Information on EC 3.1.3.19 - glycerol-2-phosphatase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.1.3.19
-
RECOMMENDED NAME
GeneOntology No.
glycerol-2-phosphatase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
glycerol 2-phosphate + H2O = glycerol + phosphate
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
SYSTEMATIC NAME
IUBMB Comments
glycerol-2-phosphate phosphohydrolase
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CAS REGISTRY NUMBER
COMMENTARY hide
9027-39-8
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
with Thanatephorus cucumeris
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-
Manually annotated by BRENDA team
Dawsonia spp.
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Fissidens sp.
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
barley
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-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
var. austriaca
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-
Manually annotated by BRENDA team
Pisum sativum var. Alaska
-
-
-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
Polytrichum spp.
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-
-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
wheat
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-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
mung bean
-
-
Manually annotated by BRENDA team
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-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-phosphoglycerate + H2O
?
show the reaction diagram
2-phosphoglycerol + H2O
glycerol + phosphate
show the reaction diagram
-
-
-
-
?
3-phosphoglycerate + H2O
glyceric acid + phosphate
show the reaction diagram
-
-
-
-
?
ATP + H2O
?
show the reaction diagram
glycerol 2-phosphate + H2O
glycerol + phosphate
show the reaction diagram
-
-
-
-
-
glycerophosphate + H2O
?
show the reaction diagram
-
-
-
-
?
UTP + H2O
?
show the reaction diagram
additional information
?
-
-
the presence of lysosomal enzymes like trimetaphosphatase observed in mononuclear phagocytes in the circulating blood indicating that these cells are able to participate in the phagocytic process gathering many phagocytic cells and forming multinucleated giant cells, possibly having a role in the blood clearance process
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-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
glycerol 2-phosphate + H2O
glycerol + phosphate
show the reaction diagram
-
-
-
-
-
additional information
?
-
-
the presence of lysosomal enzymes like trimetaphosphatase observed in mononuclear phagocytes in the circulating blood indicating that these cells are able to participate in the phagocytic process gathering many phagocytic cells and forming multinucleated giant cells, possibly having a role in the blood clearance process
-
-
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Fe3+
-
-
Mn2+
-
slight stimulating effect
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
acrolein
actinomycin D
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cycloheximide
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Fe2+
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formalin
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Glutaraldehyde
Hydroxyurea
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inhibitor of DNA synthesis
Inositol
Mn2+
-
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
aspartic acid
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activation
cysteine
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activation
glutathione
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activation
histidine
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activation
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0062
2-Phosphoglycerol
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-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
21 - 200
additional information
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
37
-
assay at
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
differentiating
Manually annotated by BRENDA team
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-
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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; within
Manually annotated by BRENDA team
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; phagolysosome, inside, not surrounding
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Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partial, 80fold
-
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
yeast strain ATCC9080, deficient in inositol synthesis