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Information on EC 3.1.4.46 - glycerophosphodiester phosphodiesterase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.4 Phosphoric-diester hydrolases
                3.1.4.46 glycerophosphodiester phosphodiesterase
IUBMB Comments
Broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol and bis(glycerophospho)-glycerol are hydrolysed.
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This record set is specific for:
UNIPROT: P54527
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
glycerophosphodiester phosphodiesterase, lipoprotein d, glpq2, igd-binding protein, glpq1, outer membrane protein d, gpd protein, pfgdpd, gpcpd1, ttgdpd, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glycerophosphodiester phosphodiesterase
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gene hpd protein
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GlpQ
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glycerophosphodiester phosphodiesterase
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glycerophosphoryl diester phosphodiesterase
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-
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GPX-PDE
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-
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IGD-binding protein
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-
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IgD-binding protein D
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immunoglobulin D-binding protein
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phosphodiesterase, glycerophosphodiester
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phosphohydrolase GpdQ
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of carboxylic diester
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PATHWAY SOURCE
PATHWAYS
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-, -, -
SYSTEMATIC NAME
IUBMB Comments
glycerophosphodiester glycerophosphohydrolase
Broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol and bis(glycerophospho)-glycerol are hydrolysed.
CAS REGISTRY NUMBER
COMMENTARY hide
86280-59-3
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
phylogenetic analysis, overview
malfunction
deletion of the yqiHIK operon impairs the growth of Bacillus subtilis at high salinity
physiological function
the enzyme might have a role in osmoprotection
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
YQIK_BACSU
Bacillus subtilis (strain 168)
243
0
27119
Swiss-Prot
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
YqiK is regulated by the same operon yqiHIK as other hydrolytic enzymes
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
high-salinity growth conditions induce the up-regulation of the transcription of the operon yqiHIK encoding the enzyme
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Corda, D.; Mosca, M.; Ohshima, N.; Grauso, L.; Yanaka, N.; Mariggio, S.
The emerging physiological roles of the glycerophosphodiesterase family
FEBS J.
281
998-1016
2014
Agrobacterium tumefaciens, Arabidopsis thaliana, Bacillus pumilus, Bacillus pumilus DSM 27, Bacillus subtilis (P54527), Borrelia hermsii (Q45201), Caldanaerobacter subterraneus subsp. tengcongensis, Escherichia coli (P09394), Escherichia coli (P10908), Haemophilus influenzae (Q06282), Haemophilus influenzae DSM 11121 (Q06282), Homo sapiens (Q8WTR4), Homo sapiens (Q9NPB8), Klebsiella aerogenes, Lupinus albus, Mus musculus, Musca domestica, Mycoplasma hyorhinis (E0TL71), Mycoplasma pneumoniae (P75367), Pasteurella multocida (Q79LP3), Plasmodium falciparum, Rattus norvegicus, Saccharomyces cerevisiae, Saccharomyces cerevisiae (Q02979), Staphylococcus aureus (Q99387), Streptomyces coelicolor, Thermotoga maritima, Treponema pallidum (O30405)
Manually annotated by BRENDA team