase on experimental rabies infection in mice.]
[Further experimental studies on the pathogenesis of cerebral listeriosis in the sheep. IV. The course of experimental Listeria monocytogenes infection in sheep following repeated listeria administration, change of culture temperature and duration, and additional hyaluronidase administration]
[Hyaluronidase activity and S-R dissociation of staphylococci isolated from surgical infections.]
[Hyaluronidase and hyaluronic acid in some signs of infection and immunity. VI. Effect of hyaluronidase and hyaluronic acid on the reactivity to a tetravaccine and preventive properties of immune sera.]
[Hyaluronidase and infections.]
[Hyaluronidase in infections with sanguicolous protozoa and in particular Plasmodium berghei; comparison with phenylhydrazine; role and significance of reticulocytosis.]
[Hyaluronidase in meningococcus]
[Immunomodulating action of hyaluronic acid and its hydrolysis products in health and in Staphylococcus infection]
[Influence of hyaluronidase and the infection with Hymenolepis nana on the level of vitamin C in rats with larval ascaridiasis]
[Results of the treatment of arterial angiopathy of the legs with a mixed intravenous infection of magnesium compound and hyaluronidase]
[The effect of hyaluronidase on infection of rats by different strains of Entamoeba histolytica]
[The pathogenetic aspects of the hyaluronidase activity of Proteus mirabilis]
[The pathogenicity factors of Streptococcus pneumoniae strains causing meningitis]
[The role of hyaluronidase in the occurrence of a generalized pneumococcal infection]
Infertility
Cytochemical detection of hyaluronidase activity in single human and mouse sperm by an improved substrate-film technique.
Endothelin-1 promotes human germinal vesicle-stage oocyte maturation by downregulating connexin-26 expression in cumulus cells.
Further observations of the value of hyaluronidase in the treatment of human infertility.
Hyaluronidase in treatment of human sterility.
Hyaluronidase in treatment of human sterility; allergic reaction.
Long-term contraceptive efficacy of vaccine of ovine follicle-stimulating hormone in male bonnet monkeys (Macaca radiata).
Rôle of hyaluronidase in human infertility.
The clinical evaluation of hyaluronidase in human infertility.
The role of hyaluronidase in human infertility; preliminary report.
The role of the hyaluronidase in human sterility.
[Hyaluronidase hydrotubation in sterility caused by the tubal factor.]
[Hyaluronidase of spermatozoa and sterility.]
Infertility, Female
[Female sterility caused by a tubal factor treated with tubal water insufflation with hyaluronidase & antibiotics.]
[Treatment of female sterility with cortisone, antibiotics and hyaluronidase]
[Treatment of female sterility with intra-tubal injections of hyaluronidase with antibiotics.]
[TREATMENT OF FEMALE STERILITY, CAUSED BY INFLAMMATORY PROCESSES IN THE UTERINE ADNEXA, WITH CORTISONE AND HYALURONIDASE COMBINED WITH ANTIBIOTICS.]
Infertility, Male
Effects of silencing epididymal vascular endothelial growth factor (VEGF) expression on hyaluronidase (HYD) activity in arsenic poisoning rats through downregulating VEGF receptor 2 (VEGFR2).
Experiments with hyaluronidase therapy in male infertility; preliminary report.
Fertilization, male infertility, and hyaluronidase.
The measurement of hyaluronidase activity in human spermatozoa by substrate slide assay and its clinical application.
Ulva lactuca methanolic extract improves oxidative stress-related male infertility induced in experimental animals.
Influenza, Human
Effect of cortisone and hyaluronidase on the production of hemagglutinin of influenza and vaccinia viruses in suspended cell cultures.
Pneumococcal surface protein A contributes to secondary Streptococcus pneumoniae infection after influenza virus infection.
[Effect of hyaluronidase on infectiosity of the influenza virus.]
[Hemostasis and hyaluronidase activity in influenza]
[Hyaluronic acid and hyaluronidase in influenza]
Insulin Coma
Hyaluronidase as an adjuvant in insulin shock therapy.
Hyaluronidase in insulin coma therapy.
Measurements of effects of hyaluronidase in insulin coma treatment.
The use of hyaluronidase with insulin in insulin coma therapy.
Use of hyaluronidase in insulin coma therapy.
Use of hyaluronidase in insulin coma.
[Considerations on the facilitating action of hyaluronidase in insulin coma.]
[Insulin coma & hyaluronidase.]
[Insulin coma induced by reduced doses of insulin combined with hyaluronidase.]
Insulin Resistance
CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high fat-fed C57BL/6 mice.
Hyaluronan Accumulates with High Fat Feeding and Contributes to Insulin Resistance.
Increased hyaluronan and hyaluronidase production and hyaluronan degradation in injured aorta of insulin-resistant rats.
[Insulin sensitivity in schizophrenia; insulin economy with hyaluronidase.]
Intervertebral Disc Displacement
MR of disc protrusion engendered by infectious spondylitis.
Intestinal Obstruction
Lecithinase and hyaluronidase in experimental intestinal obstruction.
Intussusception
Hyaluronidase assisted reduction of intestinal intussusception; a novel application.
Iritis
Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage.
Joint Diseases
Chondroitin - application in the treatment of degenerative joint disease.
Expression and activity of articular cartilage hyaluronidases.
Hyaluronidase in Joint Disease.
Hyaluronidase therapy of inflammatory and degenerative joint diseases.
Inhibition of hyaluronidase activity by select sorghum brans.
[Clinical studies of intra-articular injections of Arteparon. Retrospective study following the treatment of 754 patients]
[Experiences with hyaluronidase in chronic arthropathies.]
[Experiences with hyaluronidase in-the treatment of chronic arthropathy of the temporomandibular joint.]
[Hyaluronic acid. Usefulness and perspectives of its serum assay]
Keloid
A comparative study of various modalities in the treatment of keloids.
A Review of Current Keloid Management: Mainstay Monotherapies and Emerging Approaches.
Altered expression of hyaluronan synthase and hyaluronidase mRNA may affect hyaluronic acid distribution in keloid disease compared with normal skin.
The treatment of keloids with a combination of hyaluronidase and kutapressin.
Treatment of extensive, recalcitrant keloids using a combination of intralesional cryosurgery, triamcinolone, 5-fluorouracil and hyaluronidase.
Treatment of keloids with hyaluronidase.
[Hyaluronidase therapy of keloid.]
[Local treatment of keloid with hyaluronidase.]
[Therapy of fresh keloids with hyaluronidase.]
[Treatment of keloids with local infiltration of hyaluronidase combined with radiotherapy.]
Keratitis
Bacterial enzyme in viral infections: a new concept. The possible role of hyaluronidase in herpes simplex virus keratitis.
Keratitis, Herpetic
[HYALURONIDASE IN THE TREATMENT OF HERPETIC KERATITIS.]
Keratoacanthoma
Non-immunologic enhancement and regression of self-healing squamous cell carcinoma (keratoacanthoma)--ground substance and inflammation.
Keratoconus
Hyaluronidase (Vitrase)--ISTA: hyaluronidase--ISTA pharmaceuticals.
Kidney Calculi
Hyaluronidase and renal calculi in poliomyelitis.
KIDNEY stones, urinary colloids and hyaluronidase.
[Hyaluronidase in prevention of renal calculi.]
Kidney Diseases
Can Plasma Hyaluronan and Hyaluronidase Be Used As Markers of the Endothelial Glycocalyx State in Patients with Kidney Disease?
Lacrimal Duct Obstruction
Nasolacrimal Duct Obstruction Following Hyaluronic Acid Rejuvenation of the Tear Trough.
Larva Migrans
Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans.
Laryngeal Neoplasms
Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors.
PH20: a novel tumor marker for laryngeal cancer.
Latent Infection
Glycoprotein analysis of porcine bronchoalveolar lavage fluid reveals potential biomarkers corresponding to resistance to Actinobacillus pleuropneumoniae infection.
Leg Ulcer
Local ambulatory treatment of chronic leg ulcers with hyaluronidase, plasminogen, and antibiotics.
Leiomyoma
[Extracts of the uterus and uterine fibroma blocking the intracutaneous diffusion of hyaluronidase.]
Leishmaniasis
Hyaluronidase of bloodsucking insects and its enhancing effect on leishmania infection in mice.
Leprosy
[Relation between host resistance and disease type in mouse leprosy. 2. Influence of hyaluronidase on the onset of mouse leprosy.]
Leukemia
ReCAP: Detection of Potentially Avoidable Harm in Oncology From Patient Medical Records.
Leukemia, Lymphocytic, Chronic, B-Cell
Subcutaneous Rituximab in Follicular Lymphoma, Chronic Lymphocytic Leukemia, and Diffuse Large B-Cell Lymphoma.
Subcutaneous rituximab with recombinant human hyaluronidase in the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Lipodystrophy
Effect of ultrasound and hyaluronidase on gynoid lipodystrophy type II - An ultrasonography study.
Listeriosis
[Further experimental studies on the pathogenesis of cerebral listeriosis in the sheep. IV. The course of experimental Listeria monocytogenes infection in sheep following repeated listeria administration, change of culture temperature and duration, and additional hyaluronidase administration]
Liver Cirrhosis
Hepatoprotection of Herpetospermum caudigerum Wall. against CCl4-induced liver fibrosis on rats.
Traditional Chinese medicine Bao Gan Ning increase phosphorylation of CREB in liver fibrosis in vivo and in vitro.
[Efficacy Observation of Yiguanjian Decoction Combined Adefovir Dipivoxil Tablet in Treating HBeAg Negative Chronic Viral Hepatitis B Active Compensated Liver Cirrhosis Patients].
Liver Diseases
Mucolytic enzyme systems. X. Serum hyaluronidase inhibitor in liver disease.
Liver Neoplasms
Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery.
Liver Neoplasms, Experimental
Biosynthesis of albumin via a precursor protein in Morris hepatoma 5123tc.
Lung Diseases
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology.
[Activity of native and dextran-modified hyaluronidase in in vitro and in vivo systems]
Lung Injury
Changes in lung hyaluronidase activity associated with lung growth, injury and repair.
Hyaluronidase modulates bleomycin-induced lung injury detected noninvasively in small rodents by radial proton MRI.
[Effect of hyaluronidase on porcine pancreatic elastase-induced lung injury]
Lung Neoplasms
Mucolytic action of hyaluronidase on sputum for the cytological diagnosis of lung cancer.
Lymphedema
Hyaluronidase treatment of acute lymphedema in a mouse tail model.
Therapeutic effects of hyaluronidase on acquired lymphedema using a newly developed mouse limb model.
Use of hyaluronidase by iontophoresis in treatment of lymphedema.
[A case of congenital lymphedema treated with hyaluronidase and ACTH.]
Lymphocytic Choriomeningitis
Lymphocytic choriomeningitis virus. VII. Structural alterations of the virion by treatment with proteolytic enzymes without loss of infectivity.
Lymphoma
Hyaluronidase activity in murine leukaemia & lymphoma.
Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent.
Radiation-induced lymphoblastic lymphomas/leukemias and sarcomas of mice express conserved, immunogenic 44-kilodalton oncofetal antigen.
Lymphoma, B-Cell
Subcutaneous Rituximab in Follicular Lymphoma, Chronic Lymphocytic Leukemia, and Diffuse Large B-Cell Lymphoma.
Lymphoma, Follicular
Subcutaneous administration of rituximab (MabThera) and trastuzumab (Herceptin) using hyaluronidase.
Subcutaneous Rituximab in Follicular Lymphoma, Chronic Lymphocytic Leukemia, and Diffuse Large B-Cell Lymphoma.
Lymphoma, Large B-Cell, Diffuse
Subcutaneous Rituximab in Follicular Lymphoma, Chronic Lymphocytic Leukemia, and Diffuse Large B-Cell Lymphoma.
Lymphoma, Non-Hodgkin
Expression of HYAL2 mRNA, hyaluronan and hyaluronidase in B-cell non-Hodgkin lymphoma: relationship with tumor aggressiveness.
Subcutaneous rituximab with recombinant human hyaluronidase in the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Macroglossia
Posttraumatic macroglossia complicated by hyaluronidase injection.
Macular Edema
Effect of hyaluronidase on the incidence of cystoid macular edema.
Effect of retrobulbar hyaluronidase on pseudophakic cystoid macular edema.
Factors affecting pseudophakic cystoid mascular edema: five randomized trials.
Mastitis
Experimental streptococcal mastitis. X. The importance of a serum staphylococcal hyaluronidase inhibitor in infection of the cow.
Hyaluronidase production in vitro by streptococci isolated from bovine mastitis cases.
The use of hyaluronidase in certain cases of mastitis; a preliminary report.
[Comparative research on the capacity of mastitis Staphylococci and pyogenic staphylococci from other purulent processes to produce hyaluronidase.]
[Intramammary injection treatment of puerperal mastitis with live streptococci and hyaluronidase.]
Mastocytoma
[Mastocytoma and urticaria pigmentosa; attempts at injection in situ of hyaluronidase.]
Melanoma
Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumor activity of RNase A.
Efficient PD-L1 gene silence promoted by hyaluronidase for cancer immunotherapy.
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Hyaluronan synthase 3 (HAS3) overexpression downregulates MV3 melanoma cell proliferation, migration and adhesion.
Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells.
Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice.
Hyaluronidase significantly enhances the efficacy of regional vinblastine chemotherapy of malignant melanoma.
Investigations into hyaluronic acid and hyaluronidase in the subretinal fluid in retinal detachment, partly due to ruptures and partly secondary to malignant choroidal melanoma; preliminary report suggesting a new hypothesis concerning the pathogenesis of retinal detachment.
Pharmaceutical approval update.
Pharmacokinetics and tissue distribution of bovine testicular hyaluronidase and vinblastine in mice: an attempt to optimize the mode of adjuvant hyaluronidase administration in cancer chemotherapy.
The growth rate of two transplantable murine tumors, 3LL lung carcinoma and B16F10 melanoma, is influenced by Hyal-1, a locus determining hyaluronidase levels and polymorphism.
[Hyaluronidase content of malignant melanoma]
Melanoma, Experimental
Hyaluronidase and collagenase increase the transfection efficiency of gene electrotransfer in different murine tumors.
Meningioma
Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase.
Novel immunogenic antigen homologous to hyaluronidase in meningioma.
Meningitis
Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis.
Experimental pneumococcal meningitis in mice: a model of intranasal infection.
IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis.
Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis.
[On the formation of hyaluronidase by Leptospira, with reference to meningitis and the hemoencephalic barrier.]
[The role of hyaluronidase in the occurrence of a generalized pneumococcal infection]
Meningitis, Pneumococcal
A study of pathogenic factors of Streptococcus pneumoniae strains causing meningitis.
IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis.
Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis.
Meningococcal Infections
[Natural reproduction of all stages of a generalized meningococcal infection in mice]
Meningoencephalitis
[The role of hyaluronidase in the occurrence of a generalized pneumococcal infection]
Meningomyelocele
Use of hyaluronidase in the central nervous system.
Mesothelioma
Diagnostic histochemical and immunohistochemical studies in malignant mesothelioma.
Differentiation of adenocarcinoma of the lung from mesothelioma. Periodic acid-Schiff, monoclonal antibodies B72.3, and Leu M1.
Immunohistological study of malignant diffuse mesotheliomas of the pleura.
Pleural mesothelioma: an approach to diagnostic problems.
The cytologic diagnosis of mesothelioma.
[Intrapleural injection of hyaluronidase in mesothelioma]
[Malignant mesothelioma. Retrospective study of 16 cases]
Mesothelioma, Malignant
Diffuse malignant peritoneal mesothelioma in a young woman with a high serum level of CA125.
Hyaluronic acid content of effusions as a diagnostic aid for malignant mesothelioma.
[Normal-sized ovary carcinoma syndrome: histopathological analysis of 14 cases]
Microstomia
Hyaluronidase injections for treatment of symptomatic pansclerotic morphea-induced microstomia.
Hyaluronidase Treatment of Scleroderma-Induced Microstomia.
Prosthetic Management of Microstomia with Customized Dynamic Splint.
Mucolipidoses
Hyaluronidase in human somatic tissues and urine: polymorphism and the activity in diseases.
Plasma hyaluronidase activity in mucolipidoses II and III: marked differences from other lysosomal enzymes.
Mucopolysaccharidoses
Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX.
Screening Mucopolysaccharidosis Type IX in Patients with Juvenile Idiopathic Arthritis.
Serum hyaluronidase aberrations in metabolic and morphogenetic disorders.
Urinary hyaluronidase activity in mucopolysaccharidosis.
[Increase of the serum activity of hyaluronidase, beta glucuronidase and beta acetylglucosaminidase in mucopolysaccharidoses]
Mucopolysaccharidosis I
Hyaluronidase and sulfatase deficiency in Hurler's syndrome.
Muscle Hypotonia
[Comparison of the effect of 0.75% bupivacaine with 0.75% bupivacaine/2% mepivacaine in retrobulbar anesthesia and the effect of adding hyaluronidase]
Muscle Spasticity
New Treatment Approaches on the Horizon for Spastic Hemiparesis.
[The prospects of use of hyaluronidase in obstetrics and gynecology. The use of the new Soviet preparation lidase with spasmolytics in rigid and spastic states of the cervix uteri.]
Myocardial Infarction
An overview of the clinical trials of agents (other than beta-blockers) that potentially limit myocardial infarct size.
Analysis of the geometry of myocardial infarct size reduction with hyaluronidase.
CLS 2210, hyaluronidase and the cardiac lymphatic system.
Early disappearance of lymphatics draining ischemic myocardium in the dog.
Effect of a highly purified hyaluronidase preparation (GL enzyme) on electrocardiographic changes in acute myocardial infarction.
Effect of hyaluronidase (GL enzyme) on mortality after myocardial infarction.
Effect of hyaluronidase and methylprednisolone on myocardial function, glucose metabolism, and coronary flow in the isolated ischemic rat heart.
Effect of hyaluronidase on mortality and morbidity in patients with early peaking of plasma creatine kinase MB and non-transmural ischaemia. Multicentre investigation for the limitation of infarct size (MILIS).
Effects of early administration of a highly purified hyaluronidase preparation (GL enzyme) on myocardial infarct size.
Effects of hyaluronidase administration on myocardial ischemic injury in acute infarction. A preliminary study in 24 patients.
Effects of hyaluronidase on reducing myocardial infarct size in a baboon model of ischemia-reperfusion injury.
Effects of pharmacological intervention on infarct size following induced myocardial infarction in rats.
Efforts to limit the size of myocardial infarcts.
Electrocardiographic and clinical criteria for recognition of acute myocardial infarction based on analysis of 3,697 patients.
Evaluation of the hemodynamic effects of hyaluronidase in patients with acute myocardial infarction.
Failure of hyaluronidase to alter the early course of acute myocardial infarction in pigs.
Favorable effects of hyaluronidase on electrocardiographic evidence of necrosis in patients with acute myocardial infarction.
Glycosaminoglycan metabolism following acute myocardial infarction and the effects of intravenous hyaluronidase therapy.
Hyaluronidase can be used to reduce interstitial edema in the presence of heparin.
Hyaluronidase in the management of myocardial infarction.
Hyaluronidase therapy for acute myocardial infarction: results of a randomized, blinded, multicenter trial. MILIS Study Group.
Importance of the source of hyaluronidase preparations in determining protective effect on ischemic heart muscle in acute myocardial infarction.
Interventions that potentially limit myocardial infarct size: overview of clinical trials.
Intravenous Hyaluronidase for Visual Loss Secondary to Filler Injection: A Novel Therapeutic Approach.
Intravenous hyaluronidase therapy for myocardial infarction in man: double-blind trial to assess infarct size limitation.
Intravenous injection of hyaluronidase in acute myocardial infarction: preliminary report of clinical and experimental observations.
Myocardial infarct size. Part 2. Comparison of anti-infarct effects of beta-blockade, glucose-insulin-potassium, nitrates, and hyaluronidase.
Myocardial infarction treated with two lymphagogues, calcium dobesilate (CLS 2210) and hyaluronidase: a coded, placebo-controlled animal study.
Permeability factor contaminating hyaluronidase preparations.
Salvage of ischemic myocardium by CLS 2210 in the dog: a preliminary double-blind study.
The co-operative action of hyaluronidase and urokinase on the isoproterenol-induced myocardial infarction in rats.
The effect of hyaluronidase and dimethyl sulfoxide (DMSO) on experimental skin flap survival.
The effects of a highly purified hyaluronidase preparation on experimental myocardial infarction in the rat.
THE EFFECTS OF LARGE INTRAVENOUS DOSES OF HYDROCORTISONE OR HYALURONIDASE ON THE ELECTROCARDIOGRAPHIC PATTERN OF ACUTE MYOCARDIAL INFARCTION. A COMPARATIVE CLINICAL AND EXPERIMENTAL STUDY.
The use of hyaluronidase and hydrocortisone in the reduction of myocardial infarct size following coronary occlusion. Experimental and clinical observations.
The use of hyaluronidase in acute myocardial infarction.
Use of hyaluronidase in myocardial infarction.
[EFFECT OF HIGH DOSES OF GLUCOCORTCOIDS AND HYALURONIDASE, ADMINISTERED BY INTRAVENOUS ROUTE, ON ELECTROCARDIOGRAPHIC CHANGES IN ACUTE MYOCARDIAL INFARCT. I. EXPERIMENTAL STUDY.]
[EFFECT OF HIGH DOSES OF GLUCOCORTICOIDS AND HYALURONIDASE, ADMINISTERED BY INTRAVENOUS ROUTE, ON ELECTROCRADIOGRAPHIC CHANGES IN ACUTE MYOCARDIAL INFARCT. II. CLINICAL STUDY.]
[Effect of hyaluronidase on morphological changes in the myocardium in experimental myocardial infarct]
[Effect of hyaluronidase on the interrelations of the stromal elements of the myocardium in the healing of experimental myocardial infarct]
[Electron-microscopic study of changes in the myocyte ultrastructure under the effect of hyaluronidase in experimental myocardial infarct]
[Hyaluronidase treatment of acute myocardial infarct]
[Pharmacologic limitation of the size of the myocardial infarction (excluding thrombolysis)]
[RHYTHM AND CONDUCTION DISORDERS IN ACUTE MYOCARDIAL INFARCTION TREATED WITH HYALURONIDASE.]
[Study of the effect of hyaluronidase on the course of myocardial infarct]
[The use of hyaluronidase in recent myocardial infarct. Electrocardiographic study.]
[Use of mannitol, hyaluronidase and glucose-insulin-potassium in the treatment of acute myocardial infarction (author's transl)]
Myocardial Ischemia
Accumulation of hyaluronan and tissue edema in experimental myocardial infarction.
Decrease in acute myocardial ischemia by hyaluronidase in isolated, perfused, rabbit hearts.
Effect of hyaluronidase during the early phase of acute myocardial ischemia: an ultrastructural and morphometric analysis.
Effects of hyaluronidase on reducing myocardial infarct size in a baboon model of ischemia-reperfusion injury.
Mechanism of action of hyaluronidase in decreasing myocardial ischemia post coronary occlusion in the isolated perfused rabbit heart.
Myofascial Pain Syndromes
Comparison of the Effect of Bicarbonate, Hyaluronidase, and Lidocaine Injection on Myofascial Pain Syndrome.
Effect of Hyaluronidase Addition to Lidocaine for Trigger Point Injection in Myofascial Pain Syndrome.
Myopia
Subconjunctival hyaluronidase injection producing temporary myopia.
Myotoxicity
A comparison of mepivacaine versus lidocaine for episcleral (sub-tenon's) block for cataract surgery in an ambulatory setting.
Cross-reactivity and neutralization of Indian King cobra (Ophiophagus hannah) venom by polyvalent and monovalent antivenoms.
Doxorubicin chemomyectomy in orbicularis oculi: increasing drug infiltration at the injection site.
Isolation and characterization of hyaluronidase a "spreading factor" from Indian cobra (Naja naja) venom.
Myxedema
A possible explanation of myxedema and hypercholesterolemia in hypothyroidism: control of lysosomal hyaluronidase and cholesterol esterase by thyroid hormones.
Injected Hyaluronidase Reduces the Volume of Exogenous Hyaluronate Fillers in Mice and Results in Clinical Improvement in a Patient with Pretibial Myxedema.
Local injections of a preparation of hyaluronidase in the treatment of localized (pretibial) myxedema.
Periorbital myxedema treated with intralesional hyaluronidase.
Pretibial myxedema successfully treated with intralesional hyaluronidase.
Pretibial myxedema treated with intralesional hyaluronidase and triamcinolone.
Successful Treatment of Scalp Myxedema with Injected Hyaluronidase: A Case Report.
The treatment of localized (pretibial) myxedema with hyaluronidase.
[Local myxedema treated with hyaluronidase.]
[Presence of hyaluronidase inhibitor in a case of myxedema circumscriptum pretibiale (author's transl)]
Myxoma
Intramuscular myxoma--a clinicopathological study of twenty-three cases.
Nasal Polyps
Presence of hyaluronidase isoforms in nasal polyps.
Neoplasm Metastasis
Accelerated genetic destabilization and dormancy: two distinct causes of resistance in metastatic cells; clinical magnitude, therapeutic approaches.
Ascorbic acid in the prevention and treatment of cancer.
Association of hyaluronidase and breast adenocarcinoma invasiveness.
Decreasing the metastatic potential in cancers--targeting the heparan sulfate proteoglycans.
Effect of hyaluronidase on the pharmacokinetics of free and total platinum species after intra-arterial Cisplatin in refractory patients with colorectal liver metastases.
Emerging roles for hyaluronidase in cancer metastasis and therapy.
Erratum to: Effect of Hyaluronidase on the Pharmacokinetics of Free and Total Platinum Species after Intra-Arterial Cisplatin in Refractory Patients with Colorectal Liver Metastases.
Folic acid-modified Exosome-PH20 enhances the efficiency of therapy via modulation of the tumor microenvironment and directly inhibits tumor cell metastasis.
HA-HAase urine test. A sensitive and specific method for detecting bladder cancer and evaluating its grade.
Human breast-cancer metastasis formation in a nude-mouse model: studies of hyaluronidase, hyaluronan and hyaluronan-binding sites in metastatic cells.
Hyalase-Mediated Cascade Degradation of a Matrix Barrier and Immune Cell Penetration by a Photothermal Microneedle for Efficient Anticancer Therapy.
Hyaluronan mediates adhesion of metastatic colon carcinoma cells.
Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling.
Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death.
Hyaluronidase activity in gynaecological cancer tissues with different metastatic forms.
Hyaluronidase expression induces prostate tumor metastasis in an orthotopic mouse model.
Hyaluronidase is more elevated in human brain metastases than in primary brain tumours.
Hyaluronidase, the fundamental cause of foetal growth.
Hyaluronidases in tissue invasion.
Identification of bladder tumor-derived hyaluronidase: its similarity to HYAL1.
Increased hyaluronidase expression in more aggressive prostate adenocarcinoma.
Increased hyaluronidase levels in breast tumor metastases.
Inhibition of hyaluronidase by dextran sulfate and its possible application in anticancer treatment.
Kinetic analysis of hyaluronidase activity using a bioactive MRI contrast agent.
Phenolic constituents of the Bangladeshi medicinal plant Pothos scandens and their anti-estrogenic, hyaluronidase inhibition, and histamine release inhibitory activities.
Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling.
Shell-Crosslinked Hyaluronic Acid Nanogels for Live Monitoring of Hyaluronidase Activity In Vivo.
Strategies by which WWOX-deficient metastatic cancer cells utilize to survive via dodging, compromising, and causing damage to WWOX-positive normal microenvironment.
Stromal and epithelial expression of tumor markers hyaluronic acid and HYAL1 hyaluronidase in prostate cancer.
Theranostic size-reducible and no donor conjugated gold nanocluster fabricated hyaluronic acid nanoparticle with optimal size for combinational treatment of breast cancer and lung metastasis.
[Effects of adjuvant hyaluronidase in tumors refractory to chemotherapy. Review of the literature and pharmacokinetics of cisplatin after regional administration in animals and humans]
[Hyaluronic acid and hyaluronidase. 2 new bladder carcinoma markers]
[Hyaluronidase as a factor in tumor metastasis.]
Neoplasms
A cellular/intranuclear dual-targeting nanoplatform based on gold nanostar for accurate tumor photothermal therapy.
A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting.
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
A Dynamic 3D Tumor Spheroid Chip Enables More Accurate Nanomedicine Uptake Evaluation.
A hyaluronic acid fluorescent hydrogel based on fluorescence resonance energy transfer for sensitive detection of hyaluronidase.
A Hyaluronidase and a Polysaccharide from Tumours.
A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells.
A hyaluronidase/ATP tandem stimuli-responsive supramolecular assembly.
A multifunctional ternary Cu(II)-carboxylate coordination polymeric nanocomplex for cancer thermochemotherapy.
A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors.
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis.
A novel surface-enhanced Raman scattering-based ratiometric approach for detection of hyaluronidase in urine.
A randomized controlled trial of local injections of hyaluronidase versus placebo in cancer patients receiving subcutaneous hydration.
A self-delivery system based on an amphiphilic proapoptotic peptide for tumor targeting therapy.
A Sequential Target-Responsive Nanocarrier with Enhanced Tumor Penetration and Neighboring Effect In Vivo.
A simple assay for hyaluronidase activity using fluorescence polarization.
A Tumor Microenvironment Destroyer for Efficient Cancer Suppression.
A tumor-targeted theranostic nanomedicine with strong absorption in the NIR-II biowindow for image-guided multi-gradient therapy.
Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.
Acid mucopolysaccharides in mammary tumors of dogs.
Actin-resistant DNAse I Expression From Oncolytic Adenovirus Enadenotucirev Enhances Its Intratumoral Spread and Reduces Tumor Growth.
Activatable hyaluronic acid nanoparticle as a theranostic agent for optical/photoacoustic image-guided photothermal therapy.
Activation and inhibition of human cancer cell hyaluronidase by proteins.
Adenomatoid tumor of the ovary: an immunohistochemical and ultrastructural study.
Adjuvant therapy with hyaluronidase prior to excision of dermatofibrosarcoma protuberans.
An enhanced chemotherapeutic effect facilitated by sonication of MSN.
An immune cocktail therapy to realize multiple boosting of the cancer-immunity cycle by combination of drug/gene delivery nanoparticles.
Analysis of glycosaminoglycan-degrading enzymes by substrate gel electrophoresis (zymography).
Analysis of tumor-infiltrating gamma delta T cells in rectal cancer.
Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor.
Antioxidant, Anti-Inflammatory, and Cytotoxic Activity of Extracts from Some Commercial Apple Cultivars in Two Colorectal and Glioblastoma Human Cell Lines.
Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer.
Ascorbic acid in the prevention and treatment of cancer.
Association of elevated levels of hyaluronidase, a matrix-degrading enzyme, with prostate cancer progression.
Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis.
Association of hyaluronidase and breast adenocarcinoma invasiveness.
Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors.
Basement membrane alterations after treatment with trypsin, hyaluronidase or collagenase.
Bio-stimuli-responsive multi-scale hyaluronic acid nanoparticles for deepened tumor penetration and enhanced therapy.
Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane.
Biodegradable cationic nanoparticles loaded with an anticancer drug for deep penetration of heterogeneous tumours.
Bioresponsive functional nanogels as an emerging platform for cancer therapy.
Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion.
Cancer resistance, carcinogenesis and ground substance viscosity.
Cancer therapy by intra-arterial methotrexate infusion. Protection of mucous membranes by topically applied citrovorum factor with hyaluronidase.
Cationic Conjugated Polymer/Hyaluronan-Doxorubicin Complex for Sensitive Fluorescence Detection of Hyaluronidase and Tumor-Targeting Drug Delivery and Imaging.
CD44-dependent lymphoma cell dissemination: a cell surface CD44 variant, rather than standard CD44, supports in vitro lymphoma cell rolling on hyaluronic acid substrate and its in vivo accumulation in the peripheral lymph nodes.
CD44-Targeted and Enzyme-Responsive Photo-Cross-Linked Nanogels with Enhanced Stability for In Vivo Protein Delivery.
Characterization of two cell lines, derived from two malignant fibrous histiocytomas.
Chemotherapy and serum hyaluronic acid levels in malignant peritoneal mesothelioma.
Clinical Trials Targeting the Stroma in Pancreatic Cancer: A Systematic Review and Meta-Analysis.
Coadministration of iRGD with Multistage Responsive Nanoparticles Enhanced Tumor Targeting and Penetration Abilities for Breast Cancer Therapy.
Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck.
Comparison of the prognostic potential of hyaluronic acid, hyaluronidase (HYAL-1), CD44v6 and microvessel density for prostate cancer.
Concurrent expression of hyaluronan biosynthetic and processing enzymes promotes growth and vascularization of prostate tumors in mice.
Construction and application of a liver cancer-targeting drug delivery system based on core-shell gold nanocages.
Construction of multifunctional porous silica nanocarriers for pH/enzyme-responsive drug release.
Cross-talk between human monocytes and cancer cells during reactive oxygen intermediates generation: the essential role of hyaluronan.
Current treatment landscape and emerging therapies for pancreatic cancer.
Decreasing hyaluronic acid combined with drug-loaded nanoprobes improve the delivery and efficacy of chemotherapeutic drugs for pancreatic cancer.
Decreasing the metastatic potential in cancers--targeting the heparan sulfate proteoglycans.
Degradation of tumour stromal hyaluronan by small extracellular vesicle-PH20 stimulates CD103+ dendritic cells and in combination with PD-L1 blockade boosts anti-tumour immunity.
Demonstration of a new hyaluronidase inhibitor in serum of cancer patients.
Depolymerization of hyaluronan using PEGylated human recombinant hyaluronidase promotes nanoparticle tumor penetration.
Detection of bladder tumours: role of cytology, morphology-based assays, biochemical and molecular markers.
Detection of hyaluronidase activity using fluorescein labeled hyaluronic acid and Fluorescence Correlation Spectroscopy.
Development of the hyaluronidase activity assay as a cancer screening test.
Difference of hyaluronidase produced by human tumor cell lines with hyaluronidase present in human serum as revealed by zymography.
Differential selectivity of hyaluronidase inhibitors toward acidic and basic hyaluronidases.
Double-layered hyaluronic acid/stearic acid-modified polyethyleneimine nanoparticles encapsulating (-)-gossypol: a nanocarrier for chiral anticancer drugs.
Double-Targeting Explosible Nanofirework for Tumor Ignition to Guide Tumor-Depth Photothermal Therapy.
Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery.
Dual-responsive nanohybrid based on degradable silica-coated gold nanorods for triple-combination therapy for breast cancer.
Effect of anticoagulants on the plasma hyaluronidase activities.
Effect of collagenase and hyaluronidase on free and anomalous diffusion in multicellular spheroids and xenografts.
Effect of enzymatic disaggregation on proliferation of human tumor cells in soft agar.
Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells.
Effect of Matrix-Modulating Enzymes on The Cellular Uptake of Magnetic Nanoparticles and on Magnetic Hyperthermia Treatment of Pancreatic Cancer Models In Vivo.
Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma.
Effects of hyaluronidase on doxorubicin penetration into squamous carcinoma multicellular tumor spheroids and its cell lethality.
Efficacy of hyaluronic acid on intervertebral disc inflammation: An in vitro study using notochordal cell lines and human disc cells.
Efficient PD-L1 gene silence promoted by hyaluronidase for cancer immunotherapy.
Elevated hyaluronan concentration without hyaluronidase activation in malignant epithelial ovarian tumors.
Elimination of autofluorescence in fluorescence correlation spectroscopy using the AzaDiOxaTriAngulenium (ADOTA) fluorophore in combination with time-correlated single-photon counting (TCSPC).
Emerging roles for hyaluronidase in cancer metastasis and therapy.
Engineered Targeted Hyaluronic Acid-Glutathione-Stabilized Gold Nanoclusters/Graphene Oxide-5-Fluorouracil as a Smart Theranostic Platform for Stimulus-Controlled Fluorescence Imaging-Assisted Synergetic Chemo/Phototherapy.
Engineering the surface of prostate tumor cells and hyaluronan/chitosan multilayer films to modulate cell-substrate adhesion properties.
Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin.
Enhancement of tumorigenic potential in virgin mice of a pregnancy-dependent mouse mammary tumor (TPDMT-4) by enzymatic cell dissociation.
Enzyme-responsive mesoporous silica nanoparticles for tumor cells and mitochondria multistage-targeted drug delivery.
Enzyme/pH-triggered anticancer drug delivery of chondroitin sulfate modified doxorubicin nanocrystal.
Establishment and characterization of a cell line from a malignant fibrous histiocytoma of bone developing in a patient with multiple fibrous dysplasia.
Evaluation of in vitro and in vivo antitumor effects of gambogic acid-loaded layer-by-layer self-assembled micelles.
Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus.
EXPERIMENTAL INVESTIGATION ON INFLUENCE OF HYALURONIDASE ON SPREAD OF TRANSPLANTED TUMOURS.
Expression and regulation patterns of hyaluronidases in small cell lung cancer and glioma lines.
Expression of HYAL2 mRNA, hyaluronan and hyaluronidase in B-cell non-Hodgkin lymphoma: relationship with tumor aggressiveness.
Expression of Hyaluronan Synthases (HAS1-3) and Hyaluronidases (HYAL1-2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content.
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Expression of PH-20 in normal and neoplastic breast tissue.
Expression of tumor markers hyaluronic acid and hyaluronidase (HYAL1) in head and neck tumors.
Expression profile of hyaluronidase mRNA transcripts in the kidney and in renal cells.
Extracellular Matrix Component Shelled Nanoparticles as Dual Enzyme-Responsive Drug Delivery Vehicles for Cancer Therapy.
Extracellular matrix remodeling in vivo for enhancing tumor-targeting efficiency of nanoparticle drug carriers using the pulsed high intensity focused ultrasound.
Factors Influencing Resilience among Korean adolescents and young adult survivors of childhood cancer.
Failure of hyaluronidase to increase in invasiveness of neoplasms.
Folic acid-modified Exosome-PH20 enhances the efficiency of therapy via modulation of the tumor microenvironment and directly inhibits tumor cell metastasis.
Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p.
Glioma-associated hyaluronan induces apoptosis in dendritic cells via inducible nitric oxide synthase: implications for the use of dendritic cells for therapy of gliomas.
Glucocorticoids enhance interleukin-4 production to neo-antigen (hyaluronidase) in children immunocompromised with cytostatic drugs.
Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy.
HAase-sensitive dual-targeting irinotecan liposomes enhance the therapeutic efficacy of lung cancer in animals.
Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy.
Highly enhanced cancer immunotherapy by combining nanovaccine with hyaluronidase.
Host-tumor relationship XXXIII. Inhibitor of hyaluronidase in blood serum of cancer patients.
Host-tumor relationship. XXXIV. Hyaluronidase activity and hyaluronidase inhibitor in the serum of patients with malignant tumors.
Host-tumour relationship. XXIX. Hyaluronidase activity and seromucoid concentration in blood serum of patients with cancer.
Host-tumour relationship. XXV. Hyaluronidase activity in blood serum and ascitic fluid of rats during growth of transplanted tumours.
Host-tumour relationship. XXX. A failure to demonstrate a special hyaluronidase inhibitor in the blood serum of cancer patients.
Human breast-cancer metastasis formation in a nude-mouse model: studies of hyaluronidase, hyaluronan and hyaluronan-binding sites in metastatic cells.
HYAL-1 Hyaluronidase: A Potential Prognostic Indicator for Progression to Muscle Invasion and Recurrence in Bladder Cancer.
HYAL1 hyaluronidase in prostate cancer: a tumor promoter and suppressor.
HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion.
HYAL1 overexpression is correlated with the malignant behavior of human breast cancer.
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer.
Hyalase-Mediated Cascade Degradation of a Matrix Barrier and Immune Cell Penetration by a Photothermal Microneedle for Efficient Anticancer Therapy.
Hyaluromycin, a Novel Hyaluronidase Inhibitor, Attenuates Pancreatic Cancer Cell Migration and Proliferation.
Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.
Hyaluronan and hyaluronidase in genitourinary tumors.
Hyaluronan Degradation Promotes Cancer via Hippo-YAP Signaling: An Intervention Point for Cancer Therapy.
Hyaluronan digestion and synthesis in an experimental model of metastatic tumour.
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.
Hyaluronan in part mediates IL-1beta-induced inflammation in mouse chondrocytes by up-regulating CD44 receptors.
Hyaluronan metabolism: a major paradox in cancer biology.
Hyaluronan regulation of endothelial barrier function in cancer.
Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling.
Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves.
Hyalurondiase: both a tumor promoter and suppressor.
Hyaluronectin blocks the stimulatory effect of hyaluronan-derived fragments on endothelial cells during angiogenesis in vitro.
Hyaluronectin modulation of lung metastasis in nude mice.
Hyaluronic Acid and Hyaluronidase: Accurate Tumor Markers and Tumor Progression Regulators.
Hyaluronic acid family in bladder cancer: potential prognostic biomarkers and therapeutic targets.
Hyaluronic Acid-Coated Nanomedicine for Targeted Cancer Therapy.
Hyaluronic acid-targeted and pH-responsive drug delivery system based on metal-organic frameworks for efficient antitumor therapy.
Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death.
Hyaluronidase activity in gynaecological cancer tissues with different metastatic forms.
Hyaluronidase activity in serum of patients with monoclonal gammapathy.
Hyaluronidase additional to standard chemotherapy improves outcome for children with malignant brain tumors.
HYALURONIDASE AND CANCER.
Hyaluronidase and CD44 hyaluronan receptor expression in squamous cell laryngeal carcinoma.
Hyaluronidase and collagenase increase the transfection efficiency of gene electrotransfer in different murine tumors.
Hyaluronidase and the growth of malignant epithelial tumors.
Hyaluronidase as additive to induction chemotherapy in advanced squamous cell carcinoma of the head and neck.
Hyaluronidase binds differently DPPC, DPPS or GlcNAc-bearing glycolipid biomimetic monolayers.
Hyaluronidase can modulate expression of CD44.
Hyaluronidase Embedded in Nanocarrier PEG Shell for Enhanced Tumor Penetration and Highly Efficient Antitumor Efficacy.
Hyaluronidase enhancement of TNF-mediated cell death is reversed by TGF-beta 1.
Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo.
Hyaluronidase enhances the therapeutic effect of vinblastine in intralesional treatment of Kaposi's sarcoma. Military Medical Consortium for the Advancement of Retroviral Research (MMCARR).
Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth.
Hyaluronidase expression induces prostate tumor metastasis in an orthotopic mouse model.
Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation.
Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking.
Hyaluronidase in sera of tumour-bearing nude mice.
Hyaluronidase induces a transcapillary pressure gradient and improves the distribution and uptake of liposomal doxorubicin (Caelyx) in human osteosarcoma xenografts.
Hyaluronidase induces murine L929 fibrosarcoma cells resistant to tumor necrosis factor and Fas cytotoxicity in the presence of actinomycin D.
Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.
Hyaluronidase is more elevated in human brain metastases than in primary brain tumours.
Hyaluronidase levels in urine from Wilms' tumor patients.
Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice.
Hyaluronidase reduces human breast cancer xenografts in SCID mice.
Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner.
Hyaluronidase significantly enhances the efficacy of regional vinblastine chemotherapy of malignant melanoma.
Hyaluronidase splice variants are associated with histology and outcome in adenocarcinoma and squamous cell carcinoma of the lung.
Hyaluronidase test in serum of malignancy. II. Influence of hyaluronidase on the level of the filtrate reaction in carcinoma.
Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy.
Hyaluronidase, from wound healing to cancer (II).
Hyaluronidase, from wound healing to cancer.
Hyaluronidase-incorporated hyaluronic acid-tyramine hydrogels for the sustained release of trastuzumab.
Hyaluronidase-sensitive halos around adherent cells. Their role in blocking lymphocyte-mediated cytolysis.
Hyaluronidases and their inhibitors in the serum of colorectal carcinoma patients.
Hyaluronidases in tissue invasion.
Hyperthermal paclitaxel-bound albumin nanoparticles co-loaded with indocyanine green and hyaluronidase for treating pancreatic cancers.
Icebreaker-inspired Janus nanomotors to combat barriers in the delivery of chemotherapeutic agents.
Identification of bladder tumor-derived hyaluronidase: its similarity to HYAL1.
IgE-mediated allergic reaction to hyaluronidase in paediatric oncological patients.
In situ cross-linkable high molecular weight hyaluronan-bisphosphonate conjugate for localized delivery and cell-specific targeting: a hydrogel linked prodrug approach.
In Vivo Evaluation of a New Recombinant Hyaluronidase to Improve Gene Electro-Transfer Protocols for DNA-Based Drug Delivery against Cancer.
Increased hyaluronidase expression in more aggressive prostate adenocarcinoma.
Increased hyaluronidase levels in breast tumor metastases.
Indocyanine green encapsulated nanogels for hyaluronidase activatable and selective near infrared imaging of tumors and lymph nodes.
Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis.
Induction and reversal of cell adhesion-dependent multicellular drug resistance in solid breast tumors.
Inhibition of hyaluronan hydrolysis catalysed by hyaluronidase at high substrate concentration and low ionic strength.
Inhibition of hyaluronidase by dextran sulfate and its possible application in anticancer treatment.
International Working Group on MDS cytogenetics: October 2007 meeting report.
Interpreting the behavior of concentration-response curves of hyaluronidase inhibitors under DMSO-perturbed assay conditions.
Interstitial fluid pressure in human osteosarcoma xenografts: significance of implantation site and the response to intratumoral injection of hyaluronidase.
Intracellular NO-Generator Based on Enzyme Trigger for Localized Tumor-Cytoplasm Rapid Drug Release and Synergetic Cancer Therapy.
Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration.
Intratumoral coadministration of hyaluronidase enzyme and oncolytic adenoviruses enhances virus potency in metastatic tumor models.
Investigation of aminomethyl indole derivatives as hyaluronidase inhibitors.
Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
Involvement of hyaluronidases in colorectal cancer.
Is hyaluronan deposition in the stroma of pancreatic ductal adenocarcinoma of prognostic significance?
Isoforms of hyaluronidases can be a predictor of a prostate cancer of good prognosis.
Kinetic analysis of hyaluronidase activity using a bioactive MRI contrast agent.
LDH-stabilized ultrasmall iron oxide nanoparticles as a platform for hyaluronidase-promoted MR imaging and chemotherapy of tumors.
Light-Induced Hydrogel Based on Tumor-Targeting Mesoporous Silica Nanoparticles as a Theranostic Platform for Sustained Cancer Treatment.
Magnetic resonance imaging visualization of hyaluronidase in ovarian carcinoma.
Malignant chondroid syringoma with bone invasion: a case report and review of the literature.
Malignant mesothelioma in infancy.
Mechanism Investigation of Hyaluronidase-Combined Multistage Nanoparticles for Solid Tumor Penetration and Antitumor Effect.
Mechanistic Insights into a DMSO-Perturbing Inhibitory Assay of Hyaluronidase.
Mesoporous silica-based versatile theranostic nanoplatform constructed by layer-by-layer assembly for excellent photodynamic/chemo therapy.
Mesotheliomas and proliferative lesions of the testicular mesothelium produced in Fischer, Sprague-Dawley and Buffalo rats by methyl(acetoxymethyl)nitrosamine (DMN-OAc).
Metaphylactic effect of mitomycin C with and without hyaluronidase after transurethral resection of bladder cancer: randomized trial.
Mitochondrial targeting nanodrugs self-assembled from 9-O-octadecyl substituted berberine derivative for cancer treatment by inducing mitochondrial apoptosis pathways.
Modulation of extracellular matrix in cancer is associated with enhanced tumor cell targeting by bacteriophage vectors.
Modulation of hyaluronan catabolism in chondrocytes by mechanical stimuli.
Mucolytic enzyme systems XII. Hyaluronidase in human and animal tumors, and further studies on the serum hyaluronidase inhibitor in human cancer.
Mucolytic enzyme systems; inhibition of hyaluronidase by serum in human cancer.
Multicharge ?-cyclodextrin supramolecular assembly for ATP capture and drug release.
Multiple-Responsive Mesoporous Silica Nanoparticles for Highly Accurate Drugs Delivery to Tumor Cells.
Myxoid tumours of soft tissue: the so-called myxoid extracellular matrix is heterogeneous in composition.
Na2B12H11SH (BSH) in combination with systemic hyaluronidase: a promising concept for boron neutron capture therapy for glioblastoma.
Nanostructured Peptidotoxins as Natural Pro-Oxidants Induced Cancer Cell Death via Amplification of Oxidative Stress.
Near-infrared boosted ROS responsive siRNA delivery and cancer therapy with sequentially peeled upconversion nano-onions.
Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth.
New Horizons in the Treatment of Metastatic Pancreatic Cancer: A Review of the Key Biology Features and the Most Recent Advances to Treat Metastatic Pancreatic Cancer.
Non-immunologic enhancement and regression of self-healing squamous cell carcinoma (keratoacanthoma)--ground substance and inflammation.
Novel immunogenic antigen homologous to hyaluronidase in meningioma.
Oncolytic adenovirus with hyaluronidase activity that evades neutralizing antibodies: VCN-11.
Optimization of a Clinically Relevant Chemical-Mechanical Tissue Dissociation Workflow for Single-Cell Analysis.
Oral siRNA delivery using dual transporting systems to efficiently treat colorectal liver metastasis.
Outer-Frame-Degradable Nanovehicles Featuring Near-Infrared Dual Luminescence for in Vivo Tracking of Protein Delivery in Cancer Therapy.
Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy.
Overcoming the stromal barrier for targeted delivery of HPMA copolymers to pancreatic tumors.
Oxyhemoglobin nano-recruiter preparation and its application in biomimetic red blood cells to relieve tumor hypoxia and enhance photodynamic therapy activity.
p53 overexpression and downregulation of inter-alpha-inhibitor are associated with hyaluronidase enhancement of TNF cytotoxicity in L929 fibroblasts.
Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression.
Pd@Pt-GOx/HA as a Novel Enzymatic Cascade Nanoreactor for High-Efficiency Starving-Enhanced Chemodynamic Cancer Therapy.
Peptides that mimic glycosaminoglycans: high-affinity ligands for a hyaluronan binding domain.
Pharmacokinetics and tissue distribution of bovine testicular hyaluronidase and vinblastine in mice: an attempt to optimize the mode of adjuvant hyaluronidase administration in cancer chemotherapy.
Phenolic constituents of the Bangladeshi medicinal plant Pothos scandens and their anti-estrogenic, hyaluronidase inhibition, and histamine release inhibitory activities.
Photo-crosslinked hyaluronic acid nanoparticles with improved stability for in vivo tumor-targeted drug delivery.
Plasma hyaluronidase (Hyal-1) promotes tumor cell cycling.
Polycationic nanodrug covered with hyaluronic acid for treatment of P-glycoprotein overexpressing cancer cells.
Predicting gemcitabine delivery by 18F-FAC PET in murine models of pancreatic cancer.
Predictors of anxiety and resilience in adolescents undergoing cancer treatment.
Preparation and evaluation of tumour microenvironment response multistage nanoparticles for epirubicin delivery and deep tumour penetration.
Primary Pulmonary Myxoid Sarcoma: A Newly Described Entity-Report of a Case and Review of the Literature.
Prodrug-Based Versatile Nanomedicine with Simultaneous Physical and Physiological Tumor Penetration for Enhanced Cancer Chemo-Immunotherapy.
Production of hyaluronic acid by fibroblasts growing from explants of Walker tumor 256: production of hyaluronidase by the tumor cells.
Prolactin receptors in primary cultures of carcinogen-induced rat-mammary tumors.
Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling.
Pseudomesotheliomatous adenocarcinoma: a reappraisal.
Pseudomesotheliomatous carcinoma of the lung with histochemical and immunohistochemical study.
Rational design of a HA-AuNPs@AIED nanoassembly for activatable fluorescence detection of HAase and imaging in tumor cells.
ReCAP: Detection of Potentially Avoidable Harm in Oncology From Patient Medical Records.
Reduction/Oxidation-Responsive Hierarchical Nanoparticles with Self-Driven Degradability for Enhanced Tumor Penetration and Precise Chemotherapy.
Reflections on bladder neoplasia. Exophytic papillary urothelial tumors versus planophytic carcinoma in situ.
Regulation of hyaluronidase activity by alternative mRNA splicing.
Reversal by hyaluronidase of adhesion-dependent multicellular drug resistance in mammary carcinoma cells.
Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors.
Reversing Cancer Multidrug Resistance in Xenograft Models via Orchestrating Multiple Actions of Functional Mesoporous Silica Nanoparticles.
Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa).
Safety and Efficacy of VCN-01, an Oncolytic Adenovirus Combining Fiber HSG-Binding Domain Replacement with RGD and Hyaluronidase Expression.
Secretion of bladder tumor-derived hyaluronidase activity by invasive bladder tumor cells.
Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways.
Sensitive Hyaluronidase Biosensor Based on Target-Responsive Hydrogel Using Electronic Balance as Readout.
Sentinel node navigation surgery using indocyanine green in patients with lung cancer.
Serum inhibition of hyaluronidase following surgical procedures for cancer and nonmalignant disease.
Shell-Crosslinked Hyaluronic Acid Nanogels for Live Monitoring of Hyaluronidase Activity In Vivo.
Size-shrinkable and protein kinase C?-recognizable nanoparticles for deep tumor penetration and cellular internalization.
Smart hyaluronidase-actived theranostic micelles for dual-modal imaging guided photodynamic therapy.
Stepwise co-delivery of an enzyme and prodrug based on a multi-responsive nanoplatform for accurate tumor therapy.
Stimulation of glycosaminoglycan production in murine tumors.
Stimuli-responsive polysaccharide enveloped liposome for targeting and penetrating delivery of survivin-shRNA into breast tumor.
Strategies by which WWOX-deficient metastatic cancer cells utilize to survive via dodging, compromising, and causing damage to WWOX-positive normal microenvironment.
Stromal and epithelial expression of tumor markers hyaluronic acid and HYAL1 hyaluronidase in prostate cancer.
Subcutaneous hydration with no hyaluronidase in patients with advanced cancer.
Survivin splice variants and their diagnostic significance.
Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger.
Tachyplesin activates the classic complement pathway to kill tumor cells.
Targeted delivery of doxorubicin to tumour tissues by a novel legumain sensitive polygonal nanogel.
Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells.
Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look.
Targeting the Tumor Stroma: the Biology and Clinical Development of Pegylated Recombinant Human Hyaluronidase (PEGPH20).
The affinity of MCF7 breast cancer cells to hyaluronan substrates of different molecular weight and concentrations in an in vitro model.
The cytologic diagnosis of mesothelioma.
The effect of collagenase and hyaluronidase on transient perfusion in human osteosarcoma xenografts grown orthotopically and in dorsal skinfold chambers.
The effect of serum hyaluronidase on acidic polysaccharides and its activity in cancer.
The effects of hyalurodinase upon tumor formation in BALB/c mice painted with 7,12-dimethylbenz-(a)anthracene.
The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44.
The growth rate of two transplantable murine tumors, 3LL lung carcinoma and B16F10 melanoma, is influenced by Hyal-1, a locus determining hyaluronidase levels and polymorphism.
The human mixed lymphocyte-tumor cell interaction test. I. Positive autologous lymphocyte proliferative responses can be stimulated by tumor cells as well as by cells from normal tissues.
The hyaluronidase content of necrotic tumor and testis tissue.
The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus.
The impact of enzymatic degradation on the uptake of differently sized therapeutic molecules.
The impact of extracellular matrix on the chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy.
The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma.
The pattern of metastasis of human melanoma to the central nervous system is not influenced by integrin alpha(v)beta(3) expression.
The relationship between hyaluronidase activity and hyaluronic acid concentration in sera from normal controls and from patients with disseminated neoplasm.
Theranostic nanoparticles with tumor-specific enzyme-triggered size reduction and drug release to perform photothermal therapy for breast cancer treatment.
Theranostic size-reducible and no donor conjugated gold nanocluster fabricated hyaluronic acid nanoparticle with optimal size for combinational treatment of breast cancer and lung metastasis.
Therapeutic potential of russelioside B as anti-arthritic agent in Freund's adjuvant-induced arthritis in rats.
Transforming growth factor-beta protection of cancer cells against tumor necrosis factor cytotoxicity is counteracted by hyaluronidase (review).
Transforming growth factor-beta1 blocks the enhancement of tumor necrosis factor cytotoxicity by hyaluronidase Hyal-2 in L929 fibroblasts.
Treatment of adenocarcinoma of the liver with mitomycin, hyaluronidase, and ethanol: an experimental study in the rat.
Tumor cell-activated "Sustainable ROS Generator" with homogeneous intratumoral distribution property for improved anti-tumor therapy.
Tumor cell-induced deactivation of human monocytes.
Tumor cell-on fluorescence imaging agent using hyaluronate dots.
Tumor environment differentiated "nanodepot" programmed for site-specific drug shuttling and combinative therapy on metastatic cancer.
Tumor microenvironment targeting with dual stimuli-responsive nanoparticles based on small heat shock proteins for antitumor drug delivery.
Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots.
Tumor-associated hyaluronan limits efficacy of monoclonal antibody therapy.
Tumor-derived hyaluronidase: a diagnostic urine marker for high-grade bladder cancer.
Tumor-specific nanomedicine via sequential catalytic reactions for accurate tumor therapy.
Tumor-Targeted Graphitic Carbon Nitride Nanoassembly for Activatable Two-Photon Fluorescence Imaging.
Turn-on theranostic fluorescent nanoprobe by electrostatic self-assembly of carbon dots with doxorubicin for targeted cancer cell imaging, in vivo hyaluronidase analysis, and targeted drug delivery.
Two Case Reports of Intravenous Leiomyomatosis with Hyaluronan Expression.
Update on phase I studies in advanced pancreatic adenocarcinoma. Hunting in darkness?
Upregulation of HYAL1 Expression in Breast Cancer Promoted Tumor Cell Proliferation, Migration, Invasion and Angiogenesis.
Urinary hyaluronic acid and hyaluronidase: markers for bladder cancer detection and evaluation of grade.
Viral Capsids Mimicking Based on pH-Sensitive Biodegradable Polymeric Micelles for Efficient Anticancer Drug Delivery.
WWOX Possesses N-Terminal Cell Surface-Exposed Epitopes WWOX7-21 and WWOX7-11 for Signaling Cancer Growth Suppression and Prevention In Vivo.
[A case of malignant mesothelioma of the pleura and the peritoneum detected by sudden onset of back pain and pleural effusion and ascites]
[ASCO- and ESMO-update 2017 - highlights of the 53. meeting of the American Society of Clinical Oncology/ASCO 2017 and European Society for Medical Oncology/ESMO congress 2017].
[Cisplatin, vindesine and hyaluronidase combined with simultaneous radiotherapy of advanced head and neck tumors]
[Combination chemotherapy of solid tumor--effects of hyaluronidase on doxorubicin (DXR) penetration into multicellular tumor spheroids (MTS)]
[Effects of adjuvant hyaluronidase in tumors refractory to chemotherapy. Review of the literature and pharmacokinetics of cisplatin after regional administration in animals and humans]
[Examination of hyaluronidase inhibition in the serum of cancer patients.]
[Histochemical studies of bladder tumors]
[Hyaluronic acid and hyaluronidase. 2 new bladder carcinoma markers]
[Hyaluronic acid. Usefulness and perspectives of its serum assay]
[Hyaluronidase activity in the blood serum of women with benign and malignant tumors of the ovaries]
[Hyaluronidase and tumors: antihyaluronidase mesomucinase power of human blood in neoplasms before and after roentgentherapy.]
[Hyaluronidase and tumors; antihyaluronidase (mesomucinase) power of the blood before and after roentgenotherapy of neoplasms.]
[Hyaluronidase as a factor in tumor metastasis.]
[Hyaluronidase in cytostatic therapy of ENT tumors]
[Hyaluronidase serum test in cancer. I. Hyaluronidase test in diagnosis.]
[On hyaluronidase activity of the blood in leukosis, lymphogranulomatosis and cancer.]
[Primary malignant tumor of the liver with extraordinary increase of mucopolysaccharides in the blood forming a visible reticulum in smears of total blood, blood serum, and hemopoietic organs, effect of hyaluronidase.]
[Production of hyaluronidase by cultured human tumor cells]
[Significance of hyaluronidase for tumor growth.]
[Some probable therapeutic effects of the treatment of malignant neoplasms with a combination of lecithinase A, gamma globulin and hyaluronidase.]
[Studies on hyaluronidase in malignant tumour.]
[The effect of hyperthermia on tumors. Experimental animal studies on the influence of healthy environment in tumor therapy with short wave hyperthermia, tested by injection of the area surrounding the carcinoma with hyaluronidase.]
Neoplasms, Squamous Cell
Combined application of cisplatin, vindesine, hyaluronidase and radiation for treatment of advanced squamous cell carcinoma of the head and neck.
Nephritis
Antibody response to bacteriophage hyaluronidase in acute glomerulonephritis after group A streptococcal infection.
[Hyaluronidase activity of the blood serum in nephritis and its change under the influence of hormone therapy.]
Nephrolithiasis
[Medical therapy of nephrolithiasis by increasing the protective urinary colloids with hyaluronidase.]
[Value of hyaluronidase in local treatment of nephrolithiasis.]
Nephrosis
Lipemia clearing by hyaluronidase, hyaluronate, and desoxycorticosterone, and its inhibition by cortisone, stress, and nephrosis.
Mucolytic enzyme systems. XI. Hyaluronidase inhibitor and serum mucoproteins in patients with lipoid nephrosis and acute glomerulonephritis.
[Hyaluronidase activity of urine in necrotic nephrosis.]
Nephrosis, Lipoid
Mucolytic enzyme systems. XI. Hyaluronidase inhibitor and serum mucoproteins in patients with lipoid nephrosis and acute glomerulonephritis.
Nephrotic Syndrome
Glucocorticoids enhance interleukin-4 production to neo-antigen (hyaluronidase) in children immunocompromised with cytostatic drugs.
[Anti-edema effect of hyaluronidase in nephrotic syndrome; preventive note.]
Obesity
Differences in the mechanism of type 1 and type 2 diabetes-induced skin dryness by using model mice.
Obstetric Labor, Premature
Bacterial Hyaluronidase Promotes Ascending GBS Infection and Preterm Birth.
Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates.
[Use of hyaluronidase in premature labor]
Ocular Hypertension
[Considerations on medical treatment with hyaluronidase in ocular hypertension caused by cortisone]
Oligodendroglioma
Effect of hyaluronidase treatment of intact cells on hyaluronate synthetase activity.
Onychomycosis
[Treatment of onychomycosis by ablation of nails with hyaluronidase.]
Ophthalmoplegia
A Case of Hyaluronic Acid Induced Blindness With Ophthalmoplegia and Ptosis.
Hyaluronidase in the treatment of exophthalmic ophthalmoplegia.
Optic Nerve Diseases
Compressive optic neuropathy secondary to an allergic reaction to hyaluronidase.
Optic Nerve Glioma
Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth.
Optic Neuropathy, Ischemic
Efficacy of Retrobulbar Hyaluronidase Injection for Vision Loss Resulting from Hyaluronic Acid Filler Embolization.
Oral Submucous Fibrosis
A randomized double-blind, multiple-arm trial comparing the efficacy of submucosal injections of hyaluronidase, dexamethasone, and combination of dexamethasone and hyaluronidase in the management of oral submucous fibrosis.
Efficacy of alpha lipoic acid in adjunct with intralesional steroids and hyaluronidase in the management of oral submucous fibrosis.
Efficacy of betamethasone, hyaluronidase and its combination on mouth opening, burning sensation and QOL in patients with OSF.
Efficacy of hyaluronidase combined with corticosteroids in treatment of oral submucous fibrosis: a meta-analysis of randomised controlled clinical trials.
Efficacy of oral colchicine with intralesional hyaluronidase or triamcinolone acetonide in the Grade II oral submucous fibrosis.
In vivo autofluorescence characteristics of pre- and post-treated oral submucous fibrosis: a pilot study.
Management of Oral Submucous Fibrosis with Injection of Hyaluronidase and Dexamethasone in Grade III Oral Submucous Fibrosis: A Retrospective Study.
Management of oral submucous fibrosis: a conservative approach.
Oral submucous fibrosis--a new treatment regimen.
Oral submucous fibrosis--treatment with hyalase.
Vasodilator isoxsuprine alleviates symptoms of oral submucous fibrosis.
Orbital Cellulitis
Hyaluronidase allergy mimicking orbital cellulitis.
Hyaluronidase hypersensitivity: A rare complication of peribulbar block.
Orbital cellulitis as a postoperative complication of sub-Tenon anaesthesia in cataract surgery.
Orbital cellulitis vs allergic reaction to hyaluronidase as the cause of periorbital oedema.
Orbital Pseudotumor
Hyaluronidase induced orbital pseudotumor as complication of retrobulbar anesthesia.
Orchitis
Hyaluronidase and experimental syphilis. III. Metachromasia in syphilitic orchitis and its relationship to hyaluronic acid.
Osteoarthritis
A synthetic polymeric biolubricant imparts chondroprotection in a rat meniscal tear model.
Examination of synovial fluid and serum hyaluronidase activity as a joint marker in rheumatoid arthritis and osteoarthritis patients (by zymography).
Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time reverse transcriptase polymerase chain reaction.
Gene expression and activity of cartilage-degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts.
Hyaluronidase and its substrate hyaluronan: biochemistry, biological activities and therapeutic uses.
Inhibition of hyaluronidase activity by select sorghum brans.
Investigation of aminomethyl indole derivatives as hyaluronidase inhibitors.
The pericellular hyaluronan of articular chondrocytes.
Osteosarcoma
Endo- and exoglycosidases in an experimental rat osteosarcoma.
Hyaluronidase induces a transcapillary pressure gradient and improves the distribution and uptake of liposomal doxorubicin (Caelyx) in human osteosarcoma xenografts.
Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner.
Interstitial fluid pressure in human osteosarcoma xenografts: significance of implantation site and the response to intratumoral injection of hyaluronidase.
Overexpression of KIAA1199, a novel strong hyaluronidase, is a poor prognostic factor in patients with osteosarcoma.
The effect of collagenase and hyaluronidase on transient perfusion in human osteosarcoma xenografts grown orthotopically and in dorsal skinfold chambers.
Otitis
[Hyaluronidase activity of the blood serum and spinal fluid in chronic suppurative otitis and otogenic intracranial complications]
[Local antibiotics with hyaluronidase in therapy of chronic otitis.]
[The role of hyaluronidase in the occurrence of a generalized pneumococcal infection]
Otitis Media
A study of pathogenic factors of Streptococcus pneumoniae strains causing meningitis.
Ovarian Neoplasms
Hyaluronidase activity in gynaecological cancer tissues with different metastatic forms.
Pancreatic Fistula
HYAL-1-induced autophagy facilitates pancreatic fistula for patients who underwent pancreaticoduodenectomy.
Pancreatic Neoplasms
Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology.
Current treatment landscape and emerging therapies for pancreatic cancer.
Effect of Matrix-Modulating Enzymes on The Cellular Uptake of Magnetic Nanoparticles and on Magnetic Hyperthermia Treatment of Pancreatic Cancer Models In Vivo.
HALO-109-301: a Phase III trial of PEGPH20 (with gemcitabine and nab-paclitaxel) in hyaluronic acid-high stage IV pancreatic cancer.
Hyaluromycin, a Novel Hyaluronidase Inhibitor, Attenuates Pancreatic Cancer Cell Migration and Proliferation.
Hyperthermal paclitaxel-bound albumin nanoparticles co-loaded with indocyanine green and hyaluronidase for treating pancreatic cancers.
Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.
[ASCO- and ESMO-update 2017 - highlights of the 53. meeting of the American Society of Clinical Oncology/ASCO 2017 and European Society for Medical Oncology/ESMO congress 2017].
Pancreatitis, Graft
Hyaluronidase treatment of graft pancreatitis in rats: marked effects on the blood perfusion of the transplanted pancreas.
Papilloma
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
Histochemical AMD electron microscopic studies of intercellular matrices of papilloma induced by painting DMBA on the skin of mice.
Paraphimosis
Hyaluronidase as an aid to correction of paraphimosis: report of a case.
Hyaluronidase in Paraphimosis.
Hyaluronidase in the treatment of paraphimosis.
Hyaluronidase in treatment of sequela of paraphimosis.
Reduction of paraphimosis with hyaluronidase.
[Hyaluronidase in treatment of paraphimosis.]
[New treatment of paraphimosis with local subcutaneous hyaluronidase injections.]
[Paraphimosis treated with hyaluronidase.]
Paraproteinemias
Effect of anticoagulants on the plasma hyaluronidase activities.
Hyaluronidase activity in serum of patients with monoclonal gammapathy.
Paresis
New Treatment Approaches on the Horizon for Spastic Hemiparesis.
Pemphigus
Production of bullae in pemphigus with hyaluronidase.
[Correlation between hyaluronidase and hyaluronic acid in pemphigus and Duhring's disease.]
Penile Induration
The use of betamethasone and hyaluronidase injections in the treatment of Peyronie's disease.
Periarthritis
[Administration of hyaluronidase in paratenonitis crepitans and tendinoses (epicondylitis humeri and periarthritis humero-scapularis)]
Periodontal Diseases
Elaboration of hyaluronidase and chondroitin sulfatase by microorganisms inhabiting the gingival sulcus: evaluation of a screening method for periodontal disease.
Hyaluronan (hyaluronic acid) and its regulation in human saliva by hyaluronidase and its inhibitors.
Hyaluronidase in periodontal disease.
[Activity of hyaluronidase, tissue and streptococcus antihyaluronidase in the blood serum of patients with inflammatory dystrophic form of periodontal disease]
[Changes in the hyaluronidase and antihyaluronidase activity in the treatment of inflammatory-dystrophic forms of periodontal disease]
[Effect of testicular lidase and streptococcal hyaluronidase on bone resorption of the alveolar process in experimental periodontal diseases]
Periodontal Pocket
Phase variation of hyaluronidase-producing peptostreptococci associated with periodontal disease.
Periodontitis
Anti-streptococcal hyaluronidase and periodontitis.
Influence of anticholinergic drugs on the development of an experimental periodontitis model.
Peripheral Arterial Disease
Intra-arterial hyaluronidase in severe peripheral arterial disease.
Peripheral Vascular Diseases
Treatment of edema caused by chronic phlebothrombosis and other peripheral vascular diseases with hyaluronidase.
Pharyngitis
Extracellular factors, blood group antigens, and bacteriophage of nephritogenic and nonnephritogenic strains of M-type 12 streptococci.
Phimosis
Structural analysis of the phimotic prepuce in patients with failed topical treatment compared with untreated phimosis.
Topical betamethasone and hyaluronidase in the treatment of phimosis in boys: a double-blind, randomized, placebocontrolled trial.
Topical corticosteroids for phimosis in children: a network meta-analysis of randomized clinical trials.
Ultrastructural Analysis of the Foreskin in Patients with True Phimosis Treated or Not- Treated with Topic Betamethasone and Hyaluronidase Ointment.
Pituitary Neoplasms
Melatonin inhibits growth of diethylstilbestrol-induced prolactin-secreting pituitary tumor in vitro: possible involvement of nuclear RZR/ROR receptors.
Placenta, Retained
Bovine retained placenta: effects of collagenase and hyaluronidase on detachment of placenta.
Pleural Effusion
[Clinical use and experiences with hyaluronidase in pleural effusions.]
Pneumococcal Infections
[The role of hyaluronidase in the occurrence of a generalized pneumococcal infection]
Pneumonia
Antihyaluronidase antagonistic to pneumococcus hyaluronidase in the serum of normal human beings and patients with pneumococcic pneumonia; rise of titer in bacteremic pneumococcic pneumonia.
Elaboration of hyaluronidase by pneumococci isolated from bacteremic pneumococcic pneumonia patients.
[Hydroxyproline excretion and serum hyaluronidase activity in older children with chronic non-specific pneumonia]
[Treatment of subchronic pneumonia with hyaluronidase aerosol; preliminary report.]
[Use of hyaluronidase in chronic pneumonia]
Pneumothorax
[Hyaluronidase therapy of pleural empyema with open spontaneous pneumothorax.]
Poliomyelitis
A comparative study on muscular involvement in experimental poliomyelitis induced by various strains of virus, and the effect of hyaluronidase on the intramuscular inoculation.
Hyaluronidase and renal calculi in poliomyelitis.
Mucolytic enzyme systems; inhibition of hyaluronidase oy serum in poliomyelitis.
Relationship of physiological inhibitor of hyaluronidase to experimental poliomyelitis.
[ATTEMPTED USE OF HYALURONIDASE IN THE REHABILITATION OF PATIENTS WITH KNEE CONTRACTURES FOLLOWING ACUTE ANTERIOR POLIOMYELITIS.]
Polyhydramnios
[ON THE HYALURONIDASE ACTIVITY OF THE AMNIOTIC FLUID IN NORMAL PREGNANCY AND IN HYDRAMNIOS.]
Pregnancy, Prolonged
[ACTIVITY OF HYALURONIDASE IN THE BLOOD OF WOMEN IN TERM AND PROLONGED PREGNANCY AND ITS CHANGES UNDER THE INFLUENCE OF VITAMINS C AND P.]
[Artificial dilatation of the cervix uteri with dexamethasone and hyaluronidase. I. Application during labor in women with prolonged pregnancy]
Premature Birth
Bacterial Hyaluronidase Promotes Ascending GBS Infection and Preterm Birth.
Pressure Ulcer
Hyaluronan in human acute and chronic dermal wounds.
Priapism
[Priapism, trial therapy with liquemin and hyaluronidase.]
Primary Immunodeficiency Diseases
Evaluating dose ratio of subcutaneous to intravenous immunoglobulin therapy among patients with primary immunodeficiency disease switching to 20% subcutaneous immunoglobulin therapy.
Human immunoglobulin 10 % with recombinant human hyaluronidase: replacement therapy in patients with primary immunodeficiency disorders.
Long-Term Tolerability, Safety, and Efficacy of Recombinant Human Hyaluronidase-Facilitated Subcutaneous Infusion of Human Immunoglobulin for Primary Immunodeficiency.
Practical Considerations for Self-Administration of Subcutaneous Immunoglobulin G Utilizing Recombinant Human Hyaluronidase, an Advanced Method of Subcutaneous Administration: A Nurse's Perspective.
Prostatic Neoplasms
Association of elevated levels of hyaluronidase, a matrix-degrading enzyme, with prostate cancer progression.
Comparison of the prognostic potential of hyaluronic acid, hyaluronidase (HYAL-1), CD44v6 and microvessel density for prostate cancer.
Epigenetic Regulation of HYAL-1 Hyaluronidase Expression: IDENTIFICATION OF HYAL-1 PROMOTER.
Evaluation of the prognostic potential of hyaluronic acid and hyaluronidase (HYAL1) for prostate cancer.
Fluorescence lifetime imaging with time-gated detection of hyaluronidase using a long lifetime azadioxatriangulenium (ADOTA) fluorophore.
FRET based Ratio-metric Sensing of Hyaluronidase in Synthetic Urine as a Biomarker for Bladder and Prostate Cancer.
HYAL1 hyaluronidase in prostate cancer: a tumor promoter and suppressor.
Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels.
Hyaluronic acid and hyaluronidase as possible novel urine biomarkers for the diagnosis of prostate cancer.
Hyaluronic acid and hyaluronidase: molecular markers associated with prostate cancer biology and detection.
Hyaluronidase enhancement of TNF-mediated cell death is reversed by TGF-beta 1.
Hyaluronidase expression induces prostate tumor metastasis in an orthotopic mouse model.
Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer.
Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis.
Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling.
Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing.
Stromal and epithelial expression of tumor markers hyaluronic acid and HYAL1 hyaluronidase in prostate cancer.
Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells.
Prostatitis
[New opportunities of using gialuronidase in chronic prostatitis].
Proteinuria
Endothelial surface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice.
Roles of glomerular endothelial hyaluronan in the development of proteinuria.
Pseudoxanthoma Elasticum
Effect of selective enzymatic digestions on skin biopsies from pseudoxanthoma elasticum: an ultrastructural study.
Psoriasis
[Changes in the acid and alkaline phosphatase and acid hyaluronidase activities in skin homogenates in psoriasis]
[Hyaluronic acid. Usefulness and perspectives of its serum assay]
Pterygium
Hyaluronidase therapy in pterygium.
Role of Hyaluronidase (Hyalase) in management of pterygium.
Sudden amblyopia following hyaluronidase (hyalase) in a case of early pterygium. A case report.
Pulmonary Disease, Chronic Obstructive
Functional residual capacity and airway resistance in rats of COPD model induced by systemic hyaluronidase.
Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology.
[Metabolism of the main substance of the connective tissue in chronic obstructive pulmonary disease]
Pulmonary Edema
[Effects of hyaluronidase on experimental adrenalin-induced acute pulmonary edema.]
Pulmonary Fibrosis
Antifibrotic effect of combined treatment with neuroleptic drug and immobilized hyaluronidase in pulmonary fibrosis.
Effect of immobilized hyaluronidase on stem and progenitor cells in pulmonary fibrosis.
HYALURONIDASE-LOADED PLGA MICROPARTICLES AS A NEW STRATEGY FOR THE TREATMENT OF PULMONARY FIBROSIS.
Micellar Hyaluronidase and Spiperone as a Potential Treatment for Pulmonary Fibrosis.
Pulpitis
Comparative Evaluation of the Efficacy of 2% Lidocaine Containing 1:200,000 Epinephrine with and without Hyaluronidase (75 IU) in Patients with Irreversible Pulpitis.
Pyelonephritis
[Protein fractions and hyaluronidase activity in the blood serum in pyelonephritis (experimental study)]
[Protein fractions and the activity of hyaluronidase in the blood serum in pyelonephritis (experimental study)]
Pyloric Stenosis
[Hyaluronidase and pyloric stenosis.]
Rabies
[Effect of hyaluronidase on the evolution of street-virus rabies in mice.]
[Effects of hyaluronidase on experimental rabies infection in mice.]
Radiculopathy
An evaluation of the effectiveness of hyaluronidase in the selective nerve root block of radiculopathy: a double blind, controlled clinical trial.
Comment on the Evaluation of the Effectiveness of Hyaluronidase in the Selective Nerve Root Block of Radiculopathy.
Percutaneous epidural neuroplasty: prospective evaluation of 0.9% NaCl versus 10% NaCl with or without hyaluronidase.
Rectal Prolapse
Hyaluronidase in the reduction of incarcerated rectal prolapse: a novel use.
Refractive Errors
Hyaluronidase treatment, collagen fibril packing, and normal transparency in rabbit corneas.
Renal Insufficiency
Can Plasma Hyaluronan and Hyaluronidase Be Used As Markers of the Endothelial Glycocalyx State in Patients with Kidney Disease?
Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
Reperfusion Injury
Effects of hyaluronidase on reducing myocardial infarct size in a baboon model of ischemia-reperfusion injury.
Retinal Artery Occlusion
Assessing Retrobulbar Hyaluronidase as a Treatment for Filler-Induced Blindness in a Cadaver Model.
Can We Restore Vision? A Cadaveric Study Using Hyaluronidase for Retinal Artery Occlusion.
Efficacy of Retrobulbar Hyaluronidase Injection for Vision Loss Resulting from Hyaluronic Acid Filler Embolization.
Superselective Arterial Hyaluronidase Thrombolysis Is Not an Effective Treatment for Hyaluronic Acid-Induced Retinal Artery Occlusion: Study in a Rabbit Model.
Retinal Detachment
Decreased hyaluronan concentration during primary rhegmatogenous retinal detachment.
Experimental retinal detachment in owl monkeys. Effect of intravitreal hyaluronidase injection and embolization of the choroidal and retinal circulation.
Investigations into hyaluronic acid and hyaluronidase in the subretinal fluid in retinal detachment, partly due to ruptures and partly secondary to malignant choroidal melanoma; preliminary report suggesting a new hypothesis concerning the pathogenesis of retinal detachment.
Lysosomal hyaluronidase in the subretinal fluid of patients with rhegmatogenous retinal detachments.
Retinal Vein Occlusion
Retinal vasculopathy in Fanconi anemia.
Retinoblastoma
Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site.
Retinopathy of Prematurity
Level of hyaluronidase inhibitor in the serum of premature infants with retrolental fibroplasia.
Rheumatic Diseases
Hyaluronidase activity in the skin, rheumatic disease, and salicylates.
Hyaluronidase inhibitory substances in sera from patients with rheumatic disease.
[Activity of hyaluronidase (spread-factor) in blood serum in rheumatism.]
[CLINICAL OBSERVATIONS ON THE THERAPEUTIC USE OF INTRA-ARTICULAR HYALURONIDASE IN CHRONIC RHEUMATIC DISEASES.]
[Clinico-experimental research on mechanism of action of heparin in rheumatic diseases; heparin tolerance of the rheumatic subject; interaction of hyaluronidase on blood coagulation factors in vitro; relations between hyaluronidase, heparin and salicylates in regard to intradermal diffusion of staining substances.]
[Corticosteroids and hyaluronidase in the etiology of rheumatism.]
[Dynamics of the titers of antifibrinolysin, antistreptolysin-O, hyaluronidase activity and allergic reaction of the skin in patients with rheumatism]
[Hyaluronidase activity and diphenyl and cup tests in patients with rheumatism.]
[HYALURONIDASE ACTIVITY IN THE COURSE OF RHEUMATISM UNDER THE INFLUENCE OF HORMONO-DRUG THERAPY.]
[Hyaluronidase and rheumatism.]
[Rheumatism and hyaluronidase.]
[The critique of hyaluronidase theories in rheumatic diseases.]
[Therapy of rheumatic diseases of the joints with hyaluronidase inhibitors.]
Rheumatic Fever
Effect of adrenocorticotrophic hormone (ACTH) on serum hyaluronidase inhibitor in rheumatic fever.
Hyaluronidase Inhibition by Sodium Salicylate in Rheumatic Fever.
Hyaluronidase inhibition by sodium salicylate in rheumatic fever.
Hyaluronidase spread and the effect of salicylates in rheumatic fever.
Immunologic and biochemical studies in infants and children with special reference to rheumatic fever; inhibition of hyaluronidase by sera.
Mucolytic enzyme systems; nonspecific hyaluronidase inhibitor in rheumatic fever.
Nonspecific hyaluronidase inhibitor concentrations in the blood serum of siblings and parents of children with rheumatic fever.
Relations of hyaluronidase to salicylates and rheumatic fever.
[A method for determination of antistreptococcal hyaluronidase; levels in normal subjects and in rheumatic fever; preliminary report.]
[Clinical study on synthetic hyaluronidase inhibitors in rheumatic arthritis.]
Rheumatic Heart Disease
[ACTH therapy of rheumatic heart disease and modification of blood hormone proteins, and hyaluronidase during therapy.]
[Examination of hyaluronidase and histamine in blood in rheumatic heart disease.]
Rhinitis, Allergic
Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis.
Rhinitis, Atrophic
[Pasteurelloses]
Rickets
Localization of sudanophil material at the sites of calcification in dentine, and the compact bone and epiphyseal cartilage plate of tibia in the rat given beryllium carbonate.
Salpingitis
[Use of hyaluronidase in chronic salpingitis.]
Sarcoma
Establishment and characterization of a cell line from a malignant fibrous histiocytoma of bone developing in a patient with multiple fibrous dysplasia.
Sarcoma 180
Physiological activities of a beta-glucan produced by Panebacillus polymyxa.
Sarcoma 37
Effect of purified hyaluronidase on growth of sarcoma 37 in the mouse.
Sarcoma, Avian
The splicing pattern of fibronectin mRNA changes during chondrogenesis resulting in an unusual form of the mRNA in cartilage.
Sarcoma, Experimental
[The influence of hyaluronidase and 2, 4, 6-triethylenimino-1, 3, 5-triazine (TEM) on the growth of the Jensen sarcoma of the rat.]
Sarcoma, Kaposi
Hyaluronidase enhances the therapeutic effect of vinblastine in intralesional treatment of Kaposi's sarcoma. Military Medical Consortium for the Advancement of Retroviral Research (MMCARR).
Sarcoma, Synovial
Histochemical characterization of mucosubstances in synovial sarcoma.
Scarlet Fever
[Antistreptococcal hyaluronidase titers and serum protein patterns during scarlet fever.]
Schistosomiasis
Detection of bladder carcinoma by combined testing of urine for hyaluronidase and cytokeratin 20 RNAs.
Expression of HYAL1 and survivin RNA as diagnostic molecular markers for bladder cancer.
Sciatica
The additional effect of hyaluronidase in lumbar interlaminar epidural injection.
Scleredema Adultorum
[Experience with ACTH and hyaluronidase treatment of a case of scleredema adultorum Buschke, Mayr type.]
Scleroderma, Diffuse
[Hyaluronidase therapy of progressive scleroderma]
[Our experience in the treatment of progressive scleroderma with hyaluronidase]
Scleroderma, Systemic
[Treatment of systemic scleroderma with high dosage of intravenous hyaluronidase]
Scoliosis
Collagen, proteoglycan and hyaluronidase activity in cultures from normal and scoliotic chicken fibroblasts.
Scurvy
Biological function of ascorbic acid and the pathogenesis of scurvy: a working hypothesis.
Seizures
Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix in vivo Can Induce Seizures in Neonatal Mice.
Sepsis
Evidence that the serum inhibitor of hyaluronidase may be a member of the inter-alpha-inhibitor family.
Glycocalyx in Endotoxemia and Sepsis.
Hydroxyethyl starch in severe sepsis: end of starch era?
Immunomodulatory activity of hyaluronidase is associated with metabolic adaptations during acute inflammation.
Inhibitors of the hyaluronidases.
The glycocalyx: a novel diagnostic and therapeutic target in sepsis.
[Fatal sepsis after hyaluronidase injection with an infiltrate syringe.]
[Hyaluronidase and staphylococcal septicemia.]
Shock, Septic
Streptococcal pyrogenic exotoxin A, streptolysin O, exoenzymes, serotype and biotype profiles of Streptococcus pyogenes isolates from patients with toxic shock syndrome and other severe infections.
Silicosis
[Action of dextran-modified hyaluronidase in experimental silicosis]
[Effect of hyaluronidase on experimental silicosis in rats.]
[Experiments on the problem of the effect of the inhalation of hyaluronidase during exposure to dust on the development of silicosis in rats.]
[Treatment of silicosis with hyaluronidase; first clinicoradiological results.]
Skin Diseases
Assay of hyaluronidase in various dermatoses.
Inhibition of hyaluronidase by serum in skin diseases.
Injected Hyaluronidase Reduces the Volume of Exogenous Hyaluronate Fillers in Mice and Results in Clinical Improvement in a Patient with Pretibial Myxedema.
Mucolytic enzyme systems; inhibition of hyaluronidase by serum in skin diseases.
Studies on mucopolysaccharide in skin diseases. I. Treatment of urticaria pigmentosa with hyaluronidase.
[Hyaluronidase test--an indicator of the condition of pathologic skin process in the health resort therapy of dermatoses]
[Studies on hyaluronidase inhibitor in serum of skin diseases.]
Skin Ulcer
The use of hyaluronidase in the treatment of chronic skin ulcers in diffuse generalized scleroderma.
Soft Tissue Injuries
Use of hyaluronidase in soft tissue injury and its influence on experimental bone repair.
Spasm
Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase.
Spinal Cord Injuries
Effect of hyaluronidase on acute spinal cord injury.
Spinal Stenosis
Hyaluronidase in Neuroplasty: A Review.
Spondylarthropathies
[Criteria for the differential diagnosis of spondyloarthropathies, by determining serum hyaluronidase activity]
Squamous Cell Carcinoma of Head and Neck
Expression of tumor markers hyaluronic acid and hyaluronidase (HYAL1) in head and neck tumors.
Starvation
Influence of post-starvation extraction time and prey-specific diet in Tityus serrulatus scorpion venom composition and hyaluronidase activity.
Stomach Neoplasms
[HYALURONIDASE ACTIVITY OF THE BLOOD SERUM OF PATIENTS WITH GASTRIC CANCER AND ULCER DURING THE PRE- AND POSTOPERATIVE PERIODS.]
[Inhibitory effect of hyaluronic acid, hyaluronidase and RGD on adhesion and invasion of human gastric cancer cell line SGC7901]
Stomach Ulcer
[Hyaluronidase in experimental gastric ulcer of the rat.]
Strabismus
A comparison of mepivacaine versus lidocaine for episcleral (sub-tenon's) block for cataract surgery in an ambulatory setting.
Associated phoria and the measuring and correcting methodology after H.-J. Haase (MKH).
Recovery of extraocular muscle function after adjustable suture strabismus surgery under local anesthesia.
Repeatability of Associated Phoria Tests.
Second cluster of strabismus cases after periocular anesthesia without hyaluronidase.
Symposium Proceedings Abstracts of papers presented at the Symposium (to honor Prof. Dr. Wolfgang Haase on his 60th birthday) on Visual Development and 'Update' in Strabismus.
[Do prism corrections according to H.-J. Haase affect ocular prevalence?]
Streptococcal Infections
Antibody response to bacteriophage hyaluronidase in acute glomerulonephritis after group A streptococcal infection.
Comparative genomics reveals close genetic relationships between phages from dairy bacteria and pathogenic Streptococci: evolutionary implications for prophage-host interactions.
Enzyme-linked immunosorbent assay for identification and measurement of antibodies to group A streptococcal bacteriophage.
Studies on streptococcal hyaluronidase and antihyaluronidase. III. The production and cellular localization of hyaluronidase following streptococcal infection.
The role of hyaluronidase in experimental streptococcal infection.
The role of hyaluronidase in hemolytic streptococcal infection.
THE ROLE OF THE MUCOID POLYSACCHARIDE (HYALURONIC ACID) IN THE VIRULENCE OF GROUP A HEMOLYTIC STREPTOCOCCI.
[Data on a study of the biological properties of streptococcal hyaluronidase. II. On the effect of streptococcal hyaluronidase on the course of experimental streptococcal infection.]
Stroke
Effect of hyaluronidase on experimental cerebral infarct size and mortality.
Hyaluronidase inhibition accelerates functional recovery from stroke in the mouse brain.
Subarachnoid Hemorrhage
Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase.
Superinfection
[Effect of hyaluronidase on experimental tuberculous superinfection.]
Suppuration
[Pulmonary suppuration and hyaluronidase.]
Swine Erysipelas
[Infectious process in swine erysipelas in hyaluronidase; preliminary communication.]
Synovial Cyst
Hyaluronidase therapy of synovial cysts.
Syphilis
Hyaluronidase and experimental syphilis. III. Metachromasia in syphilitic orchitis and its relationship to hyaluronic acid.
Hyaluronidase and experimental syphilis; the attempted localization of lesions in syphilitic rabbits by intradermal and by intracorneal injections of hyaluronidase; a negative report.
Hyaluronidase and experimental syphilis; the length of incubation periods in experimental primary syphilis with and without hyaluronidase.
[Hyaluronidase activity as a factor of vascular permeability in patients with syphilis during treatment]
[Influence of hyaluronidase on the course of experimental syphilis in the rabbit.]
Tendinopathy
In-Vivo Efficacy of Recombinant Human Hyaluronidase (rHuPH20) Injection for Accelerated Healing of Murine Retrocalcaneal Bursitis and Tendinopathy.
[Administration of hyaluronidase in paratenonitis crepitans and tendinoses (epicondylitis humeri and periarthritis humero-scapularis)]
Tenosynovitis
[Use of hyaluronidase in acute tenosynovitis crepitans]
Teratozoospermia
Semen assessment, fertility and the selection of Hereford bulls for use in AI.
Tetanus
[Favorable effect of serotherapy of tetanus with hyaluronidase.]
Thromboembolism
Delayed skin necrosis following hyaluronic acid filler injection: A case report.
Thrombophlebitis
[CONTRIBUTION TO THE TREATMENT OF SUPERFICIAL THROMBOPHLEBITIS IN PREGNANCY AND PUERPERIUM WITH A HEPARINOID AND HYALURONIDASE OINTMENT.]
[HEPARINOID AND HYALURONIDASE COMBINATION IN THE TREATMENT OF PHLEBOTHROMBOSIS AND THROMBOPHLEBITIS.]
Thrombosis
Perivascular Hyaluronidase With Alteplase as Treatment for Hyaluronic Acid Thrombosis.
The glycocalyx: a novel diagnostic and therapeutic target in sepsis.
The outpatient management of acute hemorrhoidal disease.
Tonsillitis
[Age related characteristics of hyaluronidase activity and morphohistochemical indices of palatine tonsil tissue in chronic toxico-allergic tonsillitis]
[The content of hyaluronidase and hyaluronic acid in the blood serum in chronic tonsillitis.]
[Thermal, leukocyte & erythrosedimentation changes after intratonsillar injections of hyaluronidase in febrile & nonfebrile patients with chronic tonsillitis.]
[Value of tonsillar tests in the diagnosis of focal tonsillitis, with special reference to the hyaluronidase test.]
Toxoplasmosis
[Effect of hyaluronidase on Toxoplasma gondii infection in mice.]
[Hyaluronidase and acid mucopolysaccharide activity in the placentas of women with toxoplasmosis]
Trismus
Effect of hyaluronidase on swelling and trismus after removal of impacted mandibular third molar teeth.
Hyaluronidase in relief of postoperative trismus, swelling, and pain. Separate injection in 150 oral surgical procedures.
Tuberculosis
Characterization of Rv0394c gene encoding hyaluronidase and chondrosulfatase from Mycobacterium tuberculosis.
Effect of streptomycin on hyaluronidase and local tuberculosis.
Hyaluronidase in tuberculosis.
[Activation of experimental tuberculosis in mice and guinea pigs by hyaluronidase.]
[Activity of serum hyaluronidase in children with tuberculosis and nontuberculos diseases]
[Effect of hyaluronidase on the concentration of S 35-labelled streptomycin in experimental tuberculosis]
[Influence on tuberculosis in the guinea pig of the addition of hyaluronidase to the infecting strain.]
[Isoniazid & hyaluronidase aerosol in bronchial tuberculosis.]
[Morpho-histochemical study of the processes of healing of tuberculosis during treatment with streptomycin and hyaluronidase]
[Practical application of labeled bacteria; study of the speed of dispersion of radiophosphorus-labeled Mycobacterium tuberculosis in the guinea pig; rapid dissemination of the bacteria in the presence or in the absence of hyaluronidase.]
[The effect of hyaluronidase on morphologic ractions in experimental tuberculosis]
[The use of hyaluronidase in experimental tuberculosis.]
[TREATMENT OF TUBERCULOSIS OF THE FEMALE GENITALIA WITH ANTIBACTERIAL PREPARATIONS AND THE ENZYME HYALURONIDASE.]
[Use of hyaluronidase in the complex treatment of tuberculosis]
Tuberculosis, Meningeal
Hyaluronidase as an adjuvant in the treatment of cranial arachnoiditis (hydrocephalus and optochiasmatic arachnoiditis) complicating tuberculous meningitis.
Use of intrathecal hyaluronidase in spinal arachnoiditis complicating tuberculous meningitis.
Use of intrathecal hyaluronidase in the management of tuberculous meningitis with hydrocephalus.
Tuberculosis, Pulmonary
[Antibiotic aerosols with hyaluronidase in pulmonary tuberculosis, results of fifteen months of use.]
[Antibiotics and hyaluronidase combined in aerosols in the treatment of lesions of pulmonary tuberculosis; 20 months' trial.]
[Changes in serum hyaluronidase activity in patients with infiltrative-pneumonic pulmonary tuberculosis]
[Effect of hyaluronidase on the permeability of the blood-tissue barriers in the complex therapy of patients with pulmonary tuberculosis]
[Hyaluronidase activity and hyaluronic acid in pregnant women and partiurients with pulmonary tuberculosis]
[Hyaluronidase in collapse therapy in pulmonary tuberculosis.]
[On the activity of hyaluronidase and antihyaluronidase in the blood in pulmonary tuberculosis.]
[The use of streptomycin aerosols and hyaluronidase in the treatment of chronic cavitary pulmonary tuberculosis.]
[Use of subcontinuous isoniazid and hyaluronidase aerosols in very grave pulmonary tuberculosis; a year and a half of tests.]
Tularemia
[Research on the pathogenesis of tularemia. I. On the production of the enzyme hyaluronidase by P. tularensis and other bacteria of the genus Pasteurella.]
Typhus, Endemic Flea-Borne
[Effect of hyaluronidase on the course of Rickettsia typhi infections in laboratory animals.]
Unconsciousness
Life-threatening complication of retrobulbar block. A hypothesis.
Urethral Stricture
Efficacy of holmium laser urethrotomy and intralesional injection of Santosh PGI tetra-inject (Triamcinolone, Mitomycin C, Hyaluronidase and N-acetyl cysteine) on the outcome of urethral strictures.
Urinary Bladder Calculi
The effect of hyaluronidase on induced vesical calculi in rats.
Urinary Bladder Neoplasms
A novel surface-enhanced Raman scattering-based ratiometric approach for detection of hyaluronidase in urine.
A ratiometric fluorescent probe for hyaluronidase detection via hyaluronan-induced formation of red-light emitting excimers.
Carbon Dot/Naphthalimide Based Ratiometric Fluorescence Biosensor for Hyaluronidase Detection.
Current bladder tumor tests: does their projected utility fulfill clinical necessity?
Detection of hyaluronidase RNA and activity in urine of schistosomal and non-schistosomal bladder cancer.
Direct detection of hyaluronidase in urine using cationic gold nanoparticles: a potential diagnostic test for bladder cancer.
Editorial Comment on: HYAL-1 Hyaluronidase: A Potential Prognostic Indicator for Progression to Muscle Invasion and Recurrence in Bladder Cancer.
Elevated tissue expression of hyaluronic acid and hyaluronidase validates the HA-HAase urine test for bladder cancer.
Expression of HYAL1 and survivin RNA as diagnostic molecular markers for bladder cancer.
HA-HAase urine test. A sensitive and specific method for detecting bladder cancer and evaluating its grade.
HYAL-1 Hyaluronidase: A Potential Prognostic Indicator for Progression to Muscle Invasion and Recurrence in Bladder Cancer.
HYAL1 hyaluronidase in prostate cancer: a tumor promoter and suppressor.
HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion.
HYAL1-v1, an alternatively spliced variant of HYAL1 hyaluronidase: a negative regulator of bladder cancer.
Hyaluronic acid/ Hyaluronidase as biomarkers for bladder cancer: a diagnostic meta-analysis.
Identification of bladder tumor-derived hyaluronidase: its similarity to HYAL1.
Intravesical chemotherapy of superficial bladder tumors in a controlled trial with cis-platinum versus cis-platinum plus hyaluronidase.
Metaphylactic effect of mitomycin C with and without hyaluronidase after transurethral resection of bladder cancer: randomized trial.
Mitomycin C plasma levels after intravesical instillation with and without hyaluronidase.
One-step facile synthesis of hyaluronic acid functionalized fluorescent gold nanoprobes sensitive to hyaluronidase in urine specimen from bladder cancer patients.
Proteomic assays for the detection of urothelial cancer.
Regulation of hyaluronidase activity by alternative mRNA splicing.
Secretion of bladder tumor-derived hyaluronidase activity by invasive bladder tumor cells.
Spectrophotometry in modular microfluidic architectures.
The diagnostic efficacy of urinary survivin and hyaluronidase mRNA as urine markers in patients with bladder cancer.
Topical chemoprophylaxis of superficial bladder cancer with mitomycin C and adjuvant hyaluronidase.
Tumor-derived hyaluronidase: a diagnostic urine marker for high-grade bladder cancer.
Urinary hyaluronic acid and hyaluronidase: markers for bladder cancer detection and evaluation of grade.
Urinary retinoic acid receptor-?2 gene promoter methylation and hyaluronidase activity as noninvasive tests for diagnosis of bladder cancer.
Urine-based biomarkers for the early detection and surveillance of non-muscle invasive bladder cancer.
[Hyaluronic acid and hyaluronidase. 2 new bladder carcinoma markers]
Urinary Calculi
Experimental evaluation of hyaluronidase in prevention and dissolution of urinary calculi.
Hyaluronidase and urinary stone.
HYALURONIDASE and urinary stones.
Observations on the effect of hyaluronidase on urinary calculi.
Urinary calculi in livestock; a new concept of its etiology and possible prevention with hyaluronidase.
Use of hyaluronidase to prevent urinary calculi; report of a case in which stone recurrence was facilitated by hyaluronidase therapy.
[Experimental studies on the effect of hyaluronidase on the formation of urinary calculi.]
[Hyaluronidase and urinary calculus formation.]
Urolithiasis
Experimental urolithiasis. VI. Failure of hyaluronidase to inhibit growth of stones on foreign bodies in the rat.
Urticaria
Acute urticaria caused by the injection of goat-derived hyaluronidase.
Studies on mucopolysaccharide in skin diseases. I. Treatment of urticaria pigmentosa with hyaluronidase.
Urticaria Pigmentosa
Studies on mucopolysaccharide in skin diseases. I. Treatment of urticaria pigmentosa with hyaluronidase.
[Mastocytoma and urticaria pigmentosa; attempts at injection in situ of hyaluronidase.]
Uterine Cervical Neoplasms
Hyaluronidase activity in gynaecological cancer tissues with different metastatic forms.
Uterine Cervicitis
[Combination of hyaluronidase with local administration of antibiotics in the treatment of cervicitis.]
Uterine Hemorrhage
[The levels of hyaluronidase and sialic acids in the blood serum of women with dysfunctional uterine hemorrhage during the climacteric]
Uterine Inertia
[Application of hyaluronidase in labor induction in cases of uterine inertia.]
[Content of hyaluronic acid, hyaluronidase and antihyaluronidase in women with primary uterine inertia]
Vaccinia
Effect of cortisone and hyaluronidase on the production of hemagglutinin of influenza and vaccinia viruses in suspended cell cultures.
Effect of hyaluronidase on reaction of rabbits to intradermal inoculations of vaccinia virus.
Venous Thrombosis
Treatment of edema caused by chronic phlebothrombosis and other peripheral vascular diseases with hyaluronidase.
[HEPARINOID AND HYALURONIDASE COMBINATION IN THE TREATMENT OF PHLEBOTHROMBOSIS AND THROMBOPHLEBITIS.]
[Use of hyaluronidase to correct hyaluronic acid injections in aesthetic medicine].
Virus Diseases
Bacterial enzyme in viral infections: a new concept. The possible role of hyaluronidase in herpes simplex virus keratitis.
Pneumococcal surface protein A contributes to secondary Streptococcus pneumoniae infection after influenza virus infection.
Vision Disorders
Clinical Observations and the Anatomical Basis of Blindness After Facial Hyaluronic Acid Injection.
Vitreoretinopathy, Proliferative
Inhibition of preretinal proliferation by free radical scavengers in an experimental model of tractional retinal detachment.
Vitreous Detachment
Efficacy and safety of enzymatic posterior vitreous detachment by intravitreal injection of hyaluronidase.
In Vivo Retinal Vein Bypass Surgery in a Porcine Model.
Induction of vitreolysis and vitreous detachment with hyaluronidase and perfluoropropane gas.
Intravitreal injection of hyaluronidase cannot induce posterior vitreous detachment in the rabbit.
Pharmacological vitrectomy.
PVD following plasmin but not hyaluronidase: implications for combination pharmacologic vitreolysis therapy.
[An experimental study on dissolving and detaching vitreoretinal interface with enzymes]
[Experimental induction of posterior vitreous detachment in rabbits with hyaluronidase and perfluoroethane (C2F6)]
[Pharmacologic vitieolysis in diabetic rats]
Vitreous Hemorrhage
Hyaluronidase: a review of approved formulations, indications and off-label use in chronic pain management.
Pharmacologic Vitreolysis in Diabetic Retinopathy.
Pharmacological vitrectomy.
Pooled efficacy results from two multinational randomized controlled clinical trials of a single intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage.
Predicting response of vitreous hemorrhage after intravitreous injection of highly purified ovine hyaluronidase (Vitrase) in patients with diabetes.
Retinal vasculopathy in Fanconi anemia.
Safety results of two phase III trials of an intravitreous injection of highly purified ovine hyaluronidase (Vitrase) for the management of vitreous hemorrhage.
Vitreous hemorrhage absorption; experimental study on rabbit eyes of the effects of intravitreal hyaluronidase and streptokinase-strptodornase and on the influence of ACTH and cortisone.
Werner Syndrome
The molecular weight-dependent distribution of urinary glycosaminoglycans in Werner's syndrome.
Urinary acidic glycosaminoglycans in Werner's syndrome.
Urinary excretion of macromolecular acidic glycosaminoglycans in Werner's syndrome.
Whooping Cough
Differential purification of autocrine motility factor derived from a murine protein-free fibrosarcoma.
Wilms Tumor
Hyaluronidase levels in urine from Wilms' tumor patients.