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Information on EC 3.1.26.4 - ribonuclease H and Organism(s) Thermovibrio ammonificans and UniProt Accession E8T217

for references in articles please use BRENDA:EC3.1.26.4
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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.26 Endoribonucleases producing 5'-phosphomonoesters
                3.1.26.4 ribonuclease H
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This record set is specific for:
Thermovibrio ammonificans
UNIPROT: E8T217 not found.
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The taxonomic range for the selected organisms is: Thermovibrio ammonificans
The enzyme appears in selected viruses and cellular organisms
Reaction Schemes
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Endonucleolytic cleavage to a 5'-phosphomonoester
Synonyms
reverse transcriptase, ribonuclease h, rnase h2, rnase hii, rnaseh2a, rnaseh1, ribonuclease hi, ribonuclease h2, rnase hiii, ribonuclease h1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
endoribonuclease H
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hybrid nuclease
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hybrid ribonuclease
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-
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hybridase
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hybridase (ribonuclease H)
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nuclease, hybrid ribo-
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nuclease, ribo-, H
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P32
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ribonuclease H
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RNA*DNA hybrid ribonucleotidohydrolase
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RNase H
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RNase H1
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RNase HI
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RNase HII
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-
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RNase HIII
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of phosphoric ester
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CAS REGISTRY NUMBER
COMMENTARY hide
9050-76-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
RNA-DNA hybrid + H2O
?
show the reaction diagram
RNases H3 recognizes the 2'-OH groups of the RNA strand and detects the DNA strand by binding a phosphate group and inducing B-form conformation
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-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
RNA-DNA hybrid + H2O
?
show the reaction diagram
RNases H3 recognizes the 2'-OH groups of the RNA strand and detects the DNA strand by binding a phosphate group and inducing B-form conformation
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Figiel, M.; Nowotny, M.
Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition
Nucleic Acids Res.
42
9285-9294
2014
Thermovibrio ammonificans (E8T217), Thermovibrio ammonificans DSM 15698 (E8T217)
Manually annotated by BRENDA team