Disease on EC 3.1.31.1 - micrococcal nuclease
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Alzheimer Disease
Aluminum, altered transcription, and the pathogenesis of Alzheimer's disease.
Brain Neoplasms
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
Brain Neoplasms
The mechanism of polyamine analog-induced enhancement of cisplatin cytotoxicity in the U-251 MG human malignant glioma cell line.
Breast Neoplasms
Circadian disruption-induced microRNAome deregulation in rat mammary gland tissues.
Breast Neoplasms
Disruption of SND1-MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo.
Breast Neoplasms
MicroRNA-127 is downregulated by Tudor-SN protein and contributes to metastasis and proliferation in breast cancer cell line MDA-MB-231.
Breast Neoplasms
Nucleosomes positioning around transcriptional start site of tumor suppressor (Rbl2/p130) gene in breast cancer.
Breast Neoplasms
SND1 expression in breast cancer tumors is associated with poor prognosis.
Carcinogenesis
Profiling of promoter occupancy by the SND1 transcriptional coactivator identifies downstream glycerolipid metabolic genes involved in TNF? response in human hepatoma cells.
Carcinogenesis
Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (review).
Carcinogenesis
Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGF? signaling.
Carcinoma
Correction: Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11.
Carcinoma
Digestion of RNA of chromatin and nuclear ribonucleoprotein by staphylococcal nuclease.
Carcinoma
Staphylococcal nuclease digestion of relatively stable RNA in the chromatin and nuclear ribonucleoprotein fractions of human carcinoma cells.
Carcinoma
Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11.
Carcinoma
[Two types of attachment points of DNA to the nuclear skeleton in Ehrlich ascites carcinoma cells]
Carcinoma, Hepatocellular
A correlation between nucleosome spacer region susceptibility to DNase I and histone acetylation.
Carcinoma, Hepatocellular
Correlation between gene expression and chromatin conformation of c-fos and N-ras in human liver and hepatoma.
Carcinoma, Hepatocellular
Effects of deoxyribonuclease I and micrococcal nuclease on the release of dexamethasone-receptor complex from nuclei of sensitive and insensitive hepatoma cell lines.
Carcinoma, Hepatocellular
Fractionation of unfixed chromatin by buoyant-density centrifugation in gradients containing 3-iodo-1,2-propanediol and metrizamide.
Carcinoma, Hepatocellular
Localization of phosphoproteins and of protein kinases in chromatin from hepatoma tissue-cultured cells.
Carcinoma, Hepatocellular
Nuclear glycoproteins of hamster liver and Kirkman-Robbins hepatoma recognized by concanavalin A.
Carcinoma, Hepatocellular
Periodicity and fragment size of DNA from mouse TLT hepatoma chromatin and chromatin fractions using endogenous and exogenous nucleases.
Carcinoma, Hepatocellular
Posttranscriptional Inhibition of Protein Tyrosine Phosphatase Nonreceptor Type 23 by Staphylococcal Nuclease and Tudor Domain Containing 1: Implications for Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (review).
Carcinoma, Hepatocellular
Satellite DNA sequence content of polylysine-titratable and nuclease-resistant fractions of mouse liver hepatoma chromatin.
Carcinoma, Hepatocellular
Staphylococcal nuclease and tudor domain containing 1 (SND1) promotes hepatocarcinogenesis by inhibiting monoglyceride lipase (MGLL).
Carcinoma, Hepatocellular
Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGF? signaling.
Carcinoma, Hepatocellular
The multifunction protein, Staphylococcal Nuclease Domain Containing-1 (SND1), promotes tumor angiogenesis in human hepatocellular carcinoma through a novel pathway which involves NF-kappaB and miR-221.
Carcinoma, Hepatocellular
The small chromatin fragments released by micrococcal nuclease from hepatoma tissue cultured cell nuclei are strongly enriched in coding DNA sequences and are related to an actively transcribed single-stranded DNA fraction.
Carcinoma, Hepatocellular
[Proteins and the functional properties of the chromatin fractions from the nuclei of the normal liver and of experimental hepatomas]
Carcinoma, Lewis Lung
Calcium-dependent ADP-ribosylation of high-mobility-group I (HMGI) proteins.
Carcinoma, Non-Small-Cell Lung
Correction: Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11.
Carcinoma, Non-Small-Cell Lung
Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11.
Classical Swine Fever
Inhibition of replication of classical swine fever virus in a stable cell line by the viral capsid and Staphylococcus aureus nuclease fusion protein.
Colitis
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps.
Colitis, Ulcerative
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps.
Colonic Neoplasms
MicroRNA, SND1, and alterations in translational regulation in colon carcinogenesis.
Colonic Neoplasms
SND1, a component of RNA-induced silencing complex, is up-regulated in human colon cancers and implicated in early stage colon carcinogenesis.
Colonic Neoplasms
Two human colon tumor cell lines with similar nuclease sensitivities have different ethidium bromide binding characteristics.
Dehydration
Effect of compensatory organic osmolytes on resistance to freeze-drying of L929 cells and of their isolated chromatin.
Dengue
Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.
Dengue
Development of cell lines stably expressing staphylococcal nuclease fused to dengue 2 virus capsid protein for CTVI.
Dengue
Therapeutic effects of dengue 2 virus capsid protein and staphylococcal nuclease fusion protein on dengue-infected cell cultures.
Dermatitis, Contact
Cross-reactive trinitrophenylated peptides as antigens for class II major histocompatibility complex-restricted T cells and inducers of contact sensitivity in mice. Limited T cell receptor repertoire.
Diabetes Mellitus
Oral delivery of staphylococcal nuclease by Lactococcus lactis prevents type 1 diabetes mellitus in NOD mice.
Diabetes Mellitus, Type 1
Oral delivery of staphylococcal nuclease by Lactococcus lactis prevents type 1 diabetes mellitus in NOD mice.
Encephalitis, Japanese
Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.
Foodborne Diseases
[Dynamics of the production of staphylococcal enterotoxin and thermonuclease in foods responsible for outbreaks of food poisoning]
Gastroenteritis
Coronavirus genomic and subgenomic minus-strand RNAs copartition in membrane-protected replication complexes.
Gastroenteritis, Transmissible, of Swine
Coronavirus genomic and subgenomic minus-strand RNAs copartition in membrane-protected replication complexes.
Glioma
Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (review).
Glioma
Tudor-staphylococcal nuclease regulates the expression and biological function of alkylglycerone phosphate synthase via nuclear factor-?B and microRNA-127 in human glioma U87MG cells.
Graves Disease
Increased micrococcal nuclease sensitivity and/or solubility in nuclei from Graves' disease thyroid tissue.
Hepatitis B
Characterization of nucleosome positioning in hepadnaviral covalently closed circular DNA minichromosomes.
Herpes Simplex
Characterization of herpes simplex virus type 1 DNA during latent infection in mice.
Herpes Simplex
During latency, herpes simplex virus type 1 DNA is associated with nucleosomes in a chromatin structure.
Herpes Simplex
During lytic infections, herpes simplex virus type 1 DNA is in complexes with the properties of unstable nucleosomes.
Herpes Simplex
Herpes Simplex Virus Type 1 DNA is in unstable nucleosomes throughout the lytic infection cycle independently of DNA replication.
Herpes Simplex
Intracellular organization of herpes simplex virus type 1 DNA assayed by staphylococcal nuclease sensitivity.
Herpes Simplex
Random cleavage of intranuclear herpes simplex virus DNA by micrococcal nuclease.
Herpes Simplex
The structure of herpes simplex virus type 1 DNA as probed by micrococcal nuclease digestion.
Hyperglycemia
Polyploidy and chromatin remodeling in hepatocytes from insulin-dependent diabetic and normoglycemic aged mice.
Hypersensitivity
A close association between sites of DNase I hypersensitivity and sites of enhanced cleavage by micrococcal nuclease in the 5'-flanking region of the actively transcribed ovalbumin gene.
Hypersensitivity
A family of cAMP-response-element-related DNA sequences with meiotic recombination hotspot activity in Schizosaccharomyces pombe.
Hypersensitivity
Active transcription of the human FASL/CD95L/TNFSF6 promoter region in T lymphocytes involves chromatin remodeling: role of DNA methylation and protein acetylation suggest distinct mechanisms of transcriptional repression.
Hypersensitivity
Attachment to the nuclear matrix mediates specific alterations in chromatin structure.
Hypersensitivity
Chromatin structure at the 44D larval cuticle gene locus in Drosophila: the effect of a transposable element insertion.
Hypersensitivity
Competitive inactivation of a double-strand DNA break site involves parallel suppression of meiosis-induced changes in chromatin configuration.
Hypersensitivity
Differential acetylation of histone H3 at the regulatory region of OsDREB1b promoter facilitates chromatin remodelling and transcription activation during cold stress.
Hypersensitivity
Genome-wide MNase hypersensitivity assay unveils distinct classes of open chromatin associated with H3K27me3 and DNA methylation in Arabidopsis thaliana.
Hypersensitivity
Histone acetylation and chromatin remodeling are required for UV-B-dependent transcriptional activation of regulated genes in maize.
Hypersensitivity
Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1-binding sites.
Hypersensitivity
Major changes in the 5' and 3' chromatin structure of sea urchin histone genes accompany their activation and inactivation in development.
Hypersensitivity
NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.
Hypersensitivity
Nucleosomes are translationally positioned on the active allele and rotationally positioned on the inactive allele of the HPRT promoter.
Hypersensitivity
Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.
Hypersensitivity
Structure of chromatin at deoxyribonucleic acid replication forks: nuclease hypersensitivity results from both prenucleosomal deoxyribonucleic acid and an immature chromatin structure.
Hypersensitivity
The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors.
Hypersensitivity
The Higher Structure of Chromatin in the LCR of the beta-Globin Locus Changes during Development.
Hypersensitivity
The meiotic recombination hot spot created by the single-base substitution ade6-M26 results in remodeling of chromatin structure in fission yeast.
Hypersensitivity
Tissue-specific chromatin structure of the phenobarbital-responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital.
Hypersensitivity
Transcription elongation factors repress transcription initiation from cryptic sites.
Hypersensitivity
[Structuro-functional organization of the SV40 virus chromosome. IV. Specific organization of regulatory sequences of the SV40 genome in the mini-chromosome]
Infections
A novel method of selective removal of human DNA improves PCR sensitivity for detection of Salmonella Typhi in blood samples.
Infections
Adenoviral protein VII packages intracellular viral DNA throughout the early phase of infection.
Infections
Centromere architecture breakdown induced by the viral E3 ubiquitin ligase ICP0 protein of herpes simplex virus type 1.
Infections
Detection of staphylococcal nuclease elaborated during lethal infections in mice.
Infections
Development of cell lines stably expressing staphylococcal nuclease fused to dengue 2 virus capsid protein for CTVI.
Infections
During lytic infection herpes simplex virus type 1 is associated with histones bearing modifications that correlate with active transcription.
Infections
Genome Wide Nucleosome Mapping for HSV-1 Shows Nucleosomes Are Deposited at Preferred Positions during Lytic Infection.
Infections
In vitro inhibition of Japanese encephalitis virus replication by capsid-targeted virus inactivation.
Infections
Inhibition of replication of classical swine fever virus in a stable cell line by the viral capsid and Staphylococcus aureus nuclease fusion protein.
Infections
Intracellular organization of herpes simplex virus type 1 DNA assayed by staphylococcal nuclease sensitivity.
Infections
Mycoplasma agalactiae MAG_5040 is a Mg(2+)-Dependent, Sugar-Nonspecific SNase Recognised by the Host Humoral Response during Natural Infection.
Infections
Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps.
Infections
Nuclease Tudor-SN Is Involved in Tick dsRNA-Mediated RNA Interference and Feeding but Not in Defense against Flaviviral or Anaplasma phagocytophilum Rickettsial Infection.
Infections
SND1 promotes Th1/17 immunity against chlamydial lung infection through enhancing dendritic cell function.
Infections
Therapeutic effects of dengue 2 virus capsid protein and staphylococcal nuclease fusion protein on dengue-infected cell cultures.
Infections
Therapeutic effects of duck Tembusu virus capsid protein fused with staphylococcal nuclease protein to target Tembusu infection in vitro.
Infections
Transient silencing of Plasmodium falciparum Tudor Staphylococcal Nuclease suggests an essential role for the protein.
Influenza, Human
Influenza A virus RNA-dependent RNA polymerase cleaves influenza mRNA in vitro.
Influenza, Human
Influenza A virus RNA-dependent RNA polymerase: analysis of RNA synthesis in vitro.
Insulin Resistance
Global Tudor-SN transgenic mice are protected from obesity-induced hepatic steatosis and insulin resistance.
Keloid
PAX5 activates telomerase activity and proliferation in keloid fibroblasts by transcriptional regulation of SND1, thus promoting keloid growth in burn-injured skin.
Leukemia
Altered nucleosome spacing in newly replicated chromatin from Friend leukemia cells.
Leukemia
Appearance of a new nucleosomal protein during differentiation of human leukemia (HL-60) cells.
Leukemia
Therapeutic effect of a Gag-nuclease fusion protein against retroviral infection in vivo.
Leukemia, Erythroblastic, Acute
Alterations in globin gene chromatin conformation during murine erythroleukemia cell differentiation.
Leukemia, Erythroblastic, Acute
Localization of DNA methyltransferase in the chromatin of Friend erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Nucleosome disruption precedes transcription and is largely limited to the transcribed domain of globin genes in murine erythroleukemia cells.
Leukemia, Erythroblastic, Acute
Organizational changes in chromatin at different malignant stages of Friend erythroleukemia.
Leukemia, Erythroblastic, Acute
Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.
Liver Neoplasms, Experimental
Drug action and chromatin structure. I. Adriamycin binding to core particle of nucleosomes and subsequent enhanced DNA fragmentation induced by micrococcal nuclease.
Liver Neoplasms, Experimental
Effects of divalent metal cations on composition and neoplasia-specific antigenicity of chromatins.
Marek Disease
Purification of DNA from the cell-associated herpesvirus Marek's disease virus for 454 pyrosequencing using micrococcal nuclease digestion and polyethylene glycol precipitation.
Mastitis
Antibodies against Staphylococcus aureus nuclease in bulk milk as an indicator of mastitis in dairy herds.
Mastitis
Genetic relatedness, antibiogram and virulence factors of Staphylococcus aureus isolated from bovine mastitis and related human contacts.
Mastitis
Staphylococcal enterotoxin and thermonuclease production during induced bovine mastitis and the clinical reaction of enterotoxin in udders.
Measles
Measles virus nucleocapsid protein can function in Sendai virus defective interfering particle genome synthesis in vitro.
Multiple Myeloma
Preferential in vivo DNA repair of melphalan-induced damage in human genes is greatly affected by the local chromatin structure.
Nasopharyngeal Carcinoma
[The improvewment of DNA library construction in non-crosslinked chromatin immunoprecipitation coupled with next-generation sequencing].
Neoplasm Metastasis
MicroRNA-127 is downregulated by Tudor-SN protein and contributes to metastasis and proliferation in breast cancer cell line MDA-MB-231.
Neoplasm Metastasis
MiR-361-5p inhibits colorectal and gastric cancer growth and metastasis by targeting staphylococcal nuclease domain containing-1.
Neoplasm Metastasis
SND1 acts upstream of SLUG to regulate the epithelial-mesenchymal transition (EMT) in SKOV3 cells.
Neoplasm Metastasis
SND1 expression in breast cancer tumors is associated with poor prognosis.
Neoplasms
A pan-cancer analysis of the oncogenic role of staphylococcal nuclease domain-containing protein 1 (SND1) in human tumors.
Neoplasms
Histone hyperacetylation does not alter the positioning or stability of phased nucleosomes on the mouse mammary tumor virus long terminal repeat.
Neoplasms
MicroRNA-127 is downregulated by Tudor-SN protein and contributes to metastasis and proliferation in breast cancer cell line MDA-MB-231.
Neoplasms
Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress.
Neoplasms
PAX5 activates telomerase activity and proliferation in keloid fibroblasts by transcriptional regulation of SND1, thus promoting keloid growth in burn-injured skin.
Neoplasms
Persistence of the ten-nucleotide repeat in chromatin unfolded in urea, as revealed by digestion with deoxyribonuclease i.
Neoplasms
Posttranscriptional Inhibition of Protein Tyrosine Phosphatase Nonreceptor Type 23 by Staphylococcal Nuclease and Tudor Domain Containing 1: Implications for Hepatocellular Carcinoma.
Neoplasms
SND1 acts as a novel gene transcription activator recognizing the conserved Motif domains of Smad promoters, inducing TGF?1 response and breast cancer metastasis.
Neoplasms
SND1 acts upstream of SLUG to regulate the epithelial-mesenchymal transition (EMT) in SKOV3 cells.
Neoplasms
SND1 facilitates the invasion and migration of cervical cancer cells by Smurf1-mediated degradation of FOXA2.
Neoplasms
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX?2/PGE2 expression via activation of NF??B.
Neoplasms
Staphylococcal nuclease and tudor domain containing 1 (SND1) promotes hepatocarcinogenesis by inhibiting monoglyceride lipase (MGLL).
Neoplasms
The extraction by micrococcal nuclease of glucocorticoid receptors and mouse mammary tumor virus DNA sequences is dissociated.
Neoplasms
The multifunction protein, Staphylococcal Nuclease Domain Containing-1 (SND1), promotes tumor angiogenesis in human hepatocellular carcinoma through a novel pathway which involves NF-kappaB and miR-221.
Neoplasms
Tudor-staphylococcal nuclease regulates the expression and biological function of alkylglycerone phosphate synthase via nuclear factor-?B and microRNA-127 in human glioma U87MG cells.
Neuroblastoma
Structural features of the amplified N-myc oncogene detected by micrococcal nuclease digestion of neuroblastoma cell nuclei.
Newcastle Disease
Cell-free coupling of Newcastle disease virus RNA transcription, translation and Co-translational processing.
Obesity
Global Tudor-SN transgenic mice are protected from obesity-induced hepatic steatosis and insulin resistance.
Ovarian Neoplasms
Cloning and expression of the H chain V region of antibody OVB3 that reacts with human ovarian cancer.
Photosensitivity Disorders
Effect of Photodynamic Therapy on the Virulence Factors of Staphylococcus aureus.
Prostatic Neoplasms
Staphylococcal Nuclease Domain-Containing Protein 1 as a Potential Tissue Marker for Prostate Cancer.
Respiratory Tract Infections
Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps.
Retinoblastoma
Structural features of the amplified N-myc oncogene detected by micrococcal nuclease digestion of neuroblastoma cell nuclei.
Sarcoma
Replicative DNA synthesis and unscheduled DNA synthesis in permeable sarcoma cells studied by nuclease digestion.
Sarcoma, Yoshida
Cellular factors for stimulation of nucleosomal template activity for in vitro DNA synthesis.
Shock, Septic
Characterisation of mecA gene negative Staphylococcus aureus isolated from bovine mastitis milk from Northern Germany.
Shock, Septic
The role of virulence factors in the outcome of staphylococcal peritonitis in CAPD patients.
Starvation
In vivo topography of Rap1p-DNA complex at Saccharomyces cerevisiae TEF2 UAS(RPG) during transcriptional regulation.
Starvation
Rice nucleosome patterns undergo remodeling coincident with stress-induced gene expression.
Stomach Neoplasms
MiR-361-5p inhibits colorectal and gastric cancer growth and metastasis by targeting staphylococcal nuclease domain containing-1.
Typhoid Fever
A novel method of selective removal of human DNA improves PCR sensitivity for detection of Salmonella Typhi in blood samples.
Vaccinia
Discriminatory inhibition of protein synthesis in cell-free systems by vaccinia virus transcripts.
Vaccinia
Identification of factors specific for transcription of the late class of vaccinia virus genes.
Vesicular Stomatitis
Two distinct populations of vesicular stomatitis virus ribonucleoprotein cores with differential sensitivities to micrococcal nuclease.
Virus Diseases
Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut.
Xeroderma Pigmentosum
Similar distributions of repaired sites in chromatin of normal and xeroderma pigmentosum variant cells damaged by ultraviolet light.
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