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Information on EC 3.2.1.11 - dextranase
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EC Tree
3.2.1.11 dextranaseSpecify your search results
Word Map
- 3.2.1.11
- dextrans
- streptococcus
-
dental
- glucans
- plaque
- penicillium
- caries
- leuconostoc
- sobrinus
- dextransucrase
- isomaltose
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water-insoluble
-
cariogenic
- mesenteroides
-
colon-specific
- lipomyces
- downei
- sanguis
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glucosyltransferases
- funiculosum
- salivarius
- mutanase
- synthesis
- medicine
- starkeyi
- isomaltotriose
- agriculture
- degradation
- nutrition
- drug development
- isomalto-oligosaccharides
- biotechnology
- food industry
-
glucan-binding
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
dextranase, endodextranase, endo-dextranase, extracellular dextranase, aodex, alpha-glucanase, dex410, tpdex, smdex, dex49a, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
1,6-alpha-D-glucan-6-glucanohydrolase
6-alpha-D-glucan 6-glucanohydrolase
alpha-1,6-D-glucan 6-glucanohydrolase
alpha-1,6-D-glucan-6-glucanohydrolase
Alpha-1,6-glucan-6-glucanohydrolase
alpha-D-1,6-glucan-6-glucanohydrolase
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AODex
Dex
DexA
dextran hydrolase
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dextranase
dextranase DL 2
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DL 2
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endo-dextranase
endodextranase
Fjoh_4430
LSD1
SmDex
Teth39_0264
TLDex
TPDex
additional information
Alpha-1,6-glucan-6-glucanohydrolase
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endo-dextranase
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endodextranase
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additional information
the enzyme belongs to the glycoside hydrolase family (GH) 66
additional information
the enzyme belongs to the glycoside hydrolase family (GH) 66
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
dextran + H2O = dextran fragment 1 + dextran fragment 2
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hydrolysis of O-glycosyl bond
hydrolysis of O-glycosyl bond
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
6-alpha-D-glucan 6-glucanohydrolase
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CAS REGISTRY NUMBER
COMMENTARY
9025-70-1
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-sindacene-3-propionic acid, succinimidyl ester)-quenched dextran + H2O
?
dextran + H2O
D-glucose + isomaltose + isomalto-oligosaccharides
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-
-
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?
dextran + H2O
isomaltose + isomaltotriose + D-glucose + low molecular-mass polysaccharides
dextran + H2O
isomaltotetraose
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plus small amounts of cycloisomaltooligosaccharides with a degree of polymerization of 714
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?
dextran + H2O
isomaltotetraose + cycloisomaltooligosaccharides
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main products are isomaltotetraose and small amounts of cycloisomaltooligosaccharides with a degree of polymerization of 7-14
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?
dextran T100 + H2O
isomaltose + isomaltotriose + isomaltooligosaccharides
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?
dextran T2000 + H2O
isomaltooligosaccharides
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very high hydrolytic affinity, 100% activity with 3% (w/v) dextran T2000
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?
dextran T2000 + H2O
isomaltotriose + isomaltotetraose + isomaltopentaose
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main end-products
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?
dextran T3 + H2O
isomaltose + isomaltotriose + D-glucose
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65.17% activity compared to dextran T70
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?
dextran T40 + H2O
isomaltose + isomaltotriose
88% activity compared to dextran T70
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?
dextran T40 + H2O
isomaltose + isomaltotriose + D-glucose
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98.5% activity compared to dextran T70
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?
dextran T40 + H2O
isomaltose + isomaltotriose + isomaltooligosaccharides
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-
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?
dextran T5 + H2O
isomaltose + isomaltotriose + D-glucose
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65.54% activity compared to dextran T70
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?
dextran T500 + H2O
isomaltose + isomaltotriose
96% activity compared to dextran T70
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?
dextran T500 + H2O
isomaltose + isomaltotriose + D-glucose
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99.62% activity compared to dextran T70
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?
dextran T500 + H2O
isomaltose + isomaltotriose + isomaltooligosaccharides
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90.78% activity compared to dextran T250
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?
dextran T60-90 + H2O
isomaltose + isomaltotriose + isomaltooligosaccharides
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90.19% activity compared to dextran T250
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?
dextran T70 + H2O
isomaltooligosaccharides
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96% of the activity with dextran T500
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?
dextran T70 + H2O
isomaltose + isomaltotriose
100% activity
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?
dextran T70 + H2O
isomaltose + isomaltotriose + D-glucose
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100% activity
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?
dextran T70 + H2O
isomaltose + isomaltotriose + isomaltooligosaccharides
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?
glucan + H2O
D-glucose + isomaltose + isomaltotriose + ?
Achaetomiella gracilis
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from Streptococcus sobrinus K1-R
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?
isomaltohexaose + H2O
D-glucose + isomaltose + isomaltotriose + isomaltotetraose + isomaltopentaose
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?
Sephacryl S-300 + H2O
?
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4.02% activity compared to dextran T250
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?
(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-sindacene-3-propionic acid, succinimidyl ester)-quenched dextran + H2O
?
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?
(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-sindacene-3-propionic acid, succinimidyl ester)-quenched dextran + H2O
?
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?
4-nitrophenyl alpha-isomaltopentoside + H2O
?
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?
4-nitrophenyl alpha-isomaltotetraoside + H2O
?
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?
alternan + H2O
?
15% activity compared to dextran T70
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?
alternan + H2O
?
15% activity compared to dextran T70
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
-
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
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Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
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Asp-453 and Trp-793 residues are critical for enzyme activity
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?
blue-dextran + H2O
?
Asp-453 and Trp-793 residues are critical for enzyme activity
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?
dextran + H2O
?
-
extent of hydrolysis of 5-aminosalicylic acid-dextran conjugates (secondary amines) by dextranase is in part controlled by the degree of oxidation and by the amount of conjugated 5-aminosalicylic acid. Less oxidised dextrans (12%) conjugating proportionally less 5-aminosalicylic acid are successfully hydrolysed by dextranase
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?
dextran + H2O
?
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extent of hydrolysis of 5-aminosalicylic acid-dextran conjugates (secondary amines) by dextranase is in part controlled by the degree of oxidation and by the amount of conjugated 5-aminosalicylic acid. Less oxidised dextrans (12%) conjugating proportionally less 5-aminosalicylic acid are successfully hydrolysed by dextranase
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?
dextran + H2O
?
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substrate dextran T-20 98.9%, dextran 20000 91.3%, dextran T-70 98.3%, dextran T-500 85.1%, dextran T-2000 86.7% relative activity, respectively
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?
dextran + H2O
?
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substrate dextran T-20 98.9%, dextran 20000 91.3%, dextran T-70 98.3%, dextran T-500 85.1%, dextran T-2000 86.7% relative activity, respectively
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?
dextran + H2O
D-glucose + isomaltose + isomaltooligosaccharides
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?
dextran + H2O
D-glucose + isomaltose + isomaltooligosaccharides
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?
dextran + H2O
D-glucose + isomaltotriose + isomaltose + isomaltooligosaccharide
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?
dextran + H2O
D-glucose + isomaltotriose + isomaltose + isomaltooligosaccharide
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?