Reference on EC 3.1.4.50 - glycosylphosphatidylinositol phospholipase D
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Malik, A.S.; Low, M.G.
Conversion of human placental alkaline phosphatase from a high Mr form to a low Mr form during butanol extraction. An investigation of the role of endogenous phosphoinositide-specific phospholipases
Biochem. J.
240
519-527
1986
Homo sapiens
Low, M.G.; Prasad, A.R.S.
A phospholipase D specific for the phosphatidylinositol anchor of cell-surface proteins is abundant in plasma
Proc. Natl. Acad. Sci. USA
85
980-984
1988
Bos taurus, Canis lupus familiaris, Gallus gallus, Oryctolagus cuniculus, Equus caballus, Homo sapiens, Rattus norvegicus
Stieger, S.; Diem, S.; Jakob, A.; Brodbeck, U.
Enzymatic properties of phosphatidylinositol-glycan-specific phospholipase C from rat liver and phosphatidylinositol-glycan-specific phospholipase D from rat serum [published erratum appears in Eur J Biochem 1991 Sep 15;200(3):812]
Eur. J. Biochem.
197
67-73
1991
Rattus norvegicus
Bowen, R.F.; Raikwar, N.S.; Olson, L.K.; Deeg, M.A.
Glucose and insulin regulate glycosylphosphatidylinositol-specific phospholipase D expression in islet beta cells
Metabolism
50
1489-1492
2001
Mus musculus, Rattus norvegicus
Deeg, M.A.; Davitz, M.A.
Glycosylphosphatidylinositol-phospholipase D: a tool for glycosylphosphatidylinositol structural analysis
Methods Enzymol.
250
630-640
1995
Bos taurus, Homo sapiens
Du, X.; Low, M.G.
Down-regulation of glycosylphosphatidylinositol-specific phospholipase D induced by lipopolysaccharide and oxidative stress in the murine monocyte-macrophage cell line RAW 264.7
Infect. Immun.
69
3214-3223
2001
Mus musculus
Du, X.; Cai, J.; Zhou, J.Z.; Stevens, V.L.; Low, M.G.
Tolerance of glycosylphosphatidylinositol (GPI)-specific phospholipase D overexpression by Chinese hamster ovary cell mutants with aberrant GPI biosynthesis
Biochem. J.
361
113-118
2002
Bos taurus
Hari, T.; Kunze, H.; Bohn, E.; Brodbeck, U.; Butikofer, P.
Subcellular distribution of glycosylphosphatidylinositol-specific phospholipase D in rat liver
Biochem. J.
320
315-319
1996
Rattus norvegicus
Hari, T.; Buetikofer, P.; N.Wiesmann, U.; Brodbeck, U.
Uptake and intracellular stability of glycosylphosphatidylinositol-specific phospholipase D in neuroblastoma cells
Biochim. Biophys. Acta
1355
293-302
1997
Bos taurus
Kueng, M.; Buetikofer, P.; Brodbeck, U.; Stadelmann, B.
Expression of intracellular and GPI-anchored forms of GPI-specific phospholipase D in COS-1 cells
Biochim. Biophys. Acta
1357
329-338
1997
Bos taurus (P80109)
Lee, J.Y.; Kim, M.R.; Sok, D.E.
Enzymatic release of Zn2+-glycerophosphocholine cholinephosphodiesterase from brain membranes by glycosylphosphatidylinositol-specific phospholipases and its regulation
Neurochem. Res.
23
899-905
1998
Bos taurus
Lee, J.Y.; Lee, H.J.; Kim, M.R.; Myung, P.K.; Sok, D.E.
Regulation of brain glycosylphosphatidylinositol-specific phospholipase D by natural amphiphiles
Neurochem. Res.
24
1577-1583
1999
Bos taurus
Li, J.Y.; Hollfelder, K.; Huang, K.S.; Low, M.G.
Structural features of GPI-specific phospholipase D revealed by proteolytic fragmentation and Ca2+ binding studies
J. Biol. Chem.
269
28963-28971
1994
Bos taurus
Maguire, G.A.; Gossner, A.
Glycosyl phosphatidyl inositol phospholipase D activity in human serum
Ann. Clin. Biochem.
32
74-78
1995
Homo sapiens
Rhode, H.; Schulze, M.; Cumme, G.A.; Gohlert, A.; Blume, E.; Bublitz, R.; Schilling, K.; Horn, A.
Glycosylphosphatidylinositol-specific phospholipase D of human serum--activity modulation by naturally occurring amphiphiles
Biol. Chem.
381
471-485
2000
Homo sapiens
Rhode, H.; Lopatta, E.; Schulze, M.; Pascual, C.; Schulze, H.P.; Schubert, K.; Schubert, H.; Reinhart, K.; Horn, A.
Glycosylphosphatidylinositol-specific phospholipase D in blood serum: is the liver the only source of the enzyme?
Clin. Chim. Acta
281
127-145
1999
Homo sapiens, Rattus norvegicus
Schofield, J.N.; Stephens, J.W.; Hurel, S.J.; Bell, K.M.; deSouza, J.B.; Rademacher, T.W.
Insulin reduces serum glycosylphosphatidylinositol phospholipase D levels in human type I diabetic patients and streptozotocin diabetic rats
Mol. Genet. Metab.
75
154-161
2002
Homo sapiens, Rattus norvegicus (Q8R2H5)
Slomiany, A.; Nishikawa, H.; Slomiany, B.L.
Screening and modulation of extracellular signals by mucous barrier. Serum glycosylphosphatidylinositol phospholipase D (GPI-PLD) releases protective mucous barrier from oral mucosa
J. Physiol. Pharmacol.
53
21-38
2002
Rattus norvegicus
Stadelmann, B.; Butikofer, P.; Konig, A.; Brodbeck, U.
The C-terminus of glycosylphosphatidylinositol-specific phospholipase D is essential for biological activity
Biochim. Biophys. Acta
1355
107-113
1997
Bos taurus (P80109)
Tsujioka, H.; Takami, N.; Misumi, Y.; Ikehara, Y.
Intracellular cleavage of glycosylphosphatidylinositol by phospholipase D induces activation of protein kinase Calpha
Biochem. J.
342
449-455
1999
Homo sapiens
Tsujioka, H.; Misumi, Y.; Takami, N.; Ikehara, Y.; Tujioka, H.
Posttranslational modification of glycosylphosphatidylinositol (GPI)-specific phospholipase D and its activity in cleavage of GPI anchors
Biochem. Biophys. Res. Commun.
251
737-743
1998
Homo sapiens
Wilhelm, O.G.; Wilhelm, S.; Escott, G.M.; Lutz, V.; Magdolen, V.; Schmitt, M.; Rifkin, D.B.; Wilson, E.L.; Graeff, H.; Brunner, G.
Cellular glycosylphosphatidylinositol-specific phospholipase D regulates urokinase receptor shedding and cell surface expression
J. Cell. Physiol.
180
225-235
1999
Homo sapiens
LeBoeuf, R.C.; Caldwell, M.; Guo, Y.; Metz, C.; Davitz, M.A.; Olson, L.K.; Deeg, M.A.
Mouse glycosylphosphatidylinositol-specific phospholipase D (Gpld1) characterization
Mamm. Genome
9
710-714
1998
Mus musculus (O70362), Mus musculus
Raikwar, N.S.; Cho, W.K.; Bowen, R.F.; Deeg, M.A.
Glycosylphosphatidylinositol-specific phospholipase D influences triglyceride-rich lipoprotein metabolism
Am. J. Physiol.
290
E463-470
2006
Mus musculus
Yamamoto, Y.; Hirakawa, E.; Mori, S.; Hamada, Y.; Kawaguchi, N.; Matsuura, N.
Cleavage of carcinoembryonic antigen induces metastatic potential in colorectal carcinoma
Biochem. Biophys. Res. Commun.
333
223-229
2005
Homo sapiens
Mann, K.J.; Hepworth, M.R.; Raikwar, N.S.; Deeg, M.A.; Sevlever, D.
Effect of glycosylphosphatidylinositol (GPI)-phospholipase D overexpression on GPI metabolism
Biochem. J.
378
641-648
2004
Mus musculus
Raikwar, N.S.; Bowen, R.F.; Deeg, M.A.
Mutating His29, His125, His133 or His158 abolishes glycosylphosphatidylinositol-specific phospholipase D catalytic activity
Biochem. J.
391
285-289
2005
Mus musculus
Flores-Borja, F.; Kieszkievicz, J.; Church, V.; Francis-West, P.H.; Schofield, J.; Rademacher, T.W.; Lund, T.
Genetic regulation of mouse glycosylphosphatidylinositol-phospholipase D
Biochimie
86
275-282
2004
Mus musculus (Q8R432), Mus musculus
Gregory, P.; Kraemer, E.; Zurcher, G.; Gentinetta, R.; Rohrbach, V.; Brodbeck, U.; Andres, A.C.; Ziemiecki, A.; Butikofer, P.
GPI-specific phospholipase D (GPI-PLD) is expressed during mouse development and is localized to the extracellular matrix of the developing mouse skeleton
Bone
37
139-147
2005
Mus musculus
Naghibalhossaini, F.; Ebadi, P.
Evidence for CEA release from human colon cancer cells by an endogenous GPI-PLD enzyme
Cancer Lett.
234
158-167
2006
Homo sapiens
Jian-Hua, T.; Xiao-Jie, Z.; Yi-Dan, W.; Wen-Kai, L.; Wang-Jiao, H.; Cheng-Hong, W.; Gui-Yuan, L.
Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia
Clin. Chim. Acta
359
115-124
2005
Homo sapiens
Larson, D.M.; Kennedy, M.A.; Bowen, R.F.; Verchere, C.B.; Deeg, M.A.
Glycosylphosphatidylinositol-specific phospholipase D immunoreactivity is present in islet amyloid in type 2 diabetes
J. Pathol.
203
961-967
2004
Homo sapiens
Kurtz, T.A.; Fineberg, N.S.; Considine, R.V.; Deeg, M.A.
Insulin resistance is associated with increased serum levels of glycosylphosphatidylinositol-specific phospholipase D
Metabolism
53
138-139
2004
Homo sapiens
Bonilla, J.B.; Cid, M.B.; Contreras, F.X.; Goni, F.M.; Martin-Lomas, M.
Phospholipase cleavage of D- and L-chiro-glycosylphosphoinositides asymmetrically incorporated into liposomal membranes
Chem. Eur. J.
12
1513-1528
2006
Bos taurus
Chalasani, N.; Vuppalanchi, R.; Raikwar, N.S.; Deeg, M.A.
Glycosylphosphatidylinositol-specific phospholipase D in non-alcoholic fatty liver disease: a preliminary study
J. Clin. Endocrinol. Metab.
91
2279-2285
2006
Homo sapiens
Yoshida, M.; Sakuragi, N.; Kondo, K.; Tanesaka, E.
Cleavage with phospholipase of the lipid anchor in the cell adhesion molecule, csA, from Dictyostelium discoideum
Comp. Biochem. Physiol. B
143B
138-144
2006
Bos taurus (P80109)
-
Watanabe, K.; Bianco, C.; Strizzi, L.; Hamada, S.; Mancino, M.; Bailly, V.; Mo, W.; Wen, D.; Miatkowski, K.; Gonzales, M.; Sanicola, M.; Seno, M.; Salomon, D.S.
Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration
J. Biol. Chem.
282
31643-31655
2007
Homo sapiens
Elortza, F.; Mohammed, S.; Bunkenborg, J.; Foster, L.J.; Nuehse, T.S.; Brodbeck, U.; Peck, S.C.; Jensen, O.N.
Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment
J. Proteome Res.
5
935-943
2006
Bos taurus
Song, K.; Sun, X.; Wang, J.; Zhou, S.; Zeng, H.; Chen, F.
Role of glycosylphosphatidylinositol-specific phospholipase D in the homing of umbilical cord blood, mobilized peripheral blood and bone marrow-derived hematopoietic stem/progenitor cells
Leuk. Res.
31
1701-1707
2007
Homo sapiens (P80108)
Song, K.; Sun, X.; Wang, J.; Chen, F.
How Glycosylphosphatidylinositol-phospholipase D acts in homing of hematopoietic stem/progenitor cells?
Med. Hypotheses
69
660-665
2007
Homo sapiens
Deeg, M.A.; Raikwar, N.S.; Johnson, C.; Williams, C.D.
Statin therapy reduces serum levels of glycosylphosphatidylinositol-specific phospholipase D
Transl. Res.
150
153-157
2007
Homo sapiens
Jian-Hua, T.; Wang-Jiao, H.; He, H.; Chao-Chao, T.; Qiong, D.; Kai-Jia, W.; Xian-Yu, Y.; Xu-Jin, Z.
Important roles of glycosylphosphatidylinositol (GPI)-specific phospholipase D and some GPI-anchored proteins in the pathogenesis of hepatocellular carcinoma
Clin. Biochem.
42
400-407
2009
Homo sapiens
Gray, D.L.; OBrien, K.D.; DAlessio, D.A.; Brehm, B.J.; Deeg, M.A.
Plasma glycosylphosphatidylinositol-specific phospholipase D predicts the change in insulin sensitivity in response to a low-fat but not a low-carbohydrate diet in obese women
Metab. Clin. Exp.
57
473-478
2008
Homo sapiens
Raikwar, N.S.; Bowen-Deeg, R.F.; Du, X.S.; Low, M.G.; Deeg, M.A.
Glycosylphosphatidylinositol-specific phospholipase D improves glucose tolerance
Metab. Clin. Exp.
59
1413-1420
2010
Mus musculus, Mus musculus C57BL/6
Lindqvist, M.; Wallinder, J.; Bergstroem, J.; Henriksson, A.E.
Plasma glycosylphosphatidylinositol phospholipase D (GPI-PLD) and abdominal aortic aneurysm
Int. J. Clin. Exp. Med.
5
306-309
2012
Homo sapiens
Masuda, S.; Fujishima, Y.; Maeda, N.; Tsugawa-Shimizu, Y.; Nakamura, Y.; Tanaka, Y.; Obata, Y.; Fukuda, S.; Nagao, H.; Kita, S.; Nishizawa, H.; Shimomura, I.
Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity
Am. J. Physiol. Endocrinol. Metab.
316
E239-E250
2019
Homo sapiens (P80108), Homo sapiens, Mus musculus (Q7TNZ4), Rattus norvegicus (Q8R2H5)
Ritorto, M.S.; Rhode, H.; Vogel, A.; Borlak, J.
Regulation of glycosylphosphatidylinositol-anchored proteins and GPI-phospholipase D in a c-Myc transgenic mouse model of hepatocellular carcinoma and human HCC
Biol. Chem.
397
1147-1162
2016
Mus musculus (O70362), Mus musculus, Homo sapiens (P80108), Homo sapiens
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