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Disease on EC 3.1.6.2 - steryl-sulfatase

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DISEASE
TITLE OF PUBLICATION
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3(or 17)beta-hydroxysteroid dehydrogenase deficiency
Isolated dehydroepiandrosterone sulphate hypersecretion: a case report.
Abortion, Spontaneous
Elevated levels of dehydroepiandrosterone as a potential mechanism of dendritic cell impairment during pregnancy.
Unconjugated estriol as an indication for prenatal diagnosis of steroid sulfatase deficiency by in situ hybridization.
Abscess
Serum testosterone, DHEAS, and prolactin levels in patients with a Bartholin's abscess.
Acanthosis Nigricans
Correlation of Cutaneous Manifestations with Body Mass Index, Blood Glucose, and Hormonal Levels in Patients with Polycystic Ovarian Disease.
Acne Vulgaris
A randomized controlled trial of second- versus third-generation oral contraceptives in the treatment of acne vulgaris.
Androgenicity and fertility treatment in women with unexplained infertility.
CAG repeat polymorphism in androgen receptor gene is not directly associated with polycystic ovary syndrome but influences serum testosterone levels.
Clinical, ultrasound and hormonal markers of androgenicity in acne vulgaris.
Comparison of adrenocortical steroidogenesis in women with post-adolescent severe acne and polycystic ovary syndrome.
Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women.
Cutaneous androgen metabolism: basic research and clinical perspectives.
Hyperandrogenemia in patients presenting with acne.
Metabolic alterations of DHEA and cholesterol sulphates in the hair of patients with acne measured by liquid chromatography-mass spectrometry.
Metformin therapy decreases hyperandrogenism and hyperinsulinemia in women with polycystic ovary syndrome.
Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups.
Predictors of severity of acne vulgaris in young adolescent girls: results of a five-year longitudinal study.
Steroid sulfatase activity in epidermis of acne-prone and non-acne-prone skin of patients with acne vulgaris.
The association of serum androsterone glucuronide with inflammatory lesions in women with adult acne.
[Androgenic evaluation of women with late-onset or persistent acne]
[Effect on skin and hormonal hyperandrogenic manifestations of an oral estroprogestin association containing ethynilestradiol 30 mg and drospirenone 3 mg]
Acquired Immunodeficiency Syndrome
Dehydroepiandrosterone sulfate (DHEAS) and testosterone: relation to HIV illness stage and progression over one year.
Addison Disease
Origin and significance of plasma androsterone glucuronide levels: a parameter of adrenal androgen secretion and hepatic 5 alpha-reductase activity.
The importance of adrenal hypoandrogenism in infertile women with low functional ovarian reserve: a case study of associated adrenal insufficiency.
Adenocarcinoma
Dehydroepiandrosterone modulates oxidative DNA damage in pancreatic cancer: A case-control study.
In situ steroid sulfatase activity in human epithelial carcinoma cells of vaginal, ovarian, and endometrial origin.
Inhibition of protein farnesyltransferase: a possible mechanism of tumor prevention by dehydroepiandrosterone sulfate.
Lifelong treatment with oral DHEA sulfate does not preserve immune function, prevent disease, or improve survival in genetically heterogeneous mice.
Steroid sulfatase expression in ovarian clear cell adenocarcinoma: immunohistochemical study.
Adenocarcinoma, Clear Cell
Steroid sulfatase expression in ovarian clear cell adenocarcinoma: immunohistochemical study.
Adenoma
A case of Cushing's syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion.
Adrenal and sex steroid hormone production by a virilizing adrenal adenoma and its diagnosis with computerized tomography.
Adrenal incidentaloma: an overview of hormonal data from the National Italian Study Group.
Asymptomatic adrenal tumours: criteria for endoscopic removal.
DHEAS and Differential Blood Counts as Indirect Signs of Glucocorticoid Excess in Adrenal Non-Producing Adenomas.
Is there an association between non-functioning adrenal adenoma and endothelial dysfunction?
Laparoscopic adrenalectomy. The importance of a flank approach in the lateral decubitus position.
Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery.
Steroid sulfation in adrenal tumors.
The value of dehydroepiandrosterone sulfate measurement in the differentiation between benign and malignant adrenal masses.
[Incidentaloma of the adrenal glands: analysis of 9 surgical cases]
Adenomyosis
Immunohistologic localization of estrone sulfatase in uterine endometrium and adenomyosis.
Adrenal Gland Neoplasms
Isolated DHEAS production by an adrenal neoplasm: Clinical, biochemical and pathologic characteristics.
The value of dehydroepiandrosterone sulfate measurement in the differentiation between benign and malignant adrenal masses.
Adrenal Hyperplasia, Congenital
Adrenarche does not occur in treated patients with congenital adrenal hyperplasia resulting from 21-hydroxylase deficiency.
Development of a method for the measurement of dehydroepiandrosterone sulphate by liquid chromatography-tandem mass spectrometry.
Disproportionate suppression of dehydroepiandrosterone sulfate (DHEAS) in treated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Hydrocortisone treatment in girls with congenital adrenal hyperplasia inhibits serum dehydroepiandrosterone sulfate and affects the GH-IGF-I system.
Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension.
Isolated dehydroepiandrosterone sulphate hypersecretion: a case report.
Premature Adrenarche and its Association with Cardiovascular Risk in Females.
Adrenal Insufficiency
Adrenal androgen and glucocorticoid dissociation in premenopausal rheumatoid arthritis: a significant correlate or precursor to onset?
Adrenal steroids in adrenomyeloneuropathy Dehydroepiandrosterone sulfate, androstenedione and 17alpha-hydroxyprogesterone.
Androgen deficiency in women with hypopituitarism.
Central adrenal insufficiency could not be confirmed by measurement of basal serum DHEAS levels in pubertal children.
Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?
Dehydroepiandrosterone: a potential therapeutic agent in the treatment and rehabilitation of the traumatically injured patient.
Dehydroepiandrosterone: a springboard hormone for female sexuality.
DHEAS deficiency during consumption of sustained-action prescribed opioids: evidence for opioid-induced inhibition of adrenal androgen production.
Effects of dehydroepiandrosterone sulphate (DHEAS) replacement on insulin action and quality of life in hypopituitary females: a double blind placebo controlled study.
Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension.
Is DHEA replacement beneficial in chronic adrenal failure?
New PCOS-like phenotype in older infertile women of likely autoimmune adrenal etiology with high AMH but low androgens.
Adrenocortical Adenoma
Benign cortisol-secreting adrenocortical adenomas produce small amounts of androgens.
Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery.
Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour.
Adrenocortical Carcinoma
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Label-free impedimetric immunosensor based on arginine-functionalized gold nanoparticles for detection of DHEAS, a biomarker of pediatric adrenocortical carcinoma.
Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery.
Adrenoleukodystrophy
Adrenal steroids in adrenomyeloneuropathy Dehydroepiandrosterone sulfate, androstenedione and 17alpha-hydroxyprogesterone.
Albinism, Ocular
An Xp22 microdeletion associated with ocular albinism and ichthyosis: approximation of breakpoints and estimation of deletion size by using cloned DNA probes and flow cytometry.
Deletion analysis maps ocular albinism proximal to the steroid sulphatase locus.
Detection of KAL-1 gene deletion with fluorescence in situ hybridization.
Linkage analysis in X-linked ocular albinism.
Alopecia
Alterations in androgen conjugate levels in women and men with alopecia.
Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension.
Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?
Steroid sulfatase in the human hair follicle concentrates in the dermal papilla.
alpha-Thalassemia
Frequent deletions of the human X chromosome distal short arm result from recombination between low copy repetitive elements.
Alzheimer Disease
Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD).
Age-related changes of the adrenal secretory pattern: possible role in pathological brain aging.
Dehydroepiandrosterone (DHEA) and its Sulphate (DHEAS) in Alzheimer's Disease.
Dehydroepiandrosterone sulfate decreases the interleukin-2-mediated overactivity of the natural killer cell compartment in senile dementia of the Alzheimer type.
Dehydroepiandrosterone sulphate (DHEAS) in the oldest old, aged 85 and over.
Rapid column-switching liquid chromatography/mass spectrometric assay for DHEA-sulfate in the plasma of patients with Alzheimer's disease.
Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multi-infarct dementia.
Amnesia
Chronic steroid sulfatase inhibition by (p-O-sulfamoyl)-N-tetradecanoyl tyramine increases dehydroepiandrosterone sulfate in whole brain.
Enhanced plasma DHEAS, brain acetylcholine and memory mediated by steroid sulfatase inhibition.
Memory enhancement mediated by the steroid sulfatase inhibitor (p-O-sulfamoyl)-N-tetradecanoyl tyramine.
Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging- and dizocilpine-induced learning impairment.
Reversal of scopolamine induced amnesia in rats by the steroid sulfatase inhibitor estrone-3-O-sulfamate.
The effect of steroid sulfatase inhibition on learning and spatial memory.
Anemia
Higher serum concentrations of DHEAS predict improved nutritional status in helminth-infected children, adolescents, and young adults in Leyte, the Philippines.
Anencephaly
Unconjugated estriol as an indication for prenatal diagnosis of steroid sulfatase deficiency by in situ hybridization.
Angina Pectoris
von Willebrand factor, tissue plasminogen activator, and dehydroepiandrosterone sulphate predict cardiovascular death in a 10 year follow up of survivors of acute myocardial infarction.
Angiomyolipoma
Laparoscopic adrenalectomy. The importance of a flank approach in the lateral decubitus position.
Anosmia
A new syndrome of anosmia, ichthyosis, hypogonadism, and various neurological manifestations with deficiency of steroid sulfatase and arylsulfatase C.
Hypogonadotrophic hypogonadism with hyposmia, X-linked ichthyosis, and renal malformation syndrome.
More on X-linked ichthyosis, steroid sulfatase deficiency, and hypogonadism and anosmia.
X-linked ichthyosis due to steroid sulfatase deficiency associated with hypogonadism and anosmia.
Anovulation
Differential response to adrenocorticotropin hormone stimulation in polycystic ovarian disease with high and low dehydroepiandrosterone sulfate levels.
Inactivating PAPSS2 mutations in a patient with premature pubarche.
The ratio of androstenedione:11 beta-hydroxyandrostenedione is an important marker of adrenal androgen excess in women.
Arteriosclerosis
Association of endogenous DHEA/DHEAS with coronary heart disease: A systematic review and meta-analysis.
Arteritis
Low serum levels of DHEAS in untreated polymyalgia rheumatica/giant cell arteritis.
Arthralgia
Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.
Arthritis
Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate and its relation to clinical variables in inflammatory arthritis.
Relation between placental growth factor-1 (PlGF-1) and vascularization, DHEAS to DHEA conversion, or aromatase expression in patients with arthritis.
Arthritis, Rheumatoid
Adrenal androgens and the immune system.
Basal levels of DHEAS as a marker for disease activity in premenopausal women with recent onset rheumatoid arthritis.
Blood dehydroepiandrosterone sulphate (DHEAS) levels in polymyalgia rheumatica/giant cell arteritis and primary fibromyalgia.
Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis.
Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.
Hypothalamic-pituitary-adrenal axis impairment in the pathogenesis of rheumatoid arthritis and polymyalgia rheumatica.
Increased DHEAS levels in patients with rheumatoid arthritis after treatment with tumor necrosis factor antagonists: evidence for improved adrenal function.
Relationship between blood and joint tissue DHEAS levels in rheumatoid arthritis and osteoarthritis.
Weak androgen levels, glucocorticoid therapy, and bone mineral density in postmenopausal women with rheumatoid arthritis.
arylsulfatase (type i) deficiency
Arylsulfatases A and B in EBV-transformed lymphoid cell lines: studies on their molecular forms in cells from patients with inborn sulfatase deficiencies. Comparative diagnostic value of enzymatic assays.
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Multiple sulfatase deficiency: catalytically inactive sulfatases are expressed from retrovirally introduced sulfatase cDNAs.
Placental sulfatase deficiency: maternal and fetal expression of steroid sulfatase deficiency and X-linked ichthyosis.
Rapid degradation of steroid sulfatase in multiple sulfatase deficiency.
Steroid sulfatase deficiency.
Steroid sulfatase sulfatase deficiency and androgen activation before and after puberty.
Synthesis and stability of steroid sulfatase in fibroblasts from multiple sulfatase deficiency.
Asthenozoospermia
[Andrologic studies in patients with X-chromosome recessive ichthyosis]
Asthma
Allergic disease as an association of steroid sulphatase deficiency.
Effects of hormone replacement therapy on endocrine and spirometric parameters in asthmatic postmenopausal women.
Independent association between insulin-like growth factor-I and dehydroepiandrosterone sulphate in women in middle adulthood.
Nebulized dehydroepiandrosterone-3-sulfate improves asthma control in the moderate-to-severe asthma results of a 6-week, randomized, double-blind, placebo-controlled study.
Atherosclerosis
Adrenal Hyperandrogenism and Polycystic Ovary Syndrome.
Berberine cooperates with adrenal androgen dehydroepiandrosterone sulfate to attenuate PDGF-induced proliferation of vascular smooth muscle cell A7r5 through Skp2 signaling pathway.
Changes in plasma DHEAS circadian rhythm in elderly men.
Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men.
Distribution of dehydroepiandrosterone sulfate and relationships between its level and serum lipid levels in a rural Japanese population.
Effects of dehydroepiandrosterone sulfate on cellular calcium responsiveness and vascular contractility.
Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: Roles of PPARalpha and NF-kappaB.
Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study.
No association between dehydroepiandrosterone sulfate and development of atherosclerosis in a prospective population study (Bruneck Study).
Relationship between dehydroepiandrosterone sulfate and serum lipid levels in Japanese men.
Serum Amyloid A, Paraoxonase-1 Activity, and Apolipoprotein Concentrations as Biomarkers of Subclinical Atherosclerosis Risk in Adrenal Incidentaloma Patients.
Serum DHEAS levels correlate with platelet cGMP in normal women.
[Replacement therapy in adrenopause. Dehydroepiandrosterone and aging]
Atrial Fibrillation
Dehydroepiandrosterone sulfate levels and risk of atrial fibrillation: The Rotterdam Study.
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Autoimmune Diseases
Administration of dehydroepiandrosterone sulfate retards onset but not progression of autoimmune disease in NZB/W mice.
Blood dehydroepiandrosterone sulphate (DHEAS) levels in pemphigoid/pemphigus and psoriasis.
Dehydroepiandrosterone sulphate serum levels in systemic sclerosis.
[The role of adrenal and gonadal hormones in the pathogenesis of autoimmune polyarthritis]
Azoospermia
[Genetic analysis of a rare case with Kallman syndrome and steroid sulfatase deficiency].
Beckwith-Wiedemann Syndrome
Functional Adrenocortical Adenoma in a Child with Beckwith-Wiedemann Syndrome.
Bone Diseases
Serum dehydroepiandrosterone sulfate, testosterone, and biochemical markers of bone turnover in elderly Thai men.
Bone Diseases, Metabolic
Dehydroepiandrosterone and Bone.
Dehydroepiandrosterone sulphate in the diagnosis of osteoporosis.
The evaluation of hormonal and psychological parameters that affect bone mineral density in postmenopausal women.
[Reduced serum dehydroepiandrosterone levels in postmenopausal osteoporosis]
Bone Resorption
Dehydroepiandrosterone: a springboard hormone for female sexuality.
Physiologic regulators of bone turnover in young women with anorexia nervosa.
Relationship between bone resorption and adrenal sex steroids and their derivatives in oophorectomized women.
Serum dehydroepiandrosterone sulfate, testosterone, and biochemical markers of bone turnover in elderly Thai men.
Brain Concussion
DHEAS repeated treatment improves cognitive and behavioral deficits after mild traumatic brain injury.
Brain Diseases
Dehydroepiandrosterone sulphate: action and mechanism in the brain.
Brain Injuries
Dehydroepiandrosterone sulfate is neuroprotective when administered either before or after injury in a focal cortical cold lesion model.
Brain Injuries, Traumatic
Astrocyte Neuroprotection and Dehydroepiandrosterone.
Brain Neoplasms
Steroid sulfatase and sulfuryl transferase activities in human brain tumors.
Breast Cyst
A simple, accurate, and sensitive assay method of dehydroepiandrosterone sulfate: application for quantitative determination in human breast cyst and duct fluids.
Accumulation of 4- and 5-ene steroid sulfates in human breast cyst fluids.
Cytokines in human breast cyst fluid.
Breast Neoplasms
2-phenylindole sulfamates: inhibitors of steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells.
A new hormonal therapy for estrogen receptor-negative breast cancer.
A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer.
A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models.
A phase I dose escalation study to determine the optimal biological dose of irosustat, an oral steroid sulfatase inhibitor, in postmenopausal women with estrogen receptor-positive breast cancer.
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy.
Anti-breast cancer potential of natural and synthetic coumarin derivatives.
Anti-tumor effect of Shu-Gan-Liang-Xue decoction in breast cancer is related to the inhibition of aromatase and steroid sulfatase expression.
Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography.
Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates.
Association between alcohol intake and serum sex hormones and peptides differs by tamoxifen use in breast cancer survivors.
Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation.
Breast cancer: from estrogen to androgen receptor.
C-3- and C-4-Substituted Bicyclic Coumarin Sulfamates as Potent Steroid Sulfatase Inhibitors.
Chromatographic analysis and decomposition product characterization of compound SR16157 (NSC 732011).
Confocal fluorescence detection expanded to UV excitation: the first continuous fluorimetric assay of human steroid sulfatase in nanoliter volume.
Constitutive expression of the steroid sulfatase gene supports the growth of MCF-7 human breast cancer cells in vitro and in vivo.
Constitutive Expression of the Steroid Sulfatase Gene Supports the Growth of MCF-7 Human Breast Cancer Cells in Vitroand in Vivo.
Conversion of dehydroepiandrosterone sulfate at physiological plasma concentration into estrogens in MCF-7 cells.
Correction to: IRIS study: a phase II study of the steroid sulfatase inhibitor Irosustat when added to an aromatase inhibitor in ER-positive breast cancer patients.
Crystal structure of human carbonic anhydrase II at 1.95 A resolution in complex with 667-coumate, a novel anti-cancer agent.
Daidzein sulfoconjugates are potent inhibitors of sterol sulfatase (EC 3.1.6.2).
Dehydroepiandrosterone concentration in breast cancer tissue is related to its plasma gradient across the mammary gland.
Dehydroepiandrosterone sulfate and breast cancer risk.
Dehydroepiandrosterone sulfate estrogenic action at its physiological plasma concentration in human breast cancer cell lines.
Design and synthesis of carbon-11-labeled dual aromatase-steroid sulfatase inhibitors as new potential PET agents for imaging of aromatase and steroid sulfatase expression in breast cancer.
Design and synthesis of silicon-containing steroid sulfatase inhibitors possessing pro-estrogen antagonistic character.
Detection of breast cancer-associated estrone sulfatase in breast cancer biopsies and cell lines using polymerase chain reaction.
Development of (p-O-sulfamoyl)-N-alkanoyl-phenylalkyl amines as non-steroidal estrone sulfatase inhibitors.
Development of a sensitive high-performance liquid chromatography method for the detection of 667 COUMATE in vivo.
Development of novel steroid sulfatase inhibitors. I. Synthesis and biological evaluation of biphenyl-4-O-sulfamates.
Development of novel steroid sulfatase inhibitors; II. TZS-8478 potently inhibits the growth of breast tumors in postmenopausal breast cancer model rats.
Development of potent non-estrogenic estrone sulfatase inhibitors.
DHEAS prevents pro-metastatic and proliferative effects of 17ß-estradiol on MCF-7 breast cancer cells.
Differential effects of progestins on breast tissue enzymes.
Differential increase of steroid sulfatase activity in XX and XY trophoblast cells from human term placenta with syncytia formation in vitro.
Direct evidence for ArO-S bond cleavage upon inactivation of Pseudomonas aeruginosa arylsulfatase by aryl sulfamates.
Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties.
Distribution of 16alpha-[18F]fluoro-estradiol-3,17beta-disulfamate in rats, tumour-bearing mice and piglets.
Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.
Effect of nomegestrol acetate on estrone-sulfatase and 17beta-hydroxysteroid dehydrogenase activities in human breast cancer cells.
Effect of tamoxifen or anastrozole on steroid sulfatase activity and serum androgen concentrations in postmenopausal women with breast cancer.
Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells.
Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer.
Estradiol inhibits the estrone sulfatase activity in normal and cancerous human breast tissues.
Estrogen sulfotransferase and steroid sulfatase in human breast carcinoma.
Estrogenicity, antiestrogenicity and estrone sulfatase inhibition of estrone-3-amine and estrone-3-thiol.
Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies.
Estrone and dehydroepiandrosterone sulfatase activities and plasma estrone sulfate levels in human breast carcinoma.
Estrone sulfatase activity and effect of antiestrogens on transformation of estrone sulfate in hormone-dependent vs. independent human breast cancer cell lines.
Estrone sulfatase versus estrone sulfotransferase in human breast cancer: potential clinical applications.
Estrone sulfate analogs as estrone sulfatase inhibitors.
Estrone sulfate and sulfatase activity in human breast cancer and endometrial cancer.
Estrone sulfate promotes human breast cancer cell replication and nuclear uptake of estradiol in MCF-7 cell cultures.
Estrone sulfate stimulates growth of nitrosomethylurea-induced breast carcinoma in vivo in the rat.
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Expression of Estrogen Sulfotransferase 1E1 and Steroid Sulfatase in Breast Cancer: A Immunohistochemical Study.
Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression.
Expression of sulfotransferases and sulfatases in human breast cancer: Impact on resveratrol metabolism.
High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer.
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity.
Immunohistochemical analysis of estrone sulfatase and aromatase in human breast cancer tissues.
Immunohistochemical analysis of steroid sulfatase in human tissues.
Impairment of the Gn?11-controlled expression of claudin-1 and MMP-9 and collective migration of human breast cancer MCF-7 cells by DHEAS.
In breast cancer subtypes steroid sulfatase (STS) is associated with less aggressive tumour characteristics.
In situ estrogen production via the estrone sulfatase pathway in breast tumors: relative importance versus the aromatase pathway.
In situ production of estrogens in human breast carcinoma.
In situ production of sex steroids in human breast carcinoma.
In vitro and in vivo models for the evaluation of new inhibitors of human steroid sulfatase, devoid of residual estrogenic activity.
In vitro effect of synthetic progestogens on estrone sulfatase activity in human breast carcinoma.
In vivo activity of 4-methylcoumarin-7-O-sulfamate, a nonsteroidal, nonestrogenic steroid sulfatase inhibitor.
In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy.
In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE.
Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate.
Inclusion of Endogenous Plasma Dehydroepiandrosterone Sulfate and Mammographic Density in Risk Prediction Models for Breast Cancer.
Inhibition of estrone sulfatase activity by estrone-3-methylthiophosphonate: a potential therapeutic agent in breast cancer.
Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens.
Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines.
Inhibition of estrone sulfatase enzyme in human placenta and human breast carcinoma.
Inhibition of estrone sulfatase in human liver microsomes by quercetin and other flavonoids.
Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate.
Inhibition of oestrone sulphatase activity by tibolone and its metabolites.
Inhibition of placental estrone sulfatase activity and MCF-7 breast cancer cell proliferation by estrone-3-amino derivatives.
Inhibition of steroid sulfatase activity and cell proliferation in ZR-75-1 and BT-474 human breast cancer cells by KW-2581 in vitro and in vivo.
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives.
Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: potential therapeutic agents in breast cancer.
Inhibition of steroid sulphatase activity via the percutaneous route: a new option for breast cancer therapy.
Intracrine mechanism of estrogen synthesis in breast cancer.
Intracrinology of breast microenvironment: hormonal status in nipple aspirate fluid and its relationship to breast cancer.
Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer.
IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer.
IRIS study: a phase II study of the steroid sulfatase inhibitor Irosustat when added to an aromatase inhibitor in ER-positive breast cancer patients.
Irosustat: a first-generation steroid sulfatase inhibitor in breast cancer.
Lack of inhibition of placental estrone sulfatase and aromatase enzymes by vitamin D3 and its analogs.
Localization of Estrone Sulfatase in Human Breast Carcinomas.
Low salivary testosterone levels in patients with breast cancer.
Measurement of oestrone sulphatase activity in white blood cells to monitor in vivo inhibition of steroid sulphatase activity by oestrone-3-O-sulphamate.
Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism.
Norelgestromin as selective estrogen enzyme modulator in human breast cancer cell lines. Effect on sulfatase activity in comparison to medroxyprogesterone acetate.
Paradoxical effect of estradiol: it can block its own bioformation in human breast cancer cells.
Phase I Study of STX 64 (667 Coumate) in Breast Cancer Patients: The First Study of a Steroid Sulfatase Inhibitor.
Postmenopausal breast cancer risk in relation to sex steroid hormones, prolactin and SHBG (Sweden).
Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up.
Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition.
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates.
Pre-diagnostic sex hormone levels and survival among breast cancer patients.
Progestins and breast cancer.
Prognostic significance of aromatase and estrone sulfatase enzymes in human breast cancer.
Quantitative analysis of aromatase, sulfatase and 17beta-HSD(1) mRNA expression in soft tissue metastases of breast cancer.
Recent advances in the development of steroid sulphatase inhibitors.
Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer.
Regulation and inhibition of steroid sulfatase activity in breast cancer.
Regulation of steroid sulphatase and oestradiol 17 beta-hydroxysteroid dehydrogenase in breast cancer.
Regulation of steroid sulphatase expression and activity in breast cancer.
Relation of serum levels of testosterone and dehydroepiandrosterone sulfate to risk of breast cancer in postmenopausal women.
Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women.
Review of estrone sulfatase and its inhibitors--an important new target against hormone dependent breast cancer.
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients.
Role, control and expression of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase activities in human breast cancer.
Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).
Sex steroid-producing enzymes in human breast cancer.
Shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells.
Shu-Gan-Liang-Xue Decoction Simultaneously Down-regulates Expressions of Aromatase and Steroid Sulfatase in Estrogen Receptor Positive Breast Cancer Cells.
Shu-Gan-Liang-Xue Decoction, a Chinese herbal formula, down-regulates the expression of steroid sulfatase genes in human breast carcinoma MCF-7 cells.
Significance of Steroid Sulfatase Expression in Human Breast Cancer.
Steroid hormones and human breast cancer. An hypothesis.
Steroid sulfatase activities in human breast tumors.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
Steroid sulfatase and estrogen sulfotransferase in normal human tissue and breast carcinoma.
Steroid sulfatase expression is an independent predictor of recurrence in human breast cancer.
Steroid sulfatase in breast carcinoma and change of serum estrogens levels after operation.
Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism.
Steroid sulfatase inhibitors: promising new therapy for breast cancer.
Steroid sulfatase inhibitors: Promising new tools for breast cancer therapy?
Steroid sulfatase inhibitors: their potential in the therapy of breast cancer.
Steroid sulfatase: a new target for the endocrine therapy of breast cancer.
Steroid sulphatase inhibitors for breast cancer therapy.
Steroidal and nonsteroidal sulfamates as potent inhibitors of steroid sulfatase.
Steroidal oxathiazine inhibitors of estrone sulfatase.
Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells.
Stimulation of MCF-7 breast cancer cell proliferation by estrone sulfate and dehydroepiandrosterone sulfate: inhibition by novel non-steroidal steroid sulfatase inhibitors.
Structure Based Design, Synthesis, And Evaluation Of Potential Inhibitors Of Steroid Sulfatase.
Structure of human estrone sulfatase suggests functional roles of membrane association.
Sulfamoyloxy-substituted 2-phenylindoles: antiestrogen-based inhibitors of the steroid sulfatase in human breast cancer cells.
Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review.
Sulfatase inhibitors: a patent review.
Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
Synthesis and biological evaluation of thiophosphate tricyclic coumarin derivatives as steroid sulfatase inhibitors.
Synthesis and sulfatase inhibitory activities of (E)- and (Z)-4-hydroxytamoxifen sulfamates.
The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women.
The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity.
The effects of 2-methoxyoestrogen sulphamates on the in vitro and in vivo proliferation of breast cancer cells.
The influence of inflammatory cytokines on estrogen production and cell proliferation in human breast cancer cells.
The role of cytokines and sulphatase inhibitors in regulating oestrogen synthesis in breast tumours.
Tissue-specific transcripts of human steroid sulfatase are under control of estrogen signaling pathways in breast carcinoma.
Understanding the biologic mechanisms responsible for breast-cancer progression during tamoxifen or fulvestrant treatment.
Uptake and concentration of steroid hormones in mammary tissues.
Using molecular docking to investigate the anti-breast cancer activity of low molecular weight compounds present on wild mushrooms.
[Actions of a 19-norprogesterone derivative on mammary gland: nomegestrol acetate]
[Genetic polymorphism and variability of steroid hormone metabolism: connection with risk of developing breast neoplasms]
[Local production of estrogen via aromatase and estrone sulfatase in breast cancer tissue]
[Steroid sulfatase inhibitor]
Campomelic Dysplasia
Prenatal diagnosis of sex differentiation disorders: the role of fetal ultrasound.
Carcinogenesis
Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53.
Detection of a novel, primate-specific ‘kill switch’ tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53
Human steroid sulfatase enhances aerobic glycolysis through induction of HIF1? and glycolytic enzymes.
Induction of steroid sulfatase expression in PC-3 human prostate cancer cells by insulin-like growth factor II.
Carcinoma
Adrenal incidentaloma: an overview of hormonal data from the National Italian Study Group.
Clinicopathological Significance of Estrogen Receptor ? and Estrogen Synthesizing/Metabolizing Enzymes in Urothelial Carcinoma of Urinary Bladder.
In situ steroid sulfatase activity in human epithelial carcinoma cells of vaginal, ovarian, and endometrial origin.
Increased serum cortisol levels are associated with high tumour grade in patients with renal cell carcinoma.
Localization of Estrone Sulfatase in Human Breast Carcinomas.
Serum dehydroepiandrosterone and dehydroepiandrosterone sulfate and risk of melanoma or squamous cell carcinoma of the skin.
Serum levels of steroid sulfatase protein in gynecologic carcinomas.
Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors.
Steroid sulfatase and estrogen sulfotransferase in human carcinomas.
Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma.
Steroid sulphatase and oestrogen sulphotransferase in human non-small-cell lung carcinoma.
Steroid-converting enzymes in human ovarian carcinomas.
Sulfamoyloxy-substituted 2-phenylindoles: antiestrogen-based inhibitors of the steroid sulfatase in human breast cancer cells.
Sulfatase Activity in Normal and Neoplastic Endometrium.
[Biochemical study on steroid sulfatase and its clinical application to the obstetrics and gynecology]
Carcinoma, Endometrioid
Sulfatase Activity in Normal and Neoplastic Endometrium.
[Biochemical study on steroid sulphatase in the endometrioid adenocarcinoma]
Carcinoma, Hepatocellular
[Molecular mechanisms of DHEA and DHEAs on apoptosis and cell cycle arrest via Akt pathway in hepatoma cell lines]
Carcinoma, Intraductal, Noninfiltrating
Intratumoral concentration of sex steroids and expression of sex steroid-producing enzymes in ductal carcinoma in situ of human breast.
Carcinoma, Non-Small-Cell Lung
Steroid sulphatase and oestrogen sulphotransferase in human non-small-cell lung carcinoma.
Carcinoma, Ovarian Epithelial
Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer.
Steroid-converting enzymes in human ovarian carcinomas.
Carcinoma, Renal Cell
Increased serum cortisol levels are associated with high tumour grade in patients with renal cell carcinoma.
Carcinoma, Squamous Cell
Serum dehydroepiandrosterone and dehydroepiandrosterone sulfate and risk of melanoma or squamous cell carcinoma of the skin.
Cardiomyopathy, Dilated
Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy.
Cardiovascular Diseases
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
Adrenal androgen dehydroepiandrosterone sulfate inhibits vascular remodeling following arterial injury.
Biotransformation of oral dehydroepiandrosterone in elderly men: significant increase in circulating estrogens.
Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study.
Cardiovascular Risk Factors and Dehydroepiandrosterone Sulfate Among Latinos in the Boston Puerto Rican Health Study.
Clinical correlates of sex steroids and gonadotropins in men over the late adulthood: the Framingham Heart Study.
Dehydroepiandrosterone sulphate (DHEAS) in the oldest old, aged 85 and over.
Dehydroepiandrosterone, dehydroepiandrosterone sulphate and cardiovascular disease.
DHEA(S): the fountain of youth.
Differential effect of carbamazepine and valproate monotherapy on plasma levels of oestrone sulphate and dehydroepiandrosterone sulphate in male epileptic patients.
Distribution of dehydroepiandrosterone sulfate and relationships between its level and serum lipid levels in a rural Japanese population.
Effect of moderate alcohol consumption on plasma dehydroepiandrosterone sulfate, testosterone, and estradiol levels in middle-aged men and postmenopausal women: a diet-controlled intervention study.
Effects of age, smoking and vitamins on plasma DHEAS levels: a cross-sectional study in men.
Effects of dehydroepiandrosterone sulfate on cellular calcium responsiveness and vascular contractility.
Increased visceral adipose tissue is associated with increased circulating insulin and decreased sex hormone binding globulin levels in massively obese adolescent girls.
Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: Roles of PPARalpha and NF-kappaB.
Measurement of serum levels of dehydroepiandrosterone sulfate: a comparison of radioimmunoassay and enzymatic analysis.
Prognostic Value of Dehydroepiandrosterone Sulfate for Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis.
Relation of dehydroepiandrosterone and dehydroepiandrosterone sulfate with cardiovascular disease risk factors in women: longitudinal results from the Massachusetts Women's Health Study.
Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study.
The epidemiology of DHEAS and cardiovascular disease.
[The relationship between serum dehydroepiandrosterone sulfate levels and factors associated with cardiovascular diseases: a cross-sectional study in Japan]
Carotid Artery Diseases
Dehydroepiandrosterone sulfate is inversely associated with sex-dependent diverse carotid atherosclerosis regardless of endothelial function.
Cataract
Relationships between hormonal status and cataract in french postmenopausal women: the POLA study.
Cerebral Infarction
The effect of dehydroepiandrosterone sulfate administration to patients with multi-infarct dementia.
Cholestasis
Transgenic Overexpression of Steroid Sulfatase Alleviates Cholestasis.
Cholestasis, Intrahepatic
Stable prolactin level after enhanced estradiol production following dehydroepiandrosterone sulfate.
Chondrodysplasia Punctata
Contiguous gene syndromes due to deletions in the distal short arm of the human X chromosome.
Deletion of the distal short arm of the X chromosome (Xp) in a patient with short stature, chondrodysplasia punctata, and X-linked ichthyosis due to steroid sulfatase deficiency.
Long-range restriction map of the terminal part of the short arm of the human X chromosome.
Prenatal diagnosis and investigation of a fetus with chondrodysplasia punctata, ichthyosis, and Kallmann syndrome due to an Xp deletion.
Role of the pseudoautosomal region in sex-chromosome pairing during male meiosis: meiotic studies in a man with a deletion of distal Xp.
X-linked dominant chondrodysplasia punctata with decreased dihydroxyacetone phosphate acyltransferase activity.
X/Y translocation in a family with X-linked ichthyosis, chondrodysplasia punctata, and mental retardation: DNA analysis reveals deletion of the steroid sulphatase gene and translocation of its Y pseudogene.
Choriocarcinoma
Estrogen production as a tumor marker in patients with gonadotropin-producing neoplasms.
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
In vitro and in vivo models for the evaluation of new inhibitors of human steroid sulfatase, devoid of residual estrogenic activity.
Role of OAT4 in Uptake of Estriol Precursor 16?-Hydroxydehydroepiandrosterone Sulfate Into Human Placental Syncytiotrophoblasts From Fetus.
Chromosome Disorders
Are low maternal estriol levels a predictor for pro-opiomelanocortin (POMC) deficiency caused by POMC mutation during pregnancy?
Coinfection
Low plasma levels of dehydroepiandrosterone sulphate in HIV-positive patients coinfected with hepatitis C virus.
Colitis, Ulcerative
Association of dehydroepiandrosterone sulfate and testosterone deficiency with bone turnover in men with inflammatory bowel disease.
Association of humoral markers of inflammation and dehydroepiandrosterone sulfate or cortisol serum levels in patients with chronic inflammatory bowel disease.
Blood and tissue dehydroepiandrosterone sulphate levels and their relationship to chronic inflammatory bowel disease.
Colonic Neoplasms
Serum dehydroepiandrosterone and dehydroepiandrosterone sulfate and the subsequent risk of developing colon cancer.
[Molecular mechanisms of DHEA and DHEAs on apoptosis and cell cycle arrest via Akt pathway in hepatoma cell lines]
Colorectal Neoplasms
Estrogen Activation by Steroid Sulfatase increases Colorectal Cancer proliferation via GPER.
Estrone Sulfate Transport and Steroid Sulfatase Activity in Colorectal Cancer: Implications for Hormone Replacement Therapy.
Reduced expression of steroid sulfatase in primary colorectal cancer.
Coma
Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy.
Corneal Dystrophies, Hereditary
Pre-Descemet corneal dystrophy and X-linked ichthyosis associated with deletion of Xp22.31 containing the STS gene.
Corneal Opacity
Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis.
Clinical pathologic correlation of superficial corneal opacities in X-linked ichthyosis.
X-linked recessive ichthyosis.
Coronary Artery Disease
Dehydroepiandrosterone and coronary atherosclerosis.
Dehydroepiandrosterone sulfate induces acute vasodilation of porcine coronary arteries in vitro and in vivo.
Plasma levels of estradiol, testosterone, and DHEAS do not predict risk of coronary artery disease in men.
Serum DHEAS levels correlate with platelet cGMP in normal women.
[Dehydroepiandrosterone (DHEA)--slows down the aging process?]
Coronary Disease
Are low dehydroepiandrosterone sulphate levels predictive for cardiovascular diseases? A review of prospective and retrospective studies.
Association of endogenous DHEA/DHEAS with coronary heart disease: A systematic review and meta-analysis.
Dehydroepiandrosterone sulfate and the risk of myocardial infarction in US male physicians: a prospective study.
Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women. The Rancho Bernardo Study.
Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men.
Dehydroepiandrosterone, dehydroepiandrosterone sulphate and cardiovascular disease.
[Dehydroepiandrosterone therapy in men with angiographically verified coronary heart disease: the effects on plasminogen activator inhibitor-1 (PAI-1), tissue plasminogen activator (tPA) and fibrinogen plasma concentrations.]
COVID-19
Does dehydroepiandrosterone sulfate have a role in COVID-19 prognosis and treatment?
Crohn Disease
Association of humoral markers of inflammation and dehydroepiandrosterone sulfate or cortisol serum levels in patients with chronic inflammatory bowel disease.
Blood and tissue dehydroepiandrosterone sulphate levels and their relationship to chronic inflammatory bowel disease.
Cryptorchidism
Clinical spectrum of steroid sulfatase deficiency: X-linked recessive ichthyosis, birth complications and cryptorchidism.
End-stage renal failure in a child with X-linked ichthyosis.
Nonsyndromic types of ichthyoses - an update.
X-linked recessive ichthyosis.
[Steroid sulfatase and placental deficiency. Current data as instigators of new research]
Cushing Syndrome
A case of Cushing's syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion.
A case of pheochromocytoma with negative MIBG scintigraphy, PET-CT and genetic tests (VHL included) and a rare case of post-operative erectile dysfunction.
Body composition in pituitary, adrenal and iatrogenic Cushing's syndrome and effects of DHEAS levels.
DHEAS for the prediction of subclinical Cushing's syndrome: perplexing or advantageous?
Effects of sex steroids on bone in women with subclinical or overt endogenous hypercortisolism.
Isolated dehydroepiandrosterone sulphate hypersecretion: a case report.
Laparoscopic adrenalectomy. The importance of a flank approach in the lateral decubitus position.
Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas.
Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour.
THE EVALUATION OF INCIDENTALLY DISCOVERED ADRENAL MASSES.
Cysts
Accumulation of 4- and 5-ene steroid sulfates in human breast cyst fluids.
Laparoscopic adrenalectomy. The importance of a flank approach in the lateral decubitus position.
Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery.
Deficiency Diseases
Steroid sulphatase deficiency disease.
Dementia
A prospective study of dehydroepiandrosterone sulfate and cognitive function in an older population: the Rancho Bernardo Study.
Cognitive and affective disorders in the elderly: a neuroendocrine study.
Dehydroepiandrosterone (DHEA) supplementation for cognition and well-being.
Dehydroepiandrosterone (DHEA) supplementation for cognitive function .
Dehydroepiandrosterone sulfate, diseases and mortality in a general aged population.
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Growth factors decrease in subjects with mild to moderate Alzheimer's disease (AD): potential correction with dehydroepiandrosterone-sulphate (DHEAS).
Hippocampal perfusion and pituitary-adrenal axis in Alzheimer's disease.
Neurosteroids: Cerebrospinal fluid levels for Alzheimer's disease and vascular dementia diagnostics.
Pineal and pituitary-adrenocortical function in physiological aging and in senile dementia.
Plasma testosterone, dehydroepiandrosterone sulfate, and cortisol in female patients with Huntington's disease.
Relationships of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mortality: a French community-based study.
Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multi-infarct dementia.
WITHDRAWN: Dehydroepiandrosterone (DHEA) supplementation for cognitive function.
Dementia, Vascular
Neurosteroids: Cerebrospinal fluid levels for Alzheimer's disease and vascular dementia diagnostics.
Dermatitis, Atopic
Steroid concentrations in atopic dermatitis patients: Reduced plasma DHEAS and increased cortisone levels.
Dermatitis, Contact
Relationship between humoral immunoaugmenting properties of DHEAS and IgD-receptor expression in young and aged mice.
Diabetes Mellitus
Association of decrease in serum dehydroepiandrosterone sulfate levels with the progression to type 2 diabetes in men of a Japanese population: the Funagata Study.
Dehydroepiandrosterone sulfate, diseases and mortality in a general aged population.
DHEA, DHEAS and prolactin correlate with glucose control parameters in women of fertile age with type-1 diabetes mellitus.
Independent association between insulin-like growth factor-I and dehydroepiandrosterone sulphate in women in middle adulthood.
[A relationship between dehydroepiandrosterone sulphate and insulin resistance in obese men and women]
[Low levels of dehydroepiandrosterone sulfate in adult males with insulin-dependent diabetes mellitus]
Diabetes Mellitus, Type 1
Dehydroepiandrosterone sulfate does not prevent spontaneous and iodine-induced lymphocytic thyroiditis and diabetes mellitus in the BB/Wor rat.
[Low levels of dehydroepiandrosterone sulfate in adult males with insulin-dependent diabetes mellitus]
Diabetes Mellitus, Type 2
Association of decrease in serum dehydroepiandrosterone sulfate levels with the progression to type 2 diabetes in men of a Japanese population: the Funagata Study.
Dietary composition affects regional body fat distribution and levels of dehydroepiandrosterone sulphate (DHEAS) in post-menopausal women with Type 2 diabetes.
Hepatic Overexpression of Steroid Sulfatase Ameliorates Mouse Models of Obesity and Type 2 Diabetes through Sex-specific Mechanisms.
Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study.
Serum Dehydroepiandrosterone Sulfate and Risk for Type 2 Diabetes in Older Men and Women: The Pro.V.A Study.
[A relationship between dehydroepiandrosterone sulphate and insulin resistance in obese men and women]
Disorder of Sex Development, 46,XY
Prenatal diagnosis of sex differentiation disorders: the role of fetal ultrasound.
Down Syndrome
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Placental synthesis of oestriol in Down's syndrome pregnancies.
Dwarfism, Pituitary
Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males.
Dyslipidemias
Dehydroepiandrosterone Sulfate (DHEAS) Levels in Polycystic Ovarian Syndrome (PCOS).
Dysostoses
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Dyspnea
Relationships of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mortality: a French community-based study.
Encephalitis
Neuroprotective Effects of Dehydroepiandrosterone Sulfate Through Inhibiting Expression of Matrix Metalloproteinase-9 from Bradykinin-Challenged Astroglia.
Endometrial Hyperplasia
Estrone sulfatase activity in normal and abnormal endometrium.
In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia.
Endometrial Neoplasms
Circulating levels of sex steroid hormones and risk of endometrial cancer in postmenopausal women.
Estrogen formation in endometrial and cervix cancer cell lines: Involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12).
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma.
Steroid sulfatase: A pivotal player in estrogen synthesis and metabolism.
The Role of Steroid Sulfatase as a Prognostic Factor in Patients with Endometrial Cancer.
The sulfatase pathway as estrogen supply in endometrial cancer.
The use of steroid sulfatase inhibitors as a novel therapeutic strategy against hormone-dependent endometrial cancer.
[Biochemical study on steroid sulfatase and its clinical application to the obstetrics and gynecology]
[Prognostic significance of assay of sex hormones, their receptors and enzymes involved in estrogen synthesis and metabolism in endometrial carcinoma]
Endometriosis
Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase expression in endometriosis tissue and stromal cells.
Estrogen metabolizing enzymes in endometrium and endometriosis.
Gonadotropin-releasing hormone agonist inhibits estrone sulfatase expression of cystic endometriosis in the ovary.
Inhibition of steroid sulfatase decreases endometriosis in an in vivo murine model.
Inhibition of steroid sulphatase activity in endometriotic implants by 667 COUMATE: a potential new therapy.
Oncological markers CA-125, CA 19-9 and endometriosis.
Strong expression of steroid sulfatase in human cumulus cells in patients with endometriosis.
Sulfatase inhibitors: a patent review.
SULFATION PATHWAYS: Contribution of intracrine oestrogens to the aetiology of endometriosis.
Synergistic Effects of E2MATE and Norethindrone Acetate on Steroid Sulfatase Inhibition: A Randomized Phase I Proof-of-Principle Clinical Study in Women of Reproductive Age.
Epidermolysis Bullosa Simplex
Recurrent bilateral corneal erosions due to an association of epidermolysis bullosa simplex Köbner and X-linked ichthyosis with steroid sulfatase deficiency.
Epilepsy
Effects of valproate and carbamazepine monotherapy on neuroactive steroids, their precursors and metabolites in adult men with epilepsy.
Effects of valproate on reproductive endocrine function in male patients with epilepsy: A systematic review and meta-analysis.
Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy.
Seizure frequency and cortisol and dehydroepiandrosterone sulfate (DHEAS) levels in women with epilepsy receiving antiepileptic drug treatment.
Epileptic Syndromes
Seizure frequency and cortisol and dehydroepiandrosterone sulfate (DHEAS) levels in women with epilepsy receiving antiepileptic drug treatment.
Erectile Dysfunction
Are dehydroepiandrosterone sulphate and lipids associated with erectile dysfunction?
The Relationships of Dehydroepiandrosterone Sulfate, Erectile Function and General Psychological Health.
Erythema
Lipids in the pathogenesis of ichthyosis: topical cholesterol sulfate-induced scaling in hairless mice.
Essential Hypertension
A close association between insulin resistance and dehydroepiandrosterone sulfate in subjects with essential hypertension.
Clinical implications of genetic and acquired defects in catecholamine synthesis and metabolism.
Relationship between blood pressure variability and serum dehydroepiandrosterone sulfate levels.
Euthyroid Sick Syndromes
Altered adrenal and thyroid function in children with insulin-dependent diabetes mellitus.
Fatigue Syndrome, Chronic
Levels of DHEA and DHEAS and responses to CRH stimulation and hydrocortisone treatment in chronic fatigue syndrome.
Fatty Liver
Dehydroepiandrosterone sulfate and cytochrome P450 inducers alleviate fatty liver in male rats fed an orotic acid-supplemented diet.
The association of dehydroepiandrosterone, obesity, waist-hip ratio and insulin resistance with fatty liver in postmenopausal women--a hyperinsulinemic euglycemic insulin clamp study.
Fetal Death
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Maternal serum unconjugated estriol as a predictor for Smith-Lemli-Opitz syndrome and other fetal conditions.
Fetal Growth Retardation
Serum dehydroepiandrosterone sulfate levels and pubarche in short children born small for gestational age before and during growth hormone treatment.
Fibromyalgia
During a corticotropin-releasing hormone test in healthy subjects, administration of a beta-adrenergic antagonist induced secretion of cortisol and dehydroepiandrosterone sulfate and inhibited secretion of ACTH.
Follicular Cyst
Isosexual pseudoprecocious puberty in a 2(1/2)-year-old girl presenting with intense skin pigmentation.
Fragile X Syndrome
A family with fragile X syndrome, Duchenne muscular dystrophy and ichthyosis transmitted by an asymptomatic carrier.
Genetic Diseases, Inborn
Male-pattern baldness in men with X-linked recessive ichthyosis.
Male-pattern baldness is common in men with X-linked recessive ichthyosis.
Mutations in X-linked ichthyosis disrupt the active site structure of estrone/DHEA sulfatase.
Placental steroid sulphatase deficiency: an approach to antenatal care and delivery.
Steroid sulfatase deficiency.
Xp22.3 interstitial deletion: A recognizable chromosomal abnormality encompassing VCX3A and STS genes in a patient with X-linked ichthyosis and mental retardation.
[Steroid sulfatase and placental deficiency. Current data as instigators of new research]
Giant Cell Arteritis
Low serum levels of DHEAS in untreated polymyalgia rheumatica/giant cell arteritis.
Glioma
Drug-induced differentiation of a rat glioma in vitro: II. the expression of S-100, a glial specific protein and steroid sulfatase.
Glucose Intolerance
Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study.
Goiter
Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension.
Guillain-Barre Syndrome
Neurosteroids in cerebrospinal fluid in neurologic disorders.
Gynecomastia
Leptin levels in boys with pubertal gynecomastia.
Heart Diseases
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
Dehydroepiandrosterone (DHEA) levels in patients with prostatic cancer, heart diseases and under surgery stress.
Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women. The Rancho Bernardo Study.
Low dehydroepiandrosterone sulfate and heart disease in middle-aged men: cross-sectional results from the Massachusetts Male Aging Study.
Heart Failure
Dehydroepiandrosterone levels vary according as heart failure condition in patients with idiopathic dilated cardiomyopathy.
During a corticotropin-releasing hormone test in healthy subjects, administration of a beta-adrenergic antagonist induced secretion of cortisol and dehydroepiandrosterone sulfate and inhibited secretion of ACTH.
The plasma levels of dehydroepiandrosterone sulfate are decreased in patients with chronic heart failure in proportion to the severity.
[A comparative survey of sex hormones levels between elderly men with chronic heart failure and normal elderly subjects]
Hepatic Encephalopathy
Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy.
Hepatitis B
Role of serum dehydroepiandrosterone sulfate level on the clearance of chronic hepatitis B virus infection.
The effect of endogenous dehydroepiandrosterone sulphate on antibody response to hepatitis B vaccine in neonates.
Hepatoblastoma
[Molecular mechanisms of DHEA and DHEAs on apoptosis and cell cycle arrest via Akt pathway in hepatoma cell lines]
Hepatomegaly
Effects of acute administration of dehydroepiandrosterone-sulfate on adipose tissue mass and cellularity in male rats.
Herpes Zoster
Adrenal androgens and aging.
Adrenarche and the evolution of human life history.
DHEAS and Human Development: An Evolutionary Perspective.
Dissecting human adrenal androgen production.
McCune-Albright Syndrome with Male Premature Pubarche of Unusual Origin.
Neurosteroid transport by the organic solute transporter OST?-OST?.
Novel presence of luteinizing hormone/chorionic gonadotropin receptors in human adrenal glands.
Premature adrenarche: novel lessons from early onset androgen excess.
Selective increases in adrenal steroidogenic capacity during acute respiratory disease in infants.
Hirsutism
Androgen dependence of hirsutism, acne, and alopecia in women: retrospective analysis of 228 patients investigated for hyperandrogenism.
Association between biochemical hyperandrogenism parameters and Ferriman-Gallwey score in patients with polycystic ovary syndrome: A systematic review and meta-regression analysis.
CAG repeat polymorphism in androgen receptor gene is not directly associated with polycystic ovary syndrome but influences serum testosterone levels.
Clinical efficacy of lower dose flutamide 125 mg/day in the treatment of hirsutism.
Clomiphene citrate and dexamethazone in treatment of clomiphene citrate-resistant polycystic ovary syndrome: a prospective placebo-controlled study.
Correlation of Cutaneous Manifestations with Body Mass Index, Blood Glucose, and Hormonal Levels in Patients with Polycystic Ovarian Disease.
Cushing's syndrome: new variants and association with empty sella syndrome.
Effects of Metformin Treatment on Soluble Leptin Receptor Levels in Women with Polycystic Ovary Syndrome.
Finasteride in the treatment of hirsutism: new therapeutic perspectives.
Finasteride treatment for one year in 35 hirsute patients.
First Report of Retroperitoneal Mucinous Cystadenoma in a Patient with Hirsutism.
Idiopathic hirsutism: an uncommon cause of hirsutism in Alabama.
Impact of adrenal versus ovarian androgen ratio on signs and symptoms of polycystic ovarian syndrome.
Marked hyperandrogenicity in a 60-year-old woman.
Metformin therapy decreases hyperandrogenism and hyperinsulinemia in women with polycystic ovary syndrome.
Modified Ferriman-Gallwey hirsutism score and androgen levels in Turkish women.
Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups.
Predictive value of glucose-insulin ratio in PCOS and profile of women who will benefit from metformin therapy: obese, lean, hyper or normoinsulinemic?
Screening for Androgen Excess in Women: Accuracy of Self-Reported Excess Body Hair Growth and Menstrual Dysfunction.
Serum levels of DHEAS in gynecologic endocrinopathy and infertility.
Sibutramine has a positive effect on clinical and metabolic parameters in obese patients with polycystic ovary syndrome.
Steroid sulfatase in the human hair follicle concentrates in the dermal papilla.
The effect of dehydroepiandrosterone sulfate prolactin and testosterone hormones in female fertility and hirsutism.
The effect of probiotics, prebiotics, and synbiotics on hormonal and inflammatory indices in women with polycystic ovary syndrome: a systematic review and meta-analysis.
The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism.
The Hirsute Woman: Challenges in the Evaluation and Management.
The role and importance of auxiliary tests in differential diagnosis in patients with mildly high basal 17-oh-progesterone levels in the evaluation of hirsutism.
Total testosterone and DHEAS levels as predictors of androgen-secreting neoplasms: a populational study.
Treatment of hyperandrogenism and hyperinsulinemia in PCOS patients with essential aminoacids. A pilot clinical study.
[Hirsutism and hypertrichosis in adults: investigations and treatment]
HIV Infections
Blood cortisol and dehydroepiandrosterone sulphate (DHEAS) levels and CD4 T cell counts in HIV infection.
HIV-1 clade C infection and progressive disruption in the relationship between cortisol, DHEAS and CD4 cell numbers: a two-year follow-up study.
Relationship between sex steroid hormone levels and CD4 lymphocytes in HIV infected men.
Usefulness of alternate prognostic serum and plasma markers for antiretroviral therapy for human immunodeficiency virus type 1 infection.
Hydrocephalus
Second-trimester maternal serum screening using alpha-fetoprotein, human chorionic gonadotrophin, and unconjugated oestriol: experience of a regional programme.
Hyperaldosteronism
Asymptomatic adrenal tumours: criteria for endoscopic removal.
Laparoscopic adrenalectomy. The importance of a flank approach in the lateral decubitus position.
Hyperalgesia
Intrathecal injection of the neurosteroid, DHEAS, produces mechanical allodynia in mice: involvement of spinal sigma-1 and GABA(A) receptors.
Neurosteroid dehydroepiandrosterone sulphate enhances pain transmission in rat spinal cord dorsal horn.
Peripheral neurosteroids enhance P2X receptor-induced mechanical allodynia via a sigma-1 receptor-mediated mechanism.
Hyperandrogenism
Adrenal androgen excess and body mass index in polycystic ovary syndrome.
Association of Luteinizing hormone and LH receptor gene polymorphism with susceptibility of Polycystic ovary syndrome.
Clinical features and hormonal characteristics in a case of ovarian arrhenoblastoma.
Clinical, endocrine, and metabolic effects of acarbose, a alpha-glucosidase inhibitor, in overweight and nonoverweight patients with polycystic ovarian syndrome.
Comparison of Two Statistical Methods to Determine Normal Range of Androgen Hormones: K-Means Cluster Analysis and Receiver Operating Characteristic Curve.
Differential response to adrenocorticotropin hormone stimulation in polycystic ovarian disease with high and low dehydroepiandrosterone sulfate levels.
Diurnal rhythm and effects of oral contraceptives on serum dehydroepiandrosterone sulfate (DHEAS) are related to alterations in serum albumin rather than to changes in adrenocortical steroid secretion.
High DHEAS Level in Girls Is Associated with Earlier Pubertal Maturation and Mild Increase in Androgens throughout Puberty without Affecting Postmenarche Ovarian Morphology.
Hirsutism in women. Effective therapy that is safe for long-term use.
Impact of rs2414096 polymorphism of CYP19 gene on susceptibility of polycystic ovary syndrome and hyperandrogenism in Kashmiri women.
Influence of adrenal hyperandrogenism on the clinical and metabolic phenotype of women with polycystic ovary syndrome.
Investigation of hypothalamo-pituitary-gonadal axis and glucose intolerance among the first-degree female relatives of women with polycystic ovary syndrome.
Lack of an ovarian function influence on the increased adrenal androgen secretion present in women with functional ovarian hyperandrogenism.
Leydig cell hyperplasia and Leydig cell tumour in postmenopausal women: report of two cases.
Low DHEAS Concentration in a Girl Presenting with Short Stature and Premature Pubarche: A Novel PAPSS2 Gene Mutation.
Modified Ferriman-Gallwey hirsutism score and androgen levels in Turkish women.
Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study.
Ovarian suppression with triptorelin and adrenal stimulation with adrenocorticotropin in functional hyperadrogenism: role of adrenal and ovarian cytochrome P450c17 alpha.
Prevalence and metabolic characteristics of adrenal androgen excess in hyperandrogenic women with different phenotypes.
[Effect on skin and hormonal hyperandrogenic manifestations of an oral estroprogestin association containing ethynilestradiol 30 mg and drospirenone 3 mg]
Hypercholesterolemia
Increased cholesterol sulfate in plasma and red blood cell membranes of steroid sulfatase deficient patients.
The epidemiology of DHEAS and cardiovascular disease.
Hyperglycemia
Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.
Hypothalamic-pituitary-adrenal-axis dysregulation and double product increases potentiate ischemic heart disease risk in a Black male cohort: the SABPA study.
Impact of glycemic variations on the regulation of androgen metabolism in obese women with polycystic ovary syndrome.
No acute effect of physiological insulin increase on dehydroepiandrosterone sulfate in women with obesity and/or polycystic ovarian disease.
Hyperinsulinism
Acute hyperinsulinemia, androgen homeostasis and insulin sensitivity in healthy man.
Dehydroepiandrosterone sulfate and insulin resistance in patients with polycystic ovary syndrome.
Effect of acute physiological elevations of insulin on circulating androgen levels in nonobese women.
Growth and pubertal development following pediatric heart transplantation: a 15-year experience at Ste-Justine Hospital.
Hyperinsulinemia is associated with menstrual irregularity and altered serum androgens in Pima Indian women.
Lack of effect of insulin or insulin-like growth factor I on the steroid sulfatase activity of human placental cytotrophoblasts.
No acute effect of physiological insulin increase on dehydroepiandrosterone sulfate in women with obesity and/or polycystic ovarian disease.
Prevention of high fructose-induced metabolic syndrome in male wistar rats by aqueous extract of Tamarindus indica seed.
Role of dehydroepiandrosterone sulfate levels on body composition after laparoscopic adjustable gastric banding in pre-menopausal morbidly obese women.
Serum soluble leptin receptor levels and free leptin index in women with polycystic ovary syndrome: relationship to insulin resistance and androgens.
Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome.
Vanadyl sulfate ameliorates insulin resistance and restores plasma dehydroepiandrosterone-sulfate levels in fructose-fed, insulin-resistant rats.
[Androgen response in women with polycystic ovary syndrome and hyperinsulinemia during stimulation with corticotrophin and inhibition with dexamethasone]
[Hirsutism and hypertrichosis in adults: investigations and treatment]
[Low levels of dehydroepiandrosterone sulfate in adult males with insulin-dependent diabetes mellitus]
[Polycystic ovary and diazoxide. In vivo study]
Hyperlipoproteinemia Type II
Gonadal steroids, gonadotropins and DHEAS in young adults with familial hypercholesterolemia who had initiated statin therapy in childhood.
Hyperprolactinemia
Cushing's syndrome: new variants and association with empty sella syndrome.
Effect of hyperprolactinemia on the androgen response to an oral glucose load.
Hypersensitivity
Neurosteroid dehydroepiandrosterone sulphate enhances pain transmission in rat spinal cord dorsal horn.
Hypertension
Activation of 11 beta-hydroxysteroid dehydrogenase by dehydroepiandrosterone sulphate as an anti-hypertensive agent in spontaneously hypertensive rats.
Analysis of relationships between the concentrations of total testosterone and dehydroepiandrosterone sulfate and the occurrence of selected metabolic disorders in aging men.
Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study.
Cortisol, dehydroepiandrosterone sulphate, their ratio and hypertension: evidence of associations in male veterans from the Vietnam Experience Study.
Dehydroepiandrosterone sulfate in a long-term care aged population.
Hypothalamic-pituitary-adrenal-axis dysregulation and double product increases potentiate ischemic heart disease risk in a Black male cohort: the SABPA study.
Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension.
Left ventricular mass index and ventricular septum thickness are associated with serum dehydroepiandrosterone-sulphate levels in hypertensive women.
Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: prospective results from the Massachusetts Male Aging Study.
Low dehydroepiandrosterone sulfate and heart disease in middle-aged men: cross-sectional results from the Massachusetts Male Aging Study.
Relation between dehydroepiandrosterone sulfate and blood pressure levels in a population-based sample.
Relationship between blood pressure variability and serum dehydroepiandrosterone sulfate levels.
Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study.
Steroid sulfatase inhibitor alters blood pressure and steroid profiles in hypertensive rats.
The epidemiology of DHEAS and cardiovascular disease.
von Willebrand factor, tissue plasminogen activator, and dehydroepiandrosterone sulphate predict cardiovascular death in a 10 year follow up of survivors of acute myocardial infarction.
Hyperthyroidism
Decreased serum IGF-I and dehydroepiandrosterone sulphate may be risk factors for the development of reduced bone mass in postmenopausal women with endogenous subclinical hyperthyroidism.
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Hypoglycemia
Cortisol hyporesponsiveness to the low dose ACTH test is a frequent finding in a pediatric population with type 1 diabetes mellitus.
Hypoglycemia and Glucocorticoid-free Immunosuppression are Related With Low Dehydroepiandrosterone Sulfate Level.
Impact of glycemic variations on the regulation of androgen metabolism in obese women with polycystic ovary syndrome.
Hypogonadism
A new syndrome of anosmia, ichthyosis, hypogonadism, and various neurological manifestations with deficiency of steroid sulfatase and arylsulfatase C.
Androgen deficiency in women with hypopituitarism.
Hypogonadotrophic hypogonadism with hyposmia, X-linked ichthyosis, and renal malformation syndrome.
Ichthyosis vulgaris with hypogenitalism and hypogonadism: evidence for different genotypes by lipoprotein electrophoresis and steroid sulfatase testing.
Inhibin B, AMH, but not INSL3, IGF1 or DHEAS support differentiation between constitutional delay of growth and puberty and hypogonadotropic hypogonadism.
More on X-linked ichthyosis, steroid sulfatase deficiency, and hypogonadism and anosmia.
Persistent amenorrhea and decreased DHEAS to cortisol ratio after recovery from anorexia nervosa.
Primary hypogonadism in females with infantile onset spinocerebellar ataxia.
Steroid sulphatase deficiency and hypogonadism.
X-linked ichthyosis due to steroid sulfatase deficiency associated with hypogonadism and anosmia.
X-linked ichthyosis with hypogonadism: not always Kallmann's syndrome.
X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome.
[Hormone therapy in the aging male. Estrogen, DHEA, melatonin, somatotropin]
[Steroid sulfatase and placental deficiency. Current data as instigators of new research]
Hypophosphatemia
Mapping of the glycine receptor alpha 2-subunit gene and the GABAA alpha 3-subunit gene on the mouse X chromosome.
Hypothyroidism
Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Plasma dehydroepiandrosterone sulphate in hypothyroid premenopausal women.
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Ichthyosis
A clinical and genetic study of X-linked recessive ichthyosis and contiguous gene defects.
A familial X/Y translocation in a boy with ichthyosis, hypogonadism and mental retardation.
A family with fragile X syndrome, Duchenne muscular dystrophy and ichthyosis transmitted by an asymptomatic carrier.
A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins.
A model of corrective gene transfer in X-linked ichthyosis.
A new method for the determination of steroid sulphatase activity in leukocytes in X-linked recessive ichthyosis.
A new syndrome of anosmia, ichthyosis, hypogonadism, and various neurological manifestations with deficiency of steroid sulfatase and arylsulfatase C.
A novel point mutation in the steroid sulfatase gene in X-linked ichthyosis.
A study of the steroid sulfatase gene in families with X-linked ichthyosis using polymerase chain reaction.
Abnormal androgen and oestrogen metabolism in men with steroid sulphatase deficiency and recessive X-linked ichthyosis.
Absence of male-pattern baldness in men with X-linked recessive ichthyosis? A hypothesis to be challenged.
Absence of testicular steroid sulphatase activity in a boy with recessive X-linked ichthyosis and testicular maldescent.
An update on molecular aspects of the non-syndromic ichthyoses.
An Xp22 microdeletion associated with ocular albinism and ichthyosis: approximation of breakpoints and estimation of deletion size by using cloned DNA probes and flow cytometry.
Analysis of the VCX3A, VCX2 and VCX3B genes shows that VCX3A gene deletion is not sufficient to result in mental retardation in X-linked ichthyosis.
Arylsulfatase C activities in skin preparations of X-linked and autosomal dominant ichthyosis.
Assignment by deletion mapping of the steroid sulfatase X-linked ichthyosis locus to Xp223.
Atypical X-linked ichthyosis in a patient with a large deletion involving the steroid sulfatase (STS) gene.
Autosomal dominant and X-linked ichthyosis in the same family. Biochemical analysis of steroid sulfatase activity.
Banding pattern on polarized hair microscopic examination and unilateral polymicrogyria in a patient with steroid sulfatase deficiency.
Basis for abnormal desquamation and permeability barrier dysfunction in RXLI.
Behavioural and psychiatric phenotypes in female carriers of genetic mutations associated with X-linked ichthyosis.
Behavioural and Psychiatric Phenotypes in Men and Boys with X-Linked Ichthyosis: Evidence from a Worldwide Online Survey.
Burn injury and wound healing in X-linked ichthyosis.
Carrier identification by FISH analysis in isolated cases of X-linked ichthyosis.
Carrier identification in steroid sulphatase deficiency and recessive X-linked ichthyosis.
Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis.
Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein.
Cholesterol sulfotransferase of newborn mouse epidermis.
Cholesterol sulphate in the microsomal sulphatase deficient placenta.
Clinical features and genetic analysis of two Chinese families with X-linked ichthyosis.
Clinical pathologic correlation of superficial corneal opacities in X-linked ichthyosis.
Clinical spectrum of steroid sulfatase deficiency: X-linked recessive ichthyosis, birth complications and cryptorchidism.
Cloning of a cDNA for steroid sulfatase: frequent occurrence of gene deletions in patients with recessive X chromosome-linked ichthyosis.
CO-OCCURRENCE OF PRIMARY MICROCEPHALY CAUSED BY A NOVEL HOMOZYGOUS ASPM MUTATION ALONG WITH X-LINKED ICHTHYOSIS IN THE SAME PATIENT.
Commercial assay for steroid sulphatase activity in X-linked ichthyosis.
Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis.
Deficiency of arylsulfatase C in cultured skin fibroblasts of X-linked ichthyosis.
Deletion analysis maps ocular albinism proximal to the steroid sulphatase locus.
Deletion of a DNA sequence in eight of nine families with X-linked ichthyosis (steroid sulphatase deficiency).
Deletion of distal promoter of VCXA in a patient with X-linked ichthyosis associated with borderline mental retardation.
Deletion of exons 1-5 of the STS gene causing X-linked ichthyosis.
Deletion of the distal short arm of the X chromosome (Xp) in a patient with short stature, chondrodysplasia punctata, and X-linked ichthyosis due to steroid sulfatase deficiency.
Deletion pattern of the steroid sulphatase gene in Japanese patients with X-linked ichthyosis.
Deletion pattern of the STS gene in X-linked ichthyosis in a Mexican population.
Deletion patterns of the STS gene and flanking sequences in Israeli X-linked ichthyosis patients and carriers: analysis by polymerase chain reaction and fluorescence in situ hybridization techniques.
Deletions of the steroid sulphatase gene in "classical" X-linked ichthyosis and in X-linked ichthyosis associated with Kallmann syndrome.
Detection of carriers for X-linked ichthyosis by Southern blot analysis and identification of one family with a de novo mutation.
Detection of heterozygotes of X-linked ichthyosis by measuring steroid sulphatase activity of lymphocytes. Mode of inheritance in three families.
Diagnosis of a deletion of steroid sulfatase by polymerase chain reaction and high-performance liquid chromatography.
Enzymatic basis of typical X-linked icthyosis.
Evidence of the high prevalence of neurological disorders in nonsyndromic X-linked recessive ichthyosis: a retrospective case series.
Exacerbation of ichthyosis vulgaris phenotype by co-inheritance of STS and FLG mutations in a Chinese family with ichthyosis: a case report.
Exacerbation of X-linked ichthyosis phenotype in a female by inheritance of filaggrin and steroid sulfatase mutations.
Failure of steroid sulfatase to desulfate vitamin D3 sulfate.
Familial X-linked ichthyosis, steroid sulfatase deficiency, mental retardation, and nullisomy for Xp223-pter.
Fine mapping of the distal short arm of the human X chromosome using X/Y translocations.
Further evidence for the assignment of the steroid sulfatase X-linked ichthyosis locus to the telomer of Xp.
Genetic complementation of steroid sulphatase after somatic cell hybridization of X-linked ichthyosis and multiple sulphatase deficiency.
Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase.
Genetic skin diseases.
Hair root analysis in X-linked ichthyosis.
High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency.
Hypogonadotrophic hypogonadism with hyposmia, X-linked ichthyosis, and renal malformation syndrome.
Ichthyosis of steroid sulphatase deficiency. Clinical study of 76 cases.
Ichthyosis vulgaris with hypogenitalism and hypogonadism: evidence for different genotypes by lipoprotein electrophoresis and steroid sulfatase testing.
Ichthyosis. Reliability of clinical signs in the differentiation between autosomal dominant and sex-linked forms.
Ichthyosis: etiology, diagnosis, and management.
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Identification of point mutations in the steroid sulfatase gene of three patients with X-linked ichthyosis.
In vivo confocal microscopy of pre-Descemet corneal dystrophy associated with X-linked ichthyosis: a case report.
Increased cholesterol sulfate in plasma and red blood cell membranes of steroid sulfatase deficient patients.
Increased levels of DHEAS in serum of patients with X-linked ichthyosis.
Isolation and characterization of a steroid sulfatase cDNA clone: genomic deletions in patients with X-chromosome-linked ichthyosis.
Kallmann syndrome and ichthyosis: a case of contiguous gene deletion syndrome.
Keratinocyte lipid fluidity under the influence of cholesterols, hydrocortisones, "active lipid", tocopherol and retinoic acid--a fluorescence polarization study with regard to physiological and pathophysiological epidermopoiesis and its therapeutic accessibility.
Lipids in the pathogenesis of ichthyosis: topical cholesterol sulfate-induced scaling in hairless mice.
Lipoprotein electrophoresis in recessive X-linked ichthyosis.
Low estriol levels in the maternal triple-marker screen as a predictor of isolated adrenocorticotropic hormone deficiency caused by a new mutation in the TPIT gene.
Low maternal serum unconjugated estriol during prenatal screening as an indication of placental steroid sulfatase deficiency and X-linked ichthyosis.
Male-pattern baldness in men with X-linked recessive ichthyosis.
Male-pattern baldness is common in men with X-linked recessive ichthyosis.
Maternal serum unconjugated estriol as a predictor for Smith-Lemli-Opitz syndrome and other fetal conditions.
Measuring scale steroid sulfatase and beta-lipoprotein mobility in ichthyosis.
Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank.
Metabolism of 3H-dehydroepiandrosterone sulphate by subjects with steroid sulphatase deficiency.
Mild ichthyosis in a 4-year-old boy with multiple sulphatase deficiency.
Molecular analysis of X-linked ichthyosis in Japan.
Molecular heterogeneity of steroid sulfatase deficiency: a multicenter study on 57 unrelated patients, at DNA and protein levels.
Molecular studies of deletions at the human steroid sulfatase locus.
More on X-linked ichthyosis, steroid sulfatase deficiency, and hypogonadism and anosmia.
Most "sporadic" cases of X-linked ichthyosis are not de novo mutations.
Mutation report: a novel partial deletion of exons 2-10 of the STS gene in recessive X-linked ichthyosis.
Mutations in X-linked ichthyosis disrupt the active site structure of estrone/DHEA sulfatase.
Novel filaggrin mutation but no other loss-of-function variants found in ethiopian atopic-dermatitis patients.
Novel point mutations in the steroid sulfatase gene in patients with X-linked ichthyosis: transfection analysis using the mutated genes.
Oral fluconazole treatment of fungating candidiasis in the keratitis, ichthyosis and deafness (KID) syndrome.
Palmoplantar keratoderma with an unusual composition of stratum corneum and serum sterol derivatives: a new entity?
Partial lyonisation of steroid sulphatase gene in single hair roots.
PCR diagnosis of X-linked ichthyosis: identification of a novel mutation (E560P) of the steroid sulfatase gene.
Physical mapping of deletion breakpoints in patients with X-linked ichthyosis: evidence for clustering of distal and proximal breakpoints.
Placental steroid sulphatase deficiency.
Placental steroid sulphatase deficiency: an approach to antenatal care and delivery.
Placental sulfatase deficiency: maternal and fetal expression of steroid sulfatase deficiency and X-linked ichthyosis.
Pre-Descemet corneal dystrophy and X-linked ichthyosis associated with deletion of Xp22.31 containing the STS gene.
Prenatal detection of X-linked ichthyosis by maternal serum screening for Down syndrome.
Prenatal diagnosis of X-linked ichthyosis using molecular cytogenetics.
Prenatal diagnosis of X-linked ichthyosis.
Prenatal in situ hybridization test for deleted steroid sulfatase gene.
Rapid laboratory diagnostic of X-linked ichthyosis.
Recessive X-linked ichthyosis: lack of immunologically detectable steroid sulfatase enzyme protein.
Recurrent bilateral corneal erosions due to an association of epidermolysis bullosa simplex Köbner and X-linked ichthyosis with steroid sulfatase deficiency.
Regional assignment of the gene locus for steroid sulfatase.
Renal dysgenesis and KAL1 gene defects in patients with sporadic Kallmann syndrome.
Review: genetics of steroid sulphatase deficiency and X-linked ichthyosis.
Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis.
Role of the pseudoautosomal region in sex-chromosome pairing during male meiosis: meiotic studies in a man with a deletion of distal Xp.
Serum steroid sulphates in ichthyosis.
Sex-linked ichthyosis and placental sulphatase C deficiency.
Somatic and germinal mosaicism for the steroid sulfatase gene deletion in a steroid sulfatase deficiency carrier.
Steroid sulfatase = aryl sulfatase C? Chromatographic and electrophoretic properties in extracts from placental microsomes and skin fibroblasts.
Steroid sulfatase activity in human leukocytes.
Steroid sulfatase activity in nails: screening for X-linked ichthyosis.
Steroid sulfatase and filaggrin mutations in a boy with severe ichthyosis, elevated serum IgE level and moyamoya syndrome.
Steroid sulfatase deficiency and X-linked ichthyosis.
Steroid sulfatase deficiency in Japanese patients: characterization of X-linked ichthyosis by using polymerase chain reaction.
Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis.
Steroid sulfatase, X-linked ichthyosis, and stratum corneum cell cohesion.
Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts.
Steroid sulphatase activity in the skin biopsies of various types of ichthyosis.
Steroid sulphatase deficiency associated with testis cancer.
Steroid sulphatase deficiency disease.
Steroid sulphatase deficiency in patients initially diagnosed as ichthyosis vulgaris or recessive X-linked ichthyosis.
Steroid sulphatase deficiency: identification of heterozygotes using hydrolysis of dehydroepiandrosterone sulphate by peripheral leucocytes.
Steroid sulphatase in man: a non inactivated X-locus with partial gene dosage compensation.
Steroid-resistant nephrotic syndrome associated with steroid sulfatase deficiency-x-linked recessive ichthyosis: a case report and review of literature.
Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.
Stratum corneum lipids in disorders of cornification: increased cholesterol sulfate content of stratum corneum in recessive x-linked ichthyosis.
Submicroscopic Xpter deletion in a boy with growth and mental retardation caused by a familial t(X;14).
Substrate specific sulfatase activity from hair follicles in recessive X-linked ichthyosis.
Sulfatase activity of keratinizing tissues in X-linked ichthyosis.
Testis cancer. Ichthyosis constitutes a significant risk factor.
The biochemical identification of carrier state in mothers of sporadic cases of X-linked recessive ichthyosis.
The detection of steroid sulfatase gene deletion (STS) in Egyptian males with X-linked ichthyosis.
The effect of steroid sulphatase on stratum corneum shedding in patients with X-linked ichthyosis.
The phenotype spectrum of X-linked ichthyosis identified by chromosomal microarray.
Two cases of steroid sulfatase deficiency with complex phenotype due to contiguous gene deletions.
Updated molecular genetics and pathogenesis of ichthiyoses.
X-chromosome inactivation: role in skin disease expression.
X-linkage of steroid sulphatase in the mouse is evidence for a functional Y-linked allele.
X-linked dominant chondrodysplasia punctata with decreased dihydroxyacetone phosphate acyltransferase activity.
X-linked ichthyosis (steroid sulfatase deficiency) is associated with increased risk of attention deficit hyperactivity disorder, autism and social communication deficits.
X-linked ichthyosis along with epidermolysis bullosa.
X-linked ichthyosis and ichthyosis vulgaris: comparison of their clinical features based on biochemical analysis.
X-linked ichthyosis and X-linked placental sulfatase deficiency: a disease entity. Histochemical observations.
X-linked ichthyosis associated with psychosis and behavioral abnormalities: a case report.
X-linked ichthyosis due to steroid sulfatase deficiency associated with hypogonadism and anosmia.
X-linked ichthyosis in Mexico: high frequency of deletions in the steroid sulfatase encoding gene.
X-linked ichthyosis with hypogonadism: not always Kallmann's syndrome.
X-linked ichthyosis without STS deficiency: clinical, genetical, and molecular studies.
X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome.
X-linked ichthyosis: a metabolic disease.
X-linked ichthyosis: Clinical and molecular findings in 35 Italian patients.
X-linked ichthyosis: increased blood cholesterol sulfate and electrophoretic mobility of low-density lipoprotein.
X-linked ichthyosis: relation between cholesterol sulphate, dehydroepiandrosterone sulphate and patient's age.
X-linked recessive ichthyosis. Enzymatic diagnosis of affected males and female carriers.
X-linked recessive ichthyosis. Reinvestigation of a family first described in 1928.
X-linked recessive ichthyosis: an impaired barrier function evokes limited gene responses before and after moisturizing treatments.
X/Y translocation in a family with X-linked ichthyosis, chondrodysplasia punctata, and mental retardation: DNA analysis reveals deletion of the steroid sulphatase gene and translocation of its Y pseudogene.
X?linked ichthyosis and Crigler?Najjar syndrome ?: Coexistence in a male patient with two copy number variable regions of 2q37.1 and Xp22.3.
Xp22.3 deletions in isolated familial Kallmann's syndrome.
Xp22.3 interstitial deletion: A recognizable chromosomal abnormality encompassing VCX3A and STS genes in a patient with X-linked ichthyosis and mental retardation.
[A Case of Steroid Sulfatase Deficiency Complicated by Bilateral Undescended Testis].
[Arylsulfatase C deficiency in leukocytes in patients and carrier of X-chromosome recessive ichthyosis]
[Biochemical diagnosis of X chromosomal ichthyosis]
[Biochemical study on steroid sulfatase and its clinical application to the obstetrics and gynecology]
[Functional consequences of cutaneous lipid perturbation]
[Hope for new therapies of severe genetic skin diseases]
[Ichthyosis and steroid sulfatase: study of enzymatic activity in leukocytes and fibroblasts according to the sex and type of ichthyosis]
[Ichthyosis X. Clinical review and rapid identification using lipid electrophoresis]
[Identification of gene mutation and prenatal diagnosis in a family with X-linked ichthyosis].
[Investigation of steroid sulfatase gene in two pedigrees with X-linked ichthyosis]
[Occurrence of X-linked ichthyosis along with atopy]
[Progress in dermatology: new biochemical aspects]
[The enzyme arylsulfatase C and steroid sulfatase as biochemical markers and pathogenetic factors in X-chromosome recessively inherited ichthyosis]
[The genetics and molecular genetics of X-chromosomal recessive ichthyosis]
[Two cases of X-linked ichthyosis associated with myopathies]
[X-chromosomal recessive ichthyosis. Detection of heterozygote status in genetically possible carriers by determination of arylsulfatase C activity]
[X-chromosome-linked ichthyosis associated to epilepsy, hyperactivity, autism and mental retardation, due to the Xp22.31 microdeletion].
[X-linked recessive ichthyosis (XRI), cerebellar ataxia and neuropsychiatric symptoms].
Ichthyosis Vulgaris
Elevated levels of arylsulfatase C activity in cultured skin fibroblasts of patients with autosomal dominant ichthyosis vulgaris.
Ichthyosis vulgaris with hypogenitalism and hypogonadism: evidence for different genotypes by lipoprotein electrophoresis and steroid sulfatase testing.
Steroid sulphatase deficiency in patients initially diagnosed as ichthyosis vulgaris or recessive X-linked ichthyosis.
X-linked ichthyosis and ichthyosis vulgaris: comparison of their clinical features based on biochemical analysis.
Ichthyosis, X-Linked
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Are low maternal estriol levels a predictor for pro-opiomelanocortin (POMC) deficiency caused by POMC mutation during pregnancy?
Association of undetectable unconjugated estriol on multiple marker screening with steroid sulfatase deficiency.
Banding pattern on polarized hair microscopic examination and unilateral polymicrogyria in a patient with steroid sulfatase deficiency.
Characterization of a low copy repetitive element S232 involved in the generation of frequent deletions of the distal short arm of the human X chromosome.
Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis.
Characterization of the deletion breakpoints in a patient with steroid sulfatase deficiency.
Clinical pathologic correlation of superficial corneal opacities in X-linked ichthyosis.
Clinical spectrum of steroid sulfatase deficiency: X-linked recessive ichthyosis, birth complications and cryptorchidism.
Congenital hypopituitarism as a cause of undetectable estriol levels in the maternal triple-marker screen.
Contiguous gene syndromes due to deletions in the distal short arm of the human X chromosome.
Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis.
Deletion of exons 1-5 of the STS gene causing X-linked ichthyosis.
Deletion of the distal short arm of the X chromosome (Xp) in a patient with short stature, chondrodysplasia punctata, and X-linked ichthyosis due to steroid sulfatase deficiency.
Deletion pattern of the STS gene in X-linked ichthyosis in a Mexican population.
Does steroid sulfatase deficiency influence postpartum psychosis risk?
Dosage of the Sts gene in the mouse.
Enzymatic diagnosis of steroid sulfatase deficiency by high performance liquid chromatography.
Familial X-linked ichthyosis, steroid sulfatase deficiency, mental retardation, and nullisomy for Xp223-pter.
Frequency of steroid sulfatase deficiency in Hiroshima.
Frequent deletions of the human X chromosome distal short arm result from recombination between low copy repetitive elements.
Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase.
High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency.
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Increased cholesterol sulfate in plasma and red blood cell membranes of steroid sulfatase deficient patients.
Low maternal serum unconjugated estriol during prenatal screening as an indication of placental steroid sulfatase deficiency and X-linked ichthyosis.
Low or absent unconjugated estriol in pregnancy: an indicator for steroid sulfatase deficiency detectable by fluorescence in situ hybridization and biochemical analysis.
Maternal serum unconjugated estriol as a predictor for Smith-Lemli-Opitz syndrome and other fetal conditions.
Maternal steroid sulfatase deficiency--cause of high-risk pregnancy?
Maternal transmission of the 3 bp deletion within exon 7 of the STS gene in steroid sulfatase deficiency.
Maternal urine and serum steroid measurements to identify steroid sulfatase deficiency (STSD) in second trimester pregnancies.
Molecular heterogeneity of steroid sulfatase deficiency: a multicenter study on 57 unrelated patients, at DNA and protein levels.
More on X-linked ichthyosis, steroid sulfatase deficiency, and hypogonadism and anosmia.
Multipoint linkage analysis of steroid sulfatase (X-linked ichthyosis) and distal Xp markers.
Mutation report: a novel partial deletion of exons 2-10 of the STS gene in recessive X-linked ichthyosis.
Nonsyndromic types of ichthyoses - an update.
Novel point mutations in the steroid sulfatase gene in patients with X-linked ichthyosis: transfection analysis using the mutated genes.
Ocular findings in X-linked ichthyosis: a survey on 38 cases.
Placental steroid deficiency: association with arylsulfatase A deficiency.
Placental steroid sulfatase deficiency.
Placental steroid sulfatase deficiency: biochemical diagnosis and clinical review.
Placental sulfatase deficiency: maternal and fetal expression of steroid sulfatase deficiency and X-linked ichthyosis.
Prenatal diagnosis of placental steroid sulfatase deficiency.
Prenatal diagnosis of sex differentiation disorders: the role of fetal ultrasound.
Prenatal diagnosis of X-linked ichthyosis using molecular cytogenetics.
Prenatal diagnosis of X-linked ichthyosis.
Prevalence of steroid sulfatase deficiency in California according to race and ethnicity.
Recurrent bilateral corneal erosions due to an association of epidermolysis bullosa simplex Köbner and X-linked ichthyosis with steroid sulfatase deficiency.
Regional assignment of the gene locus for steroid sulfatase.
Regulation of serum testosterone in men with steroid sulfatase deficiency: response to human chorionic gonadotropin.
Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency.
Role of the pseudoautosomal region in sex-chromosome pairing during male meiosis: meiotic studies in a man with a deletion of distal Xp.
Sequence analysis of a partial deletion of the human steroid sulfatase gene reveals 3 bp of homology at deletion breakpoints.
Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS.
Somatic and germinal mosaicism for the steroid sulfatase gene deletion in a steroid sulfatase deficiency carrier.
Steroid sulfatase activity in human leukocytes.
Steroid sulfatase activity in leukocytes: a comparative study in 45,X; 46,Xi(Xq) and carriers of steroid sulfatase deficiency.
Steroid sulfatase deficiency and contiguous gene deletion syndrome amongst pregnant patients with low serum unconjugated estriols.
Steroid sulfatase deficiency and the genetics of the short arm of the human X chromosome.
Steroid sulfatase deficiency and X-linked ichthyosis.
Steroid sulfatase deficiency in Japanese patients: characterization of X-linked ichthyosis by using polymerase chain reaction.
Steroid Sulfatase Deficiency With Bilateral Periventricular Nodular Heterotopia.
Steroid sulfatase deficiency.
Steroid sulfatase deficiency: enzymatic studies using placenta and leucocytes in one family.
Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder.
Steroid-resistant nephrotic syndrome associated with steroid sulfatase deficiency-x-linked recessive ichthyosis: a case report and review of literature.
The human arylsulfatase-C isoenzymes: two distinct genes that escape from X inactivation.
Two cases of steroid sulfatase deficiency with complex phenotype due to contiguous gene deletions.
Unconjugated estriol as an indication for prenatal diagnosis of steroid sulfatase deficiency by in situ hybridization.
Very low maternal serum unconjugated estriol and prenatal diagnosis of steroid sulfatase deficiency.
X-linked ichthyosis and X-linked placental sulfatase deficiency: a disease entity. Histochemical observations.
X-linked ichthyosis due to steroid sulfatase deficiency associated with hypogonadism and anosmia.
X-linked recessive ichthyosis. Enzymatic diagnosis of affected males and female carriers.
[A Case of Steroid Sulfatase Deficiency Complicated by Bilateral Undescended Testis].
[Biochemical study on steroid sulfatase and its clinical application to the obstetrics and gynecology]
[Genetic analysis of a rare case with Kallman syndrome and steroid sulfatase deficiency].
[Identification of gene mutation and prenatal diagnosis in a family with X-linked ichthyosis].
[Placental steroid sulfatase deficiency. Reduced estriol production]
[Steroid sulfatase and placental deficiency. Current data as instigators of new research]
[Two cases of X-linked ichthyosis associated with myopathies]
Infections
Cytokine dysregulation and increased oxidation is prevented by dehydroepiandrosterone in mice infected with murine leukemia retrovirus.
Dehydroepiandrosterone sulphate and androstenedione concentration in the serum of male patients with chronic hepatitis C.
Higher serum concentrations of DHEAS predict improved nutritional status in helminth-infected children, adolescents, and young adults in Leyte, the Philippines.
HIV-1 clade C infection and progressive disruption in the relationship between cortisol, DHEAS and CD4 cell numbers: a two-year follow-up study.
Raised cortisol:DHEAS ratios in the elderly after injury: potential impact upon neutrophil function and immunity.
The relationships between dehydroepiandrosterone sulphate (DHEAS), the intensity of Schistosoma mansoni infection and parasite-specific antibody responses. A cross-sectional study in residents of endemic communities in north-east Ethiopia.
Infertility
Age related endocrine patterns observed in polycystic ovary syndrome patients vs. ovulatory controls: descriptive data from a university based infertility center.
Clomiphene citrate and dexamethazone in treatment of clomiphene citrate-resistant polycystic ovary syndrome: a prospective placebo-controlled study.
Peritoneal fluid from patients with unexplained infertility inhibits growth of 2-cell mouse embryos.
Plasma homocysteine, fasting insulin, and androgen patterns among women with polycystic ovaries and infertility.
Serum levels of DHEAS in gynecologic endocrinopathy and infertility.
The effect of dehydroepiandrosterone sulfate prolactin and testosterone hormones in female fertility and hirsutism.
Infertility, Female
The effect of dehydroepiandrosterone sulfate prolactin and testosterone hormones in female fertility and hirsutism.
Infertility, Male
Serum reproductive hormone levels and ultrasound findings in female offspring after intracytoplasmic sperm injection: first results.
Inflammatory Bowel Diseases
Association of humoral markers of inflammation and dehydroepiandrosterone sulfate or cortisol serum levels in patients with chronic inflammatory bowel disease.
Influenza, Human
DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies.
The development of effective vaccine adjuvants employing natural regulators of T-cell lymphokine production in vivo.
The effect of DHEAS on influenza vaccination in aging adults.
The use of oral dehydroepiandrosterone sulfate as an adjuvant in tetanus and influenza vaccination of the elderly.
Insulin Resistance
A close association between insulin resistance and dehydroepiandrosterone sulfate in subjects with essential hypertension.
A Twin-Sibling Study on Early Growth and Hormone Levels in Adolescents.
Acute hyperinsulinemia, androgen homeostasis and insulin sensitivity in healthy man.
Androgens and insulin resistance in type 1 diabetic men.
Association of Luteinizing hormone and LH receptor gene polymorphism with susceptibility of Polycystic ovary syndrome.
Body mass index at the presentation of premature adrenarche is associated with components of metabolic syndrome at puberty.
Can metformin reduce insulin resistance in polycystic ovary syndrome?
Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
Dehydroepiandrosterone Sulfate (DHEAS) Levels in Polycystic Ovarian Syndrome (PCOS).
Dehydroepiandrosterone sulfate and insulin resistance in patients with polycystic ovary syndrome.
Effect of hyperprolactinemia on the androgen response to an oral glucose load.
Effect of metformin on serum visfatin levels in patients with polycystic ovary syndrome.
Effects of exercise training on plasma androgens in men.
Familial clustering of metabolic phenotype in brothers of women with polycystic ovary syndrome.
Functional correlates of detailed body composition in healthy elderly subjects.
Heterogenous origins of hyperandrogenism in the polycystic ovary syndrome in relation to body mass index and insulin resistance.
Higher steroid sulfation is linked to successful weight loss in obese children.
Hyperinsulinemia and circulating dehydroepiandrosterone sulfate in white and Mexican American women with polycystic ovary syndrome.
In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake.
Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?
Increased plasma thrombin-activatable fibrinolysis inhibitor levels in young obese women with polycystic ovary syndrome.
Is there a relationship between cardiovascular risk factors and dehydroepiandrosterone sulfate levels in childhood obesity?
Low dehydroepiandrosterone sulfate is associated with increased risk of ischemic stroke among women.
MIFEPRISTONE TREATMENT FOR MILD AUTONOMOUS CORTISOL SECRETION DUE TO ADRENAL ADENOMAS: A PILOT STUDY.
Myostatin and its association with abdominal obesity, androgen and follistatin levels in women with polycystic ovary syndrome.
Obesity is the major factor determining an insulin sensitivity and androgen production in women with anovulary cycles.
Opposing effects of dehydroepiandrosterone sulfate and free testosterone on metabolic phenotype in women with polycystic ovary syndrome.
Polycystic ovary syndrome is associated with elevated plasma soluble CD40 ligand, a marker of coronary artery disease.
Recommendations for investigation of hyperandrogenism.
Relation between adiponectin and bone mineral density in elderly post-menopausal women: role of body composition, leptin, insulin resistance, and dehydroepiandrosterone sulfate.
Relationship between the GH/IGF-I axis, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal boys.
Serum 25-hydroxyvitamin D concentrations in obese and non-obese women with polycystic ovary syndrome.
Serum soluble leptin receptor levels and free leptin index in women with polycystic ovary syndrome: relationship to insulin resistance and androgens.
Serum Zinc and Adiponectin Levels in Patients with Polycystic Ovary Syndrome, Adjusted for Anthropometric, Biochemical, Dietary Intake, and Physical Activity Measures.
Short-term metformin treatment for clomiphene citrate-resistant women with polycystic ovary syndrome.
The association of dehydroepiandrosterone, obesity, waist-hip ratio and insulin resistance with fatty liver in postmenopausal women--a hyperinsulinemic euglycemic insulin clamp study.
The link between metabolic features and TSH levels in polycystic ovary syndrome is modulated by the body weight: an euglycemic-hyperinsulinemic clamp study.
The severity of menstrual dysfunction as a predictor of insulin resistance in PCOS.
The Unique Role of 11-Oxygenated C19 Steroids in Both Premature Adrenarche and Premature Pubarche.
Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome.
[A relationship between dehydroepiandrosterone sulphate and insulin resistance in obese men and women]
Intellectual Disability
Analysis of an interstitial deletion in a patient with Kallmann syndrome, X-linked ichthyosis and mental retardation.
Contiguous gene syndromes due to deletions in the distal short arm of the human X chromosome.
Familial X-linked ichthyosis, steroid sulfatase deficiency, mental retardation, and nullisomy for Xp223-pter.
Role of the pseudoautosomal region in sex-chromosome pairing during male meiosis: meiotic studies in a man with a deletion of distal Xp.
Unusual presentation of Kallmannn syndrome with contiguous gene deletion in three siblings of a family.
X/Y translocation in a family with X-linked ichthyosis, chondrodysplasia punctata, and mental retardation: DNA analysis reveals deletion of the steroid sulphatase gene and translocation of its Y pseudogene.
Ischemic Stroke
Low dehydroepiandrosterone sulfate is associated with increased risk of ischemic stroke among women.
Kallmann Syndrome
A yeast artificial chromosome contig linking the steroid sulfatase and Kallmann syndrome loci on the human X chromosome short arm.
Contiguous gene syndrome due to deletion of the first three exons of the Kallmann gene and complete deletion of the steroid sulphatase gene.
Contiguous gene syndromes due to deletions in the distal short arm of the human X chromosome.
Deletion analysis maps ocular albinism proximal to the steroid sulphatase locus.
Deletions of the steroid sulphatase gene in "classical" X-linked ichthyosis and in X-linked ichthyosis associated with Kallmann syndrome.
Hypogonadotrophic hypogonadism with hyposmia, X-linked ichthyosis, and renal malformation syndrome.
Isolation of a new gene GS2 (DXS1283E) from a CpG island between STS and KAL1 on Xp22.3.
Kallmann syndrome and ichthyosis: a case of contiguous gene deletion syndrome.
Long-range physical mapping around the human steroid sulfatase locus.
Long-range restriction map of the terminal part of the short arm of the human X chromosome.
Prenatal diagnosis and investigation of a fetus with chondrodysplasia punctata, ichthyosis, and Kallmann syndrome due to an Xp deletion.
Unconjugated estriol as an indication for prenatal diagnosis of steroid sulfatase deficiency by in situ hybridization.
X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome.
Leiomyoma
Estrone sulfatase activity in human uterine leiomyoma.
[Study on the local estrogen biosynthesis in human uterine leiomyoma]
Leukemia, Myeloid, Acute
Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways.
Leukodystrophy, Metachromatic
Enzymic detection of metachromatic leukodystrophy patients and heterozygotes.
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Juvenile metachromatic leukodystrophy: deficiency of an arylsufatase A component.
Steroid sulfatase in brain: comparison of sulfohydrolase activities for various steroid sulfates in normal and pathological brains, including the various forms of metachromatic leukodystrophy.
Li-Fraumeni Syndrome
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Liver Cirrhosis
Dehydroepiandrosterone sulfate and dehydroepiandrosterone sulfate/cortisol ratio in cirrhotic patients with septic shock: another sign of hepatoadrenal syndrome?
Liver Diseases
Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease.
Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy.
Liver Failure
Dehydroepiandrosterone sulphate improves cholestasis-associated fatigue in bile duct ligated rats.
Liver Neoplasms
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
Lung Diseases
Cardiovascular disease is associated with greater incident dehydroepiandrosterone sulfate decline in the oldest old: the cardiovascular health study all stars study.
Lupus Erythematosus, Systemic
Adrenal androgens and the immune system.
Blood dehydroepiandrosterone sulphate (DHEAS) levels in polymyalgia rheumatica/giant cell arteritis and primary fibromyalgia.
Lymphopenia
DHEAS and Differential Blood Counts as Indirect Signs of Glucocorticoid Excess in Adrenal Non-Producing Adenomas.
Malnutrition
Higher serum concentrations of DHEAS predict improved nutritional status in helminth-infected children, adolescents, and young adults in Leyte, the Philippines.
Mania
Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder.
Melanoma
Serum dehydroepiandrosterone and dehydroepiandrosterone sulfate and risk of melanoma or squamous cell carcinoma of the skin.
Memory Disorders
DHEAS improves learning and memory in aged SAMP8 mice but not in diabetic mice.
Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice.
Effects of sigma(1) receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats.
Meningeal Carcinomatosis
Neurosteroids in cerebrospinal fluid in neurologic disorders.
Metabolic Diseases
Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis.
[Identification of gene mutation and prenatal diagnosis in a family with X-linked ichthyosis].
Metabolic Syndrome
Cortisol and DHEAS Related to Metabolic Syndrome in Patients with Schizophrenia.
Cortisol, DHEAS, their ratio and the metabolic syndrome: evidence from the Vietnam Experience Study.
Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue.
The role of genetic variation in the Lamin A/C gene in the etiology of Polycystic Ovary Syndrome.
[Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?]
[ROLE OF CAPSAICIN-SENSITIVE NERVES IN THE REGULATION OF DEHYDROEPIANDROSTERONE SULFATE BLOOD CONTENT UNDER NORMAL AND FRUCTOSE-INDUCED METABOLIC SYNDROME].
Metabolism, Inborn Errors
Molecular studies of deletions at the human steroid sulfatase locus.
Migraine Disorders
Sugar alters the level of serum insulin and plasma glucose and the serum cortisol:DHEAS ratio in female migraine sufferers.
Moyamoya Disease
Steroid sulfatase and filaggrin mutations in a boy with severe ichthyosis, elevated serum IgE level and moyamoya syndrome.
Mucocele
Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation.
Multiple Endocrine Neoplasia
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Multiple Endocrine Neoplasia Type 1
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Multiple Sulfatase Deficiency Disease
Arylsulfatases A and B in EBV-transformed lymphoid cell lines: studies on their molecular forms in cells from patients with inborn sulfatase deficiencies. Comparative diagnostic value of enzymatic assays.
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Rapid degradation of steroid sulfatase in multiple sulfatase deficiency.
Synthesis and stability of steroid sulfatase in fibroblasts from multiple sulfatase deficiency.
Murine Acquired Immunodeficiency Syndrome
Immune dysfunction during alcohol consumption and murine AIDS: the protective role of dehydroepiandrosterone sulfate.
Muscle Weakness
The effect of dehydroepiandrosterone sulfate (DHEAS) on myotonia: intracellular studies.
Muscular Dystrophies
A family with fragile X syndrome, Duchenne muscular dystrophy and ichthyosis transmitted by an asymptomatic carrier.
Muscular Dystrophy, Duchenne
Frequent deletions of the human X chromosome distal short arm result from recombination between low copy repetitive elements.
Myocardial Infarction
Dehydroepiandrosterone sulfate and the risk of myocardial infarction in US male physicians: a prospective study.
Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men.
Dehydroepiandrosterone, dehydroepiandrosterone sulphate and cardiovascular disease.
von Willebrand factor, tissue plasminogen activator, and dehydroepiandrosterone sulphate predict cardiovascular death in a 10 year follow up of survivors of acute myocardial infarction.
Myocardial Ischemia
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women. The Rancho Bernardo Study.
The epidemiology of DHEAS and cardiovascular disease.
Myotonia
A pilot study of dehydroepiandrosterone sulfate in myotonic dystrophy.
The effect of dehydroepiandrosterone sulfate (DHEAS) on myotonia: intracellular studies.
Myotonic Dystrophy
The effect of dehydroepiandrosterone sulfate (DHEAS) on myotonia: intracellular studies.
Neoplasm Metastasis
Arylsulfatase B regulates colonic epithelial cell migration by effects on MMP9 expression and RhoA activation.
Asymptomatic adrenal tumours: criteria for endoscopic removal.
Dehydroepiandrosterone sulfate (DHEAS) secretion in early and advanced solid neoplasms: selective deficiency in metastatic disease.
Neoplasm, Residual
Hormonal factors and prognosis in epithelial ovarian cancer: a multivariate analysis.
Neoplasms
17?-Arylsulfonamides of 17?-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase.
2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.
3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.
A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation.
Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe.
Adrenal and sex steroid hormone production by a virilizing adrenal adenoma and its diagnosis with computerized tomography.
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Anti-breast cancer potential of natural and synthetic coumarin derivatives.
Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates.
ANXA7 expression represents hormone-relevant tumor suppression in different cancers.
Aromatase and intracrinology of estrogen in hormone-dependent tumors.
Aromatase inhibitors and other novel agents in breast cancer treatment.
Bacterial Lipopolysaccharides Induce Steroid Sulfatase Expression and Cell Migration through IL-6 Pathway in Human Prostate Cancer Cells.
Breast cancer size in postmenopausal women is correlated with body mass index and androgen serum levels.
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors.
Cortisol, DHEA sulphate, their ratio, and all-cause and cause-specific mortality in the Vietnam Experience Study.
Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?
Decreased serum level of dehydroepiandrosterone sulfate in postmenopausal women with ovarian cancer.
Defect of a subpopulation of natural killer immune cells in Graves' disease and Hashimoto's thyroiditis: normalizing effect of dehydroepiandrosterone sulfate.
Dehydroepiandrosterone concentration in breast cancer tissue is related to its plasma gradient across the mammary gland.
Dehydroepiandrosterone sulfate (DHEAS) and testosterone: relation to HIV illness stage and progression over one year.
Dehydroepiandrosterone sulfate (DHEAS) secretion in early and advanced solid neoplasms: selective deficiency in metastatic disease.
Dehydroepiandrosterone sulfate, diseases and mortality in a general aged population.
Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men.
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Design and synthesis of carbon-11-labeled dual aromatase-steroid sulfatase inhibitors as new potential PET agents for imaging of aromatase and steroid sulfatase expression in breast cancer.
Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53.
Detection of a novel, primate-specific ‘kill switch’ tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53
Detection of breast cancer-associated estrone sulfatase in breast cancer biopsies and cell lines using polymerase chain reaction.
Development of (p-O-sulfamoyl)-N-alkanoyl-phenylalkyl amines as non-steroidal estrone sulfatase inhibitors.
Development of novel steroid sulfatase inhibitors; II. TZS-8478 potently inhibits the growth of breast tumors in postmenopausal breast cancer model rats.
Development of potent non-estrogenic estrone sulfatase inhibitors.
Development of steroid sulfatase inhibitors.
DHEAS for the prediction of subclinical Cushing's syndrome: perplexing or advantageous?
DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I.
Dietary intervention at middle age: caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice.
Differential effect of carbamazepine and valproate monotherapy on plasma levels of oestrone sulphate and dehydroepiandrosterone sulphate in male epileptic patients.
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
During a corticotropin-releasing hormone test in healthy subjects, administration of a beta-adrenergic antagonist induced secretion of cortisol and dehydroepiandrosterone sulfate and inhibited secretion of ACTH.
Early development of osteoporosis in male smokers with hypoandrogenism due to fascioliasis with or without schistosomiasis added by life style.
Early shifts of adrenal steroid synthesis before and after relief of short-term cholestasis.
Elevated steroid sulfatase expression in breast cancers.
Estrogen inhibits cell proliferation through in situ production in human thymoma.
Estrogen-metabolizing enzymes in breast cancers from women over the age of 80 years.
Estrogenicity, antiestrogenicity and estrone sulfatase inhibition of estrone-3-amine and estrone-3-thiol.
Estrone sulfatase activity in normal and abnormal endometrium.
Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6).
Evaluation of cytotoxic effects of several novel tetralin derivatives against Hela, MDA-MB-468, and MCF-7 cancer cells.
Evidence of in situ estrogen synthesis in nitrosomethylurea-induced rat mammary tumors via the enzyme estrone sulfatase.
Expression level of enzymes related to in situ estrogen synthesis and clinicopathological parameters in breast cancer patients.
Expression of sulfotransferases and sulfatases in human breast cancer: Impact on resveratrol metabolism.
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.
First dual aromatase-steroid sulfatase inhibitors.
From adrenarche to aging of adrenal zona reticularis: precocious female adrenopause onset.
Girls with virilisation in childhood: a diagnostic protocol for investigation.
Human granulosa cells are a site of sulphatase activity and are able to utilize dehydroepiandrosterone sulphate as a precursor for oestradiol production.
Human steroid sulfatase enhances aerobic glycolysis through induction of HIF1? and glycolytic enzymes.
Hyperandrogenism and Adrenocortical Tumors.
Immunohistochemical analysis of estrone sulfatase and aromatase in human breast cancer tissues.
Immunohistochemical analysis of steroid sulfatase in human tissues.
Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension.
In breast cancer subtypes steroid sulfatase (STS) is associated with less aggressive tumour characteristics.
In situ steroid sulfatase activity in human epithelial carcinoma cells of vaginal, ovarian, and endometrial origin.
In vitro evaluation of the interaction potential of irosustat with drug-metabolizing enzymes.
In vitro interactions between mammary fibroblasts (Hs 578Bst) and cancer epithelial cells (MCF-7) modulate aromatase, steroid sulfatase and 17?-hydroxysteroid dehydrogenases.
In Vitro Metabolism of Irosustat, a Novel Steroid Sulphatase Inhibitor: Inter-Species Comparison, Metabolite Identification and Metabolic Enzyme Identification.
In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE.
Increased DHEAS levels in patients with rheumatoid arthritis after treatment with tumor necrosis factor antagonists: evidence for improved adrenal function.
Increased serum cortisol levels are associated with high tumour grade in patients with renal cell carcinoma.
Induction of steroid sulfatase expression by tumor necrosis factor-? through phosphatidylinositol 3-kinase/Akt signaling pathway in PC-3 human prostate cancer cells.
Influence of estrogen metabolism on proliferation of human breast cancer.
Inhibition of estrone sulfatase activity by estrone-3-methylthiophosphonate: a potential therapeutic agent in breast cancer.
Inhibition of estrone sulfatase and proliferation of human breast cancer cells by nonsteroidal (p-O-sulfamoyl)-N-alkanoyl tyramines.
Inhibition of placental estrone sulfatase activity and MCF-7 breast cancer cell proliferation by estrone-3-amino derivatives.
Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: potential therapeutic agents in breast cancer.
Isolated dehydroepiandrosterone sulphate hypersecretion: a case report.
Localization of Estrone Sulfatase in Human Breast Carcinomas.
Marked hyperandrogenicity in a 60-year-old woman.
Measurement of serum levels of dehydroepiandrosterone sulfate: a comparison of radioimmunoassay and enzymatic analysis.
Microtiter plate cellular assay for human steroid sulfatase with fluorescence readout.
Oncological markers CA-125, CA 19-9 and endometriosis.
Peripheral and ovarian venous concentrations of steroid and gonadotropin hormones in postmenopausal women with epithelial ovarian tumors.
Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats.
Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery.
Predicting malignancy in adrenal incidentaloma and evaluation of a novel risk stratification algorithm.
Preneoplastic lesions and prognostic factors of breast cancer.
Prognostic significance of aromatase and estrone sulfatase enzymes in human breast cancer.
Quantitative analysis of aromatase, sulfatase and 17beta-HSD(1) mRNA expression in soft tissue metastases of breast cancer.
Recommendations for investigation of hyperandrogenism.
Reduced expression of steroid sulfatase in primary colorectal cancer.
Regulation of macrophage dehydroepiandrosterone sulfate metabolism by inflammatory cytokines.
Relation of Serum Levels of Estrogen and Dehydroepiandrosterone Sulfate to Hormone Receptor Status among Postmenopausal Women with Breast Cancer.
Role of OATP transporters in steroid uptake by prostate cancer cells in vivo.
Significance of Steroid Sulfatase Expression in Human Breast Cancer.
Simultaneous expression of steroid sulfatase and androgen receptor reduced overall survival of patients with epithelial ovarian tumors.
Simultaneous robotic-assisted adrenalectomy and partial nephrectomy: technical aspects.
Statin Use at the Time of Initiation of Androgen Deprivation Therapy and Time to Progression in Patients With Hormone-Sensitive Prostate Cancer.
Steroid hormones and human breast cancer. An hypothesis.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism.
Steroid sulfatase inhibitors for estrogen- and androgen-dependent cancers.
Steroid sulfatase: a new target for the endocrine therapy of breast cancer.
Strategic approach of hyperandrogenism in women.
Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495).
Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors.
Study of glucose tolerance in consecutive patients harbouring incidental adrenal tumours. Study Group of Incidental Adrenal Adenoma.
Sulfatase Activity in Normal and Neoplastic Endometrium.
Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review.
Sulfate derivatives of 2-phenylindoles as novel steroid sulfataseinhibitors. An in vitro study on structure-activity-relationship.
Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors.
Synthesis and sulfatase inhibitory activities of non-steroidal estrone sulfatase inhibitors.
Synthesis of 2-[11C]methoxy-3,17?-O,O-bis(sulfamoyl)estradiol as a new potential PET agent for imaging of steroid sulfatase (STS) in cancers.
Synthesis of a non-hydrolyzable estrone sulfate analogue bearing the difluoromethanesulfonamide group and its evaluation as a steroid sulfatase inhibitor.
The adrenal steroid status in relation to inflammatory cytokines (interleukin-6 and tumour necrosis factor) in polymyalgia rheumatica.
The development of steroid sulfatase inhibitors for hormone-dependent cancer therapy.
The hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate by MCF-7 human breast cancer cells.
THE RARE CASE OF MIXED GONADAL DYSGENESIS, MOSAIC KARYOTYPE, PETROCLIVAL MENINGIOMA AND IDIOPATHIC HYPERDEHYDROEPIANDROSTERONISM.
The role of cytokines and sulphatase inhibitors in regulating oestrogen synthesis in breast tumours.
The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors.
The treatment of a hyperandrogenic and virilizing state in an elderly female with a synthetic LHRH agonist.
The use of steroid sulfatase inhibitors as a novel therapeutic strategy against hormone-dependent endometrial cancer.
Total testosterone and DHEAS levels as predictors of androgen-secreting neoplasms: a populational study.
Unusual Visualization of an Adrenal Carcinoma on NP-59 Scintiscan.
Using molecular docking to investigate the anti-breast cancer activity of low molecular weight compounds present on wild mushrooms.
V89L polymorphism of the 5alpha-reductase Type II gene (SRD5A2), endogenous sex hormones, and prostate cancer risk.
Very High Dehydroepiandrosterone Sulfate (DHEAS) in Serum of an Overweight Female Adolescent Without a Tumor.
[Hyperandrogenism in premenopausal women]
[Molecular mechanisms of DHEA and DHEAs on apoptosis and cell cycle arrest via Akt pathway in hepatoma cell lines]
[Replacement therapy in adrenopause. Dehydroepiandrosterone and aging]
[Sertoli-Leydig cell tumour (arrhenoblastoma) in a patient with polycystic ovary syndrome: clinical, ultrasonographic, hormonal and histopathological evaluation]
[Tissue culture and estrogen, to clarify the roles of estrone sulfate]
Nephrotic Syndrome
Steroid-resistant nephrotic syndrome associated with steroid sulfatase deficiency-x-linked recessive ichthyosis: a case report and review of literature.
Nervous System Diseases
Physiological implications of DHEAS-induced non-classical steroid hormone signaling.
The effect of dehydroepiandrosterone sulfate administration to patients with multi-infarct dementia.
Neural Tube Defects
Second-trimester maternal serum screening using alpha-fetoprotein, human chorionic gonadotrophin, and unconjugated oestriol: experience of a regional programme.
Neuralgia
Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain.
Neuroblastoma
Effect of dehydroepiandrosterone and its sulfate metabolite on neuronal cell viability in culture.
Expression of the neuron-specific protein, 14-3-2, and steroid sulfatase in neuroblastoma cell hybrids.
Neurodegenerative Diseases
Actions of dehydroepiandrosterone and its sulfate in the central nervous system: effects on cognition and emotion in animals and humans.
Astrocyte Neuroprotection and Dehydroepiandrosterone.
Preclinical development of neurosteroids as neuroprotective agents for the treatment of neurodegenerative diseases.
Studies on homocysteine and dehydroepiandrosterone sulphate plasma levels in Alzheimer's disease patients and in Parkinson's disease patients.
Neuroinflammatory Diseases
Neuroprotective Effects of Dehydroepiandrosterone Sulfate Through Inhibiting Expression of Matrix Metalloproteinase-9 from Bradykinin-Challenged Astroglia.
Neurologic Manifestations
A new syndrome of anosmia, ichthyosis, hypogonadism, and various neurological manifestations with deficiency of steroid sulfatase and arylsulfatase C.
Non-alcoholic Fatty Liver Disease
Endocrine factors associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome: Do androgens play a role?
Serum dehydroepiandrosterone sulphate levels in patients with non-alcoholic Fatty liver disease.
Obesity
A prospective study of dehydroepiandrosterone sulfate (DHEAS) and bone mineral density in older men and women.
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
A study of insulin resistance in subjects with acanthosis nigricans.
Age-related decline in salivary dehydroepiandrosterone sulfate and associated health risks among African Americans.
Dehydroepiandrosterone reduces proliferation and differentiation of 3T3-L1 preadipocytes.
Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women. The Rancho Bernardo Study.
Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study.
Differential Effects of Various Androgens on Polycystic Ovary Syndrome.
GG-genotype in the promotor region of uncoupling-protein-1 gene is associated with lower level of dehydroepiandrosterone in type 2 diabetes.
Hepatic Overexpression of Steroid Sulfatase Ameliorates Mouse Models of Obesity and Type 2 Diabetes through Sex-specific Mechanisms.
In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake.
Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: prospective results from the Massachusetts Male Aging Study.
Low dehydroepiandrosterone sulfate and heart disease in middle-aged men: cross-sectional results from the Massachusetts Male Aging Study.
No acute effect of physiological insulin increase on dehydroepiandrosterone sulfate in women with obesity and/or polycystic ovarian disease.
Obesity affects circulating estradiol levels of premenopausal hirsute women receiving leuprolide acetate depot.
Predictors of sex hormone levels among the elderly: a study in Greece.
The association between dehydroepiandosterone and frailty in older men and women.
The association of dehydroepiandrosterone, obesity, waist-hip ratio and insulin resistance with fatty liver in postmenopausal women--a hyperinsulinemic euglycemic insulin clamp study.
The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women.
[The influence of obesity on sexual development in pubertal children]
[The relationship between serum dehydroepiandrosterone sulfate levels and factors associated with cardiovascular diseases: a cross-sectional study in Japan]
Obesity, Abdominal
Allostatic Load as a Biological Substrate to Intrinsic Capacity: A Secondary Analysis of CRELES.
Dehydroepiandrosterone sulfate and testosterone are independently associated with body fat distribution in premenopausal women.
Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: the Rancho Bernardo Study.
Myostatin and its association with abdominal obesity, androgen and follistatin levels in women with polycystic ovary syndrome.
Obesity, Morbid
Role of dehydroepiandrosterone sulfate levels on body composition after laparoscopic adjustable gastric banding in pre-menopausal morbidly obese women.
Serum concentrations of dehydroepiandrosterone sulfate and leptin in obese patients with normal serum cholesterol.
Opportunistic Infections
Dehydroepiandrosterone sulfate (DHEAS) and testosterone: relation to HIV illness stage and progression over one year.
Osteoarthritis
Blood dehydroepiandrosterone sulphate (DHEAS) levels in pemphigoid/pemphigus and psoriasis.
Blood dehydroepiandrosterone sulphate (DHEAS) levels in polymyalgia rheumatica/giant cell arteritis and primary fibromyalgia.
Relationship between blood and joint tissue DHEAS levels in rheumatoid arthritis and osteoarthritis.
Osteoporosis
A prospective study of dehydroepiandrosterone sulfate (DHEAS) and bone mineral density in older men and women.
Carnitine and dehydroepiandrosterone sulfate induce protein synthesis in porcine primary osteoblast-like cells.
CYP3A7*1C polymorphism, serum dehydroepiandrosterone sulfate level, and bone mineral density in postmenopausal women.
Dehydroepiandrosterone and Bone.
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Effects of age on serum dehydroepiandrosterone sulfate, IGF-I, and IL-6 levels in women.
Replacement therapy with DHEA plus corticosteroids in patients with chronic inflammatory diseases--substitutes of adrenal and sex hormones.
Serum dehydroepiandrosterone sulfate, testosterone, and biochemical markers of bone turnover in elderly Thai men.
Sex hormone status and osteoporosis in postmenopausal women with rheumatoid arthritis.
Sex hormones and quantitative ultrasound parameters at the heel in men and women from the general population.
Treatment of osteoporosis in men using dehydroepiandrosterone sulfate.
[Could serum DHEA and DHEAS levels be good risk predictors of metabolic syndrome and osteoporosis in the population of ageing men?]
[Dehydroepiandrosterone (DHEA)--slows down the aging process?]
[Reduced serum dehydroepiandrosterone levels in postmenopausal osteoporosis]
[Replacement therapy in adrenopause. Dehydroepiandrosterone and aging]
Ovarian Neoplasms
Circulating levels of sex steroid hormones and risk of ovarian cancer.
Decreased serum level of dehydroepiandrosterone sulfate in postmenopausal women with ovarian cancer.
Estrone sulfatase activity in patients with advanced ovarian cancer.
Peripheral and ovarian venous concentrations of steroid and gonadotropin hormones in postmenopausal women with epithelial ovarian tumors.
Overweight
From adrenarche to aging of adrenal zona reticularis: precocious female adrenopause onset.
Hyperandrogenemia in women with polycystic ovary syndrome: prevalence, characteristics and association with body mass index.
Maternal Pre-pregnancy BMI and Reproductive Health of Daughters in Young Adulthood.
Plasma lipids, dehydroepiandosterone sulphate and insulin concentrations in elderly overweight angina patients, and effect of weight loss.
The epidemiology of DHEAS and cardiovascular disease.
Trajectories of Growth and Serum DHEAS and IGF-1 Concentrations in Girls With a History of Premature Adrenarche: Attenuation of the Phenotype by Adulthood.
Very High Dehydroepiandrosterone Sulfate (DHEAS) in Serum of an Overweight Female Adolescent Without a Tumor.
Pancreatic Neoplasms
Dehydroepiandrosterone modulates oxidative DNA damage in pancreatic cancer: A case-control study.
Paralysis
DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies.
Parasitemia
Human resistance to Plasmodium falciparum increases during puberty and is predicted by dehydroepiandrosterone sulfate levels.
Parkinsonian Disorders
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Pemphigus
Evaluating serum prolactin and serum dehydroepiandrosterone sulfate levels in patients with pemphigus.
Periodontitis
Association of cortisol and dehydroepiandrosterone sulphate levels in serum with periodontal status in older Japanese adults.
Periventricular Nodular Heterotopia
Steroid Sulfatase Deficiency With Bilateral Periventricular Nodular Heterotopia.
Pheochromocytoma
Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins.
Laparoscopic adrenalectomy. The importance of a flank approach in the lateral decubitus position.
Pituitary ACTH Hypersecretion
Cushing's syndrome: new variants and association with empty sella syndrome.
Dissociation of adrenal androgen and cortisol secretion in Cushing's syndrome.
Prostate-specific antigen is increased in female patients with Cushing's disease.
Reduced serum levels of dehydroepiandrosterone sulphate in adrenal incidentalomas: a marker of adrenocortical tumour.
Pityriasis
Pityriasis rotunda with low levels of steroid sulfatase.
Polycystic Ovary Syndrome
AMH MEASUREMENT VERSUS OVARIAN ULTRASOUND IN THE DIAGNOSIS OF POLYCYSTIC OVARY SYNDROME IN DIFFERENT PHENOTYPES.
Association of Luteinizing hormone and LH receptor gene polymorphism with susceptibility of Polycystic ovary syndrome.
Dehydroepiandrosterone Sulfate (DHEAS) Levels in Polycystic Ovarian Syndrome (PCOS).
Dehydroepiandrosterone sulfate and insulin resistance in patients with polycystic ovary syndrome.
Development of a method for the measurement of dehydroepiandrosterone sulphate by liquid chromatography-tandem mass spectrometry.
Effect of insulin and testosterone on androgen production and transcription of SULT2A1 in the NCI-h295r adrenocortical cell line.
Influence of adrenal hyperandrogenism on the clinical and metabolic phenotype of women with polycystic ovary syndrome.
PAPSS2 deficiency causes androgen excess via impaired DHEA sulfation - in vitro and in vivo studies in a family harboring two novel PAPSS2 mutations.
Placental steroidogenesis in pregnant women with polycystic ovary syndrome.
Premature Adrenarche and its Association with Cardiovascular Risk in Females.
Prevalence and metabolic characteristics of adrenal androgen excess in hyperandrogenic women with different phenotypes.
Prevalence of hyperandrogenemia in the polycystic ovary syndrome diagnosed by the National Institutes of Health 1990 criteria.
Role of a CYP17 polymorphism in the regulation of circulating dehydroepiandrosterone sulfate levels in women with polycystic ovary syndrome.
THE RARE CASE OF MIXED GONADAL DYSGENESIS, MOSAIC KARYOTYPE, PETROCLIVAL MENINGIOMA AND IDIOPATHIC HYPERDEHYDROEPIANDROSTERONISM.
Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome.
Use of dexamethasone and clomiphene citrate in the treatment of clomiphene citrate-resistant patients with polycystic ovary syndrome and normal dehydroepiandrosterone sulfate levels: a prospective, double-blind, placebo-controlled trial.
Variants in SULT2A1 Affect the DHEA Sulphate to DHEA Ratio in Patients With Polycystic Ovary Syndrome But Not the Hyperandrogenic Phenotype.
Visceral adiposity index and DHEAS are useful markers of diabetes risk in women with polycystic ovary syndrome.
Polycythemia
Aromatase activity after a short-course of letrozole administration in adult men at sea level and at high altitude (with or without excessive erythrocytosis).
Polymicrogyria
Banding pattern on polarized hair microscopic examination and unilateral polymicrogyria in a patient with steroid sulfatase deficiency.
Polymyalgia Rheumatica
Hypothalamic-pituitary-adrenal axis impairment in the pathogenesis of rheumatoid arthritis and polymyalgia rheumatica.
Low serum levels of DHEAS in untreated polymyalgia rheumatica/giant cell arteritis.
Pre-Eclampsia
Concentrations of corticotrophin-releasing hormone in the umbilical-cord blood of pregnancies complicated by pre-eclampsia.
Early second-trimester maternal hyperandrogenemia and subsequent preeclampsia: a prospective study.
Levels of sex steroid hormones and their receptors in women with preeclampsia.
Maternal Preeclampsia and Androgens in the Offspring around Puberty: A Follow-Up Study.
Progesterone and estradiol production by normal and preeclamptic placentas.
Stable prolactin level after enhanced estradiol production following dehydroepiandrosterone sulfate.
Steroid sulfatase is increased in the placentas and whole blood of women with early-onset preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Association between dehydroepiandrosterone-sulfate and attention in long-term survivors of childhood acute lymphoblastic leukemia treated with only chemotherapy.
Primary Ovarian Insufficiency
Adrenarche and pubarche in girls with turner syndrome during growth-promoting therapy with human growth hormone.
The importance of adrenal hypoandrogenism in infertile women with low functional ovarian reserve: a case study of associated adrenal insufficiency.
Prostatic Diseases
Role of OATP transporters in steroid uptake by prostate cancer cells in vivo.
Prostatic Hyperplasia
Cross-sectional analysis between prostate volumes and serum sex hormones in Japanese men attending a urological clinic.
Prostatic Neoplasms
6-[2-(adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases.
Bacterial Lipopolysaccharides Induce Steroid Sulfatase Expression and Cell Migration through IL-6 Pathway in Human Prostate Cancer Cells.
Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.
Differential metabolism of dehydroepiandrosterone sulfate and estrogen conjugates by normal or malignant AXC/SSh rat prostate cells and effects of these steroid conjugates on cancer cell proliferation in vitro.
Do differences in age specific androgenic steroid hormone levels account for differing prostate cancer rates between Arabs and Caucasians?
Induction of steroid sulfatase expression by tumor necrosis factor-? through phosphatidylinositol 3-kinase/Akt signaling pathway in PC-3 human prostate cancer cells.
Induction of steroid sulfatase expression in PC-3 human prostate cancer cells by insulin-like growth factor II.
Influence of Statins on Survival Outcome in Patients with Metastatic Castration Resistant Prostate Cancer Treated with Abiraterone Acetate.
Prostate cancer risk: the significance of differences in age related changes in serum conjugated and unconjugated steroid hormone concentrations between arab and caucasian men.
Statin Use at the Time of Initiation of Androgen Deprivation Therapy and Time to Progression in Patients With Hormone-Sensitive Prostate Cancer.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer.
Steroid sulfatase stimulates intracrine androgen synthesis and is a therapeutic target for advanced prostate cancer.
The endocrine profiles in men with localized and locally advanced prostate cancer treated with radical prostatectomy.
V89L polymorphism of the 5alpha-reductase Type II gene (SRD5A2), endogenous sex hormones, and prostate cancer risk.
Proteinuria
[High androgen plasmatic levels in women affected with pregnancy-induced hypertension]
Psoriasis
Blood dehydroepiandrosterone sulphate (DHEAS) levels in pemphigoid/pemphigus and psoriasis.
Puberty, Delayed
X-linked ichthyosis with hypogonadism: not always Kallmann's syndrome.
Puberty, Precocious
[Psychological behavior of girls with idiopathic central precocious puberty before and after treatment with gonadotropin-releasing hormone analogue]
[Relationship between serum dehydroepiandrosterone levels and female precocious puberty]
Pulmonary Disease, Chronic Obstructive
Dehydroepiandrosterone-sulfate serum levels and common age-related diseases: results from a cross-sectional Italian study of a general elderly population.
Estrogen Activation by Steroid Sulfatase increases Colorectal Cancer proliferation via GPER.
Increased levels of enzymes involved in local estradiol synthesis in chronic obstructive pulmonary disease.
Sex hormone alterations and systemic inflammation in chronic obstructive pulmonary disease.
Retroviridae Infections
Dehydroepiandrosterone (DHEA) sulfate prevents reduction in tissue vitamin E and increased lipid peroxidation due to murine retrovirus infection of aged mice.
Immune dysfunction during alcohol consumption and murine AIDS: the protective role of dehydroepiandrosterone sulfate.
Modulation of immune dysfunction during murine leukaemia retrovirus infection of old mice by dehydroepiandrosterone sulphate (DHEAS).
Rheumatic Diseases
Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.
Rhinitis, Allergic
Allergic disease as an association of steroid sulphatase deficiency.
Sarcopenia
Effect of DHEAS on skeletal muscle over the life span: the InCHIANTI study.
Sex hormones and sarcopenia in older persons.
Schistosomiasis mansoni
The relationships between dehydroepiandrosterone sulphate (DHEAS), the intensity of Schistosoma mansoni infection and parasite-specific antibody responses. A cross-sectional study in residents of endemic communities in north-east Ethiopia.
Scleroderma, Systemic
High prolactin and low dehydroepiandrosterone sulphate serum levels in patients with severe systemic sclerosis.
Seizures
Banding pattern on polarized hair microscopic examination and unilateral polymicrogyria in a patient with steroid sulfatase deficiency.
Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsy.
Effects of acute and chronic administration of neurosteroid dehydroepiandrosterone sulfate on neuronal excitability in mice.
Mean daily plasma concentrations of beta-endorphin, leu-enkephalin, ACTH, cortisol, and DHEAS in epileptic patients with complex partial seizures evolving to generalized tonic-clonic seizures.
Seizure frequency and cortisol and dehydroepiandrosterone sulfate (DHEAS) levels in women with epilepsy receiving antiepileptic drug treatment.
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol.
Sepsis
Adrenal androgens and the immune system.
Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?
Dehydroepiandrosterone sulfate and dehydroepiandrosterone sulfate/cortisol ratio in cirrhotic patients with septic shock: another sign of hepatoadrenal syndrome?
Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock.
Sertoli Cell-Only Syndrome
Testicular steroid sulfatase overexpression is associated with Leydig cell dysfunction in primary spermatogenic failure.
Shock, Septic
Decreased levels of dehydroepiandrosterone sulphate in severe critical illness: a sign of exhausted adrenal reserve?
Dehydroepiandrosterone sulfate and dehydroepiandrosterone sulfate/cortisol ratio in cirrhotic patients with septic shock: another sign of hepatoadrenal syndrome?
Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock.
Skin Diseases
6-[2-(adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases.
Review: genetics of steroid sulphatase deficiency and X-linked ichthyosis.
Skin Neoplasms
Serum dehydroepiandrosterone and dehydroepiandrosterone sulfate and risk of melanoma or squamous cell carcinoma of the skin.
Smith-Lemli-Opitz Syndrome
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Are low maternal estriol levels a predictor for pro-opiomelanocortin (POMC) deficiency caused by POMC mutation during pregnancy?
Low estriol levels in the maternal triple-marker screen as a predictor of isolated adrenocorticotropic hormone deficiency caused by a new mutation in the TPIT gene.
Maternal serum unconjugated estriol as a predictor for Smith-Lemli-Opitz syndrome and other fetal conditions.
Prevalence of steroid sulfatase deficiency in California according to race and ethnicity.
Solitary Kidney
Hypogonadotrophic hypogonadism with hyposmia, X-linked ichthyosis, and renal malformation syndrome.
Spinal Cord Injuries
Astrocyte Neuroprotection and Dehydroepiandrosterone.
Spinal Cord Ischemia
Dehydroepiandrosterone sulfate is neuroprotective in a reversible spinal cord ischemia model: possible involvement of GABA(A) receptors.
Starvation
Aromatase inhibitors and other novel agents in breast cancer treatment.
steroid 21-monooxygenase deficiency
Disproportionate suppression of dehydroepiandrosterone sulfate (DHEAS) in treated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
[Screening for congenital adrenal hyperplasia in pregnancy: results and perspectives].
steryl-sulfatase deficiency
3 beta-Hydroxysteroid dehydrogenase-isomerase activity in placentae from pregnancies complicated by steroid sulphatase deficiency.
: Recognising placental steroid sulphatase deficiency.
A new method for the determination of steroid sulphatase activity in leukocytes in X-linked recessive ichthyosis.
Abnormal androgen and oestrogen metabolism in men with steroid sulphatase deficiency and recessive X-linked ichthyosis.
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Allergic disease as an association of steroid sulphatase deficiency.
Anabolic deficiencies in men with systolic heart failure: do co-morbidities and therapies really contribute significantly?
Antenatal detection of placental steroid sulphatase deficiency by measurement of urinary 16 alpha-hydroxydehydroepiandrosterone sulphate.
Antenatal detection of placental steroid sulphatase deficiency: use of a dehydroepiandrosterone sulphate loading test.
Antenatal diagnosis of steroid sulphatase deficiency: case report and literature survey.
Are low maternal estriol levels a predictor for pro-opiomelanocortin (POMC) deficiency caused by POMC mutation during pregnancy?
Association of dehydroepiandrosterone sulfate and testosterone deficiency with bone turnover in men with inflammatory bowel disease.
Association of undetectable unconjugated estriol on multiple marker screening with steroid sulfatase deficiency.
Banding pattern on polarized hair microscopic examination and unilateral polymicrogyria in a patient with steroid sulfatase deficiency.
Blood dehydroepiandrosterone sulphate (DHEAS) levels in pemphigoid/pemphigus and psoriasis.
Carrier identification in steroid sulphatase deficiency and recessive X-linked ichthyosis.
Characterization of a low copy repetitive element S232 involved in the generation of frequent deletions of the distal short arm of the human X chromosome.
Characterization of low-density lipoproteins from patients with recessive X-linked ichthyosis.
Characterization of the deletion breakpoints in a patient with steroid sulfatase deficiency.
Clinical pathologic correlation of superficial corneal opacities in X-linked ichthyosis.
Clinical spectrum of steroid sulfatase deficiency: X-linked recessive ichthyosis, birth complications and cryptorchidism.
Congenital hypopituitarism as a cause of undetectable estriol levels in the maternal triple-marker screen.
Contiguous gene syndromes due to deletions in the distal short arm of the human X chromosome.
Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis.
Deficiencies in circulating testosterone and dehydroepiandrosterone sulphate, and depression in men with systolic chronic heart failure.
Deletion analysis maps ocular albinism proximal to the steroid sulphatase locus.
Deletion of exons 1-5 of the STS gene causing X-linked ichthyosis.
Deletion of the distal short arm of the X chromosome (Xp) in a patient with short stature, chondrodysplasia punctata, and X-linked ichthyosis due to steroid sulfatase deficiency.
Deletion pattern of the STS gene in X-linked ichthyosis in a Mexican population.
Determination of cholesteryl sulphate by isotope dilution-mass spectrometry for diagnosis of steroid sulphatase deficiency.
DHEAS deficiency during consumption of sustained-action prescribed opioids: evidence for opioid-induced inhibition of adrenal androgen production.
Does steroid sulfatase deficiency influence postpartum psychosis risk?
Dosage of the Sts gene in the mouse.
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.
Enzymatic diagnosis of steroid sulfatase deficiency by high performance liquid chromatography.
Familial X-linked ichthyosis, steroid sulfatase deficiency, mental retardation, and nullisomy for Xp223-pter.
Foetal steroid sulphatase deficiency. A case report.
Four cases of pregnancy with low estrogen production due to placental enzymatic deficiency.
Frequency of steroid sulfatase deficiency in Hiroshima.
Frequent deletions of the human X chromosome distal short arm result from recombination between low copy repetitive elements.
Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase.
Gonadal and adrenal androgen deficiencies as independent predictors of increased cardiovascular mortality in men with type II diabetes mellitus and stable coronary artery disease.
Hair root analysis in X-linked ichthyosis.
Heterozygote detection in steroid sulphatase deficiency.
High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency.
Human placental steryl-sulfatase. Enzyme purification, production of antisera, and immunoblotting reactions with normal and sulfatase-deficient placentas.
Human steroid sulphatase deficiency.
Hydrolysis of deoxycorticosterone-21-yl sulphate and dehydroepiandrosterone sulphate by microsomal preparations of human placentae: evidence for a common enzyme.
Ichthyosis of steroid sulphatase deficiency. Clinical study of 76 cases.
Ichthyosis. Reliability of clinical signs in the differentiation between autosomal dominant and sex-linked forms.
Ichthyosis: the skin manifestation of multiple sulfatase deficiency.
Increased cholesterol sulfate in plasma and red blood cell membranes of steroid sulfatase deficient patients.
Lactation in placental steroid sulphatase deficiency.
Lipoprotein electrophoresis in recessive X-linked ichthyosis.
Low maternal serum unconjugated estriol during prenatal screening as an indication of placental steroid sulfatase deficiency and X-linked ichthyosis.
Low or absent unconjugated estriol in pregnancy: an indicator for steroid sulfatase deficiency detectable by fluorescence in situ hybridization and biochemical analysis.
Maternal serum unconjugated estriol as a predictor for Smith-Lemli-Opitz syndrome and other fetal conditions.
Maternal steroid sulfatase deficiency--cause of high-risk pregnancy?
Maternal transmission of the 3 bp deletion within exon 7 of the STS gene in steroid sulfatase deficiency.
Maternal urine and serum steroid measurements to identify steroid sulfatase deficiency (STSD) in second trimester pregnancies.
Metabolism of 3H-dehydroepiandrosterone sulphate by subjects with steroid sulphatase deficiency.
Mild ichthyosis in a 4-year-old boy with multiple sulphatase deficiency.
Molecular heterogeneity of steroid sulfatase deficiency: a multicenter study on 57 unrelated patients, at DNA and protein levels.
More on X-linked ichthyosis, steroid sulfatase deficiency, and hypogonadism and anosmia.
Multipoint linkage analysis of steroid sulfatase (X-linked ichthyosis) and distal Xp markers.
Mutation report: a novel partial deletion of exons 2-10 of the STS gene in recessive X-linked ichthyosis.
Nonsyndromic types of ichthyoses - an update.
Novel point mutations in the steroid sulfatase gene in patients with X-linked ichthyosis: transfection analysis using the mutated genes.
Ocular findings in X-linked ichthyosis: a survey on 38 cases.
Placental steroid deficiency: association with arylsulfatase A deficiency.
Placental steroid sulfatase deficiency.
Placental steroid sulfatase deficiency: biochemical diagnosis and clinical review.
Placental steroid sulphatase deficiency.
Placental steroid sulphatase deficiency: an approach to antenatal care and delivery.
Placental sulfatase deficiency: maternal and fetal expression of steroid sulfatase deficiency and X-linked ichthyosis.
Prenatal detection of X-linked ichthyosis by maternal serum screening for Down syndrome.
Prenatal diagnosis of placental steroid sulfatase deficiency.
Prenatal diagnosis of sex differentiation disorders: the role of fetal ultrasound.
Prenatal diagnosis of X-linked ichthyosis using molecular cytogenetics.
Prenatal diagnosis of X-linked ichthyosis.
Prevalence of steroid sulfatase deficiency in California according to race and ethnicity.
Recognising placental steroid sulphatase deficiency.
Recurrent bilateral corneal erosions due to an association of epidermolysis bullosa simplex Köbner and X-linked ichthyosis with steroid sulfatase deficiency.
Regional assignment of the gene locus for steroid sulfatase.
Regulation of serum testosterone in men with steroid sulfatase deficiency: response to human chorionic gonadotropin.
Replacement therapy with DHEA plus corticosteroids in patients with chronic inflammatory diseases--substitutes of adrenal and sex hormones.
Reversion of aging-related DHEAS decline in mouse plasma alleviates aging-related glucose tolerance impairment by potentiation of glucose-stimulated insulin secretion of acute phase.
Review: genetics of steroid sulphatase deficiency and X-linked ichthyosis.
Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency.
Role of the pseudoautosomal region in sex-chromosome pairing during male meiosis: meiotic studies in a man with a deletion of distal Xp.
Second-trimester maternal serum screening using alpha-fetoprotein, human chorionic gonadotrophin, and unconjugated oestriol: experience of a regional programme.
Sequence analysis of a partial deletion of the human steroid sulfatase gene reveals 3 bp of homology at deletion breakpoints.
Serum dehydroepiandrosterone sulfate, testosterone, and biochemical markers of bone turnover in elderly Thai men.
Serum steroid sulphates in ichthyosis.
Sex-linked ichthyosis and placental sulphatase C deficiency.
Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS.
Somatic and germinal mosaicism for the steroid sulfatase gene deletion in a steroid sulfatase deficiency carrier.
Steroid sulfatase activity in human leukocytes.
Steroid sulfatase activity in leukocytes: a comparative study in 45,X; 46,Xi(Xq) and carriers of steroid sulfatase deficiency.
Steroid sulfatase deficiency and contiguous gene deletion syndrome amongst pregnant patients with low serum unconjugated estriols.
Steroid sulfatase deficiency and the genetics of the short arm of the human X chromosome.
Steroid sulfatase deficiency and X-linked ichthyosis.
Steroid sulfatase deficiency in Japanese patients: characterization of X-linked ichthyosis by using polymerase chain reaction.
Steroid Sulfatase Deficiency With Bilateral Periventricular Nodular Heterotopia.
Steroid sulfatase deficiency.
Steroid sulfatase deficiency: enzymatic studies using placenta and leucocytes in one family.
Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder.
Steroid sulphatase deficiency and hypogonadism.
Steroid sulphatase deficiency associated with testis cancer.
Steroid sulphatase deficiency disease.
Steroid sulphatase deficiency in patients initially diagnosed as ichthyosis vulgaris or recessive X-linked ichthyosis.
Steroid sulphatase deficiency is present in patients with the syndrome 'ichthyosis and male hypogonadism' and with 'Rud syndrome'.
Steroid sulphatase deficiency is the major cause of extremely low oestriol production at mid-pregnancy: a urinary steroid assay for the discrimination of steroid sulphatase deficiency from other causes.
Steroid sulphatase deficiency.
Steroid sulphatase deficiency. Steroid sulphatase and arylsulphatase C determination in normal and affected fibroblasts.
Steroid sulphatase deficiency: identification of heterozygotes using hydrolysis of dehydroepiandrosterone sulphate by peripheral leucocytes.
Steroid-resistant nephrotic syndrome associated with steroid sulfatase deficiency-x-linked recessive ichthyosis: a case report and review of literature.
Studies of the biochemical basis of steroid sulphatase deficiency--III. Phospholipid composition of microsomes from normal and steroid sulphatase deficient placentas.
Studies of the biochemical basis of steroid sulphatase deficiency: preliminary evidence suggesting a defect in membrane-enzyme structure.
Studies on cross-reacting material to steroid sulphatase in fibroblasts from patients affected by different types of steroid sulphatase deficiency.
Submicroscopic Xpter deletion in a boy with growth and mental retardation caused by a familial t(X;14).
The human arylsulfatase-C isoenzymes: two distinct genes that escape from X inactivation.
The nature of placental steroid sulphatase deficiency in man.
The role of antenatal oestrogen in post-partum human lactogenesis: evidence from oestrogen-deficient pregnancies.
Two cases of steroid sulfatase deficiency with complex phenotype due to contiguous gene deletions.
Unconjugated estriol as an indication for prenatal diagnosis of steroid sulfatase deficiency by in situ hybridization.
Urinary excretion of oestrone, oestradiol-17 beta and oestriol in pregnancies complicated by steroid sulphatase deficiency.
Very low maternal serum unconjugated estriol and prenatal diagnosis of steroid sulfatase deficiency.
X chromosome deletions detectable by flow cytometry in some patients with steroid sulphatase deficiency (X-linked ichthyosis).
X-chromosome inactivation: role in skin disease expression.
X-linked ichthyosis and X-linked placental sulfatase deficiency: a disease entity. Histochemical observations.
X-linked ichthyosis due to steroid sulfatase deficiency associated with hypogonadism and anosmia.
X-linked ichthyosis with hypogonadism: not always Kallmann's syndrome.
X-linked ichthyosis, due to steroid sulphatase deficiency, associated with Kallmann syndrome (hypogonadotropic hypogonadism and anosmia): linkage relationships with Xg and cloned DNA sequences from the distal short arm of the X chromosome.
X-linked ichthyosis: relation between cholesterol sulphate, dehydroepiandrosterone sulphate and patient's age.
X-linked recessive ichthyosis. Enzymatic diagnosis of affected males and female carriers.
[A Case of Steroid Sulfatase Deficiency Complicated by Bilateral Undescended Testis].
[Arylsulfatase C deficiency in leukocytes in patients and carrier of X-chromosome recessive ichthyosis]
[Biochemical study on steroid sulfatase and its clinical application to the obstetrics and gynecology]
[Genetic analysis of a rare case with Kallman syndrome and steroid sulfatase deficiency].
[Ichthyosis X. Clinical review and rapid identification using lipid electrophoresis]
[Identification of gene mutation and prenatal diagnosis in a family with X-linked ichthyosis].
[Occurrence of X-linked ichthyosis along with atopy]
[Placental steroid sulfatase deficiency. Reduced estriol production]
[Steroid sulfatase and placental deficiency. Current data as instigators of new research]
[Steroid sulphatase deficiency]
[Two cases of X-linked ichthyosis associated with myopathies]
Stroke
Are low dehydroepiandrosterone sulphate levels predictive for cardiovascular diseases? A review of prospective and retrospective studies.
Dehydroepiandrosterone sulfate, incidence of myocardial infarction, and extent of atherosclerosis in men.
sulfate adenylyltransferase deficiency
Low DHEAS Concentration in a Girl Presenting with Short Stature and Premature Pubarche: A Novel PAPSS2 Gene Mutation.
Testicular Diseases
Absence of testicular steroid sulphatase activity in a boy with recessive X-linked ichthyosis and testicular maldescent.
Testicular Neoplasms
Lack of an association between testicular cancers and low steroid sulphatase activity in peripheral leucocytes.
Steroid sulphatase deficiency associated with testis cancer.
Tetanus
DHEAS as an effective vaccine adjuvant in elderly humans. Proof-of-principle studies.
Thalassemia
Evaluation of the glucocorticoid, mineralocorticoid, and adrenal androgen secretion dynamics in a large cohort of patients aged 6-18 years with transfusion-dependent ?-thalassemia major, with an emphasis on the impact of cardiac iron load.
Thyroid Nodule
Decreased serum IGF-I and dehydroepiandrosterone sulphate may be risk factors for the development of reduced bone mass in postmenopausal women with endogenous subclinical hyperthyroidism.
Thyroiditis, Autoimmune
Dehydroepiandrosterone sulfate does not prevent spontaneous and iodine-induced lymphocytic thyroiditis and diabetes mellitus in the BB/Wor rat.
Thyrotoxicosis
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Toxoplasmosis, Ocular
Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis.
Trisomy 13 Syndrome
Second-trimester maternal serum screening using alpha-fetoprotein, human chorionic gonadotrophin, and unconjugated oestriol: experience of a regional programme.
Trisomy 18 Syndrome
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Second-trimester maternal serum screening using alpha-fetoprotein, human chorionic gonadotrophin, and unconjugated oestriol: experience of a regional programme.
Tuberculosis
Dehydroepiandrosterone sulphate enhances IgG and Interferon-gamma production during immunization to tuberculosis in young but not aged mice.
The endocrinology of adrenal tuberculosis: the effects of tuberculosis on the hypothalamo-pituitary-adrenal axis and adrenocortical function.
Turner Syndrome
Advances in prenatal screening for Down syndrome: I. general principles and second trimester testing.
Effect of Dosage of 17ß-Estradiol on Uterine Growth in Turner Syndrome-A Randomized Controlled Clinical Pilot Trial.
Reduced androgen levels in adult turner syndrome: influence of female sex steroids and growth hormone status.
The early dehydroepiandrosterone sulfate rise of adrenarche and the delay of pubarche indicate primary ovarian failure in Turner syndrome.
Urinary Bladder Neoplasms
Steroid sulfatase promotes invasion through epithelial-mesenchymal transition and predicts the progression of bladder cancer.
Uterine Cervical Neoplasms
Estrogen formation in endometrial and cervix cancer cell lines: Involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12).
Human steroid sulfatase induces Wnt/?-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1? in human prostate and cervical cancer cells.
Induction of Integrin Signaling by Steroid Sulfatase in Human Cervical Cancer Cells.
Vascular Diseases
Dehydroepiandrosterone sulfate, diseases and mortality in a general aged population.
Effects of dehydroepiandrosterone sulfate on cellular calcium responsiveness and vascular contractility.
Vascular System Injuries
Adrenal androgen dehydroepiandrosterone sulfate inhibits vascular remodeling following arterial injury.
Vertigo
Effects of the neurosteroid dehydroepiandrosterone sulfate on medial vestibular nucleus neurons.
Vitiligo
Association of serum cortisol and dehydroepiandrosterone sulfate (DHEAS) levels with psychological stress in patients with vitiligo
Whooping Cough
Metabotropic neurosteroid/sigma-receptor involved in stimulation of nociceptor endings of mice.
Wilms Tumor
New frontiers on the molecular underpinnings of hypospadias according to severity.