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Information on EC 3.1.3.13 - bisphosphoglycerate phosphatase and Organism(s) Homo sapiens and UniProt Accession P07738

for references in articles please use BRENDA:EC3.1.3.13
deleted, activity due to EC 5.4.2.11, phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.13 bisphosphoglycerate phosphatase
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
137.5
2,3-bisphospho-D-glycerate
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at pH 7.1 and 30°C
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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the trifunctional enzyme regulates the level of 2,3-bisphosphoglycerate in red blood cells, the 2,3-bisphosphoglycerate phosphatase activity is responsible for rapid decline of 2,3-bisphosphoglycerate from storage in erythrocytes following fall of pH to limit the release of hemoglobin to blood
additional information
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the erythrocytic enzyme is trifunctional exhibiting 2,3-diphosphoglycerate phosphatase, synthase, and mutase activities, overview