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(N'-amidino)streptidine phosphate + H2O
(N'-amidino)streptidine + phosphate
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Substrates: -
Products: -
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1,3-diamino-1,3-dideoxy-scyllo-inositol + dihydrostreptomycin 6-phosphate
?
-
Substrates: -
Products: -
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1,3-diamino-1,3-dideoxy-scyllo-inositol + p-nitrophenyl phosphate
?
-
Substrates: -
Products: -
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2-deoxystreptamine + dihydrostreptomycin 6-phosphate
?
-
Substrates: -
Products: -
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2-deoxystreptamine + p-nitrophenyl phosphate
?
-
Substrates: -
Products: -
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dihydrostreptomycin 3'',6-bisphosphate + H2O
dihydrostreptomycin 3''-phosphate + phosphate
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Substrates: -
Products: -
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dihydrostreptomycin 6-phosphate
dihydrostreptomycin + phosphate
dihydrostreptomycin 6-phosphate + H2O
dihydrostreptomycin + phosphate
ethanolamine phosphate + H2O
?
N-amidinostreptamine phosphate + H2O
N-amidinostreptamine + phosphate
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Substrates: -
Products: -
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N1-amidinostreptamine 6-phosphate + H2O
N1-amidinostreptamine + phosphate
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Substrates: -
Products: -
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O-phosphoryl-Tris + H2O
?
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Substrates: slow hydrolysis
Products: -
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p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
streptidine 6-phosphate + H2O
dihydrostreptomycin + phosphate
streptomycin 6-phosphate + H2O
streptomycin + phosphate
streptomycin-3''-phosphate + H2O
streptomycin + phosphate
additional information
?
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dihydrostreptomycin 6-phosphate
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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dihydrostreptomycin 6-phosphate
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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dihydrostreptomycin 6-phosphate
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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dihydrostreptomycin 6-phosphate
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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dihydrostreptomycin 6-phosphate + H2O
dihydrostreptomycin + phosphate
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Substrates: final step in streptomycin biosynthesis
Products: -
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dihydrostreptomycin 6-phosphate + H2O
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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ethanolamine phosphate + H2O
?
-
Substrates: -
Products: -
?
ethanolamine phosphate + H2O
?
-
Substrates: -
Products: -
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ethanolamine phosphate + H2O
?
-
Substrates: -
Products: -
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ethanolamine phosphate + H2O
?
-
Substrates: -
Products: -
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
Substrates: -
Products: -
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
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Substrates: -
Products: -
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p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
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Substrates: -
Products: -
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p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
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Substrates: -
Products: -
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streptidine 6-phosphate + H2O
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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streptidine 6-phosphate + H2O
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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streptidine 6-phosphate + H2O
dihydrostreptomycin + phosphate
-
Substrates: -
Products: -
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streptidine 6-phosphate + H2O
dihydrostreptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
?
streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin 6-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin-3''-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
?
streptomycin-3''-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
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streptomycin-3''-phosphate + H2O
streptomycin + phosphate
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Substrates: -
Products: -
?
streptomycin-3''-phosphate + H2O
streptomycin + phosphate
-
Substrates: -
Products: -
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Tris-phosphate + H2O
?
-
Substrates: -
Products: -
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Tris-phosphate + H2O
?
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Substrates: -
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Tris-phosphate + H2O
?
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Substrates: -
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Tris-phosphate + H2O
?
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Substrates: -
Products: -
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additional information
?
-
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Substrates: the enzyme and its gene might be involved in phosphate-regulation of the streptomycin-formation on both the gene and the enzyme levels
Products: -
?
additional information
?
-
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Substrates: the enzyme and its gene might be involved in phosphate-regulation of the streptomycin-formation on both the gene and the enzyme levels
Products: -
?
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Walker, M.S.; Walker, J.B.
Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate
J. Biol. Chem.
246
7034-7040
1971
Streptomyces sp.
brenda
Walker, J.B.
Streptomycin-6-P phosphohydrolase
Methods Enzymol.
43
465-470
1975
Streptomyces bikiniensis, Streptomyces galbus, Streptomyces griseocarneus, Streptomyces griseus
brenda
Sugiyama, M.; Mochizuki, H.; Nimi, O.; Nomi, R.
Assessment of competitive action of streptomycin 6-kinase and streptomycin 6-phosphatase in the in vitro protein synthesis of a streptomycin-producing microorganism
FEBS Lett.
139
331-333
1982
Streptomyces griseus, Streptomyces griseus HUT 6037
brenda
Walker, J.B.; Skorvaga, M.
Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6-phosphate to inosamines, streptamine, and 2-deoxystreptamine
J. Biol. Chem.
248
2441-2446
1973
Streptomyces bikiniensis
brenda
Distler, J.; Mansouri, K.; Mayer, G.; Stockmann, M.; Piepersberg, W.
Streptomycin biosynthesis and its regulation in Streptomycetes
Gene
115
105-111
1992
Streptomyces glaucescens, Streptomyces griseus
brenda
Mansouri, K.; Piepersberg, W.
Genetics of streptomycin production in Streptomyces griseus: nucleotide sequence of five genes, strFGHIK, including a phosphatase gene
Mol. Gen. Genet.
228
459-469
1991
Streptomyces griseus, Streptomyces lividans, Streptomyces lividans 66
brenda