Reference on EC 3.2.1.207 - mannosyl-oligosaccharide alpha-1,3-glucosidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kaushal, G.P.; Pan, Y.T.; Tropea, J.E.; Mitchell, M.; Liu, P.; Elbein, A.D.
Selective inhibition of glycoprotein-processing enzymes. Differential inhibition of glucosidases I and II in cell culture
J. Biol. Chem.
263
17278-17283
1988
Vigna radiata
Saxena, S.; Shailubhai, K.; Dong-Yu, B.; Vijay, I.K.
Purification and characterization of glucosidase II involved in N-linked glycoprotein processing in bovine mammary gland
Biochem. J.
247
563-570
1987
Bos taurus
Strous, G.J.; Van Kerkhof, P.; Brok, R.; Roth, J.; Brada, D.
Glucosidase II, a protein of the endoplasmic reticulum with high mannose oligosaccharide chains and a rapid turnover
J. Biol. Chem.
262
3620-3625
1987
Rattus norvegicus
Lucocq, J.M.; Brada, D.; Roth J.
Immunolocalization of the oligosaccharide trimming enzyme glucosidase II
J. Cell Biol.
102
2137-2146
1986
Sus scrofa
Hino, Y.; Rothman, J.E.
Glucosidase II, a glycoprotein of the endoplasmic reticulum membrane. Proteolytic cleavage into enzymatically active fragments
Biochemistry
24
800-805
1985
Rattus norvegicus
Brada, D.; Dubach, U.C.
Isolation of a homogeneous glucosidase II from pig kidney microsomes
Eur. J. Biochem.
141
149-156
1984
Sus scrofa
Tabas, I.; Kornfeld, S.
N-Asparagine-linked oligosaccharides: processing
Methods Enzymol.
83
416-429
1982
Bos taurus
Burns, D.M.; Touster, O.
Purification and characterization of glucosidase II, an endoplasmic reticulum hydrolase involved in glycoprotein biosynthesis
J. Biol. Chem.
257
9991-10000
1982
Rattus norvegicus
-
Grinna, L.S.; Robbins, P.W.
Substrate specificities of rat liver microsomal glucosidases which process glycoproteins
J. Biol. Chem.
255
2255-2258
1980
Rattus norvegicus
Alonso, J.F.; Santa-Cecilia, A.; Calvo, P.
Effect of bromoconduritol on glucosidase II from rat liver, a new kinetic model for the binding and hydrolysis of the substrate
Eur. J. Biochem.
215
37-42
1993
Rattus norvegicus
Kaushal, G.P.; Zeng, Y.; Elbein, A.D.
Biosynthesis of glucosidase II in suspension-cultured soybean cells
J. Biol. Chem.
268
14536-14542
1993
Glycine max, Vigna radiata
Trombetta, E.S.; Simons, J.F.; Helenius, A.
Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit
J. Biol. Chem.
271
27509-27516
1996
Rattus norvegicus
D'Alessio, C.; Fernndez, F.; Trombetta, E.S.; Parodi, A.J.
Genetic evidence for the heterodimeric structure of glucosidase II: the effect of disrupting the subunit-encoding genes on glycoprotein folding
J. Biol. Chem.
274
25899-25905
1996
Schizosaccharomyces pombe
Santa-Cecilia, A.; Alonso, J.F.; Calvo, P.
Glucosidase II from control and ethanol-treated rats: purification and properties
Biol. Chem.
372
373-380
1991
Rattus norvegicus
Alonso, J.F.; Santa-Cecilia, A.; Chinchetru, M.A.; Calvo, P.
Characterization of the maltase activity of glucosidase II from rat liver: kinetic model
Biol. Chem.
374
977-982
1993
Rattus norvegicus
Hentges, A.; Bause, E.
Affinity purification and characterization of glucosidase II from pig liver
Biol. Chem.
378
1031-1038
1997
Sus scrofa
Takeuchi, M.; Kamata, K.; Yoshida, M.; Kameda, Y.; Matsui, K.
Inhibitory effect of pseudo-aminosugars on oligosaccharide glucosidases I and II and on lysosomal alpha-glucosidase from rat liver
J. Biochem.
108
42-46
1990
Rattus norvegicus
Brada, D.; Kerjaschki, D.; Roth, J.
Call type-specific post-Golgi apparatus localization of a "resident" endoplasmic reticulum glycoprotein, glucosidase II
J. Cell Biol.
110
309-318
1990
Sus scrofa
Alonso, J.F.; Santa-Cecilia, A.; Calvo, P.
Glucosidase II from rat liver microsomes: kinetic model for binding and hydrolysis
Biochem. J.
278
721-727
1991
Rattus norvegicus
-
Treml, K.; Meimaroglou, D.; Hentges, A.; Bause, E.
The alpha- and beta-subunits are required for expression of catalytic activity in the hetero-dimeric glucosidase II complex from human liver
Glycobiology
10
493-502
2000
Homo sapiens (Q14697)
Kaushal, G.P.; Pastuszak, I.; Hatanka, K.; Elbein, A.D.
Purification to homogeneity and properties of glucosidase II from mung bean seedlings and suspension-cultured soybean cells
J. Biol. Chem.
265
16271-16279
1990
Vigna radiata
Roth, J.; Ziak, M.; Zuber, C.
The role of glucosidase II and endomannosidase in glucose trimming of asparagine-linked oligosaccharides
Biochimie
85
287-294
2003
Bos taurus, Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Trombetta, E.S.; Fleming, K.G.; Helenius, A.
Quaternary and domain structure of glycoprotein processing glucosidase II
Biochemistry
40
10717-10722
2001
Rattus norvegicus
Hirano, K.; Ziak, M.; Kamoshita, K.; Sukenaga, Y.; Kametani, S.; Shiga, Y.; Roth, J.; Akanuma, H.
N-linked oligosaccharide processing enzyme glucosidase II produces 1,5-anhydrofructose as a side product
Glycobiology
10
1283-1289
2000
Rattus norvegicus, Sus scrofa
Arendt, C.W.; Ostergaard, H.L.
Two distinct domains of the beta-subunit of glucosidase II interact with the catalytic alpha-subunit
Glycobiology
10
487-492
2000
Mus musculus
Pelletier, M.F.; Marcil, A.; Sevigny, G.; Jakob, C.A.; Tessier, D.C.; Chevet, E.; Menard, R.; Bergeron, J.J.M.; Thomas, D.Y.
The heterodimeric structure of glucosidase II is required for its activity, solubility, and localization in vivo
Glycobiology
10
815-827
2000
Homo sapiens (P14314), Homo sapiens (Q14697)
Baldwin, T.A.; Gogela-Spehar, M.; Ostergaard, H.L.
Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction
J. Biol. Chem.
275
32071-32076
2000
Mus musculus
Hakamata, W.; Muroi, M.; Nishio, T.; Oku, T.; Takatsuki, A.
Recognition properties of processing alpha-glucosidase I and alpha-glucosidase II
J. Carbohydr. Chem.
23
27-39
2004
Rattus norvegicus
-
Geysens, S.; Pakula, T.; Uusitalo, J.; Dewerte, I.; Penttilae, M.; Contreras, R.
Cloning and characterization of the glucosidase II alpha subunit gene of Trichoderma reesei: a frameshift mutation results in the aberrant glycosylation profile of the hypercellulolytic strain Rut-C30
Appl. Environ. Microbiol.
71
2910-2924
2005
Trichoderma reesei, Trichoderma reesei RUT C-30
Gamberucci, A.; Konta, L.; Colucci, A.; Giunti, R.; Magyar, J.E.; Mandl, J.; Banhegyi, G.; Benedetti, A.; Csala, M.
Green tea flavonols inhibit glucosidase II
Biochem. Pharmacol.
72
640-646
2006
Rattus norvegicus
Feng, J.; Romaniouk, A.V.; Samal, S.K.; Vijay, I.K.
Processing enzyme glucosidase II: proposed catalytic residues and developmental regulation during the ontogeny of the mouse mammary gland
Glycobiology
14
909-921
2004
Mus musculus (Q8BHN3)
Jones, D.C.; Mehlert, A.; Guether, M.L.; Ferguson, M.A.
Deletion of the glucosidase II gene in Trypanosoma brucei reveals novel N-glycosylation mechanisms in the biosynthesis of variant surface glycoprotein
J. Biol. Chem.
280
35929-35942
2005
Trypanosoma brucei
Wilkinson, B.M.; Purswani, J.; Stirling, C.J.
Yeast GTB1 encodes a subunit of glucosidase II required for glycoprotein processing in the endoplasmic reticulum
J. Biol. Chem.
281
6325-6333
2006
Saccharomyces cerevisiae
Schirawski, J.; Boehnert, H.U.; Steinberg, G.; Snetselaar, K.; Adamikowa, L.; Kahmann, R.
Endoplasmic reticulum glucosidase II is required for pathogenicity of Ustilago maydis
Plant Cell
17
3532-3543
2005
Ustilago maydis
Totani, K.; Ihara, Y.; Matsuo, I.; Ito, Y.
Effects of macromolecular crowding on glycoprotein processing enzymes
J. Am. Chem. Soc.
130
2101-2107
2008
Rattus norvegicus
Totani, K.; Ihara, Y.; Matsuo, I.; Ito, Y.
Substrate specificity analysis of endoplasmic reticulum glucosidase II using synthetic high mannose-type glycans
J. Biol. Chem.
281
31502-31508
2006
Rattus norvegicus
Bosis, E.; Nachliel, E.; Cohen, T.; Takeda, Y.; Ito, Y.; Bar-Nun, S.; Gutman, M.
Endoplasmic Reticulum Glucosidase II is inhibited by its end products
Biochemistry
47
10970-10980
2008
Rattus norvegicus
Soussillane, P.; D'Alessio, C.; Paccalet, T.; Fitchette, A.-C.; Parodi, A.J.; Williamson, R.; Plasson, C.; Faye, L.; Gomord, V.
N-glycan trimming by glucosidase II is essential for Arabidopsis development
Glycoconj. J.
26
597-607
2009
Arabidopsis thaliana (Q9FN05)
Hu, D.; Kamiya, Y.; Totani, K.; Kamiya, D.; Kawasaki, N.; Yamaguchi, D.; Matsuo, I.; Matsumoto, N.; Ito, Y.; Kato, K.; Yamamoto, K.
Sugar-binding activity of the MRH domain in the ER alpha-glucosidase II beta subunit is important for efficient glucose trimming
Glycobiology
19
1127-1135
2009
Homo sapiens
Watanabe, T.; Totani, K.; Matsuo, I.; Maruyama, J.; Kitamoto, K.; Ito, Y.
Genetic analysis of glucosidase II beta-subunit in trimming of high-mannose-type glycans
Glycobiology
19
834-840
2009
Aspergillus oryzae, Aspergillus oryzae RIB 40
Stigliano, I.D.; Caramelo, J.J.; Labriola, C.A.; Parodi, A.J.; DAlessio, C.
Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals
Mol. Biol. Cell
20
3974-3984
2009
Rattus norvegicus, Schizosaccharomyces pombe
Lu, X.; Tintor, N.; Mentzel, T.; Kombrink, E.; Boller, T.; Robatzek, S.; Schulze-Lefert, P.; Saijo, Y.
Uncoupling of sustained MAMP receptor signaling from early outputs in an Arabidopsis endoplasmic reticulum glucosidase II allele
Proc. Natl. Acad. Sci. USA
106
22522-22527
2009
Arabidopsis thaliana
Torres-Rodriguez, B.I.; Flores-Berrout, K.; Villagomez-Castro, J.C.; Lopez-Romero, E.
Purification and partial biochemical characterization of a membrane-bound type II-like alpha-glucosidase from the yeast morphotype of Sporothrix schenckii
Antonie van Leeuwenhoek
101
313-322
2012
Sporothrix schenckii, Sporothrix schenckii EH206
Miyagawa, A.; Totani, K.; Matsuo, I.; Ito, Y.
Promiscuous activity of ER glucosidase II discovered through donor specificity analysis of UGGT
Biochem. Biophys. Res. Commun.
403
322-328
2010
Rattus norvegicus
Takeda, Y.; Totani, K.; Matsuo, I.; Ito, Y.
The action of bromoconduritol on ER glucosidase II
Bioorg. Med. Chem. Lett.
20
5357-5359
2010
Rattus norvegicus
Anji, A.; Kumari, M.
A cis-acting region in the N-methyl-D-aspartate R1 3'-untranslated region interacts with the novel RNA-binding proteins beta subunit of alpha glucosidase II and annexin A2 - effect of chronic ethanol exposure in vivo
Eur. J. Neurosci.
34
1200-1211
2011
Mus musculus
Stigliano, I.D.; Alculumbre, S.G.; Labriola, C.A.; Parodi, A.J.; DAlessio, C.
Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo
Mol. Biol. Cell
22
1810-1823
2011
Leishmania mexicana, Schizosaccharomyces pombe
von Numers, N.; Survila, M.; Aalto, M.; Batoux, M.; Heino, P.; Palva, E.T.; Li, J.
Requirement of a homolog of glucosidase II beta-subunit for EFR-mediated defense signaling in Arabidopsis thaliana
Mol. Plant
3
740-750
2010
Arabidopsis thaliana
Watanabe, S.; Kakudo, A.; Ohta, M.; Mita, K.; Fujiyama, K.; Inumaru, S.
Molecular cloning and characterization of the alpha-glucosidase II from Bombyx mori and Spodoptera frugiperda
Insect Biochem. Mol. Biol.
43
319-327
2013
Bombyx mori (L8B6C5), Bombyx mori (L8B8U1), Spodoptera frugiperda (L8B8V1)
Olson, L.J.; Orsi, R.; Alculumbre, S.G.; Peterson, F.C.; Stigliano, I.D.; Parodi, A.J.; DAlessio, C.; Dahms, N.M.
Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum
J. Biol. Chem.
288
16460-16475
2013
Schizosaccharomyces pombe
Anji, A.; Miller, H.; Raman, C.; Phillips, M.; Ciment, G.; Kumari, M.
Expression of alpha-subunit of alpha-glucosidase II in adult mouse brain regions and selected organs
J. Neurosci. Res.
93
82-93
2015
Mus musculus (Q8BHN3), Mus musculus C57BL/6 (Q8BHN3)
Jiang, J.; Kuo, C.; Wu, L.; Franke, C.; Kallemeijn, W.; Florea, B.; Van Meel, E.; Van Der Marel, G.; Codee, J.; Boot, R.; Davies, G.; Overkleeft, H.; Aerts, J.
Detection of active mammalian GH31 alpha-glucosidases in health and disease using in-class, broad-spectrum activity-based probes
ACS Cent. Sci.
2
351-358
2016
Homo sapiens
Kiappes, J.; Hill, M.; Alonzi, D.; Miller, J.; Iwaki, R.; Sayce, A.; Caputo, A.; Kato, A.; Zitzmann, N.
ToP-DNJ, a selective inhibitor of endoplasmic reticulum alpha-glucosidase II exhibiting antiflaviviral activity
ACS Chem. Biol.
13
60-65
2018
Homo sapiens
Ebert, D.; Bush, J.; Dimond, R.; Cardelli, J.
Biogenesis of lysosomal enzymes in the alpha-glucosidase II-deficient modA mutant of Dictyostelium discoideum Retention of alpha-1,3-linked glucose on N-linked oligosaccharides delays intracellular transport but does not alter sorting of alpha-mannosidase or beta-glucosidase
Arch. Biochem. Biophys.
273
479-490
1989
Dictyostelium discoideum (Q94502)
Ziak, M.; Meier, M.; Etter, K.; Roth, J.
Two isoforms of trimming glucosidase II exist in mammalian tissues and cell lines but not in yeast and insect cells
Biochem. Biophys. Res. Commun.
280
363-367
2001
Rattus norvegicus, Sus scrofa
Olson, L.; Orsi, R.; Peterson, F.; Parodi, A.; Kim, J.; DAlessio, C.; Dahms, N.
Crystal structure and functional analyses of the lectin domain of glucosidase II insights into oligomannose recognition
Biochemistry
54
4097-4111
2015
Schizosaccharomyces pombe (Q9USH8), Schizosaccharomyces pombe 972 (Q9USH8)
Takeda, Y.; Totani, K.; Matsuo, I.; Ito, Y.
The action of bromoconduritol on ER glucosidase II
Bioorg. Med. Chem. Lett.
20
5357-5359
2010
Rattus norvegicus
Cumpstey, I.; Ramstadius, C.; Eszter Borbas, K.; Alonzi, D.; Butters, T.
Synthesis and alpha-glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis
Bioorg. Med. Chem. Lett.
21
5219-5223
2011
Rattus norvegicus
Okuyama, M.; Miyamoto, M.; Matsuo, I.; Iwamoto, S.; Serizawa, R.; Tanuma, M.; Ma, M.; Klahan, P.; Kumagai, Y.; Tagami, T.; Kimura, A.
Substrate recognition of the catalytic alpha-subunit of glucosidase II from Schizosaccharomyces pombe
Biosci. Biotechnol. Biochem.
81
1503-1511
2017
Schizosaccharomyces pombe (Q9US55), Schizosaccharomyces pombe 972 (Q9US55)
Kaewmuangmoon, J.; Kilaso, M.; Leartsakulpanich, U.; Kimura, K.; Kimura, A.; Chanchao, C.
Expression of a secretory beta-glucosidase II from Apis cerana indica in Pichia pastoris and its characterization
BMC Biotechnol.
13
16
2013
Apis cerana indica (J9SJ08)
Mora-Montes, H.; Bates, S.; Netea, M.; Diaz-Jimenez, D.; Lopez-Romero, E.; Zinker, S.; Ponce-Noyola, P.; Kullberg, B.; Brown, A.; Odds, F.; Flores-Carreon, A.; Gow, N.
Endoplasmic reticulum alpha-glycosidases of Candida albicans are required for N glycosylation, cell wall integrity, and normal host-fungus interaction
Eukaryot. Cell
6
2184-2193
2007
Candida albicans (Q5A4X3), Candida albicans ATCC MYA-2876 (Q5A4X3)
-
Torre-Bouscoulet, M.; Lopez-Romero, E.; Balcazar-Orozco, R.; Calvo-Mendez, C.; Flores-Carreon, A.
Partial purification and biochemical characterization of a soluble alpha-glucosidase II-like activity from Candida albicans
FEMS Microbiol. Lett.
236
123-128
2004
Candida albicans (Q2V621), Candida albicans ATCC 26555 (Q2V621)
Robledo-Ortiz, C.; Flores-Carreon, A.; Hernandez-Cervantes, A.; Alvarez-Vargas, A.; Lee, K.; Diaz-Jimenez, D.; Munro, C.; Cano-Canchola, C.; Mora-Montes, H.
Isolation and functional characterization of Sporothrix schenckii ROT2, the encoding gene for the endoplasmic reticulum glucosidase II
Fungal Biol.
116
910-918
2012
Sporothrix schenckii (H9TU28), Sporothrix schenckii
Watanabe, S.; Kakudo, A.; Ohta, M.; Mita, K.; Fujiyama, K.; Inumaru, S.
Molecular cloning and characterization of the alpha-glucosidase II from Bombyx mori and Spodoptera frugiperda
Insect Biochem. Mol. Biol.
43
319-327
2013
Bombyx mori (L8B8U1 and L8B6C5), Spodoptera frugiperda (L8B8V1)
Anji, A.; Miller, H.; Raman, C.; Phillips, M.; Ciment, G.; Kumari, M.
Expression of alpha subunit of alpha-glucosidase II in adult mouse brain regions and selected organs
J. Neurosci. Res.
93
82-93
2015
Mus musculus
Taylor, M.; Ross, H.; McRae, D.; Stewart, D.; Roberts, I.; Duncan, G.; Wright, F.; Millam, S.; Davies, H.
A potato α-glucosidase gene encodes a glycoprotein-processing alpha-glucosidase II-like activity. Demonstration of enzyme activity and effects of down-regulation in transgenic plants
Plant J.
24
305-316
2000
Solanum tuberosum (O24375)
Caputo, A.; Alonzi, D.; Marti, L.; Reca, I.; Kiappes, J.; Struwe, W.; Cross, A.; Basu, S.; Lowe, E.; Darlot, B.; Santino, A.; Roversi, P.; Zitzmann, N.
Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals
Proc. Natl. Acad. Sci. USA
113
E4630-E4638
2016
Mus musculus (Q8BHN3)
Caputo, A.; Alonzi, D.; Kiappes, J.; Struwe, W.; Cross, A.; Basu, S.; Darlot, B.; Roversi, P.; Zitzmann, N.
Structural insights into the broad-spectrum antiviral target endoplasmic reticulum alpha-glucosidase II
Adv. Exp. Med. Biol.
1062
265-276
2018
Mus musculus (Q8BHN3), Mus musculus
Levy-Ontman, O.; Fisher, M.; Shotland, Y.; Tekoah, Y.; Malis Arad, S.
Insight into glucosidase II from the red marine microalga Porphyridium sp. (Rhodophyta)
J. Phycol.
51
1075-1087
2015
Porphyridium sp.
Satoh, T.; Toshimori, T.; Noda, M.; Uchiyama, S.; Kato, K.
Interaction mode between catalytic and regulatory subunits in glucosidase II involved in ER glycoprotein quality control
Protein Sci.
25
2095-2101
2016
Thermochaetoides thermophila (G0SG42 and G0S9M2), Thermochaetoides thermophila DSM 1495 (G0SG42 and G0S9M2)
Satoh, T.; Toshimori, T.; Yan, G.; Yamaguchi, T.; Kato, K.
Structural basis for two-step glucose trimming by glucosidase II involved in ER glycoprotein quality control
Sci. Rep.
6
20575
2016
Thermochaetoides thermophila (G0SG42 and G0S9M2), Thermochaetoides thermophila DSM 1495 (G0SG42 and G0S9M2)
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