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Reference on EC 3.1.3.53 - [myosin-light-chain] phosphatase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sobieszek, A.; Borkowski, J.; Babiychuk, V.S.
Purification and characterization of a smooth muscle myosin light chain kinase-phosphatase complex
J. Biol. Chem.
272
7034-7041
1997
Meleagris gallopavo
Manually annotated by BRENDA team
Pato, M.D.; Adelstein, R.S.
Purification and characterization of a multisubunit phosphatase from turkey gizzard smooth muscle. The effect of calmodulin binding to myosin light chain kinase on dephosphorylation
J. Biol. Chem.
258
7047-7054
1983
Meleagris gallopavo
Manually annotated by BRENDA team
Houston, M.E.; Lingley, M.D.; Stuart, D.S.; Grange, R.W.
Myosin light chain phosphorylation in intact human muscle
FEBS Lett.
219
469-471
1987
Homo sapiens
Manually annotated by BRENDA team
Pato, M.D.; Kerc, E.
Purification of smooth muscle myosin phosphatase from turkey gizzard
Methods Enzymol.
159
446-453
1988
Meleagris gallopavo
Manually annotated by BRENDA team
Shimizu, H.; Ito, M.; Miyahara, M.; Ichikawa, K.; Okubo, S.; Konishi, T.; Naka, M.; Tanaka, T.; Hirano, K.; Hartshorne, D.J.; Nakano, T.
Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase
J. Biol. Chem.
269
30407-30411
1994
Gallus gallus
Manually annotated by BRENDA team
Chisholm, A.A.K.; Cohen, P.
The myosin-bound form of protein phosphatase 1 (PP-1M) is the enzyme that dephosphorylates native myosin in skeletal and cardiac muscles
Biochim. Biophys. Acta
971
163-169
1988
Bos taurus, Oryctolagus cuniculus
Manually annotated by BRENDA team
Alessi, D.; MacDougall, L.K.; Sola, M.M.; Ikebe, M.; Cohen, P.
The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1
Eur. J. Biochem.
210
1023-1035
1992
Gallus gallus, Gallus gallus PP-1
Manually annotated by BRENDA team
Sato, O.; Ogawa, Y.
Myosin assembly critical for the enzyme activity of smooth muscle myosin phosphatase: Effects of MgATP, ionic strength, and Mg2+
J. Biochem.
129
881-889
2001
Gallus gallus
Manually annotated by BRENDA team
Hirano, M.; Niiro, N.; Hirano, K.; Nishimura, J.; Hartshorne, D.J.; Kanaide, H.
Expression, subcellular localization, and cloning of the 130-kDa regulatory subunit of myosin phosphatase in porcine aortic endothelial cells
Biochem. Biophys. Res. Commun.
254
490-496
1999
Sus scrofa (Q9TV77), Sus scrofa
Manually annotated by BRENDA team
Zhang, Y.; Mabuchi, K.; Tao, T.
Expression in insect cells and characterization of the 110 kDa anchoring subunit of myosin light chain phosphatase
Biochim. Biophys. Acta
1343
51-58
1997
Gallus gallus, Gallus gallus MLCP
Manually annotated by BRENDA team
Schmidt, U.S.; Troschka, M.; Pfitzer, G.
The variable coupling between force and myosin light chain phosphorylation in Triton-skinned chicken gizzard fibre bundles: Role of myosin light chain phosphatase
Pflugers Arch.
429
708-715
1995
Gallus gallus
Manually annotated by BRENDA team
Kitazawa, T.; Eto, M.; Woodsome, T.P.; Khalequzzaman, M.
Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle
J. Physiol.
546
879-889
2003
Oryctolagus cuniculus
Manually annotated by BRENDA team
Ito, M.; Feng, J.; Tsujino, S.; Inagaki, N.; Inagaki, M.; Tanaka, J.; Ichikawa, K.; Hartshorne, D.J.; Nakano, T.
Interaction of smooth muscle myosin phosphatase with phospholipids
Biochemistry
36
7607-7614
1997
Gallus gallus, Rattus norvegicus
Manually annotated by BRENDA team
Gailly, P.; Wu, X.; Haystead, T.A.J.; Somlyo, A.P.; Cohen, P.T.W.; Cohen, P.; Somlyo, A.V.
Regions of the 110-kDa regulatory subunit M110 required for regulation of myosin-light-chain-phosphatase activity in smooth muscle
Eur. J. Biochem.
239
326-332
1996
Rattus norvegicus, Sus scrofa, Sus scrofa SMPP-1M
Manually annotated by BRENDA team
Belik, J.; Majumdar, R.; Fabris, V.E.; Kerc, E.; Pato, M.D.
Myosin light chain phosphatase and kinase abnormalities in fetal sheep pulmonary hypertension
Pediatr. Res.
43
57-61
1998
Ovis aries
Manually annotated by BRENDA team
Richards, C.T.; Ogut, O.; Brozovich, F.V.
Agonist-induced force enhancement. The role of isoforms and phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase
J. Biol. Chem.
277
4422-4427
2002
Gallus gallus
Manually annotated by BRENDA team
Langsetmo, K.; Stafford, W.F., 3rd; Mabuchi, K.; Tao, T.
Recombinant small subunit of smooth muscle myosin light chain phosphatase. Molecular properties and interactions with the targeting subunit
J. Biol. Chem.
276
34318-34322
2001
Gallus gallus, Gallus gallus PP-1M
Manually annotated by BRENDA team
Etter, E.F.; Eto, M.; Wardle, R.L.; Brautigan, D.L.; Murphy, R.A.
Activation of myosin light chain phosphatase in intact arterial smooth muscle during nitric oxide-induced relaxation
J. Biol. Chem.
276
34681-34685
2001
Sus scrofa
Manually annotated by BRENDA team
Ikebe, R.; Reardon, S.; Mitsui, T.; Ikebe, M.
Role of the N-terminal region of the regulatory light chain in the dephosphorylation of myosin by myosin light chain phosphatase
J. Biol. Chem.
274
30122-30126
1999
Meleagris gallopavo, Meleagris gallopavo MLCP
Manually annotated by BRENDA team
Muranyi, A.; Erdodi, F.; Ito, M.; Gergely, P.; Hartshorne, D.J.
Identification and localization of myosin phosphatase in human platelets
Biochem. J.
330
225-231
1998
Homo sapiens
-
Manually annotated by BRENDA team
Niiro, N.; Koga, Y.; Ikebe, M.
Agonist-induced changes in the phosphorylation of the myosin-binding subunit of myosin light chain phosphatase and CPI17, two regulatory factors of myosin light chain phosphatase, in smooth muscle
Biochem. J.
369
117-128
2003
Oryctolagus cuniculus, Rattus norvegicus
Manually annotated by BRENDA team
Essler, M.; Amano, M.; Kruse, H.J.; Kaibuchi, K.; Weber, P.C.; Aepfelbacher, M.
Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells
J. Biol. Chem.
273
21867-21874
1998
Homo sapiens
Manually annotated by BRENDA team
Hirano, K.; Phan, B.C.; Hartshorne, D.J.
Interactions of the subunits of smooth muscle myosin phosphatase
J. Biol. Chem.
272
3683-3688
1997
Gallus gallus, Meleagris gallopavo
Manually annotated by BRENDA team
Arimura, T.; Suematsu, N.; Zhou, Y.B.; Nishimura, J.; Satoh, S.; Takeshita, A.; Kanaide, H.; Kimura, A.
Identification, characterization, and functional analysis of heart-specific myosin light chain phosphatase small subunit
J. Biol. Chem.
276
6073-6082
2001
Homo sapiens (O60237)
Manually annotated by BRENDA team
Parizi, M.; Howard, E.W.; Tomasek, J.J.
Regulation of LPA-promoted myofibroblast contraction: Role of Rho, myosin light chain kinase, and myosin light chain phosphatase
Exp. Cell Res.
254
210-220
2000
Homo sapiens
Manually annotated by BRENDA team
Hartshorne, D.J.
Myosin phosphatase: Subunits and interactions
Acta Physiol. Scand.
164
483-493
1998
Gallus gallus, Homo sapiens
Manually annotated by BRENDA team
Payne, M.C.; Zhang, H.Y.; Shirasawa, Y.; Koga, Y.; Ikebe, M.; Benoit, J.N.; Fisher, S.A.
Dynamic changes in expression of myosin phosphatase in a model of portal hypertension
Am. J. Physiol.
286
H1801-H1810
2004
Rattus norvegicus
Manually annotated by BRENDA team
Belik, J.; Kerc, E.; Pato, M.D.
Rat pulmonary arterial smooth muscle myosin light chain kinase and phosphatase activities decrease with age
Am. J. Physiol.
290
L509-516
2006
Rattus norvegicus
Manually annotated by BRENDA team
Karim, S.M.; Rhee, A.Y.; Given, A.M.; Faulx, M.D.; Hoit, B.D.; Brozovich, F.V.
Vascular reactivity in heart failure: role of myosin light chain phosphatase
Circ. Res.
95
612-618
2004
Rattus norvegicus
Manually annotated by BRENDA team
Lubomirov, L.T.; Reimann, K.; Metzler, D.; Hasse, V.; Stehle, R.; Ito, M.; Hartshorne, D.J.; Gagov, H.; Pfitzer, G.; Schubert, R.
Urocortin-induced decrease in Ca2+ sensitivity of contraction in mouse tail arteries is attributable to cAMP-dependent dephosphorylation of MYPT1 and activation of myosin light chain phosphatase
Circ. Res.
98
1159-1167
2006
Mus musculus
Manually annotated by BRENDA team
Xia, D.; Stull, J.T.; Kamm, K.E.
Myosin phosphatase targeting subunit 1 affects cell migration by regulating myosin phosphorylation and actin assembly
Exp. Cell Res.
304
506-517
2005
Homo sapiens
Manually annotated by BRENDA team
Goeckeler, Z.M.; Wysolmerski, R.B.
Myosin phosphatase and cofilin mediate cAMP/cAMP-dependent protein kinase-induced decline in endothelial cell isometric tension and myosin II regulatory light chain phosphorylation
J. Biol. Chem.
280
33083-33095
2005
Bos taurus
Manually annotated by BRENDA team
Koga, Y.; Ikebe, M.
p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA
J. Biol. Chem.
280
4983-4991
2005
Rattus norvegicus
Manually annotated by BRENDA team
Lontay, B.; Serfozo, Z.; Gergely, P.; Ito, M.; Hartshorne, D.J.; Erdodi, F.
Localization of myosin phosphatase target subunit 1 in rat brain and in primary cultures of neuronal cells
J. Comp. Neurol.
478
72-87
2004
Rattus norvegicus
Manually annotated by BRENDA team
Payne, M.C.; Zhang, H.Y.; Prosdocimo, T.; Joyce, K.M.; Koga, Y.; Ikebe, M.; Fisher, S.A.
Myosin phosphatase isoform switching in vascular smooth muscle development
J. Mol. Cell. Cardiol.
40
274-282
2006
Rattus norvegicus
Manually annotated by BRENDA team
Wu, Y.; Muranyi, A.; Erdodi, F.; Hartshorne, D.J.
Localization of myosin phosphatase target subunit and its mutants
J. Muscle Res. Cell Motil.
26
123-134
2005
Gallus gallus, Homo sapiens
Manually annotated by BRENDA team
Wardle, R.L.; Gu, M.; Ishida, Y.; Paul, R.J.
Ca2+-desensitizing hypoxic vasorelaxation: pivotal role for the myosin binding subunit of myosin phosphatase (MYPT1) in porcine coronary artery
J. Physiol.
572
259-267
2006
Sus scrofa
Manually annotated by BRENDA team
Lu, Y.; Zhang, H.; Gokina, N.I.; Mandala, M.; Sato, O.; Ikebe, M.; Osol, G.; Fisher, S.A.
Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy
Am. J. Physiol. Cell Physiol.
294
C564-C571
2008
Rattus norvegicus
Manually annotated by BRENDA team
Matsumura, F.; Hartshorne, D.J.
Myosin phosphatase target subunit: Many roles in cell function
Biochem. Biophys. Res. Commun.
369
149-56
2007
Mammalia
Manually annotated by BRENDA team
Okamoto, R.; Kato, T.; Mizoguchi, A.; Takahashi, N.; Nakakuki, T.; Mizutani, H.; Isaka, N.; Imanaka-Yoshida, K.; Kaibuchi, K.; Lu, Z.; Mabuchi, K.; Tao, T.; Hartshorne, D.J.; Nakano, T.; Ito, M.
Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart
Cell. Signal.
18
1408-1416
2006
Mammalia
Manually annotated by BRENDA team
Jeon, S.B.; Kim, G.; Kim, J.I.; Seok, Y.M.; Kim, S.H.; Suk, K.; Shin, H.M.; Lee, Y.H.; Kim, I.K.
Flavone inhibits vascular contraction by decreasing phosphorylation of the myosin phosphatase target subunit
Clin. Exp. Pharmacol. Physiol.
34
1116-1120
2007
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Manually annotated by BRENDA team
Mitonaka, T.; Muramatsu, Y.; Sugiyama, S.; Mizuno, T.; Nishida, Y.
Essential roles of myosin phosphatase in the maintenance of epithelial cell integrity of Drosophila imaginal disc cells
Dev. Biol.
309
78-86
2007
Drosophila melanogaster
Manually annotated by BRENDA team
Parra, M.; Mahmoudi, T.; Verdin, E.
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes
Genes Dev.
21
638-643
2007
Mus musculus, Mus musculus BALB/c
Manually annotated by BRENDA team
Kirchner, J.; Gross, S.; Bennett, D.; Alphey, L.
The nonmuscle myosin phosphatase PP1beta (flapwing) negatively regulates Jun N-terminal kinase in wing imaginal discs of Drosophila
Genetics
175
1741-1749
2007
Drosophila melanogaster
Manually annotated by BRENDA team
Lee, E.; Hayes, D.B.; Langsetmo, K.; Sundberg, E.J.; Tao, T.C.
Interactions between the leucine-zipper motif of cGMP-dependent protein kinase and the C-terminal region of the targeting subunit of myosin light chain phosphatase
J. Mol. Biol.
373
1198-1212
2007
Homo sapiens
Manually annotated by BRENDA team
Azam, M.A.; Yoshioka, K.; Ohkura, S.; Takuwa, N.; Sugimoto, N.; Sato, K.; Takuwa, Y.
Ca2+-independent, inhibitory effects of cyclic adenosine 5-monophosphate on Ca2+ regulation of phosphoinositide 3-kinase C2alpha, Rho, and myosin phosphatase in vascular smooth muscle
J. Pharmacol. Exp. Ther.
320
907-916
2007
Oryctolagus cuniculus
Manually annotated by BRENDA team
Watanabe, T.; Hosoya, H.; Yonemura, S.
Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells
Mol. Biol. Cell
18
605-616
2007
Canis lupus familiaris, Canis lupus familiaris Madin Darby
Manually annotated by BRENDA team
Koga, Y.; Ikebe, M.
A novel regulatory mechanism of myosin light chain phosphorylation via binding of 14-3-3 to myosin phosphatase
Mol. Biol. Cell
19
1062-1071
2007
Rattus norvegicus
Manually annotated by BRENDA team
Eto, M.; Kitazawa, T.; Matsuzawa, F.; Aikawa, S.; Kirkbride, J.A.; Isozumi, N.; Nishimura, Y.; Brautigan, D.L.; Ohki, S.
Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor
Structure
15
1591-1602
2007
Sus scrofa
Manually annotated by BRENDA team
Tomasek, J.J.; Vaughan, M.B.; Kropp, B.P.; Gabbiani, G.; Martin, M.D.; Haaksma, C.J.; Hinz, B.
Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity
Wound Repair Regen.
14
313-320
2006
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Manually annotated by BRENDA team
Mizuno, Y.; Isotani, E.; Huang, J.; Ding, H.; Stull, J.T.; Kamm, K.E.
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo
Am. J. Physiol. Cell Physiol.
295
C358-C364
2008
Homo sapiens
Manually annotated by BRENDA team
Sharma, A.K.; Zhou, G.P.; Kupferman, J.; Surks, H.K.; Christensen, E.N.; Chou, J.J.; Mendelsohn, M.E.; Rigby, A.C.
Probing the interaction between the coiled-coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C-terminus of the myosin binding subunit of the myosin light chain phosphatase
J. Biol. Chem.
283
32860-32869
2008
Homo sapiens
Manually annotated by BRENDA team
Wang, Y.; Zheng, X.R.; Riddick, N.; Bryden, M.; Baur, W.; Zhang, X.; Surks, H.K.
ROCK isoform regulation of myosin phosphatase and contractility in vascular smooth muscle cells
Circ. Res.
104
531-540
2009
Rattus norvegicus
Manually annotated by BRENDA team
Ogut, O.; Brozovich, F.V.
The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure
J. Cell. Mol. Med.
12
2158-2164
2008
Homo sapiens
Manually annotated by BRENDA team
Ratz, P.H.; Miner, A.S.
Role of protein kinase Czeta and calcium entry in KCl-induced vascular smooth muscle calcium sensitization and feedback control of cellular calcium levels
J. Pharmacol. Exp. Ther.
328
399-408
2009
Oryctolagus cuniculus
Manually annotated by BRENDA team
Borman, M.A.; Freed, T.A.; Haystead, T.A.; Macdonald, J.A.
The role of the calponin homology domain of smoothelin-like 1 (SMTNL1) in myosin phosphatase inhibition and smooth muscle contraction
Mol. Cell. Biochem.
327
93-100
2009
Oryctolagus cuniculus
Manually annotated by BRENDA team
Webb, J.D.; Muranyi, A.; Pugh, C.W.; Ratcliffe, P.J.; Coleman, M.L.
MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)
Biochem. J.
420
327-333
2009
Homo sapiens, Meleagris gallopavo
Manually annotated by BRENDA team
Kiss, A.; Lontay, B.; Becsi, B.; Markasz, L.; Olah, E.; Gergely, P.; Erdodi, F.
Myosin phosphatase interacts with and dephosphorylates the retinoblastoma protein in THP-1 leukemic cells: its inhibition is involved in the attenuation of daunorubicin-induced cell death by calyculin-A
Cell. Signal.
20
2059-2070
2008
Homo sapiens
Manually annotated by BRENDA team
Umeda, D.; Yamada, K.; Tachibana, H.
H89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) induces reduction of myosin regulatory light chain phosphorylation and inhibits cell proliferation
Eur. J. Pharmacol.
590
61-66
2008
Homo sapiens
Manually annotated by BRENDA team
Khromov, A.; Choudhury, N.; Stevenson, A.S.; Somlyo, A.V.; Eto, M.
Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction
J. Biol. Chem.
284
21569-21579
2009
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Mori, S.; Iwaoka, R.; Eto, M.; Ohki, S.
Solution structure of the inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1
Proteins
77
732-735
2009
Homo sapiens (O14974)
Manually annotated by BRENDA team
Cole, W.C.; Welsh, D.G.
Role of myosin light chain kinase and myosin light chain phosphatase in the resistance arterial myogenic response to intravascular pressure
Arch. Biochem. Biophys.
510
160-173
2011
Rattus norvegicus
Manually annotated by BRENDA team
Matsumura, F.; Yamakita, Y.; Yamashiro, S.
Myosin light chain kinases and phosphatase in mitosis and cytokinesis
Arch. Biochem. Biophys.
510
76-82
2011
Homo sapiens
Manually annotated by BRENDA team
Okada, C.; Nakamura, A.; Tomioka, S.; Kohama, K.; Kaneko, T.S.
Purification and characterization of the plasmodial phosphatase that hydrolyses the phosphorylated light chain of Physarum myosin II from Physarum polycephalum
Cell Biol. Int.
34
827-835
2010
Physarum polycephalum
Manually annotated by BRENDA team
Sun, Y.; Yan, Y.; Denef, N.; Schuepbach, T.
Regulation of somatic myosin activity by protein phosphatase 1beta controls Drosophila oocyte polarization
Development
138
1991-2001
2011
Drosophila melanogaster
Manually annotated by BRENDA team
Shichi, D.; Arimura, T.; Ishikawa, T.; Kimura, A.
Heart-specific small subunit of myosin light chain phosphatase activates rho-associated kinase and regulates phosphorylation of myosin phosphatase target subunit 1
J. Biol. Chem.
285
33680-33690
2010
Homo sapiens
Manually annotated by BRENDA team
Scotto-Lavino, E.; Garcia-Diaz, M.; Du, G.; Frohman, M.A.
Basis for the isoform-specific interaction of myosin phosphatase subunits protein phosphatase 1c beta and myosin phosphatase targeting subunit 1
J. Biol. Chem.
285
6419-6424
2010
Homo sapiens
Manually annotated by BRENDA team
Kim, K.M.; Csortos, C.; Czikora, I.; Fulton, D.; Umapathy, N.S.; Olah, G.; Verin, A.D.
Molecular characterization of myosin phosphatase in endothelium
J. Cell. Physiol.
227
1701-1708
2012
Homo sapiens
Manually annotated by BRENDA team
Lee, J.H.; Palaia, T.; Ragolia, L.
Impaired insulin-stimulated myosin phosphatase Rho-interacting protein signaling in diabetic Goto-Kakizaki vascular smooth muscle cells
Am. J. Physiol. Cell Physiol.
302
C1371-C1381
2012
Rattus norvegicus
Manually annotated by BRENDA team
Khasnis, M.; Nakatomi, A.; Gumpper, K.; Eto, M.
Reconstituted human myosin light chain phosphatase reveals distinct roles of two inhibitory phosphorylation sites of the regulatory subunit, MYPT1
Biochemistry
53
2701-2709
2014
Homo sapiens (O14974), Homo sapiens
Manually annotated by BRENDA team
Ryan, T.; Shelton, M.; Lambert, J.P.; Malecova, B.; Boisvenue, S.; Ruel, M.; Figeys, D.; Puri, P.L.; Skerjanc, I.S.
Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway
Circ. Res.
112
257-266
2013
Homo sapiens
Manually annotated by BRENDA team
Majumder, P.; Aranjuez, G.; Amick, J.; McDonald, J.A.
Par-1 controls myosin-II activity through myosin phosphatase to regulate border cell migration
Curr. Biol.
22
363-372
2012
Drosophila melanogaster
Manually annotated by BRENDA team
Qiao, Y.N.; He, W.Q.; Chen, C.P.; Zhang, C.H.; Zhao, W.; Wang, P.; Zhang, L.; Wu, Y.Z.; Yang, X.; Peng, Y.J.; Gao, J.M.; Kamm, K.E.; Stull, J.T.; Zhu, M.S.
Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure
J. Biol. Chem.
289
22512-22523
2014
Mus musculus (Q9DBR7)
Manually annotated by BRENDA team
Iwasaki, T.; Katayama, T.; Kohama, K.; Endo, Y.; Sawasaki, T.
Myosin phosphatase is inactivated by caspase-3 cleavage and phosphorylation of myosin phosphatase targeting subunit 1 during apoptosis
Mol. Biol. Cell
24
748-756
2013
Homo sapiens (O14974), Mus musculus (Q9DBR7)
Manually annotated by BRENDA team
Jayashankar, V.; Nguyen, M.J.; Carr, B.W.; Zheng, D.C.; Rosales, J.B.; Rosales, J.B.; Weiser, D.C.
Protein phosphatase 1 beta paralogs encode the zebrafish myosin phosphatase catalytic subunit
PLoS ONE
8
e75766
2013
Danio rerio
Manually annotated by BRENDA team
Sutherland, C.; MacDonald, J.A.; Walsh, M.P.
Analysis of phosphorylation of the myosin-targeting subunit of myosin light chain phosphatase by Phos-tag SDS-PAGE
Am. J. Physiol. Cell Physiol.
310
C681-C691
2016
Rattus norvegicus, Gallus gallus (Q90623)
Manually annotated by BRENDA team
Reho, J.J.; Kenchegowda, D.; Asico, L.D.; Fisher, S.A.
A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading
Am. J. Physiol. Heart Circ. Physiol.
310
H1715-H1724
2016
Mus musculus (Q9DBR7)
Manually annotated by BRENDA team
Arimura, T.; Muchir, A.; Kuwahara, M.; Morimoto, S.; Ishikawa, T.; Du, C.K.; Zhan, D.Y.; Nakao, S.; Machida, N.; Tanaka, R.; Yamane, Y.; Hayashi, T.; Kimura, A.
Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance
Am. J. Physiol. Heart Circ. Physiol.
314
H1192-H1202
2018
Mus musculus
Manually annotated by BRENDA team
Horvath, D.; Sipos, A.; Major, E.; Konya, Z.; Batori, R.; Dedinszki, D.; Szoell Si, A.; Tamas, I.; Ivan, J.; Kiss, A.; Erd di, F.; Lontay, B.
Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin
Biochim. Biophys. Acta
1864
3268-3280
2018
Homo sapiens (O14974), Homo sapiens, Mus musculus (Q9DBR7), Mus musculus
Manually annotated by BRENDA team
Shibata, K.; Sakai, H.; Huang, Q.; Kamata, H.; Chiba, Y.; Misawa, M.; Ikebe, R.; Ikebe, M.
Rac1 regulates myosin II phosphorylation through regulation of myosin light chain phosphatase
J. Cell. Physiol.
230
1352-1364
2015
Rattus norvegicus (Q10728)
Manually annotated by BRENDA team
Chen, C.; Chen, X.; Qiao, Y.; Wang, P.; He, W.; Zhang, C.; Zhao, W.; Gao, Y.; Chen, C.; Tao, T.; Sun, J.; Wang, Y.; Gao, N.; Kamm, K.; Stull, J.; Zhu, M.
In vivo roles for myosin phosphatase targeting subunit-1 phosphorylation sites T694 and T852 in bladder smooth muscle contraction
J. Physiol.
593
681-700
2015
Mus musculus (Q9DBR7), Mus musculus
Manually annotated by BRENDA team
Zheng, X.; Heaps, C.; Fisher, S.
Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion
Microvasc. Res.
98
166-171
2015
Sus scrofa
Manually annotated by BRENDA team
Valencia-Exposito, A.; Grosheva, I.; Miguez, D.G.; Gonzalez-Reyes, A.; Martin-Bermudo, M.D.
Myosin light-chain phosphatase regulates basal actomyosin oscillations during morphogenesis
Nat. Commun.
7
10746
2016
Drosophila melanogaster
Manually annotated by BRENDA team
Bremer, J.; Granato, M.
Myosin phosphatase fine-tunes zebrafish motoneuron position during axonogenesis
PLoS Genet.
12
e1006440
2016
Danio rerio (Z4YIS0)
-
Manually annotated by BRENDA team
Lee, E.; Stafford, W.3.
Interaction of myosin phosphatase target subunit (MYPT1) with myosin phosphatase-RhoA interacting protein (MRIP) a role of glutamic acids in the interaction
PLoS One
10
e0139875
2015
Homo sapiens (O14974)
Manually annotated by BRENDA team
Lartey, J.; Taggart, J.; Robson, S.; Taggart, M.
Altered expression of human smooth muscle myosin phosphatase targeting (MYPT) isovariants with pregnancy and labor
PLoS ONE
11
e0164352
2016
Homo sapiens (O14974), Homo sapiens
Manually annotated by BRENDA team