Disease on EC 3.1.6.14 - N-acetylglucosamine-6-sulfatase
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arylsulfatase (type i) deficiency
A screening method for mucopolysaccharidoses with increased urinary excretion of sulfated N-acetylhexosamines.
Carcinoma, Ductal
Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma.
Carcinoma, Hepatocellular
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo.
Carcinoma, Intraductal, Noninfiltrating
Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma.
Liver Neoplasms
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo.
Liver Neoplasms
Sulfatase-1 knockdown promotes in vitro and in vivo aggressive behavior of murine hepatocarcinoma Hca-P cells through up-regulation of mesothelin.
Lung Neoplasms
MicroRNA-527 inhibits TGF-?/SMAD induced epithelial-mesenchymal transition via downregulating SULF2 expression in non-small-cell lung cancer.
Lymphatic Metastasis
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo.
Lymphatic Metastasis
Upregulation of sulfatase-1 decreases metastatic potential of SKOV3 human ovarian cancer cells in vitro and in vivo.
Lysosomal Storage Diseases
Caprine mucopolysaccharidosis IIID: fetal and neonatal brain and liver glycosaminoglycan and morphological perturbations.
Lysosomal Storage Diseases
Mucopolysaccharidosis III (Sanfilippo Syndrome)- disease presentation and experimental therapies.
Lysosomal Storage Diseases
Update of the spectrum of mucopolysaccharidoses type III in Tunisia: identification of three novel mutations and in silico structural analysis of the missense mutations.
Mucopolysaccharidoses
Caprine mucopolysaccharidosis IIID: a preliminary trial of enzyme replacement therapy.
Mucopolysaccharidoses
Caprine mucopolysaccharidosis IIID: fetal and neonatal brain and liver glycosaminoglycan and morphological perturbations.
Mucopolysaccharidoses
Diagnosis of caprine mucopolysaccharidosis type IIID by real-time polymerase chain reaction-based genotyping.
Mucopolysaccharidoses
Genomic basis of mucopolysaccharidosis type IIID (MIM 252940) revealed by sequencing of GNS encoding N-acetylglucosamine-6-sulfatase.
Mucopolysaccharidoses
Human glucosamine-6-sulfatase cDNA reveals homology with steroid sulfatase.
Mucopolysaccharidoses
Mucopolysaccharidosis III (Sanfilippo Syndrome)- disease presentation and experimental therapies.
Mucopolysaccharidoses
Sanfilippo D syndrome: estimation of N-acetylglucosamine-6-sulfatase activity with a radiolabeled monosulfated disaccharide substrate.
Mucopolysaccharidoses
Sanfilippo syndrome type D: natural history and identification of 3 novel mutations in the GNS Gene.
Mucopolysaccharidoses
Update of the spectrum of mucopolysaccharidoses type III in Tunisia: identification of three novel mutations and in silico structural analysis of the missense mutations.
Mucopolysaccharidosis III
A screening method for mucopolysaccharidoses with increased urinary excretion of sulfated N-acetylhexosamines.
Mucopolysaccharidosis III
Caprine mucopolysaccharidosis IIID: a preliminary trial of enzyme replacement therapy.
Mucopolysaccharidosis III
Diagnosis of caprine mucopolysaccharidosis type IIID by real-time polymerase chain reaction-based genotyping.
Mucopolysaccharidosis III
Genomic basis of mucopolysaccharidosis type IIID (MIM 252940) revealed by sequencing of GNS encoding N-acetylglucosamine-6-sulfatase.
Mucopolysaccharidosis III
Human glucosamine-6-sulfatase cDNA reveals homology with steroid sulfatase.
Mucopolysaccharidosis III
Molecular characterization of MPS IIIA, MPS IIIB and MPS IIIC in Tunisian patients.
Mucopolysaccharidosis III
Mucopolysaccharidosis III (Sanfilippo Syndrome)- disease presentation and experimental therapies.
Mucopolysaccharidosis III
Recombinant caprine 3H-[N-acetylglucosamine-6-sulfatase] and human 3H-[N-acetylgalactosamine-4-sulfatase]: plasma clearance, tissue distribution, and cellular uptake in the rat.
Mucopolysaccharidosis III
Sanfilippo D syndrome: estimation of N-acetylglucosamine-6-sulfatase activity with a radiolabeled monosulfated disaccharide substrate.
Mucopolysaccharidosis III
Sanfilippo syndrome type D: natural history and identification of 3 novel mutations in the GNS Gene.
Mucopolysaccharidosis III
Sanfilippo syndrome, type D: a spectrophotometric assay with prenatal diagnostic potential.
Multiple Sulfatase Deficiency Disease
A screening method for mucopolysaccharidoses with increased urinary excretion of sulfated N-acetylhexosamines.
Neoplasm Metastasis
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo.
Neoplasm Metastasis
SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.
Neoplasm Metastasis
Sulfatase-1 knockdown promotes in vitro and in vivo aggressive behavior of murine hepatocarcinoma Hca-P cells through up-regulation of mesothelin.
Neoplasm Metastasis
Upregulation of sulfatase-1 decreases metastatic potential of SKOV3 human ovarian cancer cells in vitro and in vivo.
Neoplasms
Identification and characterization of unique tumoricidal genes in rat umbilical cord matrix stem cells.
Neoplasms
Identification of SULF2 as a novel transcriptional target of p53 by use of integrated genomic analyses.
Neoplasms
Over expression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivo.
Neoplasms
SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.
Neoplasms
Sulfatase-1 knockdown promotes in vitro and in vivo aggressive behavior of murine hepatocarcinoma Hca-P cells through up-regulation of mesothelin.
Osteoarthritis
Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.
Osteoarthritis
Suppression of cartilage degeneration by intra-articular injection of heparan sulfate 6-O endosulfatase in a mouse osteoarthritis model.
Osteoarthritis, Knee
Suppression of cartilage degeneration by intra-articular injection of heparan sulfate 6-O endosulfatase in a mouse osteoarthritis model.
Ovarian Neoplasms
Upregulation of sulfatase-1 decreases metastatic potential of SKOV3 human ovarian cancer cells in vitro and in vivo.
Pneumonia
Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.
Stomach Neoplasms
Endo-sulfatase Sulf-1 protein expression is down-regulated in gastric cancer.
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