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Information on EC 3.1.3.94 - D-galactose 1-phosphate phosphatase
for references in articles please use BRENDA:EC3.1.3.94
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EC Tree 3 Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.94 D-galactose 1-phosphate phosphatase
IUBMB Comments
The human enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase. The enzyme has very low activity with L-galactose 1-phosphate (cf. EC 3.1.3.93, L-galactose 1-phosphate phosphatase).
The enzyme appears in viruses and cellular organisms
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REACTION 
REACTION DIAGRAM
COMMENTARY 
ORGANISM
UNIPROT
LITERATURE
alpha-D-galactose 1-phosphate + H2O = D-galactose + phosphate
-
-
-
-
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SYSTEMATIC NAME
IUBMB Comments
alpha-D-galactose-1-phosphate phosphohydrolase
The human enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase. The enzyme has very low activity with L-galactose 1-phosphate (cf. EC 3.1.3.93, L-galactose 1-phosphate phosphatase).
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: -
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: the enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: -
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: the enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: -
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: the enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase
Products: -
Products: -
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: -
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: -
Products: -
Products: -
?
alpha-D-galactose 1-phosphate + H2O
D-galactose + phosphate
-
Substrates: -
Products: -
Products: -
?
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Mg2+
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Li+
-
0.1 mM to 10 mM, the lithium inhibition profile is uncompetitive type
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
Highest Expressing Human Cell Lines
Cell Line LinksPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). A0A1A8BH78_NOTKA
188
0
20457
TrEMBL
Secretory Pathway (Reliability: 1)
A0A2D4KVG8_9SAUR
157
0
17062
TrEMBL
Mitochondrion (Reliability: 5)
A0A3Q2CQS5_CYPVA
170
0
18063
TrEMBL
other Location (Reliability: 5)
A0A4W2H595_BOBOX
437
0
48122
TrEMBL
other Location (Reliability: 5)
A0A4W2HDL6_BOBOX
458
0
49243
TrEMBL
other Location (Reliability: 5)
A0A662YZ01_ACIRT
604
0
66288
TrEMBL
other Location (Reliability: 2)
A0A6B0QQ44_9CETA
1007
0
111653
TrEMBL
Secretory Pathway (Reliability: 2)
A0A8C0TBI6_CANLF
519
0
56656
TrEMBL
Mitochondrion (Reliability: 5)
A0A8C3MXB0_GEOPR
79
0
8309
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8C6AI03_MONMO
494
0
53975
TrEMBL
other Location (Reliability: 3)
A0A8J6G5B7_MICOH
243
0
26532
TrEMBL
other Location (Reliability: 2)
A0A8T2P7T8_9TELE
122
0
13034
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8T3E647_9TELE
568
0
61653
TrEMBL
other Location (Reliability: 3)
A0AAD4TV67_OVIAM
484
0
52857
TrEMBL
Secretory Pathway (Reliability: 2)
U6DYF9_NEOVI
88
0
9318
TrEMBL
Secretory Pathway (Reliability: 1)
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PDB
SCOP
CATH
UNIPROT
ORGANISM
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
29000
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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
80
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Parthasarathy, R.; Parthasarathy, L.; Vadnal, R.
Brain inositol monophosphatase identified as a galactose 1-phosphatase
Brain Res.
778
99-106
1997
Bos taurus, Homo sapiens, Rattus norvegicus
brenda
EXTERNAL LINKS (specific for EC-Number 3.1.3.94)
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