Disease on EC 3.1.30.1 - Aspergillus nuclease S1
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Adenocarcinoma
Isolation and characterization of a partial cDNA for a human sialyltransferase.
Adenocarcinoma
[Detection of Ki-ras oncogene mutations in normal mucosa, adenoma and adenocarcinoma of the colon]
Adenoma
[Detection of Ki-ras oncogene mutations in normal mucosa, adenoma and adenocarcinoma of the colon]
alpha-Thalassemia
S1 nuclease analysis of alpha-globin gene expression in preleukemic patients with acquired hemoglobin H disease after transfer to mouse erythroleukemia cells.
Alzheimer Disease
Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients.
Alzheimer Disease
Cerebral cortical amyloid protein precursor mRNA expression is similar in Alzheimer's disease and other neurodegenerative diseases.
Alzheimer Disease
Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis.
Brain Neoplasms
Multiple transcripts of the neurofibromatosis type 1 gene in human brain and in brain tumours.
Brain Neoplasms
S1-nuclease enhancement of the ethidium bromide binding assay of drug-induced DNA interstrand crosslinking in human brain tumor cells.
Breast Neoplasms
A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells.
Breast Neoplasms
C-erbB-2-oncogene expression in breast carcinoma: analysis by S1 nuclease protection assay and immunohistochemistry in relation to clinical parameters.
Breast Neoplasms
Expression of the human androgen receptor gene utilizes a common promoter in diverse human tissues and cell lines.
Breast Neoplasms
Gonadotropin-releasing hormone gene expression in MDA-MB-231 and ZR-75-1 breast carcinoma cell lines.
Breast Neoplasms
Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines.
Breast Neoplasms
PCR-Free Quantification of Multiple Splice Variants in a Cancer Gene by Surface-Enhanced Raman Spectroscopy.
Burkitt Lymphoma
Differential expression of the normal and of the translocated human c-myc oncogenes in B cells.
Burkitt Lymphoma
The intron enhancer of the immunoglobulin kappa gene activates c-myc but does not induce the Burkitt-specific promoter shift.
Carcinoid Tumor
The human tryptophan hydroxylase gene. An unusual splicing complexity in the 5'-untranslated region.
Carcinoma
C-myc mRNA expression in epithelial ovarian carcinomas in relation to estrogen receptor status, metastatic spread, survival time, FIGO stage, and histologic grade and type.
Carcinoma
Fine structure of the cottontail rabbit papillomavirus mRNAs expressed in the transplantable VX2 carcinoma.
Carcinoma
Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.
Carcinoma, Ehrlich Tumor
Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene.
Carcinoma, Embryonal
Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex.
Carcinoma, Hepatocellular
Cell-specific expression of mouse albumin promoter. Evidence for cell-specific DNA elements within the proximal promoter region and cis-acting DNA elements upstream of -160.
Carcinoma, Hepatocellular
Isolation and characterization of a partial cDNA for a human sialyltransferase.
Carcinoma, Ovarian Epithelial
C-myc mRNA expression in epithelial ovarian carcinomas in relation to estrogen receptor status, metastatic spread, survival time, FIGO stage, and histologic grade and type.
Choriocarcinoma
Expression of the germ cell alkaline phosphatase gene in human choriocarcinoma cells.
Citrullinemia
Structure of an abnormal messenger RNA for argininosuccinate synthetase in citrullinemia.
Coma
Cloning and characterization of the regulatory Bacillus subtilis competence genes comA and comB.
Cystic Fibrosis
Enzymatic and chemical probing of an S1 nuclease-sensitive site upstream from the human CFTR gene.
Dengue
Comparison of dengue viruses and some other flaviviruses by cDNA-RNA hybridization analysis and detection of a close relationship between dengue virus serotype 2 and Edge Hill virus.
Endometrial Neoplasms
Expression of aberrant estrogen receptor mRNA in endometrial cancers in comparison with normal endometria.
Fanconi Anemia
Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells.
Gaucher Disease
Human acid beta-glucosidase: Northern blot and S1 nuclease analysis of mRNA from HeLa cells and normal and Gaucher disease fibroblasts.
Glioblastoma
An S1 nuclease-sensitive region in the first intron of human platelet-derived growth factor A-chain gene contains a negatively acting cell type-specific regulatory element.
Glioma
Messenger RNA populations and their nuclear precursors in cultured human glioma and fetal brain cells.
Gliosarcoma
S1 nuclease from Aspergillus oryzae for the detection of DNA damage and repair in the gamma-irradiated intracerebral rat gliosarcoma 9L.
Hemangioma
The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells.
Hepatitis
[Presence and replication of TTV DNA in peripheral blood mononuclear cells from hepatitis patients with TTV infection]
Hepatitis A
Detection of defective genomes in hepatitis A virus particles present in clinical specimens.
Herpes Simplex
Immediate-early mRNA-2 of herpes simplex viruses types 1 and 2 is unspliced: conserved sequences around the 5' and 3' termini correspond to transcription regulatory signals.
Herpes Simplex
Mutagenesis of a herpes simplex virus origin of DNA replication and its effect on viral interference.
Herpes Simplex
Organization of the herpes simplex virus type 1 transcription unit encoding two early proteins with molecular weights of 140000 and 40000.
Herpes Simplex
Temporal regulation of herpes simplex virus type 1 UL24 mRNA expression via differential polyadenylation.
Herpes Simplex
The promoter for the late gene encoding Vp5 of herpes simplex virus type 1 is recognized by cell extracts derived from uninfected cells.
Hyperlipoproteinemia Type II
Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit.
Hypersensitivity
A cytosine . cytosine base paired parallel DNA double helix with thymine . thymine bulges.
Hypersensitivity
Anatomy of the stimulative sequences flanking the ARS consensus sequence of chromosome VI in Saccharomyces cerevisiae.
Hypersensitivity
cis-acting components in the replication origin from ribosomal DNA of Saccharomyces cerevisiae.
Hypersensitivity
Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation.
Hypersensitivity
Nuclear factor binding to a DNA sequence element that represses MMTV transcription induces a structural transition and leads to the contact of single-stranded binding proteins with DNA.
Hypersensitivity
P1 nuclease defines a subpopulation of active SV40 chromatin--a new nuclease hypersensitivity assay.
Hypersensitivity
Pseudoknot-dependent read-through of retroviral gag termination codons: importance of sequences in the spacer and loop 2.
Hypersensitivity
Sea urchin egg mitochondrial DNA contains a short displacement loop (D-loop) in the replication origin region.
Hypersensitivity
Sequence-dependent S1 nuclease hypersensitivity of a heteronomous DNA duplex.
Hypersensitivity
Stable DNA unwinding, not "breathing," accounts for single-strand-specific nuclease hypersensitivity of specific A+T-rich sequences.
Hypersensitivity
Supercoil induced S1 hypersensitive sites in the rat and human ribosomal RNA genes.
Hypersensitivity
Superhelicity induces hypersensitivity of a human polypyrimidine . polypurine DNA sequence in the human alpha 2-alpha 1 globin intergenic region to S1 nuclease digestion--high resolution mapping of the clustered cleavage sites.
Hypersensitivity
Tertiary base pair interactions in slipped loop-DNA: an NMR and model building study.
Hypersensitivity
The AUUCU repeats responsible for spinocerebellar ataxia type 10 form unusual RNA hairpins.
Hypersensitivity
The cAMP response element in the rat thyrotropin receptor promoter. Regulation by each decanucleotide of a flanking tandem repeat uses different, additive, and novel mechanisms.
Hypersensitivity
The DNA unwinding element in a yeast replication origin functions independently of easily unwound sequences present elsewhere on a plasmid.
Hypersensitivity
The DNA unwinding element: a novel, cis-acting component that facilitates opening of the Escherichia coli replication origin.
Hypersensitivity
The inefficient replication origin from yeast ribosomal DNA is naturally impaired in the ARS consensus sequence and in DNA unwinding.
Hypersensitivity
Unusual DNA sequences located within the promoter region and the first intron of the chicken pro-alpha 1(I) collagen gene.
Hyperthyroidism
Expression of rabbit ventricular alpha-myosin heavy chain messenger RNA sequences in atrial muscle.
Infections
A constitutively expressed vaccinia gene encodes a 42-kDa glycoprotein related to complement control factors that forms part of the extracellular virus envelope.
Infections
A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences.
Infections
Analysis of the major transcripts encoded by the long repeat of human cytomegalovirus strain AD169.
Infections
Changes in the topography of early region transcription during polyoma virus lytic infection.
Infections
Expression of an equine herpesvirus 1 ICP22/ICP27 hybrid protein encoded by defective interfering particles associated with persistent infection.
Infections
Identification and characterization of a murine cytomegalovirus gene with homology to the UL25 open reading frame of human cytomegalovirus.
Infections
Organization of six early transcripts synthesized from a vaccinia virus EcoRI DNA fragment.
Infections
Quantitative real-time PCR for titration of infectious recombinant AAV-2 particles.
Infections
Retroregulation of the bacteriophage lambda int gene: limited secondary degradation of the RNase III-processed transcript.
Infections
Sequence complexity and relative abundance of vaccinia virus mRNA's synthesized in vivo and in vitro.
Infections
Specific site of action for single-strand specific nuclease on the double-stranded circular DNA intermediates of an avian RNA tumor virus.
Infections
Temperature-sensitive vaccinia virus mutants identify a gene with an essential role in viral replication.
Infections
The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle.
Infections
The vaccinia virus A4OR gene product is a nonstructural, type II membrane glycoprotein that is expressed at the cell surface.
Infections
Total sequence, flanking regions, and transcripts of bacteriophage T4 nrdA gene, coding for alpha chain of ribonucleoside diphosphate reductase.
Infections
Trans activation of plasmid-borne promoters by adenovirus and several herpes group viruses.
Infections
Transcription initiation sites of prototype and variant JC virus early and late messenger RNAs.
Infections
Vaccinia virus encodes a thymidylate kinase gene: sequence and transcriptional mapping.
Leukemia
Heteroduplex analysis using flow cytometric microbead assays to detect deletions, insertions, and single-strand lesions.
Leukemia
Identification of a RNA polymerase II initiation site in the long terminal repeat of Moloney murine leukemia viral DNA.
Leukemia
Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines.
Leukemia
Potentiation of DNA adduct formation in HL-60 cells by combinations of benzene metabolites.
Leukemia
Pseudoknot-dependent read-through of retroviral gag termination codons: importance of sequences in the spacer and loop 2.
Leukemia
Slipped DNA structures within the enhancer region of the Moloney murine leukemia virus.
Leukemia, Erythroblastic, Acute
Changes in the levels of three different classes of histone mRNA during murine erythroleukemia cell differentiation.
Leukemia, Erythroblastic, Acute
Expression of a gene for mouse eucaryotic elongation factor Tu during murine erythroleukemic cell differentiation.
Leukemia, Erythroblastic, Acute
Nuclear precursor molecules of the two beta-globin mRNAs in Friend erythroleukemia cells.
Leukemia, Erythroblastic, Acute
S1 nuclease analysis of alpha-globin gene expression in preleukemic patients with acquired hemoglobin H disease after transfer to mouse erythroleukemia cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Interleukin 1 gene expression in adult T cell leukemia.
Leukemia, T-Cell
Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.
Lupus Erythematosus, Systemic
A sensitive solid phase microradioimmunoassay for anti-double stranded DNA antibodies.
Lyme Disease
Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis.
Lymphoma, B-Cell
Constitutive production of lymphokines by cloned murine B-cell lymphomas--CH12 B lymphoma produces interleukin-4.
Malaria
Profiling the malaria genome: a gene survey of three species of malaria parasite with comparison to other apicomplexan species.
Melanoma
Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene.
Melanoma
Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines.
Neoplasm Metastasis
Parathyroid hormone-related protein in an esophageal squamous cell carcinoma with tumor-induced hypercalcemia.
Neoplasms
A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells.
Neoplasms
Characterization of the BCR promoter in Philadelphia chromosome-positive and -negative cell lines.
Neoplasms
Chromosome translocations clustered 5' of the murine c-myc gene qualitatively affect promoter usage: implications for the site of normal c-myc regulation.
Neoplasms
Comparative and quantitative study of L-dopa decarboxylase mRNA in rat neuronal and non-neuronal tissues.
Neoplasms
Differential expression of two classes of lck transcripts upon phorbol ester treatment of human leukemic T cells.
Neoplasms
Frequent detection of the replicative form of TT virus DNA in peripheral blood mononuclear cells and bone marrow cells in cancer patients.
Neoplasms
Functional analysis of the glucocorticoid regulatory elements present in the mouse mammary tumor virus long terminal repeat. A synthetic distal binding site can replace the proximal binding domain.
Neoplasms
Human alpha 3(VI) collagen gene. Characterization of exons coding for the amino-terminal globular domain and alternative splicing in normal and tumor cells.
Neoplasms
Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene.
Neoplasms
Interleukin-7 receptor expression and activation in nonhaematopoietic neoplastic cell lines.
Neoplasms
Map locations of five transcripts homologous to TR-DNA in tobacco and sunflower crown gall tumors.
Neoplasms
Molecular cloning and sequencing of the MTV-1 LTR: evidence for a LTR sequence alteration.
Neoplasms
Multiple transcripts of the neurofibromatosis type 1 gene in human brain and in brain tumours.
Neoplasms
Mutations in the hormone regulatory element of mouse mammary tumor virus differentially affect the response to progestins, androgens, and glucocorticoids.
Neoplasms
Next-Generation Sequencing Using S1 Nuclease for Poor-Quality Formalin-Fixed, Paraffin-Embedded Tumor Specimens.
Neoplasms
Nucleotide sequence and transcript map of the Agrobacterium tumefaciens Ti plasmid-encoded octopine synthase gene.
Neoplasms
Nucleotide sequence of the Agrobacterium tumefaciens octopine Ti plasmid-encoded tmr gene.
Neoplasms
Overexpression of vasopressin (V3) and corticotrophin-releasing hormone receptor genes in corticotroph tumours.
Neoplasms
Parathyroid hormone-related protein in an esophageal squamous cell carcinoma with tumor-induced hypercalcemia.
Neoplasms
Pro-opiomelanocortin mRNA size heterogeneity in ACTH-dependent Cushing's syndrome.
Neoplasms
Proopiomelanocortin gene expression in a pheochromocytoma using upstream transcription initiation sites.
Neoplasms
Qualitative and quantitative changes of human tenascin expression in transformed lung fibroblast and lung tumor tissues: comparison with fibronectin.
Neoplasms
Reduced expression of neurofibromin in the soft tissue tumours obtained from patients with neurofibromatosis type I.
Neoplasms
Regulation of androgen receptor expression in the human heterotransplantable prostate carcinoma PC-82.
Neoplasms
Site-directed mutagenesis of the enhancer region of the 780 gene promoter of T-DNA.
Neoplasms
Specific site of action for single-strand specific nuclease on the double-stranded circular DNA intermediates of an avian RNA tumor virus.
Neoplasms
Transcription of the simian virus 40 genome in DNA-transformed murine teratocarcinoma stem cells.
Neuroblastoma
Complete nucleotide sequence of human vasoactive intestinal peptide/PHM-27 gene and its inducible promoter.
Neuroblastoma
Expression of alternatively spliced src messenger RNAs related to neuronal differentiation in human neuroblastomas.
Neurodegenerative Diseases
Cerebral cortical amyloid protein precursor mRNA expression is similar in Alzheimer's disease and other neurodegenerative diseases.
Neurofibromatoses
Multiple transcripts of the neurofibromatosis type 1 gene in human brain and in brain tumours.
Neurofibromatoses
Reduced expression of neurofibromin in the soft tissue tumours obtained from patients with neurofibromatosis type I.
Neurofibromatosis 1
Multiple transcripts of the neurofibromatosis type 1 gene in human brain and in brain tumours.
Neurofibromatosis 1
Reduced expression of neurofibromin in the soft tissue tumours obtained from patients with neurofibromatosis type I.
Osteogenesis Imperfecta
Nuclease S1 mapping of a homozygous mutation in the carboxyl-propeptide-coding region of the pro alpha 2(I) collagen gene in a patient with osteogenesis imperfecta.
Paratuberculosis
Unexpected detection of DNA by nucleic acid sequence-based amplification technique.
Persistent Infection
Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection.
Pituitary Neoplasms
Isolation and characterization of the human thyrotropin beta-subunit gene. Differences in gene structure and promoter function from murine species.
Plasmacytoma
Differential expression of the normal and of the translocated human c-myc oncogenes in B cells.
Prostatic Neoplasms
Expression of the human androgen receptor gene utilizes a common promoter in diverse human tissues and cell lines.
Pseudohypoparathyroidism
Reduced expression of multiple forms of the alpha subunit of the stimulatory GTP-binding protein in pseudohypoparathyroidism type Ia.
Rabies
Primary structure of leader RNA and nucleoprotein genes of the rabies genome: segmented homology with VSV.
Sarcoma
S1 nuclease mapping of viral RNAs from a temperature-sensitive transformation mutant of murine sarcoma virus.
Sarcoma
Structure of the rat PRPS1 gene encoding phosphoribosylpyrophosphate synthetase subunit I.
Sarcoma, Avian
Avian sarcoma virus gag and env gene structural protein precursors contain a common amino-terminal sequence.
Sarcoma, Avian
The leader sequence of the subgenomic mRNA's of Rous sarcoma virus is approximately 390 nucleotides.
Scleroderma, Systemic
Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1.
Seizures
Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus.
Seizures
Seizure-induced increases in NGF mRNA exhibit different time courses across forebrain regions and are biphasic in hippocampus.
Seizures
Seizures increase basic fibroblast growth factor mRNA in adult rat forebrain neurons and glia.
Starvation
Transcription of all amoC copies is associated with recovery of Nitrosomonas europaea from ammonia starvation.
Thalassemia
Abnormally spliced messenger RNA in erythroid cells from patients with beta+ thalassemia and monkey cells expressing a cloned beta+-thalassemic gene.
Trypanosomiasis, African
Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei.
Tuberculosis
An essential two-component signal transduction system in Mycobacterium tuberculosis.
Tuberculosis
Characterization of a Mycobacterium tuberculosis homologue of the Streptomyces coelicolor whiB gene.
Vaccinia
Characterization of vaccinia virus early promoters and evaluation of their informational content.
Vaccinia
Fine structure analysis and nucleotide sequence of the vaccinia virus thymidine kinase gene.
Vaccinia
Sequence and transcriptional analysis of an orf virus gene encoding ankyrin-like repeat sequences.
Vaccinia
The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle.
Vaccinia
Vaccinia virus ribonucleotide reductase. Correlation between deoxyribonucleotide supply and demand.
Vaccinia
Vaccinia virus-like early transcriptional control sequences flank an early gene in orf virus.
Virus Diseases
Detection of defective genomes in hepatitis A virus particles present in clinical specimens.
Virus Diseases
Nucleotide sequence and transcript organization of a region of the vaccinia virus genome which encodes a constitutively expressed gene required for DNA replication.
Virus Diseases
Sequence-specific interference by small RNAs derived from adenovirus VAI RNA.
Warts
Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissues.
Xeroderma Pigmentosum
Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells.
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