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Alzheimer Disease
Alteration of myo-inositol monophosphatase in Alzheimer's disease brains.
Arthritis
Immune myopathies with perimysial pathology: Clinical and laboratory features.
Breast Neoplasms
A novel oncogenic role of inositol phosphatase SHIP2 in ER-negative breast cancer stem cells: involvement of JNK/vimentin activation.
Breast Neoplasms
Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases.
Carcinoma
A novel function of IMPA2, plays a tumor-promoting role in cervical cancer.
Carcinoma
Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function.
Carcinoma
Decreased cyclic inositol phosphohydrolase activity in hamster renal tumors and human renal cell carcinomas.
Carcinoma
IMPA2 Downregulation Enhances mTORC1 Activity and Restrains Autophagy Initiation in Metastatic Clear Cell Renal Cell Carcinoma.
Carcinoma in Situ
A novel function of IMPA2, plays a tumor-promoting role in cervical cancer.
Carcinoma, Renal Cell
Decreased cyclic inositol phosphohydrolase activity in hamster renal tumors and human renal cell carcinomas.
Carcinoma, Renal Cell
IMPA2 Downregulation Enhances mTORC1 Activity and Restrains Autophagy Initiation in Metastatic Clear Cell Renal Cell Carcinoma.
Cardiomegaly
Inpp5f Is a Polyphosphoinositide Phosphatase That Regulates Cardiac Hypertrophic Responsiveness.
Cardiomyopathies
[Evolution and thromboembolic complications of the idiopathic peripartal cardiomyopathy at Dakar University Hospital: forward-looking study about 33 cases].
Cardiovascular Diseases
[Treatment of erectile dysfunction in patients with ischemic heart disease and angina of effort]
Chronic Periodontitis
Upregulation of immunoregulatory Src homology 2 molecule containing inositol phosphatase and mononuclear cell hyporesponsiveness in oral mucosa during chronic periodontitis.
Dementia
Inositol monophosphatase activity in normal, Down syndrome and dementia of the Alzheimer type CSF.
Dementia, Multi-Infarct
Inositol monophosphatase activity in normal, Down syndrome and dementia of the Alzheimer type CSF.
Dermatomyositis
Immune myopathies with perimysial pathology: Clinical and laboratory features.
Diabetes Mellitus, Type 2
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
Diabetes, Gestational
Placental Inositol Reduced in Gestational Diabetes as Glucose Alters Inositol Transporters and IMPA1 Enzyme Expression.
Diabetic Cardiomyopathies
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
Down Syndrome
Inositol monophosphatase activity in normal, Down syndrome and dementia of the Alzheimer type CSF.
Drug Resistant Epilepsy
Inositol phosphatase INPP4A inhibits the apoptosis of in vitro neurons with characteristic of intractable epilepsy by reducing intracellular Ca2+ concentration.
Epilepsy
Impaired neuronal activity and differential gene expression in STXBP1 encephalopathy patient iPSC-derived GABAergic neurons.
Erectile Dysfunction
[An open non-comparative study of impase for treating erectile dysfunction]
Erectile Dysfunction
[Correction of erectile dysfunction in patients with chronic abacterial prostatitis].
Erectile Dysfunction
[Impase in the treatment of erectile dysfunction]
Erectile Dysfunction
[Treatment of erectile dysfunction in patients with ischemic heart disease and angina of effort]
Erectile Dysfunction
[Use of impase in the therapy of erectile dysfunction]
Erectile Dysfunction
[Viagra, cialis, impase--which of them, to whom, when and how?]
Galactosemias
Expression of human inositol monophosphatase suppresses galactose toxicity in Saccharomyces cerevisiae: possible implications in galactosemia.
Glioblastoma
Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.
Glioma
Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.
Glioma
Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3.
Heart Defects, Congenital
Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations.
Hepatitis, Alcoholic
Antioxidant and hepatoprotective effects of intracellular mycelium polysaccharides from Pleurotus geesteranus against alcoholic liver diseases.
Huntington Disease
Potential protective effects of autophagy activated in MPP+ treated astrocytes.
Hyperglycemia
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
Hyperlipidemias
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
Hypertension, Pulmonary
Inositol monophosphatase 1 as a novel interacting partner of RAGE in pulmonary hypertension.
Infections
Effects of the deletion and over-expression of Fusarium graminearum gene FgHal2 on host response to mycovirus Fusarium graminearum virus 1.
Infections
Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.
Infections
The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo.
inositol-phosphate phosphatase deficiency
Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis.
Intellectual Disability
A homozygous loss-of-function mutation in inositol monophosphatase 1 (IMPA1) causes severe intellectual disability.
Intellectual Disability
Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis.
Intellectual Disability
Loss-of-function mutation in inositol monophosphatase 1 (IMPA1) results in abnormal synchrony in resting-state EEG.
Ischemic Stroke
IMPA2 polymorphisms and risk of ischemic stroke in a northwest Han Chinese population.
Leukemia, Lymphocytic, Chronic, B-Cell
Gene expression of INPP5F as an independent prognostic marker in fludarabine-based therapy of chronic lymphocytic leukemia.
Lung Diseases, Interstitial
Immune myopathies with perimysial pathology: Clinical and laboratory features.
Lung Neoplasms
Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Malnutrition
Effects of neonatal undernutrition and subsequent nutritional rehabilitation or administration of thyroxine and hydrocortisone on the inositol phosphatase activities in rat intestine.
Malnutrition
Effects of postweaning protein malnutrition on intestinal inositol phosphatase activities in normally weaned and neonatally undernourished rats.
Mania
Inositol deficiency diet and lithium effects.
Melanoma
Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases.
Muscular Diseases
Immune myopathies with perimysial pathology: Clinical and laboratory features.
Muscular Dystrophies
Fine mapping of the muscular dystrophy (AM) gene on chicken chromosome 2q.
Neoplasm Metastasis
A novel function of IMPA2, plays a tumor-promoting role in cervical cancer.
Neoplasm Metastasis
Dysregulation of the miR-25-IMPA2 axis promotes metastatic progression in clear cell renal cell carcinoma.
Neoplasms
A novel function of IMPA2, plays a tumor-promoting role in cervical cancer.
Neoplasms
Decreased cyclic inositol phosphohydrolase activity in hamster renal tumors and human renal cell carcinomas.
Neoplasms
Dysregulation of the miR-25-IMPA2 axis promotes metastatic progression in clear cell renal cell carcinoma.
Neoplasms
Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Neoplasms
Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN.
Neoplasms
Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity.
Neoplasms
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
Neoplasms
Predicting which children are at risk for ependymoma relapse.
Neoplasms
Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases.
Neuralgia
Effect of HDAC2/Inpp5f on neuropathic pain and cognitive function through regulating PI3K/Akt/GSK-3? signal pathway in rats with neuropathic pain.
Neuralgia
Pregabalin on Hdac2 and Inpp5f levels in rats with CCI-induced neuropathic pain.
Neuroblastoma
Beryllium competitively inhibits brain myo-inositol monophosphatase, but unlike lithium does not enhance agonist-induced inositol phosphate accumulation.
Neurodegenerative Diseases
Potential protective effects of autophagy activated in MPP+ treated astrocytes.
Obesity
An investigation of obesity susceptibility genes in Northern Han Chinese by targeted resequencing.
Oculocerebrorenal Syndrome
IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis.
Parkinson Disease
Association of four new candidate genetic variants with Parkinson's disease in a Han Chinese population.
Raynaud Disease
Immune myopathies with perimysial pathology: Clinical and laboratory features.
Seizures
Effects of the putative lithium mimetic ebselen on pilocarpine-induced neural activity.
Seizures
Hippocampal transcriptional and neurogenic changes evoked by combination yohimbine and imipramine treatment.
Seizures
IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity.
Seizures
Inositol-deficient food augments a behavioral effect of long-term lithium treatment mediated by inositol monophosphatase inhibition: an animal model with relevance for bipolar disorder.
Seizures
Intracerebroventricular antisense to inositol monophosphatase-1 reduces enzyme activity but does not affect Li-sensitive behavior.
Seizures
Modulation of phosphatidylinositol turnover on central nicotinic receptors.
Seizures
The inositol monophosphatase inhibitor L-690,330 affects pilocarpine-behavior and the forced swim test.
Seizures
Ziskind-Somerfeld Research Award 1993. Biochemical, behavioral, and clinical studies of the role of inositol in lithium treatment and depression.
Seizures, Febrile
Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures.
Seizures, Febrile
Genetic variants in the IMPA2 gene do not confer increased risk of febrile seizures in Caucasian patients.
Seizures, Febrile
Linkage and association of febrile seizures to the IMPA2 gene on human chromosome 18.
Seizures, Febrile
Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1.
Spinal Cord Injuries
Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury.
Spinocerebellar Ataxias
Bergmann glial S100B activates myo-inositol monophosphatase 1 and Co-localizes to purkinje cell vacuoles in SCA1 transgenic mice.
Thrombosis
[Evolution and thromboembolic complications of the idiopathic peripartal cardiomyopathy at Dakar University Hospital: forward-looking study about 33 cases].
Tuberculosis
Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg2+
Tuberculosis
Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis.
Tuberculosis
Purification and biochemical characterization of Mycobacterium tuberculosis SuhB, an inositol monophosphatase involved in inositol biosynthesis.
Uterine Cervical Neoplasms
A novel function of IMPA2, plays a tumor-promoting role in cervical cancer.
Virus Diseases
Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.
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3.1.3.25 inositol-phosphate phosphatase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
