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Information on EC 3.2.1.36 - hyaluronoglucuronidase and Organism(s) Hirudo nipponia and UniProt Accession X4Y2L4

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Hirudo nipponia
UNIPROT: X4Y2L4 not found.
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Word Map
The taxonomic range for the selected organisms is: Hirudo nipponia
The enzyme appears in selected viruses and cellular organisms
Synonyms
hyaluronidase, haase, hyase, vest2b, lhase, haase-b, vest2a, hyaluronate lyase hylp2, hyaluronoglucuronidase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hyaluronidase
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glucuronoglucosaminoglucan hyaluronate lyase
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hyaluronidase
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orgelase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of O-glycosyl bond
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-
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SYSTEMATIC NAME
IUBMB Comments
hyaluronate 3-glycanohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
37288-34-9
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
hyaluronan + H2O
hyaluronan tetrasaccharides + hyaluronan hexasaccharides
show the reaction diagram
hyaluronan is mainly degraded into hyaluronan tetrasaccharides and hyaluronan hexasaccharides. The proportion of hyaluronan tetrasaccharides and hyaluronan hexasaccharides is accurately controlled by amount of enzyme. Higher yield of hyaluronan tetrasaccharides is achieved with higher activity of the enzyme
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?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SwissProt
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
LHYAL_HIRNI
489
0
55090
Swiss-Prot
other Location (Reliability: 2)
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lv, M.; Wang, M.; Cai, W.; Hao, W.; Yuan, P.; Kang, Z.
Characterisation of separated end hyaluronan oligosaccharides from leech hyaluronidase and evaluation of angiogenesis
Carbohydr. Polym.
142
309-316
2016
Hirudo nipponia (X4Y2L4)
Manually annotated by BRENDA team