Reference on EC 3.1.4.53 - 3',5'-cyclic-AMP phosphodiesterase and Organism(s) Rattus norvegicus and UniProt Accession P14270
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tanaka, S.; Shimooka, S.; Shimomura, H.
Changes in phosphodiesterase activity in the developing rat submandibular gland
Arch. Oral Biol.
47
567-576
2002
Rattus norvegicus
Giorgi, M.; Modica, A.; Pompili, A.; Pacitti, C.; Gasbarri, A.
The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task
Behav. Brain Res.
154
99-106
2004
Rattus norvegicus
Keravis, T.; Thaseldar-Roumie, R.; Lugnier, C.
Assessment of phosphodiesterase isozyme contribution in cell and tissue extracts
Methods Mol. Biol.
307
63-74
2005
Rattus norvegicus
Levallet, G.; Levallet, J.; Bouraima-Lelong, H.; Bonnamy, P.J.
Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated PDE4 activities in immature rat sertoli cells
Biol. Reprod.
76
794-803
2007
Rattus norvegicus
Fougier, S.; Nemoz, G.; Prigent, A.F.; Marivet, M.; Bourguignon, J.J.; Wermuth, C.; Pacheco, H.
Purification of cAMP-specific phosphodiesterase from rat heart by affinity chromatography on immobilized rolipram
Biochem. Biophys. Res. Commun.
138
205-214
1986
Rattus norvegicus
Pooley, L.; Shakur, Y.; Rena, G.; Houslay, M.D.
Intracellular localization of the PDE4A cAMP-specific phosphodiesterase splice variant RD1 (RNPDE4A1A) in stably transfected human thyroid carcinoma FTC cell lines
Biochem. J.
321 (Pt 1)
177-185
1997
Rattus norvegicus (P54748)
Shepherd, M.; McSorley, T.; Olsen, A.E.; Johnston, L.A.; Thomson, N.C.; Baillie, G.S.; Houslay, M.D.; Bolger, G.B.
Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform
Biochem. J.
370
429-438
2003
Rattus norvegicus (P14646)
Bian, H.; Zhang, J.; Wu, P.; Lori, A.; Varty, Y.J.; Maywood, T.; Hey, J.A.; Wang, P.
Differential type 4 cAMP-specific phosphodiesterase (PDE4) expression and functional sensitivity to PDE4 inhibitors among rats, monkeys and humans
Biochem. Pharmacol.
68
2229-2236
2004
Rattus norvegicus (P14270), Rattus norvegicus (P14646), Rattus norvegicus (P54748), Homo sapiens (P27815), Homo sapiens (Q07343), Homo sapiens (Q08493), Homo sapiens (Q08499), Homo sapiens
Kovala, T.; Sanwal, B.D.; Ball, E.H.
Recombinant expression of a type IV, cAMP-specific phosphodiesterase: Characterization and structure-function studies of deletion mutants
Biochemistry
36
2968-2976
1997
Rattus norvegicus
Bolger, G.B.; Peden, A.H.; Steele, M.R.; MacKenzie, C.; McEwan, D.G.; Wallace, D.A.; Huston, E.; Baillie, G.S.; Houslay, M.D.
Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2
J. Biol. Chem.
278
33351-33363
2003
Rattus norvegicus
Huston, E.; Gall, I.; Houslay, T.M.; Houslay, M.D.
Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+
J. Cell Sci.
119
3799-3810
2006
Rattus norvegicus (P54748)
Macovschi, O.; Prigent, A.F.; Nemoz, G.; Pacheco, H.
Effects of an extract of Ginkgo biloba on the 3',5'-cyclic AMP phosphodiesterase activity of the brain of normal and triethyltin-intoxicated rats
J. Neurochem.
49
107-114
1987
Rattus norvegicus
Waddleton, D.; Wu, W.; Feng, Y.; Thompson, C.; Wu, M.; Zhou, Y.P.; Howard, A.; Thornberry, N.; Li, J.; Mancini, J.A.
Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets
Biochem. Pharmacol.
76
884-893
2008
Rattus norvegicus
van Donkelaar, E.L.; Rutten, K.; Blokland, A.; Akkerman, S.; Steinbusch, H.W.; Prickaerts, J.
Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion
Eur. J. Pharmacol.
600
98-104
2008
Rattus norvegicus
Tawar, U.; Kotlo, K.; Jain, S.; Shukla, S.; Setty, S.; Danziger, R.S.
Renal phosphodiesterase 4B is activated in the Dahl salt-sensitive rat
Hypertension
51
762-766
2008
Rattus norvegicus
Bopp, C.; Hofer, S.; Busch, C.; Spoehr, F.; Weigand, M.A.; Martin, E.; Klein, A.
Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats
J. Surg. Res.
150
66-73
2008
Rattus norvegicus
Galindo-Tovar, A.; Vargas, M.L.; Kaumann, A.J.
Phosphodiesterases PDE3 and PDE4 jointly control the inotropic effects but not chronotropic effects of (-)-CGP12177 despite PDE4-evoked sinoatrial bradycardia in rat atrium
Naunyn Schmiedebergs Arch. Pharmacol.
379
379-384
2009
Rattus norvegicus
Dlaboga, D.; Hajjhussein, H.; ODonnell, J.M.
Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B, -4B, and -10A expression in rat striatum
Neuropharmacology
54
745-754
2008
Rattus norvegicus
Miwa, T.; Mori, A.; Nakahara, T.; Ishii, K.
Intravenously administered phosphodiesterase 4 inhibitors dilate retinal blood vessels in rats
Eur. J. Pharmacol.
602
112-116
2009
Rattus norvegicus
Wang, Y.J.; Jiang, Y.L.; Tang, H.F.; Zhao, C.Z.; Chen, J.Q.
Zl-n-91, a selective phosphodiesterase 4 inhibitor, suppresses inflammatory response in a COPD-like rat model
Int. Immunopharmacol.
10
252-258
2010
Rattus norvegicus
Dodge-Kafka, K.L.; Bauman, A.; Mayer, N.; Henson, E.; Heredia, L.; Ahn, J.; McAvoy, T.; Nairn, A.C.; Kapiloff, M.S.
cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3
J. Biol. Chem.
285
11078-11086
2010
Rattus norvegicus
Rock, E.M.; Benzaquen, J.; Limebeer, C.L.; Parker, L.A.
Potential of the rat model of conditioned gaping to detect nausea produced by rolipram, a phosphodiesterase-4 (PDE4) inhibitor
Pharmacol. Biochem. Behav.
91
537-541
2009
Rattus norvegicus
Korkmaz, S.; Maupoil, V.; Sobry, C.; Brunet, C.; Chevalier, S.; Freslon, J.L.
An increased regional blood flow precedes mesenteric inflammation in rats treated by a phosphodiesterase 4 inhibitor
Toxicol. Sci.
107
298-305
2009
Rattus norvegicus
MacKenzie, K.F.; Wallace, D.A.; Hill, E.V.; Anthony, D.F.; Henderson, D.J.; Houslay, D.M.; Arthur, J.S.; Baillie, G.S.; Houslay, M.D.
Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation
Biochem. J.
435
755-769
2011
Rattus norvegicus (P54748)
Nunes, A.R.; Batuca, J.R.; Monteiro, E.C.
Acute hypoxia modifies cAMP levels induced by inhibitors of phosphodiesterase-4 in rat carotid bodies, carotid arteries and superior cervical ganglia
Br. J. Pharmacol.
159
353-361
2010
Rattus norvegicus
Cheng, D.; Ren, J.; Gillespie, D.G.; Mi, Z.; Jackson, E.K.
Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats
Hypertension
56
1096-1101
2010
Rattus norvegicus
Kelly, M.P.; Adamowicz, W.; Bove, S.; Hartman, A.J.; Mariga, A.; Pathak, G.; Reinhart, V.; Romegialli, A.; Kleiman, R.J.
Select 3,5-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain
Cell. Signal.
26
383-397
2014
Mus musculus, Rattus norvegicus
Cai, Y.; Nagel, D.J.; Zhou, Q.; Cygnar, K.D.; Zhao, H.; Li, F.; Pi, X.; Knight, P.A.; Yan, C.
Role of cAMP-phosphodiesterase 1C signaling in regulating growth factor receptor stability, vascular smooth muscle cell growth, migration, and neointimal hyperplasia
Circ. Res.
116
1120-1132
2015
Homo sapiens, Mus musculus, Rattus norvegicus
Guo, L.; Luo, L.; Ju, R.; Chen, C.; Zhu, L.; Li, J.; Yu, X.; Ye, C.; Zhang, D.
Carboxyamidotriazole A novel inhibitor of both cAMP-phosphodiesterases and cGMP-phosphodiesterases
Eur. J. Pharmacol.
746
14-21
2015
Mus musculus, Rattus norvegicus
Ju-Rong, Y.; Ke-Hong, C.; Kun, H.; Bi-Qiong, F.; Li-Rong, L.; Jian-Guo, Z.; Kai-Long, L.; Ya-Ni, H.
Transcription factor Trps1 promotes tubular cell proliferation after ischemia-reperfusion injury through cAMP-specific 3',5'-cyclic phosphodiesterase 4D and AKT
J. Am. Soc. Nephrol.
28
532-544
2017
Rattus norvegicus (P14270)
