Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Abortion, Spontaneous
Research advances of Dicer in regulating reproductive function.
Abortion, Spontaneous
The effects of DICER1 and DROSHA polymorphisms on susceptibility to recurrent spontaneous abortion.
Acquired Immunodeficiency Syndrome
Characterization of the reactivity determinants of a novel hairpin substrate of yeast RNase III.
Adenocarcinoma
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Adenocarcinoma
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Adenocarcinoma
DICER1 expression and outcomes in endometrioid endometrial adenocarcinoma.
Adenocarcinoma
DICER1 mutations in a patient with an ovarian Sertoli-Leydig tumor, well-differentiated fetal adenocarcinoma of the lung, and familial multinodular goiter.
Adenocarcinoma
DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.
Adenocarcinoma
Germline and Somatic DICER1 Mutations in a Well-Differentiated Fetal Adenocarcinoma of the Lung.
Adenocarcinoma
Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances.
Adenocarcinoma
miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma.
Adenocarcinoma
Overexpression of Dicer in precursor lesions of lung adenocarcinoma.
Adenocarcinoma
Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma.
Adenocarcinoma
Serum Exosomal Dicer Is a Useful Biomarker for Early Detection of Differentiated Gastric Adenocarcinoma.
Adenocarcinoma
The prevalence of germline DICER1 pathogenic variation in cancer populations.
Adenocarcinoma
The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer.
Adenocarcinoma
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma.
Adenocarcinoma
[A negative correlation between Drosha expression and gastric adenocarcinoma malignancy and invasion].
Adenocarcinoma of Lung
Overexpression of Dicer in precursor lesions of lung adenocarcinoma.
Adenocarcinoma, Follicular
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma.
Adenocarcinoma, Follicular
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours.
Adenocarcinoma, Follicular
Macrofollicular variant follicular thyroid tumors are DICER1 mutated and exhibit distinct histological features.
Adenocarcinoma, Follicular
Macrofollicular Variant of Follicular Thyroid Carcinoma (MV-FTC) with a Somatic DICER1 Gene Mutation: Case Report and Review of the Literature.
Adenocarcinoma, Follicular
Predominant DICER1 Pathogenic Variants in Pediatric Follicular Thyroid Carcinomas.
Adenocarcinoma, Mucinous
An Unusual Enteric Yolk Sac Tumor: First Report of an Ovarian Germ Cell Tumor Associated With a Germline Pathogenic Variant in DICER1.
Adenocarcinoma, Mucinous
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Adenoma
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma.
Adenoma
Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma.
Adenoma
Predominant DICER1 Pathogenic Variants in Pediatric Follicular Thyroid Carcinomas.
Adenomatous Polyposis Coli
Familial non-medullary thyroid cancer: unraveling the genetic maze.
Adenomatous Polyposis Coli
Familial non-medullary thyroid carcinoma: clinico-pathological features, current knowledge and novelty regarding genetic risk factors.
Adenosarcoma
DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation.
Adenosarcoma
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Adenosarcoma
Endometrial adenosarcoma in the setting of a germline DICER1 mutation: A case report.
Adenosarcoma
Endometrial Stem/Progenitor cell (ES/PC) Marker Expression Profile in Adenosarcoma and Endometrial Stromal Sarcoma.
Adenosarcoma
Significantly greater prevalence of DICER1 alterations in uterine embryonal rhabdomyosarcoma compared to adenosarcoma.
Adrenocortical Carcinoma
Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma.
Agenesis of Corpus Callosum
Biallelic PMS2 Mutation and Heterozygous DICER1 Mutation Presenting as Constitutional Mismatch Repair Deficiency With Corpus Callosum Agenesis: Case Report and Review of Literature.
Alphavirus Infections
Production of virus-derived ping-pong-dependent piRNA-like small RNAs in the mosquito soma.
Alzheimer Disease
Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via A?42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2.
Alzheimer Disease
Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression.
Alzheimer Disease
Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and A?1-42 in female 3xTg-AD mice.
Alzheimer Disease
p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease.
Anaphylaxis
Global microRNA expression is essential for murine mast cell development in vivo.
Anemia
Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice.
Arthritis
Reduced DICER1 expression bestows rheumatoid arthritis synoviocytes proinflammatory properties and resistance to apoptotic stimuli.
Arthritis
Transcriptome study of differential expression in schizophrenia.
Arthritis, Rheumatoid
DICER and DROSHA gene expression in peripheral mononuclear blood cells from rheumatoid arthritis patients under methotrexate therapy.
Arthritis, Rheumatoid
DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.
Arthritis, Rheumatoid
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Arthritis, Rheumatoid
Expression of Dicer in rheumatoid arthritis is associated with disease activity and balances the production of TNF??.
Arthritis, Rheumatoid
Reduced DICER1 expression bestows rheumatoid arthritis synoviocytes proinflammatory properties and resistance to apoptotic stimuli.
Asthma
CEACAM3 decreases asthma exacerbations and modulates respiratory syncytial virus latent infection in children.
Asthma
Eosinophil cationic protein (ECP) polymorphisms and association with asthma, s-ECP levels and related phenotypes.
Asthma
Outcome of two pairs of monozygotic twins with pleuropulmonary blastoma: case report.
Astrocytoma
Markers of mRNA stabilization and degradation, and RNAi within astrocytoma GW bodies.
Ataxia
Cerebellar neurodegeneration in the absence of microRNAs.
Ataxia
Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration.
Ataxia
The deletion of dicer in mature myelinating glial cells causes progressive axonal degeneration but not overt demyelination in adult mice.
Ataxia Telangiectasia
Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB.
Atherosclerosis
Correction to: Dicer in Macrophages Prevents Atherosclerosis by Promoting Mitochondrial Oxidative Metabolism.
Atherosclerosis
Corrigendum: Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4.
Atherosclerosis
Dicer in Macrophages Prevents Atherosclerosis by Promoting Mitochondrial Oxidative Metabolism.
Atherosclerosis
Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4.
Autoimmune Diseases
Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease.
Autoimmune Diseases
Evidence for microRNA-mediated regulation in rheumatic diseases.
Avian Leukosis
Development of a new duplex real-time polymerase chain reaction assay for detection of dicer in G. gallus.
Azoospermia
Association of rs1057035polymorphism in microRNA biogenesis pathway gene (DICER1) with azoospermia among Iranian population.
Azoospermia
Research advances of Dicer in regulating reproductive function.
Azoospermia
The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis.
Azoospermia
[Association of polymorphisms of miRNA biogenesis related genes DICER and DROSHA with azoospermia].
Bacterial Infections
Dual-action of thermoresponsive gels containing DsiRNA-loaded gold nanoparticles for diabetic wound therapy: Characterization, in vitro safety and healing efficacy.
Basal Cell Nevus Syndrome
Gynecological lesions in hereditary cancer predisposition syndromes.
Beckwith-Wiedemann Syndrome
Germline predisposition to genitourinary rhabdomyosarcoma.
Bicuspid Aortic Valve Disease
Genetic polymorphisms of miRNA machinery genes in bicuspid aortic valve and associated aortopathy.
Blindness
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
Blindness
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation.
Blindness
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.
Blindness
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Blindness
ERK1/2 activation is a therapeutic target in age-related macular degeneration.
Bloom Syndrome
Contribution of domain structure to the RNA 3' end processing and degradation functions of the nuclear exosome subunit Rrp6p.
Bloom Syndrome
Recent advances in Wilms tumor predisposition.
Bone Marrow Failure Disorders
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.
Bone Resorption
Impaired micro-RNA pathways diminish osteoclast differentiation and function.
Bone Resorption
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption.
Brain Injuries, Traumatic
Increased miR-21-3p in injured brain microvascular endothelial cells following traumatic brain injury aggravates blood-brain barrier damage by promoting cellular apoptosis and inflammation through targeting MAT2B.
Brain Neoplasms
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Breast Neoplasms
A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
Breast Neoplasms
A dual role of miR-22 modulated by RelA/p65 in resensitizing fulvestrant-resistant breast cancer cells to fulvestrant by targeting FOXP1 and HDAC4 and constitutive acetylation of p53 at Lys382.
Breast Neoplasms
Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.
Breast Neoplasms
Amplification of Hsa-miR-191/425 Locus Promotes Breast Cancer Proliferation and Metastasis by Targeting DICER1.
Breast Neoplasms
Cellular Delivery of siRNAs Using Bolaamphiphiles.
Breast Neoplasms
Complexity in Regulation of microRNA Machinery Components in Invasive Breast Carcinoma.
Breast Neoplasms
Complexity in the regulation of Dicer expression: Dicer variant proteins are differentially expressed in epithelial and mesenchymal breast cancer cells and decreased during EMT.
Breast Neoplasms
Concordant and Discordant Regulation of Target Genes by miR-31 and Its Isoforms.
Breast Neoplasms
Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer.
Breast Neoplasms
Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL.
Breast Neoplasms
Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison.
Breast Neoplasms
Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells.
Breast Neoplasms
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer.
Breast Neoplasms
Dysregulated Expression of Dicer and Drosha in Breast Cancer.
Breast Neoplasms
Dysregulated expression of Dicer in invasive ductal breast carcinoma.
Breast Neoplasms
Evaluation of genetic variants in microRNA biosynthesis genes and risk of breast cancer in Chinese women.
Breast Neoplasms
Expression of Dicer and Drosha in triple-negative breast cancer.
Breast Neoplasms
Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis.
Breast Neoplasms
Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.
Breast Neoplasms
Germline mutations of DICER1 in Chinese women with BRCA1/BRCA2-negative familial breast cancer.
Breast Neoplasms
Hippo/MST blocks breast cancer by downregulating WBP2 oncogene expression via miRNA processor Dicer.
Breast Neoplasms
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.
Breast Neoplasms
Hypoxia represses microRNA biogenesis proteins in breast cancer cells.
Breast Neoplasms
Identification and characterization of Dicer1e, a Dicer1 protein variant, in oral cancer cells.
Breast Neoplasms
Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis.
Breast Neoplasms
Impaired expression of Drosha in breast cancer.
Breast Neoplasms
Impaired MicroRNA Processing Facilitates Breast Cancer Cell Invasion by Upregulating Urokinase-Type Plasminogen Activator Expression.
Breast Neoplasms
Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin.
Breast Neoplasms
Loss of Dicer expression is associated with breast cancer progression and recurrence.
Breast Neoplasms
Metastasis suppression: a role of the Dice(r).
Breast Neoplasms
MicroRNA related polymorphisms and breast cancer risk.
Breast Neoplasms
MicroRNAs Link Estrogen Receptor Alpha Status and Dicer Levels in Breast Cancer.
Breast Neoplasms
MiR-18a upregulation decreases Dicer expression and confers paclitaxel resistance in triple negative breast cancer.
Breast Neoplasms
MiR-208a stimulates the cocktail of SOX2 and ?-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1.
Breast Neoplasms
miR-559 polymorphism rs58450758 is linked to breast cancer.
Breast Neoplasms
miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis.
Breast Neoplasms
mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer.
Breast Neoplasms
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Breast Neoplasms
Prognostic significance of deregulated dicer expression in breast cancer.
Breast Neoplasms
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
Breast Neoplasms
Rapid Generation of miRNA Inhibitor Leads by Bioinformatics and Efficient High-Throughput Screening Methods.
Breast Neoplasms
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Breast Neoplasms
Retraction: Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL.
Breast Neoplasms
The Effect of (E)-1-(4'-aminophenyl)-3-phenylprop-2-en-1-one on MicroRNA-18a, Dicer1, and MMP-9 Expressions against DMBA-Induced Breast Cancer.
Breast Neoplasms
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.
Breast Neoplasms
The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
Bronchopulmonary Sequestration
Extending the phenotypes associated with DICER1 mutations.
Carcinogenesis
A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
Carcinogenesis
A novel DICER1 mutation identified in a female with ovarian Sertoli-Leydig cell tumor and multinodular goiter: a case report.
Carcinogenesis
A Positive Feedback Loop Between DICER1 and Differentiation Transcription Factors Is Important for Thyroid Tumorigenesis.
Carcinogenesis
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Carcinogenesis
Aberrant expression of cyclin D1 in cancer.
Carcinogenesis
Absence of DICER1, CTCF, RPL22, DNMT3A, TRRAP, IDH1 and IDH2 hotspot mutations in patients with various subtypes of ovarian carcinomas.
Carcinogenesis
Absence of mature microRNAs inactivates the response of gene expression to carcinogenesis induced by N-ethyl-N-nitrosourea in mouse liver.
Carcinogenesis
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma.
Carcinogenesis
Association between genetic variants in DICER1 and cancer risk: An updated meta-analysis.
Carcinogenesis
Cell survival is dicey without Dicer.
Carcinogenesis
Clinical Characteristics and Mutation Analyses of Ovarian Sertoli-Leydig Cell Tumors.
Carcinogenesis
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Carcinogenesis
Deciphering the Key Features of Malignant Tumor Microenvironment for Anti-cancer Therapy.
Carcinogenesis
Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice.
Carcinogenesis
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Carcinogenesis
Dicer regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1.
Carcinogenesis
Dicer suppresses cytoskeleton remodeling and tumorigenesis of colorectal epithelium by miR-324-5p mediated suppression of HMGXB3 and WASF-2.
Carcinogenesis
Dicer1 functions as a haploinsufficient tumor suppressor.
Carcinogenesis
DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation.
Carcinogenesis
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Carcinogenesis
Down-regulation of Dicer expression in cervical cancer tissues.
Carcinogenesis
Downregulation of Dicer enhances tumor cell proliferation and invasion.
Carcinogenesis
Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma.
Carcinogenesis
Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53 on Drosha complex activity.
Carcinogenesis
Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma.
Carcinogenesis
Expression of Dicer and Its Related MiRNAs in the Progression of Prostate Cancer.
Carcinogenesis
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours.
Carcinogenesis
Germline and somatic DICER1 mutations in familial and sporadic liver tumors.
Carcinogenesis
Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels.
Carcinogenesis
Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree.
Carcinogenesis
Loss of function of Ribonuclease T2, an ancient and phylogenetically conserved RNase, plays a crucial role in ovarian tumorigenesis.
Carcinogenesis
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.
Carcinogenesis
MicroRNA Processing Gene Methylation and Cancer Risk.
Carcinogenesis
MicroRNAs in Neural Stem Cells and Neurogenesis.
Carcinogenesis
MicroRNAs in thyroid development, function and tumorigenesis.
Carcinogenesis
miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma.
Carcinogenesis
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Carcinogenesis
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Carcinogenesis
Predominant DICER1 Pathogenic Variants in Pediatric Follicular Thyroid Carcinomas.
Carcinogenesis
Prognostic significance of Dicer expression in hepatocellular carcinoma.
Carcinogenesis
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
Carcinogenesis
Proliferation and tumorigenesis of a murine sarcoma cell line in the absence of DICER1.
Carcinogenesis
Quantification of thyroid cancer and multinodular goiter risk in the DICER1 syndrome: a family-based cohort study.
Carcinogenesis
Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour.
Carcinogenesis
Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis.
Carcinogenesis
RNF43 mutations are recurrent in Chinese patients with mucinous ovarian carcinoma but absent in other subtypes of ovarian cancer.
Carcinogenesis
Rolling the dice to discover the role of DICER in tumorigenesis.
Carcinogenesis
Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation.
Carcinogenesis
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
Carcinogenesis
Temporal order of RNase IIIb and loss-of-function mutations during development determines phenotype in DICER1 syndrome: a unique variant of the two-hit tumor suppression model.
Carcinogenesis
The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activities.
Carcinogenesis
The paradox of dicer in cancer.
Carcinogenesis
The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment.
Carcinogenesis
The role of dicer in DNA damage repair.
Carcinogenesis
Unique Haploinsufficient Role of the MicroRNA-Processing Molecule Dicer1 in a Murine Colitis-Associated Tumorigenesis Model.
Carcinoma
A low dicer expression is associated with resistance to 5-FU-based chemoradiotherapy and a shorter overall survival in patients with oral squamous cell carcinoma.
Carcinoma
A precursor microRNA in a cancer cell nucleus: Get me out of here!
Carcinoma
Absence of DICER1, CTCF, RPL22, DNMT3A, TRRAP, IDH1 and IDH2 hotspot mutations in patients with various subtypes of ovarian carcinomas.
Carcinoma
Altered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients.
Carcinoma
An NF90/NF110-mediated feedback amplification loop regulates dicer expression and controls ovarian carcinoma progression.
Carcinoma
Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.
Carcinoma
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma.
Carcinoma
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Carcinoma
Development of a metastatic fluorescent Lewis Lung carcinoma mouse model: identification of mRNAs and microRNAs involved in tumor invasion.
Carcinoma
Diagnostic and Prognostic Potential of MicroRNA Maturation Regulators Drosha, AGO1 and AGO2 in Urothelial Carcinomas of the Bladder.
Carcinoma
Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells.
Carcinoma
Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice.
Carcinoma
Dicer is down-regulated in clear cell renal cell carcinoma and in vitro Dicer knockdown enhances malignant phenotype transformation.
Carcinoma
Dicer protein levels elevated by mild hyperthermia promote a pro-survival phenotype.
Carcinoma
Dicer Sequencing, Whole Genome Methylation Profiling, mRNA and smallRNA Sequencing Analysis in Basal Cell Carcinoma.
Carcinoma
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Carcinoma
Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2?.
Carcinoma
DICER1 mutations are frequent in adolescent-onset papillary thyroid carcinoma.
Carcinoma
DICER1 syndrome can mimic different genetic tumor predispositions.
Carcinoma
Down-regulation of Dicer in hepatocellular carcinoma.
Carcinoma
Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer.
Carcinoma
Dysregulation of the miRNA biogenesis components DICER1, DROSHA, DGCR8 and AGO2 in clear cell renal cell carcinoma in both a Korean cohort and the cancer genome atlas kidney clear cell carcinoma cohort.
Carcinoma
EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.
Carcinoma
Expression of the microRNA regulators Drosha, Dicer and Ago2 in non-small cell lung carcinomas.
Carcinoma
Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles.
Carcinoma
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours.
Carcinoma
Generation of Self-Inhibitory Recombinant Viral Hemorrhagic Septicemia Virus (VHSV) by Insertion of Viral P Gene-Targeting Artificial MicroRNA into Viral Genome and Effect of Dicer Gene Knockout on the Recombinant VHSV Replication.
Carcinoma
Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma.
Carcinoma
Genetic profiling of rhabdomyosarcoma with clinicopathological and radiological correlation.
Carcinoma
Genetic variants in RAN, DICER and HIWI of microRNA biogenesis genes and risk of cervical carcinoma in a Chinese population.
Carcinoma
Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels.
Carcinoma
Gynecological lesions in hereditary cancer predisposition syndromes.
Carcinoma
Hereditary ovarian tumour syndromes: current update on genetics and imaging.
Carcinoma
High-grade serous ovarian cancer arises from fallopian tube in a mouse model.
Carcinoma
Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder.
Carcinoma
Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma.
Carcinoma
MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.
Carcinoma
Metachronous anaplastic sarcoma of the kidney and thyroid follicular carcinoma as manifestations of DICER1 abnormalities.
Carcinoma
miR-122 Promotes Metastasis of Clear-Cell Renal Cell Carcinoma by Downregulating Dicer.
Carcinoma
miRNA profiling along tumor progression in ovarian carcinoma.
Carcinoma
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Carcinoma
Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells.
Carcinoma
Overexpression of Dicer in precursor lesions of lung adenocarcinoma.
Carcinoma
Pediatric Renal Tumors: Updates in the Molecular Era.
Carcinoma
Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins.
Carcinoma
Prognostic significance of Dicer expression in ovarian cancer-link to global microRNA changes and oestrogen receptor expression.
Carcinoma
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Carcinoma
RNF43 mutations are recurrent in Chinese patients with mucinous ovarian carcinoma but absent in other subtypes of ovarian cancer.
Carcinoma
Role of Epithelial-Mesenchyme Transition in Chlamydia Pathogenesis.
Carcinoma
Sertoli-Leydig cell tumor, thyroid follicular carcinoma and rhabdomyosarcoma of the uterine cervix in a prepubertal girl with pathogenic germline variant in DICER1 gene.
Carcinoma
Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma.
Carcinoma
Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.
Carcinoma
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Carcinoma
Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma.
Carcinoma
[A negative correlation between Drosha expression and gastric adenocarcinoma malignancy and invasion].
Carcinoma, Basal Cell
Dicer Sequencing, Whole Genome Methylation Profiling, mRNA and smallRNA Sequencing Analysis in Basal Cell Carcinoma.
Carcinoma, Basal Cell
DICER1 syndrome can mimic different genetic tumor predispositions.
Carcinoma, Basal Cell
Gynecological lesions in hereditary cancer predisposition syndromes.
Carcinoma, Basal Cell
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Carcinoma, Ductal
The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
Carcinoma, Hepatocellular
A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT.
Carcinoma, Hepatocellular
Ablation of Dicer leads to widespread perturbation of signaling pathways.
Carcinoma, Hepatocellular
Corrigendum to "Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells" [383 (2016) 282-294].
Carcinoma, Hepatocellular
Down-regulation of Dicer in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Genetic variant in DICER gene is associated with prognosis of hepatocellular carcinoma in a Chinese cohort.
Carcinoma, Hepatocellular
Germline and somatic DICER1 mutations in familial and sporadic liver tumors.
Carcinoma, Hepatocellular
Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1? and epithelial-mesenchymal transition.
Carcinoma, Hepatocellular
microRNA-18a Promotes Cell Migration and Invasion Through Inhibiting Dicer l Expression in Hepatocellular Carcinoma In Vitro.
Carcinoma, Hepatocellular
Prognostic significance of Dicer expression in hepatocellular carcinoma.
Carcinoma, Hepatocellular
RNA-binding protein AUF1 suppresses miR-122 biogenesis by down-regulating Dicer1 in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Carcinoma, Hepatocellular
Variation in the Dicer and RAN Genes Are Associated with Survival in Patients with Hepatocellular Carcinoma.
Carcinoma, Intraductal, Noninfiltrating
Loss of Dicer expression is associated with breast cancer progression and recurrence.
Carcinoma, Intraductal, Noninfiltrating
The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
Carcinoma, Lewis Lung
Development of a metastatic fluorescent Lewis Lung carcinoma mouse model: identification of mRNAs and microRNAs involved in tumor invasion.
Carcinoma, Mucoepidermoid
Mucoepidermoid carcinoma of upper aerodigestive tract: clinicopathologic study of 78 cases with immunohistochemical analysis of Dicer expression.
Carcinoma, Non-Small-Cell Lung
Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
DICER activates autophagy and promotes cisplatin resistance in non-small cell lung cancer by binding with let-7i-5p.
Carcinoma, Non-Small-Cell Lung
DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.
Carcinoma, Non-Small-Cell Lung
Prognostic value of the MicroRNA regulators Dicer and Drosha in non-small-cell lung cancer: co-expression of Drosha and miR-126 predicts poor survival.
Carcinoma, Non-Small-Cell Lung
Reduced expression of Dicer associated with poor prognosis in lung cancer patients.
Carcinoma, Ovarian Epithelial
Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression.
Carcinoma, Ovarian Epithelial
Dicer affects cisplatin?mediated apoptosis in epithelial ovarian cancer cells.
Carcinoma, Ovarian Epithelial
Dicer, Drosha, and outcomes in patients with ovarian cancer.
Carcinoma, Ovarian Epithelial
miR-98-5p contributes to cisplatin resistance in epithelial ovarian cancer by suppressing miR-152 biogenesis via targeting Dicer1.
Carcinoma, Ovarian Epithelial
The dicey role of Dicer: implications for RNAi therapy.
Carcinoma, Renal Cell
Dicer is down-regulated in clear cell renal cell carcinoma and in vitro Dicer knockdown enhances malignant phenotype transformation.
Carcinoma, Renal Cell
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Carcinoma, Renal Cell
Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2?.
Carcinoma, Renal Cell
Dysregulation of the miRNA biogenesis components DICER1, DROSHA, DGCR8 and AGO2 in clear cell renal cell carcinoma in both a Korean cohort and the cancer genome atlas kidney clear cell carcinoma cohort.
Carcinoma, Renal Cell
Gynecological lesions in hereditary cancer predisposition syndromes.
Carcinoma, Renal Cell
miR-122 Promotes Metastasis of Clear-Cell Renal Cell Carcinoma by Downregulating Dicer.
Carcinoma, Renal Cell
Pediatric Renal Tumors: Updates in the Molecular Era.
Carcinoma, Renal Cell
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Carcinoma, Renal Cell
Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.
Carcinoma, Renal Cell
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Carcinoma, Small Cell
Hereditary ovarian tumour syndromes: current update on genetics and imaging.
Carcinoma, Squamous Cell
Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles.
Carcinoma, Squamous Cell
Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels.
Carcinoma, Squamous Cell
Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells.
Carcinoma, Squamous Cell
Overexpression of Dicer in precursor lesions of lung adenocarcinoma.
Carcinoma, Squamous Cell
Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma.
Carcinoma, Transitional Cell
Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer.
Carcinosarcoma
A rare malignant thyroid carcinosarcoma with aggressive behavior and DICER1 gene mutation: a case report with literature review.
Carcinosarcoma
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Carcinosarcoma
DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation.
Carcinosarcoma
Mutational and Immunophenotypic Profiling of a Series of 8 Tubo-ovarian Carcinosarcomas Revealed a Monoclonal Origin of the Disease.
Cardiomyopathies
Differential Expression of Dicer, miRNAs, and Inflammatory Markers in Diabetic Ins2+/- Akita Hearts.
Cardiomyopathies
miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca(2+) signaling.
Cardiomyopathies
Suppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac Dysfunction.
Cardiomyopathy, Dilated
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure.
Cardiovascular Abnormalities
Loss of MicroRNAs in Neural Crest Leads to Cardiovascular Syndromes Resembling Human Congenital Heart Defects.
Cardiovascular Diseases
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Cardiovascular Diseases
MicroRNAs Are Involved in Homocysteine-Induced Cardiac Remodeling.
Carney Complex
Familial non-medullary thyroid cancer: unraveling the genetic maze.
Carney Complex
Familial non-medullary thyroid carcinoma: clinico-pathological features, current knowledge and novelty regarding genetic risk factors.
Carney Complex
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Carney Complex
The clinical aspects of pituitary tumour genetics.
Cerebellar Neoplasms
Loss of H3K27me3 and nuclear expression of TLE1 in primary intracranial sarcoma, DICER1-mutant.
Cholangiocarcinoma
CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma.
Cholangiocarcinoma
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Choroidal Neovascularization
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.
Cleft Lip
Genetic variants of microRNA processing genes and risk of non-syndromic orofacial clefts.
Colitis
Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice.
Colitis
Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis.
Colonic Neoplasms
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.
Colonic Neoplasms
A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.
Colonic Neoplasms
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Colonic Neoplasms
Dicer regulates non-homologous end joining and is associated with chemosensitivity in colon cancer patients.
Colonic Neoplasms
DICER1 and PRKRA in Colon Adenocarcinoma.
Colonic Neoplasms
Dicer1 Promotes Colon Cancer Cell Invasion and Migration Through Modulation of tRF-20-MEJB5Y13 Expression Under Hypoxia.
Colonic Neoplasms
Impaired DICER1 function promotes stemness and metastasis in colon cancer.
Colonic Neoplasms
Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4A(DCAF1) to promote colon cancer development.
Colonic Neoplasms
Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs.
Colonic Neoplasms
Regulation of coagulation factor XI expression by microRNAs in the human liver.
Colonic Neoplasms
Role of Dicer in regulating oxaliplatin resistance of colon cancer cells.
Colorectal Neoplasms
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.
Colorectal Neoplasms
A distinct expression pattern of the long 3'-untranslated region dicer mRNA and its implications for posttranscriptional regulation in colorectal cancer.
Colorectal Neoplasms
Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.
Colorectal Neoplasms
Clinicopathological and prognostic significance of the microRNA processing enzyme DICER1 mRNA expression in colorectal cancer patients.
Colorectal Neoplasms
Dicer 1, ribonuclease type III modulates a reprogramming effect in colorectal cancer cells.
Colorectal Neoplasms
Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients.
Colorectal Neoplasms
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Colorectal Neoplasms
Dicer suppresses cytoskeleton remodeling and tumorigenesis of colorectal epithelium by miR-324-5p mediated suppression of HMGXB3 and WASF-2.
Colorectal Neoplasms
DICER1-AS1 Promotes the Malignant Behaviors of Colorectal Cancer Cells by Regulating miR-296-5p/STAT3 Axis.
Colorectal Neoplasms
Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A?>?G Polymorphism Relative to Colorectal Cancer Risk.
Colorectal Neoplasms
Differences in the Drosha and Dicer Cleavage Profiles in Colorectal Cancer and Normal Colon Tissue Samples.
Colorectal Neoplasms
Down-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancer.
Colorectal Neoplasms
Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer.
Colorectal Neoplasms
Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas.
Colorectal Neoplasms
Impaired DICER1 function promotes stemness and metastasis in colon cancer.
Colorectal Neoplasms
MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN.
Colorectal Neoplasms
MicroRNA-143 is a putative predictive factor for the response to fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer.
Colorectal Neoplasms
miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma.
Colorectal Neoplasms
Overexpression of Dicer predicts poor survival in colorectal cancer.
Colorectal Neoplasms
Single-nucleotide polymorphisms of microRNA processing machinery genes and risk of colorectal cancer.
Colorectal Neoplasms
The colorectal microRNAome.
Colorectal Neoplasms, Hereditary Nonpolyposis
Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs.
Colorectal Neoplasms, Hereditary Nonpolyposis
The clinical aspects of pituitary tumour genetics.
Coronary Artery Disease
Influence of genetic polymorphisms in DICER and XPO5 genes on the risk of coronary artery disease and circulating levels of vascular miRNAs.
Costello Syndrome
Germline predisposition to genitourinary rhabdomyosarcoma.
COVID-19
The relative expression of miR-31, miR-29, miR-126, and miR-17 and their mRNA targets in the serum of COVID-19 patients with different grades during hospitalization.
Cystadenoma, Papillary
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Cysts
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Cysts
Current Management of Pleuropulmonary Blastoma: A Surgical Perspective.
Cysts
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility.
Cysts
Diagnosis and Treatment of Pleuropulmonary Blastoma in Children: A Single-Center Report of 41 Cases.
Cysts
Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney.
Cysts
DICER1 mutations in twelve Chinese patients with pleuropulmonary blastoma.
Cysts
Evolution of Renal Cysts to Anaplastic Sarcoma of Kidney in a Child With DICER1 Syndrome.
Cysts
Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome.
Cysts
Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma.
Cysts
Hotspot mutations in DICER1 causing GLOW Syndrome-associated macrocephaly via modulation of specific microRNA populations results in activation of PI3K/ATK/mTOR signaling.
Cysts
Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation.
Cysts
Lung cyst and multinodular thyroid goiter: Keys to DICER1 syndrome diagnosis in a 16-year-old female.
Cysts
MicroRNAs regulate renal tubule maturation through modulation of Pkd1.
Cysts
Multiple DICER1-related tumors in a child with a large interstitial 14q32 deletion.
Cysts
Mutiple DICER1-related lesions associated with a germline deep intronic mutation.
Cysts
Stem cell division is regulated by the microRNA pathway.
Cysts
Unraveling the Mechanistic Complexity of the Glomerulocystic Phenotype in Dicer Conditional KO Mice by 2D Gel Electrophoresis Coupled Mass Spectrometry.
Cysts
Unusual phenotypes in patients with a pathogenic germline variant in DICER1.
Demyelinating Diseases
Dicer ablation in oligodendrocytes provokes neuronal impairment in mice.
Demyelinating Diseases
Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination.
Demyelinating Diseases
The deletion of dicer in mature myelinating glial cells causes progressive axonal degeneration but not overt demyelination in adult mice.
Dengue
Drosha, DGCR8, and Dicer mRNAs are down-regulated in human cells infected with dengue virus 4, and play a role in viral pathogenesis.
Dengue
Letter to the Editor "Drosha, DGCR8, and Dicer mRNAs are downregulated in human cells infected with dengue virus 4" - Genet. Mol. Res. 15 (2): gmr.15027891 - Drosha, Dicer, and TRBP mRNA are downregulated in Vero cells with the 3'UTR of Dengue virus.
Dengue
Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti.
Dengue
Role of RNA interference (RNAi) in dengue virus replication and identification of NS4B as an RNAi suppressor.
Dengue
Specificity of resistance to dengue virus isolates is associated with genotypes of the mosquito antiviral gene Dicer-2.
Dermatitis, Atopic
Aggravated TSLP-Induced Atopic Dermatitis in Mice Lacking Dicer in Adult Skin Keratinocytes.
Diabetes Mellitus
Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population.
Diabetes Mellitus
Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.
Diabetes Mellitus
Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence.
Diabetes Mellitus, Type 2
Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population.
Diabetes Mellitus, Type 2
Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.
Diabetes, Gestational
Upregulation of microRNA processing enzymes Drosha and Dicer in gestational diabetes mellitus.
Diabetic Angiopathies
Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population.
Diabetic Cardiomyopathies
Differential Expression of Dicer, miRNAs, and Inflammatory Markers in Diabetic Ins2+/- Akita Hearts.
DiGeorge Syndrome
'Black sheep' that don't leave the double-stranded RNA-binding domain fold.
DiGeorge Syndrome
A microRNA expression signature of osteoclastogenesis.
DiGeorge Syndrome
CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17.
DiGeorge Syndrome
Complexity in Regulation of microRNA Machinery Components in Invasive Breast Carcinoma.
DiGeorge Syndrome
Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation.
DiGeorge Syndrome
DGCR8-dependent efficient pri-miRNA processing of human pri-miR-9-2.
DiGeorge Syndrome
Distinct requirements of microRNAs in NK cell activation, survival, and function.
DiGeorge Syndrome
Endo-siRNA deficiency results in oocyte maturation failure and apoptosis in porcine oocytes.
DiGeorge Syndrome
Expression of DGCR8-Dependent MicroRNAs Is Indispensable for Osteoclastic Development and Bone-Resorbing Activity.
DiGeorge Syndrome
In vitro and in vivo assays for the activity of drosha complex.
DiGeorge Syndrome
MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex.
DiGeorge Syndrome
MicroRNA biogenesis and cancer.
DiGeorge Syndrome
MicroRNA biogenesis: isolation and characterization of the microprocessor complex.
DiGeorge Syndrome
MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice.
DiGeorge Syndrome
Noncanonical functions of microRNA pathway enzymes - Drosha, DGCR8, Dicer and Ago proteins.
DiGeorge Syndrome
Overexpression of Drosha, DiGeorge syndrome critical region gene 8 (DGCR8), and Dicer mRNAs in the pathogenesis of psoriasis.
DiGeorge Syndrome
Overexpression of microRNA biogenesis machinery: Drosha, DGCR8 and Dicer in multiple sclerosis patients.
DiGeorge Syndrome
Processing of microRNA primary transcripts requires heme in mammalian cells.
DiGeorge Syndrome
Processing of virus-derived cytoplasmic primary-microRNAs.
DiGeorge Syndrome
RNA Genes: Retroelements and Virally Retroposable microRNAs in Human Embryonic Stem Cells.
DiGeorge Syndrome
The Microprocessor complex mediates the genesis of microRNAs.
Double Outlet Right Ventricle
Loss of MicroRNAs in Neural Crest Leads to Cardiovascular Syndromes Resembling Human Congenital Heart Defects.
Double Outlet Right Ventricle
miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septation.
Embolism
The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21.
Encephalitis
Increased Viral Dissemination in the Brain and Lethality in MCMV-Infected, Dicer-Deficient Neonates.
Encephalomyelitis
The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression.
Encephalomyelitis, Autoimmune, Experimental
The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression.
Encephalomyelitis, Venezuelan Equine
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Enchondromatosis
Genetics and genomics of ovarian sex cord-stromal tumors.
Endodermal Sinus Tumor
An Unusual Enteric Yolk Sac Tumor: First Report of an Ovarian Germ Cell Tumor Associated With a Germline Pathogenic Variant in DICER1.
Endometrial Neoplasms
Dicer1 dysfunction promotes stemness and aggression in endometrial carcinoma.
Endometrial Neoplasms
DICER1 expression and outcomes in endometrioid endometrial adenocarcinoma.
Endometrial Neoplasms
DICER1 regulates endometrial carcinoma invasion via histone acetylation and methylation.
Endometrial Neoplasms
Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer.
Endometrial Neoplasms
Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer.
Endometrial Neoplasms
MicroRNA as Epigenetic Modifiers in Endometrial Cancer: A Systematic Review.
Endometrial Neoplasms
miR-130b is an EMT-related microRNA that targets DICER1 for aggression in endometrial cancer.
Endometrial Neoplasms
Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma.
Endometrial Neoplasms
Reduced DICER1 Elicits an Interferon Response in Endometrial Cancer Cells.
Endometrial Neoplasms
The prevalence of germline DICER1 pathogenic variation in cancer populations.
Endometriosis
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.
Endometriosis
Molecular evidence for differences in endometrium in severe versus mild endometriosis.
Enzootic Bovine Leukosis
Identification of tri-phosphatase activity in the biogenesis of retroviral microRNAs and RNAP III-generated shRNAs.
Epilepsy
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.
Epilepsy, Temporal Lobe
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.
Esophageal Neoplasms
miR326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression.
Esophageal Squamous Cell Carcinoma
Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma.
Eye Diseases
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation.
Fanconi Anemia
Dicer prevents genome instability in response to replication stress.
Fanconi Anemia
Recent advances in Wilms tumor predisposition.
Fatty Liver
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis.
Fibrosarcoma
Genomics of a pediatric ovarian fibrosarcoma. Association with the DICER1 syndrome.
Fibrosarcoma
Primary Lung Tumors in Children: Radiologic-Pathologic Correlation From the Radiologic Pathology Archives.
Fibrous Dysplasia, Polyostotic
An update on the genetics of benign pituitary adenomas in children and adolescents.
Fibrous Dysplasia, Polyostotic
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Fibrous Dysplasia, Polyostotic
The clinical aspects of pituitary tumour genetics.
Foot-and-Mouth Disease
Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P.
Fragile X Syndrome
Involvement of FMRP in Primary MicroRNA Processing via Enhancing Drosha Translation.
Fragile X Syndrome
The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer.
Frontotemporal Dementia
Drosha Inclusions Are New Components of Dipeptide-Repeat Protein Aggregates in FTLD-TDP and ALS C9orf72 Expansion Cases.
Frontotemporal Lobar Degeneration
Drosha Inclusions Are New Components of Dipeptide-Repeat Protein Aggregates in FTLD-TDP and ALS C9orf72 Expansion Cases.
Gardner Syndrome
Familial non-medullary thyroid cancer: unraveling the genetic maze.
Gastritis
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Gastrointestinal Neoplasms
Serum Exosomal Dicer Is a Useful Biomarker for Early Detection of Differentiated Gastric Adenocarcinoma.
Genetic Diseases, Inborn
DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1-associated sarcoma.
Genetic Diseases, Inborn
DICER1 Syndrome: DICER1 Mutations in Rare Cancers.
Genetic Diseases, Inborn
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Genetic Diseases, Inborn
Primary Biphasic Hepatic Sarcoma in DICER1 Syndrome.
Genetic Diseases, Inborn
Secondary Sarcomas: Biology, Presentation, and Clinical Care.
Genetic Diseases, Inborn
Surveillance recommendations for DICER1 pathogenic variant carriers: a report from the SIOPE Host Genome Working Group and CanGene-CanVar Clinical Guideline Working Group.
Geographic Atrophy
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Geographic Atrophy
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation.
Geographic Atrophy
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.
Geographic Atrophy
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.
Geographic Atrophy
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
Geographic Atrophy
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Geographic Atrophy
ERK1/2 activation is a therapeutic target in age-related macular degeneration.
Geographic Atrophy
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy.
Glioblastoma
DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma.
Glioblastoma
Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.
Glioblastoma
MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.
Glioblastoma
miRNA-independent function of long noncoding pri-miRNA loci.
Glioblastoma
Regulation of p27Kip1 by miRNA 221/222 in glioblastoma.
Glioblastoma
The nuclear DICER-circular RNA complex drives the deregulation of the glioblastoma cell microRNAome.
Glioblastoma
The QKI-5 and QKI-6 RNA Binding Proteins Regulate the Expression of MicroRNA 7 in Glial Cells.
Glioblastoma
[The effect of silencing Dicer by small interferance RNA on the biological characteristics of human glioma cells.]
Glioma
DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma.
Glioma
Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.
Glioma
[The effect of silencing Dicer by small interferance RNA on the biological characteristics of human glioma cells.]
Goiter
A family with Sertoli-Leydig cell tumour, multinodular goiter, and DICER1 mutation.
Goiter
A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype.
Goiter
A novel DICER1 mutation identified in a female with ovarian Sertoli-Leydig cell tumor and multinodular goiter: a case report.
Goiter
DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.
Goiter
DICER1 mutations in a patient with an ovarian Sertoli-Leydig tumor, well-differentiated fetal adenocarcinoma of the lung, and familial multinodular goiter.
Goiter
DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors.
Goiter
DICER1 Syndrome and Cancer Predisposition: From a Rare Pediatric Tumor to Lifetime Risk.
Goiter
DICER1 syndrome can mimic different genetic tumor predispositions.
Goiter
Extending the phenotypes associated with DICER1 mutations.
Goiter
Familial multinodular goiter and Sertoli-Leydig cell tumors associated with a large intragenic in-frame
Goiter
Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides.
Goiter
Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree.
Goiter
Intrathyroidal Thymus (Incidentaloma) Mimicking Thyroid Neoplasia in DICER1 Syndrome.
Goiter
Lung cyst and multinodular thyroid goiter: Keys to DICER1 syndrome diagnosis in a 16-year-old female.
Goiter
MicroRNAs in thyroid development, function and tumorigenesis.
Goiter
Multinodular Goiter in Children: an Important Pointer to a Germline DICER1 Mutation.
Goiter
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Goiter
Mutiple DICER1-related lesions associated with a germline deep intronic mutation.
Goiter
Novel DICER1 mutation as cause of multinodular goiter in children.
Goiter
Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome.
Goiter
Ovarian Sertoli-Leydig Cell Tumor, Multinodular Goiter, Cystic Nephromas and DICER1 Mutations: Case Report and Literature Review.
Goiter
Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry.
Goiter
Prevalence and Spectrum of DICER1 Mutations in Adult-onset Thyroid Nodules with Indeterminate Cytology.
Goiter
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Goiter
Quantification of thyroid cancer and multinodular goiter risk in the DICER1 syndrome: a family-based cohort study.
Goiter
Selective dicer suppression in the kidney alters GSK3?/?-catenin pathways promoting a glomerulocystic disease.
Goiter
THYROCYTE-SPECIFIC DICER1 DEFICIENCY ALTERS THYROID FOLLICULAR ORGANIZATION AND PREVENTS GOITER DEVELOPMENT.
Goiter
Unusual phenotypes in patients with a pathogenic germline variant in DICER1.
Goiter
[Hereditary predispositions to follicular thyroid tumors].
Granulosa Cell Tumor
An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors.
Granulosa Cell Tumor
DICER1 hot-spot mutations in ovarian gynandroblastoma.
Granulosa Cell Tumor
Ovarian sex cord-stromal tumours: an update in recent molecular advances.
Granulosa Cell Tumor
Practical roles for molecular diagnostic testing in ovarian adult granulosa cell tumour, Sertoli-Leydig cell tumour, microcystic stromal tumour and their mimics.
Granulosa Cell Tumor
Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors.
Granulosa Cell Tumor
Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.
Granulosa Cell Tumor
[Application of molecular analysis in differential diagnosis of ovarian adult granulosa cell tumors].
Graves Disease
DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.
Hamartoma
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Hamartoma
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Hamartoma
Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides.
Hamartoma
Imaging of DICER1 syndrome.
Hamartoma
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Hamartoma
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome. Reply.
Hamartoma
Nasal chondromesenchymal hamartomas arise secondary to germline and somatic mutations of DICER1 in the pleuropulmonary blastoma tumor predisposition disorder.
Hamartoma
Nasal chondromesenchymal hamartomas in a cohort with pathogenic germline variation in DICER1.
Hamartoma
Pleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome.
Hamartoma
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Hamartoma
THE "-OMAS" and "-OPIAS": Targeted and Philosophical Considerations Regarding Hamartomas, Choristomas, Teratomas, Ectopias, and Heterotopias in Pediatric Otorhinolaryngologic Pathology.
Hamartoma Syndrome, Multiple
A Case Report of Syndromic Multinodular Goitre in Adolescence: Exploring the Phenotype Overlap between Cowden and DICER1 Syndromes.
Hamartoma Syndrome, Multiple
Familial non-medullary thyroid cancer: unraveling the genetic maze.
Hamartoma Syndrome, Multiple
Familial non-medullary thyroid carcinoma: clinico-pathological features, current knowledge and novelty regarding genetic risk factors.
Hamartoma Syndrome, Multiple
Gynecological lesions in hereditary cancer predisposition syndromes.
Hamartoma Syndrome, Multiple
High Prevalence of DICER1 Mutations and Low Frequency of Gene Fusions in Pediatric Follicular-Patterned Tumors of the Thyroid.
Hamartoma Syndrome, Multiple
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Hamartoma Syndrome, Multiple
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Hearing Loss, Sensorineural
Dicer Is Down-regulated and Correlated with Drosha in Idiopathic Sudden Sensorineural Hearing Loss.
Heart Defects, Congenital
Individual and joint effects of genetic polymorphisms in microRNA-machinery genes on congenital heart disease susceptibility.
Heart Diseases
ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis.
Heart Diseases
MicroRNAs as a therapeutic target for cardiovascular diseases.
Heart Failure
Differential Expression of Dicer, miRNAs, and Inflammatory Markers in Diabetic Ins2+/- Akita Hearts.
Heart Failure
MicroRNAs as a therapeutic target for cardiovascular diseases.
Heart Failure
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure.
Heart Septal Defects, Ventricular
Loss of MicroRNAs in Neural Crest Leads to Cardiovascular Syndromes Resembling Human Congenital Heart Defects.
Heart Septal Defects, Ventricular
miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septation.
Hemangiosarcoma
Biallelic Dicer1 loss mediated by aP2-Cre drives angiosarcoma.
Hematologic Neoplasms
Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis.
Hematologic Neoplasms
Stop the dicing in hematopoiesis: What have we learned?
Hemorrhagic Septicemia, Viral
Generation of Self-Inhibitory Recombinant Viral Hemorrhagic Septicemia Virus (VHSV) by Insertion of Viral P Gene-Targeting Artificial MicroRNA into Viral Genome and Effect of Dicer Gene Knockout on the Recombinant VHSV Replication.
Hemorrhagic Septicemia, Viral
Species specific inhibition of viral replication using dicer substrate siRNAs (DsiRNAs) targeting the viral nucleoprotein of the fish pathogenic rhabdovirus viral hemorrhagic septicemia virus (VHSV).
Hepatitis
Outcome of two pairs of monozygotic twins with pleuropulmonary blastoma: case report.
Hepatitis
Resistance of human hepatitis delta virus RNAs to dicer activity.
Hepatitis B
Correlation between hepatitis B virus protein and microRNA processor Drosha in cells expressing HBV.
Hepatitis B
MicroRNA-581 promotes hepatitis B virus surface antigen expression by targeting Dicer and EDEM1.
Hepatitis C
Dual regulation of hepatitis C viral RNA by cellular RNAi requires partitioning of Ago2 to lipid droplets and P-bodies.
Hepatitis C
Evaluation of Canonical siRNA and Dicer Substrate RNA for Inhibition of Hepatitis C Virus Genome Replication - A Comparative Study.
Hepatitis C
Refractoriness of hepatitis C virus internal ribosome entry site to processing by Dicer in vivo.
Hepatitis C
RNase III cleavage demonstrates a long range RNA: RNA duplex element flanking the hepatitis C virus internal ribosome entry site.
Herpes Simplex
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Hidradenitis Suppurativa
Inflammation induced changes in the expression levels of components of the microRNA maturation machinery Drosha, Dicer, Drosha co-factor DGRC8 and Exportin-5 in inflammatory lesions of hidradenitis suppurativa patients.
Hip Dislocation
Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies.
HIV-Associated Lipodystrophy Syndrome
Role of microRNA biogenesis in adipocyte and lipodystrophy.
Hodgkin Disease
Hodgkin lymphoma as a novel presentation of familial DICER1 syndrome.
Hodgkin Disease
Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo.
Hodgkin Disease
Whole genome sequencing reveals DICER1 as a candidate predisposing gene in familial Hodgkin lymphoma.
Huntington Disease
Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases.
Huntington Disease
Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets.
Hydronephrosis
Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation.
Hypercalcemia
Micro-RNAs in the parathyroid: a new portal in understanding secondary hyperparathyroidism.
Hypertension
3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.
Hypertension
rs10719 Polymorphism Located within DROSHA 3'-Untranslated Region is Responsible for Development of Primary Hypertension by Disrupting Binding with microRNA-27b.
Hypertension, Pregnancy-Induced
Genetic variants in DICER1, DROSHA, RAN, and XPO5 genes and risk of pregnancy-induced hypertension.
Hypertriglyceridemia
Altered pattern of circulating miRNAs in HIV lipodystrophy perturbs key adipose differentiation and inflammation pathways.
Hypocalcemia
Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia.
Hypocalcemia
Post-transcriptional mechanisms regulating parathyroid hormone gene expression in secondary hyperparathyroidism.
Hypothyroidism
Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations.
Hypothyroidism
The microRNA-processing enzyme Dicer is essential for thyroid function.
Hypothyroidism
THYROCYTE-SPECIFIC DICER1 DEFICIENCY ALTERS THYROID FOLLICULAR ORGANIZATION AND PREVENTS GOITER DEVELOPMENT.
Idiopathic Pulmonary Fibrosis
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.
Immune System Diseases
MHC class II regulation by epigenetic agents and microRNAs.
Infarction, Middle Cerebral Artery
Transient focal ischemia induces extensive temporal changes in rat cerebral microRNAome.
Infections
A Glimpse of "Dicer Biology" Through the Structural and Functional Perspective.
Infections
A single Argonaute gene is required for induction of RNA silencing antiviral defense and promotes viral RNA recombination.
Infections
Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination.
Infections
Alteration of Escherichia coli RNase D by infection with bacteriophage T4.
Infections
An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections.
Infections
An Ascovirus-encoded RNase III autoregulates its expression and suppresses RNA interference-mediated gene silencing.
Infections
Antiviral RNA interference in mammalian cells.
Infections
Characterization of hypovirus-derived small RNAs generated in the chestnut blight fungus by an inducible DCL-2-dependent pathway.
Infections
Cleavage of Dicer protein by I7 protease during vaccinia virus infection.
Infections
Comprehensive analysis of full genome sequence and Bd-milRNA/target mRNAs to discover the mechanism of hypovirulence in Botryosphaeria dothidea strains on pear infection with BdCV1 and BdPV1.
Infections
Comprehensive characterization of viral miRNAs involved in white spot syndrome virus (WSSV) infection.
Infections
Cross-species comparative analysis of Dicer proteins during Sindbis virus infection.
Infections
Cytoplasmic RNA viruses as potential vehicles for the delivery of therapeutic small RNAs.
Infections
Deregulation of Type I IFN-Dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice.
Infections
Development of a new duplex real-time polymerase chain reaction assay for detection of dicer in G. gallus.
Infections
Dicer regulates Nosema ceranae proliferation in honey bees.
Infections
Dicer-2 processes diverse viral RNA species.
Infections
Dicer-2- and Piwi-mediated RNA interference in Rift Valley fever virus-infected mosquito cells.
Infections
Dicing with viruses: microRNAs as antiviral factors.
Infections
Differential Expression of Six Rnase2 and Three Rnase3 Paralogs Identified in Blunt Snout Bream in Response to Aeromonas hydrophila Infection.
Infections
Differential expression of small RNA pathway genes associated with the Biomphalaria glabrata/Schistosoma mansoni interaction.
Infections
Discovery of Two Mycoviruses by High-Throughput Sequencing and Assembly of Mycovirus-Derived Small Silencing RNAs From a Hypovirulent Strain of Sclerotinia sclerotiorum.
Infections
Drosha, DGCR8, and Dicer mRNAs are down-regulated in human cells infected with dengue virus 4, and play a role in viral pathogenesis.
Infections
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression.
Infections
Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2.
Infections
Enhanced Oncolytic Activities of the Telomerase-Specific Replication-Competent Adenovirus Expressing Short-Hairpin RNA against Dicer.
Infections
Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila.
Infections
Evidence for a cytoplasmic microprocessor of pri-miRNAs.
Infections
Evidence for Host Epigenetic Signatures Arising From Arbovirus Infections: A Systematic Review.
Infections
Evidence that RNA silencing functions as an antiviral defense mechanism in fungi.
Infections
Genetic variability and evolutionary implications of RNA silencing suppressor genes in RNA1 of sweet potato chlorotic stunt virus isolates infecting sweetpotato and related wild species.
Infections
HIV-1 infection increases microRNAs that inhibit Dicer1, HRB and HIV-EP2, thereby reducing viral replication.
Infections
Human Antimicrobial RNases Inhibit Intracellular Bacterial Growth and Induce Autophagy in Mycobacteria-Infected Macrophages.
Infections
Human DICER helicase domain recruits PKR and modulates its antiviral activity.
Infections
Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model.
Infections
Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.
Infections
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression.
Infections
Immune signaling pathways activated in response to different pathogenic micro-organisms in Bombyx mori.
Infections
Infections of virulent and avirulent viruses differentially influenced the expression of dicer-1, ago-1, and microRNAs in Bombus terrestris.
Infections
In vivo study of Dicer-2-mediated immune response of the small interfering RNA pathway upon systemic infections of virulent and avirulent viruses in Bombus terrestris.
Infections
KSHV RNA-binding protein ORF57 inhibits P-body formation to promote viral multiplication by interaction with Ago2 and GW182.
Infections
Leishmania donovani Targets Dicer1 to Downregulate miR-122, Lower Serum Cholesterol, and Facilitate Murine Liver Infection.
Infections
Letter to the Editor "Drosha, DGCR8, and Dicer mRNAs are downregulated in human cells infected with dengue virus 4" - Genet. Mol. Res. 15 (2): gmr.15027891 - Drosha, Dicer, and TRBP mRNA are downregulated in Vero cells with the 3'UTR of Dengue virus.
Infections
Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila.
Infections
MicroRNAs Modulate Pathogenesis Resulting from Chlamydial Infection in Mice.
Infections
Monocyte chemoattractant protein-induced protein 1 directly degrades viral miRNAs with a specific motif and inhibits KSHV infection.
Infections
Protective immunity induced by CpG ODNs against white spot syndrome virus (WSSV) via intermediation of virus replication indirectly in Litopenaeus vannamei.
Infections
Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti.
Infections
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Infections
RNA interference directs innate immunity against viruses in adult Drosophila.
Infections
RNA interference-based antiviral immune response against the salivary gland hypertrophy virus in Glossina pallidipes.
Infections
RNA-based immunity terminates viral infection in adult Drosophila in the absence of viral suppression of RNA interference: characterization of viral small interfering RNA populations in wild-type and mutant flies.
Infections
Small interfering RNA pathway contributes to antiviral immunity in Spodoptera frugiperda (Sf9) cells following Autographa californica multiple nucleopolyhedrovirus infection.
Infections
Small RNA Bidirectional Crosstalk During the Interaction Between Wheat and Zymoseptoria tritici.
Infections
Stimuli-dependent cleavage of Dicer during apoptosis.
Infections
Suppression of RNA interference by adenovirus virus-associated RNA.
Infections
Suppression of RNA interference pathway in vitro by Grass carp reovirus.
Infections
Synergistic interactions of begomoviruses with Sweet potato chlorotic stunt virus (genus Crinivirus) in sweet potato (Ipomoea batatas?L.).
Infections
The cII-independent expression of the phage lambda int gene in RNase III-defective E. coli.
Infections
The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection.
Infections
The microRNA pathway is involved in Spodoptera frugiperda (Sf9) cells antiviral immune defense against Autographa californica multiple nucleopolyhedrovirus infection.
Infections
The negative regulation of piscine CD44c in viral and bacterial infection.
Infections
The preferred route for the degradation of silencing target RNAs in transgenic plants depends on pre-established silencing conditions.
Infections
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-? receptor.
Infections
Transcriptomic analysis of Macrobrachium rosenbergii (giant fresh water prawn) post-larvae in response to M. rosenbergii nodavirus (MrNV) infection: de novo assembly and functional annotation.
Infections
Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1.
Infections
Yellow Fever Virus Modulates the Expression of Key Proteins Related to the microRNA Pathway in the Human Hepatocarcinoma Cell Line HepG2.
Infertility
CFTR mutation compromises spermatogenesis by enhancing miR-15b maturation and suppressing its regulatory target CDC25A.
Infertility
Comparative rna-seq analysis of region-specific miRNA expression in the epididymis of cattleyak.
Infertility
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility.
Infertility
Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1.
Infertility
Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects.
Infertility
High-throughput sequencing reveals differential expression of miRNAs in yak and cattleyak epididymis.
Infertility
Involvement of miRNAs and Cell-Secreted Vesicles in Mammalian Ovarian Antral Follicle Development.
Infertility
microRNA 376a Regulates Follicle Assembly by Targeting Pcna in Fetal and Neonatal Mouse Ovaries.
Infertility
MiR-125b Regulates Primordial Follicle Assembly by Targeting Activin Receptor Type 2a in Neonatal Mouse Ovary.
Infertility
Next-generation sequencing analysis reveals segmental patterns of microRNA expression in yak epididymis.
Infertility
Prevention of Chlamydia-induced infertility by inhibition of local caspase activity.
Infertility
Requirement for ERI/DICER Complex in Endogenous RNAi and Sperm Development in Caenorhabditis elegans.
Infertility
Sertoli cell Dicer is essential for spermatogenesis in mice.
Infertility
[Advance on Dicer gene and its role in female reproduction].
Infertility, Female
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility.
Infertility, Female
Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes.
Infertility, Female
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice.
Infertility, Female
Murine follicular development requires oocyte DICER, but not DROSHA.
Infertility, Male
Dicer1 is required for differentiation of the mouse male germline.
Infertility, Male
Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population.
Infertility, Male
Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility.
Infertility, Male
microRNAs in the Testis: Building Up Male Fertility.
Infertility, Male
The role of Dicer1 in the male reproductive tract.
Influenza, Human
Dicer is involved in protection against influenza A virus infection.
Influenza, Human
Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2.
Influenza, Human
Influenza A Virus Expresses High Levels of an Unusual Class of Small Viral Leader RNAs in Infected Cells.
Influenza, Human
Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer.
Influenza, Human
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Influenza, Human
Vero cells as a model to study the effects of adenoviral gene delivery vectors on the RNAi system in context of viral infection.
Insulin Resistance
Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.
Insulin Resistance
Altered pattern of circulating miRNAs in HIV lipodystrophy perturbs key adipose differentiation and inflammation pathways.
Insulin Resistance
Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice.
Insulin Resistance
Recent advances on the role of microRNAs in both insulin resistance and cancer.
Insulin Resistance
Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development.
Insulin Resistance
Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients.
Intellectual Disability
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Intellectual Disability
Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner.
Intellectual Disability
Expression of MicroRNA machinery proteins in different types of chronic rhinosinusitis.
Intellectual Disability
Functional and selective RNA interference in developing axons and growth cones.
Intellectual Disability
The role of PIWI and the miRNA machinery in Drosophila germline determination.
Kidney Failure, Chronic
Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.
Kidney Neoplasms
Structural renal abnormalities in the DICER1 syndrome: a family-based cohort study.
Laryngeal Neoplasms
Association of miRNA biosynthesis genes DROSHA and DGCR8 polymorphisms with cancer susceptibility: a systematic review and meta-analysis.
Laryngeal Neoplasms
Evaluation of polymorphisms in microRNA biosynthesis genes and risk of laryngeal cancer in the Polish population.
Leiomyoma
Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.
Leiomyoma
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Leiomyomatosis
Gynecological lesions in hereditary cancer predisposition syndromes.
Leiomyomatosis
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Leiomyosarcoma
Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.
Leukemia
DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic leukemia.
Leukemia
Dysfunctional niches as a root of hematopoietic malignancy.
Leukemia
Hematologic indices in individuals with pathogenic germline DICER1 variants.
Leukemia
Overexpression of DICER1 induced by the upregulation of GATA1 contributes to the proliferation and apoptosis of leukemia cells.
Leukemia
Stop the dicing in hematopoiesis: What have we learned?
Leukemia, Lymphocytic, Chronic, B-Cell
Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Dicer Gene Expression as a Prognostic Factor in Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia in Fars Province.
Leukemia, Lymphocytic, Chronic, B-Cell
Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Investigation of AID, Dicer, and Drosha Expressions in Patients with Chronic Lymphocytic Leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
MicroRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells.
Leukemia, Myeloid, Acute
Cytoplasmic DROSHA and non-canonical mechanisms of MiR-155 biogenesis in FLT3-ITD acute myeloid leukemia.
Leukemia, Myeloid, Acute
Dicer and outcomes in patients with acute myeloid leukemia (AML).
Leukemia, Myeloid, Acute
DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic leukemia.
Leukemia, Myeloid, Acute
Expression and Clinical Significance of ANXA1 and DICER1 in Myelodysplastic Syndromes.
Leukemia, Myeloid, Acute
Overexpression of DICER1 induced by the upregulation of GATA1 contributes to the proliferation and apoptosis of leukemia cells.
Leukemia-Lymphoma, Adult T-Cell
Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients.
Leydig Cell Tumor
Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features of DICER1 syndrome.
Li-Fraumeni Syndrome
Germline predisposition to genitourinary rhabdomyosarcoma.
Li-Fraumeni Syndrome
Predisposition to pediatric and hematologic cancers: a moving target.
Li-Fraumeni Syndrome
Secondary Sarcomas: Biology, Presentation, and Clinical Care.
Lipodystrophy
Adipose-derived circulating miRNAs regulate gene expression in other tissues.
Lipodystrophy
Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.
Lipodystrophy
Altered pattern of circulating miRNAs in HIV lipodystrophy perturbs key adipose differentiation and inflammation pathways.
Liposarcoma
Deregulation of dicer and mir-155 expression in liposarcoma.
Liver Cirrhosis
MicroRNA-21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis.
Liver Failure
Amino acid-induced regulation of hepatocyte growth: possible role of Drosha.
Liver Neoplasms
MicroRNA-21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis.
Lung Neoplasms
Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.
Lung Neoplasms
Cell- and developmental stage-specific Dicer1 ablation in the lung epithelium models cystic pleuropulmonary blastoma.
Lung Neoplasms
Concordant and Discordant Regulation of Target Genes by miR-31 and Its Isoforms.
Lung Neoplasms
Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer.
Lung Neoplasms
Diagnostic value of plasma expression of microRNAs complementary to Drosha and Dicer in lung cancer patients.
Lung Neoplasms
DICER activates autophagy and promotes cisplatin resistance in non-small cell lung cancer by binding with let-7i-5p.
Lung Neoplasms
DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.
Lung Neoplasms
High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer.
Lung Neoplasms
Impaired microRNA processing enhances cellular transformation and tumorigenesis.
Lung Neoplasms
MicroRNA-128-3p-mediated depletion of Drosha promotes lung cancer cell migration.
Lung Neoplasms
Predictive value of microRNA let-7a expression for efficacy and prognosis of radiotherapy in patients with lung cancer brain metastasis: A case-control study.
Lung Neoplasms
Prognostic value of the MicroRNA regulators Dicer and Drosha in non-small-cell lung cancer: co-expression of Drosha and miR-126 predicts poor survival.
Lung Neoplasms
Reduced expression of Dicer associated with poor prognosis in lung cancer patients.
Lung Neoplasms
rs10719 Polymorphism Located within DROSHA 3'-Untranslated Region is Responsible for Development of Primary Hypertension by Disrupting Binding with microRNA-27b.
Lung Neoplasms
Suppression of Dicer Increases Sensitivity to Gefitinib in Human Lung Cancer Cells.
Lung Neoplasms
The prevalence of germline DICER1 pathogenic variation in cancer populations.
Lung Neoplasms
Usefulness of predictive tests for cancer treatment.
Lyme Disease
RNase III Processing of rRNA in the Lyme Disease Spirochete Borrelia burgdorferi.
Lymphatic Metastasis
Clinicopathological and prognostic significance of the microRNA processing enzyme DICER1 mRNA expression in colorectal cancer patients.
Lymphatic Metastasis
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Lymphatic Metastasis
DROSHA rs10719 T>C is associated with lymph node metastasis and clinical stage of gastric cancer patients.
Lymphatic Metastasis
Dysregulated expression of Dicer in invasive ductal breast carcinoma.
Lymphatic Metastasis
Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances.
Lymphatic Metastasis
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.
Lymphatic Metastasis
The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer.
Lymphatic Metastasis
The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21.
Lymphatic Metastasis
Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma.
Lymphatic Metastasis
[A negative correlation between Drosha expression and gastric adenocarcinoma malignancy and invasion].
Lymphoma
High expression of Dicer reveals a negative prognostic influence in certain subtypes of primary cutaneous T cell lymphomas.
Lymphoma
Hodgkin lymphoma as a novel presentation of familial DICER1 syndrome.
Lymphoma
Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer.
Lymphoma
MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.
Lymphoma
Variation in dicer gene is associated with increased survival in T-cell lymphoma.
Lymphoma, B-Cell
Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab.
Lymphoma, B-Cell
Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer.
Lymphoma, B-Cell
Methods for assembling B-cell lymphoma specific and internalizing aptamer-siRNA nanoparticles via the sticky bridge.
Lymphoma, B-Cell
MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.
Lymphoma, Follicular
MicroRNA profiling of follicular lymphoma identifies microRNAs related to cell proliferation and tumor response.
Lymphoma, Large B-Cell, Diffuse
Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab.
Lymphoma, Non-Hodgkin
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study.
Lymphoma, T-Cell
Variation in dicer gene is associated with increased survival in T-cell lymphoma.
Lymphoma, T-Cell
[Association of microRNA-related genes (DROSHA, DICER1 and GEMIN4) polymorphisms with T-cell lymphoma prognosis].
Lymphoma, T-Cell, Cutaneous
Low Drosha protein expression in cutaneous T-cell lymphoma is associated with worse disease outcome.
Lymphopenia
Survival of Naïve T Cells Requires the Expression of Let-7 miRNAs.
Macular Degeneration
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Macular Degeneration
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.
Macular Degeneration
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation.
Macular Degeneration
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.
Macular Degeneration
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.
Macular Degeneration
ERK1/2 activation is a therapeutic target in age-related macular degeneration.
Macular Degeneration
Histological Characterization of the Dicer1 Mutant Zebrafish Retina.
Macular Degeneration
Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells.
Macular Degeneration
Z-DNA and Z-RNA in human disease.
Malaria
Anopheles gambiae miRNAs as actors of defence reaction against Plasmodium invasion.
Malaria
Characterization of RNA interference in an Anopheles gambiae cell line.
Malaria
Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population.
Malaria, Cerebral
Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population.
Malaria, Cerebral
Polymorphisms in the RNASE3 gene are associated with susceptibility to cerebral malaria in Ghanaian children.
Measles
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Medulloblastoma
Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation.
Medulloblastoma
Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.
Medulloblastoma
MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.
Megalencephaly
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Megalencephaly
Hotspot mutations in DICER1 causing GLOW Syndrome-associated macrocephaly via modulation of specific microRNA populations results in activation of PI3K/ATK/mTOR signaling.
Megalencephaly
Macrocephaly associated with the DICER1 syndrome.
Melanoma
ADAR1p150 regulates the biosynthesis and function of miRNA-149* in human melanoma.
Melanoma
Altered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers.
Melanoma
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.
Melanoma
Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma.
Melanoma
Feed-forward microprocessing and splicing activities at a microRNA-containing intron.
Melanoma
Helicases in Antiviral Immunity: Dual Properties as Sensors and Effectors.
Melanoma
Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi.
Melanoma
Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis.
Melanoma
microRNAs exhibit high frequency genomic alterations in human cancer.
Melanoma
Mutation Scanning of D1705 and D1709 in the RNAse IIIb Domain of MicroRNA Processing Enzyme Dicer in Cutaneous Melanoma.
Melanoma
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.
Melanoma
Reduced expression of nuclear Dicer correlates with melanoma progression.
Melanoma
Sox4-mediated Dicer expression is critical for suppression of melanoma cell invasion.
Melanoma
Stage-specific prognostic biomarkers in melanoma.
Melanoma
The modulation of Dicer regulates tumor immunogenicity in melanoma.
Melanoma
Up-regulated Dicer expression in patients with cutaneous melanoma.
Metabolic Diseases
Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.
Microcephaly
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.
Microcephaly
The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis.
Microphthalmos
Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development.
Monoclonal Gammopathy of Undetermined Significance
Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients.
Mouth Neoplasms
Genetic variations in key microRNA processing genes and risk of head and neck cancer: a case-control study in Chinese population.
Mouth Neoplasms
Identification and characterization of Dicer1e, a Dicer1 protein variant, in oral cancer cells.
Mouth Neoplasms
Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells.
Multiple Endocrine Neoplasia
An update on the genetics of benign pituitary adenomas in children and adolescents.
Multiple Endocrine Neoplasia
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Multiple Endocrine Neoplasia
Predisposition to pediatric and hematologic cancers: a moving target.
Multiple Endocrine Neoplasia
The clinical aspects of pituitary tumour genetics.
Multiple Endocrine Neoplasia Type 1
An update on the genetics of benign pituitary adenomas in children and adolescents.
Multiple Endocrine Neoplasia Type 1
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Multiple Endocrine Neoplasia Type 1
The clinical aspects of pituitary tumour genetics.
Multiple Myeloma
Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells.
Multiple Myeloma
Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients.
Multiple Sclerosis
Decreased Dicer expression is linked to increased expression of co-stimulatory molecule CD80 on B cells in multiple sclerosis.
Multiple Sclerosis
Dicer and microRNA expression in multiple sclerosis and response to interferon therapy.
Multiple Sclerosis
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Multiple Sclerosis
Overexpression of microRNA biogenesis machinery: Drosha, DGCR8 and Dicer in multiple sclerosis patients.
Muscle Neoplasms
Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.
Muscular Atrophy, Spinal
Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Muscular Atrophy, Spinal
Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Muscular Diseases
Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training.
Mycoses
Drosophila Dicer-2 has an RNA interference-independent function that modulates Toll immune signaling.
Mycosis Fungoides
Low Drosha protein expression in cutaneous T-cell lymphoma is associated with worse disease outcome.
Myelodysplastic Syndromes
DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic leukemia.
Myelodysplastic Syndromes
Down-regulation of Dicer1 promotes cellular senescence and decreases the differentiation and stem cell-supporting capacities of mesenchymal stromal cells in patients with myelodysplastic syndrome.
Myelodysplastic Syndromes
Evaluating the Effect of 3'-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction.
Myelodysplastic Syndromes
Expression and Clinical Significance of ANXA1 and DICER1 in Myelodysplastic Syndromes.
Myelodysplastic Syndromes
Hematologic indices in individuals with pathogenic germline DICER1 variants.
Myelodysplastic Syndromes
Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndromes patients.
Myelodysplastic Syndromes
Inflammation-related genes S100s, RNASE3, and CYBB and risk of leukemic transformation in patients with myelodysplastic syndrome with myelofibrosis.
Myocarditis
ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis.
Myotonic Dystrophy
Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets.
Nasal Polyps
Expression of MicroRNA machinery proteins in different types of chronic rhinosinusitis.
Nasopharyngeal Carcinoma
Effects of Dicer1 targeted by EBV-miR-BART6-5p on biological properties and radiosensitivity of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
IKK?-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.
Nasopharyngeal Carcinoma
miR-18a downregulates DICER1 and promotes proliferation and metastasis of nasopharyngeal carcinoma.
Nasopharyngeal Carcinoma
The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma.
Nasopharyngitis
Reduced expression of Dicer11 is associated with poor prognosis in patients with nasopharyngeal carcinoma.
Nematode Infections
RNA interference of an orthologue of Dicer of Meloidogyne incognita alludes to the gene's importance in nematode development.
Neoplasm Metastasis
?-catenin downregulates Dicer to promote ovarian cancer metastasis.
Neoplasm Metastasis
A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
Neoplasm Metastasis
A MicroRNA targeting dicer for metastasis control.
Neoplasm Metastasis
Ago2 promotes tumor metastasis via upregulating FAK expression in hepatocellular carcinoma.
Neoplasm Metastasis
Amplification of Hsa-miR-191/425 Locus Promotes Breast Cancer Proliferation and Metastasis by Targeting DICER1.
Neoplasm Metastasis
Application of microRNA in diagnosis and treatment of ovarian cancer.
Neoplasm Metastasis
Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.
Neoplasm Metastasis
Biallelic Dicer1 loss mediated by aP2-Cre drives angiosarcoma.
Neoplasm Metastasis
Clinicopathological and prognostic significance of the microRNA processing enzyme DICER1 mRNA expression in colorectal cancer patients.
Neoplasm Metastasis
Comprehensive Analysis of MicroRNA (miRNA) Targets in Breast Cancer Cells.
Neoplasm Metastasis
Corrigendum to "Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells" [383 (2016) 282-294].
Neoplasm Metastasis
Crosstalk between NRF2 and Dicer through metastasis regulating MicroRNAs; Mir-34a, Mir-200 family and mir-103/107 family.
Neoplasm Metastasis
Crosstalk between p53 and TGF-? Signalling.
Neoplasm Metastasis
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Neoplasm Metastasis
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Neoplasm Metastasis
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Neoplasm Metastasis
Dicer reprograms stromal fibroblasts to a pro-inflammatory and tumor-promoting phenotype in ovarian cancer.
Neoplasm Metastasis
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Neoplasm Metastasis
Down-regulation of Dicer expression in cervical cancer tissues.
Neoplasm Metastasis
Down-regulation of Dicer in hepatocellular carcinoma.
Neoplasm Metastasis
Down-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancer.
Neoplasm Metastasis
DROSHA rs10719 T>C is associated with lymph node metastasis and clinical stage of gastric cancer patients.
Neoplasm Metastasis
Dual mechanism of DICER downregulation facilitates cancer metastasis.
Neoplasm Metastasis
Dysregulated expression of Dicer in invasive ductal breast carcinoma.
Neoplasm Metastasis
Effects of Dicer1 targeted by EBV-miR-BART6-5p on biological properties and radiosensitivity of nasopharyngeal carcinoma.
Neoplasm Metastasis
Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis.
Neoplasm Metastasis
Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells.
Neoplasm Metastasis
HIF-1? promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
Neoplasm Metastasis
Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner.
Neoplasm Metastasis
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Neoplasm Metastasis
Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances.
Neoplasm Metastasis
Impaired DICER1 function promotes stemness and metastasis in colon cancer.
Neoplasm Metastasis
Impaired expression of Drosha in breast cancer.
Neoplasm Metastasis
In vivo modeling of metastatic human high-grade serous ovarian cancer in mice.
Neoplasm Metastasis
Metastasis suppression: a role of the Dice(r).
Neoplasm Metastasis
Metastasis: It's nicer with DICER.
Neoplasm Metastasis
MicroRNA-107, an Oncogene MicroRNA that Regulates Tumor Invasion and Metastasis By Targeting DICER1 in Gastric Cancer: MiR-107 promotes gastric cancer invasion and metastasis.
Neoplasm Metastasis
MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma.
Neoplasm Metastasis
miR-122 Promotes Metastasis of Clear-Cell Renal Cell Carcinoma by Downregulating Dicer.
Neoplasm Metastasis
miR-18a downregulates DICER1 and promotes proliferation and metastasis of nasopharyngeal carcinoma.
Neoplasm Metastasis
Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing.
Neoplasm Metastasis
Mutation Scanning of D1705 and D1709 in the RNAse IIIb Domain of MicroRNA Processing Enzyme Dicer in Cutaneous Melanoma.
Neoplasm Metastasis
NKp46-mediated Dicer1 inactivation results in defective NK-cell differentiation and effector functions in mice.
Neoplasm Metastasis
Oncogene dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma.
Neoplasm Metastasis
Predictive value of microRNA let-7a expression for efficacy and prognosis of radiotherapy in patients with lung cancer brain metastasis: A case-control study.
Neoplasm Metastasis
Prognostic significance of Dicer expression in hepatocellular carcinoma.
Neoplasm Metastasis
Prognostic significance of low DICER expression regulated by miR-130a in cervical cancer.
Neoplasm Metastasis
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
Neoplasm Metastasis
Reduced expression of Dicer11 is associated with poor prognosis in patients with nasopharyngeal carcinoma.
Neoplasm Metastasis
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
Neoplasm Metastasis
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.
Neoplasm Metastasis
The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
Neoplasm Metastasis
The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer.
Neoplasm Metastasis
The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21.
Neoplasm Metastasis
Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma.
Neoplasm Metastasis
[A negative correlation between Drosha expression and gastric adenocarcinoma malignancy and invasion].
Neoplasm, Residual
Predictive factors for the sensitivity of radiotherapy and prognosis of esophageal squamous cell carcinoma.
Neoplasms
A case of neuroblastoma in DICER1 syndrome: Chance finding or noncanonical causation?
Neoplasms
A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.
Neoplasms
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Neoplasms
A Cystic Renal Mass in the Setting of a Pneumothorax: More Than Meets the Eye?
Neoplasms
A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
Neoplasms
A family with Sertoli-Leydig cell tumour, multinodular goiter, and DICER1 mutation.
Neoplasms
A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype.
Neoplasms
A Japanese Family with DICER1 Syndrome Found in Childhood-Onset Multinodular Goitre.
Neoplasms
A low dicer expression is associated with resistance to 5-FU-based chemoradiotherapy and a shorter overall survival in patients with oral squamous cell carcinoma.
Neoplasms
A MicroRNA targeting dicer for metastasis control.
Neoplasms
A novel DICER1 mutation identified in a female with ovarian Sertoli-Leydig cell tumor and multinodular goiter: a case report.
Neoplasms
A pair of DICER1-positive monozygotic twins: One with pleuropulmonary blastoma, another with acute transient hepatitis.
Neoplasms
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes.
Neoplasms
A Positive Feedback Loop Between DICER1 and Differentiation Transcription Factors Is Important for Thyroid Tumorigenesis.
Neoplasms
A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.
Neoplasms
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Neoplasms
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.
Neoplasms
Aberrant splicing in B-cell acute lymphoblastic leukemia.
Neoplasms
Ablation of Dicer leads to widespread perturbation of signaling pathways.
Neoplasms
Absence of DICER1, CTCF, RPL22, DNMT3A, TRRAP, IDH1 and IDH2 hotspot mutations in patients with various subtypes of ovarian carcinomas.
Neoplasms
Absence of mature microRNAs inactivates the response of gene expression to carcinogenesis induced by N-ethyl-N-nitrosourea in mouse liver.
Neoplasms
ADAR and Immune Silencing in Cancer.
Neoplasms
Ago2 promotes tumor metastasis via upregulating FAK expression in hepatocellular carcinoma.
Neoplasms
Alterations in miRNA processing and expression in pleomorphic adenomas of the salivary gland.
Neoplasms
Altered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers.
Neoplasms
Altered microRNA processing proteins in HPV-induced cancers.
Neoplasms
An autopsy case of prostatic rhabdomyosarcoma with DICER1 hotspot mutation.
Neoplasms
An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors.
Neoplasms
An NF90/NF110-mediated feedback amplification loop regulates dicer expression and controls ovarian carcinoma progression.
Neoplasms
An Unusual Enteric Yolk Sac Tumor: First Report of an Ovarian Germ Cell Tumor Associated With a Germline Pathogenic Variant in DICER1.
Neoplasms
An update on the central nervous system manifestations of DICER1 syndrome.
Neoplasms
An update on the genetics of benign pituitary adenomas in children and adolescents.
Neoplasms
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma.
Neoplasms
Anaplastic Sarcoma of the Kidney With Heterologous Ganglioneuroblastic Differentiation: Another DICER1-Associated Tumor.
Neoplasms
Anaplastic sarcomas of the kidney are characterized by DICER1 mutations.
Neoplasms
Androgen-Secreting Ovarian Tumors.
Neoplasms
Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.
Neoplasms
Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma.
Neoplasms
Association between genetic variants in DICER1 and cancer risk: An updated meta-analysis.
Neoplasms
Association between the DICER rs1057035 polymorphism and cancer risk: evidence from a meta-analysis of 1,2675 individuals.
Neoplasms
Association of miRNA biosynthesis genes DROSHA and DGCR8 polymorphisms with cancer susceptibility: a systematic review and meta-analysis.
Neoplasms
ATRX driver mutation in a composite malignant pheochromocytoma.
Neoplasms
Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P.
Neoplasms
Being Small and Intronic: miRNAs That Count!
Neoplasms
Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma.
Neoplasms
Biallelic DICER1 mutations occur in Wilms tumours.
Neoplasms
Biallelic Dicer1 loss mediated by aP2-Cre drives angiosarcoma.
Neoplasms
BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex.
Neoplasms
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.
Neoplasms
Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis.
Neoplasms
Case report: an identical twin with Sertoli-Leydig cell tumor.
Neoplasms
Characterization of a naturally occurring truncated Dicer.
Neoplasms
Childhood Rhabdomyosarcoma of the Female Genital Tract: Association with Pathogenic DICER1 Variation, Clinicopathological Features, and Outcomes.
Neoplasms
Chromosomal anomalies at 1q, 3, 16q, and mutations of SIX1 and DROSHA genes underlie Wilms tumor recurrences.
Neoplasms
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma.
Neoplasms
Clinical and Molecular Characteristics May Alter Treatment Strategies of Thyroid Malignancies in DICER1-syndrome.
Neoplasms
Clinical Characteristics and Mutation Analyses of Ovarian Sertoli-Leydig Cell Tumors.
Neoplasms
Clinical Outcomes and Complications of Pituitary Blastoma.
Neoplasms
Clinical relevance of screening checklists for detecting cancer predisposition syndromes in Asian childhood tumours.
Neoplasms
Clinicians Practicing Obstetrics and Gynecology Are Uniquely Situated to Recognize DICER1 Syndrome.
Neoplasms
Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer.
Neoplasms
Clinicopathological and prognostic significance of the microRNA processing enzyme DICER1 mRNA expression in colorectal cancer patients.
Neoplasms
Common genetic polymorphisms of microRNA biogenesis pathway genes and risk of breast cancer: a case-control study in Korea.
Neoplasms
Comprehensive Analysis of MicroRNA (miRNA) Targets in Breast Cancer Cells.
Neoplasms
Consensus recommendations from the EXPeRT/PARTNER groups for the diagnosis and therapy of sex cord stromal tumors in children and adolescents.
Neoplasms
Crosstalk between p53 and TGF-? Signalling.
Neoplasms
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Neoplasms
CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma.
Neoplasms
Cytomorphologic features of thyroid disease in patients with DICER1 mutations: A report of cytology-histopathology correlation in 7 patients.
Neoplasms
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Neoplasms
Deciphering the Key Features of Malignant Tumor Microenvironment for Anti-cancer Therapy.
Neoplasms
Decreased expression of DICER1 in gastric cancer.
Neoplasms
Deep sequencing reveals spatially distributed distinct hotspot mutations in DICER1-related multinodular goiter.
Neoplasms
Deregulation of dicer and mir-155 expression in liposarcoma.
Neoplasms
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
Neoplasms
Detection of the DICER1 hotspot mutation alongside immunohistochemical analysis may provide a better diagnostic measure for ovarian Sertoli-Leydig cell tumors.
Neoplasms
Development of a metastatic fluorescent Lewis Lung carcinoma mouse model: identification of mRNAs and microRNAs involved in tumor invasion.
Neoplasms
Development of Novel Genetically Engineered Adenoviruses Based on Functional Analyses of Adenovirus-encoded Small RNAs.
Neoplasms
Diagnostic and Prognostic Potential of MicroRNA Maturation Regulators Drosha, AGO1 and AGO2 in Urothelial Carcinomas of the Bladder.
Neoplasms
Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells.
Neoplasms
Dicer affects cisplatin?mediated apoptosis in epithelial ovarian cancer cells.
Neoplasms
Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients.
Neoplasms
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Neoplasms
Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice.
Neoplasms
Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL.
Neoplasms
Dicer expression and microRNA dysregulation associate with aggressive features in thyroid cancer.
Neoplasms
Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison.
Neoplasms
Dicer Gene Expression as a Prognostic Factor in Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia in Fars Province.
Neoplasms
DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma.
Neoplasms
Dicer in action at replication-transcription collisions.
Neoplasms
Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.
Neoplasms
Dicer Knockdown Inhibits Endothelial Cell Tumor Growth via MicroRNA 21a-3p Targeting of Nox-4.
Neoplasms
Dicer promotes tumorigenesis by translocating to nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
Neoplasms
Dicer regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1.
Neoplasms
Dicer reprograms stromal fibroblasts to a pro-inflammatory and tumor-promoting phenotype in ovarian cancer.
Neoplasms
Dicer suppresses cytoskeleton remodeling and tumorigenesis of colorectal epithelium by miR-324-5p mediated suppression of HMGXB3 and WASF-2.
Neoplasms
Dicer suppresses MMP-2-mediated invasion and VEGFA-induced angiogenesis and serves as a promising prognostic biomarker in human clear cell renal cell carcinoma.
Neoplasms
Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2?.
Neoplasms
Dicer, Drosha, and outcomes in patients with ovarian cancer.
Neoplasms
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.
Neoplasms
Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1.
Neoplasms
DICER1 and FOXL2 Mutation Status Correlates With Clinicopathologic Features in Ovarian Sertoli-Leydig Cell Tumors.
Neoplasms
DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.
Neoplasms
Dicer1 dysfunction promotes stemness and aggression in endometrial carcinoma.
Neoplasms
DICER1 exons 25 and 26 mutations are rare in common human tumours besides Sertoli-Leydig cell tumour.
Neoplasms
DICER1 expression and outcomes in endometrioid endometrial adenocarcinoma.
Neoplasms
Dicer1 functions as a haploinsufficient tumor suppressor.
Neoplasms
DICER1 hot-spot mutations in ovarian gynandroblastoma.
Neoplasms
DICER1 hotspot mutations in non-epithelial gonadal tumours.
Neoplasms
DICER1 hotspot mutations in ovarian Sertoli-Leydig cell tumors: a potential association with androgenic effects.
Neoplasms
DICER1 Hotspot Mutations in Pleuropulmonary Blastoma: A Case Series From a Tertiary Center.
Neoplasms
Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21-mediated tumor suppressor Pdcd4 repression.
Neoplasms
DICER1 mutation and pituitary prolactinoma
Neoplasms
DICER1 mutation and tumors associated with a familial tumor predisposition syndrome: practical considerations.
Neoplasms
DICER1 Mutation Detected in an Infant Guides Accurate Diagnosis of Auto-Amputated Embryonal Rhabdomyosarcoma.
Neoplasms
DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.
Neoplasms
DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.
Neoplasms
DICER1 mutations are frequent in adolescent-onset papillary thyroid carcinoma.
Neoplasms
DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation.
Neoplasms
DICER1 mutations in a patient with an ovarian Sertoli-Leydig tumor, well-differentiated fetal adenocarcinoma of the lung, and familial multinodular goiter.
Neoplasms
DICER1 Mutations in embryonal rhabdomyosarcomas from children with and without familial PPB-tumor predisposition syndrome.
Neoplasms
DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors.
Neoplasms
DICER1 mutations in familial pleuropulmonary blastoma.
Neoplasms
DICER1 Mutations in the Era of Expanding Integrative Clinical Sequencing in Pediatric Oncology.
Neoplasms
Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination.
Neoplasms
DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know.
Neoplasms
Dicer1 Promotes Colon Cancer Cell Invasion and Migration Through Modulation of tRF-20-MEJB5Y13 Expression Under Hypoxia.
Neoplasms
DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours.
Neoplasms
DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1-associated sarcoma.
Neoplasms
DICER1 somatic mutations strongly impair miRNA processing even in benign thyroid lesions.
Neoplasms
DICER1 Syndrome and Cancer Predisposition: From a Rare Pediatric Tumor to Lifetime Risk.
Neoplasms
DICER1 syndrome can mimic different genetic tumor predispositions.
Neoplasms
DICER1 Syndrome.
Neoplasms
DICER1 syndrome: a new cancer syndrome.
Neoplasms
DICER1 syndrome: Approach to testing and management at a large pediatric tertiary care center.
Neoplasms
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome.
Neoplasms
DICER1 Syndrome: DICER1 Mutations in Rare Cancers.
Neoplasms
DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.
Neoplasms
DICER1-associated central nervous system sarcoma in children: comprehensive clinicopathologic and genetic analysis of a newly described rare tumor.
Neoplasms
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Neoplasms
DICER1-associated metastatic abdominopelvic primitive neuroectodermal tumor with an EWSR1 rearrangement in a 16-yr-old female.
Neoplasms
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Neoplasms
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Neoplasms
DICER1-Related Embryonal Rhabdomyosarcoma of the Uterine Corpus in a Prepubertal Girl.
Neoplasms
DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry.
Neoplasms
DICER1: mutations, microRNAs and mechanisms.
Neoplasms
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Neoplasms
Differential Expression of Dicer, miRNAs, and Inflammatory Markers in Diabetic Ins2+/- Akita Hearts.
Neoplasms
Disruption of Dicer1 Induces Dysregulated Fetal Gene Expression and Promotes Hepatocarcinogenesis.
Neoplasms
Disruption of microRNA Biogenesis Confers Resistance to ER Stress-Induced Cell Death Upstream of the Mitochondrion.
Neoplasms
Distinct DICER1 Hotspot Mutations Identify Bilateral Tumors as Separate Events.
Neoplasms
DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker.
Neoplasms
DNA nanoclew templated spherical nucleic acids for siRNA delivery.
Neoplasms
Docosahexaenoic Acid Modulates the Enterocyte Caco-2 Cell Expression of MicroRNAs Involved in Lipid Metabolism.
Neoplasms
Down-regulation of Dicer expression in cervical cancer tissues.
Neoplasms
Down-regulation of dicer expression in ovarian cancer tissues.
Neoplasms
Down-regulation of Dicer in hepatocellular carcinoma.
Neoplasms
Down-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancer.
Neoplasms
Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer.
Neoplasms
Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia.
Neoplasms
Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab.
Neoplasms
Downregulation of Dicer enhances tumor cell proliferation and invasion.
Neoplasms
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.
Neoplasms
DROSHA rs10719 T>C is associated with lymph node metastasis and clinical stage of gastric cancer patients.
Neoplasms
Drosha-independent miR-6778-5p strengthens gastric cancer stem cell stemness via regulation of cytosolic one-carbon folate metabolism.
Neoplasms
Dual mechanism of DICER downregulation facilitates cancer metastasis.
Neoplasms
Dysregulated expression of Dicer in invasive ductal breast carcinoma.
Neoplasms
Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53 on Drosha complex activity.
Neoplasms
Dysregulation of microRNA biosynthesis enzyme Dicer plays an important role in gastric cancer progression.
Neoplasms
Dysregulation of the miRNA biogenesis components DICER1, DROSHA, DGCR8 and AGO2 in clear cell renal cell carcinoma in both a Korean cohort and the cancer genome atlas kidney clear cell carcinoma cohort.
Neoplasms
E2F1-regulated DROSHA promotes miR-630 biosynthesis in cisplatin-exposed cancer cells.
Neoplasms
Effect of estrogen-related receptor silencing on miRNA protein machinery expression, global methylation, and deacetylation in bank vole (Myodes glareolus) and mouse tumor Leydig cells.
Neoplasms
Effects of Dicer1 targeted by EBV-miR-BART6-5p on biological properties and radiosensitivity of nasopharyngeal carcinoma.
Neoplasms
EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.
Neoplasms
Embryonal rhabdomyosarcoma in a patient with a heterozygous frameshift variant in the DICER1 gene and additional manifestations of the DICER1 syndrome.
Neoplasms
Embryonal Rhabdomyosarcoma of the Ovary and Fallopian Tube: Rare Neoplasms Associated With Germline and Somatic DICER1 Mutations.
Neoplasms
Embryonal rhabdomyosarcoma of the uterine corpus: a clinicopathological and molecular analysis of 21 cases highlighting a frequent association with DICER1 mutations.
Neoplasms
EpCAM Aptamer-mediated Survivin Silencing Sensitized Cancer Stem Cells to Doxorubicin in a Breast Cancer Model.
Neoplasms
Epigenetics-related genes in prostate cancer: expression profile in prostate cancer tissues, androgen-sensitive and -insensitive cell lines.
Neoplasms
Epithelial inactivation of Yy1 abrogates lung branching morphogenesis.
Neoplasms
ERK-mediated transcriptional activation of Dicer is involved in gemcitabine resistance of pancreatic cancer.
Neoplasms
Erratum: Publisher Correction: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.
Neoplasms
Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.
Neoplasms
ETMR: a tumor entity in its infancy.
Neoplasms
Evaluation of molecular analysis in challenging ovarian sex cord-stromal tumours: a review of 50 cases.
Neoplasms
Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells.
Neoplasms
Evolution of Renal Cysts to Anaplastic Sarcoma of Kidney in a Child With DICER1 Syndrome.
Neoplasms
Exogenous expression of miRNA-3613-3p causes APAF1 downregulation and affects several proteins involved in apoptosis in BE(2)-C human neuroblastoma cells.
Neoplasms
Exosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer.
Neoplasms
Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome.
Neoplasms
Expanding the spectrum of dicer1-associated sarcomas.
Neoplasms
Exploring the association between DICER1 mutations and differentiated thyroid carcinoma.
Neoplasms
Exploring the endocrine manifestations of DICER1 mutations.
Neoplasms
Expression levels of microRNA machinery components Drosha, Dicer and DGCR8 in human (AGS, HepG2, and KEYSE-30) cancer cell lines.
Neoplasms
Expression Levels of the microRNA Processing Enzymes Drosha and Dicer in Epithelial Skin Cancer.
Neoplasms
Expression of Dicer and Drosha in triple-negative breast cancer.
Neoplasms
Expression of Dicer and Its Related MiRNAs in the Progression of Prostate Cancer.
Neoplasms
Expression of the microRNA regulators Drosha, Dicer and Ago2 in non-small cell lung carcinomas.
Neoplasms
Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas.
Neoplasms
Extending the phenotypes associated with DICER1 mutations.
Neoplasms
Extensive post-transcriptional regulation of microRNAs and its implications for cancer.
Neoplasms
Familial multinodular goiter and Sertoli-Leydig cell tumors associated with a large intragenic in-frame
Neoplasms
Familial pleuropulmonary blastoma in Australia.
Neoplasms
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study.
Neoplasms
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression.
Neoplasms
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours.
Neoplasms
Gemcitabine exhibits a suppressive effect on pancreatic cancer cell growth by regulating processing of PVT1 to miR1207.
Neoplasms
Gene of the month: DICER1: ruler and controller.
Neoplasms
Genetic Causes of Rare Pediatric Ovarian Tumors.
Neoplasms
Genetic changes in nonepithelial ovarian cancer.
Neoplasms
Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer.
Neoplasms
Genetics and genomics of ovarian sex cord-stromal tumors.
Neoplasms
Genomics of a pediatric ovarian fibrosarcoma. Association with the DICER1 syndrome.
Neoplasms
Germ-line and somatic DICER1 mutations in pineoblastoma.
Neoplasms
Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides.
Neoplasms
Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
Neoplasms
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Neoplasms
Germline and Somatic DICER1 Mutations in a Well-Differentiated Fetal Adenocarcinoma of the Lung.
Neoplasms
Germline and somatic DICER1 mutations in familial and sporadic liver tumors.
Neoplasms
Germline Genetics and Childhood Cancer: Emerging Cancer Predisposition Syndromes and Psychosocial Impacts.
Neoplasms
Germline mutations of DICER1 in Chinese women with BRCA1/BRCA2-negative familial breast cancer.
Neoplasms
Global microRNA depletion suppresses tumor angiogenesis.
Neoplasms
Gynecologic and reproductive health in patients with pathogenic germline variants in DICER1.
Neoplasms
Gynecologic Manifestations of the DICER1 Syndrome.
Neoplasms
Gynecological lesions in hereditary cancer predisposition syndromes.
Neoplasms
Hematologic indices in individuals with pathogenic germline DICER1 variants.
Neoplasms
Hereditary ovarian tumour syndromes: current update on genetics and imaging.
Neoplasms
Hereditary Renal Cystic Disorders: Imaging of the Kidneys and Beyond.
Neoplasms
HIF-1? promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
Neoplasms
High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer.
Neoplasms
High Prevalence of DICER1 Mutations and Low Frequency of Gene Fusions in Pediatric Follicular-Patterned Tumors of the Thyroid.
Neoplasms
High-grade Müllerian Adenosarcoma: Genomic and Clinicopathologic Characterization of a Distinct Neoplasm With Prevalent TP53 Pathway Alterations and Aggressive Behavior.
Neoplasms
High-sensitivity sequencing reveals multi-organ somatic mosaicism causing DICER1 syndrome.
Neoplasms
Hodgkin lymphoma as a novel presentation of familial DICER1 syndrome.
Neoplasms
Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1? and epithelial-mesenchymal transition.
Neoplasms
Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.
Neoplasms
Hypoxia-induced Nur77 activates PI3K/Akt signaling via suppression of Dicer/let-7i-5p to induce epithelial-to-mesenchymal transition.
Neoplasms
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.
Neoplasms
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Neoplasms
Identification of Familial Hodgkin Lymphoma Predisposing Genes Using Whole Genome Sequencing.
Neoplasms
Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour.
Neoplasms
Identification of Homozygous Somatic DICER1 Mutation in Pleuropulmonary Blastoma.
Neoplasms
Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree.
Neoplasms
Identification of two 14q32 deletions involving DICER1 associated with the development of DICER1-related tumors.
Neoplasms
IKK?-mediated biogenesis of miR-196a through interaction with Drosha regulates the sensitivity of cancer cells to radiotherapy.
Neoplasms
Imaging of DICER1 syndrome.
Neoplasms
Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.
Neoplasms
Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi.
Neoplasms
Impaired DICER1 function promotes stemness and metastasis in colon cancer.
Neoplasms
Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients.
Neoplasms
Impaired expression of Drosha in breast cancer.
Neoplasms
Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness.
Neoplasms
Impaired microRNA processing enhances cellular transformation and tumorigenesis.
Neoplasms
In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs.
Neoplasms
Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer.
Neoplasms
Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo.
Neoplasms
Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions.
Neoplasms
Interplay between steroid signalling and microRNAs: implications for hormone-dependent cancers.
Neoplasms
Intrathyroidal Thymus (Incidentaloma) Mimicking Thyroid Neoplasia in DICER1 Syndrome.
Neoplasms
Involvement of microRNA in AU-rich element-mediated mRNA instability.
Neoplasms
Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4A(DCAF1) to promote colon cancer development.
Neoplasms
Judicious DICER1 testing and surveillance imaging facilitates early diagnosis and cure of pleuropulmonary blastoma.
Neoplasms
Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin.
Neoplasms
Lack of mutation of DICER1 and FOXL2 genes in microcystic stromal tumor of the ovary.
Neoplasms
Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors.
Neoplasms
let-7 regulates Dicer expression and constitutes a negative feedback loop.
Neoplasms
Letter to the editor: Does Dicer Expression Affect shRNA processing?
Neoplasms
Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer.
Neoplasms
Long noncoding RNA LINC00899 suppresses breast cancer progression by inhibiting miR-425.
Neoplasms
Loss of Dicer expression is associated with breast cancer progression and recurrence.
Neoplasms
Loss of H3K27me3 and nuclear expression of TLE1 in primary intracranial sarcoma, DICER1-mutant.
Neoplasms
Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.
Neoplasms
Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma.
Neoplasms
Low Drosha protein expression in cutaneous T-cell lymphoma is associated with worse disease outcome.
Neoplasms
Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level.
Neoplasms
Macrocephaly associated with the DICER1 syndrome.
Neoplasms
Macrofollicular variant follicular thyroid tumors are DICER1 mutated and exhibit distinct histological features.
Neoplasms
Macrofollicular Variant of Follicular Thyroid Carcinoma (MV-FTC) with a Somatic DICER1 Gene Mutation: Case Report and Review of the Literature.
Neoplasms
Macrofollicular Variant of Follicular Thyroid Carcinoma: A Rare Underappreciated Pitfall in the Diagnosis of Thyroid Carcinoma.
Neoplasms
Major clinical research advances in gynecologic cancer in 2012.
Neoplasms
Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer.
Neoplasms
Malignant teratoid tumor of the thyroid gland: an aggressive primitive multiphenotypic malignancy showing organotypical elements and frequent DICER1 alterations-is the term "thyroblastoma" more appropriate?
Neoplasms
Malignant teratomas of the thyroid gland: clinico-radiologic and cytomorphologic features of a rare entity.
Neoplasms
MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.
Neoplasms
MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.
Neoplasms
Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
Neoplasms
Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report.
Neoplasms
Metachronous Type I pleuropulmonary blastoma and atypical choroid plexus papilloma in a young child.
Neoplasms
Metformin shows anti-inflammatory effects in murine macrophages through Dicer/microribonucleic acid-34a-5p and microribonucleic acid-125b-5p.
Neoplasms
Methods for assembling B-cell lymphoma specific and internalizing aptamer-siRNA nanoparticles via the sticky bridge.
Neoplasms
MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.
Neoplasms
MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.
Neoplasms
MicroRNA biogenesis takes another single hit from microsatellite instability.
Neoplasms
MicroRNA biogenesis: dicing assay.
Neoplasms
MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy.
Neoplasms
MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype.
Neoplasms
microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma.
Neoplasms
MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN.
Neoplasms
MicroRNA-107, an Oncogene MicroRNA that Regulates Tumor Invasion and Metastasis By Targeting DICER1 in Gastric Cancer: MiR-107 promotes gastric cancer invasion and metastasis.
Neoplasms
MicroRNA-128-3p-mediated depletion of Drosha promotes lung cancer cell migration.
Neoplasms
MicroRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells.
Neoplasms
MicroRNA-143 is a putative predictive factor for the response to fluoropyrimidine-based chemotherapy in patients with metastatic colorectal cancer.
Neoplasms
microRNA-18a, a member of the oncogenic miR-17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells.
Neoplasms
MicroRNA-221 governs tumor suppressor HDAC6 to potentiate malignant progression of liver cancer.
Neoplasms
MicroRNAs and cancer: past, present, and potential future.
Neoplasms
MicroRNAs Link Estrogen Receptor Alpha Status and Dicer Levels in Breast Cancer.
Neoplasms
MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells.
Neoplasms
miR-126 in human cancers: clinical roles and current perspectives.
Neoplasms
miR-130b is an EMT-related microRNA that targets DICER1 for aggression in endometrial cancer.
Neoplasms
MiR-590-5p, a density-sensitive microRNA, inhibits tumorigenesis by targeting YAP1 in colorectal cancer.
Neoplasms
miRNA processing and human cancer: DICER1 cuts the mustard.
Neoplasms
MiRNA-103/107 in Primary High-Grade Serous Ovarian Cancer and Its Clinical Significance.
Neoplasms
Mixed Epithelial and Stromal Tumor of the Kidney: Mutation Analysis of the DICER 1 Gene in 29 Cases.
Neoplasms
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.
Neoplasms
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.
Neoplasms
Monitoring Dicer-Mediated miRNA-21 Maturation and Ago2 Loading by a Dual-Colour FIT PNA Probe Set.
Neoplasms
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Neoplasms
Mucoepidermoid carcinoma of upper aerodigestive tract: clinicopathologic study of 78 cases with immunohistochemical analysis of Dicer expression.
Neoplasms
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Neoplasms
Multinodular goitre is a gateway for molecular testing of DICER1 syndrome.
Neoplasms
Multiple DICER1-related tumors in a child with a large interstitial 14q32 deletion.
Neoplasms
Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing.
Neoplasms
Mutation analysis of DICER1 gene in hematologic tumors.
Neoplasms
Mutation Scanning of D1705 and D1709 in the RNAse IIIb Domain of MicroRNA Processing Enzyme Dicer in Cutaneous Melanoma.
Neoplasms
Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors.
Neoplasms
Mutiple DICER1-related lesions associated with a germline deep intronic mutation.
Neoplasms
Nasal Chondromesenchymal Hamartoma (NCMH): a systematic review of the literature with a new case report.
Neoplasms
Nasal chondromesenchymal hamartomas arise secondary to germline and somatic mutations of DICER1 in the pleuropulmonary blastoma tumor predisposition disorder.
Neoplasms
Nasal chondromesenchymal hamartomas in a cohort with pathogenic germline variation in DICER1.
Neoplasms
NCAM1/FGF module serves as a putative pleuropulmonary blastoma therapeutic target.
Neoplasms
Neoplasm Risk Among Individuals With a Pathogenic Germline Variant in DICER1.
Neoplasms
New roles for Dicer in the nucleolus and its relevance to cancer.
Neoplasms
New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma.
Neoplasms
Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismodegib therapy: an integrative molecular and surgical case study.
Neoplasms
Novel DICER1 mutation as cause of multinodular goiter in children.
Neoplasms
Novel intronic DICER1 variation associated with pleuropulmonary blastoma in two siblings.
Neoplasms
Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.
Neoplasms
NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake.
Neoplasms
Nuclear Drosha enhances cell invasion via an EGFR-ERK1/2-MMP7 signaling pathway induced by dysregulated miRNA-622/197 and their targets LAMC2 and CD82 in gastric cancer.
Neoplasms
Oncogene dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma.
Neoplasms
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Neoplasms
Oncogenic MicroRNAs Biogenesis as a Drug Target: Structure-Activity Relationship Studies on New Aminoglycoside Conjugates.
Neoplasms
Outcome of two pairs of monozygotic twins with pleuropulmonary blastoma: case report.
Neoplasms
Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome.
Neoplasms
Ovarian Sertoli-Leydig Cell Tumor with Elevated Inhibin B as a Cause of Secondary Amenorrhea in an Adolescent with Germ Line DICER1 Mutation.
Neoplasms
Ovarian Sertoli-Leydig Cell Tumor, Multinodular Goiter, Cystic Nephromas and DICER1 Mutations: Case Report and Literature Review.
Neoplasms
Ovarian sex cord-stromal tumors in patients with probable or confirmed germline DICER1 mutations.
Neoplasms
Ovarian sex cord-stromal tumors, pleuropulmonary blastoma and DICER1 mutations: A report from the International Pleuropulmonary Blastoma Registry.
Neoplasms
Ovarian Sex Cord-Stromal Tumors.
Neoplasms
Ovarian sex cord-stromal tumours: an update in recent molecular advances.
Neoplasms
Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry.
Neoplasms
Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells.
Neoplasms
Overexpression of Dicer predicts poor survival in colorectal cancer.
Neoplasms
Overexpression of DICER1 induced by the upregulation of GATA1 contributes to the proliferation and apoptosis of leukemia cells.
Neoplasms
Paired comparisons of mutational profiles before and after brachytherapy in asian uveal melanoma patients.
Neoplasms
Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma.
Neoplasms
Pediatric imaging in DICER1 syndrome.
Neoplasms
Pediatric Renal Tumors: Updates in the Molecular Era.
Neoplasms
Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins.
Neoplasms
Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study.
Neoplasms
Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations.
Neoplasms
Pleuropulmonary blastoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations.
Neoplasms
Pleuropulmonary Blastoma in Pediatric Lung Lesions.
Neoplasms
Pleuropulmonary blastoma-like peritoneal sarcoma: a newly described malignancy associated with biallelic DICER1 pathogenic variation.
Neoplasms
Pleuropulmonary Blastoma: A Single-center Case Series of 6 Patients.
Neoplasms
Pleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome.
Neoplasms
Pleuropulmonary Blastoma: More Than a Lung Neoplasm of Childhood.
Neoplasms
Poorly differentiated thyroid carcinoma of childhood and adolescence: a distinct entity characterized by DICER1 mutations.
Neoplasms
Potentially functional genetic variants in microRNA processing genes and risk of HBV-related hepatocellular carcinoma.
Neoplasms
Practical roles for molecular diagnostic testing in ovarian adult granulosa cell tumour, Sertoli-Leydig cell tumour, microcystic stromal tumour and their mimics.
Neoplasms
Predictive factors for the sensitivity of radiotherapy and prognosis of esophageal squamous cell carcinoma.
Neoplasms
Predisposition to pediatric and hematologic cancers: a moving target.
Neoplasms
Predominant DICER1 Pathogenic Variants in Pediatric Follicular Thyroid Carcinomas.
Neoplasms
Presacral malignant teratoid neoplasm in association with pathogenic DICER1 variation.
Neoplasms
Primary Biphasic Hepatic Sarcoma in DICER1 Syndrome.
Neoplasms
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
Neoplasms
Primary Lung Tumors in Children: Radiologic-Pathologic Correlation From the Radiologic Pathology Archives.
Neoplasms
Primary uterine ectomesenchymoma harboring a DICER1 mutation: case report with molecular analysis.
Neoplasms
Prognostic significance of deregulated dicer expression in breast cancer.
Neoplasms
Prognostic significance of Dicer cellular levels in soft tissue sarcomas.
Neoplasms
Prognostic significance of Dicer expression in hepatocellular carcinoma.
Neoplasms
Prognostic significance of Dicer expression in ovarian cancer-link to global microRNA changes and oestrogen receptor expression.
Neoplasms
Prognostic significance of low DICER expression regulated by miR-130a in cervical cancer.
Neoplasms
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
Neoplasms
Programmed Death Ligand 1 Expression and Related Markers in Pleuropulmonary Blastoma.
Neoplasms
Proliferation and tumorigenesis of a murine sarcoma cell line in the absence of DICER1.
Neoplasms
Proteomic identification of target proteins following Drosha knockdown in cervical cancer.
Neoplasms
Psychological stress enhances tumor growth and diminishes radiation response in preclinical model of lung cancer.
Neoplasms
Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma.
Neoplasms
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Neoplasms
Quantification of thyroid cancer and multinodular goiter risk in the DICER1 syndrome: a family-based cohort study.
Neoplasms
Racial Differences in Expression Levels of miRNA Machinery-Related Genes, Dicer, Drosha, DGCR8, and AGO2, in Asian Korean Papillary Thyroid Carcinoma and Comparative Validation Using the Cancer Genome Atlas.
Neoplasms
Radiographic screening of infants and young children with genetic predisposition for rare malignancies: DICER1 mutations and pleuropulmonary blastoma.
Neoplasms
Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors.
Neoplasms
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.
Neoplasms
Rare Germline DICER1 Variants in Pediatric Patients With Cushing's Disease: What Is Their Role?
Neoplasms
Recent advances in Wilms tumor predisposition.
Neoplasms
Recent advances on the role of microRNAs in both insulin resistance and cancer.
Neoplasms
Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors.
Neoplasms
Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis.
Neoplasms
Recurrent DICER1 Hotspot Mutations in Malignant Thyroid Gland Teratomas: Molecular Characterization and Proposal for a Separate Classification.
Neoplasms
Recurrent gynandroblastoma of the ovary with germline DICER1 mutation: A case report and review of the literature.
Neoplasms
Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma.
Neoplasms
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.
Neoplasms
Reduced DICER1 Elicits an Interferon Response in Endometrial Cancer Cells.
Neoplasms
Reduced expression of Dicer associated with poor prognosis in lung cancer patients.
Neoplasms
Regulatory RNAs: future perspectives in diagnosis, prognosis, and individualized therapy.
Neoplasms
Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer.
Neoplasms
Rescuing dicer defects via inhibition of an anti-dicing nuclease.
Neoplasms
Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis.
Neoplasms
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Neoplasms
Restoration of miRNA-149 Expression by TmPyP4 Induced Unfolding of Quadruplex within Its Precursor.
Neoplasms
Retraction: A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function.
Neoplasms
Retraction: Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL.
Neoplasms
Rewiring macrophages for anti-tumour immunity.
Neoplasms
Role of components of microRNA machinery in carcinogenesis.
Neoplasms
Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis.
Neoplasms
Role of Dicer in regulating oxaliplatin resistance of colon cancer cells.
Neoplasms
Role of Dicer1 in thyroid cell proliferation and differentiation.
Neoplasms
Role of miRNAs in tumor and endothelial cell interactions during tumor progression.
Neoplasms
Rolling the dice to discover the role of DICER in tumorigenesis.
Neoplasms
Second primary rhabdomyosarcoma of the uterine cervix presenting with synchronous ovarian Sertoli-Leydig cell tumor: An illustrative case of DICER1 syndrome.
Neoplasms
Sensitively distinguishing intracellular precursor and mature microRNA abundance.
Neoplasms
Sertoli-Leydig cell tumor in two siblings with DICER1 syndrome: A case report and literature review.
Neoplasms
Sertoli-Leydig cell tumor, thyroid follicular carcinoma and rhabdomyosarcoma of the uterine cervix in a prepubertal girl with pathogenic germline variant in DICER1 gene.
Neoplasms
Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature.
Neoplasms
Serum Exosomal Dicer Is a Useful Biomarker for Early Detection of Differentiated Gastric Adenocarcinoma.
Neoplasms
Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma.
Neoplasms
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.
Neoplasms
Significantly greater prevalence of DICER1 alterations in uterine embryonal rhabdomyosarcoma compared to adenosarcoma.
Neoplasms
Silencing Dicer expression enhances cellular proliferative and invasive capacities in human tongue squamous cell carcinoma.
Neoplasms
Sjogren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.
Neoplasms
Somatic DICER1 gene mutation in sporadic intraocular medulloepithelioma without pleuropulmonary blastoma syndrome.
Neoplasms
Somatic DICER1 Mutations in a Pubertal Girl with Cervical Embryonal Rhabdomyosarcoma and Papillary Thyroid Adenoma.
Neoplasms
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.
Neoplasms
Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.
Neoplasms
Somatic tumour testing establishes that bilateral DICER1-associated ovarian Sertoli-Leydig cell tumours represent independent primary neoplasms.
Neoplasms
Sox4-mediated Dicer expression is critical for suppression of melanoma cell invasion.
Neoplasms
Spectrum of DICER1 Germline Pathogenic Variants in Ovarian Sertoli-Leydig Cell Tumor.
Neoplasms
Successful Management of a Patient with Malignant Thyroid Teratoma.
Neoplasms
Suppression of collagen synthesis by Dicer gene silencing in hepatic stellate cells.
Neoplasms
Suppression of Dicer Increases Sensitivity to Gefitinib in Human Lung Cancer Cells.
Neoplasms
Suppression of microRNA activity amplifies IFN-?-induced macrophage activation and promotes anti-tumour immunity.
Neoplasms
Surveillance recommendations for DICER1 pathogenic variant carriers: a report from the SIOPE Host Genome Working Group and CanGene-CanVar Clinical Guideline Working Group.
Neoplasms
Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation.
Neoplasms
Systematic evaluation of the miRNA-ome and its downstream effects on mRNA expression identifies gastric cancer progression.
Neoplasms
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
Neoplasms
Temporal order of RNase IIIb and loss-of-function mutations during development determines phenotype in DICER1 syndrome: a unique variant of the two-hit tumor suppression model.
Neoplasms
Ten years of DICER1 mutations: Provenance, distribution, and associated phenotypes.
Neoplasms
Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features of DICER1 syndrome.
Neoplasms
THE "-OMAS" and "-OPIAS": Targeted and Philosophical Considerations Regarding Hamartomas, Choristomas, Teratomas, Ectopias, and Heterotopias in Pediatric Otorhinolaryngologic Pathology.
Neoplasms
The antileukemia activity of natural product HQ17(3) is possibly associated with downregulation of miR-17-92 cluster.
Neoplasms
The clinical aspects of pituitary tumour genetics.
Neoplasms
The co-occurrence of an ovarian Sertoli-Leydig cell tumor with a thyroid carcinoma is highly suggestive of a DICER1 syndrome.
Neoplasms
The development of Wilms tumor: from WT1 and microRNA to animal models.
Neoplasms
The epigenetic regulation of Dicer and microRNA biogenesis by Panobinostat.
Neoplasms
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.
Neoplasms
The impact of variations in transcription of DICER and AGO2 on exacerbation of childhood B-cell lineage acute lymphoblastic leukaemia.
Neoplasms
The insertion in the double-stranded RNA binding domain of human Drosha is important for its function.
Neoplasms
The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
Neoplasms
The modulation of Dicer regulates tumor immunogenicity in melanoma.
Neoplasms
The molecular landscape of ETMR at diagnosis and relapse.
Neoplasms
The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma-differences in histological subtypes.
Neoplasms
The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors.
Neoplasms
The paradox of dicer in cancer.
Neoplasms
The prevalence of DICER1 pathogenic variation in population databases.
Neoplasms
The prevalence of germline DICER1 pathogenic variation in cancer populations.
Neoplasms
The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer.
Neoplasms
The regulatory roles of miRNA and methylation on oncogene and tumor suppressor gene expression in pancreatic cancer cells.
Neoplasms
The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21.
Neoplasms
The role of FOXL2, SOX9, and ?-catenin expression and DICER1 mutation in differentiating sex cord tumor with annular tubules from other sex cord tumors of the ovary.
Neoplasms
The role of RNA editing enzyme ADAR1 in human disease.
Neoplasms
The Value of DICER1 Mutation Analysis in "Subtle" Diagnostically Challenging Embryonal Rhabdomyosarcomas of the Uterine Cervix.
Neoplasms
Thoracic Sertoli-Leydig cell tumor: An alternative type of pleuropulmonary blastoma associated with DICER1 variation.
Neoplasms
Three synchronous malignancies in a patient with DICER1 syndrome.
Neoplasms
Transcript Level of MicroRNA Processing Elements in Gastric Cancer.
Neoplasms
Tumor Progression in DICER1-mutated Cystic Nephroma - witnessing the genesis of Anaplastic Sarcoma of the Kidney.
Neoplasms
Type II pleuropulmonary blastoma in a 3-years-old female with dyspnea: a case report and review of literature.
Neoplasms
Ultrasensitive electrochemical detection of Dicer1 3'UTR for the fast analysis of alternative cleavage and polyadenylation.
Neoplasms
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Neoplasms
Unique Haploinsufficient Role of the MicroRNA-Processing Molecule Dicer1 in a Murine Colitis-Associated Tumorigenesis Model.
Neoplasms
Unusual phenotypes in patients with a pathogenic germline variant in DICER1.
Neoplasms
Up-regulated Dicer expression in patients with cutaneous melanoma.
Neoplasms
Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma.
Neoplasms
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma.
Neoplasms
Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients.
Neoplasms
Using Pan RNA-Seq Analysis to Reveal the Ubiquitous Existence of 5' and 3' End Small RNAs.
Neoplasms
Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.
Neoplasms
Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT): A Morphologic and Molecular Study of 26 Cases Confirms Recurrent NCOA1-3 Rearrangement.
Neoplasms
Variation in dicer gene is associated with increased survival in T-cell lymphoma.
Neoplasms
Whole Genome Analysis of Ovarian Granulosa Cell Tumors Reveals Tumor Heterogeneity and a High-Grade TP53-Specific Subgroup.
Neoplasms
Wilms Tumor Suppressor, WT1, Cooperates with MicroRNA-26a and MicroRNA-101 to Suppress Translation of the Polycomb Protein, EZH2, in Mesenchymal Stem Cells.
Neoplasms
Wilms tumor, pleuropulmonary blastoma, and DICER1: case report and literature review.
Neoplasms
[A family with a congenital DICER1 mutation].
Neoplasms
[A negative correlation between Drosha expression and gastric adenocarcinoma malignancy and invasion].
Neoplasms
[Application of molecular analysis in differential diagnosis of ovarian adult granulosa cell tumors].
Neoplasms
[Cystic nephroma in a 15-month-old boy with DICER1 mutation].
Neoplasms
[Dicer efficiently converts large dsRNAs into siRNAs suitable for COX-2 gene]
Neoplasms
[DICER1 mutated, solid/trabecular thyroid papillary carcinoma in an 11-year-old child].
Neoplasms
[Effect of estrogen or progesterone combined with paclitaxel on human ovarian cancer cell growth and Drosha expression].
Neoplasms
[Hereditary predispositions to follicular thyroid tumors].
Neoplasms
[MiRNA regulatory mechanism in tumor initiation and progression].
Neoplasms
[Ovarian Sertoli-Leydig cell tumors: DICER1 hotspot mutations and associated clinicopathological features].
Neoplasms
[Progress in studies on the relationship between ?Dicer and ovarian tumor].
Neoplasms
[The pathology of hereditary ovarian tumors].
Neoplasms
[Virilizing ovarian tumor: the challenges of differential diagnosis].
Neoplasms, Germ Cell and Embryonal
An Unusual Enteric Yolk Sac Tumor: First Report of an Ovarian Germ Cell Tumor Associated With a Germline Pathogenic Variant in DICER1.
Neoplasms, Germ Cell and Embryonal
DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours.
Neoplasms, Germ Cell and Embryonal
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome.
Neoplasms, Germ Cell and Embryonal
Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
Neoplasms, Germ Cell and Embryonal
Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors.
Nephroma, Mesoblastic
Pediatric Renal Tumors: Updates in the Molecular Era.
Nephrotic Syndrome
Dicer and Drosha expression in patients with nephrotic syndrome.
Nervous System Diseases
Astrocytic miR-324-5p is essential for synaptic formation by suppressing the secretion of CCL5 from astrocytes.
Nervous System Diseases
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.
Neuroblastoma
A case of neuroblastoma in DICER1 syndrome: Chance finding or noncanonical causation?
Neuroblastoma
A child with neuroblastoma and metachronous anaplastic sarcoma of the kidney: Underlying DICER1 syndrome?
Neuroblastoma
A novel splice variant of the human dicer gene is expressed in neuroblastoma cells.
Neuroblastoma
Characterization of a naturally occurring truncated Dicer.
Neuroblastoma
Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.
Neuroblastoma
Exogenous expression of miRNA-3613-3p causes APAF1 downregulation and affects several proteins involved in apoptosis in BE(2)-C human neuroblastoma cells.
Neuroblastoma
Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma.
Neuroblastoma
microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma.
Neuroblastoma
MiR-192 directly binds and regulates Dicer1 expression in neuroblastoma.
Neuroblastoma
Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis.
Neurodegenerative Diseases
Cerebellar neurodegeneration in the absence of microRNAs.
Neurodegenerative Diseases
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.
Neuroectodermal Tumors, Primitive
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome.
Neuroectodermal Tumors, Primitive
DICER1-associated metastatic abdominopelvic primitive neuroectodermal tumor with an EWSR1 rearrangement in a 16-yr-old female.
Neuroectodermal Tumors, Primitive
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Neuroectodermal Tumors, Primitive
Embryonal rhabdomyosarcoma in a patient with a heterozygous frameshift variant in the DICER1 gene and additional manifestations of the DICER1 syndrome.
Neuroectodermal Tumors, Primitive
Extending the phenotypes associated with DICER1 mutations.
Neuroectodermal Tumors, Primitive
Eye Tumors in Childhood as First Sign of Tumor Predisposition Syndromes: Insights from an Observational Study Conducted in Germany and Austria.
Neuroectodermal Tumors, Primitive
Imaging of DICER1 syndrome.
Neuroectodermal Tumors, Primitive
Intraocular medulloepithelioma - A review of clinical features, DICER 1 mutation, and management.
Neuroectodermal Tumors, Primitive
Medulloepithelioma in DICER1 syndrome treated with resection.
Neuroectodermal Tumors, Primitive
Multiple DICER1-related tumors in a child with a large interstitial 14q32 deletion.
Neuroectodermal Tumors, Primitive
Pleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome.
Neuroectodermal Tumors, Primitive
Somatic DICER1 gene mutation in sporadic intraocular medulloepithelioma without pleuropulmonary blastoma syndrome.
Neuroectodermal Tumors, Primitive
Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.
Neuroectodermal Tumors, Primitive
Successful Management of a Patient with Malignant Thyroid Teratoma.
Neurofibromatoses
An update on the genetics of benign pituitary adenomas in children and adolescents.
Neurofibromatoses
Genetic and Epigenetic Causes of Pituitary Adenomas.
Neurofibromatoses
Germline predisposition to genitourinary rhabdomyosarcoma.
Neurofibromatoses
Novel Genetic Causes of Pituitary Adenomas.
Neurofibromatoses
Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1.
Neurofibromatoses
Secondary Sarcomas: Biology, Presentation, and Clinical Care.
Neurofibromatosis 1
An update on the genetics of benign pituitary adenomas in children and adolescents.
Neurofibromatosis 1
Genetic and Epigenetic Causes of Pituitary Adenomas.
Neurofibromatosis 1
Germline predisposition to genitourinary rhabdomyosarcoma.
Neurofibromatosis 1
Novel Genetic Causes of Pituitary Adenomas.
Neurofibromatosis 1
Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1.
Neurofibromatosis 1
Secondary Sarcomas: Biology, Presentation, and Clinical Care.
Neurofibrosarcoma
Common genetic variants in the microRNA biogenesis pathway are associated with malignant peripheral nerve sheath tumor risk in a Chinese population.
Neuroinflammatory Diseases
JNK-mediated microglial DICER degradation potentiates inflammatory responses to induce dopaminergic neuron loss.
Nevus, Pigmented
Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi.
Noonan Syndrome
Germline predisposition to genitourinary rhabdomyosarcoma.
Obesity
A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice.
Obesity
Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity.
Obesity
Hypothalamic miR-103 protects from hyperphagic obesity in mice.
Obesity
Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients.
Osteoarthritis
Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.
Osteosarcoma
Human osteoblasts are resistant to Apo2L/TRAIL-mediated apoptosis.
Ovarian Neoplasms
?-catenin downregulates Dicer to promote ovarian cancer metastasis.
Ovarian Neoplasms
Application of microRNA in diagnosis and treatment of ovarian cancer.
Ovarian Neoplasms
Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P.
Ovarian Neoplasms
Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage.
Ovarian Neoplasms
Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression.
Ovarian Neoplasms
Dicer affects cisplatin?mediated apoptosis in epithelial ovarian cancer cells.
Ovarian Neoplasms
Dicer and Drosha in ovarian cancer.
Ovarian Neoplasms
Dicer reprograms stromal fibroblasts to a pro-inflammatory and tumor-promoting phenotype in ovarian cancer.
Ovarian Neoplasms
Dicer, Drosha, and outcomes in patients with ovarian cancer.
Ovarian Neoplasms
DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours.
Ovarian Neoplasms
Down-regulation of dicer expression in ovarian cancer tissues.
Ovarian Neoplasms
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Ovarian Neoplasms
Major clinical research advances in gynecologic cancer in 2012.
Ovarian Neoplasms
microRNAs exhibit high frequency genomic alterations in human cancer.
Ovarian Neoplasms
MiRNA-103/107 in Primary High-Grade Serous Ovarian Cancer and Its Clinical Significance.
Ovarian Neoplasms
Overexpression of Dicer predicts poor survival in colorectal cancer.
Ovarian Neoplasms
Potential role of miR-9 and miR-223 in recurrent ovarian cancer.
Ovarian Neoplasms
Prognostic significance of Dicer expression in ovarian cancer-link to global microRNA changes and oestrogen receptor expression.
Ovarian Neoplasms
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.
Ovarian Neoplasms
Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer.
Ovarian Neoplasms
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Ovarian Neoplasms
Role of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis.
Ovarian Neoplasms
Sertoli-Leydig cell tumor in two siblings with DICER1 syndrome: A case report and literature review.
Ovarian Neoplasms
Somatic tumour testing establishes that bilateral DICER1-associated ovarian Sertoli-Leydig cell tumours represent independent primary neoplasms.
Ovarian Neoplasms
[Effect of estrogen or progesterone combined with paclitaxel on human ovarian cancer cell growth and Drosha expression].
Pancreatic Neoplasms
Dicer regulates differentiation and viability during mouse pancreatic cancer initiation.
Pancreatic Neoplasms
ERK-mediated transcriptional activation of Dicer is involved in gemcitabine resistance of pancreatic cancer.
Papilloma
Revisiting pleuropulmonary blastoma and atypical choroid plexus papilloma in a young child: DICER1 syndrome or not?
Papilloma, Choroid Plexus
Revisiting pleuropulmonary blastoma and atypical choroid plexus papilloma in a young child: DICER1 syndrome or not?
Paraganglioma
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Paraganglioma
Predisposition to pediatric and hematologic cancers: a moving target.
Paralysis
Israeli acute paralysis virus associated paralysis symptoms, viral tissue distribution and Dicer-2 induction in bumblebee workers (Bombus terrestris).
Paralysis
The deletion of dicer in mature myelinating glial cells causes progressive axonal degeneration but not overt demyelination in adult mice.
Paraproteinemias
Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients.
Parasitic Diseases
Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.
Parkinson Disease
A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA.
Parkinson Disease
Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin.
Parkinson Disease
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Parkinson Disease
Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson's disease.
Perivascular Epithelioid Cell Neoplasms
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Persistent Infection
Potentially functional genetic variants in microRNA processing genes and risk of HBV-related hepatocellular carcinoma.
Peutz-Jeghers Syndrome
Genetics and genomics of ovarian sex cord-stromal tumors.
Peutz-Jeghers Syndrome
Gynecological lesions in hereditary cancer predisposition syndromes.
Peutz-Jeghers Syndrome
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Peutz-Jeghers Syndrome
[The pathology of hereditary ovarian tumors].
Pilomatrixoma
DICER1 syndrome can mimic different genetic tumor predispositions.
Pinealoma
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Pinealoma
Germ-line and somatic DICER1 mutations in pineoblastoma.
Pinealoma
Germline DICER1 mutation and associated loss of heterozygosity in a pineoblastoma.
Pinealoma
Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome.
Pinealoma
Loss of H3K27me3 and nuclear expression of TLE1 in primary intracranial sarcoma, DICER1-mutant.
Pinealoma
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.
Pinealoma
Pediatric imaging in DICER1 syndrome.
Pinealoma
Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8.
Pinealoma
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Pinealoma
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.
Pinealoma
Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma.
Pituitary ACTH Hypersecretion
Germline and somatic DICER1 mutations in a pituitary blastoma causing infantile-onset Cushing's disease.
Pituitary ACTH Hypersecretion
Rare Germline DICER1 Variants in Pediatric Patients With Cushing's Disease: What Is Their Role?
Pituitary Diseases
DICER1 mutation and pituitary prolactinoma
Pituitary Neoplasms
An update on the genetics of benign pituitary adenomas in children and adolescents.
Pituitary Neoplasms
Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects.
Pituitary Neoplasms
Insights into pituitary tumorigenesis: from Sanger sequencing to next-generation sequencing and beyond.
Pituitary Neoplasms
Novel Genetic Causes of Pituitary Adenomas.
Pituitary Neoplasms
Pituitary tumours in MEN1 syndrome - the new insight into the diagnosis and treatment.
Pituitary Neoplasms
Rare Germline DICER1 Variants in Pediatric Patients With Cushing's Disease: What Is Their Role?
Pituitary Neoplasms
The clinical aspects of pituitary tumour genetics.
Pituitary Neoplasms
UPDATE ON THE CLINICOPATHOLOGY OF PITUITARY ADENOMAS.
Pneumonia
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.
Pneumothorax
Diagnosis and Treatment of Pleuropulmonary Blastoma in Children: A Single-Center Report of 41 Cases.
Polycystic Kidney Diseases
MicroRNAs regulate renal tubule maturation through modulation of Pkd1.
Polycystic Ovary Syndrome
MicroRNA-9119 regulates cell viability of granulosa cells in polycystic ovarian syndrome via mediating Dicer expression.
Polycystic Ovary Syndrome
Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients.
Polymyositis
Comparative sequence analysis of ribonucleases HII, III, II PH and D.
Pre-Eclampsia
Relationships between Dicer 1 polymorphism and expression levels in the etiopathogenesis of preeclampsia.
Pre-Eclampsia
The Drosha rs10719 T>C polymorphism is associated with preeclampsia susceptibility.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Dicer Gene Expression as a Prognostic Factor in Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia in Fars Province.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Evaluation of the clinical significance of RNase III enzyme DROSHA in pediatrics acute lymphocytic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Influence of variants of the drosha, mir499a, and mir938 genes on susceptibility to acute lymphoblastic leukemia in an admixed population from the brazilian amazon.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21-mediated tumor suppressor Pdcd4 repression.
Primary Myelofibrosis
Inflammation-related genes S100s, RNASE3, and CYBB and risk of leukemic transformation in patients with myelodysplastic syndrome with myelofibrosis.
Primary Ovarian Insufficiency
Association of polymorphisms in microRNA machinery genes (DROSHA, DICER1, RAN, and XPO5) with risk of idiopathic primary ovarian insufficiency in Korean women.
Primary Ovarian Insufficiency
Murine follicular development requires oocyte DICER, but not DROSHA.
Prolactinoma
DICER1 mutation and pituitary prolactinoma
Prostatic Intraepithelial Neoplasia
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma.
Prostatic Neoplasms
A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis.
Prostatic Neoplasms
Down-regulation of Dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer.
Prostatic Neoplasms
Expression of Dicer and Its Related MiRNAs in the Progression of Prostate Cancer.
Prostatic Neoplasms
Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.
Prostatic Neoplasms
Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer.
Prostatic Neoplasms
MicroRNAs Are Mediators of Androgen Action in Prostate and Muscle.
Prostatic Neoplasms
Proteomics analyses of prostate cancer cells reveal cellular pathways associated with androgen resistance.
Prostatic Neoplasms
Syndecan-1 up-regulates microRNA-331-3p and mediates epithelial-to-mesenchymal transition in prostate cancer.
Proteinuria
MicroRNAs and their role in progressive kidney diseases.
Proteinuria
MiRNA expression profile and miRNA-mRNA integrated analysis (MMIA) during podocyte differentiation.
Proteinuria
Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.
Proteinuria
Review: The role of microRNAs in kidney disease.
Proteinuria
Selective dicer suppression in the kidney alters GSK3?/?-catenin pathways promoting a glomerulocystic disease.
Psoriasis
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Psoriasis
Overexpression of Drosha, DiGeorge syndrome critical region gene 8 (DGCR8), and Dicer mRNAs in the pathogenesis of psoriasis.
Pulmonary Blastoma
Somatic DICER1 mutations in adult-onset pulmonary blastoma.
Pulmonary Disease, Chronic Obstructive
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes.
Pulmonary Embolism
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine platelets.
Pulmonary Fibrosis
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.
Rectal Neoplasms
Dicer and miRNA in relation to clinicopathological variables in colorectal cancer patients.
Renal Insufficiency
Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT).
Renal Insufficiency
Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation.
Renal Insufficiency
Selective dicer suppression in the kidney alters GSK3?/?-catenin pathways promoting a glomerulocystic disease.
Reperfusion Injury
Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury.
Retinal Degeneration
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.
Retinal Degeneration
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.
Retinal Neovascularization
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.
Retinoblastoma
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Retinoblastoma
Secondary Sarcomas: Biology, Presentation, and Clinical Care.
Retinoblastoma
Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation.
Rhabdoid Tumor
Gynecological lesions in hereditary cancer predisposition syndromes.
Rhabdoid Tumor
Hereditary ovarian tumour syndromes: current update on genetics and imaging.
Rhabdoid Tumor
Pediatric Renal Tumors: Updates in the Molecular Era.
Rhabdoid Tumor
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Rhabdomyosarcoma
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Rhabdomyosarcoma
An autopsy case of prostatic rhabdomyosarcoma with DICER1 hotspot mutation.
Rhabdomyosarcoma
Childhood Rhabdomyosarcoma of the Female Genital Tract: Association with Pathogenic DICER1 Variation, Clinicopathological Features, and Outcomes.
Rhabdomyosarcoma
DICER1 mutations are frequent in müllerian adenosarcomas and are independent of rhabdomyosarcomatous differentiation.
Rhabdomyosarcoma
Embryonic cervical rhabdomyosarcoma complicated with uterine inversion with cerebral venous sinus thrombosis as the first symptom: a case report and literature review.
Rhabdomyosarcoma
Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree.
Rhabdomyosarcoma
Second primary rhabdomyosarcoma of the uterine cervix presenting with synchronous ovarian Sertoli-Leydig cell tumor: An illustrative case of DICER1 syndrome.
Rhabdomyosarcoma
Sertoli-Leydig cell tumor, thyroid follicular carcinoma and rhabdomyosarcoma of the uterine cervix in a prepubertal girl with pathogenic germline variant in DICER1 gene.
Rhabdomyosarcoma
Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a "spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant".
Rhabdomyosarcoma, Embryonal
Adult-Onset Cervical Embryonal Rhabdomyosarcoma and DICER1 Mutations.
Rhabdomyosarcoma, Embryonal
An Unusual Enteric Yolk Sac Tumor: First Report of an Ovarian Germ Cell Tumor Associated With a Germline Pathogenic Variant in DICER1.
Rhabdomyosarcoma, Embryonal
Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.
Rhabdomyosarcoma, Embryonal
DICER1 Mutation Detected in an Infant Guides Accurate Diagnosis of Auto-Amputated Embryonal Rhabdomyosarcoma.
Rhabdomyosarcoma, Embryonal
DICER1 mutation-positive Giant Botryoid Fibroepithelial polyp of the urinary bladder mimicking embryonal rhabdomyosarcoma.
Rhabdomyosarcoma, Embryonal
DICER1 mutations in an adolescent with cervical embryonal rhabdomyosarcoma (cERMS).
Rhabdomyosarcoma, Embryonal
DICER1 Mutations in embryonal rhabdomyosarcomas from children with and without familial PPB-tumor predisposition syndrome.
Rhabdomyosarcoma, Embryonal
DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know.
Rhabdomyosarcoma, Embryonal
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Rhabdomyosarcoma, Embryonal
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Rhabdomyosarcoma, Embryonal
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Rhabdomyosarcoma, Embryonal
Embryonal rhabdomyosarcoma in a patient with a heterozygous frameshift variant in the DICER1 gene and additional manifestations of the DICER1 syndrome.
Rhabdomyosarcoma, Embryonal
Embryonal Rhabdomyosarcoma of the Ovary and Fallopian Tube: Rare Neoplasms Associated With Germline and Somatic DICER1 Mutations.
Rhabdomyosarcoma, Embryonal
Embryonal rhabdomyosarcoma of the uterine corpus: a clinicopathological and molecular analysis of 21 cases highlighting a frequent association with DICER1 mutations.
Rhabdomyosarcoma, Embryonal
Expanding the spectrum of dicer1-associated sarcomas.
Rhabdomyosarcoma, Embryonal
Extending the phenotypes associated with DICER1 mutations.
Rhabdomyosarcoma, Embryonal
Gynecologic and reproductive health in patients with pathogenic germline variants in DICER1.
Rhabdomyosarcoma, Embryonal
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Rhabdomyosarcoma, Embryonal
Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome.
Rhabdomyosarcoma, Embryonal
Pediatric imaging in DICER1 syndrome.
Rhabdomyosarcoma, Embryonal
Pleuropulmonary blastoma-like peritoneal sarcoma: a newly described malignancy associated with biallelic DICER1 pathogenic variation.
Rhabdomyosarcoma, Embryonal
Pleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome.
Rhabdomyosarcoma, Embryonal
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
Rhabdomyosarcoma, Embryonal
Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma.
Rhabdomyosarcoma, Embryonal
Significantly greater prevalence of DICER1 alterations in uterine embryonal rhabdomyosarcoma compared to adenosarcoma.
Rhabdomyosarcoma, Embryonal
Somatic DICER1 Mutations in a Pubertal Girl with Cervical Embryonal Rhabdomyosarcoma and Papillary Thyroid Adenoma.
Rhabdomyosarcoma, Embryonal
The Value of DICER1 Mutation Analysis in "Subtle" Diagnostically Challenging Embryonal Rhabdomyosarcomas of the Uterine Cervix.
Rhabdomyosarcoma, Embryonal
Unusual phenotypes in patients with a pathogenic germline variant in DICER1.
Rheumatic Diseases
The RNA interference pathway: a new target for autoimmunity.
Rhinitis, Allergic
Identification of polymorphisms in the RNase3 gene and the association with allergic rhinitis.
ribonuclease iii deficiency
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases.
ribonuclease iii deficiency
Abnormal Expression of DICER1 Leads to Dysregulation of Inflammatory Effectors in Human Synoviocytes.
ribonuclease iii deficiency
An emerging role of Alu RNA in geographic atrophy pathogenesis: the implication for novel therapeutic strategies.
ribonuclease iii deficiency
Calvarial bone development and suture closure in Dicer-deficient mice.
ribonuclease iii deficiency
Canonical and alternate functions of the microRNA biogenesis machinery.
ribonuclease iii deficiency
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
ribonuclease iii deficiency
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.
ribonuclease iii deficiency
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage.
ribonuclease iii deficiency
Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain.
ribonuclease iii deficiency
Dicer deficiency in proximal tubules exacerbates renal injury and tubulointerstitial fibrosis and upregulates Smad2/3.
ribonuclease iii deficiency
Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex.
ribonuclease iii deficiency
Dicer1 Deficiency in the IPF Fibroblastic Focus Promotes Fibrosis by Suppressing MicroRNA Biogenesis.
ribonuclease iii deficiency
Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21-mediated tumor suppressor Pdcd4 repression.
ribonuclease iii deficiency
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation.
ribonuclease iii deficiency
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.
ribonuclease iii deficiency
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
ribonuclease iii deficiency
Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis.
ribonuclease iii deficiency
Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis.
ribonuclease iii deficiency
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.
ribonuclease iii deficiency
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis.
ribonuclease iii deficiency
Endo-siRNA deficiency results in oocyte maturation failure and apoptosis in porcine oocytes.
ribonuclease iii deficiency
Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4.
ribonuclease iii deficiency
Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.
ribonuclease iii deficiency
Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice.
ribonuclease iii deficiency
Gene of the month: DICER1: ruler and controller.
ribonuclease iii deficiency
Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals.
ribonuclease iii deficiency
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression.
ribonuclease iii deficiency
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice.
ribonuclease iii deficiency
Meiotic maturation failure induced by DICER1 deficiency is derived from primary oocyte ooplasm.
ribonuclease iii deficiency
Mesenchymal cell differentiation and diseases: involvement of translin/TRAX complexes and associated proteins.
ribonuclease iii deficiency
MicroRNA-Deficient NK Cells Exhibit Decreased Survival but Enhanced Function.
ribonuclease iii deficiency
MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice.
ribonuclease iii deficiency
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption.
ribonuclease iii deficiency
Rescuing dicer defects via inhibition of an anti-dicing nuclease.
ribonuclease iii deficiency
Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients.
ribonuclease iii deficiency
Suppression of microRNA activity amplifies IFN-?-induced macrophage activation and promotes anti-tumour immunity.
ribonuclease iii deficiency
Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation.
ribonuclease iii deficiency
THYROCYTE-SPECIFIC DICER1 DEFICIENCY ALTERS THYROID FOLLICULAR ORGANIZATION AND PREVENTS GOITER DEVELOPMENT.
ribonuclease iii deficiency
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy.
RNA Virus Infections
Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs.
RNA Virus Infections
Small RNAs tackle large viruses: RNA interference-based antiviral defense against DNA viruses in insects.
RNA Virus Infections
The evolving world of small RNAs from RNA viruses.
Sarcoidosis
Expression of DROSHA and DICER genes in peripheral blood leukocytes in lung sarcoidosis.
Sarcoma
A child with neuroblastoma and metachronous anaplastic sarcoma of the kidney: Underlying DICER1 syndrome?
Sarcoma
Anaplastic sarcomas of the kidney are characterized by DICER1 mutations.
Sarcoma
DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma.
Sarcoma
DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1-associated sarcoma.
Sarcoma
DICER1 Syndrome and Cancer Predisposition: From a Rare Pediatric Tumor to Lifetime Risk.
Sarcoma
DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
Sarcoma
DICER1-associated metastatic abdominopelvic primitive neuroectodermal tumor with an EWSR1 rearrangement in a 16-yr-old female.
Sarcoma
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Sarcoma
Embryonal rhabdomyosarcoma in a patient with a heterozygous frameshift variant in the DICER1 gene and additional manifestations of the DICER1 syndrome.
Sarcoma
Evolution of Renal Cysts to Anaplastic Sarcoma of Kidney in a Child With DICER1 Syndrome.
Sarcoma
Expanding the spectrum of dicer1-associated sarcomas.
Sarcoma
Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma.
Sarcoma
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study.
Sarcoma
Imaging of DICER1 syndrome.
Sarcoma
Metachronous anaplastic sarcoma of the kidney and thyroid follicular carcinoma as manifestations of DICER1 abnormalities.
Sarcoma
MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma.
Sarcoma
Multiple DICER1-related tumors in a child with a large interstitial 14q32 deletion.
Sarcoma
Nasal chondromesenchymal hamartomas arise secondary to germline and somatic mutations of DICER1 in the pleuropulmonary blastoma tumor predisposition disorder.
Sarcoma
Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry.
Sarcoma
Pediatric Renal Tumors: Updates in the Molecular Era.
Sarcoma
Pleuropulmonary blastoma-like peritoneal sarcoma: a newly described malignancy associated with biallelic DICER1 pathogenic variation.
Sarcoma
Primary Biphasic Hepatic Sarcoma in DICER1 Syndrome.
Sarcoma
Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1.
Sarcoma
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
Sarcoma
Prognostic significance of Dicer cellular levels in soft tissue sarcomas.
Sarcoma
Proliferation and tumorigenesis of a murine sarcoma cell line in the absence of DICER1.
Sarcoma
Sarcoma and germ-line DICER1 mutations - Authors' reply.
Sarcoma
Sarcoma and germ-line DICER1 mutations.
Sarcoma
Secondary Sarcomas: Biology, Presentation, and Clinical Care.
Sarcoma
Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma.
Sarcoma
Tumor Progression in DICER1-mutated Cystic Nephroma - witnessing the genesis of Anaplastic Sarcoma of the Kidney.
Sarcoma
Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a "spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant".
Sarcoma, Clear Cell
Pediatric Renal Tumors: Updates in the Molecular Era.
Seizures
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.
Seminoma
Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
Sertoli Cell Tumor
Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features of DICER1 syndrome.
Sertoli-Leydig Cell Tumor
A family with Sertoli-Leydig cell tumour, multinodular goiter, and DICER1 mutation.
Sertoli-Leydig Cell Tumor
A novel DICER1 mutation identified in a female with ovarian Sertoli-Leydig cell tumor and multinodular goiter: a case report.
Sertoli-Leydig Cell Tumor
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Sertoli-Leydig Cell Tumor
Absence of DICER1, CTCF, RPL22, DNMT3A, TRRAP, IDH1 and IDH2 hotspot mutations in patients with various subtypes of ovarian carcinomas.
Sertoli-Leydig Cell Tumor
An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors.
Sertoli-Leydig Cell Tumor
An Unusual Enteric Yolk Sac Tumor: First Report of an Ovarian Germ Cell Tumor Associated With a Germline Pathogenic Variant in DICER1.
Sertoli-Leydig Cell Tumor
Deep sequencing reveals spatially distributed distinct hotspot mutations in DICER1-related multinodular goiter.
Sertoli-Leydig Cell Tumor
Detection of the DICER1 hotspot mutation alongside immunohistochemical analysis may provide a better diagnostic measure for ovarian Sertoli-Leydig cell tumors.
Sertoli-Leydig Cell Tumor
DICER1 and FOXL2 Mutation Status Correlates With Clinicopathologic Features in Ovarian Sertoli-Leydig Cell Tumors.
Sertoli-Leydig Cell Tumor
DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.
Sertoli-Leydig Cell Tumor
DICER1 exons 25 and 26 mutations are rare in common human tumours besides Sertoli-Leydig cell tumour.
Sertoli-Leydig Cell Tumor
DICER1 hot-spot mutations in ovarian gynandroblastoma.
Sertoli-Leydig Cell Tumor
DICER1 hotspot mutations in ovarian Sertoli-Leydig cell tumors: a potential association with androgenic effects.
Sertoli-Leydig Cell Tumor
DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.
Sertoli-Leydig Cell Tumor
DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.
Sertoli-Leydig Cell Tumor
DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors.
Sertoli-Leydig Cell Tumor
DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know.
Sertoli-Leydig Cell Tumor
DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours.
Sertoli-Leydig Cell Tumor
DICER1 Syndrome.
Sertoli-Leydig Cell Tumor
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Sertoli-Leydig Cell Tumor
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Sertoli-Leydig Cell Tumor
Embryonal rhabdomyosarcoma in a patient with a heterozygous frameshift variant in the DICER1 gene and additional manifestations of the DICER1 syndrome.
Sertoli-Leydig Cell Tumor
Evaluation of molecular analysis in challenging ovarian sex cord-stromal tumours: a review of 50 cases.
Sertoli-Leydig Cell Tumor
Extending the phenotypes associated with DICER1 mutations.
Sertoli-Leydig Cell Tumor
Familial multinodular goiter and Sertoli-Leydig cell tumors associated with a large intragenic in-frame
Sertoli-Leydig Cell Tumor
Genetic Causes of Rare Pediatric Ovarian Tumors.
Sertoli-Leydig Cell Tumor
Genetics and genomics of ovarian sex cord-stromal tumors.
Sertoli-Leydig Cell Tumor
Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides.
Sertoli-Leydig Cell Tumor
Germline and Somatic DICER1 Mutations in a Well-Differentiated Fetal Adenocarcinoma of the Lung.
Sertoli-Leydig Cell Tumor
Germline and somatic DICER1 mutations in familial and sporadic liver tumors.
Sertoli-Leydig Cell Tumor
Gynecologic and reproductive health in patients with pathogenic germline variants in DICER1.
Sertoli-Leydig Cell Tumor
Hereditary ovarian tumour syndromes: current update on genetics and imaging.
Sertoli-Leydig Cell Tumor
Imaging of DICER1 syndrome.
Sertoli-Leydig Cell Tumor
Judicious DICER1 testing and surveillance imaging facilitates early diagnosis and cure of pleuropulmonary blastoma.
Sertoli-Leydig Cell Tumor
Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report.
Sertoli-Leydig Cell Tumor
Mutiple DICER1-related lesions associated with a germline deep intronic mutation.
Sertoli-Leydig Cell Tumor
Ovarian Sertoli-Leydig Cell Tumor with Elevated Inhibin B as a Cause of Secondary Amenorrhea in an Adolescent with Germ Line DICER1 Mutation.
Sertoli-Leydig Cell Tumor
Ovarian Sertoli-Leydig Cell Tumor, Multinodular Goiter, Cystic Nephromas and DICER1 Mutations: Case Report and Literature Review.
Sertoli-Leydig Cell Tumor
Ovarian sex cord-stromal tumors in patients with probable or confirmed germline DICER1 mutations.
Sertoli-Leydig Cell Tumor
Ovarian Sex Cord-Stromal Tumors.
Sertoli-Leydig Cell Tumor
Ovarian sex cord-stromal tumours: an update in recent molecular advances.
Sertoli-Leydig Cell Tumor
Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry.
Sertoli-Leydig Cell Tumor
Pediatric imaging in DICER1 syndrome.
Sertoli-Leydig Cell Tumor
Pleuropulmonary blastoma-like peritoneal sarcoma: a newly described malignancy associated with biallelic DICER1 pathogenic variation.
Sertoli-Leydig Cell Tumor
Pleuropulmonary Blastoma: More Than a Lung Neoplasm of Childhood.
Sertoli-Leydig Cell Tumor
Practical roles for molecular diagnostic testing in ovarian adult granulosa cell tumour, Sertoli-Leydig cell tumour, microcystic stromal tumour and their mimics.
Sertoli-Leydig Cell Tumor
Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors.
Sertoli-Leydig Cell Tumor
Second primary rhabdomyosarcoma of the uterine cervix presenting with synchronous ovarian Sertoli-Leydig cell tumor: An illustrative case of DICER1 syndrome.
Sertoli-Leydig Cell Tumor
Sertoli-Leydig cell tumor in two siblings with DICER1 syndrome: A case report and literature review.
Sertoli-Leydig Cell Tumor
Sertoli-Leydig cell tumor, thyroid follicular carcinoma and rhabdomyosarcoma of the uterine cervix in a prepubertal girl with pathogenic germline variant in DICER1 gene.
Sertoli-Leydig Cell Tumor
Sertoli-Leydig Cell Tumour and DICER1 Mutation: A Case Report and Review of the Literature.
Sertoli-Leydig Cell Tumor
Somatic tumour testing establishes that bilateral DICER1-associated ovarian Sertoli-Leydig cell tumours represent independent primary neoplasms.
Sertoli-Leydig Cell Tumor
Spectrum of DICER1 Germline Pathogenic Variants in Ovarian Sertoli-Leydig Cell Tumor.
Sertoli-Leydig Cell Tumor
Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features of DICER1 syndrome.
Sertoli-Leydig Cell Tumor
The co-occurrence of an ovarian Sertoli-Leydig cell tumor with a thyroid carcinoma is highly suggestive of a DICER1 syndrome.
Sertoli-Leydig Cell Tumor
The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors.
Sertoli-Leydig Cell Tumor
The prevalence of DICER1 pathogenic variation in population databases.
Sertoli-Leydig Cell Tumor
Thoracic Sertoli-Leydig cell tumor: An alternative type of pleuropulmonary blastoma associated with DICER1 variation.
Sertoli-Leydig Cell Tumor
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Sertoli-Leydig Cell Tumor
Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.
Sertoli-Leydig Cell Tumor
[A family with a congenital DICER1 mutation].
Sertoli-Leydig Cell Tumor
[Ovarian Sertoli-Leydig cell tumors: DICER1 hotspot mutations and associated clinicopathological features].
Sertoli-Leydig Cell Tumor
[The pathology of hereditary ovarian tumors].
Severe Acute Respiratory Syndrome
An isoform of Dicer protects mammalian stem cells against multiple RNA viruses.
Sex Cord-Gonadal Stromal Tumors
A family with Sertoli-Leydig cell tumour, multinodular goiter, and DICER1 mutation.
Sex Cord-Gonadal Stromal Tumors
A survey of DICER1 hotspot mutations in ovarian and testicular sex cord-stromal tumors.
Sex Cord-Gonadal Stromal Tumors
DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.
Sex Cord-Gonadal Stromal Tumors
DICER1 hot-spot mutations in ovarian gynandroblastoma.
Sex Cord-Gonadal Stromal Tumors
DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.
Sex Cord-Gonadal Stromal Tumors
DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know.
Sex Cord-Gonadal Stromal Tumors
DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry.
Sex Cord-Gonadal Stromal Tumors
Extending the phenotypes associated with DICER1 mutations.
Sex Cord-Gonadal Stromal Tumors
Germ-line deletion in DICER1 revealed by a novel MLPA assay using synthetic oligonucleotides.
Sex Cord-Gonadal Stromal Tumors
Germline mutations of DICER1 in Chinese women with BRCA1/BRCA2-negative familial breast cancer.
Sex Cord-Gonadal Stromal Tumors
Identification of two 14q32 deletions involving DICER1 associated with the development of DICER1-related tumors.
Sex Cord-Gonadal Stromal Tumors
Ovarian sex cord-stromal tumors in patients with probable or confirmed germline DICER1 mutations.
Sex Cord-Gonadal Stromal Tumors
Ovarian sex cord-stromal tumors, pleuropulmonary blastoma and DICER1 mutations: A report from the International Pleuropulmonary Blastoma Registry.
Sex Cord-Gonadal Stromal Tumors
Pediatric imaging in DICER1 syndrome.
Sex Cord-Gonadal Stromal Tumors
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Sex Cord-Gonadal Stromal Tumors
Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis.
Sex Cord-Gonadal Stromal Tumors
Recurrent gynandroblastoma of the ovary with germline DICER1 mutation: A case report and review of the literature.
Sex Cord-Gonadal Stromal Tumors
Sertoli-Leydig cell tumor in two siblings with DICER1 syndrome: A case report and literature review.
Sex Cord-Gonadal Stromal Tumors
Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.
Sex Cord-Gonadal Stromal Tumors
Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT): A Morphologic and Molecular Study of 26 Cases Confirms Recurrent NCOA1-3 Rearrangement.
Sex Cord-Gonadal Stromal Tumors
[Ovarian Sertoli-Leydig cell tumors: DICER1 hotspot mutations and associated clinicopathological features].
Skin Neoplasms
Expression Levels of the microRNA Processing Enzymes Drosha and Dicer in Epithelial Skin Cancer.
Skin Neoplasms
Up-regulated Dicer expression in patients with cutaneous melanoma.
Smoldering Multiple Myeloma
Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients.
Smooth Muscle Tumor
Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.
Spinal Cord Injuries
Functional requirement of dicer1 and miR-17-5p in reactive astrocyte proliferation after spinal cord injury in the mouse.
Spinocerebellar Ataxias
Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets.
Spondylitis, Ankylosing
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Spondylitis, Ankylosing
Expression levels of the microRNA maturing microprocessor complex components; Drosha, Dicer, and DGCR8 in PBMCs from ankylosing spondylitis patients.
Squamous Cell Carcinoma of Head and Neck
A low dicer expression is associated with resistance to 5-FU-based chemoradiotherapy and a shorter overall survival in patients with oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells.
Squamous Cell Carcinoma of Head and Neck
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Squamous Cell Carcinoma of Head and Neck
Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma.
Starvation
The convergence of autophagy, small RNA and the stress response - implications for transgenerational epigenetic inheritance in plants.
Stomach Neoplasms
Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination.
Stomach Neoplasms
Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer.
Stomach Neoplasms
Cytoplasmic Drosha Is Aberrant in Precancerous Lesions of Gastric Carcinoma and Its Loss Predicts Worse Outcome for Gastric Cancer Patients.
Stomach Neoplasms
Decreased expression of DICER1 in gastric cancer.
Stomach Neoplasms
Dicer increases the indication for trastuzumab treatment in gastric cancer patients via overexpression of human epidermal growth factor receptor 2.
Stomach Neoplasms
DROSHA rs10719 T>C is associated with lymph node metastasis and clinical stage of gastric cancer patients.
Stomach Neoplasms
Drosha-independent miR-6778-5p strengthens gastric cancer stem cell stemness via regulation of cytosolic one-carbon folate metabolism.
Stomach Neoplasms
Dysregulation of microRNA biosynthesis enzyme Dicer plays an important role in gastric cancer progression.
Stomach Neoplasms
Exosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer.
Stomach Neoplasms
Genetic variants in miRNA machinery genes associated with clinicopathological characteristics and outcomes of gastric cancer patients.
Stomach Neoplasms
MicroRNA-107, an Oncogene MicroRNA that Regulates Tumor Invasion and Metastasis By Targeting DICER1 in Gastric Cancer: MiR-107 promotes gastric cancer invasion and metastasis.
Stomach Neoplasms
Nuclear Drosha enhances cell invasion via an EGFR-ERK1/2-MMP7 signaling pathway induced by dysregulated miRNA-622/197 and their targets LAMC2 and CD82 in gastric cancer.
Stomach Neoplasms
Single-nucleotide polymorphisms of microRNA processing machinery genes are associated with risk for gastric cancer.
Stomach Neoplasms
Systematic evaluation of the miRNA-ome and its downstream effects on mRNA expression identifies gastric cancer progression.
Stomach Neoplasms
Targeting the Production of Oncogenic MicroRNAs with Multimodal Synthetic Small Molecules.
Stomach Neoplasms
The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer.
Stomach Neoplasms
The RNA-Binding Protein DDX18 Promotes Gastric Cancer by Affecting the Maturation of MicroRNA-21.
Stomach Neoplasms
Transcript Level of MicroRNA Processing Elements in Gastric Cancer.
Stomach Neoplasms
[A negative correlation between Drosha expression and gastric adenocarcinoma malignancy and invasion].
Stomach Neoplasms
[Knockdown of Drosha promotes chemosensitivity of epirubicin for gastric cancer MGC-803 cells].
Supratentorial Neoplasms
Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a "spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant".
Telangiectasia, Hereditary Hemorrhagic
Deregulation of Drosha in the pathogenesis of hereditary hemorrhagic telangiectasia.
Telangiectasia, Hereditary Hemorrhagic
Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia.
Telangiectasis
Deregulation of Drosha in the pathogenesis of hereditary hemorrhagic telangiectasia.
Telangiectasis
Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia.
Teratoma
Malignant teratoid tumor of the thyroid gland: an aggressive primitive multiphenotypic malignancy showing organotypical elements and frequent DICER1 alterations-is the term "thyroblastoma" more appropriate?
Teratoma
Malignant teratomas of the thyroid gland: clinico-radiologic and cytomorphologic features of a rare entity.
Teratoma
Presacral malignant teratoid neoplasm in association with pathogenic DICER1 variation.
Teratoma
Recurrent DICER1 Hotspot Mutations in Malignant Thyroid Gland Teratomas: Molecular Characterization and Proposal for a Separate Classification.
Teratoma
Successful Management of a Patient with Malignant Thyroid Teratoma.
Teratoma
THE "-OMAS" and "-OPIAS": Targeted and Philosophical Considerations Regarding Hamartomas, Choristomas, Teratomas, Ectopias, and Heterotopias in Pediatric Otorhinolaryngologic Pathology.
Teratozoospermia
Integrative analysis of the human cis-antisense gene pairs, miRNAs and their transcription regulation patterns.
Thrombosis
Analysis of the Association Between MicroRNA Biogenesis Gene Polymorphisms and Venous Thromboembolism in Koreans.
Thyroid Cancer, Papillary
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma.
Thyroid Cancer, Papillary
DICER1 mutations are frequent in adolescent-onset papillary thyroid carcinoma.
Thyroid Cancer, Papillary
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression.
Thyroid Cancer, Papillary
Racial Differences in Expression Levels of miRNA Machinery-Related Genes, Dicer, Drosha, DGCR8, and AGO2, in Asian Korean Papillary Thyroid Carcinoma and Comparative Validation Using the Cancer Genome Atlas.
Thyroid Cancer, Papillary
Role of Dicer1 in thyroid cell proliferation and differentiation.
Thyroid Diseases
A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype.
Thyroid Diseases
Cytomorphologic features of thyroid disease in patients with DICER1 mutations: A report of cytology-histopathology correlation in 7 patients.
Thyroid Diseases
DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.
Thyroid Diseases
DICER1 gene alterations in thyroid diseases.
Thyroid Diseases
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Thyroid Neoplasms
A Genome-First Approach to Characterize DICER1 Pathogenic Variant Prevalence, Penetrance, and Phenotype.
Thyroid Neoplasms
A Positive Feedback Loop Between DICER1 and Differentiation Transcription Factors Is Important for Thyroid Tumorigenesis.
Thyroid Neoplasms
Analyzing the Role of DICER1 Germline Variations in Papillary Thyroid Carcinoma.
Thyroid Neoplasms
Clinical and Molecular Characteristics May Alter Treatment Strategies of Thyroid Malignancies in DICER1-syndrome.
Thyroid Neoplasms
Cytomorphologic features of thyroid disease in patients with DICER1 mutations: A report of cytology-histopathology correlation in 7 patients.
Thyroid Neoplasms
Development of metastatic poorly differentiated thyroid cancer from a sub-centimeter papillary thyroid carcinoma in a young patient with a germline MET mutation - association or random chance?
Thyroid Neoplasms
Dicer expression and microRNA dysregulation associate with aggressive features in thyroid cancer.
Thyroid Neoplasms
DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.
Thyroid Neoplasms
DICER1 mutations are frequent in adolescent-onset papillary thyroid carcinoma.
Thyroid Neoplasms
DICER1 Syndrome and Cancer Predisposition: From a Rare Pediatric Tumor to Lifetime Risk.
Thyroid Neoplasms
DICER1-Mutated Botryoid Fibroepithelial Polyp of the Parotid Duct: Report of the First Case.
Thyroid Neoplasms
DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome: a unique constellation of neoplastic conditions.
Thyroid Neoplasms
Exploring the association between DICER1 mutations and differentiated thyroid carcinoma.
Thyroid Neoplasms
Familial non-medullary thyroid carcinoma: clinico-pathological features, current knowledge and novelty regarding genetic risk factors.
Thyroid Neoplasms
Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness.
Thyroid Neoplasms
Macrofollicular variant follicular thyroid tumors are DICER1 mutated and exhibit distinct histological features.
Thyroid Neoplasms
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Thyroid Neoplasms
Neoplasm Risk Among Individuals With a Pathogenic Germline Variant in DICER1.
Thyroid Neoplasms
Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry.
Thyroid Neoplasms
Poorly differentiated thyroid carcinoma of childhood and adolescence: a distinct entity characterized by DICER1 mutations.
Thyroid Neoplasms
Prevalence and Spectrum of DICER1 Mutations in Adult-onset Thyroid Nodules with Indeterminate Cytology.
Thyroid Neoplasms
PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.
Thyroid Neoplasms
Quantification of thyroid cancer and multinodular goiter risk in the DICER1 syndrome: a family-based cohort study.
Thyroid Neoplasms
Recurrent DICER1 Hotspot Mutations in Malignant Thyroid Gland Teratomas: Molecular Characterization and Proposal for a Separate Classification.
Thyroid Neoplasms
Role of Dicer1 in thyroid cell proliferation and differentiation.
Thyroid Neoplasms
Somatic DICER1 Mutations in a Pubertal Girl with Cervical Embryonal Rhabdomyosarcoma and Papillary Thyroid Adenoma.
Thyroid Neoplasms
The co-occurrence of an ovarian Sertoli-Leydig cell tumor with a thyroid carcinoma is highly suggestive of a DICER1 syndrome.
Thyroid Neoplasms
[DICER1 mutated, solid/trabecular thyroid papillary carcinoma in an 11-year-old child].
Thyroid Neoplasms
[Hereditary predispositions to follicular thyroid tumors].
Thyroid Nodule
A Japanese Family with DICER1 Syndrome Found in Childhood-Onset Multinodular Goitre.
Thyroid Nodule
Cytomorphologic features of thyroid disease in patients with DICER1 mutations: A report of cytology-histopathology correlation in 7 patients.
Thyroid Nodule
DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.
Thyroid Nodule
DICER1 mutations are frequent in adolescent-onset papillary thyroid carcinoma.
Thyroid Nodule
Multinodular Goiter Progression Toward Malignancy in a Case of DICER1 Syndrome: Histologic and Molecular Alterations.
Thyroid Nodule
Prevalence and Spectrum of DICER1 Mutations in Adult-onset Thyroid Nodules with Indeterminate Cytology.
Triple Negative Breast Neoplasms
Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison.
Triple Negative Breast Neoplasms
Expression of Dicer and Drosha in triple-negative breast cancer.
Triple Negative Breast Neoplasms
MiR-18a upregulation decreases Dicer expression and confers paclitaxel resistance in triple negative breast cancer.
Triple Negative Breast Neoplasms
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.
Tuberculosis
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.
Tuberculosis
Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A.
Tuberous Sclerosis
An update on the genetics of benign pituitary adenomas in children and adolescents.
Tuberous Sclerosis
Gynecological lesions in hereditary cancer predisposition syndromes.
Tuberous Sclerosis
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Uremia
Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia.
Ureteral Obstruction
Dicer deficiency in proximal tubules exacerbates renal injury and tubulointerstitial fibrosis and upregulates Smad2/3.
Urinary Bladder Neoplasms
Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells.
Urinary Bladder Neoplasms
Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer.
Urinary Bladder Neoplasms
EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.
Urinary Bladder Neoplasms
Genetic variation in DROSHA 3'UTR regulated by hsa-miR-27b is associated with bladder cancer risk.
Urinary Bladder Neoplasms
microRNA-18a, a member of the oncogenic miR-17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells.
Urinary Bladder Neoplasms
Reduction of protein kinase C ? (PKC-?) promote apoptosis via down-regulation of Dicer in bladder cancer.
Urogenital Diseases
DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know.
Uterine Cervical Neoplasms
Calcitriol increases Dicer expression and modifies the microRNAs signature in SiHa cervical cancer cells.
Uterine Cervical Neoplasms
Down-regulation of Dicer expression in cervical cancer tissues.
Uterine Cervical Neoplasms
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha.
Uterine Cervical Neoplasms
Interference with endogenous EZH2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression.
Uterine Cervical Neoplasms
Prognostic significance of low DICER expression regulated by miR-130a in cervical cancer.
Uterine Cervical Neoplasms
Proteomic identification of target proteins following Drosha knockdown in cervical cancer.
Uterine Cervical Neoplasms
Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.
Vaccinia
Cleavage of Dicer protein by I7 protease during vaccinia virus infection.
Vascular Diseases
Deregulation of Drosha in the pathogenesis of hereditary hemorrhagic telangiectasia.
Vascular System Injuries
Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair.
Vascular System Injuries
Dicer promotes endothelial recovery and limits lesion formation after vascular injury through miR-126-5p.
Vesico-Ureteral Reflux
Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma.
Vesicular Stomatitis
Cellular microRNAs Repress Vesicular Stomatitis Virus but Not Theiler's Virus Replication.
Vesicular Stomatitis
Characterization and mapping of RNase III cleavage sites in VSV genome RNA.
Vesicular Stomatitis
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression.
Vesicular Stomatitis
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Vesicular Stomatitis
Vero cells as a model to study the effects of adenoviral gene delivery vectors on the RNAi system in context of viral infection.
Virus Diseases
Characterization of shrimp Drosha in virus infection.
Virus Diseases
Cleavage of Dicer protein by I7 protease during vaccinia virus infection.
Virus Diseases
Cross-species comparative analysis of Dicer proteins during Sindbis virus infection.
Virus Diseases
Dicer 1 of Candida albicans cleaves plant viral dsRNA in vitro and provides tolerance in plants against virus infection.
Virus Diseases
Dicer functions transcriptionally and posttranscriptionally in a multilayer antiviral defense.
Virus Diseases
Dicer is involved in protection against influenza A virus infection.
Virus Diseases
Dicer-2 processes diverse viral RNA species.
Virus Diseases
Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies.
Virus Diseases
Distinct requirements of microRNAs in NK cell activation, survival, and function.
Virus Diseases
Drosha as an interferon-independent antiviral factor.
Virus Diseases
Endogenous siRNAs: regulators of internal affairs.
Virus Diseases
Establishment of Neurospora crassa as a model organism for fungal virology.
Virus Diseases
Evidence for a cytoplasmic microprocessor of pri-miRNAs.
Virus Diseases
Functional analysis of a crustacean microRNA in host-virus interactions.
Virus Diseases
Human DICER helicase domain recruits PKR and modulates its antiviral activity.
Virus Diseases
Increased Viral Dissemination in the Brain and Lethality in MCMV-Infected, Dicer-Deficient Neonates.
Virus Diseases
Opposing forces fight over the same ground to regulate interferon signaling.
Virus Diseases
Reduced Dicer expression in the cord blood of infants admitted with severe respiratory syncytial virus disease.
Virus Diseases
Role of RNA interference (RNAi) in dengue virus replication and identification of NS4B as an RNAi suppressor.
Virus Diseases
Small creatures use small RNAs to direct antiviral defenses.
Virus Diseases
Super-induction of Dicer-2 expression by alien double-stranded RNAs: an evolutionary ancient response to viral infection?
Virus Diseases
The convergence of autophagy, small RNA and the stress response - implications for transgenerational epigenetic inheritance in plants.
Virus Diseases
The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila.
Virus Diseases
The dsRNA binding protein family: critical roles, diverse cellular functions.
Virus Diseases
The Single von Willebrand factor C-domain protein (SVC) coding gene is not involved in the hymenoptaecin upregulation after Israeli acute paralysis virus (IAPV) injection in the bumblebee Bombus terrestris.
Virus Diseases
Transcriptional response of immune-related genes after endogenous expression of VP1 and exogenous exposure to VP1-based VLPs and CPV virions in lepidopteran cell lines.
Virus Diseases
Transfection of BmCPV genomic dsRNA in silkmoth-derived Bm5 cells: Stability and interactions with the core RNAi machinery.
Virus Diseases
Viral Infection and Stress Affect Protein Levels of Dicer 2 and Argonaute 2 in Drosophila melanogaster.
Virus Diseases
Viral RNAi Suppressor Reversibly Binds siRNA to Outcompete Dicer and RISC via Multiple Turnover.
von Hippel-Lindau Disease
Gynecological lesions in hereditary cancer predisposition syndromes.
von Hippel-Lindau Disease
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Werner Syndrome
A gene encoding an RNase D exonuclease-like protein is required for post-transcriptional silencing in Arabidopsis.
Werner Syndrome
Comparative sequence analysis of ribonucleases HII, III, II PH and D.
Werner Syndrome
Familial non-medullary thyroid cancer: unraveling the genetic maze.
Werner Syndrome
Familial non-medullary thyroid carcinoma: clinico-pathological features, current knowledge and novelty regarding genetic risk factors.
Werner Syndrome
Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs.
West Nile Fever
Mosquito Small RNA Responses to West Nile and Insect-Specific Virus Infections in Aedes and Culex Mosquito Cells.
Wilms Tumor
A complex DICER1 syndrome phenotype associated with a germline pathogenic variant affecting the RNase IIIa domain of DICER1.
Wilms Tumor
Biallelic DICER1 mutations occur in Wilms tumours.
Wilms Tumor
Chromosomal anomalies at 1q, 3, 16q, and mutations of SIX1 and DROSHA genes underlie Wilms tumor recurrences.
Wilms Tumor
DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma.
Wilms Tumor
DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome.
Wilms Tumor
Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome.
Wilms Tumor
Extending the phenotypes associated with DICER1 mutations.
Wilms Tumor
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in the Childhood Cancer Survivor Study.
Wilms Tumor
Hotspot mutations in DICER1 causing GLOW Syndrome-associated macrocephaly via modulation of specific microRNA populations results in activation of PI3K/ATK/mTOR signaling.
Wilms Tumor
Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour.
Wilms Tumor
Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation.
Wilms Tumor
Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour.
Wilms Tumor
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.
Wilms Tumor
The development of Wilms tumor: from WT1 and microRNA to animal models.
Wilms Tumor
Wilms tumor, pleuropulmonary blastoma, and DICER1: case report and literature review.
Yellow Fever
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.
Zika Virus Infection
Dicer-2 Regulates Resistance and Maintains Homeostasis against Zika Virus Infection in Drosophila.
Zika Virus Infection
The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.