Reference on EC 3.1.3.86 - phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Jackson, S.P.; Schoenwaelder, S.M.; Matzaris, M.; Brown, S.; Mitchell, C.A.
Phosphatidylinositol 3,4,5-trisphosphate is a substrate for the 75 kDa inositol polyphosphate 5-phosphatase and a novel 5-phosphatase which forms a complex with the p85/p110 form of phosphoinositide 3-kinase
EMBO J.
14
4490-4500
1995
Homo sapiens
Vandeput, F.; Backers, K.; Villeret, V.; Pesesse, X.; Erneux, C.
The influence of anionic lipids on SHIP2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase activity
Cell. Signal.
18
2193-2199
2006
Homo sapiens
Drayer, A.L.; Pesesse, X.; De Smedt, F.; Woscholski, R.; Parker, P.; Erneux, C.
Cloning and expression of a human placenta inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase
Biochem. Biophys. Res. Commun.
225
243-249
1996
Homo sapiens
Drayer, A.; Pesesse, X.; De Smedt, F.; Communi, D.; Moreau, C.; Erneux, C.
The family of inositol and phosphatidylinositol polyphosphate 5-phosphatases
Biochem. Soc. Trans.
24
1001-1005
1996
Homo sapiens, Rattus norvegicus
Wisniewski, D.; Strife, A.; Swendeman, S.; Erdjument-Bromage, H.; Geromanos, S.; Kavanaugh, W.M.; Tempst, P.; Clarkson, B.
A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells
Blood
93
2707-2720
1999
Homo sapiens (O15357), Homo sapiens (Q92835)
Zwaenepoel, K.; Goris, J.; Erneux, C.; Parker, P.J.; Janssens, V.
Protein phosphatase 2A PR130/Balpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling
FASEB J.
24
538-547
2010
Homo sapiens
Paternotte, N.; Zhang, J.; Vandenbroere, I.; Backers, K.; Blero, D.; Kioka, N.; Vanderwinden, J.M.; Pirson, I.; Erneux, C.
SHIP2 interaction with the cytoskeletal protein Vinexin
FEBS J.
272
6052-6066
2005
Mus musculus
Pesesse, X.; Moreau, C.; Drayer, A.L.; Woscholski, R.; Parker, P.; Erneux, C.
The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity
FEBS Lett.
437
301-303
1998
Homo sapiens
Lioubin, M.N.; Algate, P.A.; Tsai, S.; Carlberg, K.; Aebersold, A.; Rohrschneider, L.R.
p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity
Genes Dev.
10
1084-95
1996
Homo sapiens
Woscholski, R.; Waterfield, M.D.; Parker, P.J.
Purification and biochemical characterization of a mammalian phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase
J. Biol. Chem.
270
31001-31007
1995
Rattus norvegicus
Giuriato, S.; Payrastre, B.; Drayer, A.L.; Plantavid, M.; Woscholski, R.; Parker, P.; Erneux, C.; Chap, H.
Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets
J. Biol. Chem.
272
26857-26863
1997
Homo sapiens
Woscholski, R.; Finan, P.M.; Radley, E.; Totty, N.F.; Sterling, A.E.; Hsuan, J.J.; Waterfield, M.D.; Parker, P.J.
Synaptojanin is the major constitutively active phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase in rodent brain
J. Biol. Chem.
272
9625-9628
1997
Rattus norvegicus
Pesesse, X.; Dewaste, V.; De Smedt, F.; Laffargue, M.; Giuriato, S.; Moreau, C.; Payrastre, B.; Erneux, C.
The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cells
J. Biol. Chem.
276
28348-28355
2001
Homo sapiens
Ooms, L.M.; Dyson, J.M.; Kong, A.M.; Mitchell, C.A.
Analysis of phosphatidylinositol 3,4,5 trisphosphate 5-phosphatase activity by in vitro and in vivo assays
Methods Mol. Biol.
462
223-239
2009
Chlorocebus aethiops
Damen, J.E.; Liu, L.; Rosten, P.; Humphries, R.K.; Jefferson, A.B.; Majerus, P.W.; Krystal, G.
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
Proc. Natl. Acad. Sci. USA
93
1689-1693
1996
Mus musculus
Kuehbacher, A.; Dambournet, D.; Echard, A.; Cossart, P.; Pizarro-Cerda, J.
Phosphatidylinositol 5-phosphatase oculocerebrorenal syndrome of Lowe protein (OCRL) controls actin dynamics during early steps of Listeria monocytogenes infection
J. Biol. Chem.
287
13128-13136
2012
Danio rerio
Ijuin, T.; Takenawa, T.
Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP)
J. Biol. Chem.
287
6991-6999
2012
Mus musculus
Tu, W.J.; Liu, X.Y.; Dong, H.; Yu, Y.; Wang, Y.; Chen, H.
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1: a meaningful and independent marker to predict stroke in the Chinese population
J. Mol. Neurosci.
52
507-514
2014
Homo sapiens
Ramos, A.R.; Elong Edimo, W.; Erneux, C.
Phosphoinositide 5-phosphatase activities control cell motility in glioblastoma Two phosphoinositides PI(4,5)P2 and PI(3,4)P2 are involved
Adv. Biol. Regul.
67
40-48
2018
Homo sapiens (O15357)
Gorgani-Firuzjaee, S.; Adeli, K.; Meshkani, R.
Inhibition of SH2-domain-containing inositol 5-phosphatase (SHIP2) ameliorates palmitate induced-apoptosis through regulating Akt/FOXO1 pathway and ROS production in HepG2 cells
Biochem. Biophys. Res. Commun.
464
441-446
2015
Homo sapiens (O15357)
Eramo, M.J.; Mitchell, C.A.
Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases
Biochem. Soc. Trans.
44
240-252
2016
Homo sapiens (O15357), Homo sapiens (Q92835)
Russo, C.M.; Adhikari, A.A.; Wallach, D.R.; Fernandes, S.; Balch, A.N.; Kerr, W.G.; Chisholm, J.D.
Synthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5-phosphatase (SHIP)
Bioorg. Med. Chem. Lett.
25
5344-5348
2015
Homo sapiens (Q92835)
Thomas, M.P.; Erneux, C.; Potter, B.V.
SHIP2 structure, function and inhibition
ChemBioChem
18
233-247
2017
Homo sapiens (O15357)
Le Coq, J.; Camacho-Artacho, M.; Velazquez, J.V.; Santiveri, C.M.; Gallego, L.H.; Campos-Olivas, R.; Doelker, N.; Lietha, D.
Structural basis for interdomain communication in SHIP2 providing high phosphatase activity
eLife
6
e26640
2017
Homo sapiens (O15357)
Gorgani-Firuzjaee, S.; Meshkani, R.
SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells
Free Radic. Biol. Med.
89
679-689
2015
Homo sapiens (O15357)
Rajadurai, C.V.; Havrylov, S.; Coelho, P.P.; Ratcliffe, C.D.; Zaoui, K.; Huang, B.H.; Monast, A.; Chughtai, N.; Sangwan, V.; Gertler, F.B.; Siegel, P.M.; Park, M.
5-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion
J. Cell Biol.
214
719-734
2016
Homo sapiens (O15357)
Elong Edimo, W.; Ghosh, S.; Derua, R.; Janssens, V.; Waelkens, E.; Vanderwinden, J.M.; Robe, P.; Erneux, C.
SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells
J. Cell Sci.
129
1101-1114
2016
Homo sapiens (O15357)
Ghosh, S.; Scozzaro, S.; Ramos, A.R.; Delcambre, S.; Chevalier, C.; Krejci, P.; Erneux, C.
Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cells
J. Cell Sci.
131
jcs216408
2018
Homo sapiens (O15357)
Cestari, I.; McLeland-Wieser, H.; Stuart, K.
Nuclear phosphatidylinositol 5-phosphatase is essential for allelic exclusion of variant surface glycoprotein genes in trypanosomes
Mol. Cell. Biol.
39
e00395-18
2019
Trypanosoma brucei
Dempke, W.C.M.; Uciechowski, P.; Fenchel, K.; Chevassut, T.
Targeting SHP-1, 2 and SHIP pathways a novel strategy for cancer treatment?
Oncology
95
257-269
2018
Homo sapiens (O15357), Homo sapiens (Q92835)
Hoekstra, E.; Das, A.M.; Willemsen, M.; Swets, M.; Kuppen, P.J.; van der Woude, C.J.; Bruno, M.J.; Shah, J.P.; Ten Hagen, T.L.; Chisholm, J.D.; Kerr, W.G.; Peppelenbosch, M.P.; Fuhler, G.M.
Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation
Oncotarget
7
73525-73540
2016
Homo sapiens (O15357)
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