Reference on EC 3.1.3.36 - phosphoinositide 5-phosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Matzaris, M.; Jackson, S.P.; Laxminarayan, K.M.; Speed, C.J.; Mitchell, C.A.
Identification and characterization of the phosphatidylinositol-(4,5)-bisphosphate 5-phosphatase in human platelets
J. Biol. Chem.
269
3397-33402
1994
Homo sapiens
Dawson, R.M.C.; Thompson, W.
The triphosphoinositide phosphomonoesterase of brain tissue
Biochem. J.
91
244-250
1964
Bos taurus
Mack, S.E.; Palmer, F.B.St.C.
Evidence for a specific phosphatidylinositol 4-phosphate phosphatase in human erythrocyte membranes
J. Lipid Res.
25
75-85
1984
Canis lupus familiaris, Homo sapiens, Oryctolagus cuniculus, Ovis aries, Platyrrhini, Rattus norvegicus
Mack, S.E.; Palmer, F.B.St.C.
Soluble and membrane-bound polyphosphoinositide phosphohydrolases in mammalian erythrocytes
Biochem. Cell Biol.
66
199-207
1988
Oryctolagus cuniculus, Ovis aries, Homo sapiens, Rattus norvegicus, Sus scrofa
Koutouzov, S.; Marche, P.
The Mg2+-activated phosphatidylinositol 4,5-bisphosphate-specific phosphomonoesterase of erythrocyte membrane
FEBS Lett.
144
16-20
1982
Rattus norvegicus
Roach, P.D.; Palmer, F.B.St.C.
Human erythrocyte cytosol phosphatidyl-inositol-bisphosphate phosphatase
Biochim. Biophys. Acta
661
323-333
1981
Homo sapiens
Palmer, F.B.St.C.
The phosphatidyl-myo-inositol-4,5-biphosphate phosphatase from Crithidia fasciculata
Can. J. Biochem.
59
469-476
1981
Crithidia fasciculata
Akhtar, R.A.; Abdel-Latif, A.A.
Studies on the properties of triphosphoinositide phosphomonoesterase and phosphodiesterase of rabbit iris smooth muscle
Biochim. Biophys. Acta
527
159-170
1978
Oryctolagus cuniculus
Whiting, P.H.; Palmano, K.P.; Hawthorne, J.N.
Enzymes of myo-inositol and inositol lipid metabolism in rats with streptozotocin-induced diabetes
Biochem. J.
179
549-553
1979
Rattus norvegicus
Sheltawy, A.; Brammer, M.; Borrill, D.
The subcellular distribution of triphosphoinositide phosphomonoesterase in guinea-pig brain
Biochem. J.
128
579-586
1972
Cavia porcellus
Cooper, P.H.; Hawthorne, J.N.
Phosphomonoesterase hydrolysis of polyphosphoinositides in rat kidney: Properties and subcellular localization of the enzyme system
Biochem. J.
150
537-551
1975
Rattus norvegicus
Lefebvre, Y.A.; White, D.A.; Hawthorne, J.N.
Diphosphoinositide metabolism in bovine adrenal medulla
Can. J. Biochem.
54
746-753
1976
Bos taurus
Abdel-Latif, A.; Akhtar, R.A.; Hawthorne, J.
Acetylcholine increases breakdown of triphosphoinositide of rabbit iris muscle prelabelled with phosphate
Biochem. J.
162
61-73
1977
Oryctolagus cuniculus
Sakisaka, T.; Itoh, T.; Miura, K.; Takenawa, T.
Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments
Mol. Cell. Biol.
17
3841-3849
1997
Bos taurus
Zhang, X.; Jefferson, A.B.; Auethavekiat, V.; Majerus, P.W.
The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase
Proc. Natl. Acad. Sci. USA
92
4853-4856
1995
Homo sapiens
Zhang, X.; Hartz, P.A.; Philip, E.; Racusen, L.C.; Majerus, P.W.
Cell lines from kidney proximal tubules of a patient with Lowe syndrome lack OCRL inositol polyphosphate 5-phosphatase and accumulate phosphatidylinositol 4,5-bisphosphate
J. Biol. Chem.
273
1574-1582
1998
Homo sapiens
Suchy, S.F.; Olivos-Glander, I.; Nussbaum, R.L.
Lowe syndrome, a deficiency of a phosphatidyl-inositol 4,5-bisphosphate 5-phosphatase in the Golgi apparatus
Hum. Mol. Genet.
4
2245-2250
1995
Homo sapiens
Palmer, F.B.S.C.
Enzymes that degrade phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate have different developmental profiles in chick brain
Biochem. Cell Biol.
68
800-803
1990
Gallus gallus
Palmer, F.B.S.C.; Theolis, R.; Cook, H.W.; Byers, D.M.
Purification of two immunologically related phosphatidylinositol-(4,5)-bisphosphate phosphatases from bovine brain cytosol
J. Biol. Chem.
269
3403-3410
1994
Bos taurus
Kong, A.M.; Speed, C.J.; O'Malley, C.J.; Layton, M.J.; Meehan, T.; Loveland, K.L.; Cheema, S.; Ooms, L.M.; Mitchell, C.A.
Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network
J. Biol. Chem.
275
24052-24064
2000
Mus musculus (Q9JII1)
Roschinger, W.; Muntau, A.C.; Rudolph, G.; Roscher, A.A.; Kammerer, S.
Carrier assessment in families with Lowe oculocerebrorenal syndrome: Novel mutations in the OCRL1 gene and correlation of direct DNA diagnosis with ocular examination
Mol. Genet. Metab.
69
213-222
2000
Homo sapiens
Johenning, F.W.; Wenk, M.R.; Uhlen, P.; Degray, B.; Lee, E.; De Camilli, P.; Ehrlich, B.E.
InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1
Biochem. J.
382
687-694
2004
Homo sapiens
Schmid, A.C.; Wise, H.M.; Mitchell, C.A.; Nussbaum, R.; Woscholski, R.
Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation
FEBS Lett.
576
9-13
2004
Homo sapiens, Mus musculus, Rattus norvegicus
Morales-Johansson, H.; Jenoe, P.; Cooke, F.T.; Hall, M.N.
Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4
J. Biol. Chem.
279
39604-39610
2004
Saccharomyces cerevisiae, Saccharomyces cerevisiae TB50
Chi, Y.; Zhou, B.; Wang, W.Q.; Chung, S.K.; Kwon, Y.U.; Ahn, Y.H.; Chang, Y.T.; Tsujishita, Y.; Hurley, J.H.; Zhang, Z.Y.
Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2
J. Biol. Chem.
279
44987-44995
2004
Schizosaccharomyces pombe
Zhong, R.; Burk, D.H.; Morrison, W.H., 3rd; Ye, Z.H.
FRAGILE FIBER3, an Arabidopsis gene encoding a type II inositol polyphosphate 5-phosphatase, is required for secondary wall synthesis and actin organization in fiber cells
Plant Cell
16
3242-3259
2004
Arabidopsis thaliana (Q84W55), Arabidopsis thaliana
Zhong, R.; Ye, Z.H.
Molecular and biochemical characterization of three WD-repeat-domain-containing inositol polyphosphate 5-phosphatases in Arabidopsis thaliana
Plant Cell Physiol.
45
1720-1728
2004
Arabidopsis thaliana (Q9SKB7), Arabidopsis thaliana
Buettner, R.; Ottinger, I.; Gerhardt-Salbert, C.; Wrede, C.E.; Schoelmerich, J.; Bollheimer, L.C.
Antisense oligonucleotides against the lipid phosphatase SHIP2 improve muscle insulin sensitivity in a dietary rat model of the metabolic syndrome
Am. J. Physiol. Endocrinol. Metab.
292
E1871-E1878
2007
Rattus norvegicus
Vinciguerra, M.; Foti, M.
PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
Arch. Physiol. Biochem.
112
89-104
2006
Chlorocebus aethiops, Cricetulus griseus, Mus musculus
Batty, I.H.; van der Kaay, J.; Gray, A.; Telfer, J.F.; Dixon, M.J.; Downes, C.P.
The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2
Biochem. J.
407
255-266
2007
Homo sapiens, Mus musculus (Q9JII1)
Andersen, J.F.; Ribeiro, J.M.
A secreted salivary inositol polyphosphate 5-phosphatase from a blood-feeding insect: allosteric activation by soluble phosphoinositides and phosphatidylserine
Biochemistry
45
5450-5457
2006
Rhodnius prolixus
Vaillancourt, M.; Levasseur, S.; Tremblay, M.L.; Marois, L.; Rollet-Labelle, E.; Naccache, P.H.
The Src homology 2-containing inositol 5-phosphatase 1 (SHIP1) is involved in CD32a signaling in human neutrophils
Cell. Signal.
18
2022-2032
2006
Homo sapiens
Vandeput, F.; Backers, K.; Villeret, V.; Pesesse, X.; Erneux, C.
The influence of anionic lipids on SHIP2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase activity
Cell. Signal.
18
2193-2199
2006
Homo sapiens
Zhang, J.; Liu, Z.; Rasschaert, J.; Blero, D.; Deneubourg, L.; Schurmans, S.; Erneux, C.; Pesesse, X.
SHIP2 controls PtdIns(3,4,5)P(3) levels and PKB activity in response to oxidative stress
Cell. Signal.
19
2194-2200
2007
Mus musculus
Grempler, R.; Zibrova, D.; Schoelch, C.; van Marle, A.; Rippmann, J.F.; Redemann, N.
Normalization of prandial blood glucose and improvement of glucose tolerance by liver-specific inhibition of SH2 domain containing inositol phosphatase 2 (SHIP2) in diabetic KKAy mice: SHIP2 inhibition causes insulin-mimetic effects on glycogen metabolism
Diabetes
56
2235-2241
2007
Mus musculus
Bertelli, D.F.; Araujo, E.P.; Cesquini, M.; Stoppa, G.R.; Gasparotto-Contessotto, M.; Toyama, M.H.; Felix, J.V.; Carvalheira, J.B.; Michelini, L.C.; Chiavegatto, S.; Boschero, A.C.; Saad, M.J.; Lopes-Cendes, I.; Velloso, L.A.
Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits inositide trisphosphate accumulation in hypothalamus and regulates food intake and body weight
Endocrinology
147
5385-5399
2006
Rattus norvegicus
Kimata, T.; Nagaki, M.; Ogiso, T.; Naiki, T.; Kato, T.; Moriwaki, H.
Actin organization and hepatocyte differentiation are regulated by extracellular matrix via PI-4,5-bisphosphate in the rat
Hepatology
44
140-151
2006
Rattus norvegicus
van Zeijl, L.; Ponsioen, B.; Giepmans, B.N.; Ariaens, A.; Postma, F.R.; Varnai, P.; Balla, T.; Divecha, N.; Jalink, K.; Moolenaar, W.H.
Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate
J. Cell Biol.
177
881-891
2007
Homo sapiens
Williams, C.; Choudhury, R.; McKenzie, E.; Lowe, M.
Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway
J. Cell Sci.
120
3941-3951
2007
Homo sapiens (P32019)
Onnockx, S.; De Schutter, J.; Blockmans, M.; Xie, J.; Jacobs, C.; Vanderwinden, J.M.; Erneux, C.; Pirson, I.
The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners
J. Cell. Physiol.
214
260-272
2008
Homo sapiens
Leung, W.H.; Bolland, S.
The inositol 5-phosphatase SHIP-2 negatively regulates IgE-induced mast cell degranulation and cytokine production
J. Immunol.
179
95-102
2007
Mus musculus
Nishio, M.; Watanabe, K.; Sasaki, J.; Taya, C.; Takasuga, S.; Iizuka, R.; Balla, T.; Yamazaki, M.; Watanabe, H.; Itoh, R.; Kuroda, S.; Horie, Y.; Foerster, I.; Mak, T.W.; Yonekawa, H.; Penninger, J.M.; Kanaho, Y.; Suzuki, A.; Sasaki, T.
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
Nat. Cell Biol.
9
36-44
2007
Mus musculus
Mani, M.; Lee, S.Y.; Lucast, L.; Cremona, O.; Di Paolo, G.; De Camilli, P.; Ryan, T.A.
The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals
Neuron
56
1004-1018
2007
Homo sapiens
Chen, X.; Lin, W.H.; Wang, Y.; Luan, S.; Xue, H.W.
An inositol polyphosphate 5-phosphatase functions in PHOTOTROPIN1 signaling in Arabidopis by altering cytosolic Ca2+
Plant Cell
20
353-366
2008
Arabidopsis thaliana (Q9SYK4), Arabidopsis thaliana
Perera, R.M.; Zoncu, R.; Lucast, L.; De Camilli, P.; Toomre, D.
Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages
Proc. Natl. Acad. Sci. USA
103
19332-19337
2006
Homo sapiens
Loovers, H.M.; Kortholt, A.; de Groote, H.; Whitty, L.; Nussbaum, R.L.; van Haastert, P.J.
Regulation of phagocytosis in Dictyostelium by the inositol 5-phosphatase OCRL homolog Dd5P4
Traffic
8
618-628
2007
Dictyostelium discoideum
Hung, C.S.; Lin, Y.L.; Wu, C.I.; Huang, C.J.; Ting, L.P.
Suppression of hepatitis B viral gene expression by phosphoinositide 5-phosphatase SKIP
Cell. Microbiol.
11
37-50
2009
Homo sapiens
Weber, S.S.; Ragaz, C.; Hilbi, H.
The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE
Cell. Microbiol.
11
442-460
2008
Dictyostelium discoideum, Homo sapiens, Mus musculus
Xie, J.; Onnockx, S.; Vandenbroere, I.; Degraef, C.; Erneux, C.; Pirson, I.
The docking properties of SHIP2 influence both JIP1 tyrosine phosphorylation and JNK activity
Cell. Signal.
20
1432-1441
2008
Homo sapiens
Mills, S.J.; Vandeput, F.; Trusselle, M.N.; Safrany, S.T.; Erneux, C.; Potter, B.V.
Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5-trisphosphate 5-phosphatase and interaction with the pH domain of protein kinase Balpha
ChemBioChem
9
1757-1766
2008
Homo sapiens
Xie, J.; Vandenbroere, I.; Pirson, I.
SHIP2 associates with intersectin and recruits it to the plasma membrane in response to EGF
FEBS Lett.
582
3011-3017
2008
Homo sapiens
Thyagarajan, B.; Lukacs, V.; Rohacs, T.
Hydrolysis of phosphatidylinositol 4,5-bisphosphate mediates calcium-induced inactivation of TRPV6 channels
J. Biol. Chem.
283
14980-14987
2008
Homo sapiens
Choudhury, R.; Noakes, C.J.; McKenzie, E.; Kox, C.; Lowe, M.
Differential clathrin binding and subcellular localization of OCRL1 splice isoforms
J. Biol. Chem.
284
9965-9973
2009
Homo sapiens (Q01968)
Artemenko, Y.; Gagnon, A.; Sorisky, A.
Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes
J. Cell. Physiol.
218
228-236
2009
Homo sapiens
Zhang, Y.; Wavreille, A.S.; Kunys, A.R.; Pei, D.
The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics
Biochemistry
48
11075-11083
2009
Homo sapiens
Cui, S.; Guerriero, C.; Szalinski, C.; Kinlough, C.; Hughey, R.; Weisz, O.
OCRL1 function in renal epithelial membrane traffic
Am. J. Physiol. Renal Physiol.
298
F335-F345
2010
Canis lupus familiaris, Homo sapiens
Bakowski, M.A.; Braun, V.; Lam, G.Y.; Yeung, T.; Heo, W.D.; Meyer, T.; Finlay, B.B.; Grinstein, S.; Brumell, J.H.
The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole
Cell Host Microbe
7
453-462
2010
Salmonella enterica
Deng, X.; Feng, C.; Wang, E.H.; Zhu, Y.Q.; Cui, C.; Zong, Z.H.; Li, G.S.; Liu, C.; Meng, J.; Yu, B.Z.
Influence of proline-rich inositol polyphosphate 5-phosphatase, on early development of fertilized mouse eggs, via inhibition of phosphorylation of Akt
Cell Prolif.
44
156-165
2011
Mus musculus, Mus musculus Kunming
Ben El Kadhi, K.; Roubinet, C.; Solinet, S.; Emery, G.; Carreno, S.
The inositol 5-phosphatase dOCRL controls PI(4,5)P2 homeostasis and is necessary for cytokinesis
Curr. Biol.
21
1074-1079
2011
Drosophila melanogaster
Nakatsu, F.; Perera, R.; Lucast, L.; Zoncu, R.; Domin, J.; Gertler, F.; Toomre, D.; De Camilli, P.
The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics
J. Cell Biol.
190
307-315
2010
Mus musculus
Lindner, M.; Leitner, M.G.; Halaszovich, C.R.; Hammond, G.R.; Oliver, D.
Probing the regulation of TASK potassium channels by PI(4,5)P2 with switchable phosphoinositide phosphatases
J. Physiol.
589
3149-3162
2011
Homo sapiens (Q9NRR6)
Fabian, L.; Wei, H.; Rollins, J.; Noguchi, T.; Blankenship, J.; Bellamkonda, K.; Polevoy, G.; Gervais, L.; Guichet, A.; Fuller, M.; Brill, J.
Phosphatidylinositol 4,5-bisphosphate directs spermatid cell polarity and exocyst localization in Drosophila
Mol. Biol. Cell
21
1546-1555
2010
Drosophila melanogaster
Soeda, Y.; Tsuneki, H.; Muranaka, H.; Mori, N.; Hosoh, S.; Ichihara, Y.; Kagawa, S.; Wang, X.; Toyooka, N.; Takamura, Y.; Uwano, T.; Nishijo, H.; Wada, T.; Sasaoka, T.
The inositol phosphatase SHIP2 negatively regulates insulin/IGF-I actions implicated in neuroprotection and memory function in mouse brain
Mol. Endocrinol.
24
1965-1977
2010
Mus musculus (Q6P549), Mus musculus, Mus musculus C57/BL6J (Q6P549)
Dambournet, D.; MacHicoane, M.; Chesneau, L.; Sachse, M.; Rocancourt, M.; El Marjou, A.; Formstecher, E.; Salomon, R.; Goud, B.; Echard, A.
Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis
Nat. Cell Biol.
13
981-988
2011
Homo sapiens
Suh, B.; Leal, K.; Hille, B.
Modulation of high-voltage activated Ca2+ channels by membrane phosphatidylinositol 4,5-bisphosphate
Neuron
67
224-238
2010
Danio rerio
Kaye, Y.; Golani, Y.; Singer, Y.; Leshem, Y.; Cohen, G.; Ercetin, M.; Gillaspy, G.; Levine, A.
Inositol polyphosphate 5-phosphatase7 regulates the production of reactive oxygen species and salt tolerance in Arabidopsis
Plant Physiol.
157
229-241
2011
Arabidopsis thaliana
Vollmer, A.H.; Youssef, N.N.; Dewald, D.B.
Unique cell wall abnormalities in the putative phosphoinositide phosphatase mutant AtSAC9
Planta
234
993-1005
2011
Arabidopsis thaliana, Arabidopsis thaliana CS1092
Broberg, C.; Zhang, L.; Gonzalez, H.; Laskowski-Arce, M.; Orth, K.
A Vibrio effector protein is an inositol phosphatase and disrupts host cell membrane integrity
Science
329
1660-1662
2010
Vibrio parahaemolyticus
Miyazawa, K.
Phosphoinositide 5-phosphatases: How do they affect tumourigenesis?
J. Biochem.
153
1-3
2013
Homo sapiens (Q9NRR6)
Ijuin, T.; Takenawa, T.
Role of phosphatidylinositol 3,4,5-trisphosphate (PIP3) 5-phosphatase skeletal muscle- and kidney-enriched inositol polyphosphate phosphatase (SKIP) in myoblast differentiation
J. Biol. Chem.
287
31330-31341
2012
Homo sapiens, Mus musculus
Ye, Y.; Jin, L.; Wilmott, J.S.; Hu, W.L.; Yosufi, B.; Thorne, R.F.; Liu, T.; Rizos, H.; Yan, X.G.; Dong, L.; Tay, K.H.; Tseng, H.Y.; Guo, S.T.; de Bock, C.E.; Jiang, C.C.; Wang, C.Y.; Wu, M.; Zhang, L.J.; Hersey, P.; Scolyer, R.A.; Zhang, X.D.
PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma
Nat. Commun.
4
1508
2013
Homo sapiens
Braun, W.; Schein, C.
Membrane interaction and functional plasticity of inositol polyphosphate 5-phosphatases
Structure
22
664-666
2014
Homo sapiens, Homo sapiens (P32019)
Tresaugues, L.; Silvander, C.; Flodin, S.; Welin, M.; Nyman, T.; Graeslund, S.; Hammarstroem, M.; Berglund, H.; Nordlund, P.
Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases
Structure
22
744-755
2014
Homo sapiens (P32019), Homo sapiens (Q01968), Homo sapiens
Kuehbacher, A.; Dambournet, D.; Echard, A.; Cossart, P.; Pizarro-Cerda, J.
Phosphatidylinositol 5-phosphatase oculocerebrorenal syndrome of Lowe protein (OCRL) controls actin dynamics during early steps of Listeria monocytogenes infection
J. Biol. Chem.
287
13128-13136
2012
Listeria monocytogenes
Ijuin, T.; Takenawa, T.
Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP)
J. Biol. Chem.
287
6991-6999
2012
Mus musculus
Mondal, S.; Subramanian, K.K.; Sakai, J.; Bajrami, B.; Luo, H.R.
Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion
Mol. Biol. Cell
23
1219-1230
2012
Mus musculus
Kato, K.; Yazawa, T.; Taki, K.; Mori, K.; Wang, S.; Nishioka, T.; Hamaguchi, T.; Itoh, T.; Takenawa, T.; Kataoka, C.; Matsuura, Y.; Amano, M.; Murohara, T.; Kaibuchi, K.
The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration
Mol. Biol. Cell
23
2593-2604
2012
Homo sapiens
Mills, S.J.; Silvander, C.; Cozier, G.; Tresaugues, L.; Nordlund, P.; Potter, B.V.
Crystal Structures of type-II inositol polyphosphate 5-phosphatase INPP5B with synthetic inositol polyphosphate surrogates reveal new mechanistic insights for the inositol 5-phosphatase family
Biochemistry
55
1384-1397
2016
Homo sapiens (P32019)
Kume, A.; Kawase, K.; Komenoi, S.; Usuki, T.; Takeshita, E.; Sakai, H.; Sakane, F.
The pleckstrin homology domain of diacylglycerol kinase eta strongly and selectively binds to phosphatidylinositol 4,5-bisphosphate
J. Biol. Chem.
291
8150-8161
2016
Homo sapiens
Chen, D.; Yang, C.; Liu, S.; Hang, W.; Wang, X.; Chen, J.; Shi, A.
SAC-1 ensures epithelial endocytic recycling by restricting ARF-6 activity
J. Cell Biol.
217
2121-2139
2018
Caenorhabditis elegans
Plotnikova, O.; Seo, S.; Cottle, D.; Conduit, S.; Hakim, S.; Dyson, J.; Mitchell, C.; Smyth, I.
INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability
J. Cell Sci.
128
364-372
2015
Mus musculus (Q9JII1)
Cestari, I.; McLeland-Wieser, H.; Stuart, K.
Nuclear phosphatidylinositol 5-phosphatase is essential for allelic exclusion of variant surface glycoprotein genes in trypanosomes
Mol. Cell. Biol.
39
e00395-18
2019
Trypanosoma brucei
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