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Disease on EC 3.1.21.1 - deoxyribonuclease I

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Aberrant Crypt Foci
Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.
Inhibition of azoxymethane initiated colon tumor and aberrant crypt foci development by bovine lactoferrin administration in F344 rats.
Inhibition of initiation and early stage development of aberrant crypt foci and enhanced natural killer activity in male rats administered bovine lactoferrin concomitantly with azoxymethane.
Inhibitory effects of bovine lactoferrin on intestinal polyposis in the Apc(Min) mouse.
Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat.
Abscess
Colicin Z, a structurally and functionally novel colicin type that selectively kills enteroinvasive Escherichia coli and Shigella strains.
Differential excretion of leucocyte granule components in inflammatory bowel disease: implications for pathogenesis.
Evaluation of Direct and Cell-Mediated Lactoferrin Gene Therapy for the Maxillofacial Area Abscesses in Rats.
Lactoferrin: its role as a Ga-67-binding protein in polymorphonuclear leukocytes.
Report on an outbreak of postinjection abscesses due to Mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic DNA polymerase chain reaction.
The use of streptokinase and streptodornase in pelvic abscesses; preliminary report.
[Enzyme DNA-ase use in patients with maxillofacial abscesses and phlegmons]
[Therapy of pelvic abscess by the vaginal route using streptokinase and streptodornase]
Acidosis
Cytidine deaminase activity in synovial fluid of patients with rheumatoid arthritis: relation to lactoferrin, acidosis, and cartilage proteoglycan release.
EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
Acidosis, Lactic
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.
Acne Vulgaris
A randomized, double-blind, placebo-controlled trial to determine the efficacy and safety of lactoferrin with vitamin E and zinc as an oral therapy for mild to moderate acne vulgaris.
A Systematic Review of Lactoferrin Use in Dermatology.
Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris.
Efficacy and tolerability of oral lactoferrin supplementation in mild to moderate acne vulgaris: an exploratory study.
Isotretinoin therapy changes the expression of antimicrobial peptides in acne vulgaris.
Acquired Immunodeficiency Syndrome
Behavior of diphtheria toxin T domain containing substitutions that block normal membrane insertion at Pro345 and Leu307: control of deep membrane insertion and coupling between deep insertion of hydrophobic subdomains.
Behavior of the deeply inserted helices in diphtheria toxin T domain: helices 5, 8, and 9 interact strongly and promote pore formation, while helices 6/7 limit pore formation.
Cationic liposome-mediated expression of HIV-regulated luciferase and diphtheria toxin a genes in HeLa cells infected with or expressing HIV.
Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed.
Consumption of transgenic cows' milk containing human lactoferrin results in beneficial changes in the gastrointestinal tract and systemic health of young pigs.
Cytomegalovirus viremia, mortality, and end-organ disease among patients with AIDS receiving potent antiretroviral therapies.
Establishment of a quality assurance program for human immunodeficiency virus type 1 DNA polymerase chain reaction assays by the AIDS Clinical Trials Group. ACTG PCR Working Group, and the ACTG PCR Virology Laboratories.
Filtration and local synthesis of lacrimal proteins in acquired immunodeficiency syndrome.
Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation.
Inhibitors of retroviral DNA polymerase: their implication in the treatment of AIDS.
Interactions between HIV and hepatitis B virus in homosexual men: effects on the natural history of infection.
Interstrain variation in the human cytomegalovirus DNA polymerase sequence and its effect on genotypic diagnosis of antiviral drug resistance. Adult AIDS Clinical Trials Group CMV Laboratories.
Lactoferrin infant feeding trial_Canada (LIFT_Canada): protocol for a randomized trial of adding lactoferrin to feeds of very-low-birth-weight preterm infants.
Lactoferrin interacts with SPLUNC1 to attenuate lipopolysaccharide-induced inflammation of human nasal epithelial cells via down-regulated MEK1/2-MAPK signaling.
Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity.
Plasma lactoferrin levels are decreased in end-stage AIDS patients.
Rapid and constant detection of HIV antibody response in saliva of HIV-infected patients; selective distribution of anti-HIV activity in the IgG isotype.
Sequence-selective binding to DNA of cis- and trans- butamidine analogues of the anti-Pneumocystis carinii pneumonia drug pentamidine.
Single amino acid change in DNA polymerase is associated with foscarnet resistance in a varicella-zoster virus strain recovered from a patient with AIDS.
Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS.
Standardisation of primers and an algorithm for HIV-1 diagnostic PCR evaluated in patients harbouring strains of diverse geographical origin. The Belgian AIDS Reference Laboratories.
Suppression of a dnaKJ Deletion by Multicopy dksA Results from Non-Feedback-Regulated Transcripts That Originate Upstream of the Major dksA Promoter.
Topography of diphtheria toxin A chain inserted into lipid vesicles.
Topography of helices 5-7 in membrane-inserted diphtheria toxin T domain: identification and insertion boundaries of two hydrophobic sequences that do not form a stable transmembrane hairpin.
Utility of urine and leukocyte cultures and plasma DNA polymerase chain reaction for identification of AIDS patients at risk for developing human cytomegalovirus disease.
[DNA-hydrolyzing IgG antibodies from the blood of patients with acquired immune deficiency syndrome]
[Serum and lacrimal proteins in acquired immunodeficiency syndrome]
Acute Coronary Syndrome
Correction to: Coronary Neutrophil Extracellular Trap Burden and Deoxyribonuclease Activity in ST-Elevation Acute Coronary Syndrome Are Predictors of ST-Segment Resolution and Infarct Size.
Early release of neutrophil markers of activation after direct stenting in patients with unstable angina.
Acute Kidney Injury
IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury.
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis.
Neutrophil activation in acute renal failure and sepsis.
Renal Dendritic Cells Ameliorate Nephrotoxic Acute Kidney Injury.
Renoprotective Effect of Lactoferrin against Chromium-Induced Acute Kidney Injury in Rats: Involvement of IL-18 and IGF-1 Inhibition.
Renoprotective Effects of DNAse-I Treatment in a Rat Model of Ischemia/Reperfusion-Induced Acute Kidney Injury.
Acute Lung Injury
A murine model of acute lung injury identifies growth factors to promote tissue repair and their biomarkers.
CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death.
DNaseI Protects against Paraquat-Induced Acute Lung Injury and Pulmonary Fibrosis Mediated by Mitochondrial DNA.
Effect of bovine lactoferrin as a novel therapeutic agent in a rat model of sepsis-induced acute lung injury.
Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.
Lactoferrin protects against lipopolysaccharide-induced acute lung injury in mice.
Neutrophil extracellular traps are indirectly triggered by lipopolysaccharide and contribute to acute lung injury.
Adenocarcinoma
A new medium-term rat colon bioassay applying neoplastic lesions as endpoints for detection of carcinogenesis modifiers-validation with known modifiers.
Altered actin polymerization dynamics in various malignant cell types: evidence for differential sensitivity to cytochalasin B.
Characterization of nuclear matrices prepared without salt extraction.
Clinicopathologic and immunohistochemical characteristics of bronchial gland cell type adenocarcinoma of the lung.
Diphtheria toxin effects on human cells in tissue culture.
DNA polymerase ? protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
Glycosaminoglycans of human colonic mucosa and colonic adenocarcinoma.
Identification of the primary site of metastatic adenocarcinoma in serous effusions. Value of an immunocytochemical panel added to the clinical arsenal.
Immunohistochemical detection of lactoferrin in different human glandular tissues with special reference to the exocrine pancreas.
Intermediate-sized filaments and specific markers in a human salivary gland adenocarcinoma cell line and its nude mouse tumors.
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.
Lactoferrin in benign hypertrophy and carcinomas of the prostatic gland.
Lactoferrin in human prostate tissue.
Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.
MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer.
Nanotheranostic Based Iron Oxide (Fe?O?) Saturated Lactoferrin Nanocapsules for Colonic Adenocarcinoma.
Neoplastic transformation of the endocervix associated with downregulation of lactoferrin expression.
Primary signet-ring cell carcinoma of the lung: histochemical and immunohistochemical characterization.
Sialoglycopeptides obtained from a transplantable rat colorectal adenocarcinoma: a comparison with those from normal colonic mucosa.
Targeting solid tumors via T cell receptor complementarity-determining region 3delta in an engineered antibody.
Theranostic multimodular potential of zinc-doped ferrite-saturated metal-binding protein-loaded novel nanocapsules in cancers.
Transferrin in normal and neoplastic endocervical tissues: distribution and receptor expression.
[Responsiveness and mechanisms of action of steroid hormones in human endometrial adenocarcinoma cells]
Adenocarcinoma in Situ
Neoplastic transformation of the endocervix associated with downregulation of lactoferrin expression.
Adenocarcinoma of Lung
Binding of Lactoferrin to IGBP1 Triggers Apoptosis in a Lung Adenocarcinoma Cell Line.
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma.
PAMAM/polyhedral nanogold-modified probes with DNAase catalysis for the amperometric electrochemical detection of metastasis-associated lung adenocarcinoma transcript 1.
Adenocarcinoma, Papillary
Composite tumor with papillary adenocarcinoma and squamous cell carcinoma of the esophagus: report of a case.
Adenolymphoma
Difference of immunohistochemical reactions in epithelial cells of adenolymphoma.
Immunohistochemical investigation of lysozyme, lactoferrin, alpha 1-antitrypsin, alpha 1-antichymotrypsin and ferritin in parotid gland tumors.
Adenoma
A new medium-term rat colon bioassay applying neoplastic lesions as endpoints for detection of carcinogenesis modifiers-validation with known modifiers.
Immunocytochemical detection of lactoferrin in human gastric carcinomas and adenomas.
Immunohistochemical demonstration of ceruloplasmin in follicular adenomas and thyroid carcinomas.
Immunohistochemical demonstration of lactoferrin in follicular adenomas and thyroid carcinomas.
Immunohistochemical localization of metal binding proteins in thyroid tissues and tumors.
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland.
Iron-binding proteins in thyroid tumours. An immunocytochemical study.
Lactoferrin, lysozyme, and beta 2-microglobulin levels in cerebrospinal fluid: differential indices of CNS inflammation.
Molecular Aspects of Colorectal Adenomas: The Interplay among Microenvironment, Oxidative Stress, and Predisposition.
Myoepitheliomas and myoepithelial adenomas of salivary gland origin. Immunohistochemical evaluation of filament proteins, S-100 alpha and beta, glial fibrillary acidic proteins, neuron-specific enolase, and lactoferrin.
New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis.
POLD1 and POLE Gene Mutations in Jewish Cohorts of Early-Onset Colorectal Cancer and of Multiple Colorectal Adenomas.
[The nature of the antigenic restructuring of tumors of the human prostate]
Adenoma, Pleomorphic
Immunofluorescence study of secretory epithelial markers in pleomorphic adenomas.
Immunohistochemical demonstration of lysozyme and lactoferrin in salivary pleomorphic adenomas.
Immunohistochemical investigation of lysozyme, lactoferrin, alpha 1-antitrypsin, alpha 1-antichymotrypsin and ferritin in parotid gland tumors.
Immunohistochemical localization of alpha 1-antitrypsin and alpha 1-antichymotrypsin in salivary pleomorphic adenomas.
Immunohistochemical study of four histologic types of parotid gland pleomorphic adenoma.
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.
Search for specific markers of neoplastic epithelial duct and myoepithelial cell lines established from human salivary gland and characterization of their growth in vitro.
Various expressions of modified myoepithelial cells in salivary pleomorphic adenoma. Immunohistochemical studies.
Adenomatous Polyps
Cancer prevention by bovine lactoferrin: from animal studies to human trial.
Adenoviridae Infections
Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells.
Bovine lactoferrin inhibits adenovirus infection by interacting with viral structural polypeptides.
Heparin-interacting sites of bovine lactoferrin are involved in anti-adenovirus activity.
Successful Use of Cidofovir in an Immunocompetent Child With Severe Adenoviral Sepsis.
Adrenocortical Carcinoma
Inhibition of adrenocortical carcinoma by diphtheria toxin mutant CRM197.
African Swine Fever
1H, 15N, and 13C resonance assignments for a 20 kDa DNA polymerase from African swine fever virus.
African swine fever virus-induced DNA polymerase is resistant to aphidicolin.
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus.
ASFV DNA polymerase extends recessed DNAs with catalytic efficiencies outperforming those exerted on gapped DNA substrates.
Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair.
Effect of interferon-alpha, interferon-gamma and tumour necrosis factor on African swine fever virus replication in porcine monocytes and macrophages.
Evidence for the evolution of ascoviruses from iridoviruses.
Genetic identification and nucleotide sequence of the DNA polymerase gene of African swine fever virus.
Human DNA Polymerase ? Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
Involvement of the reparative DNA polymerase pol x of african Swine Fever virus in the maintenance of viral genome stability in vivo.
Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.
Aggressive Periodontitis
A non-conservative, coding single-nucleotide polymorphism in the N-terminal region of lactoferrin is associated with aggressive periodontitis in an African-American, but not a Caucasian population.
Association between lactoferrin gene polymorphisms and aggressive periodontitis among Taiwanese patients.
Lactoferrin iron levels are reduced in saliva of patients with localized aggressive periodontitis.
Lysozyme and lactoferrin quantitation in the crevicular fluid.
One of two human lactoferrin variants exhibits increased antibacterial and transcriptional activation activities and is associated with localized juvenile periodontitis.
Peroxidases, lactoferrin and lysozyme in peripheral blood neutrophils, gingival crevicular fluid and whole saliva of patients with localized juvenile periodontitis.
Agranulocytosis
Release of lactoferrin by polymorphonuclear leukocytes after aerosol challenge with Escherichia coli.
Serum myeloperoxidase and lactoferrin in neutropenia.
Airway Obstruction
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis. Dornase Alfa Nebulizer Group.
Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation.
Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment.
Local dornase alfa treatment reduces NETs-induced airway obstruction during severe RSV infection.
Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months.
Small airway deposition of dornase alfa during exacerbations in cystic fibrosis; a randomized controlled clinical trial.
Small-airways deposition of dornase alfa in children with asthma and persistent airway obstruction.
[Clinical development of rhDNase in the United States]
[Diphtheria: a 'forgotten' disease?]
Albuminuria
In Vivo Imaging of Inflamed Glomeruli Reveals Dynamics of Neutrophil Extracellular Trap Formation in Glomerular Capillaries.
Aleutian Mink Disease
A fast and accurate method of detecting Aleutian mink disease virus in blood and tissues of chronically infected mink.
Alphavirus Infections
Inhibition of Mayaro virus infection by bovine lactoferrin.
Alveolar Bone Loss
Long-term sustainable dendritic cell-specific depletion murine model for periodontitis research.
Alzheimer Disease
A novel LDL-mimic nanocarrier for the targeted delivery of curcumin into the brain to treat Alzheimer's disease.
A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway.
Aluminum, altered transcription, and the pathogenesis of Alzheimer's disease.
Decreased salivary lactoferrin levels are specific to Alzheimer's disease.
Deposition of lactoferrin in fibrillar-type senile plaques in the brains of transgenic mouse models of Alzheimer's disease.
Dietary Lactoferrin Supplementation Prevents Memory Impairment and Reduces Amyloid-? Generation in J20 Mice.
DNA polymerase ? decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease.
DNA polymerase ? deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.
Early diagnosis of mild cognitive impairment and Alzheimer's disease based on salivary lactoferrin.
Effect of deoxyribonuclease I treatment for dementia in end-stage Alzheimer's disease: a case report.
Enhanced brain delivery of deferasirox-lactoferrin conjugates for iron chelation therapy in neurodegenerative disorders: in vitro and in vivo studies.
Intranasal Lactoferrin Enhances ?-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1? Pathways in an Alzheimer's Disease Mouse Model.
Lactoferrin Coupled Lower Generation PAMAM Dendrimers for Brain Targeted Delivery of Memantine in Aluminum-Chloride-Induced Alzheimer's Disease in Mice.
Lactoferrin for Mental Health: Neuro-Redox Regulation and Neuroprotective Effects across the Blood-Brain Barrier with Special Reference to Neuro-COVID-19.
Lactoferrin in cerebrospinal fluid and saliva is not a diagnostic biomarker for Alzheimer's disease in a mixed memory clinic population.
Lactoferrin induces cell surface retention of prion protein and inhibits prion accumulation.
Low levels of salivary lactoferrin may affect oral dysbiosis and contribute to Alzheimer's disease: A hypothesis.
Mining Clinical Case Reports to Identify New Lines of Investigation in Alzheimer's Disease: The Curious Case of DNase I.
Neuroprotection against apoptosis of SK-N-MC cells using RMP-7- and lactoferrin-grafted liposomes carrying quercetin.
Porphyromonas gingivalis Outer Membrane Vesicles as the Major Driver of and Explanation for Neuropathogenesis, the Cholinergic Hypothesis, Iron Dyshomeostasis, and Salivary Lactoferrin in Alzheimer's Disease.
Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy.
Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease.
Salivary lactoferrin as biomarker for Alzheimer's disease: Brain-immunity interactions.
Standardizing salivary lactoferrin measurements to obtain a robust diagnostic biomarker for Alzheimer's disease.
The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of A? burden through induction of APP amyloidogenic processing.
Tryptophan-Containing Dual Neuroprotective Peptides: Prolyl Endopeptidase Inhibition and Caenorhabditis elegans Protection from ?-Amyloid Peptide Toxicity.
Amnesia
Bacosides Encapsulated in Lactoferrin Conjugated PEG-PLA-PCL-OH Based Polymersomes Act as Epigenetic Modulator in Chemically Induced Amnesia.
Amyloidosis
A case of spheroid-type localized lactoferrin amyloidosis in the bronchus.
A novel localized amyloidosis associated with lactoferrin in the cornea.
Amyloidosis and Ocular Involvement: an Overview.
Classification of Secondary Corneal Amyloidosis and Involvement of Lactoferrin.
Familial subepithelial corneal amyloidosis (gelatinous drop-like corneal dystrophy): exclusion of linkage to lactoferrin gene.
Familial subepithelial corneal amyloidosis--a lactoferrin-related amyloidosis.
Lactoferrin Glu561Asp facilitates secondary amyloidosis in the cornea.
Localized amyloidosis of the seminal vesicle: identification of lactoferrin immunoreactivity in the amyloid material.
[A case of corneal lactoferrin amyloidosis secondary to trichiasis]
[Amyloidosis of the seminal vesicles: a local condition with no systemic impact.]
[Heterogeneity of seminal vesicle amyloid. Immunohistochemical detection of lactoferrin and amyloid of the prealbumin-transthyretin type]
Amyotrophic Lateral Sclerosis
RNA-instructed DNA polymerase activity in a cytoplasmic particulate fraction in brains from Guamanian patients.
Anaphylaxis
Dornase alfa. A review of its pharmacological properties and therapeutic potential in cystic fibrosis.
Lactoferrin acts as an adjuvant during influenza vaccination of neonatal mice.
Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration.
Ovalbumin fused with diphtheria toxin protects mice from ovalbumin induced anaphylactic shock.
Anemia
A STUDY OF THE ELIMINATION OF PHENOLSULPHONEPHTHALEIN IN VARIOUS EXPERIMENTAL LESIONS OF THE KIDNEY.
Are extrinsic black stains of teeth iron-saturated bovine lactoferrin and a sign of iron deficient anemia or iron overload?
Dnases in health and disease.
Dose effect of bovine lactoferrin fortification on diarrhea and respiratory tract infections in weaned infants with anemia: A randomized, controlled trial.
Effect of lactoferrin on consequences of acute experimental hemorrhagic anemia in rats.
Efficacy and safety of oral lactoferrin supplementation in combination with rHuEPO-beta for the treatment of anemia in advanced cancer patients undergoing chemotherapy: open-label, randomized controlled study.
Efficacy and tolerability of oral bovine lactoferrin compared to ferrous sulfate in pregnant women with iron deficiency anemia: a prospective controlled randomized study.
Efficacy of Lactoferrin Oral Administration in the Treatment of Anemia and Anemia of Inflammation in Pregnant and Non-pregnant Women: An Interventional Study.
Fermented goat's milk modulates immune response during iron deficiency anemia recovery.
Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.
Involvement of C-terminal structural elements of equine infectious anemia virus reverse transcriptase in DNA polymerase and ribonuclease H activities.
Lactoferrin efficacy versus ferrous sulfate in curing iron deficiency and iron deficiency anemia in pregnant women.
Lactoferrin for Prevention and Treatment of Anemia and Inflammation in Pregnant Women: A Comprehensive Review.
Lactoferrin for treating iron deficiency anemia in pregnancy: statistical concerns.
Lactoferrin in human neutrophilic polymorphonuclear leukocytes in relation to iron metabolism.
Lactoferrin levels in the gastric tissue of Helicobacter pylori-positive and -negative patients and its effect on anemia.
Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials.
Lactoferrin plus health education versus total dose infusion (TDI) of low-molecular weight (LMW) iron dextran for treating iron deficiency anemia (IDA) in pregnancy: a randomized controlled trial.
Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: a randomized clinical trial.
Lactoferrin versus iron hydroxide polymaltose complex for the treatment of iron deficiency anemia in children with cerebral palsy: a randomized controlled trial.
Mechanism of inhibition of HIV reverse transcriptase by toxiusol, a novel general inhibitor of retroviral and cellular DNA polymerases.
Mother's iron status, breastmilk iron and lactoferrin--are they related?
Preventive effect of lactoferrin intake on anemia in female long distance runners.
Production of recombinant porcine lactoferrin exhibiting antibacterial activity in methylotrophic yeast, Pichia pastoris.
Recombinant human lactoferrin treatment for global health issues: iron deficiency and acute diarrhea.
Safety and efficacy of lactoferrin versus ferrous sulphate in curing iron deficiency and iron deficiency anaemia in hereditary thrombophilia pregnant women: an interventional study.
Severe anemia due to parvovirus B19 in a silver haired boy.
Successful drainage of complex haemoserous malignant pleural effusion with a single modified low-dose intrapleural alteplase and dornase alfa.
Supplementation with a dietary multicomponent (Lafergin(®)) based on Ferric Sodium EDTA (Ferrazone(®)): results of an observational study.
The influence of lactoferrin, orally administered, on systemic iron homeostasis in pregnant women suffering of iron deficiency and iron deficiency anaemia.
The relationship of lactoferrin to the anemia of renal cell carcinoma.
Turnover of human lactoferrin in the rabbit.
[Effects of recombinant human lactoferrin on improving the iron status of IDA rats].
[Efficacy of iron saturated recombinant human lactoferrin on alleviating iron deficiency anemia in rats].
[Lactoferrin and perspectives for dietary prevention of anemia]
[Pathology and treatment of anemia in the elderly]
Anemia, Aplastic
Plasma lactoferrin content in neutropenic patients: effects of treatment with recombinant granulocyte-macrophage colony-stimulating factor.
Relationship of plasma lactoferrin content to neutrophil regeneration and bone marrow infusion.
Anemia, Hemolytic, Autoimmune
Refractory and Fatal Presentation of Severe Autoimmune Hemolytic Anemia in a Child With the DNASE1L3 Mutation Complicated With an Additional DOCK8 Variant.
Anemia, Iron-Deficiency
Efficacy and tolerability of oral bovine lactoferrin compared to ferrous sulfate in pregnant women with iron deficiency anemia: a prospective controlled randomized study.
Lactoferrin efficacy versus ferrous sulfate in curing iron deficiency and iron deficiency anemia in pregnant women.
Lactoferrin for Prevention and Treatment of Anemia and Inflammation in Pregnant Women: A Comprehensive Review.
Lactoferrin for treating iron deficiency anemia in pregnancy: statistical concerns.
Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials.
Lactoferrin plus health education versus total dose infusion (TDI) of low-molecular weight (LMW) iron dextran for treating iron deficiency anemia (IDA) in pregnancy: a randomized controlled trial.
Lactoferrin sequestration and its contribution to iron-deficiency anemia in Helicobacter pylori-infected gastric mucosa.
Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: a randomized clinical trial.
Lactoferrin versus iron hydroxide polymaltose complex for the treatment of iron deficiency anemia in children with cerebral palsy: a randomized controlled trial.
Preventive effect of lactoferrin intake on anemia in female long distance runners.
Recombinant human lactoferrin treatment for global health issues: iron deficiency and acute diarrhea.
Safety and efficacy of lactoferrin versus ferrous sulphate in curing iron deficiency and iron deficiency anaemia in hereditary thrombophilia pregnant women: an interventional study.
The influence of lactoferrin, orally administered, on systemic iron homeostasis in pregnant women suffering of iron deficiency and iron deficiency anaemia.
[Effects of recombinant human lactoferrin on improving the iron status of IDA rats].
[Efficacy of iron saturated recombinant human lactoferrin on alleviating iron deficiency anemia in rats].
[The characteristics of iron metabolism under iron-deficiency anemia and chronic disorders anemia].
Anemia, Megaloblastic
Vitamin B12--folate interrelations.
Anemia, Sickle Cell
Diagnostic Accuracy of HemotypeSC as a Point-of-Care Testing Device for Sickle Cell Disease: Findings from a Southwestern State in Nigeria and Implications for Patient Care in Resource-Poor Settings of sub-Saharan Africa.
Immunization of young infants with sickle cell disease with a Haemophilus influenzae type b saccharide-diphtheria CRM197 protein conjugate vaccine.
Lactoferrin (LF), prostaglandin E (PGE) and neutrophils in children with sickle cell disease (SCD)
Steady-state plasma lactoferrin levels in relation to infections and complications of sickle cell disease.
Anemia, Sideroblastic
Mitochondria in hematopoiesis and hematological diseases.
Aneurysm
Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction.
Angina Pectoris
Diagnostic use of serum deoxyribonuclease I activity as a novel early-phase marker in acute myocardial infarction.
Serum deoxyribonuclease I activity can be used as a novel marker of transient myocardial ischaemia: results in vasospastic angina pectoris induced by provocation test.
Serum deoxyribonuclease I can be used as a useful marker for diagnosis of death due to ischemic heart disease.
The chemistry and pharmacology of alkaloids and allied nitrogen compounds from Artemisia species: A review.
Angina, Stable
Acute neutrophil activation in direct stenting: comparison of stable and unstable angina patients.
Coronary stenting is associated with an acute increase in plasma myeloperoxidase in stable angina patients but not in patients with acute myocardial infarction.
Serum deoxyribonuclease I activity can be used as a sensitive marker for detection of transient myocardial ischaemia induced by percutaneous coronary intervention.
Serum deoxyribonuclease I can be used as a useful marker for diagnosis of death due to ischemic heart disease.
Angina, Unstable
Acute neutrophil activation in direct stenting: comparison of stable and unstable angina patients.
Diagnostic use of serum deoxyribonuclease I activity as a novel early-phase marker in acute myocardial infarction.
Early release of neutrophil markers of activation after direct stenting in patients with unstable angina.
Serum deoxyribonuclease I activity can be a useful diagnostic marker for the early diagnosis of unstable angina pectoris or non-ST-segment elevation myocardial infarction.
Aniridia
Analysis of protein composition and protein expression in the tear fluid of patients with congenital aniridia.
Anosmia
Is sporadic Alzheimer's disease associated with diphtheria toxin?
Anthrax
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen.
Antibody microarrays for native toxin detection.
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus.
Characterization of membrane translocation by anthrax protective antigen.
Comparative proteomics of the Mycobacterium leprae binding protein myelin P0: its implication in leprosy and other neurodegenerative diseases.
Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain.
Function, structure and regulation of the vacuolar (H+)-ATPases.
Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen.
Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells.
Humanized immunotoxins: a new generation of immunotoxins for targeted cancer therapy.
Identification of Conformational B-cell Epitopes in Diphtheria Toxin at Varying Temperatures Using Molecular Dynamics Simulations.
Mosquito inoculation: an alternative bioassay for toxins.
Novel Furin Inhibitors with Potent Anti-infectious Activity.
Oxidized ATP protection against anthrax lethal toxin.
Peptide toxins directed at the matrix dissolution systems of cancer cells.
Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore.
Prospects of Bacterial and Plant Protein-based Immunotoxins for Treatment of Cancer.
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases.
Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein.
Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.
Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis.
THE IMMUNIZING POWER OF NUCLEOHISTON AND OF HISTON.
Trojan horse or proton force: finding the right partner(s) for toxin translocation.
[Production and characteristics of monoclonal antibodies to the diphtheria toxin]
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Does the presence of ANCA in patients with ulcerative colitis necessarily imply renal involvement?
Aortic Aneurysm, Abdominal
Neutrophil leukotriene generation and pulmonary dysfunction after abdominal aortic aneurysm repair.
Appendicitis
Serum Procalcitonin and Lactoferrin in Detection of Acute Appendicitis; a Diagnostic Accuracy Study.
The Place of Calprotectin, Lactoferrin, and High-Mobility Group Box 1 Protein on Diagnosis of Acute Appendicitis with Children.
Arteriosclerosis
Correlation Between Arteriosclerosis and Periodontal Condition Assessed by Lactoferrin and ?1-Antitrypsin Levels in Gingival Crevicular Fluid.
THE PRODUCTION OF ARTERIOSCLEROSIS AND GLOMERULONEPHRITIS IN THE RABBIT BY INTRAVENOUS INJECTIONS OF DIPHTHERIA TOXIN.
Arthritis
A novel peptide derivative exhibits anti inflammatory and antioxidant activity in adjuvant induced arthritis in rats.
Anti-lactoferrin antibodies and other types of anti-neutrophil cytoplasmic antibodies (ANCA) in reactive arthritis and ankylosing spondylitis.
Desoxyribonuclease activity in the serum and spleen of rats with mycoplasma induced arthritis.
Diagnostic tests in patients with symptoms of keratoconjunctivitis sicca.
Eosinophil cationic protein in inflammatory synovial effusions as evidence of eosinophil involvement.
Fat-Produced Adipsin Regulates Inflammatory Arthritis.
Lactoferrin in synovial fluid of patients with inflammatory arthritis.
Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid.
Lactoferrin: A Roadmap to the Borderland between Caries and Periodontal Disease.
Oral administration of lactoferrin inhibits inflammation and nociception in rat adjuvant-induced arthritis.
Regulatory T cells control epitope spreading in autoimmune arthritis independent of cytotoxic T-lymphocyte antigen-4.
The effects of local administration of lactoferrin on inflammation in murine autoimmune and infectious arthritis.
[Correlation of DNase I in serum and synovial fluid with inflammatory activity in patients with rheumatoid arthritis].
[Information from a study of the nature of secondary immunodeficient states. II. Effect of destruction of dorsal hippocampus structures on the intensity of signs of adjuvant arthritis in rats and cutaneous reactions to diphtheria toxin in rabbits]
[The criteria of differentiated diagnostics of early arthritis on the basis of analysis of serum hyaluronidase and deoxyribonuclease activity].
Arthritis, Experimental
Designing lipid nanostructures for local delivery of biologically active macromolecules.
Effect of a derivatized tetrapeptide from lactoferrin on nitric oxide mediated matrix metalloproteinase-2 production by synovial fibroblasts in collagen-induced arthritis in rats.
Lactoferrin triggers in vitro proliferation of T cells of Lewis rats submitted to mycobacteria-induced adjuvant arthritis.
Liposomes as possible carriers for lactoferrin in the local treatment of inflammatory diseases.
The effect of oral administration of iron saturated-bovine lactoferrin encapsulated chitosan-nanocarriers on osteoarthritis.
[Effect of lactoferrin on the development of acute and chronic adjuvant arthritis]
[Information from a study of the nature of secondary immunodeficient states. II. Effect of destruction of dorsal hippocampus structures on the intensity of signs of adjuvant arthritis in rats and cutaneous reactions to diphtheria toxin in rabbits]
Arthritis, Gouty
[Correlation of DNase I in serum and synovial fluid with inflammatory activity in patients with rheumatoid arthritis].
Arthritis, Infectious
Lactoferrin and lysozyme levels in synovial fluid: differential indices of articular inflammation and degradation.
The effects of local administration of lactoferrin on inflammation in murine autoimmune and infectious arthritis.
Arthritis, Psoriatic
Cytidine deaminase and lactoferrin in inflammatory synovial fluids. Indicators of local polymorphonuclear cell function?
Arthritis, Reactive
Anti-lactoferrin antibodies and other types of anti-neutrophil cytoplasmic antibodies (ANCA) in reactive arthritis and ankylosing spondylitis.
Cytidine deaminase and lactoferrin in inflammatory synovial fluids. Indicators of local polymorphonuclear cell function?
In vivo inhibition of human neutrophil collagenase (MMP-8) activity during long-term combination therapy of doxycycline and non-steroidal anti-inflammatory drugs (NSAID) in acute reactive arthritis.
Recombinant Salmonella typhimurium outer membrane protein A is recognized by synovial fluid CD8 cells and stimulates synovial fluid mononuclear cells to produce interleukin (IL)-17/IL-23 in patients with reactive arthritis and undifferentiated spondyloarthropathy.
[Some proteins of acute phase of inflammation in differential diagnostics of rheumatoid arthritis]
[The criteria of differentiated diagnostics of early arthritis on the basis of analysis of serum hyaluronidase and deoxyribonuclease activity].
Arthritis, Rheumatoid
ANCA with specificity for lactoferrin in systemic lupus erythematosus (SLE).
Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.
Antineutrophil cytoplasmic antibodies against myeloperoxidase, proteinase 3, elastase, cathepsin G and lactoferrin in Japanese patients with rheumatoid arthritis.
Antineutrophil cytoplasmic antibodies in Bulgarian patients with rheumatoid arthritis: characterization and clinical associations.
Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in inflammatory disorders.
Association of the DNASE1L3 rs35677470 polymorphism with systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis: Structural biological insights.
Cytidine deaminase activity in synovial fluid of patients with rheumatoid arthritis: relation to lactoferrin, acidosis, and cartilage proteoglycan release.
Cytidine deaminase and lactoferrin in inflammatory synovial fluids. Indicators of local polymorphonuclear cell function?
Determination of metalloproteinases, plasminogen-activators and their inhibitors in the synovial fluids of patients with rheumatoid arthritis during chemical synoviorthesis.
DNA polymerase activity in rheumatoid synovial membranes.
DNase1 exon2 analysis in Tunisian patients with rheumatoid arthritis, systemic lupus erythematosus and Sjögren syndrome and healthy subjects.
Expression of lactoferrin on neutrophil granulocytes from synovial fluid and peripheral blood of patients with rheumatoid arthritis.
Increased levels of lactoferrin in synovial fluid but not in serum from patients with rheumatoid arthritis.
Increased plasma lactoferrin levels in leucocytapheresis therapy in patients with rheumatoid arthritis.
Influence of HumDN1 VNTR polymorphism on DNASE1 expression in systemic lupus erythematosus and rheumatoid arthritis.
Iron, lactoferrin and iron regulatory protein activity in the synovium; relative importance of iron loading and the inflammatory response.
Lactoferrin and lysozyme levels in synovial fluid: differential indices of articular inflammation and degradation.
Lactoferrin and the inflammatory response.
Lactoferrin in rheumatoid arthritis and systemic lupus erythematous.
Lactoferrin in synovial fluid.
Neutrophil-derived lactoferrin induces the inflammatory responses of rheumatoid arthritis synovial fibroblasts via Toll-like receptor 4.
Plasma lactoferrin and neutrophil elastase in rheumatoid arthritis and systemic lupus erythematosus.
Prevalence and clinical significance of anti-lactoferrin autoantibodies in inflammatory bowel diseases and primary sclerosing cholangitis.
Salivary Immunoglobulin Gamma-3 Chain C Is a Promising Noninvasive Biomarker for Systemic Lupus Erythematosus.
Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus.
Serum level of DNase1l3 in patients with dermatomyositis/polymyositis, systemic lupus erythematosus and rheumatoid arthritis, and its association with disease activity.
Serum lysozyme: a potential marker of monocyte/macrophage activity in rheumatoid arthritis.
Sialochemical markers of salivary gland involvement with Sjögren's syndrome secondary to rheumatoid arthritis and primary biliary cirrhosis.
Suppression of in vitro IgM rheumatoid factor production by diphtheria toxin interleukin 2 recombinant fusion protein (DAB 486IL-2) in patients with refractory rheumatoid arthritis.
The non-immune inflammatory response: serial changes in plasma iron, iron-binding capacity, lactoferrin, ferritin and C-reactive protein.
Two spatially distant epitopes of human lactoferrin.
[Correlation of DNase I in serum and synovial fluid with inflammatory activity in patients with rheumatoid arthritis].
[Dynamics of granulocyte proteins after lymphocytapheresis in patients with rheumatoid arthritis]
[Levels of the C 4 component of the complement, lactoferrin and leukocytic thermostabile alpha glycoprotein during the treatment of patients with systemic rheumatic diseases]
[Some proteins of acute phase of inflammation in differential diagnostics of rheumatoid arthritis]
[The criteria of differentiated diagnostics of early arthritis on the basis of analysis of serum hyaluronidase and deoxyribonuclease activity].
Ascorbic Acid Deficiency
[Activity of deoxyribonuclease during the development of ascorbic acid deficiency in guinea pigs]
[Influence of acute vitamin C deficiency on the activity of desoxyribonuclease I of the guinea pig]
Aspergillosis, Allergic Bronchopulmonary
A pulmonary exacerbation risk score among cystic fibrosis patients not receiving recommended care.
Asthenopia
[Dry eye syndrome of deficient lacrima production treated with the acupoint thread-embedding therapy: a randomized controlled trial].
Asthenozoospermia
Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia.
[Ejaculate microflora sensitivity to lactoferrin in chronic prostatitis]
Asthma
A deoxyribonuclease 1-like 3 genetic variant associates with asthma exacerbations.
A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma.
A sputum gene expression signature predicts oral corticosteroid response in asthma.
Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-induced asthma model.
Allergens Induce the Release of Lactoferrin by Neutrophils from Asthmatic Patients.
Expression of pulmonary lactoferrin in sudden-onset and slow-onset asthma with fatal outcome.
Immobilized lactoferrin is a stimulus for eosinophil activation.
Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment.
Iron-binding proteins in sputum of chronic bronchitis patients with Haemophilus influenzae infections.
Lactoferrin administration into the nostril alleviates murine allergic rhinitis and its mechanisms.
Lactoferrin and secretory IgA in the bronchoalveolar lavage fluid from patients with a stable asthma.
Lactoferrin decreases pollen antigen-induced allergic airway inflammation in a murine model of asthma.
Lactoferrin, a potent tryptase inhibitor, abolishes late-phase airway responses in allergic sheep.
Quartz crystal microbalance immunosensor for the detection of antibodies to double-stranded DNA.
Recombinant human deoxyribonuclease for the treatment of acute asthma in children.
Recombinant human deoxyribonuclease therapy improves airway resistance and reduces DNA extracellular traps in a murine acute asthma model.
Six gene and TH2 signature expression in endobronchial biopsies of participants with asthma.
Small-airways deposition of dornase alfa in children with asthma and persistent airway obstruction.
Stimulated salivary flow rate and composition in asthmatic and non-asthmatic adults.
Technology evaluation: rh lactoferrin, Agennix.
Use of recombinant human deoxyribonuclease for the treatment of acute asthma.
[The Churg-Strauss syndrome]
Astrocytoma
Cell-specific expression of the mouse glial fibrillary acidic protein gene: identification of the cis- and trans-acting promoter elements for astrocyte-specific expression.
Detection and quantitative analysis of human herpesvirus in pilocytic astrocytoma.
Immunohistochemical detection of lactoferrin in human astrocytomas and multiforme glioblastomas.
Tumour necrosis factor alpha and interleukin-1 beta induce specific subunits of NFKB to bind the HIV-1 enhancer: characterisation of transcription factors controlling human immunodeficiency virus type 1 gene expression in neural cells.
Asymptomatic Infections
Gene expression of factors related to the immune reaction in response to intramammary Escherichia coli lipopolysaccharide challenge.
The association between colicinogenicity and pathogenesis among uropathogenic isolates of Escherichia coli.
Ataxia
Diphtheria toxin mutant selectively kills cerebellar Purkinje neurons.
The Second Subunit of DNA Polymerase Delta Is Required for Genomic Stability and Epigenetic Regulation.
Ataxia Telangiectasia
DNA repair enzyme deficiency and in vitro complementation of the enzyme activity in cell-free extracts from ataxia telangiectasia fibroblasts.
DNA repair enzymes in ataxia telangiectasia and Bloom's syndrome fibroblasts.
Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers?
Atherosclerosis
Augmented neutrophil extracellular traps formation promotes atherosclerosis development in socially defeated apoE-/- mice.
Bone Marrow-Derived Smooth Muscle-Like Cells Are Infrequent in Advanced Primary Atherosclerotic Plaques but Promote Atherosclerosis.
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents.
Enteric lactoferrin attenuates the development of high-fat and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis in Microminipigs.
Functional polymorphisms in the LTF gene and risk of coronary artery stenosis.
Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis.
Lactoferrin Alleviates the Progression of Atherosclerosis in ApoE-/- Mice Fed with High-Fat/Cholesterol Diet Through Cholesterol Homeostasis.
Lactoferrin promotes bile acid metabolism and reduces hepatic cholesterol deposition by inhibiting the farnesoid X receptor (FXR)-mediated enterohepatic axis.
Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques.
Neutrophil Extracellular Traps (NETs) promote macrophage inflammation and impair atherosclerosis resolution in mice with diabetes.
[Heparin-binding epidermal growth factor (HB-EGF): myth or reality?]
Autoimmune Diseases
A biochemical and genetic study on all non-synonymous single nucleotide polymorphisms of the gene encoding human deoxyribonuclease I potentially relevant to autoimmunity.
A proposal of new ocular items in Sjögren's syndrome classification criteria.
An autosomal recessive DNASE1L3-related autoimmune disease with unusual clinical presentation mimicking systemic lupus erythematosus.
Antibodies to lactoferrin. A possible link between cow's milk intolerance and autoimmune disease.
Association of the DNASE1L3 rs35677470 polymorphism with systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis: Structural biological insights.
Autoimmune pancreatitis.
Caucasian-specific allele in non-synonymous single nucleotide polymorphisms of the gene encoding deoxyribonuclease I-like 3, potentially relevant to autoimmunity, produces an inactive enzyme.
Diagnostic Value of Serum DNASE1L3 in Hepatitis B Virus-Related Hepatocellular Carcinoma.
Effect of lactoferrin on the phagocytic activity of polymorphonuclear leucocytes isolated from blood of patients with autoimmune diseases and Staphylococcus aureus allergy.
Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment.
Electrostatic protein immobilization using charged polyacrylamide gels and cationic detergent microfluidic Western blotting.
Evaluation of all non-synonymous single nucleotide polymorphisms (SNPs) in the genes encoding human deoxyribonuclease I and I-like 3 as a functional SNP potentially implicated in autoimmunity.
Extracellular DNA: A Bridge to Cancer.
Functional Single Nucleotide Polymorphisms (SNPs) in the Genes Encoding the Human Deoxyribonuclease (DNase) Family Potentially Relevant to Autoimmunity.
Global genetic analysis of all single nucleotide polymorphisms in exons of the human deoxyribonuclease I-like 3 gene and their effect on its catalytic activity.
Hepatic and extrahepatic clearance of circulating human lactoferrin: an experimental study in rat.
Human tear protein analysis enabled by an alkaline microfluidic homogeneous immunoassay.
Lactoferrin in chronic pancreatitis.
Lactoferrin triggers in vitro proliferation of T cells of Lewis rats submitted to mycobacteria-induced adjuvant arthritis.
Mycobacteria and human autoimmune disease: direct evidence of cross-reactivity between human lactoferrin and the 65-kilodalton protein of tubercle and leprosy bacilli.
Serum Deoxyribonuclease 1-like 3 is a potential biomarker for diagnosis of ankylosing spondylitis.
Serum level of DNase1l3 in patients with dermatomyositis/polymyositis, systemic lupus erythematosus and rheumatoid arthritis, and its association with disease activity.
[Blood deoxyribonuclease activity in health and diseases]
Autoimmune Pancreatitis
Atypical manifestations of pancreatitis with autoimmune phenomenon in an adolescent female.
Autoimmune pancreatitis.
Experimental immune-mediated pancreatitis in neonatally thymectomized mice immunized with carbonic anhydrase II and lactoferrin.
Lactoferrin in chronic pancreatitis.
What are the useful biological and functional markers of early-stage chronic pancreatitis?
[Autoimmune pancreatitis with normal IgG4-Levels: 4 case reports and review of the literature]
Avian Leukosis
Characterization of endogenous RNA-directed DNA polymerase activity of reticuloendotheliosis viruses.
Chemical carcinogen-induced transplantable fibrosarcomas in histocompatible chickens. I. Incidence of tumor induction in normal and bursectomized chickens.
Marker rescue of endogenous cellular genetic information related to the avian leukosis virus gene encoding RNA-directed DNA polymerase.
Pheasant virus DNA polymerase is related to avian leukosis virus DNA polymerase at the active site.
Purification and properties of spleen necrosis virus DNA polymerase.
Radioimmunological comparison of the DNA polymerases of avian retroviruses.
Avitaminosis
[Deoxyribonuclease activity and testicular degeneration in various avitaminoses]
[INFLUENCE OF ACUTE AVITAMINOSIS C ON HEPATIC DESOXYRIBONUCLEASE ACTIVITY IN THE GUINEA PIG.]
Bacteremia
Acinetobacter baumannii can use multiple siderophores for iron acquisition, but only acinetobactin is required for virulence.
Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae.
Evaluation of serotypes 5 and 8 capsular polysaccharides in protection against Staphylococcus aureus in murine models of infection.
Impact of Streptococcus pneumoniae bacteremia and human immunodeficiency virus type 1 on oral mucosal immunity.
Investigational antimicrobial drugs for bloodstream infections.
Lactoferrin protects neonatal rats from gut-related systemic infection.
Overproduction of Outer Membrane Protein A by Acinetobacter baumannii as a Risk Factor for Nosocomial Pneumonia, Bacteremia, and Mortality Rate Increase.
Prediction of microbial infection and mortality in medical patients with fever: plasma procalcitonin, neutrophilic elastase-alpha1-antitrypsin, and lactoferrin compared with clinical variables.
Prophylactic effect of human lactoferrin against Streptococcus mutans bacteremia in lactoferrin knockout mice.
Protective effects of human lactoferrin during Aggregatibacter actinomycetemcomitans-induced bacteremia in lactoferrin-deficient mice.
Protective effects of lactoferrin in Escherichia coli-induced bacteremia in mice: relationship to reduced serum TNF alpha level and increased turnover of neutrophils.
Virulence-related genes in ColV plasmids of Escherichia coli isolated from human blood and intestines.
Bacterial Infections
Aae, an autotransporter involved in adhesion of Actinobacillus actinomycetemcomitans to epithelial cells.
Abnormal distribution of complex carbohydrates in neutrophils of a patient with lactoferrin deficiency.
Anti-Invasive Activity of Bovine Lactoferrin against Listeria monocytogenes.
Antimicrobial activity of bovine ?-lactoglobulin against mastitis-causing bacteria.
Apoptosis of Caco-2 intestinal cells invaded by Listeria monocytogenes: protective effect of lactoferrin.
Bovine lactoferrin interacts with cable pili of Burkholderia cenocepacia.
Clinical Trials of Lactoferrin in the Newborn: Effects on Infection and the Gut Microbiome.
Control mechanisms for producing antimicrobial factors in ruminant mammary gland.
Defence of mucous membranes by antibodies, receptor analogues and non-specific host factors.
Defending the homeland: microbiome molecules provide protection to their vertebrate hosts.
Detection of fungal infections using radiolabeled antifungal agents.
Elastase alpha 1-proteinase inhibitor and lactoferrin concentrations in endotracheal aspirates of ventilated newborns.
Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset.
Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation.
Lactoferrin and lysozyme in the intrahepatic bile duct of normal livers and hepatolithiasis. An immunohistochemical study.
Lactoferrin and the inflammatory response.
Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells.
Lactoferrin in relation to acute phase proteins in sera from newborn infants with severe infections.
Lactoferrin-enhanced anoikis: a defense against neonatal necrotizing enterocolitis.
Neutrophil and eosinophil granulocytes in bacterial infection: sequential studies of cellular and serum levels of granule proteins.
Neutrophilic granulocytes in acute bacterial infection. Sequential studies on lysozyme, myeloperoxidase and lactoferrin.
Outer membrane protein A (OmpA): a new player in shigella flexneri protrusion formation and inter-cellular spreading.
Plasma lactoferrin content: differential effect of steroid administration and infective illnesses: lack of effect of ambient temperature at which specimens are collected.
Probiotic Lactobacillus casei Expressing Human Lactoferrin Elevates Antibacterial Activity in the Gastrointestinal Tract.
Radiotracers for fungal infection imaging.
Recombinant outer membrane protein A induces a protective immune response against Escherichia coli infection in mice.
Relationship between milk lactoferrin and etiological agent in the mastitic bovine mammary gland.
Structure and functions of bacterial outer membrane protein A, a potential therapeutic target for bacterial infection.
Study on the polymorphism of bovine lactoferrin gene and its relationship with mastitis.
Surface functionalization of titanium substrates with Deoxyribonuclease I inhibit peri-implant bacterial infection.
The biosynthesis and biological function of diphthamide.
The utility of lactoferrin in differentiating parasitic from bacterial infections.
[Elastase-alpha 1-proteinase inhibitor complex (E alpha 1 PI) and lactoferrin plasma concentrations in viral and bacterial infections]
[Lactoferrin]
beta-Thalassemia
Detection of beta-thalassemia mutations in the Chinese using amplified DNA from dried blood specimens.
Blepharitis
Influence of topical anesthesia on tests diagnostic of blepharitis-associated dry eye syndrome.
Microbial and immunological investigations of chronic non-ulcerative blepharitis and meibomianitis.
Tear lactoferrin levels in chronic meibomitis associated with acne rosacea.
Blister
Dissociation of suction blister roof epidermis with trypsin and desoxyribonuclease into viable single cells.
Helicobacter pylori ATCC 43629/NCTC 11639 Outer Membrane Vesicles (OMVs) from Biofilm and Planktonic Phase Associated with Extracellular DNA (eDNA).
IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin.
The development of mucosal immunity in guinea pig middle ears.
Bloom Syndrome
Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals.
DNA repair enzymes in ataxia telangiectasia and Bloom's syndrome fibroblasts.
Enhanced deoxyribonuclease activity in human transformed cells and in Bloom's syndrome cells.
The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase ? Elongation.
Bluetongue
Cloning of the bluetongue virus L3 gene.
Bone Resorption
Bone Regeneration Is Promoted by Orally Administered Bovine Lactoferrin in a Rabbit Tibial Distraction Osteogenesis Model.
Effects of lactoferrin on bone resorption of midpalatal suture during rapid expansion in rats.
Histologic and histomorphometric evaluation of the effect of lactoferrin combined with anorganic bovine bone on healing of experimentally induced bony defects on rabbit calvaria.
Lactoferrin ameliorates aging-suppressed osteogenesis via IGF1 signaling.
Lactoferrin inhibits infection-related osteoclastogenesis without interrupting compressive force-related osteoclastogenesis.
Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo.
Lactoferrin promotes bone growth.
Lactoferrin: a biologically active molecule for bone regeneration.
The relationship of fetuin-A and lactoferrin with bone mass in elderly women.
Botulism
[On the detoxification function of iron uptake: animal experiment studies on the detoxification of botulism A, tetanus and diphtheria toxin by hemosiderin and reducing substances. I.]
Brain Abscess
Molecular diagnosis of Nocardia farcinica from a cerebral abscess.
The expansion of the microbiological spectrum of brain abscesses with use of multiple 16S ribosomal DNA sequencing.
Brain Death
[Decellularized human tissue engineering aortic valves conduit]
Brain Diseases
Localized cerebral energy failure in DNA polymerase gamma-associated encephalopathy syndromes.
Brain Edema
Targeting neutrophil extracellular traps enhanced tPA fibrinolysis for experimental intracerebral hemorrhage.
[Activity of lysosomal enzymes in rabbit brain during the development of edema]
Brain Injuries
Lactoferrin during lactation reduces lipopolysaccharide-induced brain injury.
Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage.
Protocol for the Lactoferrin Infant Feeding Trial (LIFT): a randomised trial of adding lactoferrin to the feeds of very-low birthweight babies prior to hospital discharge.
Brain Injuries, Traumatic
Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.
DNase I disinhibition is predominantly associated with actin hyperpolymerization after traumatic brain injury.
Fresh-frozen plasma resuscitation after traumatic brain injury and shock attenuates extracellular nucleosome levels and deoxyribonuclease 1 depletion.
Brain Ischemia
Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion.
Investigation and comparison of the protective activities of three functional proteins-lactoferrin, ?-lactalbumin, and ?-lactoglobulin-in cerebral ischemia reperfusion injury.
Modulation activity of heat-treated and untreated lactoferrin on the TLR-4 pathway in anoxia cell model and cerebral ischemia reperfusion mouse model.
Brain Neoplasms
Dual-Targeting Lactoferrin-Conjugated Polymerized Magnetic Polydiacetylene-Assembled Nanocarriers with Self-Responsive Fluorescence/Magnetic Resonance Imaging for In Vivo Brain Tumor Therapy.
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells.
Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors.
Gene expression profiles in human nasal polyp tissues studied by means of DNA microarray.
Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer.
Lactoferrin induced neuronal differentiation: A boon for brain tumours.
Lactoferrin, lysozyme, and beta 2-microglobulin levels in cerebrospinal fluid: differential indices of CNS inflammation.
Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors.
Breast Neoplasms
"Iron-saturated" bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice.
A comparison of spreading and motility behaviour of 8701-BC breast carcinoma cells on type I, I-trimer and type V collagen substrata. Evidence for a permissive effect of type I-trimer collagen on cell locomotion.
A strong intronic enhancer element of the EGFR gene is preferentially active in high EGFR expressing breast cancer cells.
Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells.
An antibody-toxin conjugate directed against a human mammary cancer antigen.
Analysis of human breast cancer nuclear proteins binding to the promoter elements of the c-myc gene.
Antigenic relatedness of the DNA polymerase of human breast cancer particles to the enzyme of the Mason-Pfizer monkey virus.
Binding of an ETS-related protein within the DNase I hypersensitive site of the HER2/neu promoter in human breast cancer cells.
Biodegradable Eri silk nanoparticles as a delivery vehicle for bovine lactoferrin against MDA-MB-231 and MCF-7 breast cancer cells.
Bovine lactoferrin induces cell cycle arrest and inhibits mTOR signaling in breast cancer cells.
Chromatin structure of the EGFR gene suggests a role for intron 1 sequences in its regulation in breast cancer cells.
Chromatin structure of the regulatory regions of pS2 and cathepsin D genes in hormone-dependent and -independent breast cancer cell lines.
Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
Co-assembled Ca2+ Alginate-Sulfate Nanoparticles for Intracellular Plasmid DNA Delivery.
Correction to: Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer.
Correlation between serum and tissue deoxyribonuclease levels in breast cancer patients.
Cytotoxicity and specificity of directed toxins composed of diphtheria toxin and the EGF-like domain of heregulin beta1.
Detection and isolation of a new DNA polymerase from human breast tumor cell line HBT-3 by (dT)12-18-cellulose chromatography.
Detection of exon polymorphisms in the human lactoferrin gene.
Development of a novel small antibody that retains specificity for tumor targeting.
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.
Discriminating a Single Nucleotide Difference for Enhanced miRNA Detection Using Tunable Graphene and Oligonucleotide Nanodevices.
Distribution of ferritin, transferrin and lactoferrin in breast carcinoma tissue.
DNA polymerase ? deficiency is linked to aggressive breast cancer: A comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts.
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
Effect of estrogen receptor ? binding on functional DNA methylation in breast cancer.
Effects of adenovirus vectors mediated human lactoferrin cDNA on mice bearing EMT6 breast carcinoma.
Effects of estrogen and antiestrogen on DNA polymerase in human breast cancer.
Evaluation of Antioxidant Intakes in Relation to Inflammatory Markers Expression Within the Normal Breast Tissue of Breast Cancer Patients.
Evaluation of serum alkaline DNase activity in treatment monitoring of head and neck cancer patients.
Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer.
Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe.
Gene regulation studies of aromatase expression in breast cancer and adipose stromal cells.
Growth differentiation factor-15 and lactoferrin immuno-expression in breast cancer: relationship with body iron-status and survival outcome.
Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ?.
Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer.
Influence of exogenous lactoferrin on the oxidant/antioxidant balance and molecular profile of hormone receptor-positive and -negative human breast cancer cells in vitro.
Inhibition of deoxyribonuclease I by actin is to protect cells from premature cell death.
Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer.
Internalization of CD239 highly expressed in breast cancer cells: a potential antigen for antibody-drug conjugates.
Investigation and comparison of the anti-tumor activities of lactoferrin, ?-lactalbumin, and ?-lactoglobulin in A549, HT29, HepG2, and MDA231-LM2 tumor models.
Iron-free and iron-saturated bovine lactoferrin inhibit survivin expression and differentially modulate apoptosis in breast cancer.
Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers?
Isolation of a lactoferrin cDNA clone and its expression in human breast cancer.
Lactoferrin expression in breast cancer in relation to biologic properties of tumors and clinical features of disease.
Lactoferrin expression in human breast cancer.
Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase.
Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes.
Localization of lactoferrin and nonspecific cross-reacting antigen in human breast carcinomas. An immunohistochemical study using the avidin-biotin-peroxidase complex method.
Modifying effects of lactoferrin in vitro on molecular phenotype of human breast cancer cells.
Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as efficient Notch-1 siRNA carrier for targeted killing of breast cancer.
Multimodal iron oxide (Fe3O4)-saturated lactoferrin nanocapsules as nanotheranostics for real-time imaging and breast cancer therapy of claudin-low, triple-negative (ER(-)/PR(-)/HER2(-)).
MZF-1 and DbpA interact with DNase I hypersensitive sites that correlate with expression of the human MUC1 mucin gene.
Novel DNase I hypersensitive sites in the 3'-flanking region of the human c-myc gene.
Oral administration of iron-saturated bovine lactoferrin-loaded ceramic nanocapsules for breast cancer therapy and influence on iron and calcium metabolism.
Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase ? and a de novo DNA Methyltransferase.
Polymorphism and altered methylation of the lactoferrin gene in normal leukocytes, leukemic cells, and breast cancer.
Potent in vitro antitumor activity of B-subunit of Shiga toxin conjugated to the diphtheria toxin against breast cancer.
Prognostic significance of immunohistochemical parameters in breast carcinomas.
Protective antitumor immunity induced by tumor cell lysates conjugated with diphtheria toxin and adjuvant epitope in mouse breast tumor models.
Purification and characterization of the DNA polymerase of human breast cancer particles.
Radio-immuno assay of lactoferrin in blood plasma of breast cancer patients, lactating and normal women; prevention of false high levels caused by leakage from neutrophile leucocytes in vitro.
Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells.
Recombination adenovirus-mediated human lactoferrin cDNA inhibits the growth of human MCF-7 breast cancer cells.
Regulation of vimentin gene transcription in human breast cancer cell lines.
Relative value of oestrogen receptor assay, lactoferrin content, and glucose-6-phosphate dehydrogenase activity as prognostic indicators in primary breast cancer.
Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis.
Role of heparan sulphate proteoglycans in the regulation of human lactoferrin binding and activity in the MDA-MB-231 breast cancer cell line.
Role of sialic acid and alkaline DNase in breast cancer.
SILAC-based proteomic profiling of the human MDA-MB-231 metastatic breast cancer cell line in response to the two antitumoral lactoferrin isoforms: the secreted lactoferrin and the intracellular delta-lactoferrin.
SIRT1 promotes proliferation, migration, and invasion of breast cancer cell line MCF-7 by upregulating DNA polymerase delta1 (POLD1).
Synthesis of lactoferrin mesoporous silica nanoparticles for pemetrexed/ellagic acid synergistic breast cancer therapy.
Synthesis of Pyrazolone Derivatives and Their Nanometer Ag(I) Complexes and Physicochemical, DNA Binding, Antitumor, and Theoretical Implementations.
Tear Lipocalin and Lipocalin-Interacting Membrane Receptor.
The effect of bovine milk lactoferrin on human breast cancer cell lines.
Theranostic multimodular potential of zinc-doped ferrite-saturated metal-binding protein-loaded novel nanocapsules in cancers.
Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene.
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen.
Tumor Lymphatic Function Regulates Tumor Inflammatory and Immunosuppressive Microenvironments.
Use of the Rad51 promoter for targeted anti-cancer therapy.
[Immunohistochemistry of alpha-lactalbumin, lactoferrin and trans- ferrin receptor in invasive breast carcinomas with regard to tumor grading, estrogen receptor status and tumor staging]
Bronchial Diseases
[Aerosol therapy with desoxyribonuclease in chronic bronchial diseases.]
Bronchial Spasm
Bronchospasm after inhalation of pancreatic dornase.
Bronchiectasis
Nebulised dornase alpha: adherence in adults with cystic fibrosis.
Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I. rhDNase Study Group.
Bronchiolitis
DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis.
Efficacy of recombinant human deoxyribonuclease I in the hospital management of respiratory syncytial virus bronchiolitis.
Management of bronchiolitis.
Randomized Controlled Trial of Bovine Lactoferrin for Prevention of Sepsis and Neurodevelopment Impairment in Infants Weighing Less Than 2000 Grams.
Recombinant human deoxyribonuclease in infants with respiratory syncytial virus bronchiolitis.
Bronchiolitis, Viral
Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months.
Bronchitis
Deoxyribonuclease in the treatment of purulent bronchitis.
Human Deoxyribonuclease (rhDNase) Nebulization as an Alternative Treatment for Refractory Plastic Bronchitis After Fontan Surgery.
Studies of bronchial secretion. The influence of inflammatory response and bacterial infection.
[Immunoglobulins, lactoferrin and the secretor state and their relationship to spastic bronchitis in the infant and small child]
Bronchitis, Chronic
Human lactoferrin receptor activity in non-encapsulated Haemophilus influenzae.
Iron-binding proteins in sputum of chronic bronchitis patients with Haemophilus influenzae infections.
Lower respiratory tract lactoferrin and lysozyme arise primarily in the airways and are elevated in association with chronic bronchitis.
Lysozyme and lactoferrin in sputum from patients with chronic obstructive lung disease.
Studies of bronchial secretion. The influence of inflammatory response and bacterial infection.
[Clinical significance of lysozyme and lactoferrin in chronic bronchitis patients]
Bronchopulmonary Dysplasia
Dornase alfa in premature infants with severe respiratory distress and early bronchopulmonary dysplasia.
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
Lactoferrin and lysozyme deficiency in airway secretions: association with the development of bronchopulmonary dysplasia.
Lactoferrin Supplementation to Prevent Late-Onset Sepsis in Preterm Infants: A Meta-Analysis.
Summary Protocol for a Multi-Centre Randomised Controlled Trial of Enteral Lactoferrin Supplementation in Newborn Very Preterm Infants (ELFIN).
Burkitt Lymphoma
Cellular and Epstein-Barr virus specific DNA polymerases in virus-producing Burkitt's lymphoma cell lines.
Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma.
Chromatin structure of transcriptionally active and inactive human c-myc alleles.
Comparison of DNA polymerase activities from an American Burkitt's lymphoma cell line and EBV producer and nonproducer cells.
Demonstration of lactoferrin in tumor tissue from two patients with positive gallium scans.
Induction of cellular DNA polymerases in a Burkitt lymphoma-derived cell line by treatment with 5-iododeoxyuridine.
Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP.
Isolation of a herpesvirus-specific DNA polymerase from tissues of an American patient with Burkitt lymphoma.
Caliciviridae Infections
Antiviral Effects of Bovine Lactoferrin on Human Norovirus.
Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?
The protective effects of lactoferrin against murine norovirus infection through inhibition of both viral attachment and replication.
Campylobacter Infections
To culture or not to culture: fecal lactoferrin screening for inflammatory bacterial diarrhea.
Candidemia
Investigational antimicrobial drugs for bloodstream infections.
Candidiasis
Conditions influencing the in vitro antifungal activity of lactoferrin combined with antimycotics against clinical isolates of Candida. Impact on the development of buccal preparations of lactoferrin.
Design and fungicidal activity of mucoadhesive lactoferrin tablets for the treatment of oropharyngeal candidosis.
Inhibition of growth of Candida albicans by iron-unsaturated lactoferrin: relation to host-defense mechanisms in chronic mucocutaneous candidiasis.
Lactoferrin peptide increases the survival of Candida albicans-inoculated mice by upregulating neutrophil and macrophage functions, especially in combination with amphotericin B and granulocyte-macrophage colony-stimulating factor.
Lactoferrin, chitosan and Melaleuca alternifolia-natural products that show promise in candidiasis treatment.
New sensitive method for the measurement of lysozyme and lactoferrin to explore mucosal innate immunity. Part II: time-resolved immunofluorometric assay used in HIV patients with oral candidiasis.
Oral lactoferrin protects against experimental candidiasis in mice.
Potential usefulness of bovine lactoferrrin for adjunctive immunotherapy for mucosal Candida infections.
The effects of human lactoferrin in experimentally induced systemic candidiasis.
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.
[Molecular pathogenesis of oral candidiasis (candidosis)]
[Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis]
Candidiasis, Chronic Mucocutaneous
Inhibition of growth of Candida albicans by iron-unsaturated lactoferrin: relation to host-defense mechanisms in chronic mucocutaneous candidiasis.
Candidiasis, Invasive
Synergistic Antifungal Effect of Lactoferrin with Azole Antifungals against Candida albicans and a Proposal for a New Treatment Method for Invasive Candidiasis.
Candidiasis, Oral
Complete response of severe, refractory oral candidiasis to mouthwash containing lactoferrin and lysozyme.
Conditions influencing the in vitro antifungal activity of lactoferrin combined with antimycotics against clinical isolates of Candida. Impact on the development of buccal preparations of lactoferrin.
Effect of orally administered bovine lactoferrin on the immune response in the oral candidiasis murine model.
New sensitive method for the measurement of lysozyme and lactoferrin to explore mucosal innate immunity. Part II: time-resolved immunofluorometric assay used in HIV patients with oral candidiasis.
Nonspecific secretory immunity in HIV-infected patients with oral candidiasis.
Oral lactoferrin treatment of experimental oral candidiasis in mice.
The potential management of oral candidiasis using anti-biofilm therapies.
[Development of murine experimental model for candidiasis and its application]
Candidiasis, Vulvovaginal
Randomised clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment.
[Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis]
Carcinogenesis
'Iron-saturated' lactoferrin is a potent natural adjuvant for augmenting cancer chemotherapy.
A simple but profound mutation in mouse DNA polymerase ? drives tumorigenesis.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine.
Antiproliferative and apoptosis inducing effect of lactoferrin and black tea polyphenol combination on hamster buccal pouch carcinogenesis.
Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies.
Cancer prevention by bovine lactoferrin: from animal studies to human trial.
Cancer progression mediated by horizontal gene transfer in an in vivo model.
Chemopreventive effect of bovine lactoferrin on 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats.
Chemopreventive effects of bovine lactoferrin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis.
Combination chemoprevention of hamster buccal pouch carcinogenesis by bovine milk lactoferrin and black tea polyphenols.
Discrimination and evaluation of lactoferrin and delta-lactoferrin gene expression levels in cancer cells and under inflammatory stimuli using TaqMan real-time PCR.
Dissecting the Functional Significance of DNA Polymerase Mutations in Cancer.
DNA polymerase ? mutational signatures are found in a variety of different types of cancer.
DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination.
DNA polymerases and cancer.
Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.
Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer.
Effect of N-methyl-N'-nitro-N-nitrosoguanidine on DNA polymerases alpha and beta in vitro.
Effects of lactoferrin, soya germ and polyamine on 2-amino-1-methyl-6- phenylimidazo[4,5-b]-pyridine(PhIP)- induced breast carcinogenesis in rats.
Evaluation of the Effect of Blackcurrant Products on Gut Microbiota and on Markers of Risk for Colon Cancer in Humans.
Evidence of finely tuned expression of DNA polymerase beta in vivo using transgenic mice.
Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer.
Folate deficiency provides protection against colon carcinogenesis in DNA polymerase {beta} haploinsufficient mice.
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.
Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer.
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta.
Immunoexpression of lactoferrin in triple-negative breast cancer patients: A proposal to select a less aggressive subgroup.
In vitro antioxidative potential of lactoferrin and black tea polyphenols and protective effects in vivo on carcinogen activation, DNA damage, proliferation, invasion, and angiogenesis during experimental oral carcinogenesis.
Inhibition of azoxymethane initiated colon tumor and aberrant crypt foci development by bovine lactoferrin administration in F344 rats.
Inhibition of azoxymethane-initiated colon tumor by bovine lactoferrin administration in F344 rats.
Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine.
Inhibitory effects of bovine lactoferrin on intestinal polyposis in the Apc(Min) mouse.
Involvement of DNA polymerase ? overexpression in the malignant transformation induced by benzo[a]pyrene.
Lack of Chronic Oral Toxicity of Chemopreventive Bovine Lactoferrin in F344/DuCrj Rats.
Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis.
Lactoferrin enhances Fas expression and apoptosis in the colon mucosa of azoxymethane-treated rats.
Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat.
Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
Mechanisms of metal carcinogenesis.
Mechanixm of Carcinogenesis By RNA Tumor Viruses, I. An RNA-Dependent DNA Polymerase In Murine Sarcoma Viruses.
Milk and dairy products in cancer prevention: focus on bovine lactoferrin.
Milk Components as Cancer Chemopreventive Agents.
Mitotic Arrest-Deficient Protein 2B Overexpressed in Lung Cancer Promotes Proliferation, EMT, and Metastasis.
Modulation of xenobiotic-metabolizing enzymes and redox status during chemoprevention of hamster buccal carcinogenesis by bovine lactoferrin.
Mutation at the Polymerase Active Site of Mouse DNA Polymerase {delta} Increases Genomic Instability and Accelerates Tumorigenesis.
Neoplastic transformation of the endocervix associated with downregulation of lactoferrin expression.
NOXIN as a cofactor of DNA polymerase-primase complex could promote hepatocellular carcinoma.
Nutritional roles of lactoferrin.
Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis.
Orally administered bovine lactoferrin induces caspase-1 and interleukin-18 in the mouse intestinal mucosa: a possible explanation for inhibition of carcinogenesis and metastasis.
Platelet DNA polymerase levels in CML: implications for oncogenesis.
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia.
Pol? O-GlcNAcylation governs genome integrity during translesion DNA synthesis.
Possible chemopreventive effects of bovine lactoferrin on esophagus and lung carcinogenesis in the rat.
Post-initiation chemopreventive effects of dietary bovine lactoferrin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in female A/J mice.
Prevention of carcinogenesis and cancer metastasis by bovine lactoferrin.
Prevention of colon carcinogenesis and carcinoma metastasis by orally administered bovine lactoferrin in animals.
Recent advances in metal carcinogenesis.
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
RNA-splicing factor SART3 regulates translesion DNA synthesis.
Role of Lactoferrin in the Carcinogenesis of Triple-Negative Breast Cancer.
Role of Lgr5-positive cells in colorectal cancer.
Sequential changes in DNA polymerases alpha and beta during diethylnitrosamine-induced carcinogenesis.
Spontaneous Polyploids and Antimutators Compete During the Evolution of Saccharomyces cerevisiae Mutator Cells.
The H19 endodermal enhancer is required for Igf2 activation and tumor formation in experimental liver carcinogenesis.
Transferrin in normal and neoplastic endocervical tissues: distribution and receptor expression.
Two polymorphic mutations in promoter region of DNA polymerase ? in relatively higher percentage of thymic hyperplasia patients.
Validity of HB-EGF as Target for Human Neuroblastoma Therapy.
[Chemopreventive effects of 5-fluorouracil and lactoferrin on goldfish intestinal carcinogenesis induced by 1,2-dimethylhydrazine].
[Interaction between lysosomes and cell nucleus during diethylnitrosamine-induced carcinogenesis. I. Changes in subcellular distribution of the lysosomal enzymes acid deoxyribonuclease and beta-galactosidase during acute intoxication by diethylnitrosamine]
[Minisatellite instability induced by okadaic acid]
[Neutral cytoplasmatic deoxyribonuclease of the rat liver and spleen in carcinogenesis]
[Neutral DNAse activity in rat tissues in radiation carcinogenesis]
[Transcriptional activation study of transforming gene Tx-related human nasopharyngeal carcinoma]
Carcinoma
A 17S multiprotein form of murine cell DNA polymerase mediates polyomavirus DNA replication in vitro.
A non-invasive QPCR method monitoring DNA based therapy of bladder cancer patients.
A novel combined conjugate vaccine: enhanced immunogenicity of bFGF with CRM197 as a carrier protein.
Actin polymerisation in Walker 256 carcinoma cells from solid or ascitic tumours.
Action of deoxyribonuclease and ribonuclease on the growth of Ehrlich ascites carcinoma in mice.
Aerosolized BC-819 inhibits primary but not secondary lung cancer growth.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
An immunohistochemical study of the distribution of lysozyme, lactoferrin, alpha 1-antitrypsin and alpha 1-antichymotrypsin in salivary adenoid cystic carcinoma.
Angiosarcoma Arising from the Tongue of an 11-Year-Old Girl with Xeroderma Pigmentosum.
Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine-treated male albino mice.
Apical-to-basolateral transepithelial transport of human lactoferrin in the intestinal cell line HT-29cl.19A.
Association of DNase I phenotype 2 with colorectal carcinoma risk in Japanese populations.
Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition in oral squamous cell carcinoma.
Cancer progression mediated by horizontal gene transfer in an in vivo model.
Cd11b(+) myeloid cells support hepatic metastasis through down-regulation of angiopoietin-like 7 in cancer cells.
Cell kinetics in ovarian cancer. Relationship to clinicopathologic features, responsiveness to chemotherapy, and survival.
Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells.
Changes in the topological expression of markers of differentiation and apoptosis in defined stages of human cervical dysplasia and carcinoma.
Clear cell carcinoma of salivary glands: immunohistochemical evaluation of clear tumor cells.
Comparison of Proliferative Effect of Human Lactoferrin and Its Proteolytic Peptide on Normal and Transformed Epithelial Cells.
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Cross-reacting material 197 reverses the resistance to paclitaxel in paclitaxel-resistant human ovarian cancer.
Cross-reacting material 197, a heparin-binding EGF-like growth factor inhibitor, reverses the chemoresistance in human cisplatin-resistant ovarian cancer.
Cytotoxic effect of diphtheria toxin used alone or in combination with other agents on human renal cell carcinoma cell lines.
Detection of HPV infection in head and neck squamous cell carcinoma: a practical proposal.
Detection of proliferative cells in dysplasia, carcinoma in situ, and invasive carcinoma of the uterine cervix by monoclonal antibody against DNA polymerase alpha.
Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Diagnostic value of lactoferrin analysis in pleural effusions.
Diphtheria toxin effects on brain-tumor xenografts. Implications for protein-based brain-tumor chemotherapy.
DNA polymerase ? mutations and survival of patients with esophageal squamous cell carcinoma in Linzhou City, China.
DNA polymerase ? promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.
DNA polymerase activities and nucleic acid components of virions isolated from a spontaneous mammary carcinoma from a rhesus monkey.
DNA polymerase and DNA synthesis in mammary carcinoma cells.
DNase I sensitivity of nuclear DNA measured by flow cytometry.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer.
E6/E7 expression of human papillomavirus types in cutaneous squamous cell dysplasia and carcinoma in immunosuppressed organ transplant recipients.
EFFECT OF BACTERIAL DEOXYRIBONUCLEASE ON EHRLICH'S ASCITES CARCINOMA CELLS IN VITRO.
Effect of insulin on DNA synthesis and DNA polymerase activity in organ culture of rat mammary carcinoma, and the inflence of insulin pretreatment and of alloxan diabetes.
Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1.
Effect of mitoxantrone on DNA polymerase of Ehrlich ascites carcinoma cells.
Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities.
Electrogene transfer of an Epstein-Barr virus-based plasmid replicon vector containing the diphtheria toxin A gene suppresses mammary carcinoma growth in SCID mice.
Enhanced inhibition of murine prostatic carcinoma growth by immunization with or administration of viable human umbilical vein endothelial cells and CRM197.
Enhancement of silencing DNA polymerase ? on the radiotherapeutic sensitivity of human esophageal carcinoma cell lines.
Enhancement of X-ray toxicity in squamous cell carcinoma cell lines by DNA polymerase inhibitors.
Entry of protein toxins in polarized epithelial cells.
Exon 8-9 mutations of DNA polymerase ? in ovarian carcinoma patients from Haldia, India.
Extremely high prevalence of DNASE1*1 allele in African populations.
Generation of anti-tumour immune response using dendritic cells pulsed with carbonic anhydrase IX-Acinetobacter baumannii outer membrane protein A fusion proteins against renal cell carcinoma.
HAX-1 promotes the chemoresistance, invasion, and tumorigenicity of esophageal squamous carcinoma cells.
Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.
Histogenesis of anaplastic carcinomas of the thyroid, giant cell variety: immunocytochemical investigation.
Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors.
Identification of a deoxyribonuclease activity in the nuclei of the cervical carcinoma HeLa.
Identification of the primary site of metastatic adenocarcinoma in serous effusions. Value of an immunocytochemical panel added to the clinical arsenal.
Identification of unprecedented anticancer properties of high molecular weight biomacromolecular complex containing bovine lactoferrin (HMW-bLf).
Immunocytochemical detection of lactoferrin in human gastric carcinomas and adenomas.
Immunoexpression of lactoferrin in bone metastases and corresponding primary carcinomas.
Immunoexpression of lactoferrin in human sporadic renal cell carcinomas.
Immunohistochemical demonstration of lactoferrin in follicular adenomas and thyroid carcinomas.
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland.
Immunolocalization of lactoferrin in surgically resected pigmented skin lesions.
Immunostimulatory Activity of Dendritic cells pulsed with carbonic anhydrase IX and Acinetobacter baumannii outer membrane protein A.
Immunotoxins in cancer therapy: Review and update.
Impact of ERCC1, XPF and DNA Polymerase ? Expression on Platinum Response in Patient-Derived Ovarian Cancer Xenografts.
Improved survival of patients with hypermutation in uterine serous carcinoma.
In vitro antioxidative potential of lactoferrin and black tea polyphenols and protective effects in vivo on carcinogen activation, DNA damage, proliferation, invasion, and angiogenesis during experimental oral carcinogenesis.
In vitro evaluation of the anticancer effect of lactoferrin and tea polyphenol combination on oral carcinoma cells.
In vitro synthesis of immunoglobulins and other proteins by dysplastic and neoplastic human mammary tissues.
Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences.
Inhibitory effects of bovine lactoferrin on colon carcinoma 26 lung metastasis in mice.
Inhibitory effects of human lactoferrin on U14 cervical carcinoma through upregulation of the immune response.
Initial experiences with serum alkaline DNase activity in monitoring the effects of therapy for carcinoma of the uterine cervix.
Integration site of human papillomavirus type-18 DNA in chromosome band 8q22.1 of C4-I cervical carcinoma: DNase I hypersensitivity and methylation of cellular flanking sequences.
Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase ? and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma.
Interaction between p12CDK2AP1 and a novel unnamed protein product inhibits cell proliferation by regulating the cell cycle.
Interaction of lactoferrin with mononuclear and colon carcinoma cells.
Investigation of ornamental fish entering the EU for the presence of ranaviruses.
Iron-binding proteins in thyroid tumours. An immunocytochemical study.
Lactoferrin and albumin in human pancreatic juice: a valuable test for diagnosis of pancreatic diseases.
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.
Lactoferrin in benign hypertrophy and carcinomas of the prostatic gland.
Lactoferrin in thyroid lesions: immunoreactivity in fine needle aspiration biopsy samples.
Lactoferrin inhibits growth of malignant tumors of the head and neck.
Large cell carcinoma of the lung. Prognostic implications of histopathologic and immunohistochemical subtyping.
Long-term cultivation of human mammary carcionoma: proliferation and differential biochemical properties of the cultured cells.
Malignant oncocytoma of the lacrimal sac: ultrastructure and immunocytochemistry.
Measurement of deoxyuridine triphosphate and thymidine triphosphate in the extracts of thymidylate synthase-inhibited cells using a modified DNA polymerase assay.
MiR-499 Enhances the Cisplatin Sensitivity of Esophageal Carcinoma Cell Lines by Targeting DNA Polymerase ?.
Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma.
Mutation analysis of 8p genes POLB and PPP2CB in bladder cancer.
MZF-1 and DbpA interact with DNase I hypersensitive sites that correlate with expression of the human MUC1 mucin gene.
On the alleged high sensitivity of mouse Ehrlich-Lettre ascites tumor cells to diphtheria toxin.
Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy.
Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo.
Orally administered lactoferrin exerts an antimetastatic effect and enhances production of IL-18 in the intestinal epithelium.
Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo.
Phenotype 2 of deoxyribonuclease I may be used as a risk factor for gastric carcinoma.
Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of ESCC.
Possible chemopreventive effects of bovine lactoferrin on esophagus and lung carcinogenesis in the rat.
Prevention of colon carcinogenesis and carcinoma metastasis by orally administered bovine lactoferrin in animals.
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
Quantitative estimation of tumor metastasis by measurement of DNA polymerase activity.
Radioimmunoassay of lactoferrin in pancreatic juice as a test for pancreatic diseases.
Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Reduced inhibition of Candida albicans adhesion by saliva from patients receiving oral cancer therapy.
REV3L, the catalytic subunit of DNA polymerase ?, is involved in the progression and chemoresistance of esophageal squamous cell carcinoma.
Serum alkaline deoxyribonuclease in oral cancer and premalignant lesions.
TdT expression in normal and neoplastic sebaceous cells.
The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions.
The anti-tumor effect of cross-reacting material 197, an inhibitor of heparin-binding EGF-like growth factor, in human resistant ovarian cancer.
The binding of lactoferrin to glycosaminoglycans on enterocyte-like HT29-18-C1 cells is mediated through basic residues located in the N-terminus.
The cytotoxic effects of human neutrophil peptide-1 (HNP1) and lactoferrin on oral squamous cell carcinoma (OSCC) in vitro.
The effect of cyclic nucleotides on DNA polymerase, thymidylate synthetase, thymidine kinase and deoxynucleoside levels of Waler carcinoma.
The effect of DNA polymerase inhibitors on the cytotoxicity of cisplatin in human ovarian carcinoma cells.
The geometry of diphtheria toxoid CRM197 channel assessed by thiazolium salts and nonelectrolytes.
The K167I variant of DNA polymerase ? that is found in Esophageal Carcinoma patients impairs polymerase activity and BER.
The relationship of lactoferrin to the anemia of renal cell carcinoma.
Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene.
Tumor antigens in neoplasms of the human parotid gland.
Tumor markers in parotid gland carcinomas: immunohistochemical investigations.
Tumoricidal Activity of RNase A and DNase I.
Ultrastructural and immunohistochemical characteristics of lipid-rich carcinoma of the breast.
Urine Lactoferrin as a Potential Biomarker Reflecting the Degree of Malignancy in Urothelial Carcinoma of the Bladder.
Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations.
[A tumor-associated antigen of cervical cancer]
[Action of ribonuclease and desoxyribonuclease on the incorporation of L-glutamic acid U-C-14 and methionine S-35 in tumor cells of Ehrlich's ascites carcinoma]
[Clinicopathological study of salivary gland adenocarcinomas]
[CONTRIBUTIONS TO THE STUDY OF THE CYTOMORPHOLOGICAL CHANGES IN EHRLICH'S ASCITES CARCINOMA UNDER THE INFLUENCE OF RIBONUCLEASE AND DESOXYRIBONUCLEASE.]
[Effect of bacterial desoxyribonuclease on Ehrlich ascites carcinoma in mice.]
[Effects and molecular mechanisms of the biological action of weak and extremely weak magnetic fields].
[Iron and iron-binding proteins in the differential diagnosis of pleural effusion]
[Mechanism of p53 gene mutation in the development of urologic cancer]
[Molecular mechanisms of biological action of low magnetic fields. I. Stability of chromatin from Ehrlich ascite carcinoma and mouse brain cells to the treatment of DNase 1 under combined action of low constant and alternating low-frequency magnetic fields adjusted to the cyclotron resonance of ions of polar amino acids]
[Pharmacokinetics of human milk lactoferrin in intact mice and tumor-carrying animals]
[Possible value of variations in the serum alkaline DNAse activity in the prognosis of cancers of the upper respiratory-digestive tract treated by chemotherapy]
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
[Relationship between tumor cell proliferating activity and biological behavior, prognosis in laryngeal carcinoma]
[Reverse of the resistance to paclitaxel of the heparin binding-epidermal growth factor-like growth factor inhibitor in ovarian cancer].
Carcinoma in Situ
Detection of proliferative cells in dysplasia, carcinoma in situ, and invasive carcinoma of the uterine cervix by monoclonal antibody against DNA polymerase alpha.
Carcinoma, Acinar Cell
Immunocytochemistry of acinic cell carcinomas and mixed tumors of salivary glands.
Malignant oncocytoma of the lacrimal sac: ultrastructure and immunocytochemistry.
[Use of tumor markers in the diagnosis of salivary gland tumors]
Carcinoma, Adenoid Cystic
An immunohistochemical study of the distribution of lysozyme, lactoferrin, alpha 1-antitrypsin and alpha 1-antichymotrypsin in salivary adenoid cystic carcinoma.
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.
Carcinoma, Basal Cell
Angiosarcoma Arising from the Tongue of an 11-Year-Old Girl with Xeroderma Pigmentosum.
E6/E7 expression of human papillomavirus types in cutaneous squamous cell dysplasia and carcinoma in immunosuppressed organ transplant recipients.
Immunolocalization of lactoferrin in surgically resected pigmented skin lesions.
Carcinoma, Ductal
Localization of lactoferrin and nonspecific cross-reacting antigen in human breast carcinomas. An immunohistochemical study using the avidin-biotin-peroxidase complex method.
Carcinoma, Ehrlich Tumor
A DNA polymerase from Ehrlich ascites tumor cells with preference for native DNA.
Differential DNase I sensitivity of the two complementary nucleosomal DNA strands in cycloheximide-treated Ehrlich ascites tumor cells.
DNA polymerase in nuceoli isolated from Ehrlich ascites tumor cells.
Effect of diphtheria toxin on lysosome activity in leukocytes and Ehrlich ascites tumor cells.
Effects of iron-binding proteins on in vitro uptake of 67Ga-citrate by tumor cells.
Entry of diphtheria toxin into cells: possible existence of cellular factor(s) for entry of diphtheria toxin into cells was studied in somatic cell hybrids and hybrid toxins.
Fractionation of native and reconstituted chromatin by digesting with deoxyribonuclease ii.
Mouse DNA polymerase accompanied by a novel RNA polymerase activity: purification and partial characterization.
Polyacrylamide gel electrophoresis of DNA polymerase from Ehrlich ascites tumor cells and recovery of active enzyme.
Studies on ehrlich ascites tumour cells: DNA synthesis, and template activity of chromatin for DNA polymerase.
Template requirements of a DNA polymerase from Ehrlich ascites tumor cells.
[9th symposium on bacterial toxins. 1. On the mechanism of action of toxins. B. Cellular level. 4. On the mechanism of toxic action of diphtheria toxin on Ehrlich ascites tumor cells.]
[Antitumor effect of diphtheria toxin on Ehrlich ascites tumor in mice]
[THE EFFECT OF BACTERIAL DESOXYRIBONUCLEASE ON EHRLICH ASCITES TUMOR CELLS IN IN VITRO EXPERIMENTS.]
Carcinoma, Embryonal
BAG-1, a novel Bcl-2-interacting protein, activates expression of human JC virus.
Binding of proteins from embryonic and differentiated cells to a bidirectional promoter contained within a CpG island.
Expression of the alpha-fetoprotein gene in pluripotent and committed cells.
Carcinoma, Hepatocellular
A correlation between nucleosome spacer region susceptibility to DNase I and histone acetylation.
A DNA polymerase activity associated with the skeletal framework of the plasma membranes of a rat hepatoma.
A new form of high molecular weight DNA polymerase in the nuclei of rat ascites hepatoma cells.
A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1.
A Polydeoxythymidylic acid-specific deoxyribonuclease from rat ascites hepatoma cells.
Activities of some enzymes of pyrimidine and DNA synthesis in a rat transplantable hepatoma and human primary hepatomas, in cell lines derived from these tissues, and in human fetal liver.
Albumin and alpha-fetoprotein gene transcription in rat hepatoma cell lines is correlated with specific DNA hypomethylation and altered chromatin structure in the 5' region.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
An 18K protein from ascites hepatoma cell depolymerizes actin filaments rapidly.
C/EBPalpha is a regulator of the UDP glucuronosyltransferase UGT2B1 gene.
Characteristics of DNA repair induced by DNA polymerase ? in hepatoma cells after ?-ray irradiation.
Characterization of functional Sp1 transcription factor binding sites in the hepatitis B virus nucleocapsid promoter.
Characterization of novel hepadnaviral RNA species accumulated in hepatoma cells treated with viral DNA polymerase inhibitors.
Chromatin solubilization in rapidly growing hepatomas.
Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP.
Conversion of DNA polymerase extracted from rat ascites hepatoma cells.
Decorating protein nanospheres with lactoferrin enhances oral COX-2 inhibitor/herbal therapy of hepatocellular carcinoma.
Diagnostic Value of Serum DNASE1L3 in Hepatitis B Virus-Related Hepatocellular Carcinoma.
Differential DNase I sensitivity of the albumin and alpha-fetoprotein genes in chromatin from rat tissues and cell lines.
Diversity of nuclear protein fractions of hamster liver and hepatoma produced by DNaseI.
DNA polymerase activities associated with smooth membranes and ribosomes from rat liver and hepatoma cytoplasm.
DNA polymerase and thymidine kinase activities in MC-29 virus-induced transplantable hepatoma and the effect of cytostatic treatment of these activities.
DNA polymerases of ascites hepatoma cells. I. Purification and properties of a DNA polymerase from soluble fraction.
DNA synthesis in membrane-denuded nuclei and nuclear fractions from host liver and Morris hepatomas.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
DNASE1L3 as an indicator of favorable survival in hepatocellular carcinoma patients following resection.
DNase1L3 suppresses hepatocellular carcinoma growth via inhibiting complement autocrine effect.
Dual-Targeted Lactoferrin Shell-Oily Core Nanocapsules for Synergistic Targeted/Herbal Therapy of Hepatocellular Carcinoma.
Effect of bleomycin on [3H]Thymidine 5'-Triphosphate incorporation into host liver and hepatoma nuclei.
Effect of Smilax china L.-containing serum on the expression of POLD1 mRNA in human hepatocarcinoma SMMC-7721 cells.
Effects of deoxyribonuclease I and micrococcal nuclease on the release of dexamethasone-receptor complex from nuclei of sensitive and insensitive hepatoma cell lines.
Effects of suramin on in vitro HBsAg production by PLC/PRF/5 cells and hepatitis B virus DNA polymerase activity.
Enhanced antitumor efficacy by combination treatment with a human umbilical vein endothelial cell vaccine and a tumor cell lysate-based vaccine.
Enhanced interleukin-2 diphtheria toxin conjugate-induced growth suppression in retinoic acid-treated hypoxic hepatocellular carcinoma cells.
Evidence for involvement of a ribosomal leaky scanning mechanism in the translation of the hepatitis B virus pol gene from the viral pregenome RNA.
Free and integrated forms of hepatitis B virus DNA in human hepatocellular carcinoma cells (PLC/342) propagated in nude mice.
Genetic variation among hepatitis B and related viruses.
Hepatic transcriptional up-regulator of the rat microsomal epoxide hydrolase gene.
Hepatitis B Virus DNA Polymerase Displays an Anti-Apoptotic Effect by Interacting with Elongation Factor-1 Alpha-2 in Hepatoma Cells.
Hepatitis C virus quasispecies in cancerous and noncancerous hepatic lesions: the core protein-encoding region.
Hepatocellular carcinoma targeting effect of PEGylated liposomes modified with lactoferrin.
Hepatocyte-specific interplay of transcription factors at the far-upstream enhancer of the carbamoylphosphate synthetase gene upon glucocorticoid induction.
High molecular weight deoxyribonucleic acid polymerase of LF hepatoma. Purification and properties.
Identification and characterization of a hepatoma cell-specific enhancer in the mouse multidrug resistance mdr1b promoter.
In vitro replication competence of a cloned hepatitis B virus variant with a nonsense mutation in the distal pre-C region.
Increased DNA polymerase activity in a series of rat hepatomas.
Inhibition of DNA polymerase-alpha from rat hepatoma with a series of new synthetic polynucleotides.
Interaction of a hepatoma-specific nuclear factor with transcription-regulatory sequences of the human alpha-fetoprotein and albumin genes.
Involvement of an AFP1-binding site in cell-specific transcription of the pre-S1 region of the human hepatitis B virus surface antigen gene.
Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration.
Lactoferrin-modified PEGylated liposomes loaded with doxorubicin for targeting delivery to hepatocellular carcinoma.
Liver-specific enhancer of the glucokinase gene.
Low molecular weight DNA polymerase of rat ascites hepatoma cells.
Major chromatin changes accompany extinction of alpha-fetoprotein gene in hepatoma x fibroblast hybrids.
Metabolism of 5-fluorouracil in sensitive and resistant tumor cells.
Molecular analysis of the distal enhancer of the mouse alpha-fetoprotein gene.
Mutations in hepatitis B virus polymerase are associated with the postoperative survival of hepatocellular carcinoma patients.
Novel symmetric amphiphilic dendritic poly(L-lysine)-b-poly(L-lactide)-b-dendritic poly(L-lysine) with high plasmid DNA binding affinity as a biodegradable gene carrier.
Periodicity and fragment size of DNA from mouse TLT hepatoma chromatin and chromatin fractions using endogenous and exogenous nucleases.
Possible site of zinc control of hepatoma cell division in Wistar rats.
Proteins and RNA in mouse L cell core nucleoli and nucleolar matrix.
Rat hepatoma DNA polymerase: partial analysis of the in vitro DNA product.
Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNA.
Selective inhibition of hepatoma cells using diphtheria toxin A under the control of the promoter/enhancer region of the human alpha-fetoprotein gene.
Separable DNA polymerase activities in host liver and Morris hepatomas.
Separation of DNA polymerase from rat liver and hepatomas.
Sertoli cell-specific expression of the human transferrin gene. Comparison with the liver-specific expression.
Stimulatory effect of a serum factor on DNA synthesis in isolated hepatoma nuclei.
Studies on the molecular species of DNA polymerase extracted from rat ascites hepatoma cells.
Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids.
Suppression of the delayed cutaneous hypersensitivity response in hepatoma patients: test by antigen of streptokinase and streptodornase.
Systematical analyses of variants in DNase I hypersensitive sites to identify hepatocellular carcinoma susceptibility loci in a Chinese population.
Targeting solid tumors via T cell receptor complementarity-determining region 3delta in an engineered antibody.
The inhibitory effect of 4-hydroxy-nonenal on DNA-polymerases alpha and beta from rat liver and rapidly dividing Yoshida ascites hepatoma.
The phenylpropenamide derivative AT-130 blocks HBV replication at the level of viral RNA packaging.
Therapeutic strategies for a functional cure of chronic hepatitis B virus infection.
Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.
Transcriptional activation of the human papillomavirus-16 P97 promoter by an 88-nucleotide enhancer containing distinct cell-dependent and AP-1-responsive modules.
Tumoricidal Activity of RNase A and DNase I.
Usefulness of ascitic fluid lactoferrin levels in patients with liver cirrhosis.
[3 Types of DNA polymerase in Zajdela ascites hepatoma cells]
[Comparative study on template activity and susceptibility to DNase I digestion of mouse liver and ascites hepatoma cell chromatin]
[Differences in expression and functional organization of the rat tyrosine aminotransferase gene in two lines of Morris hepatoma, 8994 and 7777]
[In vitro targeting effect of lactoferrin modified PEGylated liposomes for hepatoma cells].
[Intranuclear localization of hepatoma chromatin antigens not detected in liver chromatin]
[The activity of nuclear endonucleases and topoisomerases in the liver of rats and in diethylnitrosamine-induced tumors]
Carcinoma, Large Cell
Large cell carcinoma of the lung. Prognostic implications of histopathologic and immunohistochemical subtyping.
Carcinoma, Lewis Lung
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Cd11b(+) myeloid cells support hepatic metastasis through down-regulation of angiopoietin-like 7 in cancer cells.
Quantitative estimation of tumor metastasis by measurement of DNA polymerase activity.
Tumoricidal Activity of RNase A and DNase I.
Carcinoma, Merkel Cell
TdT expression in normal and neoplastic sebaceous cells.
Carcinoma, Mucoepidermoid
Mucoepidermoid carcinoma of the salivary glands: immunohistochemical distribution of intermediate filament proteins, involucrin and secretory proteins.
Mucoepidermoid carcinomas: immunohistochemical studies on keratin, S-100 protein, lactoferrin, lysozyme and amylase.
Carcinoma, Neuroendocrine
TdT expression in normal and neoplastic sebaceous cells.
Carcinoma, Non-Small-Cell Lung
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.
Expression of an X-family DNA polymerase, pol lambda, in the respiratory epithelium of non-small cell lung cancer patients with habitual smoking.
Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer.
Carcinoma, Ovarian Epithelial
Cell kinetics in ovarian cancer. Relationship to clinicopathologic features, responsiveness to chemotherapy, and survival.
Molecular disruption of DNA polymerase ? for platinum sensitisation and synthetic lethality in epithelial ovarian cancers.
Carcinoma, Papillary
Immunohistochemical demonstration of lactoferrin in follicular adenomas and thyroid carcinomas.
Iron-binding proteins in thyroid tumours. An immunocytochemical study.
Lactoferrin demonstration in thyroid follicular and papillary carcinomas.
Lactoferrin in thyroid lesions: immunoreactivity in fine needle aspiration biopsy samples.
Carcinoma, Renal Cell
Cell-specific in vivo DNA-protein interactions at the proximal promoters of the pro alpha 1(I) and the pro alpha2(I) collagen genes.
Cytotoxic effect of diphtheria toxin used alone or in combination with other agents on human renal cell carcinoma cell lines.
Generation of anti-tumour immune response using dendritic cells pulsed with carbonic anhydrase IX-Acinetobacter baumannii outer membrane protein A fusion proteins against renal cell carcinoma.
Immunoexpression of lactoferrin in human sporadic renal cell carcinomas.
Immunostimulatory Activity of Dendritic cells pulsed with carbonic anhydrase IX and Acinetobacter baumannii outer membrane protein A.
Immunotoxins in cancer therapy: Review and update.
Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo.
Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant.
The relationship of lactoferrin to the anemia of renal cell carcinoma.
[Mechanism of p53 gene mutation in the development of urologic cancer]
Carcinoma, Squamous Cell
Angiosarcoma Arising from the Tongue of an 11-Year-Old Girl with Xeroderma Pigmentosum.
Comparison of pyrimidine nucleotide synthetic enzymes involved in 5-fluorouracil metabolism between human adenocarcinomas and squamous cell carcinomas.
Diphtheria toxin prevents catecholamine desensitization of A431 human epidermoid carcinoma cells.
E6/E7 expression of human papillomavirus types in cutaneous squamous cell dysplasia and carcinoma in immunosuppressed organ transplant recipients.
Enhancement of X-ray toxicity in squamous cell carcinoma cell lines by DNA polymerase inhibitors.
In vitro evaluation of the anticancer effect of lactoferrin and tea polyphenol combination on oral carcinoma cells.
Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase ? and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma.
Lactoferrin inhibits growth of malignant tumors of the head and neck.
Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy.
Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo.
Role of p12(CDK2-AP1) in transforming growth factor-beta1-mediated growth suppression.
Tumor antigens in neoplasms of the human parotid gland.
Tumor markers in parotid gland carcinomas: immunohistochemical investigations.
Carcinoma, Verrucous
Verrucous carcinomas of the head and neck, including those with associated squamous cell carcinoma, lack transcriptionally active high-risk human papillomavirus.
Carcinosarcoma
DNA polymerase activities from gel exclusion chromatography of Walker 256 carcinosarcoma extracts.
Effects of oligonucleotides on the Walker 256 carcinosarcoma DNA polymerase reaction.
The influence of lactoferrin on elemental homeostasis and activity of metal-containing enzymes in rats with Walker-256 carcinosarcoma.
Tumor Mutational Burden Guides Therapy in a Treatment Refractory
Cardiomegaly
Lactoferrin ameliorates pathological cardiac hypertrophy related to mitochondrial quality control in aged mice.
Novel Role for Caspase-Activated DNase in the Regulation of Pathological Cardiac Hypertrophy.
Cardiomyopathies
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.
Septic cardiomyopathy: The value of lactoferrin and CD15 as specific markers to corroborate a definitive diagnosis.
Cardiomyopathy, Dilated
Elevated DNase I levels in human idiopathic dilated cardiomyopathy: an indicator of apoptosis?
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Cardiotoxicity
Mitochondrial ultrastructural and molecular changes induced by zidovudine in rat hearts.
The effects of lactoferrin in a rat model of catecholamine cardiotoxicity.
Cardiovascular Diseases
Recombinant lactoferrin (Lf) of Vechur cow, the critical breed of Bos indicus and the Lf gene variants.
Cataplexy
GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy.
Cataract
Dnases in health and disease.
Effect of Oral Lactoferrin on Cataract Surgery Induced Dry Eye: A Randomised Controlled Trial.
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Lactoferrin and serum albumin in the conjunctival fluid of eyes operated for senile cataract.
Mycobacterium leprae infection and serum lactoferrin levels.
Tear lactoferrin concentration during postoperative ocular inflammation in cataract surgery.
The Changes of 8-OHdG, hOGG1, APE1 and Pol ? in Lenses of Patients with Age-Related Cataract.
The concentration of lactoferrin in tears during post-operative ocular inflammation.
Celiac Disease
AGA Technical Review on the Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D).
Immunohistochemical localization of lactoferrin in duodenojejunal mucosa from celiac children.
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
Cellulitis
Characteristics of Escherichia coli isolates from avian cellulitis.
Central Nervous System Diseases
A Review on Lactoferrin and Central Nervous System Diseases.
Integrin alpha 10, CD44, PTEN, cadherin-11 and lactoferrin expressions are potential biomarkers for selecting patients in need of central nervous system prophylaxis in diffuse large B-cell lymphoma.
Central Nervous System Infections
Lactoferrin, lysozyme, and beta 2-microglobulin levels in cerebrospinal fluid: differential indices of CNS inflammation.
Central Nervous System Viral Diseases
Lactoferrin, lysozyme, and beta 2-microglobulin levels in cerebrospinal fluid: differential indices of CNS inflammation.
Cerebellar Ataxia
Atm deficiency in the DNA polymerase ? null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.
Cerebral Hemorrhage
Beneficial Role of Neutrophils Through Function of Lactoferrin After Intracerebral Hemorrhage.
Lactoferrin and hematoma detoxification after intracerebral hemorrhage.
Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage.
Optimized lactoferrin as a highly promising treatment for intracerebral hemorrhage: Pre-clinical experience.
Cerebral Palsy
Lactoferrin versus iron hydroxide polymaltose complex for the treatment of iron deficiency anemia in children with cerebral palsy: a randomized controlled trial.
Cerebrovascular Disorders
Eosinophil cationic protein (ECP) in the cerebrospinal fluid.
Chickenpox
Antiviral lead compounds from marine sponges.
Antiviral sensitivities of the acute retinal necrosis syndrome virus.
Brivudin (bromovinyl deoxyuridine).
Comparative inhibition of DNA polymerases from varicella zoster virus (TK+ and TK-) strains by (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate.
Non-HIV antivirals - a review of the recent patent literature.
Susceptibility of Oka varicella vaccine strain to antiviral drugs.
[Contribution of the laboratory in case of resistance to acyclovir of herpes simplex and varicella zoster virus]
Cholangiocarcinoma
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
Cholangitis
[Study of salivary lactoferrin in prophylactic examinations]
Cholangitis, Sclerosing
Anti-lactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease.
Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.
Antineutrophil cytoplasmic antibodies in primary sclerosing cholangitis: defined specificities may be associated with distinct clinical features.
Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in inflammatory disorders.
Distribution of lactoferrin and 60/65 kDa heat shock protein in normal and inflamed human intestine and liver.
Two spatially distant epitopes of human lactoferrin.
Cholecystitis
Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer.
[Study of salivary lactoferrin in prophylactic examinations]
Cholelithiasis
[Study of salivary lactoferrin in prophylactic examinations]
Cholera
A hybrid toxin containing fragment A from diphtheria toxin linked to the B protomer of cholera toxin.
A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in a Bangladeshi population.
An approach for analysis of protein toxins based on thin films of lipid mixtures in an optical biosensor.
Antibody microarrays for native toxin detection.
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus.
Botulinum C2 toxin ADP-ribosylates actin.
Broad up-regulation of innate defense factors during acute cholera.
Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins.
Comparison of the Vibrio cholerae hemagglutinin/protease and the Pseudomonas aeruginosa elastase.
Computer modelling of the NAD binding site of ADP-ribosylating toxins: active-site structure and mechanism of NAD binding.
Detection of arginine-ADP-ribosylated protein using recombinant ADP-ribosylarginine hydrolase.
Development of novel O-polysaccharide based glycoconjugates for immunization against glanders.
Diphtheria toxin-binding glycoproteins on hamster cells: candidates for diphtheria toxin receptors.
Effects of pseudomonas toxin A, diphtheria toxin, and cholera toxin on electrical characteristics of turtle bladder.
Enhancement of cellular protein synthesis sensitivity to diphtheria toxin by interferon.
Enhancement of common mucosal immunity in aged mice following their supplementation with various antioxidants.
Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
Functional comparison of the NAD binding cleft of ADP-ribosylating toxins.
Highly purified mutant E112K of cholera toxin elicits protective lung mucosal immunity to diphtheria toxin.
Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.
Immunomodulatory effect of bovine lactoferrin pepsin hydrolysate on murine splenocytes and Peyer's patch cells.
Immunoprecipitation and partial characterization of diphtheria toxin-binding glycoproteins from surface of guinea pig cells.
Inhibition by lactoferrin and kappa-casein glycomacropeptide of binding of Cholera toxin to its receptor.
Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states.
mADP-RTs: versatile virulence factors from bacterial pathogens of plants and mammals.
Mono(ADP-ribosyl)ation of 2'-deoxyguanosine residue in DNA by an apoptosis-inducing protein, pierisin-1, from cabbage butterfly.
New evidence for an inflammatory component in diarrhea caused by selected new, live attenuated cholera vaccines and by El Tor and Q139 Vibrio cholerae.
Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells.
Recent advances in microbial toxin-related strategies to combat cancer.
Recombinant human lactoferrin treatment for global health issues: iron deficiency and acute diarrhea.
Sequence and structural links between distant ADP-ribosyltransferase families.
The effect of lincomycin on exoprotein production by Vibrio cholerae.
Transcutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine.
Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin.
Cholestasis
The effect of ursodeoxycholic acid on oxidative stress level and DNase activity in rat liver after bile duct ligation.
Cholesteatoma
Induction of cytokine production in cholesteatoma keratinocytes by extracellular high-mobility group box chromosomal protein 1 combined with DNA released by apoptotic cholesteatoma keratinocytes.
Chondroblastoma
Immunolocalization of lactoferrin in cartilage-forming neoplasms.
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Chondrocalcinosis
Lactoferrin and lysozyme levels in synovial fluid: differential indices of articular inflammation and degradation.
Chondroma
Immunolocalization of lactoferrin in cartilage-forming neoplasms.
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Chondrosarcoma
Immunolocalization of lactoferrin in cartilage-forming neoplasms.
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Chorioamnionitis
Lysozyme in cervical mucus of patients with chorioamnionitis.
[Lactoferrin in cervical mucus of patients with chorioamnionitis]
Choriocarcinoma
Activator protein-2 regulates human placental lactogen gene expression.
The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription.
The methyltrienolone binding protein of JEG-3 cells and human placenta is localized within the nucleus and is tightly associated with chromatin.
Choroidal Neovascularization
Lactoferrin Has a Therapeutic Effect via HIF Inhibition in a Murine Model of Choroidal Neovascularization.
Lactoferrin Reduces Chorioretinal Damage in the Murine Laser Model of Choroidal Neovascularization.
Chronic Periodontitis
Association between lactoferrin gene polymorphisms and aggressive periodontitis among Taiwanese patients.
Effects of orally administered lactoferrin and lactoperoxidase-containing tablets on clinical and bacteriological profiles in chronic periodontitis patients.
Elevated levels of salivary lactoferrin, a marker for chronic periodontitis?
Estimation of lactoferrin levels in gingival crevicular fluid before and after periodontal therapy in patients with chronic periodontitis.
Gingival crevicular fluid lactoferrin levels in adult periodontitis patients.
Lactoferrin and other markers from gingival crevicular fluid and saliva before and after periodontal treatment.
Lactoferrin levels in gingival crevicular fluid and saliva of HIV-infected patients with chronic periodontitis.
Lysozyme and lactoferrin quantitation in the crevicular fluid.
Churg-Strauss Syndrome
[Antineutrophil cytoplasmic antibodies--ANCA]
Ciliary Motility Disorders
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.
Long-term use of nebulized human recombinant DNase1 in two siblings with primary ciliary dyskinesia.
Classical Swine Fever
Epitope mapping and affinity purification of monospecific antibodies by Escherichia coli cell surface display of gene-derived random peptide libraries.
Clostridium Infections
Calprotectin and lactoferrin faecal levels in patients with Clostridium difficile infection (CDI): a prospective cohort study.
Clostridium difficile ribotype 027 is most prevalent among inpatients admitted from long-term care facilities.
Faecal lactoferrin and calprotectin in patients with Clostridium difficile infection: a case-control study.
In vitro activity of the novel antibacterial agent ibezapolstat (ACX-362E) against Clostridioides difficile.
Laboratory diagnosis of clostridium difficile infection. An evaluation of tests for faecal toxin, glutamate dehydrogenase, lactoferrin and toxigenic culture in the diagnostic laboratory.
Potential of lactoferrin to prevent antibiotic-induced Clostridium difficile infection.
Quantitative Fecal Lactoferrin as a Biomarker for Severe Clostridium difficile Infection in Hospitalized Patients.
Ribotype 027 Clostridium difficile infections with measurable stool toxin have increased lactoferrin and are associated with a higher mortality.
Cockayne Syndrome
Characteristics of UV-induced repair patches relative to the nuclear skeleton in human fibroblasts.
Transcription factor TFIIH and DNA endonuclease Rad2 constitute yeast nucleotide excision repair factor 3: implications for nucleotide excision repair and Cockayne syndrome.
Coinfection
Assessment of antibodies against surface and outer membrane proteins of Anaplasma phagocytophilum in Lyme borreliosis and tick-borne encephalitis paediatric patients.
Coinfection of hepatitis C virus in patients with chronic hepatitis B infection.
Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses.
Human cytomegalovirus infection among patients living with AIDS in a tertiary level hospital in India.
Overexpression and purification of the vaccinia virus DNA polymerase.
Plasmodium vivax malaria presenting as acute respiratory distress syndrome: a case report.
Prophylaxis with lactoferrin, a novel antimicrobial agent, in a neonatal rat model of coinfection.
The association between tuberculosis and diphtheria.
[Lactoferrin assay in urethritis and urethral prostatitis]
Colitis
A non-invasive quantitative assay to measure murine intestinal inflammation using the neutrophil marker lactoferrin.
Alteration of DSS-mediated immune cell redistribution in murine colitis by oral colostral immunoglobulin.
Anti-inflammatory activities of human lactoferrin in acute dextran sulphate-induced colitis in mice.
Approach to the patient with infectious colitis.
Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis?
Bovine lactoferrin induces interleukin-11 production in a hepatitis mouse model and human intestinal myofibroblasts.
Can lactoferrin prevent neonatal sepsis and necrotizing enterocolitis?
Comparative activities of milk components in reversing chronic colitis.
Determination of the effects of lactoferrin in a preclinical mouse model of experimental colitis.
Diagnostic advances in inflammatory bowel disease (imaging and laboratory).
Extracellular DNA as a Prognostic and Therapeutic Target in Mouse Colitis under DNase I Treatment.
Fecal lactoferrin, interleukin-1beta, and interleukin-8 are elevated in patients with severe Clostridium difficile colitis.
Immune Checkpoint Inhibitor-Mediated Diarrhea and Colitis: A Clinical Review.
Incidence of colicinogenic strains among human Escherichia coli.
Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis.
Oral administration of lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
Porcine lactoferrin-derived peptide LFP-20 modulates immune homoeostasis to defend lipopolysaccharide-triggered intestinal inflammation in mice.
Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins modulates Treg and ameliorates inflammatory colitis.
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
Colitis, Collagenous
Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Disease and Collagenous Colitis: No Association with Lactoferrin, ?-Glucuronidase, Myeloperoxidase, or Proteinase 3.
Metabolic and inflammatory faecal markers in collagenous colitis.
Colitis, Microscopic
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
Colitis, Ulcerative
Accuracies of fecal calprotectin, lactoferrin, M2-pyruvate kinase, neopterin and zonulin to predict the response to infliximab in ulcerative colitis.
Advantages of fecal lactoferrin measurement during granulocyte and monocyte adsorptive apheresis therapy in ulcerative colitis.
Anti-lactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease.
Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.
Antigen specificity of circulating anti-neutrophil cytoplasmic antibodies in inflammatory bowel disease.
Antineutrophil cytoplasmic antibodies in primary sclerosing cholangitis: defined specificities may be associated with distinct clinical features.
Antineutrophil cytoplasmic antibodies: a still-growing class of autoantibodies in inflammatory disorders.
Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis?
Biochemical Biomarkers of Mucosal Healing for Inflammatory Bowel Disease in Adults.
Calcium pectinate and hyaluronic acid modified lactoferrin nanoparticles loaded rhein with dual-targeting for ulcerative colitis treatment.
Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease.
Clinical utility of fecal biomarkers for the diagnosis and management of inflammatory bowel disease.
Comparison of 4 neutrophil-derived proteins in feces as indicators of disease activity in ulcerative colitis.
Consecutive Monitoring of Fecal Calprotectin and Lactoferrin for the Early Diagnosis and Prediction of Pouchitis after Restorative Proctocolectomy for Ulcerative Colitis.
Determination of faecal inflammatory marker concentration as a noninvasive method of evaluation of pathological activity in children with inflammatory bowel diseases.
Differential excretion of leucocyte granule components in inflammatory bowel disease: implications for pathogenesis.
DNA-bound lactoferrin is the major target for antineutrophil perinuclear cytoplasmic antibodies in ulcerative colitis.
Faecal calprotectin, lactoferrin, M2-pyruvate kinase and S100A12 in severe ulcerative colitis: a prospective multicentre comparison of predicting outcomes and monitoring response.
Faecal lactoferrin is a useful biomarker for mucosal healing in patients with ulcerative colitis during granulocyte and monocyte adsorptive apheresis therapy.
Fecal calprotectin and lactoferrin as predictors of relapse in patients with quiescent ulcerative colitis during maintenance therapy.
Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse.
Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease.
Fecal lactoferrin is a sensitive and specific marker of disease activity in children and young adults with inflammatory bowel disease.
Fecal lactoferrin predicts primary non-response to biologic agents in inflammatory bowel disease.
Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease.
Fecal Lactoferrin, Calprotectin, PMN-Elastase, CRP and White Blood Cell Count as an Indicator for Mucosal Healing and Clinical Course of Disease in Patients with Mild to Moderate Ulcerative Colitis: Post HOC Analysis of a Prospective Clinical Trial.
Fecal lactoferrin, myeloperoxidase and serum C-reactive are effective biomarkers in the assessment of disease activity and severity in patients with idiopathic ulcerative colitis.
Histological Outcomes and Predictive Value of Faecal Markers in Moderately to Severely Active Ulcerative Colitis Patients Receiving Infliximab.
Immune abnormalities and endotoxemia in patients with ulcerative colitis and in their first degree relatives: attempts at neutralizing endotoxin-mediated effects.
Immunochemical detection of human lactoferrin in feces as a new marker for inflammatory gastrointestinal disorders and colon cancer.
Mucosal healing in inflammatory bowel disease-a true paradigm of success?
Neutrophil cytoplasmic antibodies (p-ANCA) in ulcerative colitis.
Neutrophils in Ulcerative Colitis: A review of selected biomarkers and their potential therapeutic implications.
Novel autoantigens of perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) in ulcerative colitis: non-histone chromosomal proteins, HMG1 and HMG2.
p-ANCA target antigens in ulcerative colitis.
Relationship between fecal lactoferrin and inflammatory bowel disease.
Serial Fecal Calprotectin and Lactoferrin Measurements for Early Diagnosis of Pouchitis After Proctocolectomy for Ulcerative Colitis: Is Pouchoscopy No Longer Needed?
Simultaneous assays for Clostridium difficile and faecal lactoferrin in ulcerative colitis.
The use of selected neutrophil protein plasma concentrations in the diagnosis of Crohn's disease and ulcerative colitis - a preliminary report.
Timely Monitoring of Inflammation by Fecal Lactoferrin Rapidly Predicts Therapeutic Response in Inflammatory Bowel Disease.
Two spatially distant epitopes of human lactoferrin.
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
[A study to determine fecal lactoferrin in patients with ulcerative colitis]
[Indicators of inflammatory process in stool in diagnostics and monitoring of inflammatory bowel diseases].
[Measurement of fecal proteins in inflammatory bowel disease--usefulness as an activity index]
[Significance of fecal lactoferrin in evaluation of disease activity in ulcerative colitis]
Colitis-Associated Neoplasms
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Collagen Diseases
Effect of lactoferrin on the phagocytic activity of polymorphonuclear leucocytes isolated from blood of patients with autoimmune diseases and Staphylococcus aureus allergy.
Colonic Diseases
Correlation of faecal calprotectin and lactoferrin with an endoscopic score for Crohn's disease and histological findings.
Colonic Neoplasms
Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells.
Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities.
Deoxyribonuclease 1-like 3 may be a potential prognostic biomarker associated with immune infiltration in colon cancer.
Effect of Heat Treatment on the Antitumor Activity of Lactoferrin in Human Colon Tumor (HT29) Model.
Effect of lactoferrin on the growth of a human colon adenocarcinoma cell line--comparison with transferrin.
Effects of oral bovine lactoferrin on a mouse model of inflammation associated colon cancer.
Evaluation of Antiproliferative Activity, Safety and Biodistribution of Oxaliplatin and 5-Fluorouracil Loaded Lactoferrin Nanoparticles for the Management of Colon Adenocarcinoma: an In Vitro and an In Vivo Study.
Gene expression profile of human colon cancer cells treated with cross-reacting material 197, a diphtheria toxin non-toxic mutant.
Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression.
Immunochemical detection of human lactoferrin in feces as a new marker for inflammatory gastrointestinal disorders and colon cancer.
Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells.
Lactoferricin treatment decreases the rate of cell proliferation of a human colon cancer cell line.
Lactoferrin Exerts Antitumor Effects by Inhibiting Angiogenesis in a HT29 Human Colon Tumor Model.
Monoclonal antibodies to alpha DNA polymerase as a marker of cell proliferative activity.
Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells.
Novel alginate-enclosed chitosan-calcium phosphate-loaded iron-saturated bovine lactoferrin nanocarriers for oral delivery in colon cancer therapy.
Two human colon tumor cell lines with similar nuclease sensitivities have different ethidium bromide binding characteristics.
Colorectal Neoplasms
A Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase ? Cancer-Associated Variant.
A comparison of flow cytometry and immunohistochemistry in human colorectal cancers.
A mutation in POLE predisposing to a multi-tumour phenotype.
AAV-mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response.
Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells.
Association of DNase I phenotype 2 with colorectal carcinoma risk in Japanese populations.
Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways.
Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities.
CHK1 inhibition is synthetically lethal with loss of B-family DNA polymerase function in human lung and colorectal cancer cells.
Clinical applications of DNase I, a genetic marker already used for forensic identification.
Colon cancer-associated DNA polymerase ? variant induces genomic instability and cellular transformation.
Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer.
DNA polymerase ? as a novel target for chemotherapeutic intervention of colorectal cancer.
DNase I enzyme-aided fluorescence signal amplification based on graphene oxide-DNA aptamer interactions for colorectal cancer exosome detection.
Extremely high prevalence of DNASE1*1 allele in African populations.
Frequency of a single nucleotide (A2317G) and 56-bp variable number of tandem repeat polymorphisms within the deoxyribonuclease I gene in five ethnic populations.
Gene expression profile of human colon cancer cells treated with cross-reacting material 197, a diphtheria toxin non-toxic mutant.
High mutational burden in colorectal carcinomas with monoallelic POLE mutations: absence of allelic loss and gene promoter methylation.
Human Pol ?-dependent replication errors and the influence of mismatch repair on their correction.
Inhibition of DMH-DSS-induced colorectal cancer by liposomal bovine lactoferrin in rats.
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Lactoferrin in the Prevention and Treatment of Intestinal Inflammatory Pathologies Associated with Colorectal Cancer Development.
Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase ?.
Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications.
Morphologic, Immunophenotypic and Molecular Features of Hypermutation in Colorectal Carcinomas with Mutations in DNA Polymerase ? (POLE).
MSH6 immunohistochemical heterogeneity in colorectal cancer: comparative sequencing from different tumor areas.
Mutagenic mechanisms of cancer-associated DNA polymerase ? alleles.
Mutations in POLE and survival of colorectal cancer patients--link to disease stage and treatment.
New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis.
NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase ? and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells.
POLD1 and POLE Gene Mutations in Jewish Cohorts of Early-Onset Colorectal Cancer and of Multiple Colorectal Adenomas.
POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer.
Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy.
Suspected Hereditary Cancer Syndromes in Young Patients: Heterogeneous Clinical and Genetic Presentation of Colorectal Cancers.
The combination of lactoferrin and linolenic acid inhibits colorectal tumor growth through activating AMPK/JNK-related apoptosis pathway.
The Emerging Role of Checkpoint Inhibition in Microsatellite Stable Colorectal Cancer.
Two deoxyribonuclease I gene polymorphisms and correlation between genotype and its activity in Japanese population.
Usefulness of ascitic fluid lactoferrin levels in patients with liver cirrhosis.
Coma
Lanthanide Cofactors Accelerate DNA-Catalyzed Synthesis of Branched RNA.
Common Cold
Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations.
Effects of orally administered lactoferrin and lactoperoxidase on symptoms of the common cold.
Lactoferrin for prevention of common viral infections.
Common Variable Immunodeficiency
Salivary defense factors and oral health in patients with common variable immunodeficiency.
Communicable Diseases
Antimicrobial peptides: the ancient arm of the human immune system.
Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.
Diphtheritic angina in the tongue and floor of the mouth: unusual presentation.
Effects of lactoferrin on infectious diseases in Japanese summer: A randomized, double-blinded, placebo-controlled trial.
Experience with pneumococcal polysaccharide conjugate vaccine (conjugated to CRM197 carrier protein) in children and adults.
Influence of oral lactoferrin on Mycobacterium tuberculosis induced immunopathology.
Lactoferrin differently modulates the inflammatory response in epithelial models mimicking human inflammatory and infectious diseases.
Liposomal lactoferrin induced significant increase of the interferon-alpha (IFN-alpha) producibility in healthy volunteers.
Modulation of immunity-related gene expression in small intestines of mice by oral administration of lactoferrin.
Polymorphic sequence of Korean Native goat lactoferrin exhibiting greater antibacterial activity.
Condylomata Acuminata
Optimized Transferosomal Bovine Lactoferrin (BLF) as a Promising Novel Non-Invasive Topical Treatment for Genital Warts Caused by Human Papiluma Virus (HPV).
Congenital Abnormalities
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Mycobacterium leprae infection and serum lactoferrin levels.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Mitochondria in hematopoiesis and hematological diseases.
Conjunctivitis
Lactoferrin in tears in contact lens wearers.
Reducing suspicion of sexual abuse in paediatric chlamydial conjunctivitis using ompA genotyping.
Tear lactoferrin levels in patients with external inflammatory ocular disease.
Tear lysozyme and lactoferrin levels in giant papillary conjunctivitis and vernal conjunctivitis.
Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections.
[Tear lactoferrin content in normal Chinese adults and various ocular diseases]
Conjunctivitis, Allergic
Lactoferrin in tears in contact lens wearers.
Tear lactoferrin levels in patients with external inflammatory ocular disease.
Tear lysozyme and lactoferrin levels in giant papillary conjunctivitis and vernal conjunctivitis.
Conjunctivitis, Viral
Adenovirus types 19 and 37 isolated from viral conjunctivitis in the Kaohsiung area during 1983-1984: molecular epidemiological study by DNA endonuclease cleavage analysis.
Connective Tissue Diseases
Anti-lactoferrin antibodies in patients with connective tissue diseases.
Sialochemical markers of salivary gland involvement with Sjögren's syndrome secondary to rheumatoid arthritis and primary biliary cirrhosis.
Corneal Diseases
Lactoferrin: A Roadmap to the Borderland between Caries and Periodontal Disease.
Corneal Injuries
Lactoferrin protects against UV-B irradiation-induced corneal epithelial damage in rats.
Selenium-binding lactoferrin is taken into corneal epithelial cells by a receptor and prevents corneal damage in dry eye model animals.
Corneal Opacity
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Mycobacterium leprae infection and serum lactoferrin levels.
Corneal Ulcer
[Tear lactoferrin content in normal Chinese adults and various ocular diseases]
Coronary Artery Disease
Correlation Between Arteriosclerosis and Periodontal Condition Assessed by Lactoferrin and ?1-Antitrypsin Levels in Gingival Crevicular Fluid.
Coronary Stenosis
Functional polymorphisms in the LTF gene and risk of coronary artery stenosis.
Multiple inflammatory markers in patients with significant coronary artery disease.
Coronavirus Infections
Age and Location in Severity of COVID-19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?
Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase ?.
Lactoferrin as Protective Natural Barrier of Respiratory and Intestinal Mucosa against Coronavirus Infection and Inflammation.
Cough
Dornase alfa. A review of pharmacoeconomic and quality-of-life aspects of its use in cystic fibrosis.
Effect of a short course of rhDNase on cough and mucociliary clearance in patients with cystic fibrosis.
Enzymatic débridement; particular reference to trypsin and desoxyribonuclease in the control of cough and sputum associated with tuberculosis.
Inhaled mannitol for cystic fibrosis.
Nebulised hypertonic saline for cystic fibrosis.
Pertussis prevalence and its determinants among children with persistent cough in urban Uganda.
The clinical presentations of pulmonary aspergillosis in children with cystic fibrosis - preliminary report.
Thymosin beta4 sequesters actin in cystic fibrosis sputum and decreases sputum cohesivity in vitro.
[From the aspects of complicated diseases]
COVID-19
Age and Location in Severity of COVID-19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?
Antimicrobial peptides and other peptide-like therapeutics as promising candidates to combat SARS-CoV-2.
Consideration of dornase alfa for the treatment of severe COVID-19 acute respiratory distress syndrome.
Could nutritional supplements act as therapeutic adjuvants in COVID-19?
COVID-19 and early human milk lactoferrin.
COVID-19 during Pregnancy and Postpartum.
Dietary and Protective Factors to Halt or Mitigate Progression of Autoimmunity, COVID-19 and Its Associated Metabolic Diseases.
Early human milk lactoferrin during SARS-CoV-2 infection.
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.
Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights.
Immunomodulatory agents as potential therapeutic or preventive strategies for COVID-19.
Lactoferrin as potential preventative and adjunct treatment for COVID-19.
Lactoferrin for the treatment of COVID-19 (Review).
Lactoferrin is an important factor when breastfeeding and COVID-19 are considered.
Lactoferrin: a potential candidate to fight respiratory infections in the pandemic COVID-19 era.
Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.
Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series.
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series.
Preliminary report of in vitro and in vivo effectiveness of dornase alfa on SARS-CoV-2 infection.
Production in Escherichia coli of recombinant COVID-19 spike protein fragments fused to CRM197.
Protective Action of L. salivarius SGL03 and Lactoferrin against COVID-19 Infections in Human Nasopharynx.
Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro.
The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria.
The Prospect of Lactoferrin Use as Adjunctive Agent in Management of SARS-CoV-2 Patients: A Randomized Pilot Study.
The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators.
The Use of Dornase Alfa in the Management of COVID-19-Associated Adult Respiratory Distress Syndrome.
Cowpox
Characterization of wild-type and cidofovir-resistant strains of camelpox, cowpox, monkeypox, and vaccinia viruses.
Effect of interferon on deoxyribonuclease induction in chick fibroblast cultures infected with cowpox virus.
Orthopoxvirus DNA: a comparison of restriction profiles and maps.
Coxsackievirus Infections
[Desoxyribonuclease II activity of the blood in pancreatic necrosis caused by experimental Coxsackie virus infection.]
Crohn Disease
A prospective study of fecal calprotectin and lactoferrin as predictors of small bowel Crohn's disease in patients undergoing capsule endoscopy.
Accuracy of four fecal assays in the diagnosis of colitis.
Anti-lactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease.
Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.
Antigen specificity of circulating anti-neutrophil cytoplasmic antibodies in inflammatory bowel disease.
Antineutrophil cytoplasm autoantibodies against bactericidal/permeability-increasing protein in inflammatory bowel disease.
Assessment of the response of patients with Crohn's disease to biological therapy using new non-invasive markers: lactoferrin and calprotectin.
Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis?
Bovine lactoferrin and Crohn's disease: a case study.
Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease.
Clinical utility of fecal biomarkers for the diagnosis and management of inflammatory bowel disease.
Correlation of faecal calprotectin and lactoferrin with an endoscopic score for Crohn's disease and histological findings.
Crohn's disease activity assessed by fecal calprotectin and lactoferrin: correlation with Crohn's disease activity index and endoscopic findings.
Determination of faecal inflammatory marker concentration as a noninvasive method of evaluation of pathological activity in children with inflammatory bowel diseases.
Differential excretion of leucocyte granule components in inflammatory bowel disease: implications for pathogenesis.
DNase1: No Association with Crohn's Disease in a New Zealand Population.
Faecal calprotectin and lactoferrin are reliable surrogate markers of endoscopic response during Crohn's disease treatment.
Faecal calprotectin and lactoferrin as markers for monitoring disease activity and predicting clinical recurrence in patients with Crohn's disease after ileocolonic resection: A prospective pilot study.
Faecal calprotectin or lactoferrin can identify postoperative recurrence in Crohn's disease.
Faecal lactoferrin, capsule endoscopy and Crohn's disease. Is there a three way relationship? A pilot study.
Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse.
Fecal calprotectin, lactoferrin, and endoscopic disease activity in monitoring anti-TNF-alpha therapy for Crohn's disease.
Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease.
Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease.
Fecal Lactoferrin and Other Putative Fecal Biomarkers in Crohn's Disease: Do They Still Have a Potential Clinical Role?
Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis.
Fecal lactoferrin is a sensitive and specific marker of disease activity in children and young adults with inflammatory bowel disease.
Fecal lactoferrin predicts primary non-response to biologic agents in inflammatory bowel disease.
Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease.
Fecal lactoferrin: a new parameter to monitor infliximab therapy.
Fecal leukocyte proteins in inflammatory bowel disease and irritable bowel syndrome.
Immunochemical detection of human lactoferrin in feces as a new marker for inflammatory gastrointestinal disorders and colon cancer.
Incorporating functional annotation information in prioritizing disease associated SNPs from genome wide association studies.
Lactoferrin in whole gut lavage fluid as a marker for disease activity in inflammatory bowel disease: comparison with other neutrophil-derived proteins.
Lactoferrin prevents invasion and inflammatory response following E. coli strain LF82 infection in experimental model of Crohn's disease.
Letter: faecal calprotectin and lactoferrin - accurate biomarkers in post-operative Crohn's disease - authors' reply. Letter: biologic therapies are effective for prevention of post-operative Crohn's disease recurrence - authors' reply.
Mucosal healing in inflammatory bowel disease-a true paradigm of success?
Questions and answers on the role of fecal lactoferrin as a biological marker in inflammatory bowel disease.
Relationship between fecal lactoferrin and inflammatory bowel disease.
Relationships between disease activity and serum and fecal biomarkers in patients with Crohn's disease.
Subclinical intestinal inflammation in patients with Crohn's disease following bowel resection: a smoldering fire.
The clinical value of faecal calprotectin and lactoferrin measurement in postoperative Crohn's disease.
The diagnostic usefulness of fecal lactoferrin in the assessment of Crohn's disease activity.
The use of selected neutrophil protein plasma concentrations in the diagnosis of Crohn's disease and ulcerative colitis - a preliminary report.
Timely Monitoring of Inflammation by Fecal Lactoferrin Rapidly Predicts Therapeutic Response in Inflammatory Bowel Disease.
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
Utility of fecal lactoferrin in identifying Crohn disease activity in children.
[Anti-TNF therapy in treatment of luminal Crohn's disease].
[Indicators of inflammatory process in stool in diagnostics and monitoring of inflammatory bowel diseases].
[Measurement of fecal proteins in inflammatory bowel disease--usefulness as an activity index]
Cross Infection
Clinical Management of Infectious Diarrhea.
Lactoferrin supplementation to prevent nosocomial infections in preterm infants.
Neonatal sepsis: new preventive strategies.
Prevention of nosocomial infections in critically ill patients with lactoferrin (PREVAIL study): study protocol for a randomized controlled trial.
Prevention of Nosocomial Infections in Critically Ill Patients With Lactoferrin: A Randomized, Double-Blind, Placebo-Controlled Study.
Cryptorchidism
The effect of experimental cryptorchidism on testicular DNA polymerase activities in the mouse.
Cryptosporidiosis
Dendritic cells play a role in host susceptibility to Cryptosporidium parvum infection.
Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis.
Killing of Cryptosporidium sporozoites by Lactoferrin.
Cystadenocarcinoma
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.
Cystic Fibrosis
A case-controlled study with dornase alfa to evaluate impact on disease progression over a 4-year period.
A cost-effectiveness analysis of rhDNase in children with cystic fibrosis.
A crossover, randomized, controlled trial of dornase alfa before versus after physiotherapy in cystic fibrosis.
A first-year dornase alfa treatment impact on clinical parameters of patients with cystic fibrosis: the Brazilian cystic fibrosis multicenter study.
A multinational economic evaluation of rhDNase in the treatment of cystic fibrosis.
A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis.
A pulmonary exacerbation risk score among cystic fibrosis patients not receiving recommended care.
A six-month study of growth and energy expenditure in children with cystic fibrosis taking a pulmonary inhalation medication (rhDNase).
A technical feasibility study of dornase alfa delivery with eflow(R) vibrating membrane nebulizers: Aerosol characteristics and physicochemical stability.
A two-year randomized, placebo-controlled trial of dornase alfa in young patients with cystic fibrosis with mild lung function abnormalities.
A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in a Bangladeshi population.
AARC Clinical Practice Guideline: Effectiveness of Pharmacologic Airway Clearance Therapies in Hospitalized Patients.
Activity of hypothiocyanite and lactoferrin (ALX-009) against respiratory cystic fibrosis pathogens in sputum.
Additive effect of dornase alfa and Nacystelyn on transportability and viscoelasticity of cystic fibrosis sputum.
Adherence to Dornase Alfa Treatment Among Commercially Insured Patients with Cystic Fibrosis.
Advances in the treatment of cystic fibrosis.
Aerosol delivery and safety of recombinant human deoxyribonuclease in young children with cystic fibrosis: a bronchoscopic study. Pulmozyme Pediatric Broncoscopy Study Group.
Aerosol delivery of recombinant human DNase I: in vitro comparison of a vibrating-mesh nebulizer with a jet nebulizer.
Aerosolized Bovine Lactoferrin Counteracts Infection, Inflammation and Iron Dysbalance in A Cystic Fibrosis Mouse Model of Pseudomonas aeruginosa Chronic Lung Infection.
Aerosolized deoxyribonuclease for cystic fibrosis.
Aerosolized dornase alfa (rhDNase) for therapy of cystic fibrosis.
Aerosolized dornase alfa in cystic fibrosis: is there a role in the management of patients with early obstructive lung disease?
Aerosolized dornase alpha (rhDNase) in cystic fibrosis.
Aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis.
Aerosolized recombinant human DNase I for the treatment of cystic fibrosis.
Airway inflammation after treatment with aerosolized deoxyribonuclease in cystic fibrosis.
An evaluation of two aerosol delivery systems for rhDNase.
Antibiotic tolerance induced by lactoferrin in clinical Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and functionalisation with dornase alfa (DNase).
Bolus inhalation of rhDNase with the AERx system in subjects with cystic fibrosis.
Bovine lactoferrin interacts with cable pili of Burkholderia cenocepacia.
Bronchoscopic instillation of DNase to manage refractory lobar atelectasis in a lung cancer patient.
Bronchoscopy in paediatric intensive care.
Cationic polypeptides are required for antibacterial activity of human airway fluid.
Clinical use of dornase alfa is associated with a slower rate of FEV(1) decline in cystic fibrosis.
Cloning and characterization of a novel human DNase.
Combination of hypothiocyanite and lactoferrin (ALX-109) enhances the ability of tobramycin and aztreonam to eliminate Pseudomonas aeruginosa biofilms growing on cystic fibrosis airway epithelial cells.
Compaction assay: a rapid and simple in vitro method to assess the responsiveness of a biopolymer matrix to enzymatic modification.
Comparative biochemical properties of vertebrate deoxyribonuclease I.
Comparison of FEV1 reference equations for evaluating a cystic fibrosis therapeutic intervention.
Comparison of hypertonic saline and alternate-day or daily recombinant human deoxyribonuclease in children with cystic fibrosis: a randomised trial.
Comparison of three jet nebulizer aerosol delivery systems used to administer recombinant human DNase I to patients with cystic fibrosis. The Pulmozyme rhDNase Study Group.
Cost Effectiveness of Inhaled Mannitol (Bronchitol®) in Patients with Cystic Fibrosis.
Cystic fibrosis clinical characteristics associated with dornase alfa treatment regimen change.
Deoxyribonuclease for cystic fibrosis.
Deoxyribonuclease I and its clinical applications.
DNA concentrations in BAL fluid of cystic fibrosis patients with early lung disease: influence of treatment with dornase alpha.
DNase I acutely increases cystic fibrosis sputum elastase activity and its potential to induce lung hemorrhage in mice.
DNase in stable cystic fibrosis infants: a pilot study.
DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis.
DNase trials in cystic fibrosis.
Dornase alfa (Pulmozyme).
Dornase alfa and rate of lung function decline in European patients with cystic fibrosis: A retrospective registry cohort study.
Dornase alfa approved for use by cystic fibrosis patients.
Dornase alfa as postoperative therapy in cystic fibrosis sinonasal disease.
Dornase alfa for cystic fibrosis.
Dornase alfa for cystic fibrosis. Evidence supporting use of this drug has not yet been published.
Dornase alfa for cystic fibrosis. Patients should not be denied a safe, effective treatment.
Dornase alfa in early cystic fibrosis lung disease.
Dornase alfa in the treatment of cystic fibrosis in Europe: a report from the Epidemiologic Registry of Cystic Fibrosis.
Dornase alfa in young patients with cystic fibrosis.
Dornase alfa is well tolerated: data from the epidemiologic registry of cystic fibrosis.
Dornase alfa reduces air trapping in children with mild cystic fibrosis lung disease: a quantitative analysis.
Dornase alfa therapy in cystic fibrosis: who should get it?
Dornase alfa.
Dornase alfa. A review of its pharmacological properties and therapeutic potential in cystic fibrosis.
Dornase alfa. A review of pharmacoeconomic and quality-of-life aspects of its use in cystic fibrosis.
Dornase alfa: a new option in the management of cystic fibrosis.
Dornase alpha and exhaled NO in cystic fibrosis.
Dornase alpha and survival of patients with cystic fibrosis.
Dornase alpha in the management of a mechanically ventilated infant with cystic fibrosis.
Dornase alpha use in patients with cystic fibrosis.
Dose-dependent in vitro effect of recombinant human DNase on rheological and transport properties of cystic fibrosis respiratory mucus.
Dry powders for the inhalation of ciprofloxacin or levofloxacin combined with a mucolytic agent for cystic fibrosis patients.
Early treatment with dornase alfa in cystic fibrosis: what are the issues?
Editorial for effect of dornase alfa on inflammation and lung function: Potential role in the early treatment of cystic fibrosis.
Effect of a short course of rhDNase on cough and mucociliary clearance in patients with cystic fibrosis.
Effect of aerosolized rhDNase (Pulmozyme(R)) on pulmonary colonization in patients with cystic fibrosis.
Effect of dornase alfa on inflammation and lung function: Potential role in the early treatment of cystic fibrosis.
Effect of ivacaftor therapy on exhaled nitric oxide in patients with cystic fibrosis.
Effect of rhDNase on airflow obstruction and mucociliary clearance in cystic fibrosis.
Effect of rhDNase on lung function and quality of life in adult cystic fibrosis patients.
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis. Dornase Alfa Nebulizer Group.
Effect of treatment with dornase alpha on airway inflammation in patients with cystic fibrosis.
Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease. Pulmozyme Study Group.
Effects of administration of aerosolized recombinant human deoxyribonuclease on resting energy expenditure in patients with cystic fibrosis.
Effects of hypertonic saline, alternate day and daily rhDNase on healthcare use, costs and outcomes in children with cystic fibrosis.
Effects of rhDNase on purulent airway secretions in chronic bronchitis.
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.
Efficacy and safety of short-term administration of aerosolised recombinant human DNase I in adults with stable stage cystic fibrosis.
Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis.
Engineering actin-resistant human DNase I for treatment of cystic fibrosis.
Engineering hyperactive variants of human deoxyribonuclease I by altering its functional mechanism.
Estimating effectiveness in an observational study: a case study of dornase alfa in cystic fibrosis. The Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis.
Estimation of Proinflammatory Factors in the Saliva of Adult Patients with Cystic Fibrosis and Dental Caries.
Expression and characterization of a DNase I-Fc fusion enzyme.
Gelsolin activates DNase I in vitro and cystic fibrosis sputum.
Human neutrophil lipocalin, a highly specific marker for acute exacerbation in cystic fibrosis.
Hyperactivity of human DNase I variants. Dependence on the number of positively charged residues and concentration, length, and environment of DNA.
Hypertonic saline and recombinant human DNase: a randomised cross-over pilot study in patients with cystic fibrosis.
Hypertonic saline treatment of cystic fibrosis.
Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans.
Impact of Clinical, Unit-Specific Guidelines on Dornase Alfa Use in Critically Ill Pediatric Patients Without Cystic Fibrosis.
Impact of PEGylation on the mucolytic activity of recombinant human deoxyribonuclease I in cystic fibrosis sputum.
Improved activity of an actin-resistant DNase I variant on the cystic fibrosis airway secretions.
Improved potency of hyperactive and actin-resistant human DNase I variants for treatment of cystic fibrosis and systemic lupus erythematosus.
Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation.
Improvements in lung function outcomes in children with cystic fibrosis are associated with better nutrition, fewer chronic pseudomonas aeruginosa infections, and dornase alfa use.
In vivo effects of recombinant human DNase I on sputum in patients with cystic fibrosis.
Inflammatory markers in cystic fibrosis.
Inhalable Antibiotic Delivery Using a Dry Powder Co-delivering Recombinant Deoxyribonuclease and Ciprofloxacin for Treatment of Cystic Fibrosis.
Inhalable DNase I microparticles engineered with biologically active excipients.
Inhaled mannitol for cystic fibrosis.
Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment.
Investigating the effects of long-term dornase alfa use on lung function using registry data.
Is a longer time interval between recombinant human deoxyribonuclease (dornase alfa) and chest physiotherapy better?: A multi-center, randomized crossover trial.
Lactoferrin decreases inflammatory response by cystic fibrosis bronchial cells invaded with Burkholderia cenocepacia iron-modulated biofilm.
Lobar atelectasis in cystic fibrosis and treatment with recombinant human DNase I.
Loss of microbicidal activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis.
Mannitol dry powder for inhalation: in patients with cystic fibrosis.
Matrix metalloproteases in BAL fluid of patients with cystic fibrosis and their modulation by treatment with dornase alpha.
Medical interventions for chronic rhinosinusitis in cystic fibrosis.
Medium term treatment of stable stage cystic fibrosis with recombinant human DNase I.
MICs of rifampicin and chloramphenicol for mucoid Pseudomonas aeruginosa strains are lower when human lactoferrin is present.
Model of mucociliary clearance in cystic fibrosis lungs.
Mutational analysis of human DNase I at the DNA binding interface: implications for DNA recognition, catalysis, and metal ion dependence.
Nasally inhaled dornase alfa in the postoperative management of chronic sinusitis due to cystic fibrosis.
Nebulised dornase alpha: adherence in adults with cystic fibrosis.
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series.
New treatment strategies in cystic fibrosis: rhDNase.
No positive effect of rhdnase on the pulmonary colonization in children with cystic fibrosis.
Pharmacoeconomic review of recombinant human DNase in the management of cystic fibrosis.
Plasma and serum lactoferrin levels in cystic fibrosis. Relationship with the presence of cystic fibrosis protein.
Plasma lactoferrin levels in pregnancy and cystic fibrosis.
Plasma levels of lactoferrin in children suffering from cystic fibrosis.
Predicting response to rhDNase and hypertonic saline in children with cystic fibrosis.
Preliminary report of in vitro and in vivo effectiveness of dornase alfa on SARS-CoV-2 infection.
Production and characterization of a PEGylated derivative of recombinant human deoxyribonuclease I for cystic fibrosis therapy.
Randomized trial of efficacy and safety of dornase alfa delivered by eRapid nebulizer in cystic fibrosis patients.
Recombinant DNase in cystic fibrosis: a protocol for targeted introduction through n-of-1 trials. Scottish Cystic Fibrosis Group.
Recombinant human deoxyribonuclease for cystic fibrosis.
Recombinant human deoxyribonuclease for hematopoietic stem cell processing.
Recombinant human deoxyribonuclease shortens ventilation time in young, mechanically ventilated children.
Recombinant human deoxyribonuclease therapy improves airway resistance and reduces DNA extracellular traps in a murine acute asthma model.
Recombinant human DNase I in cystic fibrosis patients with severe pulmonary disease: a short-term, double-blind study followed by six months open-label treatment.
Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum.
Recombinant human DNase nebulisation in children with cystic fibrosis: before bedtime or after waking up?
Reverse transcription-polymerase chain reaction (RT-PCR) phenotypic analysis of cell cultures of human tracheal epithelium, tracheobronchial glands, and lung carcinomas.
Review of recombinant human deoxyribonuclease (rhDNase) in the management of patients with cystic fibrosis.
RhDNase I aerosol deposition and related factors in cystic fibrosis.
Rheology of cystic fibrosis sputum after in vitro treatment with hypertonic saline alone and in combination with recombinant human deoxyribonuclease I.
Safety of repeated intermittent courses of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis.
Serum concentrations of a granulocyte-derived calcium-binding protein in cystic fibrosis patients and heterozygotes.
Sinonasal inhalation of dornase alfa administered by vibrating aerosol to cystic fibrosis patients: A double-blind placebo-controlled cross-over trial.
Small airway deposition of dornase alfa during exacerbations in cystic fibrosis; a randomized controlled clinical trial.
Statistical analysis of the long-term effects of recombinant human deoxyribonuclease on pulmonary function in cystic fibrosis patients.
Taming hyperactive hDNase I: Stable inducible expression of a hyperactive salt- and actin-resistant variant of human deoxyribonuclease I in CHO cells.
Targeting of dornase alpha therapy in adult cystic fibrosis.
The effect of dornase alfa on ventilation inhomogeneity in patients with cystic fibrosis.
The effect of human lactoferrin on the MICs of doxycycline and rifampicin for Burkholderia cepacia and Pseudomonas aeruginosa strains.
The effect of recombinant human lactoferrin on growth and the antibiotic susceptibility of the cystic fibrosis pathogen Burkholderia cepacia complex when cultured planktonically or as biofilms.
The expanding armamentarium of drugs to aid sputum clearance: how should they be used to optimize care?
The overuse or underuse of dornase alfa.
The role of dornase alfa in the treatment of cystic fibrosis.
The sensitivity of cystic fibrosis cells to diphtheria toxin.
The structure of human DNase I bound to magnesium and phosphate ions points to a catalytic mechanism common to members of the DNase I-like superfamily.
The use of human deoxyribonuclease (rhDNase) in the management of cystic fibrosis.
Timing of dornase alfa inhalation for cystic fibrosis.
Timing of dornase alpha inhalation does not affect the efficacy of an airway clearance regimen in adults with cystic fibrosis: a randomised crossover trial.
Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.
Treatment of chronic rhinosinusitis with dornase alfa in patients with cystic fibrosis: a systematic review.
Treatment of lobar atelectasis with bronchoscopically administered recombinant human deoxyribonuclease in cystic fibrosis?
Two years experience with recombinant human DNase I in the treatment of pulmonary disease in cystic fibrosis.
Use of rhDNase therapy and costs of respiratory-related care in patients with cystic fibrosis.
Withdrawal of dornase alfa increases ventilation inhomogeneity in children with cystic fibrosis.
[2 significant stages in the management of mucoviscidosis: the French experience with dornase alfa (Pulmozyme) and the impact in international registries]
[Clinical development of rhDNase in the United States]
[Current therapeutic agents: dornase alfa]
[Effect of rhDNase on rheologic properties and transport capacity of mucus in cystic fibrosis]
[Effect of rhDNase on the respiratory function and nutritional status of children and adolescents with mucoviscidosis]
[Pharmacological and clinical profiles of Dornase alfa (Pulmozyme®) in the management of cystic fibrosis patients to improve pulmonary function].
[Respiratory evolution of patient with mucoviscidosis treated with mucolytic agents plus dornase alfa]
[Swiss registry for patients with cystic fibrosis: design, programming, implementation and first examples of use]
[Treatment of airway inflammation in cystic fibrosis]
Cystitis
The association between colicinogenicity and pathogenesis among uropathogenic isolates of Escherichia coli.
Cysts
DNA polymerase activity in encysting Entamoeba invadens.
First Report of Globodera rostochiensis in Mallorca Island, Spain
First Report of Globodera rostochiensis in Mallorca Island, Spain.
Lactoferrin amyloid presenting as a mural nodule in a pancreatic cystic lesion prompting pancreatoduodenectomy: a case report.
Lactoferrin and lactoferricin endocytosis halt Giardia cell growth and prevent infective cyst production.
Lactoferrin in aspirates of odontogenic cyst fluid.
Protein concentrations in fluid from gross cystic disease of the breast.
Quantitation of lactoferrin in odontogenic cyst fluids.
Cytochrome-c Oxidase Deficiency
Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation.
Cytomegalovirus Infections
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.
Biliary calprotectin, lactoferrin and dimeric pyruvate kinase after liver transplantation are associated with biliary damage and graft survival in a case-control study.
Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection.
Cidofovir incorporation into human keratinocytes with episomal HPV 16 results in nonselective cytotoxicity.
Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo.
Deafness
Functional analysis of POLD1 p.ser605del variant: the aging phenotype of MDPL syndrome is associated with an impaired DNA repair capacity.
Decompression Sickness
Cryo-EM Structure of Actin Filaments from Zea mays Pollen.
DNA-bend modulation in a repressor-to-activator switching mechanism.
DNase I footprinting, DNA bending and in vitro transcription analyses of ClcR and CatR interactions with the clcABD promoter: evidence of a conserved transcriptional activation mechanism.
DNase I-induced DNA conformation. 2 A structure of a DNase I-octamer complex.
Importance of tetramer formation by the nitrogen assimilation control protein for strong repression of glutamate dehydrogenase formation in Klebsiella pneumoniae.
Regulation of anaerobic arginine catabolism in Bacillus licheniformis by a protein of the Crp/Fnr family.
Tension-dependent DNA cleavage by restriction endonucleases: two-site enzymes are "switched off" at low force.
Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication.
Dehydration
A multisite, randomized field trial to evaluate the influence of lactoferrin on the morbidity and mortality of dairy calves with diarrhea.
Applicability of using acrylic resins in post-embedding ultrastructural immunolabelling of human neutrophil granule proteins.
Clinical Management of Infectious Diarrhea.
Detection of DNA polymerase ? activity during seed germination and enhancement after salinity stress and dehydration in the plumules of indica rice (Oryza sativa L.
Human neutrophil lipocalin (HNL) is a specific granule constituent of the neutrophil granulocyte. Studies in bronchial and lung parenchymal tissue and peripheral blood cells.
Molecular dynamics simulations of a membrane protein-micelle complex in vacuo.
Dementia
Effect of deoxyribonuclease I treatment for dementia in end-stage Alzheimer's disease: a case report.
Lactoferrin in cerebrospinal fluid and saliva is not a diagnostic biomarker for Alzheimer's disease in a mixed memory clinic population.
Oxidative-stress associated parameters (lactoferrin, superoxide dismutases) in serum of patients with Alzheimer's disease.
Demyelinating Diseases
An ultrastructural study of experimental demyelination and remyelination. V. Central and peripheral nervous system lesions caused by diphtheria toxin.
Central demyelination produced by diphtheria toxin: an electron microscopic study.
Demyelination and remyelination in the rat central nervous system following ethidium bromide injection.
Demyelination following diphtheria toxin in the presence of axonal atrophy.
Demyelination of Sternarchus electrocyte fibers by injection of diphtheria toxin.
Ectopic activity in demyelinated spinal root axons of the rat.
Effect of diphtheritic demyelination on axonal transport in the sciatic nerve and subsequent muscle changes in the chicken.
Electrical properties of isolated demyelinated rat nerve fibres.
Experimental diphtheritic neuropathy in the mouse: a study in cellular resistance.
Peripheral nerve segmental demyelination induced by intraneural diphtheria toxin injection. I. Effect of hydrocortisone as measured by muscle twitch tension.
Peripheral nerve segmental demyelination induced by intraneural diphtheria toxin injection. Sodium Na 24 and carbon 14-labeled inulin kinetics in diphtheria toxin-injected nerve and the effect of hydrocortisone.
Remyelination by cells introduced into a stable demyelinating lesion in the central nervous system.
Specific permeability properties of demyelinated rat nerve fibres.
The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres.
The internodal axon membrane: electrical excitability and continuous conduction in segmental demyelination.
The spatial distribution of excitability and membrane current in normal and demyelinated mammalian nerve fibres.
Ultrastructural features of viral leukoencephalomyelitis of goats.
[Results of muscle biopsies in diphtheritic polyneuropathy. Light- and electron-microscopic examinations of muscle fibers, intramuscular nerves, motor endplates, and intramuscular vessels]
Dengue
Bovine Lactoferrin Inhibits Dengue Virus Infectivity by Interacting with Heparan Sulfate, Low-Density Lipoprotein Receptor, and DC-SIGN.
Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation.
Dental Caries
Antimicrobial Capacity of a Hydroxyapatite-Lysozyme-Lactoferrin-Lactoperoxidase Combination Against Streptococcus mutans for the Treatment of Dentinal Caries.
Antimicrobial factors of saliva in relation to dental caries and salivary levels of mutans streptococci.
Antimicrobial systems of human whole saliva in relation to dental caries, cariogenic bacteria, and gingival inflammation in young adults.
Both lactoferrin and iron influence aggregation and biofilm formation in Streptococcus mutans.
Effects of topical application of free and liposome-encapsulated lactoferrin and lactoperoxidase on oral microbiota and dental caries in rats.
Lack of associations between lactoferrin (LTF) and mannose-binding lectin 2 (MBL2) gene polymorphism and dental caries susceptibility.
Lactoferrin gene polymorphisms in Italian patients with recurrent tonsillitis.
Relationship of Salivary Lactoferrin and Lysozyme Concentrations with Early Childhood Caries.
Structural integrity of host defense factors in dental plaque.
[Relationship of concentration of lactoferrin and lysozyme in saliva and dental caries in primary dentition]
Dental Plaque
Antimicrobial proteins in human unstimulated whole saliva in relation to each other, and to measures of health status, dental plaque accumulation and composition.
Correlation of lactoferrin with neutrophilic inflammation in body fluids.
Oral health status and development of ventilator-associated pneumonia: a descriptive study.
Quantitative assessment of Scardovia wiggsiae from dental plaque samples of children suffering from severe early childhood caries and caries free children.
Structural integrity of host defense factors in dental plaque.
The relationship between 48-h dental plaque accumulation in young human adults and the concentrations of hypothiocyanite, 'free' and 'total' lysozyme, lactoferrin and secretory immunoglobulin A in saliva.
Dental Pulp Diseases
Human polymorphonuclear granule components: relative levels detected by a modified enzyme-linked immunosorbent assay in normal and inflamed dental pulps.
Dentigerous Cyst
Lactoferrin in aspirates of odontogenic cyst fluid.
Quantitation of lactoferrin in odontogenic cyst fluids.
deoxyribonuclease i deficiency
Abnormal distribution of complex carbohydrates in neutrophils of a patient with lactoferrin deficiency.
Abnormal peroxidase-positive granules in "specific granule" deficiency.
Absence of the largest platelet-von Willebrand multimers in a patient with lactoferrin deficiency and a bleeding tendency.
Acquired Loss of Renal Nuclease Activity Is Restricted to DNaseI and Is an Organ-Selective Feature in Murine Lupus Nephritis.
Anomalous neutrophil granule distribution in a patient with lactoferrin deficiency: pertinence to the respiratory burst.
Congenital and acquired lactoferrin deficiencies in neutrophils.
Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin.
Defence of mucous membranes by antibodies, receptor analogues and non-specific host factors.
Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.
Effect of adenosine 5'-triphosphate-dependent deoxyribonuclease deficiency on properties and transformation of Haemophilus influenzae strains.
Enhanced granulocyte function in a case of chronic granulocytic leukemia in a dog.
Glandular secretion of lactoferrin in a patient with neutrophil lactoferrin deficiency.
Lactoferrin and the inflammatory response.
Lactoferrin deficiency as a consequence of a lack of specific granules in neutrophils from a patient with recurrent infections. Detection by immunoperoxidase staining for lactoferrin and cytochemical electron microscopy.
Lactoferrin deficiency associated with altered granulocyte function.
Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice.
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Lactoferrin-deficient neutrophil polymorphonuclear leucocytes in leukaemias: a semiquantitative and ultrastructural cytochemical study.
Monogenic lupus due to DNASE1L3 deficiency in a pediatric patient with urticarial rash, hypocomplementemia, pulmonary hemorrhage, and immune-complex glomerulonephritis.
Nuclease deficiencies alter plasma cell-free DNA methylation profiles.
Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction.
Progression of murine lupus nephritis is linked to acquired renal Dnase1 deficiency and not to up-regulated apoptosis.
Reversibility of acid and alkaline deoxyribonuclease deficiency in malignant tumor cells.
Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiency.
The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets.
[Neutrophil lactoferrin deficiency]
Dermatitis
Synthesis and anti-herpes simplex activity of analogues of phosphonoacetic acid.
Dermatitis, Atopic
A preliminary approach to creating an overview of lactoferrin multi-functionality utilizing a text mining method.
Expression of T-lineage early developmental markers by cells establishing atopic dermatitis skin infiltrates.
Oral supplementation with bovine whey-derived Ig-rich fraction and lactoferrin improves SCORAD and DLQI in atopic dermatitis.
[Significance of the reactivity to tuberculin, streptokinase and streptodornase in atopic dermatitis]
Dermatitis, Contact
Phytochemical and biological studies of bryophytes.
Dermatitis, Seborrheic
A novel cosmetic antifungal/anti-inflammatory topical gel for the treatment of mild to moderate seborrheic dermatitis of the face: a open-label trial utilizing clinical evaluation and erythemadirected digital photography.
Diabetes Mellitus
Change of some oxidative stress parameters after supplementation with whey protein isolate in patients with type 2 diabetes.
Changes in FGF-23, Neutrophil/Platelet Activation Markers, and Angiogenin in Advanced Chronic Kidney Disease and Their Effect on Arterial Stiffness.
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Evidence-based medicine in cystic fibrosis: how should practice change?
Lactoferrin is a novel predictor of fatal ischemic heart disease in diabetes mellitus type 2: long-term follow-up of the HUNT 1 study.
Salivary innate defense system in type 1 diabetes mellitus in children with mixed and permanent dentition.
[Activity of lysosomal enzymes in diabetes mellitus patients along with diffuse enlargement of the thyroid gland]
Diabetes Mellitus, Experimental
Effect of insulin on DNA synthesis and DNA polymerase activity in organ culture of rat mammary carcinoma, and the inflence of insulin pretreatment and of alloxan diabetes.
[Deoxyribonuclease activity in the tissues of X-ray irradiated animals with alloxan diabetes]
Diabetes Mellitus, Type 1
Blockade of glucagon signaling prevents or reverses diabetes onset only if residual ?-cells persist.
High prevalence of autoantibodies against carbonic anhydrase II and lactoferrin in type 1 diabetes: concept of autoimmune exocrinopathy and endocrinopathy of the pancreas.
How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets.
Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ.
Presence of autoantibodies to carbonic anhidrase II and lactoferrin in type 1 diabetes: proposal of the concept of autoimmune exocrinopathy and endocrinopathy of the pancreas.
Prevalence of autoantibodies to carbonic anhydrase II and lactoferrin in patients with type 1 diabetes.
Salivary innate defense system in type 1 diabetes mellitus in children with mixed and permanent dentition.
Variation in consumption of cow milk proteins and lower incidence of Type 1 diabetes in Iceland vs the other 4 Nordic countries.
Diabetes Mellitus, Type 2
Antidiabetic efficacy of lactoferrin in type 2 diabetic pediatrics; controlling impact on PPAR-?, SIRT-1, and TLR4 downstream signaling pathway.
Change of some oxidative stress parameters after supplementation with whey protein isolate in patients with type 2 diabetes.
Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes.
Increased DNase I activity in diabetes might be associated with injury of pancreas.
Salivary protective factors in patients suffering from decompensated type 2 diabetes.
[An association of selected polymorphisms of the lactoferrin gene and genes for lactoferrin receptors in the prevalence of metabolic disorders in obese subjects].
Diabetes, Gestational
Gestational diabetes mellitus is associated with HLA-DQ beta-chain DNA endonuclease fragments.
Human Milk Secretory Immunoglobulin A and Lactoferrin N-Glycans Are Altered in Women with Gestational Diabetes Mellitus.
Diabetic Retinopathy
Iron-binding proteins in the human vitreous: lactoferrin and transferrin in health and in proliferative intraocular disorders.
Tear film function in type 2 diabetic patients with retinopathy.
Tear Lipocalin and Lipocalin-Interacting Membrane Receptor.
Diphtheria
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1,25-Dihydroxyvitamin D Exerts Similar Immunosuppressive Effects as UVR but Is Dispensable for Local UVR-Induced Immunosuppression.
1-N6-Etheno-ADP-ribosylation of elongation factor-2 by diphtheria toxin.
111Indium labeling of cultured human tumor cells.
11?-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice.
13-valent pneumococcal conjugate vaccine: a review of its use in infants, children, and adolescents.
235 PRODUCTION OF PORCINE KNOCK-IN FIBROBLASTS EXPRESSING HUMAN DECAY-ACCELERATING FACTOR on ?-1,3-GALACTOSYLTRANSFERASE (GGTA1) GENE LOCUS.
3D domain swapping: as domains continue to swap.
A bacteriophage T3 promoter can be linked to a lethal gene without detectable toxicity for eukaryotic cells. Interest for inducible transgenes.
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex.
A bispecific immunotoxin (DTAT13) targeting human IL-13 receptor (IL-13R) and urokinase-type plasminogen activator receptor (uPAR) in a mouse xenograft model.
A Bispecific Recombinant Cytotoxin (DTEGF13) Targeting Human Interleukin-13 and Epidermal Growth Factor Receptors in a Mouse Xenograft Model of Prostate Cancer.
A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma.
A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression.
A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages.
A Brassica S-locus gene promoter targets toxic gene expression and cell death to the pistil and pollen of transgenic Nicotiana.
A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity.
A Case of Cutaneous Blastic Plasmacytoid Dendritic Cell Neoplasm Treated With a Bcl-2 Inhibitor.
A case of cutaneous toxigenic Corynebacterium ulcerans likely acquired from a domestic dog.
A catalytic loop within Pseudomonas aeruginosa exotoxin A modulates its transferase activity.
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly.
A Chinese hamster ovary cell mutant with a heat-sensitive, conditional-lethal defect in vacuolar function.
A CNBR peptide located in the middle region of diphtheria toxin fragment B induces conductance change in lipid bilayers. Possible role of an amphipathic helical segment.
A combination of LightOn gene expression system and tumor microenvironment-responsive nanoparticle delivery system for targeted breast cancer therapy.
A comparative structure-function analysis of active-site inhibitors of Vibrio cholerae cholix toxin.
A comparison of the sensitivity of cell cultures to diphtheria toxin by the dye-uptake method.
A comparison of three strategies for biopanning of phage-scFv library against diphtheria toxin.
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration.
A Critical Role for Monocytes/Macrophages During Intestinal Inflammation-associated Lymphangiogenesis.
A cross-reacting material CRM197 conjugate vaccine induces diphtheria toxin neutralizing antibody response in children and adolescents infected or not with HIV.
A cytotoxic epidermal growth factor cross-linked to diphtheria toxin A-fragment.
A database method for automated map interpretation in protein crystallography.
A diphtheria toxin interleukin-3 fusion protein synergizes with tyrosine kinase inhibitors in killing leukemic progenitors from BCR/ABL positive acute leukemia.
A diphtheria toxin negative selection in RNA interference screening.
A diphtheria toxin receptor deficient in epidermal growth factor-like biological activity.
A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells.
A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin a and diphtheria toxin.
A Dual Role for Corneal Dendritic Cells in Herpes Simplex Keratitis: Local Suppression of Corneal Damage and Promotion of Systemic Viral Dissemination.
A fatal case of necrotizing sinusitis due to toxigenic Corynebacterium ulcerans.
A fold-back single-chain diabody format enhances the bioactivity of an anti-monkey CD3 recombinant diphtheria toxin-based immunotoxin.
A functional role for cysteine disulfides in the transmembrane transport of diphtheria toxin.
A FURTHER STUDY OF NITROGEN RETENTION IN THE BLOOD IN EXPERIMENTAL ACUTE NEPHRITIS.
A genetic method to quantitate induced chromosome breaks using a mouse/human monochromosomal hybrid cell line: identification of potential clastogenic agents.
A glomerular and arterial Lesion produced in Rabbits' Kidneys by Diphtheria Toxin.
A GMMA-CPS-Based Vaccine for Non-Typhoidal Salmonella.
A Hierarchical Approach to Predict Conformation-Dependent Histidine Protonation States in Stable and Flexible Proteins.
A hybrid toxin containing fragment A from diphtheria toxin linked to the B protomer of cholera toxin.
A kinetic analysis of the effects of interleukin-2 diphtheria toxin fusion protein upon activated T cells.
A large-scale Agrobacterium-mediated transformation procedure with a strong positive-negative selection for gene targeting in rice (Oryza sativa L.).
A limited role for regulatory T cells in post-ischemic neovascularization.
A local alignment method for protein structure motifs.
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.
A Method for Encapsulation and Transplantation into Diabetic Mice of Human Induced Pluripotent Stem Cells (hiPSC)-Derived Pancreatic Progenitors.
A model of liver carcinogenesis originating from hepatic progenitor cells with accumulation of genetic alterations.
A model system involving anti-concanavalin A for antibody targeting of diphtheria toxin fragment A1.
A modification-specific peptide-based immunization approach using CRM197 carrier protein: Development of a selective vaccine against pyroglutamate A? peptides.
A modular DNA carrier protein based on the structure of diphtheria toxin mediates target cell-specific gene delivery.
A molecular model of artificial glycoprotein with predetermined multiple immunodeterminants for gram-positive and gram-negative encapsulated bacteria.
A monochromosomal hybrid cell assay for evaluating the genotoxicity of environmental chemicals.
A mouse model of microglia-specific ablation in the embryonic central nervous system.
A mucosal vaccine against diphtheria: formulation of cross reacting material (CRM(197)) of diphtheria toxin with chitosan enhances local and systemic antibody and Th2 responses following nasal delivery.
A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells.
A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells.
A murine model of acute lung injury identifies growth factors to promote tissue repair and their biomarkers.
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens.
A mutation in codon 717 of the CHO-K1 elongation factor 2 gene prevents the first step in the biosynthesis of diphthamide.
A new approach to the detection of autoantibodies against insulin receptors that inhibit the internalization of insulin into human cells.
A new culture method designed for kinetic studies on diphtheria toxin production.
A new design immunotoxin for killing high-grade glioma U87 cells: From in vitro to in vivo.
A new method of recording from the giant fiber of Drosophila melanogaster shows that the strength of its auditory inputs remains constant with age.
A new mouse line for cell ablation by diphtheria toxin subunit A controlled by a Cre-dependent FLEx switch.
A new mouse model for renal lesions produced by intravenous injection of diphtheria toxin A-chain expression plasmid.
A new reagent for the induction of T-cell depletion, anti-CD3-CRM9.
A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells.
A non-invasive QPCR method monitoring DNA based therapy of bladder cancer patients.
A nontoxic diphtheria toxin analogue inhibits neonatal bladder smooth muscle cell proliferation.
A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS.
A novel Amh-Treck transgenic mouse line allows toxin-dependent loss of supporting cells in gonads.
A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells.
A novel experimental platform for toxigenic and non-toxigenic Corynebacterium ulcerans infection in mice.
A Novel Fusion Protein Diphtheria Toxin-Stem Cell Factor (DT-SCF)-Purification and Characterization.
A novel glyco-conjugate vaccine against fungal pathogens.
A novel hairless mouse model on an atopic dermatitis-prone genetic background generated by receptor-mediated transgenesis.
A novel in vivo inducible dendritic cell ablation model in mice.
A novel method for the determination of basal gene expression of tissue-specific promoters: an analysis of prostate-specific promoters.
A novel method to purify immunotoxins from free antibodies using modified recombinant toxins.
A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene.
A novel nonviral vector based on vesicular stomatitis virus.
A novel recombinant immuno-tBid with a furin site effectively suppresses the growth of HER2-positive osteosarcoma cells in vitro.
A Novel Transgenic Mouse Line for Tracing MicroRNA-155-5p Activity In Vivo.
A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells.
A PD-L1-Based Cancer Vaccine Elicits Antitumor Immunity in a Mouse Melanoma Model.
A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer.
A Phase II Trial of Denileukin Diftitox in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer.
A phase-1 trial of bexarotene and denileukin diftitox in patients with relapsed or refractory cutaneous T-cell lymphoma.
A Photo-electric Study of Reactions between Diphtheria Toxin and Antitoxin.
A physico-chemical assessment of the thermal stability of pneumococcal conjugate vaccine components.
A PHYSIOLOGICAL STUDY OF EXPERIMENTAL NEPHRITIS DUE TO BACTERIAL POISONS AND CYTOTOXIC SERA.
A point mutation of proline 308 in diphtheria toxin B chain inhibits membrane translocation of toxin conjugates.
A polymer library approach to suicide gene therapy for cancer.
A postweaning reduction in circulating ghrelin temporarily alters growth hormone (GH) responsiveness to GH-releasing hormone in male mice but does not affect somatic growth.
A procedure to introduce protein molecules into living mammalian cells.
A proper amino terminus of diphtheria toxin is important for cytotoxicity.
A proposed mechanism for ADP ribosylation of aminoacyl transferase II by diphtheria toxin.
A quantitative and highly sensitive luciferase-based assay for bacterial toxins that inhibit protein synthesis.
A randomized comparison of three bivalent Streptococcus pneumoniae glycoprotein conjugate vaccines in young children: effect of polysaccharide size and linkage characteristics.
A Rationally Designed TNF-? Epitope-Scaffold Immunogen Induces Sustained Antibody Response and Alleviates Collagen-Induced Arthritis in Mice.
A recombinant diphtheria toxin related human CD4 fusion protein specifically kills HIV infected cells which express gp120 but selects fusion toxin resistant cells which carry HIV.
A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin.
A regulatory network for the efficient control of transgene expression.
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.
A review of the international issues surrounding the availability and demand for diphtheria antitoxin for therapeutic use.
A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen.
A role for Sfrp2 in cardiomyogenesis in vivo.
A routine high-performance size-exclusion chromatography to determine molecular size distribution of Haemophilus influenzae type b conjugate vaccines.
A screening procedure for the intracellular expression of native proteins by Saccharomyces cerevisiae: discrimination of diphtheria toxin-resistant mutants.
A Self-Assembling Peptide Scaffold for the Multivalent Presentation of Antigens.
A silkworm model of pathogenic bacterial infection.
A single mutation in Chinese hamster ovary cells impairs both Golgi and endosomal functions.
A SNP-based phylogenetic analysis of Corynebacterium diphtheriae in Malaysia.
A Stem Cell Surge During Thyroid Regeneration.
A study of pore formation in lipid bilayers by modular nanotransporters containing the diphtheria toxin translocation domain.
A STUDY OF THE ELIMINATION OF PHENOLSULPHONEPHTHALEIN IN VARIOUS EXPERIMENTAL LESIONS OF THE KIDNEY.
A study of the mechanism of circulatory failure in experimental animals injected with fatal doses of diphtheria toxin.
A subpopulation of itch-sensing neurons marked by Ret and somatostatin expression.
A superactive hormonotoxin prepared with truncated diphtheria toxin.
A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons.
A temperature-sensitive Chinese hamster ovary cell mutant pleiotropically defective in protein export.
A thiol-disulfide oxidoreductase of the Gram-positive pathogen Corynebacterium diphtheriae is essential for viability, pilus assembly, toxin production and virulence.
A three-step scheme for gray crescent formation in the rotated axolotl oocyte.
A tissue culture assay for diphtheria toxicity testing.
A toxin-resistant mouse L-cell mutant defective in protein transport along the secretory pathway.
A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes.
A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection.
A TRIAL OF DEVELOPING A SIMPLE TECHNIQUE OF TITRATING DIPHTHERIA TOXIN ON CULTURES OF EMBRYONIC GUINEA PIG CELLS WITH THE "PLAQUE" TECHNIQUE.
A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin.
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells.
A Universal Positive-Negative Selection System for Gene Targeting in Plants Combining an Antibiotic Resistance Gene and Its Antisense RNA.
A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts.
A versatile partner of eukaryotic protein complexes that is involved in multiple biological processes: Kti11/Dph3.
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin.
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment.
Ablation of a specific cell population by the replacement of a uniquely expressed gene with a toxin gene.
Ablation of AgRP neurons impairs adaption to restricted feeding.
Ablation of breast cancer cells using trastuzumab-functionalized multi-walled carbon nanotubes and trastuzumab-diphtheria toxin conjugate.
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.
Ablation of Central Serotonergic Neurons Decreased REM Sleep and Attenuated Arousal Response.
Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus.
Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain.
Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes.
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions.
Ablation of neurons expressing melanin-concentrating hormone (MCH) in adult mice improves glucose tolerance independent of MCH signaling.
Ablation of NTPDase2+ cells inhibits the formation of filiform papillae in tongue tip.
Ablation of Oxytocin Neurons Causes a Deficit in Cold Stress Response.
Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression.
Ablation of Pericyte-Like Cells in Lungs by Oropharyngeal Aspiration of Diphtheria Toxin.
Ablation of renin-expressing juxtaglomerular cells results in a distinct kidney phenotype.
Ablation of retinal horizontal cells from adult mice leads to rod degeneration and remodeling in the outer retina.
Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure.
Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning.
Ablation of Tpbpa-positive trophoblast precursors leads to defects in maternal spiral artery remodeling in the mouse placenta.
Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells.
Abnormal mutation frequencies in human repair-defective hybrid cell lines.
Abortive infection with Sindbis virus of a Chinese hamster ovary cell mutant defective in phosphatidylserine and phosphatidylethanolamine biosynthesis.
Absence of protective immunity against diphtheria in a large proportion of young adults.
ABT-737 overcomes resistance to immunotoxin-mediated apoptosis and enhances the delivery of pseudomonas exotoxin-based proteins to the cell cytosol.
Accessibility changes within diphtheria toxin T domain upon membrane penetration probed by hydrogen exchange and mass spectrometry.
Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen/deuterium exchange measurements.
Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells.
Acid destabilization of the solution conformation of Bcl-xL does not drive its pH-dependent insertion into membranes.
Acid-triggered membrane insertion of Pseudomonas exotoxin A involves an original mechanism based on pH-regulated tryptophan exposure.
Acidification of endocytic compartments and the intracellular pathways of ligands and receptors.
Acidosis Increases MHC Class II-Restricted Presentation of a Protein Endowed with a pH-Dependent Heparan Sulfate-Binding Ability.
Acquired immunity and allergy of cells cultured in vitro.
Acquitting an APC: DCs found "not guilty" after trial by ablation.
Action of diphtheria toxin does not depend on the induction of large, stable pores across biological membranes.
Action of diphtheria toxin in the guinea pig.
Action of diphtheria toxin on cells cultivated in vitro.
Action of diphtheria toxin on Schizosaccharomyces pombe.
Activated macrophages create lineage-specific microenvironments for pancreatic acinar- and ?-cell regeneration in mice.
Activation of a diphtheria toxin A gene by expression of human immunodeficiency virus-1 Tat and Rev proteins in transfected cells.
ACTIVATION OF DIPHTHERIA TOXIN THROUGH ADJUVANTS. (PRELIMINARY REPORT).
Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.
Active antitoxic immunization by a diphtheria toxin synthetic oligopeptide.
ACTIVE IMMUNITY PRODUCED BY SO CALLED BALANCED OR NEUTRAL MIXTURES OF DIPHTHERIA TOXIN AND ANTITOXIN.
Active immunization induces toxicity of diphtheria toxin in diphtheria resistant mice--implications for neuroinflammatory models.
Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin.
Active target cell processes, possibly involving receptor-mediated endocytosis, are critical for expression of cytotoxicity by natural killer cell-derived cytolytic factor.
Active-site mutations of diphtheria toxin. Tryptophan 50 is a major determinant of NAD affinity.
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine.
Active-site mutations of diphtheria toxin: role of tyrosine-65 in NAD binding and ADP-ribosylation.
Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2.
Activity of diphtheria toxin. II. Early events in the intoxication of HeLa cells.
Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors.
Activity-dependent excitability changes in normal and demyelinated rat spinal root axons.
Activity-dependent regulation of prestin expression in mouse outer hair cells.
Acute Ablation of Cortical Pericytes Leads to Rapid Neurovascular Uncoupling.
Acute ablation of Langerhans cells enhances skin immune responses.
Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively.
Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes.
Acute Intestinal Inflammation Depletes/Recruits Histamine-Expressing Myeloid Cells From the Bone Marrow Leading to Exhaustion of MB-HSCs.
Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins.
Acute myeloid leukemia-targeted toxin activates both apoptotic and necroptotic death mechanisms.
Acute peritonitis due to Corynebacterium ulcerans in a patient receiving continuous ambulatory peritoneal dialysis: a case report and literature review.
Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature.
Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin.
Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin.
Adenosine diphosphoribosylation of aminoacyl transferase II by diphtheria toxin.
Adenovirus-Mediated CRM197 Sensitizes Human Glioma Cells to Gemcitabine by the Mitochondrial Pathway.
Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-induced asthma model.
Adhesion properties of toxigenic corynebacteria.
Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.
Adjuvant Allergen Fusion Proteins as Novel Tools for the Treatment of Type I Allergies.
Adjuvant effect of diphtheria toxin after mucosal administration in both wild type and diphtheria toxin receptor engineered mouse strains.
Adoptive immunotherapy in canine chimeras.
ADP-ribosylated elongation factor 2 (ADP-ribosyl-EF-2) is unable to promote translocation within the ribosome.
ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products.
ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products.
ADP-ribosylation of Translation Elongation Factor 2 by Diphtheria Toxin in Yeast Inhibits Translation and Cell Separation.
ADP-ribosyltransferase from beef liver which ADP-ribosylates elongation factor-2.
Adrenocorticotropin-induced unresponsiveness in cultured adrenal tumor cells.
Adsorption studies on clays. III. The adsorption of diphtheria toxin by activated attapulgites, halloysite, and kaolin.
Adult c-Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons.
Advantages and limitations of mouse models to deplete dendritic cells.
Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice.
Adverse effects of denileukin diftitox and their management in patients with cutaneous T-cell lymphoma.
Aerosolized BC-819 inhibits primary but not secondary lung cancer growth.
Affinity chromatography purification of diphtheria toxin.
Affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and Sepharose beads.
Aggregation and fusion of lipid vesicles induced by diphtheria toxin at low pH: possible involvement of the P site and the NAD+ binding site.
Aire Expression Is Inherent to Most Medullary Thymic Epithelial Cells during Their Differentiation Program.
Allergen-specific immunosuppression by ovalbumin fused with diphtheria toxin in mice sensitized with albumins of different origin.
Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice.
Allergin-1 on mast cells suppresses house dust mite-induced airway hyperresponsiveness in mice.
Alpha-cells are dispensable in postnatal morphogenesis and maturation of mouse pancreatic islets.
Alteration in the ionic properties of aminoacyltransferase II from rat liver by NAD+ and diphtheria toxin.
Alteration of gene expression profiles of peripheral mononuclear blood cells by tobacco smoke: implications for periodontal diseases.
Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.
Alterations in the level of muscle phosphocreatine of guinea pigs produced by the injection of diphtheria toxin.
Altered degradation of epidermal growth factor in a diphtheria toxin-resistant clone of KB cells.
Altered growth hormone-releasing hormone mRNA expression in transgenic mice with excess or deficient endogenous growth hormone.
Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells.
Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension.
Altered ratio of dendritic cell subsets in skin-draining lymph nodes promotes Th2-driven contact hypersensitivity.
Alternation to toxoid of diphtheria toxin by potassium thiocyanate.
Amino acid sequence homology between the enzymic domains of diphtheria toxin and Pseudomonas aeruginosa exotoxin A.
Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins.
Amino acid substitution in alpha-helix 7 of Cry1Ac delta-endotoxin of Bacillus thuringiensis leads to enhanced toxicity to Helicoverpa armigera Hubner.
Amino-acid constitution of diphtheria toxin and toxoid.
Amino-acid sequence of fragment A, an enzymically active fragment from diphtheria toxin.
Amiodarone inhibits lung degradation of SP-A and perturbs the distribution of lysosomal enzymes.
An AGAMOUS intron-driven cytotoxin leads to flowerless tobacco and produces no detrimental effects on vegetative growth of either tobacco or poplar.
An alternative method for purifying and detoxifying diphtheria toxin.
An anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin avoids inhibition by pre-existing antibodies in human blood.
An Anti-PSMA Bivalent Immunotoxin Exhibits Specificity and Efficacy for Prostate Cancer Imaging and Therapy.
An antibacterial vaccination strategy based on a glycoconjugate containing the core lipopolysaccharide tetrasaccharide Hep2Kdo2.
An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor.
An antibody-toxin conjugate directed against a human mammary cancer antigen.
An approach for analysis of protein toxins based on thin films of lipid mixtures in an optical biosensor.
An attempt at elucidating the harmful effect of diphtheria toxin on the brain (isotopic studies). II. Spread of 131-I-albumin in cat brain damaged by diphtheria toxin.
An early effect of diphtheria toxin on the metabolism of mammalian cells growing in culture.
AN EFFECT OF SHORT ELECTRIC WAVES ON DIPHTHERIA TOXIN INDEPENDENT OF THE HEAT FACTOR.
An egg apparatus-specific enhancer of Arabidopsis, identified by enhancer detection.
An endogenous dinucleotide bound to diphtheria toxin. Adenylyl-(3',5')-uridine 3'-monophosphate.
An endosomal model for acid triggering of diphtheria toxin translocation.
An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth.
An Entamoeba histolytica ADP-ribosyl transferase from the diphtheria toxin family modifies the bacterial elongation factor Tu.
An enzyme-linked immunosorbent assay (ELISA) for the determination of diphtheria toxin antibodies.
An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy.
An IgA mimicry of IgG that binds Polymeric Immunoglobulin Receptor for mucosa transcytosis.
An immunological study of the diphtheria toxin molecule.
An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus.
An in situ assay for induced diphtheria-toxin-resistant mutants of diploid human fibroblasts.
An In-vitro Investigation of the Reaction between Diphtheria Toxin and Antitoxin.
An inducible model for specific neutrophil depletion by diphtheria toxin in mice.
An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells.
An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
An olfactory circuit increases the fidelity of visual behavior.
An oncologist's approach to therapy for cutaneous T-cell lymphoma.
An ultrastructural study of experimental demyelination and remyelination. V. Central and peripheral nervous system lesions caused by diphtheria toxin.
Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter.
Analysis of cell-specificity and variegation of transgene expression driven by salmon prolactin promoter in stable lines of transgenic rainbow trout.
Analysis of central blood pressure during diphtheria intoxication in rabbits.
Analysis of DC Functions Using CD205-DTR Knock-In Mice.
Analysis of diphtheria toxin repressor-operator interactions and characterization of a mutant repressor with decreased binding activity for divalent metals.
Analysis of genes that encode DtxR-like transcriptional regulators in pathogenic and saprophytic corynebacterial species.
Analysis of heterogeneity of Corynebacterium diphtheriae toxin gene, tox, and its regulatory element, dtxR, by direct sequencing.
Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery.
Analysis of lens cell fate and eye morphogenesis in transgenic mice ablated for cells of the lens lineage.
Analysis of membrane and surface protein sequences with the hydrophobic moment plot.
Analysis of structure and function of putative surface-exposed proteins encoded in the Streptococcus pneumoniae genome: a bioinformatics-based approach to vaccine and drug design.
Analysis of the cellular immune response induced by Bacillus thuringiensis Cry1A toxins in mice: Effect of the hydrophobic motif from diphtheria toxin.
Analysis of the Corynebacterium diphtheriae DtxR regulon: identification of a putative siderophore synthesis and transport system that is similar to the Yersinia high-pathogenicity island-encoded yersiniabactin synthesis and uptake system.
Analysis of toxigenic Corynebacterium ulcerans strains revealing potential for false-negative real-time PCR results.
Analysis of truncated variants of the iron dependent transcriptional regulators from Corynebacterium diphtheriae and Mycobacterium tuberculosis.
Analyzing topography of membrane-inserted diphtheria toxin T domain using BODIPY-streptavidin: at low pH, helices 8 and 9 form a transmembrane hairpin but helices 5-7 form stable nonclassical inserted segments on the cis side of the bilayer.
Anchoring antibodies to membranes using a diphtheria toxin T domain-ZZ fusion protein as a pH sensitive membrane anchor.
Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice.
Anergy in infants' skin to diphtheria toxin.
Anergy in memory CD4+ T cells is induced by B cells.
Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease.
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin.
Anion-coordinating residues at binding site 1 are essential for the biological activity of the diphtheria toxin repressor.
Anthrax Protective Antigen Retargeted with Single-Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells.
Anti-cancer binary system activated by bacteriophage HK022 integrase.
Anti-CD3 recombinant diphtheria immunotoxin therapy of cutaneous T cell lymphoma.
Anti-glioblastoma effect of a recombinant bispecific cytotoxin cotargeting human IL-13 and EGF receptors in a mouse xenograft model.
Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.
Anti-human HB-EGF Monoclonal Antibodies Inhibiting Ectodomain Shedding of HB-EGF and Diphtheria Toxin Binding.
Anti-idiotypic antibodies that protect cells against the action of diphtheria toxin.
Anti-nicotine vaccines: Comparison of adjuvanted CRM197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates.
Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells.
Antibodies capable of releasing diphtheria toxin in response to the low pH found in endosomes.
Antibody Internalization after Cell Surface Antigen Binding is Critical for Immunotoxin Development.
Antibody microarrays for native toxin detection.
Antibody response to diphtheria, tetanus, and poliomyelitis vaccines in relation to the number of CD4+ T lymphocytes in adults infected with human immunodeficiency virus.
Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.
Antibody Responses After Primary Immunization in Infants Born to Women Receiving a Pertussis-containing Vaccine During Pregnancy: Single Arm Observational Study With a Historical Comparator.
Antibody responses elicited by a polyvalent vaccine containing synthetic diphtheric, streptococcal and hepatitis peptides coupled to the same carrier.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Antibody responses to Bordetella pertussis and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy- a prospective, observational cohort study from the UK.
Antibody responses to Haemophilus influenzae type b and diphtheria toxin induced by conjugates of oligosaccharides of the type b capsule with the nontoxic protein CRM197.
Antibody to lactate dehydrogenase. V. Use as a carrier for introducing diphtheria toxin into mouse tumor cells.
Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells.
Antibody-mediated routing of diphtheria toxin in murine cells results in a highly efficacious immunotoxin.
Anticancer Activity of Bacterial Proteins and Peptides.
Antidiphtheria antibody responses in patients and carriers of Corynebacterium diphtheriae in the Arkhangelsk region of Russia.
Antigen nature and complexity influence human antibody light chain usage and specificity.
Antigenic relationships on the diphtheria toxin molecule: antitoxin versus antitoxoid.
Antineoplastic effect of a diphtheria toxin-based nanoparticle targeting acute myeloid leukemia cells overexpressing CXCR4.
Antitumor activity of DAB389IL-2 fusion toxin in mycosis fungoides.
Antitumor effect of diphtheria toxin A-chain gene-containing cationic liposomes conjugated with monoclonal antibody directed to tumor-associated antigen of bovine leukemia cells.
Antitumor effects of antibody-diphtheria toxin conjugates. II. Immunotherapy with conjugates directed against tumor antigens induced by simian virus 40.
Antitumor effects of antibody-diphtheria toxin conjugates. III. Cyclophosphamide-induced immune unresponsiveness to conjugates.
APOL1 toxin, innate immunity, and kidney injury.
Apolipoprotein-like structure of the N-terminal amino-acid sequence of diphtheria toxin fragment B [proceedings]
Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.
Apoptosis of glutamatergic neurons fails to trigger a neurogenic response in the adult neocortex.
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.
Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells.
Apoptotic neurons induce proliferative responses of progenitor cells in the postnatal neocortex.
Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy.
Application of PCR for detection of toxigenic Corynebacterium diphtheriae strains isolated during the Russian diphtheria epidemic, 1990 through 1994.
Approval of tagraxofusp-erzs for blastic plasmacytoid dendritic cell neoplasm.
Archaebacterial elongation factor is ADP-ribosylated by diphtheria toxin.
Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene.
Artificial hybrid protein containing a toxic protein fragment and a cell membrane receptor-binding moiety in a disulfide conjugate. I. Synthesis of diphtheria toxin fragment A-S-S-human placental lactogen with methyl-5-bromovalerimidate.
Artificial hybrid protein containing a toxic protein fragment and a cell membrane receptor-binding moiety in a disulfide conjugate. II. Biochemical and biologic properties of diphtheria toxin fragment A-S-S-human placental lactogen.
Artificial Salmonella vaccines: O-antigenic oligosaccharide-protein conjugates induce protection against infection with Salmonella typhimurium.
Ascending midbrain dopaminergic axons require descending GAD65 axon fascicles for normal pathfinding.
Ascl3 knockout and cell ablation models reveal complexity of salivary gland maintenance and regeneration.
Asialoglycoprotein receptor mediates the toxic effects of an asialofetuin-diphtheria toxin fragment A conjugate on cultured rat hepatocytes.
Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer.
Assessing the Genetic Diversity of Austrian Corynebacterium diphtheriae Clinical Isolates, 2011 to 2019.
Assignment of ADA, ITPA, AK1, and AK2 to Chinese hamster chromosomes. Genetic and structural evidence for the conservation of mammalian autosomal synteny.
Assignment of hexosaminidase-B to chromosome 5, its segregation after diphtheria toxin selection, and the linkage of hexosaminidase-A, mannose phosphate isomerase, and pyruvate kinase (M2).
Association between diphtheria toxin A- and B-fragment and their fusion proteins.
Association of diphtheria toxin with Vero cells. Demonstration of a receptor.
Association of intravenous administration of human Muse cells with deficit amelioration in a rat model of spinal cord injury.
ATP levels in normal and diphtheria toxin treated cell cultures.
Attenuated diphtheria toxin mediates siRNA delivery.
Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors.
Auditory Responses of Engrailed and Invected-Expressing Johnston's Organ Neurons in Drosophila melanogaster.
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die.
Autoradiographic assay of mutants resistant to diphtheria toxin in mammalian cells in vitro.
Autoradiographic detection of diphtheria toxin resistant mutants in human diploid fibroblasts.
Autoradiographic detection of mutation to exotoxin-A resistance in mouse fibroblasts treated with ethyl methanesulfonate, X-rays and ultraviolet light.
Avian eyelid assay, a new diagnostic method for detecting botulinum neurotoxin serotypes A, B and E.
Avidity and bactericidal activity of antibody elicited by different Haemophilus influenzae type b conjugate vaccines. The Vaccine Study Group.
Avidity as a parameter for diphtheria vaccine efficacy.
Avidity of IgA antibody to Escherichia coli polysaccharide and diphtheria toxin in breast milk from Swedish and Pakistani mothers.
Avidity of specific IgG antibodies elicited by immunisation against Haemophilus influenzae type b.
Back Cover: Eur. J. Immunol. 8'16.
Backbone and side chain (1)H, (13)C and (15)N resonance assignments of the catalytic domain of diphtheria toxin.
Backbone dynamics in an intramolecular prolylpeptide-SH3 complex from the diphtheria toxin repressor, DtxR.
Bacteria and bacterial toxins as therapeutic agents for solid tumors.
Bacteria and their toxins tamed for immunotherapy.
Bacterial flagellin and diphtheria toxin co-stimulate IL-17-producing thymocytes.
Bacterial protein toxins acting on intracellular targets.
Bacterial toxins inhibiting or activating small GTP-binding proteins.
Bacterial toxins.
Bacteriologic Peptone in Relation to the Production of Diphtheria Toxin and Antitoxin.
Bacteriophage-based vectors for site-specific insertion of DNA in the chromosome of Corynebacteria.
BC-819, a plasmid comprising the H19 gene regulatory sequences and diphtheria toxin A, for the potential targeted therapy of cancers.
Behavior of diphtheria toxin T domain containing substitutions that block normal membrane insertion at Pro345 and Leu307: control of deep membrane insertion and coupling between deep insertion of hydrophobic subdomains.
Behavior of intravenously administered I 131 diphtheria toxin in the guinea pig.
Behavior of the deeply inserted helices in diphtheria toxin T domain: helices 5, 8, and 9 interact strongly and promote pore formation, while helices 6/7 limit pore formation.
Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction.
Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network.
Beyond diphtheria toxin: cytotoxic proteins of Corynebacterium ulcerans and Corynebacterium diphtheriae.
BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.
Bilateral adrenal hemorrhage and adrenal insufficiency in a patient with lymphomatous adrenal infiltration following administration of a fusion toxin (DAB486 interleukin-2).
Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells.
Binding of diphtheria toxin to CHO-K1 and Vero cells is dependent on cell density.
Binding of diphtheria toxin to phospholipids in liposomes.
Binding of nicotinamide-adenine dinucleotides to diphtheria toxin.
Binding of nicotinamide–adenine dinucleotides to diphtheria toxin.
Binding of the metalloregulatory protein DtxR to the diphtheria tox operator requires a divalent heavy metal ion and protects the palindromic sequence from DNase I digestion.
Binding of triton X-100 to diphtheria toxin, crossreacting material 45, and their fragments.
Binding properties of diphtheria toxin to cells are altered by mutation in the fragment A domain.
Bioactive IL7-diphtheria fusion toxin secreted by mammalian cells.
Biochemical and biological characteristics of cross-reacting material 197 (CRM(197)), a non-toxic mutant of diphtheria toxin: Use as a conjugation protein in vaccines and other potential clinical applications.
Biochemical and genetic characterization of three hamster cell mutants resistant to diphtheria toxin.
BIOCHEMICAL LESION OF DIPHTHERIA TOXIN IN THE HEART.
Biologic correlates of response and survival in patients with cutaneous T-cell lymphoma treated with denileukin diftitox.
Biological actions of nitroarenes in short-term tests on Salmonella, cultured mammalian cells and cultured human tracheal tissues: possible basis for regulatory control.
Biological activity of heated diphtheria toxin.
Biological and immunological characteristics of lipooligosaccharide-based conjugate vaccines for serotype C Moraxella catarrhalis.
Biological correlates of acute hypersensitivity events with DAB(389)IL-2 (denileukin diftitox, ONTAK) in cutaneous T-cell lymphoma: decreased frequency and severity with steroid premedication.
Biological studies on diphtheria toxin. I. The relation between Dlm and DRM.
Biological studies on diphtheria toxin. II. Skin reaction-inhibitory factor.
Biologically active interleukin 2-ricin A chain fusion proteins may require intracellular proteolytic cleavage to exhibit a cytotoxic effect.
Biology and molecular epidemiology of diphtheria toxin and the tox gene.
Biophysical properties of diphtheria toxin fragment B in correlation to its binding ability to eukaryotic cell membranes [proceedings]
Biosynthesis and processing by phorbol ester of the cells surface-associated precursor form of heparin-binding EGF-like growth factor.
Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase.
Biosynthesis of myelin and neurotoxic factors in the serum of multiple sclerosis patients.
Biosynthesis of organic photosensitizer Zn-porphyrin by diphtheria toxin repressor (DtxR)-mediated global upregulation of engineered heme biosynthesis pathway in Corynebacterium glutamicum.
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus.
BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study.
Blockade of ?-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration.
Blockade of glucagon signaling prevents or reverses diabetes onset only if residual ?-cells persist.
Bmi1 is expressed in vivo in intestinal stem cells.
BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification.
Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling.
Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism.
Bone Marrow-Derived Smooth Muscle-Like Cells Are Infrequent in Advanced Primary Atherosclerotic Plaques but Promote Atherosclerosis.
Bordetella pertussis adenylate cyclase. Penetration into host cells.
Both Corynebacterium diphtheriae DtxR(E175K) and Mycobacterium tuberculosis IdeR(D177K) are dominant positive repressors of IdeR-regulated genes in M. tuberculosis.
Botulinum C2 toxin ADP-ribosylates actin.
Brain Transforming Growth Factor-? Resists Hypertension Via Regulating Microglial Activation.
BReDi mouse: A novel transgenic mouse strain to track and deplete B cells.
Brefeldin A protects ricin-induced cytotoxicity in human cancer KB cell line, but not in its resistant counterpart with altered Golgi structures.
Building a zoo of mice for genetic analyses: a comprehensive protocol for the rapid generation of BAC transgenic mice.
Butyric acid sensitizes Vero cells to ricin-induced apoptosis via accelerated activation of multiple signal transduction pathways.
C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function.
Calcitonin Gene-Related Peptide Biases Langerhans Cells toward Th2-Type Immunity.
Calibration of Distribution Analysis of the Depth of Membrane Penetration Using Simulations and Depth-Dependent Fluorescence Quenching.
Can diphtheria toxin be used for gene therapy of human immunodeficiency virus infection?
Cancer immunity after treatment of Ehrlich tumor with diphtheria toxin.
Cancer-selective induction of cytotoxicity by tissue-specific expression of targeted trans-splicing ribozyme.
Capacity of tumor necrosis factor to bind and penetrate membranes is pH-dependent.
Capture EIA for determination of IgE to diphtheria and tetanus toxins in comparison to RIA.
Cardiotropic effect of intercerebral injections of diphtheria toxin.
Carrier potential properties of Bacillus thuringiensis Cry1A toxins for a diphtheria toxin epitope.
Carrier priming effect of CRM197 is related to an enhanced B and T cell activation in meningococcal serogroup A conjugate vaccination. Immunological comparison between CRM197 and diphtheria toxoid.
Carrier priming to improve pneumococcal disease control and reduce the international program's cost in children.
Carrier priming with CRM 197 or diphtheria toxoid has a different impact on the immunogenicity of the respective glycoconjugates: biophysical and immunochemical interpretation.
Case Report: Suppression of Harem Stallion Behavior and Fertility Following Anti-Gonadotropin-Releasing Hormone Vaccination of a Captive Wild Przewalski's Horse (Equus ferus przewalskii).
Cationic liposome-mediated expression of HIV-regulated luciferase and diphtheria toxin a genes in HeLa cells infected with or expressing HIV.
CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01.
Cd11b(+) myeloid cells support hepatic metastasis through down-regulation of angiopoietin-like 7 in cancer cells.
CD11c+ Cells Are Required for Antigen-Induced Increase of Mast Cells in the Lung.
CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death.
CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis.
CD11c+ M1-like macrophages (M?s) but not CD206+ M2-like M? are involved in folliculogenesis in mice ovary.
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin.
CD123 as a Biomarker in Hematolymphoid Malignancies: Principles of Detection and Targeted Therapies.
CD123 as a Therapeutic Target in the Treatment of Hematological Malignancies.
CD146(+) cells are essential for kidney vasculature development.
CD206+?macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model.
CD25 Expression Is Correlated with Histological Grade and Response to Denileukin Diftitox in Cutaneous T-Cell Lymphoma.
CD4 blockade directly inhibits mouse and human CD4(+) T cell functions independent of Foxp3(+) Tregs.
CD4(+) FoxP3(+) regulatory T cells suppress fatal T helper 2 cell immunity during pulmonary fungal infection.
CD4(+) Foxp3(+) T-cells contribute to myocardial ischemia-reperfusion injury.
CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.
CD9 amino acids critical for upregulation of diphtheria toxin binding.
Cell Ablation Reveals That Expression from the Phaseolin Promoter Is Confined to Embryogenesis and Microsporogenesis.
Cell depleted areas do not repopulate after diphtheria toxin-induced killing of mandibular cartilage chondrocytes.
Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination.
Cell Depletion in Mice That Express Diphtheria Toxin Receptor under the Control of SiglecH Encompasses More Than Plasmacytoid Dendritic Cells.
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene.
Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol.
Cell receptor specific targeted toxins: genetic construction and characterization of an interleukin 2 diphtheria toxin-related fusion protein.
Cell sensitivity to transplacental mutagenesis by N-ethyl-N-nitrosourea is greatest during early gestation in the Syrian hamster.
Cell surface monkey CD9 antigen is a coreceptor that increases diphtheria toxin sensitivity and diphtheria toxin receptor affinity.
Cell surface sulfhydryls are required for the cytotoxicity of diphtheria toxin but not of ricin in Chinese hamster ovary cells.
Cell-free bioluminescent screening of translation inhibitors.
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment.
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH.
Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: potential for cytotoxic gene therapy.
Cell-specific expression of the diphtheria toxin A-chain coding sequence induces cancer cell suicide.
Cell-specific expression of the diphtheria toxin A-chain coding sequence under the control of the upstream region of the human alpha-fetoprotein gene.
Cell-specific modulation of drug resistance in acute myeloid leukemic blasts by diphtheria fusion toxin, DT388-GMCSF.
Cellobiose-coated poly(lactide-co-glycolide) particles loaded with diphtheria toxoid for per os immunization.
Cellular ADP-ribosylation of elongation factor 2.
Cellular ADP-ribosyltransferase with the same mechanism of action as diphtheria toxin and Pseudomonas toxin A.
Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions.
Cellular cytoplasmic delivery of a polypeptide toxin by reconstituted influenza virus envelopes (virosomes).
Cellular Entry of the Diphtheria Toxin Does Not Require the Formation of the Open-Channel State by Its Translocation Domain.
Cellular identification of water gustatory receptor neurons and their central projection pattern in Drosophila.
Cellular mono(ADP-ribosyl) transferase inhibits protein synthesis.
Cellular processing of the interleukin-2 fusion toxin DAB486-IL-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194.
Cellular recovery from exposure to sub-optimal concentrations of AB toxins that inhibit protein synthesis.
Cellular regulation of diphtheria toxin cell surface receptors.
Cellular Source of Cysteinyl Leukotrienes following Chlorine Exposure.
Central demyelination produced by diphtheria toxin: an electron microscopic study.
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis.
Cerulenin inhibits the cytotoxicity of ricin, modeccin, Pseudomonas toxin, and diphtheria toxin in brefeldin A-resistant cell lines.
CGRP?-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch.
CHANGES IN THE ELECTROCARDIOGRAMS ACCOMPANYING EXPERIMENTAL CHANGES IN RABBITS' HEARTS.
Changing the receptor specificity of anthrax toxin.
Channel formation by antiapoptotic protein Bcl-2.
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.
Chaperoning of Insertion of Membrane Proteins into Lipid Bilayers by Hemifluorinated Surfactants: Application to Diphtheria Toxin.
Characterisation of Ppy-lineage cells clarifies the functional heterogeneity of pancreatic beta cells in mice.
Characteristics of guinea-pig immune sera elicited by a synthetic diphtheria toxin oligopeptide.
Characteristics of human antibody to diphtheria toxin.
Characteristics of the reaction between diphtheria toxin, pyridine coenzymes and the GTP-splitting transfer factor FI.
Characterization and affinity labeling of the cationic phosphate-binding (nucleotide-binding) peptide located in the receptor-binding region of the B-fragment of diphtheria toxin.
Characterization and receptor specific toxicity of two diphtheria toxin-related interleukin-3 fusion proteins DAB389-mIL-3 and DAB389-(Gly4Ser)2-mIL-3.
Characterization of 3'-azido-3'-deoxythymidine inhibition of ricin and Pseudomonas exotoxin A toxicity in CHO and Vero cells.
Characterization of a cloned temperature-sensitive construct of the diphtheria toxin A domain.
Characterization of a defective diphtheria toxin repressor (dtxR) allele and analysis of dtxR transcription in wild-type and mutant strains of Corynebacterium diphtheriae.
Characterization of a full-length, active-site mutant of diphtheria toxin.
Characterization of a manganese-dependent regulatory protein, TroR, from Treponema pallidum.
Characterization of a new rice OsMADS1 null mutant generated by homologous recombination-mediated gene targeting.
Characterization of a transferrin-diphtheria toxin conjugate.
Characterization of a transgenic mouse line lacking photoreceptor development within the ventral retina.
Characterization of a transgenic mouse model of chronic conditional platelet depletion.
Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae.
Characterization of an iron-regulated promoter involved in desferrioxamine B synthesis in Streptomyces pilosus: repressor-binding site and homology to the diphtheria toxin gene promoter.
Characterization of bacteriophages from tox-containing, non-toxigenic isolates of Corynebacterium diphtheriae.
Characterization of Ca2+/calmodulin-dependent protein kinase in rat pancreatic islets.
Characterization of Cholix toxin-induced apoptosis in HeLa cells.
Characterization of complexes which contain diphtheria toxin and human nonprecipitating antitoxin.
Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor.
Characterization of diphtheria toxin's catalytic domain interaction with lipid membranes.
Characterization of diphtheria toxin-induced lesions in liposomal membranes. An evaluation of the relationship between toxin insertion and "channel" formation.
Characterization of diphtheria-toxin-resistant mutants lacking receptor function or containing nonribosylatable elongation factor 2.
Characterization of Expression of Hypothalamic Appetite-Regulating Peptides in Obese Hyperleptinemic Brown Adipose Tissue-Deficient (Uncoupling Protein-Promoter-Driven Diphtheria Toxin A) Mice* *This work was supported by a grant from Eli Lilly & Co. (to E.M.F.), NIH Grant DK-R37-28082 (to J.S.F.), and NIH Grant MH-56537 (to J.K.E.).
Characterization of expression of hypothalamic appetite-regulating peptides in obese hyperleptinemic brown adipose tissue-deficient (uncoupling protein-promoter-driven diphtheria toxin A) mice.
Characterization of high-order diphtheria toxin oligomers.
Characterization of hybrid molecules containing fragment A from diphtheria toxin linked to concanavalin A or the binding subunit of ricin toxin.
Characterization of lipoprotein IRP1 from Corynebacterium diphtheriae, which is regulated by the diphtheria toxin repressor (DtxR) and iron.
Characterization of membrane translocation by anthrax protective antigen.
Characterization of mutations that inactivate the diphtheria toxin repressor gene (dtxR).
Characterization of production processes for tetanus and diphtheria anatoxins.
Characterization of single-chain antibody (sFv)-toxin fusion proteins produced in vitro in rabbit reticulocyte lysate.
Characterization of specific nucleotide substitutions in DtxR-specific operators of Corynebacterium diphtheriae that dramatically affect DtxR binding, operator function, and promoter strength.
Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.
Characterization of the deoxyribonuclease activity of diphtheria toxin.
Characterization of the deoxyribonuclease and ADP-ribosyltransferase activities of CRM45, a truncated homologue of diphtheria toxin.
Characterization of the diphtheria toxin receptor-binding domain.
Characterization of the diphtheria toxin-resistance system in Chinese hamster ovary cells.
Characterization of the endogenous ADP-ribosylation of wild-type and mutant elongation factor 2 in eukaryotic cells.
Characterization of the insertion of Pseudomonas exotoxin A into membranes.
Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus.
Characterization of the Salmonella Typhimurium core oligosaccharide and its reducing end 3-deoxy-d-manno-oct-2-ulosonic acid used for conjugate vaccine production.
Chemical evidence for covalent linkages of a semi-synthetic glycoconjugate vaccine for Haemophilus influenzae type B disease.
Chemical modulation of diphtheria toxin action on cultured mammalian cells.
Childhood and malaria vaccines combined in biodegradable microspheres produce immunity with synergistic interactions.
Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs.
Chimeric fusion protein toxin DAB486IL-2 in advanced mycosis fungoides and the Sezary syndrome: correlation of activity and interleukin-2 receptor expression in a phase II study.
Chimeric fusion proteins used for therapy: indications, mechanisms, and safety.
Chimeric fusion proteins--diphtheria toxin-based.
Chimeric fusion proteins--Pseudomonas exotoxin-based.
Chimeric toxins: toxic, disulfide-linked conjugate of concanavalin A with fragment A from diphtheria toxin.
Chlamydia attachment to mammalian cells requires protein disulfide isomerase.
Cholesterol and the activity of bacterial toxins.
Chromogenic detection of antigen in bacteriophage plaques: a microplaque method applicable to large-scale screening.
Chromosomal assignment of the gene for human elongation factor 2.
Chromosomal organization and nucleotide sequence of the fus-gene encoding elongation factor 2 (EF-2) of the hyperthermophilic archaeum Pyrococcus woesei.
Chromosomal organization and nucleotide sequence of the genes for elongation factors EF-1 alpha and EF-2 and ribosomal proteins S7 and S10 of the hyperthermophilic archaeum Desulfurococcus mobilis.
Chromosome assignments of genes in man using mouse-human somatic cell hybrids: association of diphtheria toxin sensitivity with chromosome 5.
Chronic reactive gliosis following regulatory T cell depletion during acute MCMV encephalitis.
Chronic Stimulation of Renin Cells Leads to Vascular Pathology.
Circular dichroism of diphtheria toxin, Pseudomonas aeruginosa exotoxin A, and various derivatives.
Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.
Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin.
Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein.
Cleavage of a putative metal permease in Chlamydia trachomatis yields an iron-dependent transcriptional repressor.
Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver.
Clinical Activity and Tolerability of SL-401 (Tagraxofusp): Recombinant Diphtheria Toxin and Interleukin-3 in Hematologic Malignancies.
Clinical Experience of Treatment of Metastatic Melanoma and Solid Tumours Adopting a Derivative of Diphtheria Toxin: Cross-reacting Material 197.
Clinical Experience With Denileukin Diftitox (ONTAK).
Clinical studies of new "biologic" approaches to therapy of acute myeloid leukemia with monoclonal antibodies and immunoconjugates.
Clinical Trials and Treatment of ATL.
Clonal sector analysis and cell ablation confirm a function for DORNROESCHEN-LIKE in founder cells and the vasculature in Arabidopsis.
Cloned diphtheria toxin fragment A is expressed from the tox promoter and exported to the periplasm by the SecA apparatus of Escherichia coli K12.
Cloned diphtheria toxin within the periplasm of Escherichia coli causes lethal membrane damage at low pH.
Cloned fragment A of diphtheria toxin is expressed and secreted into the periplasmic space of Escherichia coli K12.
Cloned fragment of diphtheria toxin linked to T cell-specific antibody identifies regions of B chain active in cell entry.
Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
Cloning and expression in Escherichia coli of three fragments of diphtheria toxin truncated within fragment B.
Cloning and sequence analysis of the Corynebacterium diphtheriae dtxR homologue from Streptomyces lividans and S. pilosus encoding a putative iron repressor protein.
Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa.
Cloning, nucleotide sequence, and hybridization studies of the type IIb heat-labile enterotoxin gene of Escherichia coli.
Cloning, sequence determination, and expression in transfected cells of the coding sequence for the tox 176 attenuated diphtheria toxin A chain.
Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron.
Co-assembled Ca2+ Alginate-Sulfate Nanoparticles for Intracellular Plasmid DNA Delivery.
Coagglutination for rapid testing of toxin producing Corynebacterium diphtheriae.
Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis.
Codominant translational mutants of Chinese hamster ovary cells selected with diphtheria toxin.
Collaborative study for establishment of the European Pharmacopoeia BRP batch 1 for diphtheria toxin.
Combination of DTP and Haemophilus influenzae type b conjugate vaccines can affect laboratory evaluation of potency and immunogenicity.
Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation.
Combinations of protein polysaccharide conjugate vaccines for intranasal immunization.
Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea.
Combined prokaryotic-eukaryotic delivery and expression of therapeutic factors through a primed autocatalytic positive-feedback loop.
Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins.
Comparative genomic analysis between Corynebacterium pseudotuberculosis strains isolated from buffalo.
Comparative genomic and phylogenetic analysis of a toxigenic clinical isolate of Corynebacterium diphtheriae strain B-D-16-78 from Malaysia.
Comparative proteomics of the Mycobacterium leprae binding protein myelin P0: its implication in leprosy and other neurodegenerative diseases.
Comparative seroepidemiology of diphtheria in six European countries and Israel.
COMPARATIVE STATISTICS OF ANTITOXIN HORSES. A STUDY OF THE RECORDS OF ONE HUNDRED HORSES IMMUNIZED TO DIPHTHERIA TOXIN, WITH COMPOSITE OF CURVES.
Comparative Structural Analysis of the Putative Mono-ADP-Ribosyltransferases of the ARTD/PARP Family.
Comparative study of transplantation of hepatocytes at various differentiation stages into mice with lethal liver damage.
Comparison o the peptide "finger print" and antigenic specificity of a diphtheria toxin fragment produced by a phage-mutant lysogen and "fragments A and B" of the toxin.
Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age.
Comparison of CRM197, diphtheria toxoid and tetanus toxoid as protein carriers for meningococcal glycoconjugate vaccines.
Comparison of diphtheria intoxication in human and nonhuman cell lines and their resistant variants.
Comparison of four serological methods for the detection of diphtheria anti-toxin antibody.
Comparison of gel filtration and ammonium sulphate precipitation in the purification of diphtheria toxin and toxoid.
Comparison of high-resolution structures of the diphtheria toxin repressor in complex with cobalt and zinc at the cation-anion binding site.
Comparison of membrane insertion pathways of the apoptotic regulator Bcl-xL and the diphtheria toxin translocation domain.
Comparison of methods for purification of diphtheria toxin with special reference to gelfiltration and ion-exchange chromatography.
Comparison of phenotypic and genotypic methods for detection of diphtheria toxin among isolates of pathogenic corynebacteria.
Comparison of protein synthesis inhibition kinetics and cell killing induced by immunotoxins.
Comparison of serum bactericidal and antibody titers induced by two Haemophilus influenzae type b conjugate vaccines: A phase III randomized double-blind study.
Comparison of seven commercial enzyme-linked immunosorbent assays for the detection of anti-diphtheria toxin antibodies.
Comparison of the apoptosis-inducing abilities of various protein synthesis inhibitors in U937 cells.
Comparison of the conformation, hydrophobicity, and model membrane interactions of diphtheria toxin to those of formaldehyde-treated toxin (diphtheria toxoid): formaldehyde stabilization of the native conformation inhibits changes that allow membrane insertion.
Comparison of the diphtheria mutant toxin, CRM197, with a Haemophilus influenzae type-b polysaccharide-CRM197 conjugate by optical spectroscopy.
Comparison of the frequency of diphtheria toxin and thioguanine resistance induced by a series of carcinogens to analyze their mutational specificities in diploid human fibroblasts.
Comparison of the guinea pig and chick in evaluation of diphtheria toxin for the Schick test.
Comparison of the intoxication pathways of tumor necrosis factor and diphtheria toxin.
Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage.
Competitive antagonists of the action of diphtheria toxin in HeLa cells.
Competitive binding of adenine and nicotinamide-adenine dinucleotide to diphtheria toxin.
Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement.
Complete nucleotide sequence and characterization of the 5'-flanking region of mammalian elongation factor 2 gene.
Computer modelling of the NAD binding site of ADP-ribosylating toxins: active-site structure and mechanism of NAD binding.
Computer modelling of the transmembrane channel formed by a CNBr peptide of diphtheria toxin B fragment.
Concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin T domain.
Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4-Positive Cancer Cell Population.
Concomitant administration of diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) with pentavalent rotavirus vaccine in Japanese infants.
Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons.
Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes.
Conditional ablation of macrophages disrupts ovarian vasculature.
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis.
Conditional ablation of mature olfactory sensory neurons mediated by diphtheria toxin receptor.
Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function.
Conditional cell ablation via diphtheria toxin reveals distinct requirements for the basal plate in the regional identity of diencephalic subpopulations.
Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE.
Conditional Depletion of Airway Progenitor Cells Induces Peribronchiolar Fibrosis.
Conditional lineage ablation to model human diseases.
Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation.
Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors.
Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth.
Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration.
Conformation and model membrane interactions of diphtheria toxin fragment A.
Conformation of diphtheria toxin and an enzymically-active fragment.
Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop.
Conformational changes in BID, a pro-apoptotic BCL-2 family member, upon membrane binding. A site-directed spin labeling study.
Conformational changes in diphtheria toxoids. Analysis with monoclonal antibodies.
Conformational changes of the ferric uptake regulation protein upon metal activation and DNA binding; first evidence of structural homologies with the diphtheria toxin repressor.
Conformational switching of the diphtheria toxin T domain.
Conformational switching, refolding and membrane insertion of the diphtheria toxin translocation domain.
Connexin 36 in photoreceptor cells: studies on transgenic rod-less and cone-less mouse retinas.
Consequences of early life overfeeding for microglia - Perspectives from rodent models.
Conservation of a common motif in enzymes catalyzing ADP-ribose transfer. Identification of domains in mammalian transferases.
Conserved Structural Motif for Recognizing Nicotinamide Adenine Dinucleotide in Poly(ADP-ribose) Polymerases and ADP-Ribosylating Toxins: Implications for Structure-Based Drug Design.
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity.
Construction and characterization of transposon insertion mutations in Corynebacterium diphtheriae that affect expression of the diphtheria toxin repressor (DtxR).
Construction and expression in Escherichia coli of hybrid genes composed of sequences encoding diphtheria toxin and human CD4 receptor.
Construction and expression of diphtheria toxin-encoding gene derivatives in Escherichia coli.
Construction and expression of plasmids containing mutated diphtheria toxin A-chain-coding sequences.
Construction and preliminary investigation of a plasmid containing a novel immunotoxin DT390-IL-18 gene for the prevention of murine experimental autoimmune encephalomyelitis.
Construction of a diphtheria toxin A fragment-C180 peptide fusion protein which elicits a neutralizing antibody response against diphtheria toxin and pertussis toxin.
Construction of a toxic insulin molecule: selection and partial characterization of cells resistant to its killing effects.
Construction of an epitope vector utilising the diphtheria toxin B-subunit.
Construction of viable mouse-human hybrid cells by nuclear transplantation.
Contractility and ultrastructure of cardiac muscle of guinea pigs treated with diphtheria toxin.
Contribution of plasminogen activator urokinase to in vitro cytotoxicity of diphtheria toxin.
Control of axillary bud growth in tobacco through toxin gene expression system.
Cooperation between heparin-binding EGF-like growth factor and interleukin-6 in promoting the growth of human myeloma cells.
Coordinate regulation of siderophore and diphtheria toxin production by iron in Corynebacterium diphtheriae.
COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.
Cornea-infiltrating and lymph node dendritic cells contribute to CD4+ T cell expansion after herpes simplex virus-1 ocular infection.
Correct patterning of the primitive streak requires the anterior visceral endoderm.
Correlation of cytotoxicity with elimination of iodine-125 from nude mice inoculated with prelabeled human melanoma cells.
Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages.
Cortical plasticity induced by transplantation of embryonic somatostatin or parvalbumin interneurons.
Corynebacterium argentoratense sp. nov., from the human throat.
Corynebacterium diphtheriae Infection in Mahajanga, Madagascar: First Case Report.
Corynebacterium diphtheriae Virulence Analyses Using a Caenorhabditis elegans Model.
Corynebacterium diphtheriae: Diphtheria Toxin, the tox Operon, and Its Regulation by Fe2+ Activation of apo-DtxR.
Corynebacterium epidermidicanis sp. nov., isolated from a dog's skin.
Corynebacterium hindlerae sp. nov., derived from a human granuloma, which forms black colonies and black halos on modified Tinsdale medium but is not closely related to Corynebacterium diphtheriae and related taxa.
Corynebacterium imitans sp. nov. isolated from patients with suspected diphtheria.
Corynebacterium pyruviciproducens promotes the production of ovalbumin specific antibody via stimulating dendritic cell differentiation and up-regulating Th2 biased immune response.
Corynebacterium pyruviciproducens, as an immune modulator, can promote the activity of macrophages and up-regulate antibody response to particulate antigen.
Corynebacterium rouxii sp. nov., a novel member of the diphtheriae species complex.
Corynebacterium rouxii, a recently described member of the C. diphtheriae group isolated from three dogs with ulcerative skin lesions.
Corynebacterium ulcerans 0102 carries the gene encoding diphtheria toxin on a prophage different from the C. diphtheriae NCTC 13129 prophage.
Corynebacterium ulcerans and Corynebacterium pseudotuberculosis responses to DNA probes derived from corynephage beta and Corynebacterium diphtheriae.
Corynebacterium ulcerans from Diseased Wild Boars.
Corynebacterium ulcerans Isolated from an Asymptomatic Dog Kept in an Animal Shelter in the Metropolitan Area of Rio de Janeiro, Brazil.
Cost-benefit analysis of Haemophilus influenzae type b prevention: conjugate vaccination at eighteen months of age.
Cotranslational secretion of diphtheria toxin and alkaline phosphatase in vitro: involvement of membrane protein(s).
Creation of intercellular bonds by anchoring protein ligands to membranes using the diphtheria toxin T domain.
CreER(T2) expression from within the c-Kit gene locus allows efficient inducible gene targeting in and ablation of mast cells.
Critical appraisal of a quadrivalent CRM(197) conjugate vaccine against meningococcal serogroups A, C W-135 and Y (Menveo) in the context of treatment and prevention of invasive disease.
Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens.
Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1.
Critical roles of regulatory B and T cells in helminth parasite-induced protection against allergic airway inflammation.
CRM197 (nontoxic diphtheria toxin): effects on advanced cancer patients.
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
CRM197-induced blood-brain barrier permeability increase is mediated by upregulation of caveolin-1 protein.
Cross-dressed dendritic cells drive memory CD8(+) T-cell activation after viral infection.
Cross-reacting material 197 (CRM197) affects actin cytoskeleton of endothelial cells.
Crucial Role of H322 in Folding of the Diphtheria Toxin T-Domain into the Open-Channel State.
Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli.
Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae.
Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide.
Crystal Structure of Exotoxin A from Aeromonas Pathogenic Species.
Crystal structure of human ADP-ribose transferase ARTD15/PARP16 reveals a novel putative regulatory domain.
Crystal structure of nucleotide-free diphtheria toxin.
Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation.
Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor.
Crystal structure of the cyanobacterial metallothionein repressor SmtB: a model for metalloregulatory proteins.
Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied.
Crystallization and preliminary X-ray diffraction analysis of the metalloregulatory protein DtxR from Thermoplasma acidophilum.
Crystallization and preliminary X-ray studies of the diphtheria Tox repressor from Corynebacterium diphtheriae.
Crystallization of diphtheria toxin.
Cure of experimental human malignant mesothelioma in athymic mice by diphtheria toxin.
Cutaneous ulcers revealing diphtheria: A re-emerging disease imported from Indian Ocean countries?
Cutting edge: dendritic cells are essential for in vivo IL-12 production and development of resistance against Toxoplasma gondii infection in mice.
Cutting edge: depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice.
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells.
Cytoplasmic complex of p53 and eEF2.
Cytoplasmic inhibitor of eEF-2 ADP-ribosylation catalyzed by diphtheria toxin or endogenous transferase in rat liver cells.
Cytoreductive effects of anti-transferrin receptor immunotoxin in a multicellular tumor spheroid model.
Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.
Cytotoxic activity of a recombinant chimaeric protein between Pseudomonas aeruginosa exotoxin A and Corynebacterium diphtheriae diphtheria toxin.
Cytotoxic and mutagenic properties of shale oil byproducts II. Comparison of mutagenic effects at five genetic markers induced by retort process water plus near ultraviolet light in Chinese hamster ovary cells.
Cytotoxic effect of diphtheria toxin used alone or in combination with other agents on human renal cell carcinoma cell lines.
Cytotoxic properties of DAB486EGF and DAB389EGF, epidermal growth factor (EGF) receptor-targeted fusion toxins.
Cytotoxicity and specificity of directed toxins composed of diphtheria toxin and the EGF-like domain of heregulin beta1.
Cytotoxicity of a hybrid prepared by coupling diphtheria toxin A-chain with immunoglobulin Fab' with N,N'-o-phenylenedimaleimide.
Cytotoxicity of a novel fibroblast growth factor receptor targeted immunotoxin on a human ovarian teratocarcinoma cell line.
Cytotoxicity of a recombinant diphtheria toxin-granulocyte colony-stimulating factor fusion protein on human leukemic blast cells.
Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence.
Cytotoxicity of diphtheria toxin A fragment to toxin-resistant murine cells delivered by pH-sensitive immunoliposomes.
DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology.
DAB(389)IL-2 (ONTAK): a novel fusion toxin therapy for lymphoma.
DAB389EGF fusion protein therapy of refractory glioblastoma multiforme.
DAB389IL-2 suppresses autoimmune inflammation in the CNS and inhibits T cell-mediated lysis of glial target cells.
DAB486IL-2 fusion toxin in refractory rheumatoid arthritis.
DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses.
DC ablation in mice: promises, pitfalls, and challenges.
De novo maintenance therapy with denileukin diftitox (Ontak) in a patient with peripheral T-cell lymphoma is associated with prolonged remission.
Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy.
Decreased Sensitivity to Changes in the Concentration of Metal Ions as the Basis for the Hyperactivity of DtxR(E175K).
Decreased sensitivity to diphtheria toxin of Vero cells cultured in serum-free medium.
Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses.
Defining in vivo dendritic cell functions using CD11c-DTR transgenic mice.
Defining the cell lineages of the islets of Langerhans using transgenic mice.
Degradation of ricin A chain by endosomal and lysosomal enzymes--the protective role of ricin B chain.
Degrees of susceptibility to Diphtheria Toxin among Guinea-Pigs. Transmission from Parents to Offspring.
Delayed hypersensitivity. I. Induction of hypersensitivity to diphtheria toxin in guinea pigs by infection with Corynebacterium diphtheriae.
Deletion of Foxp3+ regulatory T cells in genetically targeted mice supports development of intestinal inflammation.
Deletion of psbQ' gene in Cyanidioschyzon merolae reveals the function of extrinsic PsbQ' in PSII.
Deletion of TLR2+ erythro-myeloid progenitors leads to embryonic lethality in mice.
Delivery into cells: lessons learned from plant and bacterial toxins.
Delivery of a stringent dimerizer-regulated gene expression system in a single retroviral vector.
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process.
DeltaNp73 regulates neuronal survival in vivo.
Demonstration of diphtheria toxin receptors on surface membranes from both toxin-sensitive and toxin-resistant species.
Demyelination and remyelination in the rat central nervous system following ethidium bromide injection.
Demyelination following diphtheria toxin in the presence of axonal atrophy.
Demyelination of Sternarchus electrocyte fibers by injection of diphtheria toxin.
Dendritic cell-epithelium interplay is a determinant factor for corneal epithelial wound repair.
Dendritic cells and alveolar macrophages mediate IL-13-induced airway inflammation and chemokine production.
Dendritic cells are crucial for cardiovascular remodeling and modulate neutrophil gelatinase-associated lipocalin expression upon mineralocorticoid receptor activation.
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Dendritic cells are required for effective cross-presentation in the murine liver.
Dendritic cells modulate burn wound healing by enhancing early proliferation.
Dendritic cells play a role in host susceptibility to Cryptosporidium parvum infection.
Dendritic Cells Promote Pancreatic Viability in Mice with Acute Pancreatitis.
Dendritic cells support a proliferative antigen-specific T-cell response in the presence of poly(lactic-co-glycolic acid).
Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice.
Denileukin Diftitox (Ontak) as Maintenance Therapy for Peripheral T-Cell Lymphomas: Three Cases with Sustained Remission.
Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg.
Denileukin diftitox for the treatment of steroid-resistant acute graft-versus-host disease.
Denileukin diftitox.
Denileukin diftitox: a biotherapeutic paradigm shift in the treatment of lymphoid-derived disorders.
Denileukin diftitox: a concise clinical review.
Depleting hypothalamic somatostatinergic neurons recapitulates diabetic phenotypes in mouse brain, bone marrow, adipose and retina.
Depletion of alveolar macrophages in CD11c diphtheria toxin receptor mice produces an inflammatory response.
Depletion of CD11c(+) cells in the CD11c.DTR model drives expansion of unique CD64(+) Ly6C(+) monocytes that are poised to release TNF-?.
Depletion of cells of monocyte lineage prevents loss of renal microvasculature in murine kidney transplantation.
Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury.
Depletion of Foxp3+ regulatory T cells is accompanied by an increase in the relative abundance of Firmicutes in the murine gut microbiome.
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Depletion of intracellular NAD(+) and ATP levels during ricin-induced apoptosis through the specific ribosomal inactivation results in the cytolysis of U937 cells.
Depletion of macrophages and dendritic cells in ischemic acute kidney injury.
Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.
Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum.
Depletion of Neural Crest-Derived Cells Leads to Reduction in Plasma Noradrenaline and Alters B Lymphopoiesis.
Depletion of regulatory T cells augments a vaccine-induced T effector cell response against the liver-stage of malaria but fails to increase memory.
Depletion of regulatory T cells in ongoing paracoccidioidomycosis rescues protective Th1/Th17 immunity and prevents fatal disease outcome.
Depletion of regulatory T cells increases T cell brain infiltration, reactive astrogliosis, and interferon-? gene expression in acute experimental traumatic brain injury.
Depletion of regulatory T cells leads to an exacerbation of delayed-type hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade.
Design and development of a novel genetic probe for the analysis of repressor-operator interactions.
Design and engineering of tumor-targeted, dual-acting cytotoxic nanoparticles.
Design of a Cytotoxic Neuroblastoma-Targeting Agent Using an Enzyme Acting on Polysialic Acid Fused to a Toxin.
Design of Glycoconjugate Vaccines against Invasive African Salmonella enterica Serovar Typhimurium.
Design of highly specific cytotoxins by using trans-splicing ribozymes.
Design, characterization and anti-tumour cytotoxicity of a panel of recombinant, mammalian ribonuclease-based immunotoxins.
Detection and Characterization of Diphtheria Toxin Gene-Bearing Corynebacterium Species through a New Real-Time PCR Assay.
Detection and expression of DNA homologous to the tox gene in nontoxinogenic isolates of Corynebacterium diphtheriae.
Detection and organ-specific ablation of neuroendocrine cells by synaptophysin locus-based BAC cassette in transgenic mice.
Detection of arginine-ADP-ribosylated protein using recombinant ADP-ribosylarginine hydrolase.
Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections.
Detection of diphtheria toxin antibodies in human sera in New Zealand by ELISA.
Detection of diphtheria toxin in culture supernates of Corynebacterium diphtheriae and C. ulcerans by immunoassay with monoclonal antibody.
Detection of DNA damage in prokaryotes by terminal deoxyribonucleotide transferase-mediated dUTP nick end labeling.
Detection of toxin-producing Corynebacterium diphtheriae from throat swabs of diphtheria patients using duplex real-time PCR.
Determination of Corynebacterium diphtheriae toxigenicity by a colorimetric tissue culture assay.
Determination of cytotoxicity in vivo using 111indium-labeled human tumor cells.
Determination of diphtheria toxin neutralizing antibody titers with a cell protein synthesis inhibition assay.
Determination of free polysaccharide in Vi glycoconjugate vaccine against typhoid fever.
Determination of the minimal essential nucleotide sequence for diphtheria tox repressor binding by in vitro affinity selection.
Determination of the presence of diphtheria toxin in the myocardial tissue of rabbits and a female subject by using an immunofluorescent antibody method.
Detoxification of diphtheria toxin by peroxidase.
Detoxification of diphtheria toxin with formaldehyde mixed with an amino-acid.
Development and clinical testing of an acellular pertussis vaccine containing genetically detoxified pertussis toxin.
Development and patterning of rib primordia are dependent on associated musculature.
Development and phase 1 clinical testing of a conjugate vaccine against meningococcus A and C.
Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus.
Development of a biological test to evaluate the bioavailability of iron in culture media.
Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies.
Development of a diphtheria toxin based anti-porcine CD3 recombinant immunotoxin.
Development of a diphtheria toxin mutant conjugate directed against antigen-specific B cells expressing high affinity surface Ig.
Development of a diphtheria toxin-based recombinant porcine IL-2 fusion toxin for depleting porcine CD25(+) cells.
Development of a direct PCR assay for detection of the diphtheria toxin gene.
Development of a nonintegrating Rev-dependent lentiviral vector carrying diphtheria toxin A chain and human TRAF6 to target HIV reservoirs.
Development of a novel molecular adapter for the optimization of immunotoxins.
Development of a real-time fluorescence PCR assay for rapid detection of the diphtheria toxin gene.
Development of a recombinant immunotoxin for the immunotherapy of autoreactive lymphocytes expressing MOG-specific BCRs.
Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells.
Development of human monoclonal antibodies to diphtheria toxin: A solution for the increasing lack of equine DAT for therapeutic use?
Development of novel O-polysaccharide based glycoconjugates for immunization against glanders.
Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for a broad spectrum of solid tumors mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P4 and IGF2-P3 regulatory sequences.
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P3 and IGF2-P4 regulatory sequences.
Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences.
Development of Vi conjugate - a new generation of typhoid vaccine.
Development, validation and implementation of a quadruplex real-time PCR assay for identification of potentially toxigenic corynebacteria.
Developmental analysis of ocular morphogenesis in alpha A-crystallin/diphtheria toxin transgenic mice undergoing ablation of the lens.
Developmental regulation for collagen II gene expression in transgenic mice.
Diacytosis of asialoglycoprotein in isolated hepatocytes is dependent on the structure of ligand and cellular distribution of the receptors.
Differences in the avidity of antibodies evoked by four different pneumococcal conjugate vaccines in early childhood.
Differences in the immunogenicity of native and formalinized cross reacting material (CRM197) of diphtheria toxin in mice and guinea pigs and their implications on the development and control of diphtheria vaccine based on CRMs.
Differences in the immunogenicity of three Haemophilus influenzae type b conjugate vaccines in infants.
Different sensitivity of Pseudomonas aeruginosa exotoxin A and diphtheria toxin to enzymes from polymorphonuclear leukocytes.
Different Temporal and Spatial Gene Expression Patterns Occur during Anther Development.
Differential effects of denileukin diftitox IL-2 immunotoxin on NK and regulatory T cells in nonhuman primates.
Differential manifestation of seed mortality induced by seed-specific expression of the gene for diphtheria toxin A chain in Arabidopsis and tobacco.
Differential mRNA transport and the regulation of protein synthesis: selective sensitivity of Purkinje cell dendritic mRNAs to translational inhibition.
Differential potencies of effector genes in adult Drosophila.
Differential potency of regulatory T cell-mediated immunosuppression in kidney tumors compared to subcutaneous tumors.
Differential sensitivity of reticulocytes to nicked and unnicked diphtheria toxin.
Differential toxicity of ricin and diphtheria toxin for bloodstream forms of Trypanosoma brucei.
Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis.
Diisopropylfluorophosphate (DFP) inhibits ricin-induced apoptosis of MDCK cells.
Dimeric form of diphtheria toxin: purification and characterization.
Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.
Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development.
Diphtheria fusion protein therapy of chemoresistant malignancies.
Diphtheria in the United States, 1971-81.
Diphtheria Pathogenesis in Guinea Pig Tracheal Organ Culture.
Diphtheria toxin A gene-mediated HIV-1 protection of cord blood-derived T cells in the SCID-hu mouse model.
Diphtheria Toxin A-Resistant Cell Lines Enable Robust Production and Evaluation of DTA-Encoding Lentiviruses.
Diphtheria toxin and antitoxin; a short of progress since the work of Ehrlich.
Diphtheria toxin and its ADP-ribosyltransferase-defective homologue CRM197 possess deoxyribonuclease activity.
Diphtheria toxin and its mutant crm 197 differ in their interaction with lipids.
Diphtheria toxin and mutant proteins.
Diphtheria toxin and Pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism.
Diphtheria toxin and related proteins. 3. Reconstitution of hybrid "diphtheria toxin" from nontoxic mutant proteins.
Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin.
Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins.
Diphtheria toxin and related proteins: effect of route of injection on toxicity and the determination of cytotoxicity for various cultured cells.
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling.
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells.
Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity.
Diphtheria toxin can be used as a vehicle for bringing other proteins into cells.
Diphtheria toxin can simultaneously bind to its receptor and adenylyl-(3',5')-uridine 3'-monophosphate.
Diphtheria toxin catalyzed hydrolysis of NAD(+): molecular dynamics study of enzyme-bound substrate, transition state, and inhibitor.
Diphtheria toxin cloning and expression in Corynebacterium diphtheriae.
Diphtheria toxin conformational switching at acidic pH.
Diphtheria toxin conjugate therapy of cancer.
Diphtheria toxin does not enter resistant cells by receptor-mediated endocytosis.
Diphtheria toxin effects on brain-tumor xenografts. Implications for protein-based brain-tumor chemotherapy.
Diphtheria toxin effects on human cells in tissue culture.
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells.
Diphtheria toxin entry into cells is facilitated by low pH.
Diphtheria toxin entry: protein translocation in the reverse direction.
Diphtheria toxin expression in Escherichia coli.
Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization.
Diphtheria toxin forms transmembrane channels in planar lipid bilayers.
Diphtheria Toxin Fragment Channels in Lipid Bilayer Membranes: Selective Sieves of Discarded Wrappers?
Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor and Ara-C exert synergistic toxicity against human AML HL-60 cells.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias.
Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of blasts from patients with acute myeloid leukemia according to the level of interleukin-3 receptor expression.
Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.
Diphtheria toxin fusion proteins.
Diphtheria toxin has the properties of a lectin.
Diphtheria toxin IgG levels in military and civilian blood donors in Rio de Janeiro, Brazil.
Diphtheria toxin induces fusion of small unilamellar vesicles at low pH.
Diphtheria toxin induces leakage of acidic liposomes.
Diphtheria toxin inhibits the synthesis of myelin proteolipid and basic proteins by peripheral nerve in vitro.
Diphtheria toxin mutant CRM197 is an inhibitor of protein synthesis that induces cellular toxicity.
Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.
Diphtheria Toxin Mutant CRM197-Mediated Transcytosis across Blood-Brain Barrier In Vitro.
Diphtheria toxin mutant selectively kills cerebellar Purkinje neurons.
Diphtheria toxin NAD affinity and ADP ribosyltransferase activity are reduced at tryptophan 153 substitutions for alanine or phenylalanine.
Diphtheria toxin prevents catecholamine desensitization of A431 human epidermoid carcinoma cells.
Diphtheria toxin production by Corynebacterium ulcerans from cats.
Diphtheria toxin promoter function in Corynebacterium diphtheriae and Escherichia coli.
Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein.
Diphtheria toxin receptor sites on membranes of cultured cells and erythrocytes demonstrated by fluorescence and electron microscopy.
Diphtheria toxin receptor-binding domain substitution with interleukin 6: genetic construction and interleukin 6 receptor-specific action of a diphtheria toxin-related interleukin 6 fusion protein.
Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice.
Diphtheria toxin receptor. Identification of specific diphtheria toxin-binding proteins on the surface of Vero and BS-C-1 cells.
Diphtheria toxin resistance in Chinese hamster cells: genetic and biochemical characteristics of the mutants affected in protein synthesis.
Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals.
Diphtheria toxin resistance in human lymphoblast lines.
Diphtheria toxin resistance in human lymphocytes and lymphoblasts in the in vivo somatic cell mutation test.
Diphtheria toxin sensitivity in a monochromosomal hybrid containing human chromosome 5.
Diphtheria toxin subunit active in vitro.
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids.
Diphtheria toxin translocation across endosome membranes. A novel cell permeabilization assay reveals new diphtheria toxin fragments in endocytic vesicles.
Diphtheria toxin treatment of human advanced cancer.
Diphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception.
Diphtheria toxin, protein synthesis, and the cell.
Diphtheria Toxin- and GFP-Based Mouse Models of Acquired Hypoparathyroidism and Treatment with a Long-Acting Parathyroid Hormone Analog.
Diphtheria toxin- and Pseudomonas A toxin-mediated apoptosis. ADP ribosylation of elongation factor-2 is required for DNA fragmentation and cell lysis and synergy with tumor necrosis factor-alpha.
Diphtheria toxin-based targeted toxin therapy for brain tumors.
Diphtheria toxin-binding glycoproteins on hamster cells: candidates for diphtheria toxin receptors.
Diphtheria toxin-epidermal growth factor fusion protein DAB389EGF for the treatment of bladder cancer.
Diphtheria toxin-induced autophagic cardiomyocyte death plays a pathogenic role in mouse model of heart failure.
Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice.
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations.
Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice.
Diphtheria toxin-mediated ablation of parietal cells in the stomach of transgenic mice.
Diphtheria toxin-mediated cell ablation reveals interregional communication during Arabidopsis seed development.
Diphtheria toxin-mediated transposon-driven poly (A)-trapping efficiently disrupts transcriptionally silent genes in embryonic stem cells.
Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor-induced hepatotoxicity is mediated by Kupffer cells.
Diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion toxin. Internal in-frame deletion from Thr387 to His485 results in the formation of a highly potent fusion toxin which is resistant to proteolytic degradation.
Diphtheria toxin-related cytokine fusion proteins: elongation factor 2 as a target for the treatment of neoplastic disease.
Diphtheria toxin-resistant mutants of Saccharomyces cerevisiae.
Diphtheria toxin.
Diphtheria toxin. Effect of substituting aspartic acid for glutamic acid 148 on ADP-ribosyltransferase activity.
Diphtheria toxin. Site and configuration of ADP-ribosylation of diphthamide in elongation factor 2.
Diphtheria Toxin/Human B-Cell Activating Factor Fusion Protein Kills Human Acute Lymphoblastic Leukemia BALL-1 Cells: An Experimental Study.
Diphtheria toxin: evidence for presence of fragment B in corynebacteriophage.
Diphtheria toxin: membrane interaction and membrane translocation.
Diphtheria toxin: mode of action and structure.
Diphtheria toxin: nucleotide binding and toxin heterogeneity.
Diphtheria toxin: purification and properties.
Diphtheria toxin: quantification and assay.
Diphtheria toxin: requirement for active protein synthesis for inactivation of aminoacyl transferase II in the intact mammalian cell.
Diphtheria toxin: specific competition for cell receptors.
Diphtheria toxin: the effect of nitration and reductive methylation on enzymatic activity and toxicity.
Diphtheria toxin: which route into the cell?
Diphtheria toxin:receptor interaction: association, dissociation, and effect of pH.
Diphtheria toxin; a comparison between the diphtherial succinoxidase system and that of beef heart muscle.
Diphtheria toxin; a reinvestigation of the effect of iron on toxin and porphyrin production.
Diphtheria toxin; the iron enzymes of Corynebacterium diphtheriae and their possible relation to diphtheria toxin.
Diphtheria, tetanus and pertussis antibodies in 10-year-old children before and after a booster dose of three toxoids: implications for the timing of a booster dose.
Diphtheria-related peptide hormone gene fusions: a molecular genetic approach to chimeric toxin development.
Diphtheria-toxin-resistant mutants of CHO cells affected in protein synthesis: a novel phenotype.
Diphtheria.
Diphtheric encephalitis and brain neuroimaging features.
Diphtheritic angina in the tongue and floor of the mouth: unusual presentation.
Direct polymerase chain reaction for detection of toxigenic Corynebacterium diphtheriae strains from the Republic of Georgia after prolonged storage.
Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin.
Directly transfected langerin+ dermal dendritic cells potentiate CD8+ T cell responses following intradermal plasmid DNA immunization.
Discovery of novel bacterial toxins by genomics and computational biology.
Disease caused by Haemophilus influenzae type b in the immediate period after homologous immunization: immunologic investigation.
Disordered to ordered folding in the regulation of diphtheria toxin repressor activity.
Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing.
Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin.
Distinct effects of dipeptidyl peptidase-4 inhibitor and glucagon-like peptide-1 receptor agonist on islet morphology and function.
Distinct Genomic Features Characterize Two Clades of Corynebacterium diphtheriae: Proposal of Corynebacterium diphtheriae Subsp. diphtheriae Subsp. nov. and Corynebacterium diphtheriae Subsp. lausannense Subsp. nov.
Distinct Role of CD11b+Ly6G-Ly6C- Myeloid-Derived Cells on the Progression of the Primary Tumor and Therapy-Associated Recurrent Brain Tumor.
Distribution of endocytosed molecules to intracellular acidic environments correlates with immunotoxin activity.
Dithizone-induced Paneth cell disruption significantly decreases intestinal perfusion in the murine small intestine.
Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues.
DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis.
DNA methyltransferase inhibition overcomes diphthamide pathway deficiencies underlying CD123-targeted treatment resistance.
DNA nanotherapy for pre-neoplastic cervical lesions.
Does diphtheria toxin have nuclease activity?
Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain.
Domain analysis of the tetraspanins: studies of CD9/CD63 chimeric molecules on subcellular localization and upregulation activity for diphtheria toxin binding.
Domain swapping: entangling alliances between proteins.
Dominant inhibition of lens placode formation in mice.
Donor antioxidant strategy prolongs cardiac allograft survival by attenuating tissue dendritic cell immunogenicity(†).
Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants.
Dose response of CRM197 and tetanus toxoid-conjugated Haemophilus influenzae type b vaccines.
Double-antibody sandwich enzyme-linked immunosorbent assay for rapid detection of toxin-producing Corynebacterium diphtheriae.
DPH1 syndrome: two novel variants and structural and functional analyses of seven missense variants identified in syndromic patients.
Dph3 is an electron donor for Dph1-Dph2 in the first step of eukaryotic diphthamide biosynthesis.
Dph3, a small protein required for diphthamide biosynthesis, is essential in mouse development.
DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae.
DR2539 is a novel DtxR-like regulator of Mn/Fe ion homeostasis and antioxidant enzyme in Deinococcus radiodurans.
Draft Genome Sequences of Two Toxigenic Corynebacterium ulcerans Strains.
DT(270-326) , a Truncated Diphtheria Toxin, Increases Blood-Tumor Barrier Permeability by Upregulating the Expression of Caveolin-1.
DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
DT390-triTMTP1, a novel fusion protein of diphtheria toxin with tandem repeat TMTP1 peptide, preferentially targets metastatic tumors.
DTA-mediated targeted ablation revealed differential interdependence of endocrine cell lineages in early development of zebrafish pancreas.
DTR-mediated conditional cell ablation-Progress and challenges.
Dual effects of the ricin A chain on protein synthesis in rabbit reticulocyte lysate. Inhibition of initiation and translocation.
Dual mode of signal transduction by externally added acidic fibroblast growth factor.
Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells.
Duct Cells Contribute to Regeneration of Endocrine and Acinar Cells Following Pancreatic Damage in Adult Mice.
Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response.
Dwarf mice produced by genetic ablation of growth hormone-expressing cells.
Dynamic transitions of the transmembrane domain of diphtheria toxin: disulfide trapping and fluorescence proximity studies.
Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.
Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury.
E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T-cell lymphoma: A phase I study.
Early acceptance of renal allografts in mice is dependent on foxp3(+) cells.
Early direct and transneuronal effects in mice with targeted expression of a toxin gene to D1 dopamine receptor neurons.
Early microvascular complications of prediabetes in mice with impaired glucose tolerance and dyslipidemia.
Early responding dendritic cells direct the local NK response to control herpes simplex virus 1 infection within the cornea.
Ectodomain shedding of HB-EGF: a potential target for cancer therapy.
Ectopic activity in demyelinated spinal root axons of the rat.
Ectopic Noggin in a Population of Nfatc1 Lineage Endocardial Progenitors Induces Embryonic Lethality.
Effect of adenine and nicotinamide on amino acid incorporation of cell-free systems inhibited by diphtheria toxin and NAD.
Effect of ADP-ribosylation and phosphorylation on the interaction of elongation factor 2 with guanylic nucleotides.
Effect of ammonium chloride on receptor-mediated uptake of diphtheria toxin by Vero cells.
Effect of antioxidants on mutagenesis induced by DMBA in human cells.
Effect of carrier protein priming on antibody responses to Haemophilus influenzae type b conjugate vaccines in infants.
Effect of DAB(389)IL-2 immunotoxin on the course of experimental autoimmune encephalomyelitis in Lewis rats.
Effect of diphtheria toxin on lysosome activity in leukocytes and Ehrlich ascites tumor cells.
Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors.
Effect of diphtheria toxin on the metabolism of animal tissues and tissue cultures.
EFFECT OF DIPHTHERIA TOXIN ON THE UTILISATION OF SINGLE CARBON SOURCES BY KLEBSIELLA AEROGENES.
EFFECT OF DIPHTHERIA TOXIN T-DOMAIN ON ENDOSOMAL pH.
Effect of diphtheria toxin upon tissue enzymes in vitro.
Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma.
Effect of diphtheritic demyelination on axonal transport in the sciatic nerve and subsequent muscle changes in the chicken.
Effect of electroporation-mediated diphtheria toxin A expression on PSA positive human prostate xenograft tumors in SCID mice.
Effect of energy inhibitors on cell surface diphtheria toxin receptor numbers.
Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen.
Effect of Haemophilus influenzae polysaccharide outer membrane protein complex conjugate vaccine on macrophages.
Effect of helicobacter pylori vacuolating toxin on maturation and extracellular release of procathepsin D and on epidermal growth factor degradation.
Effect of immunity to the carrier protein on antibody responses to Haemophilus influenzae type b conjugate vaccines.
Effect of Lactobacillus johnsonii La1 on immune function and serum albumin in aged and malnourished aged mice.
Effect of lovastatin on the cytotoxicity of ricin, modeccin, Pseudomonas toxin, and diphtheria toxin in brefeldin A-sensitive and -resistant cell lines.
Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis.
Effect of metal ions on diphtheria toxin production.
Effect of monophosphoryl lipid A on antibody response to diphtheria toxin and its subunits.
Effect of oligosaccharide chain length, exposed terminal group, and hapten loading on the antibody response of human adults and infants to vaccines consisting of Haemophilus influenzae type b capsular antigen unterminally coupled to the diphtheria protein CRM197.
Effect of Osteocyte-Ablation on Inorganic Phosphate Metabolism: Analysis of Bone-Kidney-Gut Axis.
Effect of oxidative stress on in vivo ADP-ribosylation of eukaryotic elongation factor 2.
Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration.
Effect of polymers of L-lysine on the cytotoxic action of diphtheria toxin.
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin.
Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment.
Effect of rate of intracellular transport and diacytosis on cytotoxicity of hybrid toxins. Study with hybrids using hepatic asialoglycoprotein receptor-mediated endocytosis.
Effect of site-directed mutagenic alterations on ADP-ribosyltransferase activity of the A subunit of Escherichia coli heat-labile enterotoxin.
Effect of skin barrier disruption on immune responses to topically applied cross-reacting material, CRM(197), of diphtheria toxin.
Effect of some substances on the mitochondrial swelling induced by diphtheria toxin in chicken embryo heart cell cultures.
Effect of the T-domain on intracellular transport of diphtheria toxin.
Effect of vaccination with carrier protein on response to meningococcal C conjugate vaccines and value of different immunoassays as predictors of protection.
Effect of vitamin A palmitate on mutagenesis induced by polycyclic aromatic hydrocarbons in human cells.
Effect on diphtheria immunity of combined tetanus and diphtheria booster vaccination in adults.
Effective targeted cytotoxicity of neuroblastoma cells.
Effective tumor targeting: strategies for the delivery of Armed Antibodies.
Effectiveness of anticancer drugs determined in nude mice inoculated with [125I]5-iodo-2'-deoxyuridine-prelabeled human melanoma cells.
Effector T Cells and Ischemia-Induced Systemic Angiogenesis in the Lung.
Effects of a chemically derived homo zwitterionic polysaccharide on immune activation in mice.
Effects of BCL-2 overexpression on the sensitivity of MCF-7 breast cancer cells to ricin, diphtheria and Pseudomonas toxin and immunotoxins.
Effects of cochlear hair cell ablation on spatial learning/memory.
Effects of CRM197, a specific inhibitor of HB-EGF, in oral cancer.
Effects of diphtheria toxin and other exotoxins on oxidant generation by human and murine phagocytes.
Effects of diphtheria toxin on acetylcholine synthesis.
Effects of dynamin inactivation on pathways of anthrax toxin uptake.
Effects of enhancer mutations on the expression of human immunodeficiency virus 1-regulated luciferase and diphtheria toxin A chain genes in transfected cells.
Effects of feeding probiotics during weaning on infections and antibody responses to diphtheria, tetanus and Hib vaccines.
EFFECTS OF HYPOPHYSECTOMY AND 2,2-BIS(CHLOROPHENYL)-1,1-DICHLOROETHANE ON THE ADRENAL CORTICAL RESPONSE TO DIPHTHERIA TOXIN.
Effects of lectins on the interaction of diphtheria toxin with mammalian cells.
Effects of local extraneural application of diphtheria toxin on the sciatic nerves of normal and protein deprived rats.
Effects of macrophage depletion on characteristics of cervix remodeling and pregnancy in CD11b-dtr mice.
Effects of mepanipyrim on intracellular trafficking: a comparative study on its effects on exocytic and endocytic trafficking of proteins, sphingolipids, and cholesterol.
Effects of mutations in proline 345 on insertion of diphtheria toxin into model membranes.
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis.
Effects of pseudomonas toxin A, diphtheria toxin, and cholera toxin on electrical characteristics of turtle bladder.
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin.
Effects of Vitamin C Intake upon the Degree of Tooth Injury Produced by Diphtheria Toxin.
Efferocytosis of apoptotic alveolar epithelial cells is sufficient to initiate lung fibrosis.
Efficacy of antiangiogenic targeted toxins against glioblastoma multiforme.
Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice.
Efficacy of Haemophilus influenzae type b vaccines in Massachusetts children 18 to 59 months of age.
Efficiency of cytoplasmic delivery by pH-sensitive liposomes to cells in culture.
Efficient B Cell Depletion via Diphtheria Toxin in CD19-Cre/iDTR Mice.
Efficient CRM197-mediated drug targeting to monocytes.
Efficient Delivery of Structurally Diverse Protein Cargo into Mammalian Cells by a Bacterial Toxin.
Efficient introduction of contents of liposomes into cells using HVJ (Sendai virus).
Efficient recovery of recombinant CRM197 expressed as inclusion bodies in E.coli.
Efrapeptins block exocytic but not endocytic trafficking of proteins.
EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins.
Electrical properties of isolated demyelinated rat nerve fibres.
Electrogene transfer of an Epstein-Barr virus-based plasmid replicon vector containing the diphtheria toxin A gene suppresses mammary carcinoma growth in SCID mice.
Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma.
Elimination of male germ cells in transgenic mice by the diphtheria toxin A chain gene directed by the histone H1t promoter.
Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding.
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin.
Elongation factor 2 as the major substrate for Ca2+/calmodulin-dependent protein kinase in rat adrenal glomerulosa cells.
Elongation factor 2 mutants deficient in diphthamide formation show temperature-sensitive cell growth.
Emergence of novel functions in striatal low-threshold spike interneurons.
Emergency myelopoiesis contributes to immune cell exhaustion and pulmonary vascular remodelling.
Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor.
Endogenous ADP-ribosylation for eukaryotic elongation factor 2: evidence of two different sites and reactions.
Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells.
Endogenous ADP-ribosylation of elongation factor-2 by interleukin-1?.
Endogenous ADP-ribosylation of eukaryotic elongation factor 2 and its 32 kDa tryptic fragment.
Endogenous foxp3(+) T-regulatory cells suppress anti-glomerular basement membrane nephritis.
Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice.
Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain.
Endosomal proteolysis of diphtheria toxin without toxin translocation into the cytosol of rat liver in vivo.
Endosome fusion induced by diphtheria toxin translocation domain.
Energetics of diphtheria toxin membrane insertion and translocation: calorimetric characterization of the acid pH induced transition.
Energy requirements for diphtheria toxin translocation are coupled to the maintenance of a plasma membrane potential and a proton gradient.
Engineered deafness reveals that mouse courtship vocalizations do not require auditory experience.
Engineered modular recombinant transporters: application of new platform for targeted radiotherapeutic agents to alpha-particle emitting 211 At.
Engineered toxins "zymoxins" are activated by the HCV NS3 protease by removal of an inhibitory protein domain.
Enhanced and long term immunogenicity of a Her-2/neu multi-epitope vaccine conjugated to the carrier CRM197 in conjunction with the adjuvant Montanide.
Enhanced antibody responses in infants given different sequences of heterogeneous Haemophilus influenzae type b conjugate vaccines.
Enhanced antitumor efficacy by combination treatment with a human umbilical vein endothelial cell vaccine and a tumor cell lysate-based vaccine.
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.
Enhanced inhibition of murine prostatic carcinoma growth by immunization with or administration of viable human umbilical vein endothelial cells and CRM197.
Enhanced interleukin-2 diphtheria toxin conjugate-induced growth suppression in retinoic acid-treated hypoxic hepatocellular carcinoma cells.
Enhanced internalization and endosomal escape of dual-functionalized poly(ethyleneimine)s polyplex with diphtheria toxin T and R domains.
Enhancement of cellular protein synthesis sensitivity to diphtheria toxin by interferon.
Enhancement of common mucosal immunity in aged mice following their supplementation with various antioxidants.
Enhancement of cytotoxicities of ricin and Pseudomonas toxin in Chinese hamster ovary cells by nigericin.
Enhancement of cytotoxicity of modeccin by nigericin in modeccin-resistant mutant cell lines.
Enhancement of diphtheria toxin activity by heat-killed bacteria and red blood-cells.
Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.
Enhancement of diphtheria toxin-induced apoptosis in Vero cells by combination treatment with brefeldin A and okadaic acid.
Enhancement of immunotoxin efficacy by acid-cleavable cross-linking agents utilizing diphtheria toxin and toxin mutants.
Enhancement of ricin cytotoxicity in Chinese hamster ovary cells by depletion of intracellular K+: evidence for an Na+/H+ exchange system in Chinese hamster ovary cells.
Enhancement of the cytotoxicity of mistletoe lectin-1 (ML-1) by high pH or perturbation in Golgi functions.
Enhancement of toxicity of saporin-based toxins by Gypsophila saponins--kinetic of the saponin.
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells.
Enrichment and efficient screening of ES cells containing a targeted mutation: the use of DT-A gene with the polyadenylation signal as a negative selection maker.
Enteric neuronal cell therapy reverses architectural changes in a novel diphtheria toxin-mediated model of colonic aganglionosis.
Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion.
Entry mechanisms of protein toxins and picornaviruses.
Entry of diphtheria toxin into cells: possible existence of cellular factor(s) for entry of diphtheria toxin into cells was studied in somatic cell hybrids and hybrid toxins.
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells.
Entry of diphtheria toxin-protein A chimeras into cells.
Entry of protein toxins in polarized epithelial cells.
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium.
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles.
Enzymatically active peptide from the adenosine diphosphate-ribosylating toxin of Pseudomonas aeruginosa.
Enzyme treatment of KB cells: the altered effect of diphtheria toxin.
Eosinophilic Granuloma with Splendore-Hoeppli Material Caused by Toxigenic Corynebacterium ulcerans in a Heifer.
Epidermal growth factor receptor-targeted cytotoxin inhibits neointimal hyperplasia in vivo. Results of local versus systemic administration.
Epidermal growth factor-toxin A chain conjugates: EGF-ricin A is a potent toxin while EGF-diphtheria fragment A is nontoxic.
Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity.
Epitope Mapping of the Diphtheria Toxin and Development of an ELISA-Specific Diagnostic Assay.
Epitope tagging of DAB389IL-2: new insights into C-domain delivery to the cytosol of target cells.
Epitopes for human CD4+ cells on diphtheria toxin: structural features of sequence segments forming epitopes recognized by most subjects.
Eradication of Haemophilus influenzae type b disease in southern California. Kaiser-UCLA Vaccine Study Group.
Essential lysine residues within transmembrane helix 1 of diphtheria toxin facilitate COPI binding and catalytic domain entry.
Estimate of myocardial damage induced by diphtheria toxin.
Estimating the direct impact of new conjugate vaccines against invasive pneumococcal disease.
Estimation of the time required for the process of diphtheria toxin formation.
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF.
Ethanol produces corticotropin-releasing factor receptor-dependent enhancement of spontaneous glutamatergic transmission in the mouse central amygdala.
Eukaryotic elongation factor 2 can bind to the synthetic oligoribonucleotide that mimics sarcin/ricin domain of rat 28S ribosomal RNA.
Eukaryotic elongation factor 2 loses its non-specific affinity for RNA and leaves polyribosomes as a result of ADP-ribosylation.
Eukaryotic expression vectors bearing genes encoding cytotoxic proteins for cancer gene therapy.
European sero-epidemiology network: standardisation of the results of diphtheria antitoxin assays.
Evaluation and characterisation of A and B fragments of Corynebacterium diphtheriae toxin towards recombinant diphtheria vaccine.
Evaluation of antidiphtheria toxin nanobodies.
Evaluation of cationic liposomes for delivery of diphtheria toxin A-chain gene to cells infected with bovine leukemia virus.
Evaluation of Critical Quality Attributes of a Pentavalent (A, C, Y, W, X) Meningococcal Conjugate Vaccine for Global Use.
Evaluation of human antibody responses to diphtheria toxin subunits A and B in various age groups.
Evaluation of single- and dual antigen delayed fluorescence immunoassay in comparison to an ELISA and the in vivo toxin neutralisation test for detection of diphtheria toxin antibodies.
Evaluation of synthetic schemes to prepare immunogenic conjugates of Vibrio cholerae O139 capsular polysaccharide with chicken serum albumin.
Evaluation of the Immunogenicity and Biological Activity of the Citrobacter freundii Vi-CRM197 Conjugate as a Vaccine for Salmonella enterica Serovar Typhi.
Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines.
Evaluation of the Serratia marcescens nuclease (NucA) as a transgenic cell ablation system in porcine.
Evidence for clathrin mobilization during directed phagocytosis of Shigella flexneri by HEp2 cells.
Evidence for direct insertion of fragments A and B of diphtheria toxin into model membranes.
Evidence for direct regulation of diphtheria toxin gene transcription by an Fe2+-dependent DNA-binding repressor, DtoxR, in Corynebacterium diphtheriae.
Evidence for involvement of furin in cleavage and activation of diphtheria toxin.
Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane.
Evidence of increased carriage of Corynebacterium spp. in healthy individuals with low antibody titres against diphtheria toxoid.
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments.
Evidence that divalent cations bind to diphtheria toxin: an ESR approach.
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells.
Evidence that the regulation of diphtheria toxin production is directed at the level of transcription.
Exacerbation of bacterial toxicity to infant ferrets by influenza virus: possible role in sudden infant death syndrome.
Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice.
Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Expanding MPEx Hydropathy Analysis to Account for Electrostatic Contributions to Protein Interactions with Anionic Membranes.
EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
Experimental diphtheritic neuropathy in the mouse: a study in cellular resistance.
Experimental study of diphtheritic polyneuritis in the rabbit and guinea pig. II. The effect of diphtheria toxin on lipide biosynthesis by guinea pig nerve.
Exploiting Bacterial Pathways for BBB Crossing with PLGA Nanoparticles Modified with a Mutated Form of Diphtheria Toxin (CRM197): In Vivo Experiments.
Exploiting the diphtheria toxin internalization receptor enhances delivery of proteins to lysosomes for enzyme replacement therapy.
Exploiting the Intron-splicing Mechanism of Insect Cells to Produce Viral Vectors Harboring Toxic Genes for Suicide Gene Therapy.
Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics.
Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice.
Exposure to low pH is not required for penetration of mosquito cells by Sindbis virus.
Expressing the diphtheria toxin A subunit from the HAP2(GCS1) promoter blocks sperm maturation and produces single sperm-like cells capable of fertilization.
Expression and assignment of the 1H, 15N, and 13C resonances of the C-terminal domain of the diphtheria toxin repressor.
Expression and characterization of recombinant soluble monkey CD3 molecules: mapping the FN18 polymorphic epitope.
Expression and characterization of recombinant soluble porcine CD3 ectodomain molecules: mapping the epitope of an anti-porcine CD3 monoclonal antibody 898H2-6-15.
Expression and distribution of CD9 in myelin of the central and peripheral nervous systems.
Expression and immunogenicity of a mutant diphtheria toxin molecule, CRM(197), and its fragments in Salmonella typhi vaccine strain CVD 908-htrA.
Expression and immunogenicity of a recombinant diphtheria toxin fragment A in Streptococcus gordonii.
Expression and purification of a trivalent pertussis toxin-diphtheria toxin-tetanus toxin fusion protein in Escherichia coli.
Expression and purification of the immunogenically active fragment B of the Park Williams 8 Corynebacterium diphtheriae strain toxin.
Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
Expression and purification of truncated diphtheria toxin, DT386, in
Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor.
Expression cloning of cDNAs that render cancer cells resistant to Pseudomonas and diphtheria toxin and immunotoxins.
Expression of a biologically active diphtheria toxin fragment B in Escherichia coli.
Expression of a mutant, full-length form of diphtheria toxin in Escherichia coli.
Expression of a poliovirus type 1 neutralization epitope on a diphtheria toxin fusion protein.
Expression of an anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin in a mutant CHO cell line.
Expression of bitter taste receptor Tas2r105 in mouse kidney.
Expression of diphtheria toxin A-chain in mature B-cells: a potential approach to therapy of B-lymphoid malignancy.
Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutants.
Expression of diphtheria toxin genes carried by integrated and nonintegrated phage beta.
Expression of diphtheria toxin in Streptococcus mutans and induction of toxin-neutralizing antisera.
Expression of DNA Coding for Diphtheria Toxin Chain A Is Toxic to Plant Cells.
Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain.
Expression of functional diphtheria toxin receptors on highly toxin-sensitive mouse cells that specifically bind radioiodinated toxin.
Expression of IL-13Ralpha2 in liver cancer cells and its effect on targeted therapy of liver cancer.
Expression of immunogenically reactive diphtheria toxin fusion proteins under the control of the pR promoter of bacteriophage lambda.
Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice.
Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice.
Expression of mutant dynamin protects cells against diphtheria toxin but not against ricin.
Expression of non-ADP-ribosylatable, diphtheria toxin-resistant elongation factor 2 in Saccharomyces cerevisiae.
Expression of the diphtheria toxin A-chain coding sequence under the control of promoters and enhancers from immunoglobulin genes as a means of directing toxicity to B-lymphoid cells.
Expression of the h19 oncofetal gene in premalignant lesions of cervical cancer: a potential targeting approach for development of nonsurgical treatment of high-risk lesions.
Expression of the virulence-related Sca (Mn2+) permease in Streptococcus gordonii is regulated by a diphtheria toxin metallorepressor-like protein ScaR.
Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage.
Extension of juxtamembrane domain of diphtheria toxin receptor arrests translocation of diphtheria toxin fragment A into cytosol.
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.
External quality assessment for the determination of diphtheria antitoxin in human serum.
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells.
Extracellular adenosine and slow-wave sleep are increased after ablation of nucleus accumbens core astrocytes and neurons in mice.
Extracellular Bad fused to toxin transport domains induces apoptosis.
Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C.
Extraneuronal saxitoxin binding sites in rabbit myelinated nerve.
Factors affecting ability of experimental vaccines to protect guinea pigs against lethal challenge with diphtheria toxin.
Failure of Diphtheria Toxin Model to Induce Parkinson-Like Behavior in Mice.
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol.
Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens.
Fat-Produced Adipsin Regulates Inflammatory Arthritis.
FCS study of the thermodynamics of membrane protein insertion into the lipid bilayer chaperoned by fluorinated surfactants.
Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner.
Fetal immune response following maternal diphtheria during early pregnancy.
Few Foxp3(+) regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.
Fibrinogen binds to nontoxigenic and toxigenic Corynebacterium diphtheriae strains.
Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells.
Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model.
Fifth vaccination with dipthteria, tetanus and acellular pertussis is beneficial in four- to six-year-olds.
Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains.
Flow cytometry analysis of synaptosomes from post-mortem human brain reveals changes specific to Lewy body and Alzheimer's disease.
Fluorescence characterization of the low pH-induced change in diphtheria toxin conformation: effect of salt.
Fluorescence studies of nucleotides binding to diphtheria toxin and its fragment A.
Folding changes in membrane-inserted diphtheria toxin that may play important roles in its translocation.
Folding funnels and conformational transitions via hinge-bending motions.
Folding of diphtheria toxin T-domain in the presence of amphipols and fluorinated surfactants: Toward thermodynamic measurements of membrane protein folding.
Following specific podocyte injury captopril protects against progressive long term renal damage.
Formation of a hybrid toxin from ricin agglutinin and a non-toxic mutant protein of diphtheria toxin.
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes.
Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche.
Foxp3 expression in macrophages associated with RENCA tumors in mice.
Foxp3(+) Regulatory T Cells Promote T Helper 17 Cell Development In Vivo through Regulation of Interleukin-2.
Foxp3+ Regulatory T Cell Depletion after Nonablative Oligofractionated Irradiation Boosts the Abscopal Effects in Murine Malignant Mesothelioma.
Foxp3+ regulatory T cells are required for recovery from severe sepsis.
Foxp3+ regulatory T cells control persistence of viral CNS infection.
Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.
Foxp3+ T Regulatory Cells as a Potential Target for Immunotherapy against Primary Infection with Echinococcus multilocularis Eggs.
Fractalkine Signaling Regulates Macrophage Recruitment into the Cochlea and Promotes the Survival of Spiral Ganglion Neurons after Selective Hair Cell Lesion.
Fragment A of diphtheria toxin causes pH-dependent lesions in model membranes.
Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
Fresh frozen plasma and platelet concentrates may increase plasma anti-diphtheria toxin IgG concentrations: implications for diphtheria fusion protein therapy.
From Laboratory to Clinic : The Story of CAM PA TH-1.
Function and transcriptomic dynamics of Sertoli cells during prospermatogonia development in mouse testis.
Function, structure and regulation of the vacuolar (H+)-ATPases.
Functional activity of maternal and cord antibodies elicited by an investigational group B Streptococcus trivalent glycoconjugate vaccine in pregnant women.
Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity.
Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins.
Functional comparison of the NAD binding cleft of ADP-ribosylating toxins.
Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type B polysaccharide-protein conjugates.
Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor.
Functional Redundancy of Langerhans Cells and Langerin(+) Dermal Dendritic Cells in Contact Hypersensitivity.
Functional studies of the Mycobacterium tuberculosis iron-dependent regulator.
Functional verification of the diphtheria toxin A gene in a recombinant system.
Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice.
Further observations on the production of diphtheria toxin in shake cultures by C. diphtheriae.
Further studies on Corynebacterium species capable of producing diphtheria toxin (C. diphtheriae, C. ulcerans, C. ovis).
Further Studies on the Immunizing Effect of Mixtures of Diphtheria Toxin and Antitoxin.
Further Studies upon the Effect of Various Carbohydrates on Production of Diphtheria Toxin with Special Reference to its Flocculating Titer and Final pH.
Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen.
Fusion between Jurkat cell and PEO-lipid modified liposome.
Fusion of diphtheria toxin and urotensin II produces a neurotoxin selective for cholinergic neurons in the rat mesopontine tegmentum.
Fusion protein toxins based on diphtheria toxin: selective targeting of growth factor receptors of eukaryotic cells.
Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells.
GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy.
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism.
Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner.
Gateways to clinical trials.
Gating of ion channels made by a diphtheria toxin fragment in phospholipid bilayer membranes.
Gene delivery with optimized electroporation parameters shows potential for treatment of gliomas.
Gene expression profile of human colon cancer cells treated with cross-reacting material 197, a diphtheria toxin non-toxic mutant.
Gene for the ADP-ribosylatable elongation factor 2 from the extreme thermoacidophilic archaebacterium Sulfolobus acidocaldarius. Cloning, sequencing, comparative analysis.
Gene for the diphtheria toxin-susceptible elongation factor 2 from Methanococcus vannielii.
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Gene therapy for human colorectal carcinoma using human CEA promoter contro led bacterial ADP-ribosylating toxin genes human CEA: PEA & DTA gene transfer.
Gene therapy of murine solid tumors with T cells transduced with a retroviral vascular endothelial growth factor--immunotoxin target gene.
Gene trap mutagenesis-based forward genetic approach reveals that the tumor suppressor OVCA1 is a component of the biosynthetic pathway of diphthamide on elongation factor 2.
Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice.
Generation and characterization of non-competitive furin-inhibiting nanobodies.
Generation of a Human Monoclonal Antibody to Cross-Reactive Material 197 (CRM???) and Development of a Sandwich ELISA for CRM??? Conjugate Vaccines.
Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells.
Generation of a novel mouse model for the inducible depletion of macrophages in vivo.
Generation of Human Renal Vesicles in Mouse Organ Niche Using Nephron Progenitor Cell Replacement System.
Generation of hybrid hybridomas secreting human IgM class hybrid antiricin and antidiphtheria toxin antibodies.
Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout.
Generation of plant-derived recombinant DTP subunit vaccine.
Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
Generation of Smad7(-Cre) recombinase mice: A useful tool for the study of epithelial-mesenchymal transformation within the embryonic heart.
Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene.
Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse.
Genetic Ablation of Floral Cells in Arabidopsis.
Genetic ablation of flowers in transgenic Arabidopsis.
Genetic Ablation of Mast Cells Redefines the Role of Mast Cells in Skin Wound Healing and Bleomycin-Induced Fibrosis.
Genetic ablation of petal and stamen primordia to elucidate cell interactions during floral development.
Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors.
Genetic ablation of root cap cells in Arabidopsis.
Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice.
Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diphtheria toxin in mouse-human somatic cell hybrids.
Genetic and biophysical studies of diphtheria toxin repressor (DtxR) and the hyperactive mutant DtxR(E175K) support a multistep model of activation.
Genetic assembly and selective toxicity of diphtheria-toxin-related polypeptide hormone fusion proteins.
Genetic construction and characterization of an anti-monkey CD3 single-chain immunotoxin with a truncated diphtheria toxin.
Genetic construction and characterization of the diphtheria toxin-related interleukin 15 fusion protein DAB389 sIL-15.
Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors.
Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein.
Genetic detoxification of bacterial toxins.
Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism.
Genetic fusion of three tandem copies of murine C3d sequences to diphtheria toxin fragment B elicits a decreased fragment B-specific antibody response.
Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system.
Genetic markers for quantitative mutagenesis studies in Chinese hamster ovary cells: characteristics of some recently developed selective systems.
Genetic platelet depletion is superior in platelet transfusion compared to current models.
Genetically designing a more potent antipancreatic cancer agent by simultaneously co-targeting human IL13 and EGF receptors in a mouse xenograft model.
Genetically engineered diphtheria toxin fusion proteins carrying the hepatitis B surface antigen.
Genetically engineering transferrin to improve its in vitro ability to deliver cytotoxins.
Genetics of cell surface receptors for bioactive polypeptides: variants of Swiss/3T3 fibroblasts resistant to a cytotoxic chimeric insulin.
Genetics of cell-surface receptors for bioactive polypeptides: a variant of mouse BALBc/3T3 fibroblasts possessing altered insulin-binding ability.
Genome-Wide Association Mapping of the Antibody Response to Diphtheria, Tetanus and Acellular Pertussis Vaccine in Mice.
Genomic epidemiology and strain taxonomy of Corynebacterium diphtheriae.
Glial remodeling enhances short-term memory performance in Wistar rats.
Global transcriptome analysis of T-competent progenitors in the bone marrow.
Global transcriptomic changes in glomerular endothelial cells in mice with podocyte depletion and glomerulosclerosis.
Glucose metabolism is altered after loss of L cells and ?-cells but not influenced by loss of K cells.
Glutamic acid 141 of the diphtheria toxin receptor (HB-EGF precursor) is critical for toxin binding and toxin sensitivity.
Glycoconjugate vaccines and immune interference: A review.
Glycoconjugate vaccines: some observations on carrier and production methods.
Glycoconjugation of Shigella flexneri type 2a O-polysaccharide with CRM197 as a potential vaccine candidate for shigellosis.
Glycoproteins of Sendai virus (HVJ) have a critical ratio for fusion between virus envelopes and cell membranes.
GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF.
GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials.
GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity.
Granulocyte-macrophage colony-stimulating factor induces expression of heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor and sensitivity to diphtheria toxin in human neutrophils.
Granulocyte-macrophage colony-stimulating factor receptor-targeted therapy of chemotherapy- and radiation-resistant human myeloid leukemias.
Growth inhibition of cancer cells by co-transfection of diphtheria toxin A-chain gene plasmid with bovine leukemia virus-tax expression vector.
Guinea pig line 10 hepatocarcinoma model: characterization of monoclonal antibody and in vivo effect of unconjugated antibody and antibody conjugated to diphtheria toxin A chain.
H19-promoter-targeted therapy combined with gemcitabine in the treatment of pancreatic cancer.
Haemophilus influenzae type b conjugate vaccines: a review of efficacy data.
Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin.
Half depletion of Foxp3+ regulatory T cells by diphtheria toxin for long-term study in vivo.
Hamster and rat fetal cells have low spontaneous mutation frequencies and rates.
Hamster diphtheria toxin receptor: a naturally occurring chimera of monkey and mouse HB-EGF precursors.
Haploid genetic screens in human cells identify host factors used by pathogens.
Heat shock proteins induce pores in membranes.
Heat-induced transcription of diphtheria toxin A or its variants, CRM176 and CRM197: implications for pancreatic cancer gene therapy.
HeLa cell mutants resistant to epidermal growth factor ricin A-chain conjugate.
Hematopoietic stem cells are not direct cytotoxic targets of natural killer cells.
HEMORRHAGES IN SKIN LESIONS OF GUINEA PIGS FOLLOWING INTRAVASCULAR INJECTION OF TOXINS (SHWARTZMAN PHENOMENON).
HEMORRHAGES IN TUBERCULOUS GUINEA PIGS AT THE SITE OF INJECTION OF IRRITANTS FOLLOWING INTRAVASCULAR INJECTIONS OF INJURIOUS SUBSTANCES (SHWARTZMAN PHENOMENON).
Heparin-binding EGF-like growth factor in the human prostate: synthesis predominantly by interstitial and vascular smooth muscle cells and action as a carcinoma cell mitogen.
Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder.
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity.
Heparin-binding EGF-like growth factor.
Heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor expression by acute myeloid leukemia cells.
Heparin-like molecules on the cell surface potentiate binding of diphtheria toxin to the diphtheria toxin receptor/membrane-anchored heparin-binding epidermal growth factor-like growth factor.
Hepatitis E vaccine candidate harboring a non-particulate immunogen of E2 fused with CRM197 fragment A.
Heterogeneity of diphtheria toxin gene, tox, and its regulatory element, dtxR, in Corynebacterium diphtheriae strains causing epidemic diphtheria in Russia and Ukraine.
Heterogeneity of native rat liver elongation factor 2.
High affinity interleukin-3 receptor expression on blasts from patients with acute myelogenous leukemia correlates with cytotoxicity of a diphtheria toxin/IL-3 fusion protein.
High level accumulation of soluble diphtheria toxin mutant (CRM197) with co-expression of chaperones in recombinant Escherichia coli.
High-level Expression and Characterization of the Fusion Protein Consisting of Diphtheria Toxin and Human Interleukin 6.
High-level expression and purification of the recombinant diphtheria fusion toxin DTGM for PHASE I clinical trials.
High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli.
High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.
High-yield production of diphtheria toxin mutants by high-density culture of C7 (beta)tox+ strains grown in a non-deferrated medium.
High-yield production of recombinant CRM197, a non-toxic mutant of diphtheria toxin, in the periplasm of Escherichia coli.
Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene.
Highly frequent single amino acid substitution in mammalian elongation factor 2 (EF-2) results in expression of resistance to EF-2-ADP-ribosylating toxins.
Highly purified mutant E112K of cholera toxin elicits protective lung mucosal immunity to diphtheria toxin.
Hilar mossy cell degeneration causes transient dentate granule cell hyperexcitability and impaired pattern separation.
Histidine 21 does not play a major role in diphtheria toxin catalysis.
Histidine 21 is at the NAD+ binding site of diphtheria toxin.
Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer.
Histidine-21 is involved in diphtheria toxin NAD+ binding.
Histochemical alterations in succinic dehydrogenase activity of guinea pig tissues following administration of diphtheria toxin.
Histochemical study of neuronal necrosis produced by intracerebral injection of diphtheria toxin.
Histological analysis of CD11c-DTR/GFP mice after in vivo depletion of dendritic cells.
Histological examination on osteoblastic activities in the alveolar bone of transgenic mice with induced ablation of osteocytes.
Histological, histochemical and electron microscopic studies on effects of diphtheria toxin on the adrenals of guinea pigs.
Hitting the bullseye with a nonlethal payload: resistance in CD123-positive malignancies.
HIV-1 Membrane-Proximal External Region Fused to Diphtheria Toxin Domain-A Elicits 4E10-Like Antibodies in Mice.
HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses.
HIV-regulated diphtheria toxin A chain gene confers long-term protection against HIV type 1 infection in the human promonocytic cell line U937.
HMGB1 aggravates lipopolysaccharide-induced acute lung injury through suppressing the activity and function of Tregs.
HN glycoprotein of HVJ (Sendai virus) enhances the selective cytotoxicity of diphtheria toxin fragment A-containing liposomes on subacute sclerosing panencephalitis virus-infected cells.
Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice.
Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.
Homologous Recombination in Zebrafish ES Cells.
Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.
How bacterial protein toxins enter cells; the role of partial unfolding in membrane translocation.
How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
How might demyelinating disorders and glaucoma modify synaptic function?
How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets.
Human alpha-defensins inhibit hemolysis mediated by cholesterol-dependent cytolysins.
Human antibodies neutralizing diphtheria toxin in vitro and in vivo.
Human antibody response to fragments A and B of diphtheria toxin and a synthetic peptide of amino acid residues 141-157 of fragment A.
Human antibody responses to two conjugate vaccines of Haemophilus influenzae type B saccharides and diphtheria toxin.
Human clinical isolates of Corynebacterium diphtheriae and Corynebacterium ulcerans collected in Canada from 1999 to 2003 but not fitting reporting criteria for cases of diphtheria.
Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes.
Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities.
Human immunodeficiency virus-1 tat- and tat/nef-defective genomes containing HIV-regulated diphtheria toxin A chain gene inhibit HIV replication.
Human liver chimeric mouse model based on diphtheria toxin-induced liver injury.
Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model.
Human neural stem cell differentiation following transplantation into spinal cord injured mice: association with recovery of locomotor function.
Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice.
Human pancreatic adenocarcinoma line Capan-1 in tissue culture and the nude mouse: morphologic, biologic, and biochemical characteristics.
Human Skin-Tolerance to Diphtheria Toxin, and Immunizability.
Humanized immunotoxins: a new generation of immunotoxins for targeted cancer therapy.
Humoral and cell mediated immune responses to a pertussis containing vaccine in pregnant and nonpregnant women.
Hybrid tetanus toxin C fragment-diphtheria toxin translocation domain allows specific gene transfer into PC12 cells.
Hybrid toxin of the A chain of ricin toxin and a subunit of Wistaria floribunda lectin. Possible importance of the hydrophobic region for entry of toxin into the cell.
Hydrogen-deuterium exchange and mass spectrometry reveal the pH-dependent conformational changes of diphtheria toxin T domain.
Hydrogen-Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin.
Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase.
Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen.
Hypoganglionosis in the gastric antrum causes delayed gastric emptying.
Hypothalamic preprosomatostatin messenger ribonucleic acid expression in mice transgenic for excess or deficient endogenous growth hormone.
Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.
Identification and characterization of cell lines with a defect in a post-adsorption stage of Sendai virus-mediated membrane fusion.
Identification and characterization of small molecules that inhibit intracellular toxin transport.
Identification and characterization of three new promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron.
Identification and isolation of kidney-derived stem cells from transgenic rats with diphtheria toxin-induced kidney damage.
Identification of a diphtheria toxin-like gene family beyond the Corynebacterium genus.
Identification of a DtxR-regulated operon that is essential for siderophore-dependent iron uptake in Corynebacterium diphtheriae.
Identification of a Guinea Pig Fc? Receptor that Exhibits Enhanced Binding to Afucosylated Human and Mouse IgG.
Identification of a Human Monoclonal Antibody to Replace Equine Diphtheria Anti-toxin for the Treatment of Diphtheria Intoxication.
Identification of a novel population of Langerin+ dendritic cells.
Identification of a single amino acid substitution in the diphtheria toxin A chain of CRM 228 responsible for the loss of enzymatic activity.
Identification of a two-component signal transduction system from Corynebacterium diphtheriae that activates gene expression in response to the presence of heme and hemoglobin.
Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.
Identification of Conformational B-cell Epitopes in Diphtheria Toxin at Varying Temperatures Using Molecular Dynamics Simulations.
Identification of Deoxyribonucleic Acid Restriction Fragments of ?-Converting Corynebacteriophages That Carry the Gene for Diphtheria Toxin.
Identification of deoxyribonucleic acid restriction fragments of beta-converting corynebacteriophages that carry the gene for diphtheria toxin.
Identification of diphtheria toxin R domain mutants with enhanced inhibitory activity against HB-EGF.
Identification of diphtheria toxin receptor and a nonproteinous diphtheria toxin-binding molecule in Vero cell membrane.
Identification of diphtheria toxin via screening as a potent cell cycle and p53-independent cytotoxin for human prostate cancer therapeutics.
Identification of Formaldehyde-Induced Modifications in Diphtheria Toxin.
Identification of functional epitopes of Pseudomonas aeruginosa exotoxin A using synthetic peptides and subclone products.
Identification of host cell factors required for intoxication through use of modified cholera toxin.
Identification of Nsp100 as elongation factor 2 (EF-2).
Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activity.
Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width.
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.
Identification of the gene encoding the mitochondrial elongation factor G in mammals.
Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.
Identification of the primary metal ion-activation sites of the diphtheria tox repressor by X-ray crystallography and site-directed mutational analysis.
Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.
Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain.
IgG subclass distribution of antibodies after vaccination of adults with pneumococcal conjugate vaccines.
IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells.
IgG1, IgG2 and IgM responses to two Haemophilus influenzae type b conjugate vaccines in young infants.
IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity.
IL-23 from Langerhans Cells Is Required for the Development of Imiquimod-Induced Psoriasis-Like Dermatitis by Induction of IL-17A-Producing ?? T Cells.
IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury.
Ilimaquinone inhibits the cytotoxicities of ricin, diphtheria toxin, and other protein toxins in Vero cells.
Immature doublecortin-positive hippocampal neurons are important for learning but not for remembering.
Immobilization of reticulocyte elongation factor EF-2.
Immune activation and virologic response to immunization in recent HIV type 1 seroconverters.
Immune and allergic reactions to diphtheria toxin and toxoid in guinea-pigs.
Immune response to diphtheria toxin and to different CNBr fragments: evidence for different B and T cell reactivities.
Immune status against diphtheria toxin in tea garden population surveyed in Dibrugarh district, Assam.
Immune-Mediated Specific Depletion of Intestinal Stem Cells.
Immunity of Guinea-pigs to Diphtheria Toxin and its Effect upon the Offspring.
Immunity of Guinea-pigs to Diphtheria Toxin and its Effect upon the Offspring: Part 1.
Immunity of Guinea-pigs to Diphtheria Toxin and its Effect upon the Offspring: Part 2.
Immunity to diphtheria in northern Norway and northwestern Russia.
Immunization of 2-month-old infants with protein-coupled oligosaccharides derived from the capsule of Haemophilus influenzae type b.
Immunization with the conjugate vaccine Vi-CRM(197) against Salmonella Typhi induces Vi-specific mucosal and systemic immune responses in mice.
Immunochemical analysis of the N-acetyl hexosaminidases in human-mouse hybrids made using a double selective system.
Immunochemical analysis of the structure of diphtheria toxin shows all three domains undergo structural changes at low pH.
Immunochemical analysis shows all three domains of diphtheria toxin penetrate across model membranes.
Immunochromatographic strip test for rapid detection of diphtheria toxin: description and multicenter evaluation in areas of low and high prevalence of diphtheria.
Immunodeficiency in alpha-mannosidosis: a matched case-control study on immunoglobulins, complement factors, receptor density, phagocytosis and intracellular killing in leucocytes.
Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak(®) on CD25(+) cells.
Immunogenic correlation between cross-reacting material (CRM197) produced by a mutant of Corynebacterium diphtheriae and diphtheria toxoid.
Immunogenicity and efficacy of a rationally designed vaccine against vascular endothelial growth factor in mouse solid tumor models.
Immunogenicity and reactogenicity of a single dose of a diphtheria--tetanus--acellular pertussis component vaccine (DTaP) compared to a diphtheria--tetanus toxoid (Td) and a diphtheria toxoid vaccine (d) in adults.
Immunogenicity and reactogenicity of diphtheria, tetanus and pertussis toxoids combined with inactivated polio vaccine, when administered concomitantly with or as a diluent for a Hib conjugate vaccine.
Immunogenicity and reactogenicity of HbOC vaccine administered simultaneously with acellular pertussis vaccine (DTaP) into either arms or thighs of infants.
Immunogenicity and safety of a fully liquid aluminum phosphate adjuvanted Haemophilus influenzae type b PRP-CRM197-conjugate vaccine in healthy Japanese children: A phase III, randomized, observer-blind, multicenter, parallel-group study.
Immunogenicity of anti-Haemophilus influenzae type b CRM197 conjugate following mucosal vaccination with oligodeoxynucleotide containing immunostimulatory sequences as adjuvant.
Immunogenicity of genetically engineered glutathione S-transferase fusion proteins containing a T-cell epitope from diphtheria toxin.
Immunogenicity of Haemophilus influenzae oligosaccharide-protein and polysaccharide-protein conjugate vaccination of children at 4, 6, and 14 months of age.
Immunogenicity of Haemophilus influenzae type b conjugate vaccines in infant rhesus monkeys.
Immunogenicity of Haemophilus influenzae type b conjugate vaccines in Korean infants: a meta-analysis.
Immunogenicity of IRIV- versus alum-adjuvanted diphtheria and tetanus toxoid vaccines in influenza primed mice.
Immunogens consisting of oligosaccharides from the capsule of Haemophilus influenzae type b coupled to diphtheria toxoid or the toxin protein CRM197.
Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway.
Immunological characterization of diphtheria toxin recovered from Corynebacterium pseudotuberculosis.
Immunological cross-reactivity in the absence of DNA homology between Pseudomonas toxin A and diphtheria toxin.
Immunomodulatory role of non-neuronal cholinergic signaling in myocardial injury.
Immunoprecipitation and partial characterization of diphtheria toxin-binding glycoproteins from surface of guinea pig cells.
Immunosuppressive effects of streptozotocin-induced diabetes result in absolute lymphopenia and a relative increase of T regulatory cells.
Immunotherapy of experimental animal tumors with antitumor antibodies conjugated to diphtheria toxin or ricin.
Immunotherapy using interleukin-2 diphtheria toxin chimer prolongs murine allografts.
Immunotoxin FN18-CRM9 induces stronger T cell signaling than unconjugated monoclonal antibody FN18.
Immunotoxin pharmacokinetics: a comparison of the anti-glioblastoma bi-specific fusion protein (DTAT13) to DTAT and DTIL13.
Immunotoxins for targeted cancer therapy.
Immunotoxins in cancer therapy: Review and update.
Immunotoxins in the treatment of hematologic malignancies.
Immunotoxins show rapid entry of diphtheria toxin but not ricin via the T3 antigen.
Immunotoxins.
Immunotoxins: is there a clinical value?
Impact of interleukin-2-receptor-targeted cytotoxins on a unique model of murine interleukin-2-receptor-expressing malignancy.
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Impairment of podocyte function by diphtheria toxin--a new reversible proteinuria model in mice.
Implicating Exudate Macrophages and Ly-6Chigh Monocytes in CCR2-Dependent Lung Fibrosis following Gene-Targeted Alveolar Injury.
Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast.
Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity.
Improved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion.
Improved specificity of a multiplex immunoassay for quantitation of anti-diphtheria toxin antibodies with the use of diphtheria toxoid.
Improvement of a recombinant anti-monkey anti-CD3 diphtheria toxin based immunotoxin by yeast display affinity maturation of the scFv.
Improvement of the survival rate by fetal liver cell transplantation in a mice lethal liver failure model.
In mice lacking V2a interneurons, gait depends on speed of locomotion.
In Reply: Does Diphtheria Toxin Have Nuclease Activity?
In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs).
In silico design of fusion toxin DT389GCSF and comparison of interaction it with GCSF receptor rather than DT486GCSF.
In vitro assays for detection of diphtheria toxin.
In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin.
In vitro determination of antigen quality: biosensor analysis and fluorescence spectroscopy.
In vitro efficacy of recombinant diphtheria toxin-murine interleukin-4 immunoconjugate on mouse glioblastoma and neuroblastoma cell lines and the additive effect of radiation.
In vitro efficacy of transferrin-toxin conjugates against glioblastoma multiforme.
In vitro expression of the diphtheria toxin A-chain gene under the control of human chorionic gonadotropin gene promoters as a means of directing toxicity to ovarian cancer cell lines.
In vitro induction of a Haemophilus influenzae type b polysaccharide-specific antibody response in human peripheral blood lymphocytes of individuals recently vaccinated with an oligosaccharide-protein conjugate.
In vitro inhibition of diphtheria toxin action by ammonium salts and amines.
In vitro interaction of eukaryotic elongation factor 2 with synthetic oligoribonucleotide that mimics GTPase domain of rat 28S ribosomal RNA.
In vitro interleukin-3 binding to leukemia cells predicts cytotoxicity of a diphtheria toxin/IL-3 fusion protein.
In vitro studies on the comparative sensitivities of cells of the central nervous system to diphtheria toxin.
In vitro-translated diphtheria toxin A chain inhibits translation in wheat germ extracts: analysis of biologically active, caspase-3-resistant diphtheria toxin mutants.
In Vivo Ablation of a Dendritic Cell Subset Expressing the Chemokine Receptor XCR1.
In vivo administration of plasmid DNA encoding recombinant immunotoxin DT390-IP-10 attenuates experimental autoimmune encephalomyelitis.
In vivo antitumor effect of cationic liposomes containing diphtheria toxin A-chain gene on cells infected with bovine leukemia virus.
In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor.
In vivo dendritic cell depletion reduces breeding efficiency, affecting implantation and early placental development in mice.
In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.
In vivo depletion of FoxP3+ Tregs using the DEREG mouse model.
In vivo effect of prednisolone on diphtheria toxin.
In Vivo Expansion of Regulatory T cells with IL-2/IL-2 Antibody Complex Protects against Transient Ischemic Stroke.
In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A.
In vivo induction of T-follicular helper cells by modulation of regulatory T cell function.
In vivo proliferative regeneration of balance hair cells in newborn mice.
In vivo regeneration of interspecies chimeric kidneys using a nephron progenitor cell replacement system.
In vivo reprogramming of UV radiation-induced regulatory T-cell migration to inhibit the elicitation of contact hypersensitivity.
In Vivo Rescue of the Hematopoietic Niche By Pluripotent Stem Cell Complementation of Defective Osteoblast Compartments.
In vivo T cell depletion in miniature swine using the swine CD3 immunotoxin, pCD3-CRM9.
In vivo T-cell ablation by a holo-immunotoxin directed at human CD3.
In vivo targeting of leukemic cells using diphtheria toxin fused to murine GM-CSF.
In Vivo Tumor Therapy with Novel Immunotoxin Containing Programmed Cell Death Protein-1 and Diphtheria Toxin.
Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma.
Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells.
Inactivation of aminoacyl transferase II by diphtheria toxin.
Increase in detection of Corynebacterium diphtheriae in Canada: 2006-2019.
Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein.
Increased cytotoxicity of ricin in a putative Golgi-defective mutant of Chinese hamster ovary cell.
Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells.
Increased latencies to initiate cocaine self-administration following laterodorsal tegmental nucleus lesions.
Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing.
Increased toxicity of diphtheria toxin for human lymphoblastoid cells following covalent linkage to anti-(human lymphocyte) globulin or its F(ab')2 fragment.
Increased transgene expression by the mouse tyrosinase enhancer is restricted to neural crest-derived pigment cells.
Increased tubular proliferation as an adaptive response to glomerular albuminuria.
Increasing Cancer-Specific Gene Expression by Targeting Overexpressed ?5?1 Integrin and Upregulated Transcriptional Activity of NF-?B.
Induced ablation of ghrelin cells in adult mice does not decrease food intake, body weight, or response to high-fat diet.
Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells.
Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis.
Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses.
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity.
Inducible reporter/driver lines for the Arabidopsis root with intrinsic reporting of activity state.
Inducible targeting of cDCs and their subsets in vivo.
Induction and Resuscitation of Viable but Nonculturable Corynebacterium diphtheriae.
Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin.
Induction of diphtheria toxin-resistant cells by mutagen-carcinogens.
Induction of diphtheria toxin-resistant mutants in human cells by halogenated compounds.
Induction of diphtheria toxin-resistant mutants in human cells by ultraviolet light.
Induction of immunologic memory in infants primed with Haemophilus influenzae type b conjugate vaccines.
Induction of male sterile cabbage using a tapetum-specific promoter from Brassica campestris L. ssp. pekinensis.
Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.
Induction of ornithine decarboxylase activity in a temperature-sensitive cell cycle mutant of Chinese hamster cells.
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor.
Infant antibody levels following 10-valent pneumococcal-protein D conjugate and DTaP-Hib vaccinations in the first year of life after maternal Tdap vaccination: An open-label, parallel, randomised controlled trial.
Infection due to "Corynebacterium ulcerans", producing diphtheria toxin--a case report from Denmark.
Infection of the skin caused by Corynebacterium ulcerans and mimicking classical cutaneous diphtheria.
Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice.
Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis.
Influence of anti-fragment A of diphtheria toxin on passive hemagglutination with antitoxin.
Influence of diphtheria toxin on free fatty acid mobilization and pressor responses to catecholamines.
INFLUENCE OF DIPHTHERIA TOXIN ON THE PHOSPHORYLATION OF THIAMINE.
Influence of levamisole on the immune response of old people.
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
Influence of protein transduction domains on target-specific chimeric proteins.
Influenza virus enhancement of membrane leakiness induced by staphylococcal alpha toxin, diphtheria toxin and streptolysin S.
Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase.
Inhibition of adrenocortical carcinoma by diphtheria toxin mutant CRM197.
Inhibition of AIDS-associated Kaposi's sarcoma cell growth by DAB389-interleukin 6.
Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds.
Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin.
Inhibition of diphtheria toxin degradation and cytotoxic action by chloroquine.
Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin, Pseudomonas aeruginosa exotoxin A, and ricin.
Inhibition of growth of Erlich tumors in Swiss mice by diphtheria toxin.
Inhibition of HIV production in cells containing an integrated, HIV-regulated diphtheria toxin A chain gene.
Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction.
Inhibition of human immunodeficiency virus type 1 by Tat/Rev-regulated expression of cytosine deaminase, interferon alpha2, or diphtheria toxin compared with inhibition by transdominant Rev.
Inhibition of human immunodeficiency virus-1 production resulting from transduction with a retrovirus containing an HIV-regulated diphtheria toxin A chain gene.
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges.
Inhibition of metabolic cooperation by phorbol esters in a cell culture system based on adenosine kinase deficient mutants of V79 cells.
Inhibition of mitochondrial protein synthesis and energy coupling by fragment A of diphtheria toxin.
Inhibition of mouse spleen cell function by diphtheria toxin fragment A coupled to anti-mouse Thy-1.2 and by ricin A chain coupled to anti-mouse IgM.
Inhibition of neovascularisation in human endothelial cells using anti NRP-1 nanobody fused to truncated form of diphtheria toxin as a novel immunotoxin.
Inhibition of ovulation in hamsters by the protein synthesis inhibitors diphtheria toxin and cycloheximide.
Inhibition of p21 Rho in intact cells by C3 diphtheria toxin chimera proteins.
Inhibition of peptide chain elongation in a cell-free system from yeast by pre-incubation of the yeast peptidyl-translocase with diphtheria toxin and NAD.
Inhibition of protein synthesis after intravenous or intramuscular challenge with diphtheria toxin.
Inhibition of protein synthesis by diphtheria toxin induces a peculiar pattern of synthesized protein species.
Inhibition of protein synthesis elicits early grey crescent formation in the axolotl oocyte.
Inhibition of protein synthesis in small cell lung cancer cells induced by the diphtheria toxin-related fusion protein DAB389 GRP.
Inhibition of the cytotoxicity of protein toxins by a novel plant metabolite, mansonone-D.
Inhibition of transferrin iron release increases in vitro drug carrier efficacy.
Inhibition of tumor growth by DT-A expressed under the control of IGF2 P3 and P4 promoter sequences.
Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states.
Inhibitors of polypeptide elongation on yeast polysomes.
Inhibitory effect of dideoxyforskolin on cell death induced by ricin, modeccin, diphtheria toxin, and Pseudomonas toxin in MDCK cells.
Inhibitory effect of diphtheria toxin on amino acid incorporation in Escherichia coli cell-free system.
Innate versus learned odour processing in the mouse olfactory bulb.
Inositol 1,4,5-trisphosphate directly opens diphtheria toxin channels.
Insertion of a targeting peptide on capsid surface loops of human papillomavirus type-16 virus-like particles mediate elimination of anti-dsDNA Abs-producing B cells with high efficiency.
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions.
Insertion of diphtheria toxin in lipid bilayers studied by spin label ESR.
Insertion of diphtheria toxin into and across membranes: role of phosphoinositide asymmetry.
Insights into diphthamide, key diphtheria toxin effector.
Insights on FoxN1 biological significance and usages of the "nude" mouse in studies of T-lymphopoiesis.
Insights to the diphtheria toxin encoding prophages amongst clinical isolates of Corynebacterium diphtheriae from India.
Insights to the Diphtheria Toxin Encoding Prophages amongst Clinical Isolates of Corynebacterium diphtheriae from India.
Integration of corynebacteriophages beta tox+, omega tox+, and gamma tox- into two attachment sites on the Corynebacterium diphtheriae chromosome.
Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts.
Interaction of aminoacyl transferase II and guanosine triphosphate: inhibition by diphtheria toxin and nicotinamide adenine dinucleotide.
Interaction of an alpha-melanocyte-stimulating hormone-diphtheria toxin fusion protein with melanotropin receptors in human melanoma metastases.
Interaction of cultured mammalian cells with [125I] diphtheria toxin.
Interaction of diphtheria toxin (fragment A) with actin.
Interaction of diphtheria toxin and its active subunit, fragment A, with toxin-sensitive and toxin-resistant cells.
Interaction of diphtheria toxin fragment A and of elongation factor 2 with cibacron blue.
Interaction of diphtheria toxin fragments A, B and protein crm 45 with liposomes.
Interaction of diphtheria toxin T domain with molten globule-like proteins and its implications for translocation.
Interaction of diphtheria toxin with adenylyl-(3',5')-uridine 3'-monophosphate. I. Equilibrium and kinetic measurements.
Interaction of diphtheria toxin with adenylyl-(3',5')-uridine 3'-monophosphate. II. The NAD-binding site and determinants of dinucleotide affinity.
Interaction of diphtheria toxin with cell cultures from susceptibile and resistant animals.
Interaction of diphtheria toxin with mammalian cell membranes.
Interaction of diphtheria toxin with model membranes.
Interaction of diphtheria toxin with phosphorylated molecules.
Interaction of elongation factor 2 from wheat germ with guanosine nucleotides and ribosomes.
Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide.
INTERACTION OF MITOCHONDRIAL STRUCTURAL PROTEIN WITH DIPHTHERIA TOXIN.
Interaction of pertussis toxin with cells and model membranes.
Interaction of the isolated transmembrane domain of diphtheria toxin with membranes.
Interaction of the membrane-inserted diphtheria toxin T domain with peptides and its possible implications for chaperone-like T domain behavior.
Interaction of toxin of Corynebacterium diphtheriae with phagocytes from susceptible and resistant species.
Interaction of transferrin, haptoglobin and other serum proteins with neuraminidase of diphtheria toxin.
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells.
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin.
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate.
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport.
Interactions of conjugate vaccines and co-administered vaccines.
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions.
Interactions of diphtheria toxin with lipid vesicles: determinants of ion channel formation.
Interactions of fluorinated surfactants with diphtheria toxin T-domain: testing new media for studies of membrane proteins.
Interactions of liposome bilayers composed of 1,2-diacyl-3-succinylglycerol with protons and divalent cations.
Interfacial folding and membrane insertion of a designed helical peptide.
Interleukin 1 beta and Matrix Metallopeptidase 3 Contribute to Development of EGFR-dependent Serrated Polyps in Mouse Cecum.
Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
Interleukin 2 toxin: a step toward selective immunomodulation.
Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.
Interleukin 4 receptor targeted cytotoxicity: genetic construction and in vivo immunosuppressive activity of a diphtheria toxin-related murine interleukin 4 fusion protein.
Interleukin 7 (IL-7) receptor-specific cell killing by DAB389 IL-7: a novel agent for the elimination of IL-7 receptor positive cells.
Interleukin-2 fusion protein (DAB389IL-2) selectively targets activated human peripheral blood and lamina propria lymphocytes.
Interleukin-2 fusion protein: an investigational therapy for interleukin-2 receptor expressing malignancies.
Interleukin-2 fusion toxin: targeted therapy for cutaneous T cell lymphoma.
Interleukin-2-diphtheria toxin fusion protein prolongs murine islet cell engraftment.
Interleukin-4 receptor expression by human B cells: functional analysis with a human interleukin-4 toxin, DAB389IL-4.
Intermediates in translocation of diphtheria toxin across the plasma membrane.
Internalization of CD239 highly expressed in breast cancer cells: a potential antigen for antibody-drug conjugates.
Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition.
Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.
Intoxication of cells from different-aged embryos by diphtheria toxin.
Intoxication of normal and virus-transformed cells by diphtheria toxin.
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.
Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells.
Intracellular expression of toxic shock syndrome toxin 1 in Saccharomyces cerevisiae.
Intracellular localization and degradation of diphtheria toxin.
Intracellular Mono-ADP-Ribosylation in Signaling and Disease.
Intracellular stability of diphtheria toxin fragment A in the presence and absence of anti-fragment A antibody.
Intracellular targeting with low pH-triggered bispecific antibodies.
Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway.
Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer.
Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery.
Intracranial therapy of glioblastoma with the fusion protein DTAT in immunodeficient mice.
Intracranial therapy of glioblastoma with the fusion protein DTIL13 in immunodeficient mice.
Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan.
Intraneural injection of diphtheria toxin.
Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth.
Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery.
Intravenously Transplanted Human Multilineage-Differentiating Stress-Enduring Cells Afford Brain Repair in a Mouse Lacunar Stroke Model.
Introduction of additional charges as an aid in protein purification: isolation of elongation factor 2 from Sulfolobus acidocaldarius by preparative isoelectric focusing before and after ADP-ribosylation.
Introduction of macromolecules into hemopoietic stem cells with an erythrocyte-ghost-mediated system.
Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogs and 32P-NAD.
Investigating the function of follicular subpopulations during Drosophila oogenesis through hormone-dependent enhancer-targeted cell ablation.
Investigation into the catalytic role for the tryptophan residues within domain III of Pseudomonas aeruginosa exotoxin A.
Investigation of bi-potent differentiation of hepatoblasts using inducible diphtheria toxin receptor-transgenic mice.
Investigation of the action of poly(ADP-ribose)-synthesising enzymes on NAD(+) analogues.
Investigations into the relationship between structure and function of diphtheria toxin.
Investigations of 2 cases of diphtheria-like illness due to toxigenic Corynebacterium ulcerans.
Involvement of both caspase-like proteases and serine proteases in apoptotic cell death induced by ricin, modeccin, diphtheria toxin, and pseudomonas toxin.
Involvement of Dendritic Cells and Th17 Cells in Induced Tertiary Lymphoid Structures in a Chronic Beryllium Disease Mouse Model.
Ion channel and membrane translocation of diphtheria toxin.
Iron and diphtheria toxin production.
Iron regulation of the cloned diphtheria toxin promoter in Escherichia coli.
Iron, DtxR, and the regulation of diphtheria toxin expression.
Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C. diphtheriae C7 strains.
Is sporadic Alzheimer's disease associated with diphtheria toxin?
Islet pericytes are required for beta-cell maturity.
Isoelectric focusing of human anti-diphtheria toxoid antibodies: identical spectrotypes of anti-fragment A antibodies with the same IgG subclass and light chain constant regions are expressed in multiple individuals.
Isolation and characterization of a flowering plant male gametic cell-specific promoter.
Isolation and characterization of Corynebacterium diphtheriae nontandem double lysogens hyperproducing CRM197.
Isolation and characterization of Corynebacterium ulcerans from cephalic implants in macaques.
Isolation and characterization of eft-1, an elongation factor 2-like gene on chromosome III of Caenorhabditis elegans.
Isolation and characterization of iron-independent positive dominant mutants of the diphtheria toxin repressor DtxR.
Isolation and characterization of mutants of human diploid fibroblasts resistant to diphtheria toxin.
Isolation and characterization of the cyanogen bromide peptides from the B fragment of diphtheria toxin.
Isolation and characterization of tox mutants of corynebacteriophage beta.
Isolation and characterization of toxigenic Corynebacterium ulcerans from 2 closed colonies of cynomolgus macaques (Macaca fascicularis) in Japan.
Isolation and distribution of elongation factor 2 in eggs and embryos of sea urchins.
Isolation and partial characterization of a corynebacteriophage beta, tox operator constitutive-like mutant lysogen of Corynebacterium diphtheriae.
Isolation and properties of the trypsin-derived ADP-ribosyl peptide from diphtheria toxin-modified yeast elongation factor 2.
Isolation of a human monoclonal antibody with strong neutralizing activity against diphtheria toxin.
Isolation of diphtheria toxin-sensitive mouse cells from a toxin-resistant population transfected with monkey DNA.
Isolation of human monoclonal antibodies binding to B fragment of diphtheria toxin.
Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity.
Isolation of mutant T lymphocytes with defects in capacitative calcium entry.
Isolation of temperature-sensitive diphtheria toxins in yeast and their effects on Drosophila cells.
Isolation of the lethal factor of diphtheria toxin by electrophoresis in starch gel.
Isolation of variants of Chinese hamster ovary cells with abnormally low levels of GSH: decreased ability to cleave endocytosed disulfide bonds.
Joining chain-expressing and -nonexpressing B cell populations in the mouse.
Keratinocytes Function as Accessory Cells for Presentation of Endogenous Antigen Expressed in the Epidermis.
Killing of cultured hepatocytes by conjugates of asialofetuin and EGF linked to the A chains of ricin or diphtheria toxin.
Kinetic intermediate reveals staggered pH-dependent transitions along the membrane insertion pathway of the diphtheria toxin T-domain.
Kinetics of adenosinediphosphoribosylation of elongation factor 2 in cells exposed to diphtheria toxin.
Kinetics of alpha 2-macroglobulin endocytosis and degradation in mutant and wild-type Chinese hamster ovary cells.
Kinetics of diphtheria toxin formation.
Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes.
Kinetics of protein synthesis inactivation by diphtheria toxin in toxin-resistant L cells. Evidence for a low efficiency receptor-mediated transport system.
Langerhans cells are not required for graft-versus-host disease.
Langerhans cells are required for UVR-induced immunosuppression.
Langerhans cells prevent subbasal nerve damage and upregulate neurotrophic factors in dry eye disease.
Langerhans cells regulate cutaneous innervation density and mechanical sensitivity in mouse footpad.
Langerhans cells--revisiting the paradigm using genetically engineered mice.
Langerin+ CD8?+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection.
Langerin+ dermal dendritic cells are critical for CD8+ T cell activation and IgH ?-1 class switching in response to gene gun vaccines.
Large-scale purification and characterization of the exotoxin of Pseudomonas aeruginosa.
Late direct and transneuronal effects in mice with targeted expression of a toxin gene to D1 dopamine receptor neurons.
Learned arbitrary responses to light in mice without rods or cones.
Lens structures exist transiently in development of transgenic mice carrying an alpha-crystallin-diphtheria toxin hybrid gene.
Lesions of cholinergic pedunculopontine tegmental nucleus neurons fail to affect cocaine or heroin self-administration or conditioned place preference in rats.
Letter: Diphtheria toxin in cancer therapy.
Lgr5-positive cells are cancer stem cells in skin squamous cell carcinoma.
Lgr5-Positive Cells are Cancer-Stem-Cell-Like Cells in Gastric Cancer.
Ligand interactions of diphtheria toxin. I. Binding and hydrolysis of NAD.
Ligand interactions of diphtheria toxin. II. Relationships between the NAD site and the P site.
Ligand interactions of diphtheria toxin. III. Direct photochemical cross-linking of ATP and NAD to toxin.
Ligand-toxin hybrids directed to the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein exhibit lower toxicity than native Pseudomonas exotoxin.
Limitations of Foxp3(+) Treg depletion following viral infection in DEREG mice.
Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing.
Limited role of CD4+Foxp3+ regulatory T cells in the control of experimental cerebral malaria.
Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice.
Limiting values for antibody; antigen ratio in the combination of diphtheria toxin with split antitoxic pseudoglobulin.
Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.
Linked thermal and solute perturbation analysis of cooperative domain interactions in proteins. Structural stability of diphtheria toxin.
Lipid interaction of diphtheria toxin and mutants with altered fragment B. 1. Liposome aggregation and fusion.
Lipid interaction of diphtheria toxin and mutants with altered fragment B. 2. Hydrophobic photolabelling and cell intoxication.
Lipid interaction of diphtheria toxin and mutants. A study with phospholipid and protein monolayers.
Lipopolyamine treatment increases the efficacy of intoxication with saporin and an anticancer saporin conjugate.
Liposomal Dual Delivery of Both Polysaccharide and Protein Antigens.
Liposome-mediated delivery of antiviral agents to human immunodeficiency virus-infected cells.
Liposome-mediated delivery of ribosome inactivating proteins to cells in vitro.
Liposomes as a means to introduce fragment A of diphtheria toxin into cells.
Local "on-demand" generation and function of antigen-specific Foxp3+ regulatory T cells.
Local control of granule cell generation by cerebellar Purkinje cells.
Local treatment of brain tumors with targeted chimera cytotoxic proteins.
Localization in diphtheria toxin fragment B of a region that induces pore formation in planar lipid bilayers at low pH.
Localization of a critical diphtheria toxin-binding domain to the C-terminus of the mature heparin-binding EGF-like growth factor region of the diphtheria toxin receptor.
Localization of diphtheria toxin nuclease activity to fragment A.
Localization of the active site of diphtheria toxin.
Localization of the diphtheria toxin receptor-binding domain to the carboxyl-terminal Mr approximately 6000 region of the toxin.
Localization of the sites of ADP-ribosylation and GTP binding in the eukaryotic elongation factor EF-2.
Locating a residue in the diphtheria toxin channel.
Long-Term Depletion of Conventional Dendritic Cells Cannot Be Maintained in an Atherosclerotic Zbtb46-DTR Mouse Model.
Long-term inhibition of clinical and laboratory human immunodeficiency virus strains in human T-cell lines containing an HIV-regulated diphtheria toxin A chain gene.
Long-term persistence of anti-diphtheria toxin antibodies among adults in Israel. Implications for vaccine policy.
Long-term prevention of chronic allograft rejection by regulatory T-cell immunotherapy involves host Foxp3-expressing T cells.
Long-term sustainable dendritic cell-specific depletion murine model for periodontitis research.
Loss of diphthamide pre-activates NF-?B and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.
Loss of Endogenously Cycling Adult Cardiomyocytes Worsens Myocardial Function.
Low baseline antibody level to diphtheria is associated with poor response to conjugated pneumococcal vaccine in adults.
Low pH induces a hydrophobic domain in the tetanus toxin molecule.
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol.
Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11.
Lung Angiogenesis Requires CD4(+) Forkhead Homeobox Protein-3(+) Regulatory T Cells.
Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity.
Lymph Node Transplantation Decreases Swelling and Restores Immune Responses in a Transgenic Model of Lymphedema.
Lysophospholipid enhancement of human T cell sensitivity to diphtheria toxin by increased expression of heparin-binding epidermal growth factor.
Lysozyme M-Positive Monocytes Mediate Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
M2 macrophages promote wound-induced hair neogenesis.
Macrophage depletion disrupts immune balance and energy homeostasis.
Macrophage recruitment and epithelial repair following hair cell injury in the mouse utricle.
Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice.
Macrophage/monocyte depletion by clodronate, but not diphtheria toxin, improves renal ischemia/reperfusion injury in mice.
Macrophages are essential contributors to kidney injury in murine cryoglobulinemic membranoproliferative glomerulonephritis.
Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury.
Macrophages are required for cell death and tissue remodeling in the developing mouse eye.
Macrophages directly mediate diabetic renal injury.
Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury.
mADP-RTs: versatile virulence factors from bacterial pathogens of plants and mammals.
Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
Maintenance of vascular integrity by pericytes is essential for normal kidney function.
Maladaptive proximal tubule repair: cell cycle arrest.
Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
Management of otitis media: 2000 and beyond.
Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins.
Manganese-dependent regulation of the endocarditis-associated virulence factor EfaA of Enterococcus faecalis.
Mapping the enzymatic active site of Pseudomonas aeruginosa exotoxin A.
Mapping the membrane topography of the TH6-TH7 segment of the diphtheria toxin T-domain channel.
Mast Cells Modulate Antigen-Specific CD8+ T Cell Activation During LCMV Infection.
Mathematical modeling of mutant transferrin-CRM107 molecular conjugates for cancer therapy.
Maturation of mouse NK cells is a four-stage developmental program.
Mature DC from skin and skin-draining LN retain the ability to acquire and efficiently present targeted antigen.
Measuring immunoglobulin g antibodies to tetanus toxin, diphtheria toxin, and pertussis toxin with single-antigen enzyme-linked immunosorbent assays and a bead-based multiplex assay.
Mechanism of action of phenomycin: comparative study with diphtheria toxin.
Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo.
Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones.
Mechanism of Diphtheria Toxin Catalytic Domain Delivery to the Eukaryotic Cell Cytosol and the Cellular Factors that Directly Participate in the Process.
Mechanism of insertion of diphtheria toxin: peptide entry and pore size determinations.
Mechanism of metal ion activation of the diphtheria toxin repressor DtxR.
Mechanistic aspects of the deoxyribonuclease activity of diphtheria toxin.
Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis.
Mediation of inflammatory ascites formation induced by macromolecules in mice.
Melanin Concentrating Hormone Signaling Deficits in Schizophrenia: Association With Memory and Social Impairments and Abnormal Sensorimotor Gating.
Melanin-concentrating hormone neurons specifically promote rapid eye movement sleep in mice.
Membrane Association of the Diphtheria Toxin Translocation Domain Studied by Coarse-Grained Simulations and Experiment.
Membrane Interaction of Botulinum Neurotoxin A Translocation (T) Domain: THE BELT REGION IS A REGULATORY LOOP FOR MEMBRANE INTERACTION.
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants.
Membrane protein insertion regulated by bringing electrostatic and hydrophobic interactions into play. A case study with the translocation domain of diphtheria toxin.
Membrane topography of the T domain of diphtheria toxin probed with single tryptophan mutants.
Membrane translocation and channel-forming activities of diphtheria toxin are blocked by replacing isoleucine 364 with lysine.
Membrane translocation assay based on proteolytic cleavage: application to diphtheria toxin T domain.
Membrane translocation of charged residues at the tips of hydrophobic helices in the T domain of diphtheria toxin.
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region.
Membrane translocation of diphtheria toxin carrying passenger protein domains.
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery.
Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.
Membrane-insertion fragments of Bcl-xL, Bax, and Bid.
Meningococcal quadrivalent (serogroups A, C, w135, and y) conjugate vaccine (Menveo): in adolescents and adults.
Mesencephalic dopaminergic neurons are essential for modafinil-induced arousal.
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle.
Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes.
Metal binding studies and EPR spectroscopy of the manganese transport regulator MntR.
Metal stoichiometry and functional studies of the diphtheria toxin repressor.
Methotrexate-poly(lysine) as a selective agent for mutants of Chinese hamster ovary cells defective in endocytosis.
Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
Methylamine facilitates demonstration of specific uptake of diphtheria toxin by CHO cell and toxin-resistant CHO cell mutants.
Methylamine stimulates the action of ricin toxin but inhibits that of diphtheria toxin.
Methylglyoxal in beverages and foods: its mutagenicity and carcinogenicity.
Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. I. Studies on factors affecting the toxin and antitoxin titration.
Micro cell culture method for determination of diphtheria toxin and antitoxin titres using VERO cells. II. Comparison with the rabbit skin method and practical application for seroepidemiological studies.
Microbiological changes and diversity in autochthonous non-toxigenic Corynebacterium diphtheriae isolated in France.
Microglia can be induced by IFN-gamma or IL-4 to express neural or dendritic-like markers.
Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats.
Microglia limit the expansion of ?-amyloid plaques in a mouse model of Alzheimer's disease.
Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.
Microinjection of macromolecules into leukemic cells by cell fusion technique: search for intracellular growth-suppressive factors.
Microsecond Simulations of the Diphtheria Toxin Translocation Domain in Association with Anionic Lipid Bilayers.
Midline signaling regulates kidney positioning but not nephrogenesis through Shh.
Mitochondrial changes induced by diphtheria toxin in chicken embryo heart cell cultures.
Mitochondrial swelling induced by diphtheria toxin in cell cultures.
Mitochondrial swelling induced by diphtheria toxin in vivo: a comparison with the action of some other bacterial toxins.
Mitochondrial swelling induced by diphtheria toxin. The behaviour of citrate in intoxicated cells.
Mn(II) Binding by the Anthracis Repressor from Bacillus anthracis.
Mode of action of diphtheria toxin on protein synthesis. I. Effect of diphtheria toxin on C14-amino acids incorporation into microsomes and mitochondria in vitro.
Mode of inhibition of diphtheria toxin by ammonium chloride.
Modification of diphtheria toxin by NAD.
Modification of the cell surface with neuraminidase increases the sensitivities of cells to diphtheria toxin and Pseudomonas aeruginosa exotoxin.
Modified DT-IL2 fusion toxin targeting uniquely IL2Ralpha expressing leukemia cell lines - Construction and characterization.
Modular drug transporters with diphtheria toxin translocation domain form edged holes in lipid membranes.
Modulation of axon diameter and neurofilaments by hypomyelinating Schwann cells in transgenic mice.
Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells.
Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway.
Modulation of Wnt-specific colon cancer cell kill by butyrate and lithium.
Molecular attributes of conjugate antigen influence function of antibodies induced by anti-nicotine vaccine in mice and non-human primates.
Molecular characterization of diphtheria toxin repressor (dtxR) genes present in nontoxigenic Corynebacterium diphtheriae strains isolated in the United Kingdom.
Molecular characterization of key diphtheria toxin:receptor interactions.
Molecular cloning and characterization of chick CD9.
Molecular cloning and characterization of the Caenorhabditis elegans elongation factor 2 gene (eft-2).
Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.
Molecular cloning and expression of gene fragments from corynebacteriophage beta encoding enzymatically active peptides of diphtheria toxin.
Molecular Cloning, Structural Modeling and the Production of Soluble Triple-Mutated Diphtheria Toxoid (K51E/G52E/E148K) Co-expressed with Molecular Chaperones in Recombinant Escherichia coli.
Molecular epidemiology of diphtheria.
Molecular genetic evidence for early evolutionary origin of budding peptidoglycan-less eubacteria.
Molecular mechanism of domain swapping in proteins: an analysis of slower motions.
Molecular modification of a recombinant, bivalent anti-human CD3 immunotoxin (Bic3) results in reduced in vivo toxicity in mice.
Molecular, functional and structural properties of an archaebacterial elongation factor 2.
Monensin blocks the transport of diphtheria toxin to the cell cytoplasm.
Monensin intercalation in liposomes: effect on cytotoxicities of ricin, Pseudomonas exotoxin A and diphtheria toxin in CHO cells.
Monitoring the therapy of human tumor xenografts in nude mice by the use of lactate dehydrogenase.
Mono(ADP-ribosyl)ation of 2'-deoxyguanosine residue in DNA by an apoptosis-inducing protein, pierisin-1, from cabbage butterfly.
Monoclonal antibodies against diphtheria toxin fragment A. Characterization and introduction into living cells.
Monoclonal antibodies against Vero cells that protect against diphtheria toxin.
Monoclonal antibody against diphtheria toxin. Effect on toxin binding and entry into cells.
Monoclonal antibody analysis of diphtheria toxin--I. Localization of epitopes and neutralization of cytotoxicity.
Monoclonal antibody analysis of diphtheria toxin--II. Inhibition of ADP-ribosyl-transferase activity.
Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth.
Monocyte-Derived Dendritic Cells Impair Early Graft Function Following Allogeneic Islet Transplantation.
Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques.
Monocytes Control Second-Phase Neutrophil Emigration in Established Lipopolysaccharide-induced Murine Lung Injury.
Monocytes Promote Crescent Formation in Anti-Myeloperoxidase Antibody-Induced Glomerulonephritis.
Monolith affinity chromatography for the rapid quantification of a single-chain variable fragment immunotoxin.
Monte Carlo simulations of tBid association with the mitochondrial outer membrane.
Morphological abnormalities, neonatal mortality, and reproductive abnormalities in mice transgenic for diphtheria toxin genes that are driven by the promoter for adipocyte lipid binding protein.
Morphological and physiological consequences of the selective elimination of rod photoreceptors in transgenic mice.
Morphological remodeling during recovery of the neuromuscular junction from terminal Schwann cell ablation in adult mice.
Morphometric evidence from C-synapses for phased Nissl body response in alpha-motoneurones retrogradely intoxicated with diphtheria toxin.
Mosaic regularity of horizontal cells in the mouse retina is independent of cone photoreceptor innervation.
Mosquito inoculation: an alternative bioassay for toxins.
Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
Mouse models demonstrating the role of stem/progenitor cells in gastric carcinogenesis.
Mouse Models for the Evaluation of Osteocyte Functions.
MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer.
Mucosal vaccination against diphtheria using starch microparticles as adjuvant for cross-reacting material (CRM197) of diphtheria toxin.
Multi-epitope insert modulates solubility-based and chromatographic purification of human papilloma virus 16 L1-based vaccine without inhibiting virus-like particle assembly.
Multifunctional protein nanocarriers for targeted nuclear gene delivery in nondividing cells.
Multilocus sequence typing of Corynebacterium ulcerans provides evidence for zoonotic transmission and for increased prevalence of certain sequence types among toxigenic strains.
Multiple sigma factor genes in Brevibacterium lactofermentum: characterization of sigA and sigB.
Multiplexed measurement of serum antibodies using an array biosensor.
Murine monoclonal antibodies neutralizing the cytotoxic activity of diphtheria toxin.
Murine spontaneous T-cell leukemia constitutively expressing IL-2 receptor--a model for human T-cell malignancies expressing IL-2 receptor.
Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury.
Muscle-specific cell ablation conditional upon Cre-mediated DNA recombination in transgenic mice leads to massive spinal and cranial motoneuron loss.
Mutagenic activities of heterocyclic amines in Chinese hamster lung cells in culture.
Mutagenic activity of heterocyclic amines in Chinese hamster lung cells with diphtheria toxin resistance as a marker.
Mutagenic activity of norharman and harman in Chinese hamster lung cells in assays with diphtheria toxin resistance as a marker.
Mutagenic Deimmunization of Diphtheria Toxin for Use in Biologic Drug Development.
Mutagenic effect of nitrilotriacetic acid on cultured human cells.
Mutagenic properties of 2-amino-N6-hydroxyadenine in Salmonella and in Chinese hamster lung cells in culture.
Mutagenicity of instant coffee on cultured Chinese hamster lung cells.
Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosoethylurea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus.
Mutagenicity of quercetin in Chinese hamster lung cells in culture.
Mutant Chinese hamster ovary cells pleiotropically defective in receptor-mediated endocytosis.
Mutant with diphtheria toxin receptor and acidification function but defective in entry of toxin.
Mutated form (G52E) of inactive diphtheria toxin CRM197: molecular simulations clearly display effect of the mutation to NAD binding.
Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans.
Mutation in the structural gene for diphtheria toxin carried by temperate phage .
Mutation induction by okadaic acid, a protein phosphatase inhibitor, in CHL cells, but not in S. typhimurium.
Mutation of specific acidic residues of the CNF1 T domain into lysine alters cell membrane translocation of the toxin.
Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain.
Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity.
Mutations in diphtheria toxin to improve immunotoxin selectivity and understand toxin entry into cells.
Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses.
Mutations of corynephage beta that affect the yield of diphtheria toxin.
Mutual interactions between DTaP-IPV and Haemophilus influenzae type b (Hib)-conjugated vaccines in laboratory animal models.
Myelin sheath remodelling in remyelinated rat sciatic nerve.
Myeloid cells activate iNKT cells to produce IL-4 in the thymic medulla.
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer.
Myocardial differentiation is dependent upon endocardial signaling during early cardiogenesis in vitro.
MyoD-expressing progenitors are essential for skeletal myogenesis and satellite cell development.
Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury.
NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD.
NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,.
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice.
Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Nanoparticulate delivery of suicide DNA to murine prostate and prostate tumors.
Nasopharyngeal colonization with Streptococcus pneumoniae triggers dendritic cell dependent antibody responses against invasive disease in mice.
Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection.
Natural resistance against diphtheria toxin.
Naturally occurring disseminated group B streptococcus infections in postnatal rats.
Needle-Free Dermal Delivery of a Diphtheria Toxin CRM197 Mutant on Potassium-Doped Hydroxyapatite Microparticles.
Negative selection with the Diphtheria toxin A fragment gene improves frequency of Cre-mediated cassette exchange in ES cells.
Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.
Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney.
Neural blastocyst complementation enables mouse forebrain organogenesis.
Neural stem cells improve memory in an inducible mouse model of neuronal loss.
Neurofilament reorganisation and neurofilament antigen redistribution in spinal motoneurones following retrograde axonal transport of diphtheria toxin.
Neuropathy in miniature swine after administration of the mutant diphtheria toxin-based immunotoxin, pCD3-CRM9.
Neutralization of diphtheria toxin by human immunoglobulin classes and subunits.
Neutralization of diphtheria toxin in living cells by microinjection of antifragment A contained within resealed erythrocyte ghosts.
Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.
New diphtheria toxin repressor types depicted in a Romanian collection of Corynebacterium diphtheriae isolates.
New form of diphtheria toxin.
New inducible mast cell-deficient mouse model (Mcpt5/Cma1DTR).
New method for the large-scale preparation of diphtheria toxoid: purification of toxin.
New protein cross-linking reagents that are cleaved by mild acid.
NG2 glia regulate brain innate immunity via TGF-?2/TGFBR2 axis.
NGS-based phylogeny of diphtheria-related pathogenicity factors in different Corynebacterium spp. implies species-specific virulence transmission.
Ninjin'yoeito, a traditional Japanese Kampo medicine, suppresses the onset of anhedonia induced by dysfunction in the striatal dopamine receptor type 2-expressing medium spiny neurons.
NK cell function in severe combined immunodeficiency (SCID): evidence of a common T and NK cell defect in some but not all SCID patients.
NMR study of mutations of glycine-52 of the catalytic domain of diphtheria toxin.
NO2 inhalation induces maturation of pulmonary CD11c+ cells that promote antigenspecific CD4+ T cell polarization.
Non-toxigenic Corynebacterium ulcerans sequence types 325 and 339 isolated from two dogs with ulcerative lesions in Italy.
Non-toxigenic tox gene-bearing Corynebacterium ulcerans in a traumatic ulcer from a human case and his asymptomatic dog.
Nonbone Marrow CD34+ Cells Are Crucial for Endothelial Repair of Injured Artery.
Nonhuman Primate Testing of the Impact of Different Regulatory T Cell Depletion Strategies on Reactivation and Clearance of Latent Simian Immunodeficiency Virus.
Notes on the Leucocyte-Reaction during the Immunisation of the Horse and Goat with Diphtheria Toxin.
Notes on the Production of Immunity to Diphtheria Toxin.
Novel bacterial ADP-ribosylating toxins: structure and function.
Novel basophil- or eosinophil-depleted mouse models for functional analyses of allergic inflammation.
Novel blockade of cell surface expression of virus glycoproteins by leucinostatin A.
Novel cholix toxin variants, ADP-ribosylating toxins in Vibrio cholerae non-O1/non-O139 strains, and their pathogenicity.
Novel cytotoxic vectors based on adeno-associated virus.
Novel expression vectors enabling induction of gene expression by small-interfering RNAs and microRNAs.
Novel Furin Inhibitors with Potent Anti-infectious Activity.
Novel immunotherapeutic agents and small molecule antagonists of signalling kinases for the treatment of metastatic melanoma.
Novel method for substance injection into the cell by laser beam--a study of the injection volume.
Novel Microglia Depletion Systems: A Genetic Approach Utilizing Conditional Diphtheria Toxin Receptor Expression and a Pharmacological Model Based on the Blocking of Macrophage Colony-Stimulating Factor 1 Receptor.
Nox2+ Myeloid cells drive vascular inflammation and endothelial dysfunction in heart failure after myocardial infarction via angiotensin II receptor type 1.
NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.
Nucleotide binding to elongation factor 2 inactivated by diphtheria toxin.
Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta.
Observations on crystalline diphtheria toxin: the optical density per Lf unit at 276 m-omega.
Observations on the structure of diphtheria toxin.
Occurrence of diphthamide in archaebacteria.
Occurrence of tryptophan in the enzymically active site of diphtheria toxin fragment A.
Oculomotor nerve guidance and terminal branching requires interactions with differentiating extraocular muscles.
OHC-TRECK: A Novel System Using a Mouse Model for Investigation of the Molecular Mechanisms Associated with Outer Hair Cell Death in the Inner Ear.
Oligomerization of a 45 kilodalton fragment of diphtheria toxin at pH 5.0 to a molecule of 20-24 subunits.
Oligomerization of membrane-bound diphtheria toxin (CRM197) facilitates a transition to the open form and deep insertion.
On diphtheria toxin fragment A release into the cytosol-Cytochalasin D effect and involvement of actin filaments and eukaryotic elongation factor 2.
On the alleged high sensitivity of mouse Ehrlich-Lettre ascites tumor cells to diphtheria toxin.
On the antigenic composition of diphtheria toxin and toxoid.
On the Estimation of Free Diphtheria Toxin: with reference to the relations existing between lethal doses, lethal times and loss in weight of the guinea-pig.
On the formation of diphtheria toxin in saliva by C. diphtheriae.
On the lack of agreement of the constant toxin and constant antitoxin flocculation reactions of diphtheria toxin and equine antitoxin.
On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.
On the nature of cellular ADP-ribosyltransferase from rat liver specific for elongation factor 2.
ON THE NATURE OF DIPHTHERIA TOXIN.
On the pathogenesis of diphtheria. III. On the formation of diphtheria toxin in fresh human saliva.
On the pathogenesis of diphtheria. IV. On the occurrence of diphtheria toxin in the saliva of diphtheria patients.
On Variation in Weight of Normal Guinea-pigs in relation to the Estimation of Free Diphtheria Toxin.
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell.
Ontak-like human IL-2 fusion toxin.
Opposing Effects of Acute Versus Chronic Blockade of Frontal Cortex Somatostatin-Positive Inhibitory Neurons on Behavioral Emotionality in Mice.
Optic nerve fibre lesions in adult cats: pattern of recovery of spatial vision.
Optimal route of diphtheria toxin administration to eliminate native nephron progenitor cells in vivo for kidney regeneration.
Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy.
Optimization of casein-based semisynthetic medium for growing of toxigenic Corinebacterium diphtheriae in a fermenter.
Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach.
Optimization of the anti-(human CD3) immunotoxin DT389-scFv(UCHT1) N-terminal sequence to yield a homogeneous protein.
Optimization of the Expression of DT386-BR2 Fusion Protein in Escherichia coli using Response Surface Methodology.
Optimizing denileukin diftitox (Ontak) therapy.
Optogenetic Inhibition of CGRP? Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain.
Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation.
Oral and parenteral immunization with synthetic retro-inverso peptides induce antibodies that cross-react with native peptides and parent antigens.
Oral immunization against diphtheria and tetanus infections by fluid diphtheria and tetanus toxoids.
Oral immunogenicity of tomato-derived sDPT polypeptide containing Corynebacterium diphtheriae, Bordetella pertussis and Clostridium tetani exotoxin epitopes.
Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice.
Oral vaccination against diphtheria using polyacryl starch microparticles as adjuvant.
Organ-specific binding of a thyrotropin-releasing hormone-diphtheria toxin complex after intravenous administration to rats.
Organization of diphtheria toxin in membranes. A hydrophobic photolabeling study.
Organization of diphtheria toxin in membranes: a hydrophobic photolabeling study
Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study.
Orientation of the Diphtheria Toxin Channel in Lipid Bilayers.
Orientation of the tox gene in the prophage of corynebacteriophage beta.
Origins of metal ion selectivity in the DtxR/MntR family of metalloregulators.
Osteoclast progenitors reside in the peroxisome proliferator-activated receptor ?-expressing bone marrow cell population.
Outbreak with clonally related isolates of Corynebacterium ulcerans in a group of water rats.
Ovalbumin fused with diphtheria toxin protects mice from ovalbumin induced anaphylactic shock.
Ovarian steroid hormone-regulated uterine remodeling occurs independently of macrophages in mice.
OVCA1: tumor suppressor gene.
Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins.
Overexpression and purification of the recombinant diphtheria toxin variant CRM197 in Escherichia coli.
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In?Vivo.
Oxidized ATP protection against anthrax lethal toxin.
P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice.
p53 Plays a Key Role in the Apoptosis of Human Ovarian Cancer Cells Induced by Adenovirus-Mediated CRM197.
PAI-1 Promotes the Accumulation of Exudate Macrophages and Worsens Pulmonary Fibrosis Following Type II Alveolar Epithelial Cell Injury.
Pancreatic Beta cells in very old mice retain capacity for compensatory proliferation.
Pancreatic mesenchyme regulates epithelial organogenesis throughout development.
Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia.
Paraventricular nucleus Sim1 neuron ablation mediated obesity is resistant to high fat diet.
PARP inhibitors: polypharmacology versus selective inhibition.
Partial ablation of the orexin field induces a sub-narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration.
Partial characterization of a cell proliferation-inhibiting protein produced by Helicobacter pylori.
Partial characterization of diphtheria toxin and its subunits.
Participation of lysine 516 and phenylalanine 530 of diphtheria toxin in receptor recognition.
Pasteurella multocida toxin as a transporter of non-cell-permeating proteins.
Path Similarity Analysis: A Method for Quantifying Macromolecular Pathways.
Pathological changes in the optic chiasm of the cat following local injection of diphtheria toxin.
Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation.
Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration.
PDGF-Producing CD4+ Foxp3+ Regulatory T Lymphocytes Promote Lung Fibrosis.
Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response.
Penetration of protein toxins into cells.
Pentapeptide commonality between Corynebacterium diphtheriae toxin and the Homo sapiens proteome.
Pentapeptide sharing between Corynebacterium diphtheria toxin and the human neural protein network.
Pentavalent pneumococcal oligosaccharide conjugate vaccine PncCRM is well-tolerated and able to induce an antibody response in infants.
Peptide Probes Reveal a Hydrophobic Steric Ratchet in the Anthrax Toxin Protective Antigen Translocase.
Peptide toxins directed at the matrix dissolution systems of cancer cells.
Peptide-Protein Conjugation and Characterization to Develop Vaccines for Group A Streptococcus.
Peptides derived from a short stretch of diphtheria toxin bind to heparin-binding epidermal growth factor-like growth factor.
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol.
Peptidyl transferase activity in rat skeletal muscle ribosomes after protein restriction.
Percutaneous sensitization is limited by in situ inhibition of cutaneous dendritic cell migration through skin-resident regulatory T cells.
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.
Perinatal ablation of the mouse lens causes multiple anterior chamber defects.
Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation.
Peripheral inflammatory pain sensitisation is independent of mast cell activation in male mice.
Peripheral nerve segmental demyelination induced by intraneural diphtheria toxin injection. I. Effect of hydrocortisone as measured by muscle twitch tension.
Peripheral nerve segmental demyelination induced by intraneural diphtheria toxin injection. Sodium Na 24 and carbon 14-labeled inulin kinetics in diphtheria toxin-injected nerve and the effect of hydrocortisone.
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin.
Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells.
PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells.
pH dependent insertion of a diphtheria toxin B fragment peptide into the lipid membrane: a conformational analysis.
pH-dependence of the phospholipid interaction of diphtheria-toxin fragments.
pH-dependent bilayer destabilization and fusion of phospholipidic large unilamellar vesicles induced by diphtheria toxin and its fragments A and B.
pH-dependent insertion of proteins into membranes: B-chain mutation of diphtheria toxin that inhibits membrane translocation, Glu-349----Lys.
pH-triggered conformational switching along the membrane insertion pathway of the diphtheria toxin T-domain.
pH-triggered conformational switching of the diphtheria toxin T-domain: the roles of N-terminal histidines.
Pharmacokinetic analysis of immunotoxin uptake in solid tumors: role of plasma kinetics, capillary permeability, and binding.
Pharmacokinetics of the recombinant fusion protein DAB486IL-2 in animal models.
Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials.
Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia.
Phase I Study of a Bispecific Ligand-Directed Toxin Targeting CD22 and CD19 (DT2219) for Refractory B-cell Malignancies.
Phase I study of the immunogenicity and safety of conjugated Hemophilus influenzae type b vaccines in the elderly.
Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers.
Phase I trial of a genetically engineered interleukin-2 fusion toxin (DAB486IL-2) as a 6 hour intravenous infusion in patients with hematologic malignancies.
Phase I trial of a ligand fusion-protein (DAB389IL-2) in lymphomas expressing the receptor for interleukin-2.
Phase I trial of an interleukin-2 (IL-2) fusion toxin (DAB486IL-2) in hematologic malignancies expressing the IL-2 receptor.
Phase I trial of an interleukin-2 fusion toxin (DAB486IL-2) in hematologic malignancies: complete response in a patient with Hodgkin's disease refractory to chemotherapy.
Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission.
Phase II clinical studies of denileukin diftitox diphtheria toxin fusion protein in patients with previously treated chronic lymphocytic leukemia.
Phase II study of denileukin diftitox for relapsed/refractory B-Cell non-Hodgkin's lymphoma.
Phase II study of E7777 in Japanese patients with relapsed/refractory peripheral and cutaneous T-cell lymphoma.
Phospholipid alterations in liver and serum of rabbits treated with diphtheria toxin.
Phosphorylated neurofilament antigen redistribution in intercostal nerve subsequent to retrograde axonal transport of diphtheria toxin.
Phosphorylation, desensitization and internalization of human alpha1B-adrenoceptors induced by insulin-like growth factor-I.
Photic Regulation of Circadian Rhythms and Voluntary Ethanol Intake: Role of Melanopsin-expressing Intrinsically Photosensitive Retinal Ganglion Cells.
Photoaffinity labeling of diphtheria toxin fragment A with 8-azidoadenosyl nicotinamide adenine dinucleotide.
Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148.
Photolabeling of Glu-129 of the S-1 subunit of pertussis toxin with NAD.
Photolabelling of cholera toxin by NAD+.
Physicochemical analysis of purified diphtheria toxoids: is toxoided then purified the same as purified then toxoided?
Physicochemical and immunochemical techniques predict the quality of diphtheria toxoid vaccines.
Physicochemical characterisation of the oligosaccharide component of vaccines.
Physicochemical characterisation, immunogenicity and protective efficacy of a lead streptococcal vaccine: progress towards Phase I trial.
PI3KC2?, a class II PI3K, is required for dynamin-independent internalization pathways.
Pilot trial of a pentavalent pneumococcal polysaccharide/protein conjugate vaccine in Gambian infants.
Pinocytosis of diphtheria toxin by different types of human cells cultured in vitro.
Pinocytosis of some exotoxins by leucocytes. Pinocytosis of diphtheria toxin and of dick erythrotoxin.
Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual.
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
Pneumococcal Surface Protein A does not affect the immune responses to a combined diphtheria tetanus and pertussis vaccine in mice.
Pocket analysis of the full-length cholix toxin. An assessment of the structure-dynamics of the apo catalytic domain.
Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.
Pollen ablation of transgenic tobacco plants by expression of the diphtheria toxin A-chain gene under the control of a putative pectin esterase promoter from Chinese cabbage.
Pollen-specific expression of the Arabidopsis thaliana alpha 1-tubulin promoter assayed by beta-glucuronidase, chloramphenicol acetyltransferase and diphtheria toxin reporter genes.
Polycyclic hydrocarbons induction of diphtheria toxin-resistant mutants in human cells.
Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore.
Polymerase chain reaction assay for diagnosis of potentially toxinogenic Corynebacterium diphtheriae strains: correlation with ADP-ribosylation activity assay.
Polymerase chain reaction for screening clinical isolates of corynebacteria for the production of diphtheria toxin.
Polymorphisms of CD3epsilon in cynomolgus and rhesus monkeys and their relevance to anti-CD3 antibodies and immunotoxins.
Polyphosphate-mediated protection from cellular intoxication with Clostridium difficile toxin B.
Population genomics and antimicrobial resistance in Corynebacterium diphtheriae.
Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells.
Positive-negative-selection-mediated gene targeting in rice.
Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins.
Possible Cross-Reactivity between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and Death.
Potency assay of diphtheria antitoxin in Vero cell microcultures.
Potency of a human monoclonal antibody to diphtheria toxin relative to equine diphtheria anti-toxin in a guinea pig intoxication model.
Potency of a Human Monoclonal Antibody to Diphtheria Toxin Relative to Equine Diphtheria Anti-toxin in an Animal Model.
Potent diphtheria toxin within the cells of C. diphtheriae.
Potent in vitro antitumor activity of B-subunit of Shiga toxin conjugated to the diphtheria toxin against breast cancer.
Potent killing of HBV-related hepatocellular carcinoma by a chimeric protein of anti-HBsAg single-chain antibody and truncated Bid.
Potent mutagenic activity of nitropyrenes on Chinese hamster lung cells with diphtheria toxin resistance as a selective marker.
Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates.
Potentiation of ricin cytotoxicity by liposomal monensin under in vitro and in vivo conditions.
Pre-clinical and Clinical Implications of "Inside-Out" vs. "Outside-In" Paradigms in Multiple Sclerosis Etiopathogenesis.
Pre-clinical evaluation of a 15-valent pneumococcal conjugate vaccine (PCV15-CRM197) in an infant-rhesus monkey immunogenicity model.
Precise toxigenic ablation of intermediate cells abolishes the "battery" of the cochlear duct.
Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen.
Preclinical evaluation of group B streptococcal polysaccharide conjugate vaccines prepared with a modified diphtheria toxin and a recombinant duck hepatitis B core antigen.
Preclinical studies in rats and squirrel monkeys for safety evaluation of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1).
Preclinical studies on new proteins as carrier for glycoconjugate vaccines.
Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways.
Precursor in cotranslational secretion of diphtheria toxin.
Prediction of DtxR regulon: identification of binding sites and operons controlled by Diphtheria toxin repressor in Corynebacterium diphtheriae.
Preferential expression of osteocalcin-related protein mRNA in gonadal tissues of male mice.
Preferential inhibition of growth and protein synthesis in Rous sarcoma virus transformed cells by diphtheria toxin.
Preformed Wolffian duct regulates Müllerian duct elongation independently of canonical Wnt signaling or Lhx1 expression.
Pregnancy induces a fetal antigen-specific maternal T regulatory cell response that contributes to tolerance.
Preliminary crystallographic investigation of the protein toxin from corynebacterium diphtheriae.
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure.
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway.
Preparation and properties of diphtheria toxoids in submerged culture. IV. A revised method for the purification of diphtheria toxin.
Preparation of a diphtheria toxin-pullulan conjugate that elicits good IgG antibody production with poor IgE synthesis.
Preparation of a hybrid of fragment Fab' of antibody and fragment A of diphtheria toxin and its cytotoxicity.
Preparation of an immunotoxin for Acanthamoeba castellanii.
Preparation of Diphtheria and Pseudomonas Exotoxin A Immunotoxins and Evaluation of Their Cytotoxicity Effect on SK-BR-3, BT-474, and MDA-MB-231 Breast Cancer Cell Lines.
Preparation of diphtheria toxin fragment A coupled to hormone.
Preparation of diphtheria toxin solution requiring no control in the Schick test.
Preparation of Poly[lactic-co-glycolic] Acid Nanospheres and Its Role in Hepatoma Cells.
Preproglucagon Neurons in the Nucleus of the Solitary Tract are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food.
Presynaptic terminal loss from alpha-motoneurones following the retrograde axonal transport of diphtheria toxin.
Prevalence and correlates of diphtheria toxin antibodies among young adults in Israel.
Prevalence of diphtheria toxin antibodies in human sera from a cross-section of the Italian population.
Prevention of experimental myasthenia gravis by nasal administration of synthetic acetylcholine receptor T epitope sequences.
Prevention of Haemophilus influenzae type b infections in Apache and Navajo children.
Prevention of smooth muscle cell outgrowth from human atherosclerotic plaque by a recombinant cytotoxin specific for the epidermal growth factor receptor.
Primary structure at the site in beef and wheat elongation factor 2 of ADP-ribosylation by diphtheria toxin.
Primary structure of diphtheria toxin fragment B: structural similarities with lipid-binding domains.
Primary structure of elongation factor 2 around the site of ADP-ribosylation is highly conserved from archaebacteria to eukaryotes.
Prime-Pull Immunization with a Bivalent M-Protein and Spy-CEP Peptide Vaccine Adjuvanted with CAF®01 Liposomes Induces Both Mucosal and Peripheral Protection from covR/S Mutant Streptococcus pyogenes.
Priming of CD8+ and CD4+ T cells in experimental leishmaniasis is initiated by different dendritic cell subtypes.
Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin.
Probing the function of Drosophila melanogaster accessory glands by directed cell ablation.
Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives.
Proceedings: Effect of cyclic AMP on inhibition of amino acid incorporation into heart muscle by diphtheria toxin.
Process optimization for an industrial-scale production of Diphtheria toxin by Corynebacterium diphtheriae PW8.
Process optimization for enhanced production of diphtheria toxin by submerged cultivation.
Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine.
Production and evaluation of cytotoxic effects of DT386-BR2 fusion protein as a novel anti-cancer agent.
Production in Escherichia coli of recombinant COVID-19 spike protein fragments fused to CRM197.
Production of a conjugate vaccine for Salmonella enterica serovar Typhi from Citrobacter Vi.
Production of CETD transgenic mouse line allowing ablation of any type of specific cell population.
Production of diphtheria toxin by selected isolates of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis.
Production of diphtheria toxin by the submerged culture method.
Production of diphtheria toxin CRM228 in B. subtilis.
Production of diphtheria toxin in submerged culture.
Production of dystrophic lesions in skeletal muscles of Dutch rabbit by diphtheria toxin.
Production of exoenzyme S by clinical isolates of Pseudomonas aeruginosa.
Production of high-titre diphtheria toxin in baffled shake flasks.
Production of IgY polyclonal antibody against diphtheria toxin and evaluation of its neutralization effect by Vero cell assay.
Production of recombinant DTctGMCSF fusion toxin in a baculovirus expression vector system for biotherapy of GMCSF-receptor positive hematologic malignancies.
Production of Viral Vectors with Suicide Genes by Utilizing the Intron-Splicing Mechanism of Insect Cells.
Production, characterization and cytotoxic properties of a diphtheria toxin-ciliary neurotrophic factor fusion protein.
Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma.
Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness.
Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice.
Proliferation inhibition of human cancer cells in combined use of electroporation with attenuated diphtheria toxin.
Prolongation of cardiac allograft survival in murine recipients treated with a diphtheria toxin-related interleukin-2 fusion protein.
Prolonged display or rapid internalization of the IgG-binding protein ZZ anchored to the surface of cells using the diphtheria toxin T domain.
Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch.
Prominin-1-expressing hepatic progenitor cells induce fibrogenesis in murine cholestatic liver injury.
Promising Fusion Protein Design to Target the U87 MG Glioma Cell Line.
Proof for the lack of diphtheria toxin in culture filtrates of Corynebacterium ulcerans strain ATCC 9015.
Properties of elongation factor-2 fragments obtained by partial proteolysis.
Properties of the purified elongation factor 2 in the thermoacidophilic archaebacterium Sulfolobus solfataricus.
Prospects of Bacterial and Plant Protein-based Immunotoxins for Treatment of Cancer.
Prostate-specific expression of the diphtheria toxin A chain (DT-A): studies of inducibility and specificity of expression of prostate-specific antigen promoter-driven DT-A adenoviral-mediated gene transfer.
Prostate-specific targeting using PSA promoter-based lentiviral vectors.
Protease Responsive Nanogels for Transcytosis across the Blood-Brain Barrier and Intracellular Delivery of Radiopharmaceuticals to Brain Tumor Cells.
Protection of mammalian cells from diphtheria toxin by exogenous nucleotides.
Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus.
Protective antitumor immunity induced by tumor cell lysates conjugated with diphtheria toxin and adjuvant epitope in mouse breast tumor models.
Protective effect of cell-permeable ceramide analogs against modeccin, ricin, Pseudomonas toxin, and diphtheria toxin.
Protective effect of L-carnitine in experimental intoxication with diphtheria toxin.
Protective immunogenicity of synthetic peptides selected from the amino acid sequence of Bordetella pertussis toxin subunit S1.
Protective immunogenicity of two synthetic peptides selected from the amino acid sequence of Bordetella pertussis toxin subunit S1.
Protective monoclonal antibodies to diphtheria toxin.
Protective role of macrophages in noninflammatory lung injury caused by selective ablation of alveolar epithelial type II Cells.
Protein engineering of diphtheria toxin. Development of receptor-specific cytotoxic agents for the treatment of human disease.
Protein synthesis in polymorphonuclear leucocytes in the presence of diphtheria toxin.
Protein toxin inhibitors of protein synthesis.
Protein translocation by bacterial toxin channels: a comparison of diphtheria toxin and colicin Ia.
Protein-disulfide isomerase-mediated reduction of the A subunit of cholera toxin in a human intestinal cell line.
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases.
Proteomics of diphtheria toxoid vaccines reveals multiple proteins that are immunogenic and may contribute to protection of humans against Corynebacterium diphtheriae.
Proximal tubule-derived colony stimulating factor-1 mediates polarization of renal macrophages and dendritic cells, and recovery in acute kidney injury.
Proximal Tubules Have the Capacity to Regulate Uptake of Albumin.
Prx1 Expressing Cells Are Required for Periodontal Regeneration of the Mouse Incisor.
Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A.
Pseudomonas aeruginosa exotoxin A interaction with eucaryotic elongation factor 2. Role of the His426 residue.
Pseudomonas aeruginosa exotoxin A: alterations of biological and biochemical properties resulting from mutation of glutamic acid 553 to aspartic acid.
Pseudomonas exotoxin exhibits increased sensitivity to furin when sequences at the cleavage site are mutated to resemble the arginine-rich loop of diphtheria toxin.
Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein.
Psoriasis: mechanisms and entry points for possible therapeutic interventions.
Pulmonary nodules due to Corynebacterium ulcerans.
Purification and characterization of peptide-elongation factor 2 (aEF-2) from an extremely halophilic archaebacterium Halobacterium halobium.
Purification and characterization of the diphtheria toxin repressor.
Purification and characterization of three elongation factors, EF-1 alpha, EF-1 beta gamma, and EF-2, from wheat germ.
PURIFICATION AND CRYSTALLIZATION OF DIPHTHERIA ANTITOXIN.
Purification and properties of an altered form of elongation factor 2 from mutant cells resistant to intoxication by diphtheria toxin.
Purification and some properties of exotoxin from Corynebacterium ulcerans strain ATCC 9015.
Purification and structural characterization of siderophore (corynebactin) from Corynebacterium diphtheriae.
Purification of a nitric oxide-stimulated ADP-ribosylated protein using biotinylated beta-nicotinamide adenine dinucleotide.
Purification of diphtheria toxin and diphtheria toxoid. II. Purification of toxoid by precipitation with acids.
Purification of Diphtheria Toxin and Toxoid made from Tryptic Digest Broths.
Purification of diphtheria toxin by chromatography on Cibacron Blue-Sepharose.
Purification of diphtheria toxin receptor from Vero cells.
Purification of diphtheria toxin. I. Application of zone electrophoresis in a starch-supporting medium as a means of fractionation of toxin.
Purification of diphtheria toxin. II. The isolation of crystalline toxin-protein and some of its properties.
Purification of elongation factor 2 from human placenta and evidence of its fragmentation patterns in various eukaryotic sources.
P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster.
Quantal entry of diphtheria toxin to the cytosol.
Quantification of diphtheria toxin mediated ADP-ribosylation in a solid-phase assay.
Quantitation of CRM197 using imaged capillary isoelectric focusing with fluorescence detection and capillary Western.
Quantitation of the Schmidt-Lanterman incisures in juvenile, adult, remyelinated and regenerated fibres of the chicken sciatic nerve.
Quantitative analysis of protein synthesis inhibition and recovery in CRM107 immunotoxin-treated HeLa cells.
Quantitative assessments of IgG and IgE antibodies to inhalant allergens in patients with atopic dermatitis.
QUANTITATIVE EXPERIMENTS WITH ANTIBODIES TO SPECIFIC PRECIPITATES. II.
Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death.
Quantitative restriction fragment length polymorphism: a procedure for quantitation of diphtheria toxin gene CRM197 allele.
Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer.
Raised soluble P-selectin moderately accelerates atherosclerotic plaque progression.
Raising at thermoneutrality prevents obesity and hyperphagia in BAT-ablated transgenic mice.
Random segretation of multiple genetic markers from CHO-CHO hybrids: evidence for random distribution of functional hemizygosity in the genome.
Rapamycin Corrects T Regulatory Cell Depletion and Improves Embryo Implantation and Live Birth Rates in a Murine Model.
Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line.
Rapid cellular removal of a membrane-inserted foreign polypeptide.
Rapid detection and molecular differentiation of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by LightCycler PCR.
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.
Rapid enzyme immunoassay for determination of toxigenicity among clinical isolates of corynebacteria.
Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.
Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity.
Rapid screening for toxigenic Corynebacterium diphtheriae by the polymerase chain reaction.
Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat.
Rational Design of Adjuvant for Skin Delivery: Conjugation of Synthetic ?-Glucan Dectin-1 Agonist to Protein Antigen.
Rationale for the use of immunotoxins in the treatment of HIV-infected humans.
Reaction of diphtheria toxin channels with sulfhydryl-specific reagents: observation of chemical reactions at the single molecule level.
Reaction of diphtheria toxin neuraminidase with human transferrin.
REACTIONS OF VALONIA AND OF HALICYSTIS TO COLLOIDS.
Reactivity of murine cytokine fusion toxin, diphtheria toxin390-murine interleukin-3 (DT390-mIL-3), with bone marrow progenitor cells.
Reasonable design of antibody mimetics for targeting glioma and small cell lung cancer.
Reassembled HVJ (Sendai virus) envelopes containing non-toxic mutant proteins of diphtheria toxin show toxicity to mouse L cell.
Rebooting the immune system with high-dose cyclophosphamide for treatment of refractory myasthenia gravis.
Recent advances in microbial toxin-related strategies to combat cancer.
Recent advances of animal model of focal segmental glomerulosclerosis.
Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy.
Recently identified nitrite-reactive compounds in food: occurrence and biological properties of the nitrosated products.
Receptor-based antidote for diphtheria.
Receptor-Directed Chimeric Toxins Created by Sortase-Mediated Protein Fusion.
Receptor-mediated endocytosis of diphtheria toxin by cells in culture.
Receptor-Mediated Enhanced Cellular Delivery of Nanoparticles Using Recombinant Receptor-Binding Domain of Diphtheria Toxin.
Receptor-mediated entry of diphtheria toxin into monkey kidney (Vero) cells: electron microscopic evaluation.
Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells.
Receptor-mediated transport of the hybrid protein ricin-diphtheria toxin fragment A with subsequent ADP-ribosylation of intracellular elongation factor II.
Receptor-mediated uptake of an extracellular Bcl-x(L) fusion protein inhibits apoptosis.
Receptor-targeted immunotherapy.
Recognition of elongation factor 2 by diphtheria toxin is not solely defined by the presence of diphthamide.
Recombinant baculovirus containing the diphtheria toxin A gene for malignant glioma therapy.
Recombinant Costimulatory Fusion Proteins as Functional Immunomodulators Enhance Antitumor Activity in Murine B16F10 Melanoma.
Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis.
Recombinant expression of Streptococcus pneumoniae capsular polysaccharides in Escherichia coli.
Recombinant fusion toxins--a new class of targeted biologic therapeutics.
Recombinant hybrid toxin with dual enzymatic activities. Potential use in preparing highly effective immunotoxins.
Recombinant immunoproapoptotic proteins with furin site can translocate and kill HER2-positive cancer cells.
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies.
Recombinant immunotoxins for the treatment of chemoresistant hematologic malignancies.
Recombinant immunotoxins for the treatment of haematological malignancies.
Recombinant immunotoxins for treating cancer.
Recombinant KRAS G12D Protein Vaccines Elicit Significant Anti-Tumor Effects in Mouse CT26 Tumor Models.
Recombinant modular transporters for cell-specific nuclear delivery of locally acting drugs enhance photosensitizer activity.
Recombinant receptor-binding domain of diphtheria toxin increases the potency of curcumin by enhancing cellular uptake.
Recombinant single-chain immunotoxins against T and B cell leukemias.
Recombinant Staphylococcus strains as live vectors for the induction of neutralizing anti-diphtheria toxin antisera.
Recombinant streptavidin-C3bot for delivery of proteins into macrophages.
Recombinant toxin DAB389EGF is cytotoxic to human pancreatic cancer cells.
Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.
Recombinant toxins for the treatment of cancer.
Recombinant toxins in haematologic malignancies and solid tumours.
Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria.
Reconstitution of diphtheria toxin from two nontoxic cross-reacting mutant proteins.
Reconstitution of Diphthine Synthase Activity in Vitro.
Reconstitution of fully active diphtheria toxin from purified fragments A and B.
Reconstitution of hybrid toxin from Fragment A of diphtheria toxin and a subunit of Wistaria floribunda lectin.
Reconstitution of lipid vesicles associated with HVJ (Sendai virus) sikes. Purification and some properties of vesicles containing nontoxic fragment A of diphtheria toxin.
Recovery from diabetes in mice by beta cell regeneration.
Recovery of function in Chinese hamster ovary cell mutants with temperature-sensitive defects in vacuolar acidification.
Reduced ribosomal binding of eukaryotic elongation factor 2 following ADP-ribosylation. Difference in binding selectivity between polyribosomes and reconstituted monoribosomes.
Reduction in circulating ghrelin concentration after maturation does not affect food intake.
Refined structure of dimeric diphtheria toxin at 2.0 A resolution.
Refined structure of monomeric diphtheria toxin at 2.3 A resolution.
Refining Protein Penetration into the Lipid Bilayer Using Fluorescence Quenching and Molecular Dynamics Simulations: The Case of Diphtheria Toxin Translocation Domain.
Regeneration in the Pituitary After Cell-Ablation Injury: Time-Related Aspects and Molecular Analysis.
Regenerative capacity of adult cortical thymic epithelial cells.
Regional assignment of the gene for diphtheria toxin sensitivity using subchromosomal fragments in microcell hybrids.
Regional mapping of human genes for hexosaminidase B and diphtheria toxin sensitivity on chromosome 5 using mouse X human hybrid cells.
Regression of extranodal natural killer/T-cell lymphoma, nasal type with denileukin diftitox (Ontak) and bexarotene (Targretin): report of a case.
Regression of prostate cancer xenografts by a lentiviral vector specifically expressing diphtheria toxin A.
Regulated expression of a diphtheria toxin A-chain gene transfected into human cells: possible strategy for inducing cancer cell suicide.
Regulated expression of diphtheria toxin in prostate cancer cells.
Regulated expression of the diphtheria toxin A chain by a tumor-specific chimeric transcription factor results in selective toxicity for alveolar rhabdomyosarcoma cells.
Regulated expression of the diphtheria toxin A gene in human glioma cells using prokaryotic transcriptional control elements.
Regulation of alcohol extinction and cue-induced reinstatement by specific projections between medial prefrontal cortex, nucleus accumbens and basolateral amygdala.
Regulation of CD8(+) T Cell Responses to Retinal Antigen by Local FoxP3(+) Regulatory T Cells.
Regulation of CD9 expression during 12-O-tetradecanoyl-phorbol-13-acetate- induced differentiation of human myeloid leukemia (HL-60) cells.
Regulation of cellular growth, apoptosis, and Akt activity in human U251 glioma cells by a combination of cisplatin with CRM197.
Regulation of expression of sodA and msrA genes of Corynebacterium glutamicum in response to oxidative and radiative stress.
Regulation of insulin-like growth factor (IGF) binding proteins in transgenic mice with altered expression of growth hormone and IGF-I.
Regulation of lymphatic function and injury by nitrosative stress in obese mice.
Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function.
REGULATORY MECHANISM OF THE SYNTHESIS OF DIPHTHERIA TOXIN IN THE CELL-FREE SYSTEM. INHIBITORY FACTORS IN CELLS GROWN IN THE MEDIUM WITH EXCESS OF IRON.
Regulatory mechanisms of the formation of diphtheria toxin. I. Isolation and property of an inhibitory factor.
Regulatory mechanisms of the formation of diphtheria toxin. II. Mode of action of an inhibitory substance on the toxin formation in a cell-free system.
Regulatory T cell transfer ameliorates lymphedema and promotes lymphatic vessel function.
Regulatory T cells control endothelial chemokine production and migration of T cells into intestinal tumors of APCmin/+ mice.
Regulatory T cells control epitope spreading in autoimmune arthritis independent of cytotoxic T-lymphocyte antigen-4.
Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.
Regulatory T cells in B-cell-deficient and wild-type mice differ functionally and in expression of cell surface markers.
Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium.
Regulatory T cells specifically suppress conventional CD8?? T cells in intestinal tumors of APCMin/+ mice.
Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
Relation of the Index of Alkalinity to the Production of Diphtheria Toxin.
Reliable differentiation of a non-toxigenic tox gene-bearing Corynebacterium ulcerans variant frequently isolated from game animals using MALDI-TOF MS.
Remyelination by cells introduced into a stable demyelinating lesion in the central nervous system.
Remyelination in the central diphtheria toxin lesion.
Remyelination in the chicken sciatic nerve.
Renal Dendritic Cells Ameliorate Nephrotoxic Acute Kidney Injury.
Renal dendritic cells stimulate IL-10 production and attenuate nephrotoxic nephritis.
Renal dysfunction accounts for the dose limiting toxicity of DT390anti-CD3sFv, a potential new recombinant anti-GVHD immunotoxin.
Rendering a membrane protein soluble in water: a common packing motif in bacterial protein toxins.
Renin cells with defective Gs?/cAMP signaling contribute to renal endothelial damage.
Reoxygenation of hypoxic glioblastoma multiforme cells potentiates the killing effect of an interleukin-13-based cytotoxin.
Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain.
Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels.
Replacing the in vivo toxin challenge test with an in vitro assay for assessment of potency for diphtheria toxoid containing vaccines.
Reproducible production of protective human monoclonal antibodies by fusion of peripheral blood lymphocytes with a mouse myeloma cell line.
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin.
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH.
Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus.
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane.
Requirements for the translocation of diphtheria toxin fragment A across lipid membranes.
Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis.
Resident pleural macrophages are key orchestrators of neutrophil recruitment in pleural inflammation.
Resimmune, an anti-CD3? recombinant immunotoxin, induces durable remissions in patients with cutaneous T-cell lymphoma.
Resistance against ricin-induced apoptosis in a brefeldin A-resistant mutant cell line (BER-40) of Vero cells.
Respiratory illness caused by Corynebacterium diphtheriae and C. ulcerans, and use of diphtheria anti-toxin in the United States, 1996-2018.
Response of cultured mammalian cells to diphtheria toxin. 3. Inhibition of protein synthesis studied at the subcellular level.
Response of cultured mammalian cells to diphtheria toxin. IV. Isolation of KB cells resistant to diphtheria toxin.
Response of cultured mammalian cells to diphtheria toxin. V. Concurrent resistance to ribonucleic acid viruses in diphtheria toxin-resistant KB cell strains.
Response of interferon-treated cells to diphtheria toxin.
Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis.
Response of recent human immunodeficiency virus seroconverters to the pneumococcal polysaccharide vaccine and Haemophilus influenzae type b conjugate vaccine.
Response to a Haemophilus influenzae type b diphtheria CRM197 conjugate vaccine in children with a defect of antibody production to Haemophilus influenzae type b polysaccharide.
Responses of cell cultures to insecticides. 3. Altered susceptibility to poliovirus and diphtheria toxin.
Resurgence of diphtheria in rural areas of North Karnataka, India.
Retinal degeneration in cone photoreceptor cell-ablated transgenic mice.
Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice.
Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice.
Retinal microangiopathy in a mouse model of inducible mural cell loss.
Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene.
Retroviral immunotoxin gene therapy of leukemia in mice using leukemia-specific T cells transduced with an interleukin-3/Bax fusion protein gene.
Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins.
Reversed passive latex agglutination assay for detection of toxigenic Corynebacterium diphtheriae.
Reversible increase in the saturation of C18 fatty acids induced by diphtheria toxin in tissue culture cells.
Reversible refolding of the diphtheria toxin T-domain on lipid membranes.
Reversion of recombinant toxoids: mutations in diphtheria toxin that partially compensate for active-site deletions.
Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins.
Rhinovirus Infection Induces IL-13 Production from CD11b-positive, Exudative M2-polarized Exudative Macrophages.
Ribosome-bound elongation factor 2 escapes phosphorylation by Ca2+/calmodulin-dependent protein kinase III.
Ribosomes terminated in vitro are in a tight association with non-phosphorylated elongation factor 2 (eEF-2) and GDP.
Ribosyl-diphthamide: confirmation of structure by fast atom bombardment mass spectrometry.
Ribozyme-mediated selective induction of new gene activity in hepatitis C virus internal ribosome entry site-expressing cells by targeted trans-splicing.
Ricin cytotoxicity is sensitive to recycling between the endoplasmic reticulum and the Golgi complex.
Ricin linked to monophosphopentamannose binds to fibroblast lysosomal hydrolase receptors, resulting in a cell-type-specific toxin.
Ricin-mediated cell-lysis and apoptosis of drug sensitive and resistant tumor-cells.
Rod and cone function in coneless mice.
Rodent models of AKI-CKD transition.
Role of acidic residues in helices TH8-TH9 in membrane interactions of the diphtheria toxin T domain.
Role of agouti-related protein-expressing neurons in lactation.
Role of anions in low pH-induced translocation of diphtheria toxin.
Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis.
Role of caspases in immunotoxin-induced apoptosis of cancer cells.
Role of CypA and Hsp90 in membrane translocation mediated by anthrax Protective Antigen.
Role of dendritic cells in enhancement of herpes simplex virus type 1 latency and reactivation in vaccinated mice.
Role of denileukin diftitox in the treatment of persistent or recurrent cutaneous T-cell lymphoma.
Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells.
Role of glycosylation in expression of functional diphtheria toxin receptors.
Role of Glycosylation in Expression of Functional Diphtheria Toxin Receptors.
Role of Lgr5-positive cells in colorectal cancer.
Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness.
Role of neuropeptide Y in diet-, chemical- and genetic-induced obesity of mice.
Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome.
Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson's disease.
Role of the 5.8S rRNA in ribosome translocation.
Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin.
Route of pseudomonas and diphtheria toxin entry into mammalian cells: basis for susceptibility to toxin.
Saccharomyces cerevisiae elongation factor 2. Genetic cloning, characterization of expression, and G-domain modeling.
Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin.
Saccharomyces cerevisiae spheroplasts are sensitive to the action of diphtheria toxin.
Safe and Efficacious Diphtheria Toxin-Based Treatment for Melanoma: Combination of a Light-On Gene-Expression System and Nanotechnology.
Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Safety and immunogenicity of a nonavalent pneumococcal vaccine conjugated to CRM197 administered simultaneously but in a separate syringe with diphtheria, tetanus and pertussis vaccines in Gambian infants.
Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine in Healthy Meningococcal-Naïve Children 2-9 Years of Age: A Phase III, Randomized Study.
Safety and immunogenicity of Haemophilus influenzae type b oligosaccharide-CRM197 conjugate vaccine in infants aged 15 to 23 months.
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers.
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants.
Safety and immunogenicity of PRP-T combined with DTP: excretion of capsular polysaccharide and antibody response in the immediate post-vaccination period.
Safety and immunogenicity of Shigella sonnei-CRM9 and Shigella flexneri type 2a-rEPAsucc conjugate vaccines in one- to four-year-old children.
Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey.
Safety, tolerability, and immunogenicity of a single dose 4-antigen or 3-antigen Staphylococcus aureus vaccine in healthy older adults: Results of a randomised trial.
Safety, tolerability, and immunogenicity of concurrent administration of Haemophilus influenzae type b conjugate vaccine (meningococcal protein conjugate) with either measles-mumps-rubella vaccine or diphtheria-tetanus-pertussis and oral poliovirus vaccines in 14- to 23-month-old infants.
Sandwich-dot immunobinding assay (Sandwich-DIA), a new immunological method for the detection of diphtheria toxin.
Scar Formation and Debris Elimination during Hair Cell Degeneration in the Adult DTR Mouse.
Schick test reaction, serum antitoxin titre and resistance to lethal doses of diphtheria toxin in guinea pigs.
Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1.
Screening tests for pathogenic corynebacteria.
Seamless Genome Editing in Rice via Gene Targeting and Precise Marker Elimination.
Second cytotoxic pathway of diphtheria toxin suggested by nuclease activity.
Secondary structure changes of diphtheria toxin interacting with asolectin liposomes: an infrared spectroscopy study.
Secondary structure of diphtheria toxin and its fragments interacting with acidic liposomes studied by polarized infrared spectroscopy.
Secretory expression of recombinant diphtheria toxin mutants in B. Subtilis.
Selection and characterization of cells resistant to diphtheria toxin and pseudomonas exotoxin A: presumptive translational mutants.
Selection of diphtheria toxin active-site mutants in yeast. Rediscovery of glutamic acid-148 as a key residue.
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.
Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model.
Selective ablation of inner hair cells and subsequent in-situ hair cell regeneration in the neonatal mouse cochlea.
Selective ablation of pillar and deiters' cells severely affects cochlear postnatal development and hearing in mice.
Selective activation of antigen-specific human B cells in recently immunized individuals by nonspecific factors in the absence of antigen.
Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice.
Selective antibody deficiency to Haemophilus influenzae type B capsular polysaccharide vaccination in children with recurrent respiratory tract infection.
Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons.
Selective depletion of Foxp3(+) Treg during sensitization phase aggravates experimental allergic airway inflammation.
Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma.
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.
Selective depletion of mouse kidney proximal straight tubule cells causes acute kidney injury.
Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells.
Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133.
Selective elimination of HIV-1-infected cells with an interleukin-2 receptor-specific cytotoxin.
Selective hair cell ablation and noise exposure lead to different patterns of changes in the cochlea and the cochlear nucleus.
Selective inhibition of hepatoma cells using diphtheria toxin A under the control of the promoter/enhancer region of the human alpha-fetoprotein gene.
Selective killing of human immunodeficiency virus-infected and -producing cells by liposomes containing diphtheria toxin fragment A.
Selective killing of RPE with a vascular endothelial growth factor chimeric toxin.
Selective killing of subacute sclerosing panencephalitis virus-infected cells by liposomes containing fragment A of diphtheria toxin.
Selective killing of T cells by immunotoxins directed at distinct V beta epitopes of the T cell receptor.
Selective primary health care: strategies for control of disease in the developing world. XVII. Pertussis and diphtheria.
Selective toxicity of diphtheria toxin for malignant cells.
Selective translocation of the A chain of diphtheria toxin across the membrane of purified endosomes.
Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs.
Self-translocation of diphtheria toxin across model membranes.
Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells Articlefrom Intoxication.
Sensitivity of cancer cells to truncated diphtheria toxin.
Sensitivity to diphtheria toxin as a species-specific marker in hybrid cells.
Separation of diphtheria toxin proteins by Sephadex gel.
Sequence analysis of the peptide-elongation factor EF-2 gene, downstream from those of ribosomal proteins H-S12 and H-S7, from the archaebacterial extreme halophile, Halobacterium halobium.
Sequence and structural links between distant ADP-ribosyltransferase families.
Sequence of ligand binding and structure change in the diphtheria toxin repressor upon activation by divalent transition metals.
Seroepidemiology of diphtheria and pertussis in Chongqing, China: serology-based evidence of Bordetella pertussis infection.
Serological evaluation of a simplified immunization schedule using quadruple DPT-polio vaccine in Burkina Faso.
Serological immunity to diphtheria in Sweden in 1978 and 1984.
Seroprevalence and Determinants of Immunity to Diphtheria for Children Living in Two Districts of Contrasting Incidence During an Outbreak in East Java, Indonesia.
Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis.
Seroprevalence of diphtheria toxoid IgG antibodies in children, adolescents and adults in Poland.
Sertoli cell replacement in explanted mouse testis tissue supporting host spermatogenesis.
Sertoli cells maintain Leydig cell number and peritubular myoid cell activity in the adult mouse testis.
Serum antibodies to the components of diphtheria-tetanus-pertussis vaccine in Polish children related to vaccination status.
Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune Diseases.
Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations.
Severe Pneumonia Caused by Toxigenic Corynebacterium ulcerans Infection, Japan.
Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis.
Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leucocytes through a common receptor.
Side chain resonances in static oriented proton-decoupled 15N solid-state NMR spectra of membrane proteins.
SiglecH(+) plasmacytoid dendritic cells drive spontaneous lupus-like disease development in B6.Nba2 mice.
Similarity of the conformation of diphtheria toxin at high temperature to that in the membrane-penetrating low-pH state.
Simultaneous Evaluation of a Vaccine Component Microheterogeneity and Conformational Integrity Using Native Mass Spectrometry and Limited Charge Reduction.
Simultaneous multicolor detection system of the single-molecular microbial antigen with total internal reflection fluorescence microscopy.
Single mutation in the A domain of diphtheria toxin results in a protein with altered membrane insertion behavior.
Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
SirR, a novel iron-dependent repressor in Staphylococcus epidermidis.
Site in cell-free protein synthesis sensitive to diphtheria toxin.
Site-directed spin labeling of proteins. Applications to diphtheria toxin.
Site-specific mutagenesis of the histidine precursor of diphthamide in the human elongation factor-2 gene confers resistance to diphtheria toxin.
Skin changes in rabbits' ears produced by repeated intracutaneous injections of diphtheria toxin.
SL-401 and SL-501, targeted therapeutics directed at the interleukin-3 receptor, inhibit the growth of leukaemic cells and stem cells in advanced phase chronic myeloid leukaemia.
Sleep and Wakefulness Are Controlled by Ventral Medial Midbrain/Pons GABAergic Neurons in Mice.
Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis.
Sodium channel distribution in axons of hypomyelinated and MAG null mutant mice.
Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain.
Solution stability studies of the subunit components of meningococcal C oligosaccharide-CRM197 conjugate vaccines.
Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein.
Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Somatic cell genetics of human interferon production in human-rodent cell hybrids.
Somatic cell mutants resistant to ricin, diphtheria toxin, and to immunotoxins.
Some cardiovascular and fluid change effects of intravenously administered diphtheria toxin in dogs.
Some new observations on diphtheria toxin and antitoxin.
Some observations on the effects of diphtheria toxin on embryonated eggs and on tissue culture and their use for toxin titrations.
Some peripheral actions of diphtheria toxin.
Some physiological mechanisms of diphtheria toxin production.
Some properties of IgG against diphtheria toxin synthesized in Xenopus oocytes containing mRNA from hybridoma.
Some properties of the diphtheria toxin fragment produced by a beta phage-mutant lysogen of Corynebacterium diphtheriae.
Some unusual manifestations of proteolysis.
SOX14 IS REQUIRED FOR A SPECIFiC SUBSET OF CEREBELLO-OLIVARY PROJECTIONS.
Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy.
Specific antibodies to diphtheria toxin and type 6A pneumococcal capsular polysaccharide induced by a model of semi-synthetic glycoconjugate antigen.
Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence.
Specific chemical cleavage of diphtheria toxin with hydroxylamine. Purification and characterization of the modified proteins.
Specific cleavage of diphtheria toxin by human urokinase.
Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage.
Specific disruption of vimentin filament organization in monkey kidney CV-1 cells by diphtheria toxin, exotoxin A, and cycloheximide.
Specific efflux of glutathione from the basolateral membrane domain in polarized MDCK cells during ricin-induced apoptosis.
Specific immune responses and enhancement of murine pulmonary clearance of Moraxella catarrhalis by intranasal immunization with a detoxified lipooligosaccharide conjugate vaccine.
Specific permeability properties of demyelinated rat nerve fibres.
Specific purification of elongation factor 2 and isolation of its antibody.
Specific reversal of diphtheria toxin mediated inhibition of protein synthesis in guinea pig tissues.
Specific targeting of tumor vasculature by diphtheria toxin-vascular endothelial growth factor fusion protein reduces angiogenesis and growth of pancreatic cancer.
Specificity of Diphtheria Toxin Action on Heart and Muscle Tissues of Guinea Pigs.
Standardization and validation of Vero cell assay for potency estimation of diphtheria antitoxin serum.
Status of paratyphoid fever vaccine research and development.
Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells.
Stealth and mimicry by deadly bacterial toxins.
Stimulation of activin receptor II signaling pathways inhibits differentiation of multiple gastric epithelial lineages.
Stimulation of CD8+ T cells following diphtheria toxin-mediated antigen delivery into dendritic cells.
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization.
Strain-dependent arthritogenic potential of the zoonotic pathogen Corynebacterium ulcerans.
Strains of CHO-K1 cells resistant to Pseudomonas exotoxin A and cross-resistant to diphtheria toxin and viruses.
Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice.
Striatal cholinergic cell ablation attenuates L-DOPA induced dyskinesia in Parkinsonian mice.
Structural analysis and insight into metal-ion activation of the iron-dependent regulator from Thermoplasma acidophilum.
Structural analysis of the manganese transport regulator MntR from Bacillus halodurans in apo and manganese bound forms.
Structural and antigenic features of the synthetic SF23 peptide corresponding to the receptor binding fragment of diphtheria toxin.
Structural and functional comparisons of pH-sensitive liposomes composed of phosphatidylethanolamine and three different diacylsuccinylglycerols.
Structural and functional hemi- and dizygous Chinese hamster chromosome 2 gene loci in CHO cells.
Structural and immunological characterization of E. coli derived recombinant CRM197 protein used as carrier in conjugate vaccines.
Structural Basis for Lack of ADP-Ribosyltransferase Activity in Poly(ADP-Ribose) Polymerase-13/Zinc Finger Antiviral Protein.
Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197.
Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.
Structural gene of diphtheria toxin.
Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor.
Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments.
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule.
Structure and expression of elongation factor 2 gene during development of Dictyostelium discoideum.
Structure and interaction with model membranes of a CNBR peptide of diphtheria toxin B fragment.
Structure and topology of diphtheria toxin R domain in lipid membranes.
Structure function relationships in diphtheria toxin channels: II. A residue responsible for the channel's dependence on trans pH.
Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain.
Structure of the isolated catalytic domain of diphtheria toxin.
Structure of the manganese-bound manganese transport regulator of Bacillus subtilis.
Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex.
Structure of the N-terminal region of Haemophilus influenzae H10017: implications for function.
Structure-activity relationships in diphtheria toxin and exotoxin A from Pseudomonas aeruginosa.
Structure-activity relationships in diphtheria toxin and Pseudomonas aeruginosa exotoxin A.
Structure-activity relationships in diphtheria toxin.
Structure-activity relationships of the B fragment of diphtheria toxin: the lipid-binding domains.
Structure-function analyses of diphtheria toxin by use of monoclonal antibodies.
Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis.
Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa.
Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes.
Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain.
Structure-function relationships in diphtheria toxin channels: III. Residues which affect the cis pH dependence of channel conductance.
Structure-guided design of a Group B Streptococcus type III synthetic glycan-conjugate vaccine.
Structure/function analysis of interleukin-2-toxin (DAB486-IL-2). Fragment B sequences required for the delivery of fragment A to the cytosol of target cells.
Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells.
Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae.
Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Structures of two archaeal diphthine synthases: insights into the post-translational modification of elongation factor 2.
Structures, Properties, and Dynamics of Intermediates in eEF2-Diphthamide Biosynthesis.
Studies in Diphtheria Toxin Production. I: The Effect of Iron and Copper.
Studies in Diphtheria Toxin Production. II: Production of Potent Diphtheria Toxin on a Simple Amino-Acid Medium.
Studies in Diphtheria Toxin Production. III: A Simple Gelatin Hydrolysate Medium and Some Properties of the Toxin Produced thereon.
STUDIES IN GLOMERULONEPHRITIS : I. A QUANTITATIVE STUDY OF THE REACTION OF THE KIDNEY TO DIPHTHERIA TOXIN.
STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
Studies of the activity of diphtheria toxin. I. Poliovirus replication in intoxicated HeLa cells.
Studies of the diphtheria toxin receptor on Chinese hamster cells.
Studies of the mechanism of cell intoxication by diphtheria toxin fragment A-asialoorosomucoid hybrid toxins. Evidence for utilization of an alternative receptor-mediated transport pathway.
STUDIES ON CARBON DIOXIDE V. THE MECHANISM RESPONSIBLE FOR THE PRESERVING ACTION OF CARBON DIOXIDE ON DIPHTHERIA TOXIN.
Studies on changes associated with conversion of diphtheria toxin into diphtheria toxoid with formalin and heat.
Studies on Diphtheria Toxin : II. The Rôle of the Amino Acids in the Metabolism of Bacterium diphtheriae.
Studies on Diphtheria Toxin and Its Reaction with Antitoxin.
Studies on diphtheria toxin. Interaction with structural protein of mitochondria.
Studies on diphtheria toxin. The effect of GTP on the toxin-dependent adenosine diphosphate ribosylation of rat liver aminoacyl transferase. II.
Studies on peroxidative detoxification of purified diphtheria toxin.
Studies on the conditions for diphtheria toxin production. 1. Influences of the NaCl and Fe content of the culture medium on the pattern of toxin production.
Studies on the cultivation of micro-organisms on a semi-industrial scale. III. Plastic coatings as an aid in the production of diphtheria toxin in metal tanks.
Studies on the decomposition of diphtheria toxin by soil bacteria.
Studies on the detoxification of purified diphtheria toxin.
Studies on the effect of diphtheria toxin on protein synthesis in mice.
Studies on the mechanisms of toxin production of C diphtheria. II. On the relation between protein substance made by non-toxigenic strains of C. diphtheriae and diphtheria toxin.
Studies on the mode of action of diphtheria toxin. 3. Site of toxin action in cell-free extracts.
STUDIES ON THE MODE OF ACTION OF DIPHTHERIA TOXIN. I. PHOSPHORYLATED INTERMEDIATES IN NORMAL AND INTOXICATED HELA CELLS.
Studies on the mode of action of diphtheria toxin. I. Protein synthesis in guinea pig tissues.
STUDIES ON THE MODE OF ACTION OF DIPHTHERIA TOXIN. II. EFFECT OF TOXIN ON AMINO ACID INCORPORATION IN CELL-FREE SYSTEMS.
Studies on the mode of action of diphtheria toxin. II. Protein synthesis in primary heart cell cultures.
Studies on the mode of action of diphtheria toxin. III. Effect on subcellular components of protein synthesis from the tissues of intoxicated guinea pigs and rats.
Studies on the mode of action of diphtheria toxin. IV. Specificity of the cofactor (NAD) requirement for toxin action in cell-free systems.
Studies on the mode of action of diphtheria toxin. Protein synthesis in guinea pig tissues and primary heart cell cultures.
Studies on the mode of action of diphtheria toxin. V. Inhibition of peptide bond formation by toxin and NAD in cell-free systems and its reversal by nicotinamide.
Studies on the mode of action of diphtheria toxin. V. Protein metabolism in a guinea pig model simulating chronic diphtheritic toxemia.
Studies on the mode of action of diphtheria toxin. VI. Inhibition of protein synthesis induced by local infection with toxingenic Corynebacterium diphtheriae.
Studies on the mode of action of diphtheria toxin. VI. Site of the action of toxin in living cells.
Studies on the mode of action of diphtheria toxin. VII. Toxin-stimulated hydrolysis of nicotinamide adenine dinucleotide in mammalian cell extracts.
STUDIES ON THE MOLECULAR WEIGHT OF DIPHTHERIA TOXIN, ANTITOXIN, AND THEIR REACTION PRODUCTS.
Studies on the purification of diphtheria toxin.
Studies on the role of a nucleoside-phosphate-binding site of diphtheria toxin in the binding of toxin to Vero cells or liposomes.
STUDIES ON THE SHWARTZMAN PHENOMENON : I. DETOXIFICATION OF MENINGOCOCCUS CULTURE FILTRATES.
Studies on the toxin-anaphylaxis and the rate of combination of diphtheria toxin and antitoxin in vitro.
Studies on transferase II using diphtheria toxin.
Study of localization of the protein-synthesizing machinery along actin filament bundles.
Study on the use of an enzyme-linked immunosorbent assay in determining human antibodies to diphtheria toxin as compared with a reference toxin neutralization assay.
Study on the variables affecting toxicity of hybrid toxins. The effect of different target cell receptor distribution and toxin binding chain.
Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice.
Subcapsular sinus macrophages limit acute gammaherpesvirus dissemination.
Subcloning and characterization of the binding domain of fragment B of diphtheria toxin.
Successful immunization with a totally synthetic diphtheria vaccine.
Successful induction of protective antibody responses against Haemophilus influenzae type b and diphtheria after transcutaneous immunization with the glycoconjugate polyribosyl ribitol phosphate-cross-reacting material 197 vaccine.
Suitability of the Vero cell method for titration of diphtheria antitoxin in the United States potency test for diphtheria toxoid.
Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro.
Suppression of Cytotoxicity of Diphtheria Toxin by Monoclonal Antibodies Against Phosphatidylinositol Phosphate.
Suppression of immune responses to acetylcholine receptor by interleukin 2-fusion toxin: in vivo and in vitro studies.
Suppression of in vitro IgM rheumatoid factor production by diphtheria toxin interleukin 2 recombinant fusion protein (DAB 486IL-2) in patients with refractory rheumatoid arthritis.
Suppression of lens growth by alphaA-crystallin promoter-driven expression of diphtheria toxin results in disruption of retinal cell organization in zebrafish.
Suppression of single and double nonsense mutations introduced into the diphtheria toxin A-chain gene: a potential binary system for toxin gene therapy.
Suppression of the biological activities of the epidermal growth factor (EGF)-like domain by the heparin-binding domain of heparin-binding EGF-like Growth Factor.
Suppression of the immune response to immunotoxins with anti-CD4 monoclonal antibodies.
Suppressive effect of liposomes containing DNA coding for diphtheria toxin A-chain on cells transformed with bovine leukemia virus.
Surface plasmon resonance analysis of antipolysaccharide antibody specificity: responses to meningococcal group C conjugate vaccines and bacteria.
Susceptibility to diphtheria in adults: prevalence and relationship to gender and social variables.
Sustained in vivo depletion of splenic langerin(+) CD8?(+) dendritic cells is well-tolerated by lang-DTREGFP mice.
Sustained root culture for generation and vegetative propagation of transgenic Arabidopsis thaliana.
Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines.
Synthesis and characterization of lipooligosaccharide-based conjugate vaccines for serotype B Moraxella catarrhalis.
Synthesis and cytotoxic profile of a diphtheria toxin-neurotrophin-4 chimera.
Synthesis and Evaluation of Glycoconjugates Comprising N-Acyl-Modified Thomsen-Friedenreich Antigens as Anticancer Vaccines.
Synthesis and in vitro activity of a hormone-diphtheria toxin fragment A hybrid.
Synthesis and vaccine evaluation of the tumor-associated carbohydrate antigen RM2 from prostate cancer.
Synthesis of a cytotoxic insulin cross-linked to diphtheria toxin fragment A capable of recognizing insulin receptors.
SYNTHESIS OF DIPHTHERIA TOXIN IN A CELL-FREE SYSTEM.
Synthesis of diphtheria toxin in E. coli cell-free lysate.
Synthesis of Streptococcus pneumoniae type 3 neoglycoproteins varying in oligosaccharide chain length, loading and carrier protein.
Synthesis, characterization, and immunogenicity in mice of Shigella sonnei O-specific oligosaccharide-core-protein conjugates.
Synthesis, cytotoxic properties and effects on early and late gene induction of a chimeric diphtheria toxin-leukemia-inhibitory factor protein.
Synthesizing a Genetic Sensor Based on CRISPR-Cas9 for Specifically Killing p53-Deficient Cancer Cells.
Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light.
Synthetic oligosaccharides as tools to demonstrate cross-reactivity between polysaccharide antigens.
Synthetic peptide representing a T-cell epitope of CRM197 substitutes as carrier molecule in a Haemophilus influenzae type B (Hib) conjugate vaccine.
Synthetic polysaccharide type 3-related di-, tri-, and tetrasaccharide-CRM(197) conjugates induce protection against Streptococcus pneumoniae type 3 in mice.
Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys.
T cell-dependent protective effects of CpG motifs of bacterial DNA in experimental colitis are mediated by CD11c+ dendritic cells.
Tagraxofusp and anti-CD123 in blastic plasmacytoid dendritic cell neoplasm: a new hope.
Tagraxofusp as treatment for patients with blastic plasmacytoid dendritic cell neoplasm.
Tagraxofusp for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): A Brief Report on Emerging Data.
Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm.
Tagraxofusp, a novel CD123-directed cytotoxin to treat blastic plasmacytoid dendritic cell neoplasm.
Tagraxofusp, the first CD123-targeted therapy and first targeted treatment for blastic plasmacytoid dendritic cell neoplasm.
Tagraxofusp: First Global Approval.
Tangential flow filtration technology applicable to large scale recovery of diphtheria toxin.
Target-cell specificity of fusogenic liposomes: membrane fusion-mediated macromolecule delivery into human blood mononuclear cells.
Targeted ablation of alpha-crystallin-synthesizing cells produces lens-deficient eyes in transgenic mice.
Targeted ablation of cells in the pituitary primordia of transgenic mice.
Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet.
Targeted ablation of gonadotrophs in transgenic mice affects embryonic development of lactotrophs.
Targeted ablation of gonadotrophs in transgenic mice depresses prolactin but not growth hormone gene expression at birth as measured by quantitative mRNA detection.
Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination.
Targeted ablation of oligodendrocytes triggers axonal damage.
Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction.
Targeted ablation of pituitary gonadotropes in transgenic mice.
Targeted Apoptosis of Parietal Cells Is Insufficient to Induce Metaplasia in Stomach.
Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma.
Targeted delivery across the blood-brain barrier.
Targeted delivery of diphtheria toxin via immunoliposomes: efficient antitumor activity in the presence of inactivating anti-diphtheria toxin antibodies.
Targeted depletion of monocyte/macrophage suppresses aortic dissection with the spatial regulation of MMP-9 in the aorta.
Targeted diphtheria toxin to treat BPDCN.
Targeted Diphtheria Toxin-Based Therapy: A Review Article.
Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity.
Targeted expression of a toxin gene to D1 dopamine receptor neurons by cre-mediated site-specific recombination.
Targeted Injury of Type II Alveolar Epithelial Cells Induces Pulmonary Fibrosis.
Targeted Interneuron Ablation in the Mouse Hippocampus Can Cause Spontaneous Recurrent Seizures.
Targeted introduction of a diphtheria toxin resistant mutation into the chromosomal EF-2 locus of Pichia pastoris and expression of immunotoxin in the EF-2 mutants.
Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells.
Targeted neuronal cell ablation in the Drosophila embryo: pathfinding by follower growth cones in the absence of pioneers.
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis.
Targeted therapy of acute myeloid leukemia with monoclonal antibodies and immunoconjugates.
Targeted therapy to the IL-2R using diphtheria toxin and caspase-3 fusion proteins modulates Treg and ameliorates inflammatory colitis.
Targeted toxin therapy for the treatment of cancer.
Targeted tumor therapies at a glance.
Targeting and eradicating cancer cells by a prostate-specific vector carrying the diphtheria toxin A gene.
Targeting Bone Cells During Sexual Maturation Reveals Sexually Dimorphic Regulation of Endochondral Ossification.
Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins.
Targeting cancer cells by novel engineered modular transporters.
Targeting diphtheria toxin A-chain transcription to activated endothelial cells using an E-selectin promoter.
Targeting diphtheria toxin and TNF alpha expression in ovarian tumors using the H19 regulatory sequences.
Targeting diphtheria toxin to growth factor receptors.
Targeting electrostatic interactions in accelerated molecular dynamics with application to protein partial unfolding.
Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice.
Targeting head and neck squamous cell carcinoma using a novel fusion toxin-diphtheria toxin/HN-1.
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.
Targeting indirect pathway CD4 T-cell alloresponses in the prevention of chronic transplant rejection.
Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: ex vivo and in vivo studies in mice.
Targeting of specific domains of diphtheria toxin by site-directed antibodies.
Targeting solid tumors via T cell receptor complementarity-determining region 3delta in an engineered antibody.
Targeting the EGF receptor in breast cancer treatment.
Targeting the Epidermal Growth Factor Receptor in Breast Cancer Cell Lines With a Recombinant Ligand Fusion Toxin (DAB389EGF)
Targeting the over-expressed urokinase-type plasminogen activator receptor on glioblastoma multiforme.
Targeting the tumor vasculature: inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate.
Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT.
Technical advance: an aniline blue staining procedure for confocal microscopy and 3D imaging of normal and perturbed cellular phenotypes in mature Arabidopsis embryos.
Technology evaluation: TransMID, KS Biomedix/Nycomed/Sosei/PharmaEngine.
Temperature sensitive diphtheria toxin confers conditional male-sterility in Arabidopsis thaliana.
Temperature-dependent feeding: lack of role for leptin and defect in brown adipose tissue-ablated obese mice.
Temporal separation of protein toxin translocation from processing events.
Testicular Cell Selective Ablation Using Diphtheria Toxin Receptor Transgenic Mice.
Testing for neutralising potential of serum antibodies to tetanus and diphtheria toxin.
Tetanus neurotoxin utilizes two sequential membrane interactions for channel formation.
Tetanus toxin fragment forms channels in lipid vesicles at low pH.
Tetanus toxin induces fusion and aggregation of lipid vesicles containing phosphatidylinositol at low pH.
Tetracel (American Home Products).
Tetracycline-controlled expression but not toxicity of an attenuated diphtheria toxin mutant.
Th1-directing adjuvants increase the immunogenicity of oligosaccharide-protein conjugate vaccines related to Streptococcus pneumoniae type 3.
The 100-kDa protein, whose phosphorylation precedes the fusion of chick embryonic myoblasts, is the eukaryotic elongation factor-2.
The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells.
The Action of Diphtheria Toxin on Mice.
The action of diphtheria toxin on tissue cultures and its neutralization by antitoxin.
THE ACTION OF DIPHTHERIA TOXIN ON TISSUE CULTURES OF EMBRYONIC GUINEA PIG CELLS. II.
The action of pepsin on protein fractions from horse antisera to diphtheria toxin.
The adjuvant effect of synthetic oligodeoxynucleotide containing CpG motif converts the anti-Haemophilus influenzae type b glycoconjugates into efficient anti-polysaccharide and anti-carrier polyvalent vaccines.
The adult pituitary shows stem/progenitor cell activation in response to injury and is capable of regeneration.
The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network.
The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. I. The tryptic peptides from the maleylated protein.
The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. II. The cyanogen bromide peptides.
The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. III. The chymotryptic peptides, the peptides derived by cleavage at tryptophan residues, and the complete sequence of the protein.
The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197.
The Antigenic Properties of Precipitates Produced by the Interaction of Diphtheria Toxin and Antitoxin.
The Antigenic Properties of Precipitates Produced by the Interaction of Diphtheria Toxin and Antitoxin.—Part 2.
The application of paper partition chromatography to the production of diphtheria toxin.
The application of paper partition chromatography to the production of diphtheria toxin; two-dimensional chromatography.
The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases.
The assay of diphtheria toxin using mouse.
The assay of diphtheria toxin.
The association between tuberculosis and diphtheria.
The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis.
The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout.
The Basoph8 Mice Enable an Unbiased Detection and a Conditional Depletion of Basophils.
The binding of tritiated elongation-factors 1 and 2 to ribosomes from Krebs II mouse ascites-tumore cells. The influence of various antibiotics and toxins.
The biosynthesis and biological function of diphthamide.
The cell and molecular basis of mechanical, cold, and inflammatory pain.
The complete amino acid sequence of diphtheria toxin fragment B. Correlation with its lipid-binding properties.
The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.
The complete nucleotide sequence of the gene coding for diphtheria toxin in the corynephage omega (tox+) genome.
The Complexity of Diphtheria Toxin.
The conjugation of diphtheria toxin T domain to poly(ethylenimine) based vectors for enhanced endosomal escape during gene transfection.
The core clock transcription factor BMAL1 drives circadian ?-cell proliferation during compensatory regeneration of the endocrine pancreas.
The crystal structure of diphtheria toxin.
The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin.
The cytoplasmic domain of the diphtheria toxin receptor (HB-EGF precursor) is not required for receptor-mediated endocytosis.
The cytosolic domain of Bcl-2 oligomerizes to form pores in model mitochondrial outer membrane at acidic pH.
The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex.
The cytotoxic action of diphtheria toxin and its degradation in intact Vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase.
The cytotoxic effect of diphtheria toxin on the actin cytoskeleton.
The Degree and Duration of Passive Immunity to Diphtheria Toxin transmitted by immunized Female Guinea-Pigs to their immediate offspring.
The delta-endotoxin protein family displays a hydrophobic motif that might be implicated in toxicity.
The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells.
THE DESTRUCTION OF DIPHTHERIA TOXIN BY OTHER PRODUCTS OF THE DIPHTHERIA BACILLUS.
The detection of toxigenic Corynebacterium ulcerans from cats with nasal inflammation in Japan.
The development of endometriosis in a murine model is dependent on the presence of dendritic cells.
The different behavior of diphtheria toxin, modeccin and ricin in HeLa cells infected with Trypanosoma cruzi.
The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin.
The diphthamide modification pathway from Saccharomyces cerevisiae--revisited.
The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers.
The diphtheria toxin channel-forming T-domain translocates its own NH2-terminal region and the catalytic domain across planar phospholipid bilayers.
The diphtheria toxin structural gene.
The diphtheria toxin transmembrane domain as a pH sensitive membrane anchor for human interleukin-2 and murine interleukin-3.
The diphtheria toxin/urokinase fusion protein (DTAT) is selectively toxic to CD87 expressing leukemic cells.
The E5 oncoprotein of human papillomavirus type 16 inhibits the acidification of endosomes in human keratinocytes.
The earliest intrathymic precursors of CD8?(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
The effect of anti-CD3-immunotoxin on T lymphocyte function in vitro.
The effect of cortisone on the survival of guinea pigs inoculated with diphtheria toxin.
The effect of diphtheria toxin on carnitine metabolism in the heart.
The effect of diphtheria toxin on primary cell cultures of the adult human liver.
The effect of diphtheria toxin on pulsating rabbit, guinea pig, human and rat heart cell cultures.
The effect of diphtheria toxin on the cellular uptake and efflux of L-carnitine. Evidence for a protective effect of prednisolone.
THE EFFECT OF DIPHTHERIA TOXIN ON THE METABOLISM OF HELA CELLS : II. EFFECT ON NUCLEIC ACID METABOLISM.
The effect of diphtheria toxin on the metabolism of HeLa cells.
The effect of direct translocation across endosomes on the cytotoxicity of the recombinant protein e23sFv-Fdt-casp6 to HER2 positive gastric cancer cells.
The effect of high pH upon diphtheria toxin conformation and model membrane association: role of partial unfolding.
The effect of hypophysectomy on the reactions of animals to diphtheria toxin.
The effect of immunotoxin against human glioma cells.
The Effect of Physicochemical Modification on the Function of Antibodies Induced by Anti-Nicotine Vaccine in Mice.
The effect of receptor rapid-internalization signals on diphtheria toxin endocytosis and cell sensitivity.
The effect on solutions of diphtheria toxin and diphtheria antitoxin of contact with certain surfaces.
The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres.
The effects of ascorbic acid on diphtheria toxin and intoxicated HeLa cells.
The effects of diphtheria toxin on developing peripheral myelin in culture.
The effects of diphtheria toxin on guinea-pig myocardial protein synthesis.
The effects of diphtheria toxin on the Cecropia silkworm.
The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2.
The effects of inhibitors upon pore formation by diphtheria toxin and diphtheria toxin T domain.
The efficacy of diphtheria-growth factor fusion proteins is enhanced by co-administration of cytosine arabinoside in an immunodeficient mouse model of human acute myeloid leukemia.
The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.
The exotoxins of Corynebacterium ulcerans.
The fate of 131 I-labelled diphtheria toxin and toxoid in the skin of immune and allergic guinea-pigs.
The Father, Son and Cholix Toxin: The Third Member of the DT Group Mono-ADP-Ribosyltransferase Toxin Family.
The fixation of diphtheria toxin to skin tissue with special reference to the action of circulating antitoxin.
The formation of a ternary complex between diphtheria toxin, aminoacyltransferase II, and diphosphopyridine nucleotide.
THE FRACTIONAL PRECIPITATION OF THE GLOBULIN AND ALBUMIN OF NORMAL HORSE'S SERUM AND DIPHTHERIA ANTITOXIC SERUM, AND THE ANTITOXIC STRENGTH OF THE PRECIPITATES.
The frequency and distribution of apoptosis induced by three non-carcinogenic agents in mouse colonic crypts.
The frequency of mutants in human fibroblasts UV-irradiated at various times during S-phase suggests that genes for thioguanine- and diphtheria toxin-resistance are replicated early.
The Fur iron regulator-like protein is cryptic in the hyperthermophilic archaeon Thermococcus kodakaraensis.
The geometry of diphtheria toxoid CRM197 channel assessed by thiazolium salts and nonelectrolytes.
The glial scar-monocyte interplay: a pivotal resolution phase in spinal cord repair.
The Hidden Nature of Protein Translational Control by Diphthamide - the secrets under the leather.
The histidine residue of codon 715 is essential for function of elongation factor 2.
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.
The IL-2 diphtheria toxin fusion protein denileukin diftitox modulates the onset of diabetes in female nonobese diabetic animals in a time-dependent manner and breaks tolerance in male nonobese diabetic animals.
The immune response to booster vaccination against diphtheria toxin at age 18-21 years.
The immunizing Effect on Guinea-Pigs of Small Doses of Diphtheria Toxin.
THE IMMUNIZING POWER OF NUCLEOHISTON AND OF HISTON.
The Immunogenicity and Anti-Tumor Efficacy of a Rationally Designed EGFR Vaccine.
The Immunogenicity and Anti-tumor Efficacy of a Rationally Designed Neoantigen Vaccine for B16F10 Mouse Melanoma.
THE IMMUNOLOGICAL SIGNIFICANCE OF COLOSTRUM : I. THE RELATION BETWEEN COLOSTRUM, SERUM, AND THE MILK OF COWS NORMAL AND IMMUNIZED TOWARDS B. COLI.
The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on antibody responses to routine immunisations given in infancy: Secondary analysis of a randomised controlled trial.
The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy.
The increasing complexity of the oncofetal h19 gene locus: functional dissection and therapeutic intervention.
THE INDUCED SUSCEPTIBILITY OF THE GUINEA-PIG TO THE TOXIC ACTION OF THE BLOOD SERUM OF THE HORSE.
The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice.
The induction of systemic and mucosal immune responses following the subcutaneous immunization of mature adult mice: characterization of the antibodies in mucosal secretions of animals immunized with antigen formulations containing a vitamin D3 adjuvant.
The influence of bacterial exotoxins and endotoxins on the phagocytic activity of human macrophages in culture.
The influence of conjugation variables on the design and immunogenicity of a glycoconjugate vaccine against Salmonella Typhi.
The Inhibition of Insulin Action by Toxæmias and its Explanation.—I: The Effect of Diphtheria Toxin on Blood-Sugar and Insulin Action in Rabbits*.
The inhibitory effect of diphtheria toxin on amino acid incorporation by a bacterial cell-free system.
The interaction between actin and FA fragment of diphtheria toxin.
The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34+CD123+ cells from acute myeloid leukemia/myelodysplastic syndrome patients and healthy donors.
The internodal axon membrane: electrical excitability and continuous conduction in segmental demyelination.
The interrelationship of the antitoxin titre in the blood of irradiated animals and their resistance to diphtheria toxin.
The intersubunit disulfide bridge of ricin is essential for cytotoxicity.
The iron enzymes of C. diphtheriae and their possible relation to diphtheria toxin.
The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum.
The life and death of translation elongation factor 2.
The M2a macrophage subset may be critically involved in the fibrogenesis of endometriosis in mice.
The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity.
The mechanism of ADP-ribosylation of elongation factor 2 catalyzed by fragment A from diphtheria toxin.
THE MECHANISM OF ANAPHYLATOXIN FORMATION : STUDIES ON FERMENT ACTION. XV.
The mechanism of parenchymatous degeneration produced by diphtheria toxin.
The Membrane Topography of the Diphtheria Toxin T Domain Linked to the A Chain Reveals a Transient Transmembrane Hairpin and Potential Translocation Mechanisms.
The mutagenic effects of 7,12-dimethylbenz[a]anthacene, 3-methylcholanthrene and benzo[a]pyrene to the developing Syrian hamster fetus measured by an in vivo/in vitro mutation assay.
The mutation studies of mutagen-sensitive and DNA repair mutants of Chinese hamster fibroblasts.
The N-terminal alpha-helix of fragment B of diphtheria toxin promotes translocation of fragment A into the cytoplasm of eukaryotic cells.
The neuroregenerative capacity of olfactory stem cells is not limitless: implications for aging.
THE NEUTRALIZATION OR DESTRUCTION OF DIPHTHERIA TOXIN BY TISSUE.
The number of subunits comprising the channel formed by the T domain of diphtheria toxin.
The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step.
The part played by Protein-free Digestion Products and by Meat Infusion in Diphtheria Toxin Production *.
The PentaFOLD 3.0 algorithm for the selection of stable elements of secondary structure to be included in vaccine peptides.
The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells.
The pH-dependent conformational change of diphtheria toxin.
The pH-Dependent Trigger in Diphtheria Toxin T Domain Comes with a Safety Latch.
The pollen-specific DEFH125 promoter from Antirrhinum is bound in vivo by the MADS-box proteins DEFICIENS and GLOBOSA.
The post-translational trimethylation of diphthamide studied in vitro.
The preparation of stable, biologically active B fragment of diphtheria toxin.
THE PRODUCTION OF ARTERIOSCLEROSIS AND GLOMERULONEPHRITIS IN THE RABBIT BY INTRAVENOUS INJECTIONS OF DIPHTHERIA TOXIN.
The production of diphtheria toxin by submerged culture in shaking flasks.
THE PRODUCTION OF DIPHTHERIA TOXIN.
The production of high potency diphtheria toxin in submerged culture in relatively simple equipment using a semisynthetic medium.
The protective effect of nerve growth factor in nerve tissue cultures exposed to diphtheria toxin.
The protective mechanism of action of amines in diphtheria toxin treated Vero cells.
The Purification and Concentration of Diphtheria Toxin: I. Evaluation of Previous Methods; Description of a New Procedure.
The Purification and Concentration of Diphtheria Toxin: II. Observations on the Nature of the Toxin.
The Purification and Concentration of Diphtheria Toxin: III. Separation of Toxin from Bacterial Protein.
The purification of diphtheria toxin and the isolation of crystalline toxin-protein.
The reaction of bacterial toxins with formaldehyde and its use for antigen stabilization.
The reaction of diphtheria toxin with horse antitoxin in the region of antibody excess.
THE REACTIONS BETWEEN BACTERIA AND ANIMAL TISSUES UNDER CONDITIONS OF ARTIFICIAL CULTIVATION.
THE REACTIONS OF HALICYSTIS AND OF VALONIA TO INJECTIONS OF CERTAIN PROTEINS.
The recombinant protein combined vaccine based on the fragment C of tetanus toxin and the cross-reacting material 197.
THE RELATION OF THE TOXICITY OF DIPHTHERIA TOXIN TO ITS NEUTRALIZING VALUE UPON ANTITOXIN AT DIFFERENT STAGES IN THE GROWTH OF CULTURE.
The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD
The resistance of non-adrenalectomized rats to diphtheria toxin with and without adrenal cortical hormone treatment.
The Resistance of Rats to Diphtheria Toxin.
The response of cultured mammalian cells to diphtheria toxin. I. Amino acid transport, accumulation, and incorporation in normal and intoxicated sensitive cells.
The response of cultured mammalian cells to diphtheria toxin. II. The resistant cell: enhancement of toxin action by poly-L-ornithine.
The retinal environment induces microglia-like properties in recruited myeloid cells.
The role of adjuvants in the efficacy of a peptide vaccine for myasthenia gravis.
The role of intravenous immunoglobulin therapy in autoimmune and inflammatory disorders.
The Role of M2 Macrophages in the Progression of Chronic Kidney Disease following Acute Kidney Injury.
The role of Olfaction in MCH-regulated spontaneous maternal responses.
The Role of Osteocytes in Bone Resorption during Orthodontic Tooth Movement.
The role of proline 345 in diphtheria toxin translocation.
The role of proteases and exotoxin A in the pathogenicity of Pseudomonas aeruginosa infections.
The role of the diphthamide-containing loop within eukaryotic elongation factor 2 in ADP-ribosylation by Pseudomonas aeruginosa exotoxin A.
The role of the diphtheria toxin receptor in cytosol translocation.
THE ROLE OF THE RETICULO-ENDOTHELIAL SYSTEM IN IMMUNITY : IV. THE ACTION OF DIPHTHERIA TOXIN IN SPLENECTOMIZED AND BLOCKED MICE.
The Schick Dose of Diphtheria Toxin as a Secondary Stimulus.
The second intron of AGAMOUS drives carpel- and stamen-specific expression sufficient to induce complete sterility in Arabidopsis.
The sensitivity of cystic fibrosis cells to diphtheria toxin.
The Shiga toxin B-subunit targets antigen in vivo to dendritic cells and elicits anti-tumor immunity.
The short-term impact of each primary dose of pneumococcal conjugate vaccine on nasopharyngeal carriage: Systematic review and meta-analyses of randomised controlled trials.
The site of integration of the herpes simplex virus type 1 thymidine kinase gene in human cells transformed by an HSV-1 DNA fragment.
The spatial distribution of excitability and membrane current in normal and demyelinated mammalian nerve fibres.
The spatial distribution of immunotoxins in solid tumors: assessment by quantitative autoradiography.
The spectrum of virus resistance of a KB cell strain resistant to diphtheria toxin.
The src homology 3-like domain of the diphtheria toxin repressor (DtxR) modulates repressor activation through interaction with the ancillary metal ion-binding site.
The structure of diphtheria toxin as a guide to rational design.
The Temporal and Spatial Dynamics of Foxp3+ Treg Cell-Mediated Suppression during Contact Hypersensitivity Responses in a Murine Model.
The Terminator mouse is a diphtheria toxin-receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages.
The therapeutic potential of attenuated diphtheria toxin delivered by an adenovirus vector with survivin promoter on human lung cancer cells.
The transmembrane domain of diphtheria toxin improves molecular conjugate gene transfer.
The Trojan Horse of the microbiological arms race: phage-encoded toxins as a defence against eukaryotic predators.
The use of beef residue hydrolysate for the production of potent diphtheria toxin.
The use of yeast autolysate as activator in the preparation of diphtheria toxin.
Therapeutic effects of genetically engineered toxin (DAB486IL-2) in patient with chronic lymphocytic leukaemia.
Therapeutic targeting with DABIL-4 depletes myeloid suppressor cells in 4T1 triple-negative breast cancer model.
Thermal stability of different forms of diphtheria toxin.
Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain.
Thioredoxin reductase inhibitor auranofin prevents membrane transport of diphtheria toxin into the cytosol and protects human cells from intoxication.
Three-dimensional profiles for analysing protein sequence-structure relationships.
Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors.
Thyrotoxicosis after denileukin diftitox therapy in patients with mycosis fungoides.
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector.
Tight transcriptional regulation of foreign genes in insect cells using an ecdysone receptor-based inducible system.
Tightly-regulated suicide gene expression kills PSA-expressing prostate tumor cells.
Time-dependent alterations in NOS1 immunoreactivity in feline pudendal motoneurons following retrograde axonal transport of diphtheria toxin.
Tissue distribution of mRNA for heparin-binding epidermal growth factor.
Tissue nonautonomous effects of fat body methionine metabolism on imaginal disc repair in Drosophila.
Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury.
Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice.
Tissue-specific control of latent CMV reactivation by regulatory T cells.
Titration of diphtheria toxin, antitoxin and toxoid in tissue culture.
TNF-{alpha}-dependent Regulation of Acute Pancreatitis Severity by Ly-6Chi Monocytes in Mice.
To be helped or not helped, that is the question.
Topography of diphtheria toxin A chain inserted into lipid vesicles.
Topography of diphtheria Toxin's T domain in the open channel state.
Topography of helices 5-7 in membrane-inserted diphtheria toxin T domain: identification and insertion boundaries of two hydrophobic sequences that do not form a stable transmembrane hairpin.
Topography of the hydrophilic helices of membrane-inserted diphtheria toxin T domain: TH1-TH3 as a hydrophilic tether.
Topography of the TH5 Segment in the Diphtheria Toxin T-Domain Channel.
Topology of diphtheria toxin B fragment inserted in lipid vesicles.
Topology of diphtheria toxin in lipid vesicle membranes: a proteolysis study.
Towards a recombinant vaccine against diphtheria toxin.
Towards small molecule inhibitors of mono-ADP-ribosyltransferases.
Toxic, DNA-damaging and mutagenic activity of epichlorohydrin on human cells cultured in vitro.
Toxicity and immunochemical properties of I131 trace labelled diphtheria toxin.
Toxicity of diphtheria toxin for lymphoblastoid cells is increased by conjugation to antilymphocytic globulin.
Toxicity of ricin, diphtheria toxin and alpha-Amanitin for Acanthamoeba castellanii (1983).
Toxicity to mouse L cell shown by reassembled HVJ (Sendai virus) envelopes containing nontoxic mutant proteins of diphtheria toxin [proceedings]
Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.
Toxicology and pharmacokinetics of DT388IL3, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human interleukin 3 (IL3), in cynomolgus monkeys.
Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys.
Toxigenic Corynebacterium ulcerans isolated from a free-roaming red fox (Vulpes vulpes).
Toxigenic Corynebacterium ulcerans isolated from a hunting dog and its diphtheria toxin antibody titer.
Toxin binding site of the diphtheria toxin receptor: loss and gain of diphtheria toxin binding of monkey and mouse heparin-binding, epidermal growth factor-like growth factor precursors by reciprocal site-directed mutagenesis.
TOXIN-ANTITOXIN REACTION WITHOUT NEUTRALIZATION.
Toxin-antitoxin selection for isolating somatic cell fusion products between any cell types.
Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide.
Toxin-labeled monoclonal antibodies.
Toxin-Mediated siRNA Delivery.
Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway.
Trangenic and knockout rodents: novel insights into mechanisms of body weight regulation.
Transcription analysis and nucleotide sequence of tox promoter/operator mutants of corynebacteriophage beta.
Transcutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine.
Transfer agent of immunity. IV. Antibody formation against diphtheria toxin by an immune ribonucleic acid fraction.
Transfer of delayed hypersensitivity to diphtheria toxin in man.
Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas.
Transferrin receptor-mediated endocytosis: a useful target for cancer therapy.
Transgenic mice carrying the diphtheria toxin A chain gene under the control of the granzyme A promoter: expected depletion of cytotoxic cells and unexpected depletion of CD8 T cells.
Transgenic mice expressing a fully nontoxic diphtheria toxin mutant, not CRM197 mutant, acquire immune tolerance against diphtheria toxin.
Transgenic mice expressing the diphtheria toxin receptor are sensitive to the toxin.
Transient Depletion of CD169(+) Cells Contributes to Impaired Early Protection and Effector CD8(+) T Cell Recruitment against Mucosal Respiratory Syncytial Virus Infection.
Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive ? Cell Autoimmunity in Genetically Susceptible DEREG Mice.
Transient hypogammaglobulinemia of infancy: Five new cases, review of the literature and redefinition.
Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Transition metal ion activation of DNA binding by the diphtheria tox repressor requires the formation of stable homodimers.
Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin.
Transition State Structure for the Hydrolysis of NAD Catalyzed by Diphtheria Toxin.
Translating ribosomes inhibit poliovirus negative-strand RNA synthesis.
Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance.
Translation of the genes for the structural proteins of alphaviruses.
Translationally-controlled tumor protein activates the transcription of Oct-4 in kidney-derived stem cells.
Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore.
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage.
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels.
Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain.
Transmembrane topography of the nicotinic acetylcholine receptor delta subunit.
Transmembrane transport of diphtheria toxin, related toxins, and colicins.
Transmission of toxigenic Corynebacterium diphtheriae by a fully immunised resident returning from a visit to West Africa, United Kingdom, 2017.
Transplantation of embryonic stem cell-derived endodermal cells into mice with induced lethal liver damage.
Transport of diphtheria toxin A fragment across the plasma membrane.
Transport of diphtheria toxin fragment A across mammalian cell membranes.
Transposon tagging and the study of root development in Arabidopsis.
Treatment of blastic plasmacytoid dendritic cell neoplasm.
Treatment of FL cells with neuraminidase stimulating the sensitivities to diphtheria toxin and ricin toxin [proceedings]
Treatment of Intestinal Inflammation With Epicutaneous Immunotherapy Requires TGF-? and IL-10 but Not Foxp3+ Tregs.
Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report.
Treatment of refractory peripheral T-cell lymphoma with denileukin diftitox (ONTAK).
Treg depletion attenuates the severity of skin disease from ganglionic spread after HSV-2 flank infection.
Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.
Tregs Modulate Lymphocyte Proliferation, Activation, and Resident-Memory T-Cell Accumulation within the Brain during MCMV Infection.
Triglyceride behaviour in liver and serum of rabbits treated with diphtheria toxin.
Troglitazone action is independent of adipose tissue.
Trojan horse or proton force: finding the right partner(s) for toxin translocation.
Truncated Diphtheria Toxin DT390 Enhances the Humoral Immunogenicity of Porcine Circovirus Type 2 Capsid Antigen in Mice.
Tubulointerstitial fibrosis can sensitize the kidney to subsequent glomerular injury.
Tumor Lymphatic Function Regulates Tumor Inflammatory and Immunosuppressive Microenvironments.
Tumor necrosis factor alpha- and inducible nitric oxide synthase-producing dendritic cells are rapidly recruited to the bladder in urinary tract infection but are dispensable for bacterial clearance.
Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors.
Tumoral immune suppression by macrophages expressing fibroblast activation protein-? and heme oxygenase-1.
Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
Tumour lysis as a factor affecting blood levels of CEA.
Two elongation factors from the extremely halophilic archaebacterium Halobacterium cutirubrum. Assay systems and purification at high salt concentrations.
Two Japanese Corynebacterium ulcerans isolates from the same hospital: Ribotype, toxigenicity, and serum antitoxin titre.
Two pathways of transferrin recycling evident in a variant of mouse LMTK- cells.
Two serologic markers to monitor the engraftment, growth, and treatment response of human leukemias in severe combined immunodeficient mice.
Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation.
Two transgenic approaches to define the cell lineages in endocrine pancreas development.
Type 2 Innate Immunity in Helminth Infection Is Induced Redundantly and Acts Autonomously following CD11c+ Cell Depletion.
Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin.
Ultrastructural and biochemical aspects of the myocardium in guinea-pigs treated with diphtheria toxin.
Ultrastructural changes in the region of the node of ranvier in the rat caused by diphtheria toxin.
Ultrastructural features of viral leukoencephalomyelitis of goats.
Ultrastructural localization of interferon receptors on the surfaces of cultured cells and erythrocytes.
Ultraviolet light induction of diphtheria toxin-resistant mutants of normal and xeroderma pigmentosum human fibroblasts.
Ultraviolet light induction of diphtheria toxin-resistant mutations in normal and DNA repair-deficient human and Chinese hamster fibroblasts.
Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century.
Unfolding of diphtheria toxin. Identification of hydrophobic sites exposed on lowering of pH by photolabeling.
Unique chemical reactivity of His-21 of CRM-197, a mutated diphtheria toxin.
United States Standard Diphtheria Toxin for the Schick Test and the Erythema Potency Assay for the Schick Test Dose.
United States standard diphtheria toxin for the Schick text and the erythema potency assay for the Schick text dose.
Universal toxin-based selection for precise genome engineering in human cells.
Unraveling the role of podocyte turnover in glomerular aging and injury.
Unusual conformation of nicotinamide adenine dinucleotide (NAD) bound to diphtheria toxin: a comparison with NAD bound to the oxidoreductase enzymes.
Unusual sensitivity of rabbit cells to a nonbinding diphtheria toxin fragment.
Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal.
Update in childhood acute myeloid leukemia: recent developments in the molecular basis of disease and novel therapies.
Uptake of diphtheria toxin and its fragment A moiety by mammalian cells in culture.
Uptake of fluorochrome-labelled exotoxins by different cell types in culture.
Urea signalling to immediate-early gene transcription in renal medullary cells requires transactivation of the epidermal growth factor receptor.
Urethane and N-nitrosodiethylamine are mutagenic for the Syrian hamster fetus.
Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury.
Urine podocin:nephrin mRNA ratio (PNR) as a podocyte stress biomarker.
Urine podocyte mRNAs mark progression of renal disease.
Urokinase Receptor (uPAR) Ligand based Recombinant Toxins for Human Cancer Therapy.
Use of a Novel Integrase-Deficient Lentivirus for Targeted Anti-Cancer Therapy With Survivin Promoter-Driven Diphtheria Toxin A.
Use of an oral diphtheria vaccine in human.
Use of biotinylated NAD to label and purify ADP-ribosylated proteins.
Use of diphtheria toxin and toxoid in the study of immediate and delayed hypersensitivity in man.
Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer.
Use of H19 regulatory sequences for targeted gene therapy in cancer.
Use of imaged capillary isoelectric focusing technique in development of diphtheria toxin mutant CRM197.
Use of preclinical models to assess the therapeutic potential of new drug candidates for bladder cancer.
Use of silkworm larvae to study pathogenic bacterial toxins.
Use of streamline chelating for capture and purification of poly-His-tagged recombinant proteins.
Use of synthetic peptides and site-specific antibodies to localize a diphtheria toxin sequence associated with ADP-ribosyltransferase activity.
Use of the Rad51 promoter for targeted anti-cancer therapy.
Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy.
Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells.
Use of Trp mutations to evaluate the conformational behavior and membrane insertion of A and B chains in whole diphtheria toxin.
Utilization of Rad51C promoter for transcriptional targeting of cancer cells.
UV-light-induced mutations in synchronous CHO cells.
Vaccination against Group B streptococcus.
Vaccination of heifers with anaflatoxin improves the reduction of aflatoxin b1 carry over in milk of lactating dairy cows.
Vaccination of infants with a four-dose and a three-dose vaccination schedule.
Vaccines Through Centuries: Major Cornerstones of Global Health.
Vaccines, emerging viruses, and how to avoid disaster.
Variable aberrant cDNAs in single diphtheria toxin-resistant human fibroblasts.
Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells.
Variable region expression in the antibody responses of infants vaccinated with Haemophilus influenzae type b polysaccharide-protein conjugates. Description of a new lambda light chain-associated idiotype and the relation between idiotype expression, avidity, and vaccine formulation. The Collaborative Vaccine Study Group.
Variant Diphtheria Toxin-Interleukin-3 Fusion Proteins with Increased Receptor Affinity Have Enhanced Cytotoxicity against Acute Myeloid Leukemia Progenitors.
Variation in Susceptibility of Guinea-pigs to Diphtheria Toxin.
Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells.
Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury.
Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo.
Vascular protection by chloroquine during brain tumor therapy with Tf-CRM107.
Vendor-specific microbiome controls both acute and chronic murine lung allograft rejection by altering CD4+ Foxp3+ regulatory T cell levels.
Vestibular and Auditory Hair Cell Regeneration Following Targeted Ablation of Hair Cells With Diphtheria Toxin in Zebrafish.
Vi-CRM 197 as a new conjugate vaccine against Salmonella Typhi.
Vibrio cholerae O139 conjugate vaccines: synthesis and immunogenicity of V. cholerae O139 capsular polysaccharide conjugates with recombinant diphtheria toxin mutant in mice.
Visualization and ablation of phenylethanolamine N-methyltransferase producing cells in transgenic mice.
Voltage-dependent gating properties of the channel formed by E. coli hemolysin in planar lipid membranes.
Water accessibility, aggregation, and motional features of polysaccharide-protein conjugate vaccines.
What is diphtheria toxin.
Whole Genome Sequencing for Surveillance of Diphtheria in Low Incidence Settings.
Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells.
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
X-ray grade crystals of diphtheria toxin.
X-ray grade crystals of the enzymatic fragment of diphtheria toxin.
Xenogeneic thymus transplantation in a pig-to-baboon model.
YBR246W is required for the third step of diphthamide biosynthesis.
Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins.
Zn(II) Stimulation of Fe(II)-Activated Repression in the Iron-Dependent Repressor from Mycobacterium tuberculosis.
[9th symposium on bacterial toxins. 1. On the mechanism of action of toxins. B. Cellular level. 4. On the mechanism of toxic action of diphtheria toxin on Ehrlich ascites tumor cells.]
[A case of diphtheria in the Netherlands due to an infection with Corynebacterium ulcerans]
[A case report of pharyngeal diphtheria]
[A study of diphtheria toxin and anatoxin by the method of electron paramagnetic resonance]
[A study of some metabolic processes of the failing heart in experiment. I. Changes of acetylcholine metabolism after heart damage by diphtheria toxin.]
[A study of some metabolic processes of the failing heart in experiment. II. Changes of some components involved in the synthesis of acetylcholine after heart damage by diphtheria toxin.]
[A study of some metabolic processes of the failing heart in experiment. III. Change of water and electrolyte metabolism in the heart after damage by diphtheria toxin.]
[Accessibility of tryptophanyl residues of diphtheria toxin fragment A (proceedings)]
[Action and production of diphtheria toxin, with special reference to its analysis using the cross-reacting toxin material]
[Action of decamethoxin on diphtherial exotoxin]
[Action of diphtheria toxin on oxidation of cytochrome C]
[Action of diphtheria toxin on poly-U-directed polyphenylalanine synthesis in chick-embryo ribosomes]
[Action of diphtheria toxin on rat hemoglobin. Electrophoretic and chromatographic investigations.]
[Action of diphtheria toxin on the isolated heart]
[Action of prednisolone in experimental diphtheria toxin poisoning in guinea pigs. II. Results of histological studies of the internal organs]
[Activation of the cell proliferation program by acidic fibroblast growth factor (aFGF)]
[Adult T cell leukemia-lymphoma (ATL)].
[AMINO ACID COMPOSITION OF PURIFIED DIPHTHERIA TOXIN.]
[Analyses of cell function using diphtheria toxin]
[Anchoring cytokines to cancer cells using diphtheria toxin: better than immunotherapy by gene transfer?]
[Antagonistic effect of salmine, papain and thymus histone on the inflammatory action of diphtheria toxin on guinea pig skin.]
[Antibodies against vaccine-preventable diseases in pregnant women and their offspring. Diphtheria, pertussis, tetanus]
[Antitoxic properties of monoclonal antibodies against diphtheria toxin]
[Antitumor effect of diphtheria toxin on Ehrlich ascites tumor in mice]
[Application of novel drug delivery system, fusogenic liposome, for cancer therapy]
[Assessment of different regimens of diphtheria serotherapy]
[ATTEMPT AT DEMONSTRATION OF DISULFIDE BONDS IN TETANUS TOXIN AND DIPHTHERIA TOXIN.]
[Attempt of explanation of the mechanism of cerebral damage by diphtheria toxin (isotope studies). II. Distribution of I-131-albumin in the brain tissue of cats infected by diphtheria toxin]
[Binding between hemagglutinin and diphtheria toxin.]
[Biochemical research on the heart in experimental poisoning with diphtheria toxin.]
[Biological activities of diphtheria toxin]
[Biomolecular aspects of adult T-cell leukemia]
[Biosynthesis and function of diphtheria toxin and its related proteins (author's transl)]
[Cell model for the study of receptor and regulatory functions of human proHB-EGF].
[Cell nucleus volumes of the adrenal cortex and 17-hydroxycorticosteroid excretion in guinea pigs after long-term cortisone pretreatment and after diphtheria toxin poisoning.]
[Certification of a kit for immunologic tests]
[Changes in diphtheria toxin induced by benzene and its derivatives and their effect on toxin-toxoid binding.]
[Changes in myocardial ultrastructure in diphtheria intoxication]
[Changes in the corticosteroid hormone content of guinea pig organs and tissues following diphtheria toxin intoxication]
[Changes of various lipid fractions in experimental intoxication with diphtheric and tetanic toxins]
[Chemica groups of diphtheria toxin bound by formaldehyde during the detoxication process]
[Chemical structure of diphtheria toxin and toxoid. IV. Epsilon-amino groups of lysine in protein of diphtherial toxin and toxoid]
[Chlorophyll. II. Behavior in relation to diphtheria toxin.]
[Classical pseudomembranous diphtheria caused by Corynebacterium ulcerans]
[Cloning and expression of the gene for diphtheria toxin and its subunits in Escherichia coli]
[Cloning in Escherichia coli of the mutant gene coding the diphtheria toxin]
[Cloning of the structural gene for diphtheria toxin from Corynebacterium diphtheriae PW8 and expression of its deletion derivative in E. coli]
[Cloning, expression and cytotoxin to human lens epithelial cells of targeting toxin DT389-hbFGF]
[Comparative analysis of the DNA of Corynebacterium diphtheriae phages and the cloning of the gene determining diphtheria toxin synthesis]
[Comparative efficacy of homologous and heterologous biologicals against diphtheria]
[Comparative studies of histopathologic changes in the central nervous system and internal organs of guinea pigs poisoned with diphtheria toxin]
[COMPARATIVE STUDIES ON DIPHTHERIA TOXIN AND ANATOXIN PREPARATIONS.]
[Comparison of dermonecrotic activity of 2 forms of specific diphtheria toxin]
[Comparison of three methods in determining the antibody against diphtheria toxin]
[Construction and expression of the fusion protein DT389-hIL-13 and its cytotoxicity to glioma cell lines]
[Construction of derivatives of the diphtheria toxin gene and their expression in Escherichia coli cells]
[Construction of immune library of murine immunoglobulin genes and screening of single-chain Fv-antibodies to diphtheria toxin B subunit]
[Construction of plasmids coding for diphtheria toxin fragments]
[Content of serotonin and histamine in rat submandibular gland under conditions of botulism and toxic diphtheria]
[Control of Haemophilus influenzae infections]
[Corynebacterium diphtheriae nontoxigenic strain carrying the gene of diphtheria toxin]
[Corynebacterium ulcerans infection in roe deer (Capreolus capreolus)].
[Cytological changes in the anterior lobe of the guinea pig pituitary after administration of diphtheria toxin or pyrifer.]
[Cytomorphological and enzymocytochemical study of the changes induced by diphtheria toxin in monkey kidney cultures]
[Cytotoxic action of diphtheria toxin and titration of diphtheria antitoxin on tissue cultures.]
[Cytotoxicity of the B subunit of diphtheria toxin to human histocytic lymphoma U937]
[Demonstration of tyrosine in the enzymatic site of diphtheria toxin]
[Design and expression of a diphtheria toxin hybrid protein and human interleukin-2 gene in Escherichia coli]
[Desoxycorticosterone and cortisone in intoxication with diphtheria toxin.]
[Detection and determination of diphtheria toxin in the blood of patients with diphtheria by means of the passive hemagglutination test]
[Detection by molecular biology techniques of diphtheria toxin production in corynebacteria]
[Detection of diphtheria toxin and its degradation products by using immunoenzyme analysis]
[Detection of diphtheria toxin with plate test. I. Technic.]
[Detection of diphtheria toxin with plate test. II..]
[Detection of LOS-specific antibody-secreting cells by ELISPOT assay]
[DETERMINATION OF DESOXYRIBONUCLEASE ACTIVITY AS AN INDICATOR OF THE TOXIGENICITY OF DIPHTHERIA BACTERIA.]
[Development of monoclonal latex diagnostic kit for diphtheria toxin and toxoid detection]
[Development of recombinant scFv-antibodies against diphtheria toxin using phage display system]
[Diagnostic value of Diamed AG latex gel kit for detection of diphtheria toxin]
[Differences in immunological reactivity between diphtheria toxin and anatoxin.]
[Diphtheria toxin and antitoxin. 3. Immunologic effectiveness of sorbed preparations made on the basis of highly-purified diphtheria toxoid]
[Diphtheria toxin is carried into the cell by a growth factor]
[Diphtheria toxin receptor complex]
[Diphtheria toxin receptor]
[Diphtheria toxin titration using "Staphylococcus aureus" protein A (author's transl)]
[Diphtheria toxin. Effects on sensitive cells, structure of the toxin molecule and mechanism of its action]
[Diphtheria toxin. Its structure and mode of action]
[Diphtheria toxin.]
[Diphtheria toxin: ability to agglutinate human leukemia cells]
[Diphtheria toxin: the molecular biology of an infection]
[Diphtheria toxin]
[Diphtheria: a 'forgotten' disease?]
[Distinct vascular niches determine hematopoietic stem cell fate].
[DNAase activity of the diphtheria bacteria as one of the signs of their pathogenicity]
[Dynamics of ultrastructural changes in guinea pig cardiomyocytes in experimental diphtheria intoxication]
[Effect of ACTH on cutaneous necrotic lesions due to diphtheria toxin in the guinea pig.]
[Effect of burns and diphtheria toxin, uranium nitrate and mercuric chloride on the juxtaglomerular apparatus; personal research.]
[Effect of cytochalasin D, diphtheria toxin, and ricin on the localization of eukaryotic elongation factor 2 along actin filament bundles in fibroblasts]
[Effect of diphtheria toxin on cell metabolism]
[Effect of diphtheria toxin on guinea pig macrophages. I. Sensitivity of peritoneal and pulmonary macrophages to diphtheria toxins]
[Effect of diphtheria toxin on guinea pig macrophages. II. Phagocytic activity of peritoneal macrophages]
[Effect of diphtheria toxin on guinea pig macrophages]
[Effect of diphtheria toxin on local inflammatory reaction. Part II. On the mechanism of local action of diphtheria toxins.]
[Effect of diphtheria toxin on protein metabolism; studies with use of carbon 14 labeled lysine in guinea pigs.]
[Effect of diphtheria toxin on the Brachet (RNA) and Feulgen (DNA) reactions in the cells of renal tubules]
[Effect of diphtheria toxin on the isolated and perfused liver in vitro: preliminary observations]
[Effect of diphtheria toxin on the phagocytosis of Corynebacterium diphtheriae in vivo]
[Effect of diphtheria toxin on the release and extractability of histones from the liver cell nuclei of guinea pigs]
[Effect of diphtheria toxin on the viability of phagocytes and B-lymphocytes in animals sensitive and insensitive to it]
[Effect of durabolin on the mortality of guinea pigs receiving diphtheria toxin]
[Effect of kollidon on diphtheria toxin.]
[Effect of pituitary-thyroid system on pleural exudation following diphtheria toxin in guinea pigs.]
[Effect of potassium and sodium ions on the synthesis of diphtheria toxin.]
[Effect of prolonged preventive cortisone treatment on hemorrhagic necrosis of the adrenal cortex after diphtheria toxin poisoning.]
[Effect of roentgen rays on diphtheria toxin.]
[Effect of the degree of culture aeration on diphtheria toxin production and growth of 3 variants of Corynebacterium diphtheriae PW 8]
[Effect of triiodotyronine on formation of pleural exudates in guinea pig following administration of diphtheria toxin.]
[Effects of diphtheria and tetanus toxins on liver regeneration in the rat]
[Effects of neurobilil on acute experimental poisoning with diphtheria toxin in guinea pigs and results of its use jointly with diphtheria antitoxin]
[Electromyographical study of paralysis caused by diphtheria toxin in guinea pigs.]
[Electron microscope study on the liver cell lesion in diphtheria toxin poisoning.]
[Emergency laboratory diagnosis of diphtheria]
[Endosomes and toxin translocation]
[Enzyme immunoassay of immune complexes formed in vitro via interactions of serum antibodies with diphtheria toxin]
[Expression, purification and characterization of diphtheria toxin mutant CRM197 in Eschrichia coli].
[Expression, purification and specific monoclonal antibodies preparation of diphtheria toxin A fragment]
[Features of the structure of catalytic subunits of toxins, inhibiting protein synthesis. I. The effect of pH and interaction with the B-chain of ricin]
[Fluorescent derivatives of diphtheria toxin subunit B and their interaction with Vero cells]
[Formation of a regeneration stimulus following after submandibular gland and liver injury in the presence of total sympathetic nervous system suppression]
[GEL FILTRATION OF UNPURIFIED DIPHTHERIA TOXIN.]
[Generation of mouse models of human disease using a diphtheria toxin receptor-mediated conditional cell knockout method]
[Granule-accumulation in VERO cells used for determination of antitoxin titration by micro cell culture method: II. Nature of granules and influence on the potency testing of diphtheria toxoid]
[Heparin-binding epidermal growth factor (HB-EGF): myth or reality?]
[Histochemical changes in kidney, liver, and spleen with diphtheria toxin poisoning]
[Histochemical changes in the adrenal cortex of the guinea pig after diphtheria toxin poisoning]
[Histologic studies of the central nervous system in guinea pigs poisoned with diphtheria toxin]
[Identification of heterologous antitoxin in sera of patients with diphtheria]
[Immunity to diphtheria in advanced cancer patients]
[Immunity to diphtheria toxin in Israel in comparison with other subtropical countries. I.]
[Immunity to diphtheria toxin in Israel in comparison with other tropical countries. II. Statistical analysis.]
[Immunizing action of small doses of diphtheria toxin used in the Schick test]
[Immunochemical study of active fractions of diphtheria toxin and toxoid]
[Immunochromatographic and latex-agglutination systems for diphtheria toxin detection]
[Immunoelectrophoresis of purified diphtheria toxin.]
[Immunologic methods for the detection of diphtheria toxin (passive hemagglutination and ELISA for toxin detection in cultures and serum)]
[Immunological similarity of diphtheria toxin and EGF receptor]
[INCREASE OF THE FREE, SOLUBLE AND TOTAL ACTIVITY OF ACID PHOSPHATASE IN THE KIDNEYS OF GUINEA PIGS TREATED WITH DIPHTHERIA TOXIN.]
[Induction by dimethylnitrosamine of mutants resistant to diphtheria toxin in human cells]
[Infectious allergy. 3. The effect of desensitizing drugs on the course and outcome of infectious allergy caused by diphtheria toxin]
[Infectious allergy. XIV. Histochemical changes in redox enzymes in cells of the small intestine smooth muscle during sensitization with diphtheria exotoxin]
[Influence of cortisone on experimental diphtherial intoxication and on necrotic skin lesions due to diphtheria toxin in the guinea pig.]
[Influence of placental ischemia on the aggravation of renal changes previously induced with diphtheria toxin]
[Information from a study of the nature of secondary immunodeficient states. II. Effect of destruction of dorsal hippocampus structures on the intensity of signs of adjuvant arthritis in rats and cutaneous reactions to diphtheria toxin in rabbits]
[Inhibition of diphtheria toxin by salmine.]
[Interaction of diphtheria toxin B subunit with sensitive and insensitive mammalian cells].
[Interactions between Diphtheria toxin and dextran blue]
[Interference of diphtheria toxin and vitamin E observable in muscle lesions.]
[Inventive activity of the Department of Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine].
[INVESTIGATIONS OF THE HORMONE CONTENT OF THE ADRENAL GLANDS OF GUINEA PIGS POISONED WITH DIPHTHERIA TOXIN AND TREATED WITH STEROIDS.]
[Iron storage in tissue culture and its effect on the action of diphtheria toxin and poliomyelitis virus]
[Isoenzymes of transferases in serum from diphtheria patients]
[Isolation of peptides obtained by the action of cyanogen bromide on fragment A of diphtheria toxin]
[Isolation of trypsic and chymotrypsic peptides from fragment B of diphtheria toxin (proceedings)]
[Lipid metabolism of the liver in normal guinea pigs and after diphtheria toxin poisoning.]
[Mathematical model of the infection process in diphtheria for determining the therapeutic dose of antitoxic anti-diphtheria serum]
[Method of obtaining highly purified diphtheria toxin]
[Methods of labeling of diphtheria toxin with I-131 for biological applications. Preliminary note.]
[Microtiter enzyme-linked immunosorbent assay for diphtheria antitoxin in human sera--application of parallel line assay method]
[Minisatellite instability induced by okadaic acid]
[Mitogenic responsiveness to growth factor and tumor promoters and regulation of cell growth]
[Modification of beta-glucuronidase, leucine aminopeptidase and alkaline phosphatase activities by diphtheria toxin in experimental animals]
[Molecular chaperones facilitate soluble expression of recombinant non-toxic mutant CRM197 of diphtheria toxin in Escherichia coli].
[Molecular cloning and study of the expression of a region of a diphtheria toxin gene encoding fragment A of the Streptomyces lividans 66 strain]
[Monoclonal antibodies labeled with colloidal gold for immunochromatographic express analysis of diphtheria toxin].
[Morphologic reflection of protein biosynthesis disorders in the myocardial cells of rabbits with acute diphtheritic intoxication]
[Mycoplasma infection as a possible cause of hybridoma instability]
[Myocardial architectonic changes and cardiomyocytic apoptosis in the course of experimental diphtheria intoxication]
[Myosin and diphtheria toxin.]
[Neutralizing properties and antibody affinity specific to different portions of the diphtheria toxin molecule]
[Novel treatment modalities in cutaneous T cell lymphoma. Biologic response modifiers]
[Nuclear magnitude as an indication of the functional relation of hypophysis and adrenal cortex; physiologic adaptation reaction and toxic lesions of the cortex due to diphtheria toxin.]
[Nucleotide binding of diphtheria toxin and its fragment A]
[Occurrence of diphtheria toxin in saliva of patients (pathogenesis of diphtheria).]
[ON CHANGES IN THE SODIUM AND POTASSIUM IN INDIVIDUAL HEART AREAS AFTER DAMAGE WITH QUININE AND DIPHTHERIA TOXIN AND AFTER TREATMENT WITH G-STROPHANTHIN IN VIVO.]
[On criteria for the assessment of the biological activity of reactor diphtheria toxin]
[On the detoxification function of iron uptake: animal experiment studies on the detoxification of botulism A, tetanus and diphtheria toxin by hemosiderin and reducing substances. I.]
[On the effect of many substances on the flocculation time of diphtheria toxin and anatoxin.]
[On the effects of glucuronic acid preparations and various drugs on the formation of antibodies to diphtheria toxin.]
[On the mechanism of action of diphtheria toxin]
[On the purification of diphtheria toxin.]
[On the similarity of the molecular weights of the diphtheria toxin and anatoxin according to data of gel-filtration]
[Participation of thyroid hormones in realization of the action of diphtheria toxin on oxidative phosphorylation in rabbit liver mitochondria]
[Peptide maps of fragment A of diphtheria toxin. Application to the case of chemical modifications to tryptophan residues]
[Perspectives of application of recombinant diphtheria toxin derivatives].
[Phenolic hydroxyls and biological activity of diphtheria toxin.]
[PMNDTR mice: a new model to study neutrophils in vivo].
[Point mutations in tox promoter/operator and diphtheria toxin repressor (DTXR) gene associated with the level of toxin production by Corynebacterium diphtheriae strains isolated in Belarus]
[Polymorphism of tox and dtxR genes in circulating strains of Corynebacterium diphtheriae]
[Preliminary electron microscopic and x-ray study of the crystalline protein of diphtheria toxin]
[Preliminary studies of the effect of vitamin E on the succinoxidase system of the liver and on a possible interference with diphtheria toxin.]
[Preliminary study on the use of ELISA (microtechnic) in detecting antibodies to diphtheria toxin as compared with Schick test]
[PREPARATION OF PURE CRYSTALLIZED DIPHTHERIA TOXIN FROM CULTURES IN FERMENTOR. CHARACTERISTICS OF THE PURE TOXIN.]
[Presence of an amphipatic segment in the B fragment of diphtheria toxin (proceedings)]
[Primary structure of fragment A of diphtheria toxin. Tryptic peptides]
[Primary structure of fragment B of diphtheria toxin: N-terminal residues and alignment of the CNBr peptides]
[Primary structure of fragment B of diphtheria toxin: peptides obtained by cleavage by cyanogen bromide]
[Proceedings: Biological activity of diphtheria toxin fragment B]
[Proceedings: Chemical modification of arginyl residues of diphtheria toxin and its fragment a]
[Proceedings: Determination of tryptophan in the active center of diphtheria toxin]
[Proceedings: Tryptic cleavage of citraconylated of fragment b of diphtheria toxin]
[Production and characteristics of monoclonal antibodies to the diphtheria toxin]
[Production of diphtheria toxin on semisynthetic media with casein hydrolysate.]
[Promoting action of tetradecanoylphorbol acetate on the phenotypic expression of the mutation for the acquisition of resistance to diphtheria toxin in cultured human cells]
[Protective effect of cortisone on adrenals of guinea pigs intoxicated with diphtheria toxin; preliminary research.]
[Protective reaction of the myocardium in poisoning]
[PURIFICATION OF DIPHTHERIA TOXIN BY THE GEL FILTRATION METHOD.]
[Purification of diphtheria toxin: qualitative control of the fractions by the method of specific gel precipitation.]
[Quantitative determination of the tryptophan residues modified by 2-hydroxy-5-nitrobenzyl bromide by mercaptoethane sulfonic acid hydrolysis. Application to diphtheria toxin]
[Quantitative study of the reaction between diphtheria toxin & various antidiphtheria serums of low neutralizing capacity.]
[Recombinant fluorescent models for studying of diphtheria toxin].
[Relation of the toxic and immunizing effect of diphtheria toxin with respect to its administration.]
[Relationship between the molecular biology of diphtheria toxin and the problem of the mechanism of action of toxic proteins]
[Remote reactions in children to injections of adsorbed purified diphtheria toxin.]
[Results of muscle biopsies in diphtheritic polyneuropathy. Light- and electron-microscopic examinations of muscle fibers, intramuscular nerves, motor endplates, and intramuscular vessels]
[Role of the nervous system in immunity. V. Effect of neurotomy to sensitivity of the skin to diphtheria toxin.]
[Role of thyroid hormones in the mechanism of the uncoupling effect of diphtheria toxin]
[Sensitivity of some cell cultures to diphtheria toxin]
[SOME IMMUNOLOGICAL PROBLEMS IN INFANTS. I. NEUTRALIZING EFFECTS OF PRESENSITIZED LYMPHOCYTES ON DIPHTHERIA TOXIN.]
[Sources of error caused by toxin in Römer-Jensen's diphtheria toxin titration.]
[Specific and aspecific effect of diphtheria toxin and other bacterial toxins in etiology of local pathological manifestations.]
[Specific inhibiting action of diphtheria toxin on protein synthesis in monkey kidney cells in primary culture in vitro]
[Specificity of antibodies to diphtheria toxin subunits in children with various forms of diphtheria infections]
[Stability and virus-inhibiting effect of recombinant receptor toxins based on the human CD4 receptor and diphtheria toxin]
[Stability of diphtheria toxin used in Schick test.]
[Structure and function of diphtheria toxin]
[Studies on detoxication of diphteria toxin by adrenal and pituitary hormones. (2). Effects on the paralytic dose of diphtheria toxin]
[Studies on detoxication of diphtheria toxin by adrenal and pituitary hormones. (1). Effects on the lethal dose of diphtheria toxin]
[Studies on mutual influence of diphtheria toxin and vitamin B 12 in the culture of guinea pig fetal cells]
[Studies on the mechanism of action of diphtheria toxin]
[Studies on the Seemueller phenomenon. III. Serological demonstration of intravital fixation of hemagglutinins and hemolysins by diphtheria toxin.]
[STUDIES ON THE SURFACE STRUCTURE AND CHEMICAL COMPOSITION OF DIPHTHERIA TOXIN AND TOXOID. I. BINDING OF COPPER IONS BY PURIFIED DIPHTHERIA TOXIN AND TOXOID.]
[Studies on the toxic action of diphtheria toxin on mammalian cells. 2. On the mitochondrial oxidative phosphorylation uncoupling of a product of Corynebacterium diphtheriae metabolism.]
[Studies on the toxoid production from diphtheria toxin by sodium glucuronate. 1. On the effect of sodium glucuronate on the toxicity of diphtheria toxin.]
[Studies on the toxoid production from diphtheria toxin by sodium glucuronate. 2. On the antigenicity of glucuronate toxoid.]
[Study of diphtheria anatoxins in immunochemical and tissue culture assays]
[Study of diphtheria toxin and antitoxin. II. Preparation of antitoxin using immunosorbents on the basis of highly purified antigens]
[Study of diphtheria toxin fragments using circular dichroism (proceedings)]
[Study of immune phenomena by means of tissue culture. VIII. Titration of diphtheria toxin and antitoxin.]
[Study of immunological phenomena by means of tissue cultures. II. Cytopathogenic action of diphtheria toxin.]
[STUDY OF SOME METABOLIC PROCESSES OF THE FAILING HEART IN EXPERIMENTAL CONDITIONS. V. DYNAMIC FOLLOW-UP OF CHANGES IN WATER AND ELECTROLYTE METABOLISM FOLLOWING ADMINISTRATION OF DIPHTHERIA TOXIN.]
[Study of the chemical receptor for diphtheria toxin in cell membranes]
[Study of the construction and function of an eukaryotic expression plasmid of immunotoxin DT390 gene]
[Study on the mechanism of detoxification of protein toxins by formol. I. Incorporation of free radioactive lysine in pure diphtheria toxin in the presence of formol (irreversible detoxification)]
[Study on the mechanism of production of diphtheria toxin.]
[Suspected diphtheria. Immediately start therapy!]
[Synthesis, secretion, and proteolytic degradation of diphtheria toxin in Escherichia coli]
[Targeted intracellular site-specific drug delivery: photosensitizer targeting to melanoma cell nuclei]
[Technic of demonstrating diphtheria toxin by plate test.]
[Temperature reaction and oxidative phosphorylation in the liver during intravenous and intracerebral administration of diphtheria toxin]
[The antiviral action of recombinant receptorotoxins based on the diphtheria toxin and the human T-lymphocyte CD4-receptor]
[The binding of diphtheria toxin and human A-anti B serum; contribution to the Seemüller's observations.]
[The biology of aerobic bacteria in the fertilized chicken egg. I. Culture of Corynebacterium diphtheriae and the effects of diphtheria toxin on the fertilized chick embryo.]
[The coagglutination reaction for detecting diphtheria toxin]
[The determination of diphtheria toxin in circulating immune complexes]
[The diagnostic effectiveness of an immunoenzyme test system for determining diphtheria toxin antigens in the blood serum in a clinical laboratory trial]
[The discovery of diphtheria toxin and its consequences; homage to Emile Roux.]
[The effect of a detoxifying substance from eucalyptus leaves on the amino acid composition of diphtheria toxin]
[The effect of diphtheria toxin on chorionic gonadotropin]
[The effect of diphtheria toxin on proliferation of a transplantable culture of human amnion cells]
[The effect of neuraminidase of C. diphtheriae on the functional capacity of the peritoneal exudate cells of guinea pigs to diphtheria bacilli]
[The effect of transplantation of bone marrow or lymphocytes on resistance of irradiated animals to diphtheria toxin.]
[The enhancement of cell resistance against diphtheria toxin under the influence of latent viral infection]
[The estimation of the amount of diphtheria toxin and its activity by various tests in the dynamic cultivation of Corynebacterium diphtheriae PW8]
[THE IMMUNIZING EFFECT OF SMALL DOSES OF DIPHTHERIA TOXIN DURING THE SCHICK TEST.]
[The influence of culture conditions on deoxyribonuclease formation by diphtheria bacteria]
[The infrared spectra and optical rotatory dispersion in preparations of diphtheria toxin and anatoxin]
[The interrelationship of biomass and toxin accumulation to the dynamics of the physicochemical parameters of Corynebacterium diphtheriae PW8 cultivation]
[The local manifestations of diphtheria]
[The problem history of the toxin-antitoxin theory in medical microbiology]
[The protective effect of the nerve growth factor in exposing a nerve tissue culture to diphtheria toxin]
[The protective effect of the nerve growth factor on sensory neurons in organotypic culture under the action of diphtheria toxin]
[The relation of alkaline plasma phosphatase to pituitary-adrenocortical system as studied on guinea pig treated with diphtheria toxin.]
[The research on construction and expression of eukaryotic expression plasmid for a recombinant immunotoxin mMIP-1alpha-DT390]
[The respiratory pigments of the myocardium in experimental poisoning with diphtheria toxin.]
[The risk of pertussis and diphtheria infections among pediatric healthcare workers in Japan]
[The role of donor cells and antibodies in the resistance of animals--radiation chimeras to diphtheria toxin]
[The role of somatosensory afferents in neuroimmune reactions during exposure to diphtheria toxin]
[The species C. diphtheriae]
[The spleen and the visceral lesions of diphtheria toxin.]
[The structural-functional organization of the diphtheria toxin]
[The use of monoclonal antibodies for the determination of diphtheria toxin and its components]
[Therapeutic effects of KCl and MgCl2 in acute poisoning with diphtheria toxin in guinea pigs.]
[Titration of a diphtheria toxin in tissue culture. II. Titration of a diphtheria toxin according to its cytopathic activity]
[Titration of diphtheria toxin and antitoxin on the basis of the cytopathic effect in the BSC-1 cell culture]
[Titration of diphtheria toxin and antitoxin with the metabolic pH color test and cells of the BSC-1 line]
[Toxin-neutralizing properties of antibodies to diphtheria toxin recombinant subunits A and B and a new method of their estimation]
[Treating diphtheria in the 21st century].
[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
[Use of cell cultures for dynamic studies on diphtheria toxin formation]
[Use of muramyl dipeptides in models of synthetic vaccines]
[Use of the passive hemagglutination inhibition test to measure diphtheria toxin activity]
[Use of the viroimmunotest for the quantitative determination of diphtheria toxin]
[Variants in the immune response to revaccination with diphtheria anatoxin in adults]
[Variations in the electrophoretic patterns of the serum of the rat treated with diphtheria toxin.]
[Virioimmunoassay for studying the interaction of diphtheria toxin with cell membranes]
Disseminated Intravascular Coagulation
High lactoferrin levels in disseminated intravascular coagulation and its possible negative role in coagulation.
Distemper
Ultrastructural features of viral leukoencephalomyelitis of goats.
Diverticular Diseases
Combined therapy: rifaximin-? and arabinogalactan with lactoferrin combination effectively prevents recurrences of symptomatic uncomplicated diverticular disease.
DNA Virus Infections
Highlights in the development of new antiviral agents.
Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo.
Down Syndrome
DNA polymerase activity as an index of lymphocyte stimulation: studies in Down's syndrome.
Loss of DNA polymerase ? induces cellular senescence.
Overexpression of DNAse I in brain of patients with Down syndrome.
Drug Hypersensitivity
Assessment of preferential cleavage of an actively transcribed retroviral hybrid gene in murine cells by deoxyribonuclease I, bleomycin, neocarzinostatin, or ionizing radiation.
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
Dry Eye Syndromes
A novel and innovative paper-based analytical device for assessing tear lactoferrin of dry eye patients.
A novel fluorescent lipid probe for dry eye: retrieval by tear lipocalin in humans.
A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease.
Abnormal protein profiles in tears with dry eye syndrome.
Age-Related Dry Eye Lactoferrin and Lactobionic Acid.
Anti-DNase I Antibody: A New Serological Reactivity in Primary Sjögren Syndrome.
Association of dry eye signs and symptoms with tear lactoferrin concentration.
Bacteriology and tear protein profiles of the dry eye.
Decreased tear lactoferrin concentration in patients with chronic hepatitis C.
Dietary Supplementation with a Combination of Lactoferrin, Fish Oil, and Enterococcus faecium WB2000 for Treating Dry Eye: A Rat Model and Human Clinical Study.
Effect of Oral Lactoferrin on Cataract Surgery Induced Dry Eye: A Randomised Controlled Trial.
Identification of Tear Fluid Biomarkers in Dry Eye Syndrome Using iTRAQ Quantitative Proteomics.
Influence of Ophthalmic Solutions on Tear Components.
Influence of topical anesthesia on tests diagnostic of blepharitis-associated dry eye syndrome.
Label-Free Detection of Tear Biomarkers Using Hydrogel-Coated Gold Nanoshells in a Localized Surface Plasmon Resonance-Based Biosensor.
Lactoferrin Has a Therapeutic Effect via HIF Inhibition in a Murine Model of Choroidal Neovascularization.
Lactoferrin suppresses loss of corneal epithelial integrity in a rabbit short-term dry eye model.
Minor Salivary Gland Transplantation for Severe Dry Eyes.
Ocular surface damage and tear lactoferrin in dry eye syndrome.
Selenium-binding lactoferrin is taken into corneal epithelial cells by a receptor and prevents corneal damage in dry eye model animals.
Single Nucleotide Polymorphisms in the BDNF, VDR, and DNASE 1 Genes in Dry Eye Disease Patients: A Case-Control Study.
Tear fluid extracellular DNA: diagnostic and therapeutic implications in dry eye disease.
Tear Lactoferrin and Features of Ocular Allergy in Different Severities of Meibomian Gland Dysfunction.
Tear lactoferrin levels and ocular bacterial flora in HIV positive patients.
Tear lipocalin and lysozyme in Sjögren and non-Sjögren dry eye.
Tear lipocalin captures exogenous lipid from abnormal corneal surfaces.
The effect of punctal occlusion on tear lactoferrin in aqueous deficient dry eye patients.
The European Community Study Group on diagnostic criteria for Sjögren's syndrome. Sensitivity and specificity of tests for ocular and oral involvement in Sjögren's syndrome.
Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections.
[Dry eye syndrome of deficient lacrima production treated with the acupoint thread-embedding therapy: a randomized controlled trial].
[Effects of acupuncture on lactoferrin content in tears and tear secretion in patients suffering from dry eyes: a randomized controlled trial].
[Progression of research for the association between sex hormones and dry eye].
Dysentery
Approach to the patient with infectious colitis.
Colicin types of Shigella sonnei isolated from epidemics of dysentery in Aichi prefecture of Japan.
Investigation on the relation between colicin types of isolated strains of Shigella sonnei and epidemics of dysentery when the strains of serotypes of Escherichia coli were used as indicator strains.
Investigation on the relation between colicin types of isolated strains of Shigella sonnei and epidemics of dysentery.
To shigellosis epidemicity in East-Slovakian region.
[Colicin as a factor of Escherichia and the Shigella antagonism during dysentery infection. I. Preparation of apurified colicin V preparation and study of its activity]
[Colicin-sensitivity of Flexner and Sonne dysentery bacteria and the practical value of a method of determining their colicin sensitivity]
[The importance of colicin typing in the epidemiologic analysis of illnesses with colenteritis and Sonne dysentery]
Dysentery, Amebic
Oral lactoferrin treatment resolves amoebic intracecal infection in C3H/HeJ mice.
Dysentery, Bacillary
A survey of colicin types and phage types of Shigella sonnei in Czechoslovakia 1976-1978.
Glycoconjugation of Shigella flexneri type 2a O-polysaccharide with CRM197 as a potential vaccine candidate for shigellosis.
Innate immune responses in children and adults with Shigellosis.
Protective role of human lactoferrin against invasion of Shigella flexneri M90T.
[Epidemiology of shigellosis and colicin typing of Shigella sonnei. A 14-year study]
Dyslipidemias
Association of circulating lactoferrin concentration and 2 nonsynonymous LTF gene polymorphisms with dyslipidemia in men depends on glucose-tolerance status.
Echinococcosis
Deoxyribonuclease activity in Echinococcus granulosus protoscoleces and hydatid fluid.
Echovirus Infections
Bovine lactoferrin inhibits echovirus endocytic pathway by interacting with viral structural polypeptides.
Bovine lactoferrin peptidic fragments involved in inhibition of Echovirus 6 in vitro infection.
Eclampsia
[The regulatory transport proteins in diagnostic and prognosis of preeclampsia].
Ecthyma, Contagious
Lentivirus expressing shRNAs inhibit the replication of contagious ecthyma virus by targeting DNA polymerase gene.
Ectromelia
Orthopoxvirus DNA: a comparison of restriction profiles and maps.
Ectropion
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Eczema
Plasma lactoferrin reflects neutrophil activation in psoriasis.
[DNAase in the complex treatment of Kaposi's herpetiform eczema]
Ehrlichiosis
Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection.
Elephantiasis, Filarial
Lack of IgG4 antibody response to carbohydrate antigens in patients with lymphatic filariasis.
Embryo Loss
Comparison of the intravenous chicken challenge method with the embryo lethality assay for studies in avian colibacillosis.
Empyema
A combined intrapleural administration of dornase alfa and tissue plasminogen activator is safe in children with empyema - A pilot study.
Alteplase and DNase for the treatment of pleural empyema in rats.
Asymptomatic man with an incidental finding of a massive empyema.
Cost-Effectiveness Analysis of Fibrinolysis vs Thoracoscopic Decortication for Early Empyema.
Effects of streptokinase and deoxyribonuclease on viscosity of human surgical and empyema pus.
Intrapleural Dornase and Tissue Plasminogen Activator in pediatric empyema (DTPA): a study protocol for a randomized controlled trial.
Mixing It Up: Coadministration of tPA/DNase in Complicated Parapneumonic Pleural Effusions and Empyema.
Parafalcine subdural empyema: The unresolved controversy over the need for surgical treatment.
Parapneumonic Effusions Are Characterized by Elevated Levels of Neutrophil Extracellular Traps.
Rethinking the Doses of Tissue Plasminogen Activator and Deoxyribonuclease Administrated Concurrently for Intrapleural Therapy for Complicated Pleural Effusion and Empyema.
Sequential intrapleural administration of fibrinolytic drugs and dornase alfa for empyema management. Treatment protocol based on its physicochemical stability.
Successful treatment of empyema thoracis with human recombinant deoxyribonuclease.
Tissue plasminogen activator combined with human recombinant deoxyribonuclease is effective therapy for empyema in a rabbit model.
Two sequential tPA/DNase courses for noncommunicating loculated collections in pleural infection.
Use of fibrinolytics and deoxyribonuclease in adult patients with pleural empyema: a consensus statement.
[Decortication of the lung and resection of the cavity in the treatment of chronic empyema; review of cases treated by other methods and use of streptodornase and streptokinase in coagulated hemothorax.]
[Streptokinase and streptodornase therapy of empyema and postoperative hemothorax.]
Empyema, Pleural
Effectiveness of Intrapleural Tissue Plasminogen Activator and Dornase Alfa vs Tissue Plasminogen Activator Alone in Children with Pleural Empyema: A Randomized Clinical Trial.
Intrapleural administration of DNase alone for pleural empyema.
New therapy of pleural empyema by deoxyribonuclease.
Use of fibrinolytics and deoxyribonuclease in adult patients with pleural empyema: a consensus statement.
[Intrapleural use of streptokinase and streptodornase in postoperative pleural empyema.]
[Streptokinase and streptodornase (distreptase) in the treatment of tuberculous pleural empyemas.]
[Treatment of pleural empyema with streptokinase and streptodornase.]
[Use of trypsin, streptokinase, and streptodornase in thoracic empyema.]
Encephalitis
Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.
Fatal human herpesvirus type 1 infection in a white-handed gibbon (Hylobates lar).
Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice.
Pre-clinical and Clinical Implications of "Inside-Out" vs. "Outside-In" Paradigms in Multiple Sclerosis Etiopathogenesis.
Varicella-zoster vasculitis presenting with cerebellar hemorrhage.
Encephalitis, Japanese
Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein.
Gateways to clinical trials.
Encephalitis, Tick-Borne
[Lactoferrin and its role in the pathogenesis of tick-borne encephalitis]
Encephalomyelitis
Immunoregulatory function of lactoferrin in immunosuppressed and autoimmune animals.
Lactoferrin ameliorates symptoms of experimental encephalomyelitis in Lewis rats.
Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice.
Pre-clinical and Clinical Implications of "Inside-Out" vs. "Outside-In" Paradigms in Multiple Sclerosis Etiopathogenesis.
Ultrastructural features of viral leukoencephalomyelitis of goats.
Encephalomyelitis, Autoimmune, Experimental
Demyelination and remyelination in the rat central nervous system following ethidium bromide injection.
Pre-clinical and Clinical Implications of "Inside-Out" vs. "Outside-In" Paradigms in Multiple Sclerosis Etiopathogenesis.
Ultrastructural features of viral leukoencephalomyelitis of goats.
Encephalomyelitis, Equine
Hospitalized Children With Encephalitis in the United States: A Pediatric Health Information System Database Study.
Encephalomyelitis, Western Equine
Inhibition of DNA synthesis in BHK cells infected with western equine encephalitis virus. 1. Induction of an inhibitory factor of cellular DNA polymerase activity.
Inhibition of DNA synthesis in BHK cells infected with western equine encephalitis virus. 2. Properties of the inhibitory factor of DNA polymerase induced in infected cells.
Endocarditis
Culture-negative endocarditis diagnosed using 16S DNA polymerase chain reaction.
Neutrophil Extracellular Traps Enhance Staphylococcus Aureus Vegetation Formation through Interaction with Platelets in Infective Endocarditis.
Endometrial Hyperplasia
Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.
Endometrial Neoplasms
Bovine lactoferrin and lactoferrin peptides affect endometrial and cervical cancer cell lines.
Characterization of estrogen-responsive mouse lactoferrin promoter.
Clinicopathological characteristics of POLE mutation in patients with non-small-cell lung cancer.
DNA polymerase {epsilon} and ? exonuclease domain mutations in endometrial cancer.
Estrogen regulation of lactoferrin expression in human endometrium.
Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin upstream promoter transcription factor and estrogen receptor-binding elements.
Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter.
Genetics of endometrial cancer.
Genomic characterization of five commonly used endometrial cancer cell lines.
Human estrogen receptor-like 1 (ESRL1) gene: genomic organization, chromosomal localization, and promoter characterization.
Human Pol ?-dependent replication errors and the influence of mismatch repair on their correction.
Identification of the estrogen sensitive marker in human endometrial carcinoma RL95-2 cells.
Isolation and characterization of a gene encoding human Kruppel-like factor 5 (IKLF): binding to the CAAT/GT box of the mouse lactoferrin gene promoter.
Lactoferrin gene promoter in human and mouse. Analogous and dissimilar characteristics.
Lactoferrin immunoexpression in endometrial carcinomas: relationships with sex steroid hormone receptors (ER and PR), proliferation indices (Ki-67 and AgNOR) and survival.
Lactoferrin: a tamoxifen-responsive protein in normal and malignant human endometrial cells in culture.
Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element.
p53, Mismatch Repair Protein, and POLE Abnormalities in Ovarian Clear Cell Carcinoma: An Outcome-based Clinicopathologic Analysis.
Polymerase ? (POLE) mutations in endometrial cancer: clinical outcomes and implications for Lynch syndrome testing.
The mouse estrogen receptor-related orphan receptor alpha 1: molecular cloning and estrogen responsiveness.
Tumor Mutational Burden Guides Therapy in a Treatment Refractory
Endometriosis
CD206+?macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model.
Decreased lactoferrin levels in peritoneal fluid of women with minimal endometriosis.
Inflammatory markers in endometriosis: reduced peritoneal neutrophil response in minimal endometriosis.
The development of endometriosis in a murine model is dependent on the presence of dendritic cells.
The M2a macrophage subset may be critically involved in the fibrogenesis of endometriosis in mice.
Endometritis
DNaseI protects lipopolysaccharide-induced endometritis in mice by inhibiting neutrophil extracellular traps formation.
Lactoferrin expression in the horse endometrium: Relevance in persisting mating-induced endometritis.
Lactoferrin suppresses lipopolysaccharide-induced endometritis in mice via down-regulation of the NF-?B pathway.
The anti-inflammatory effect of exogenous lactoferrin on breeding-induced endometritis when administered post-breeding in susceptible mares.
The effect of select seminal plasma proteins on endometrial mRNA cytokine expression in mares susceptible to persistent mating-induced endometritis.
Endophthalmitis
Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin.
Endotoxemia
Early fall of circulating iron and rapid rise of lactoferrin in septicemia and endotoxemia: an early defence mechanism.
ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels.
Lactoferrin as an indicator of septicemia and endotoxemia in pigs.
Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model.
Lactoferrin protects gut mucosal integrity during endotoxemia induced by lipopolysaccharide in mice.
Lethality in LPS-induced endotoxemia in C3H/HeCr mice is associated with prevalence of proinflammatory cytokines: lack of protective action of lactoferrin.
Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.
Nutritional Management of Metabolic Endotoxemia: A Clinical Review.
Enteritis
Characterization of Escherichia coli serogroups causing meningitis, sepsis and enteritis. II. Classification of Escherichia coli O78 strains by phage sensitivity, colicin type and antibiotic resistance.
Development of nested polymerase chain reaction-based diagnosis of duck enteritis virus and detection of DNA polymerase gene from non-descriptive duck breeds of West Bengal, India.
Full genome analysis of a novel adenovirus from the South Polar skua (Catharacta maccormicki) in Antarctica.
Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis.
Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis.
Study of Escherichia coli O114 associated with a hospital outbreak.
Enterocolitis
ELFIN, the United Kingdom preterm lactoferrin trial: interpretation and future questions.
Summary Protocol for a Multi-Centre Randomised Controlled Trial of Enteral Lactoferrin Supplementation in Newborn Very Preterm Infants (ELFIN).
The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial.
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
[Colicin sensitivity of enteropathogenic and banal Escherichia isolated from children with enterocolitis]
Enterocolitis, Necrotizing
Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial.
Can lactoferrin prevent neonatal sepsis and necrotizing enterocolitis?
Commentary on "Enteral Lactoferrin Supplementation for Prevention of Sepsis and Necrotizing Enterocolitis in Preterm Infants".
Dose Escalation Study of Bovine Lactoferrin in Preterm Infants: Getting the Dose Right.
Early optimal nutrition improves neurodevelopmental outcomes for very preterm infants.
Enteral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
Evidence from systematic reviews of randomized trials on enteral lactoferrin supplementation in preterm neonates.
Exposure to Gastric Acid Inhibitors Increases the Risk of Infection in Preterm Very Low Birth Weight Infants but Concomitant Administration of Lactoferrin Counteracts This Effect.
Is Mother's Own Milk Lactoferrin Intake Associated with Reduced Neonatal Sepsis, Necrotizing Enterocolitis, and Death?
Lactoferrin and necrotizing enterocolitis.
Lactoferrin and Neonatology- Role in neonatal sepsis and necrotizing enterocolitis: Present, past and future.
Lactoferrin for prevention of neonatal infections.
Lactoferrin Reduces Necrotizing Enterocolitis Severity by Upregulating Intestinal Epithelial Proliferation.
Lactoferrin Supplementation to Prevent Late-Onset Sepsis in Preterm Infants: A Meta-Analysis.
Lactoferrin-enhanced anoikis: a defense against neonatal necrotizing enterocolitis.
Lactoferrin: A Critical Player in Neonatal Host Defense.
Mother's milk, feeding strategies, and lactoferrin to prevent necrotizing enterocolitis.
Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants.
Oral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Oral Lactoferrin to Prevent Nosocomial Sepsis and Necrotizing Enterocolitis of Premature Neonates and Effect on T-Regulatory Cells.
Prophylactic lactoferrin for preventing late-onset sepsis and necrotizing enterocolitis in preterm infants: A PRISMA-compliant systematic review and meta-analysis.
Protective effects of lactoferrin on injured intestinal epithelial cells.
Reduction in necrotizing enterocolitis and improved outcomes in preterm infants following routine supplementation with Lactobacillus GG in combination with bovine lactoferrin.
Role of Lactoferrin in Neonates and Infants: An Update.
Small intestinal lactoferrin and calprotectin levels in different stages of necrotizing enterocolitis in a rat model.
Synbiotic use for the prevention of sepsis and necrotizing enterocolitis in very low birth weight neonates: a randomized controlled trial.
The impact of probiotics and lactoferrin supplementation on piglet gastrointestinal microbial communities.
The role of fecal calprotectin and lactoferrin in the diagnosis of necrotizing enterocolitis.
The Role of Lactoferrin in Gastrointestinal and Immune Development and Function: A Preclinical Perspective.
[Lactoferrin - a glycoprotein of great therapeutic potentials].
[Recent advances in prevention of sepsis in the preterm neonate].
Entropion
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Enzootic Bovine Leukosis
Antitumor effect of diphtheria toxin A-chain gene-containing cationic liposomes conjugated with monoclonal antibody directed to tumor-associated antigen of bovine leukemia cells.
Characterization of the RNA dependent DNA polymerase of bovine leukemia virus.
Evaluation of cationic liposomes for delivery of diphtheria toxin A-chain gene to cells infected with bovine leukemia virus.
Growth inhibition of cancer cells by co-transfection of diphtheria toxin A-chain gene plasmid with bovine leukemia virus-tax expression vector.
In vivo antitumor effect of cationic liposomes containing diphtheria toxin A-chain gene on cells infected with bovine leukemia virus.
Purification and characterization of bovine leukemia virus DNA polymerase.
Suggestive evidence for an oncorna-virus-specific DNA polymerase from C-type particles of bovine leukosis.
Suppressive effect of liposomes containing DNA coding for diphtheria toxin A-chain on cells transformed with bovine leukemia virus.
Eosinophilia
Cytoplasmic labelling of eosinophils with tritiated thymidine triphosphate.
[The Churg-Strauss syndrome]
Epididymitis
[The immunochemical determination of the concentration of organ-specific ejaculate proteins in the differential diagnosis of chronic inflammatory diseases of the male reproductive system]
Epilepsy
Febrile infection-related epilepsy syndrome (FIRES) is not caused by SCN1A, POLG, PCDH19 mutations or rare copy number variations.
Global characterization of copy number variants in epilepsy patients from whole genome sequencing.
Epstein-Barr Virus Infections
Activation of the Epstein-Barr virus DNA polymerase promoter by the BRLF1 immediate-early protein is mediated through USF and E2F.
Effects of Epstein-Barr Virus Infection on the Risk and Prognosis of Primary Laryngeal Squamous Cell Carcinoma: A Hospital-Based Case-Control Study in Taiwan.
Identification of tear lipocalin as a novel autoantigen target in Sjögren's syndrome.
Induction of lytic Epstein-Barr virus (EBV) infection in EBV-associated malignancies using adenovirus vectors in vitro and in vivo.
Inhibition of Epstein-Barr virus infection by lactoferrin.
Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(a)-binding protein are distinct processes mediated by two epstein barr virus proteins.
Equine Infectious Anemia
Involvement of C-terminal structural elements of equine infectious anemia virus reverse transcriptase in DNA polymerase and ribonuclease H activities.
Mechanism of inhibition of HIV reverse transcriptase by toxiusol, a novel general inhibitor of retroviral and cellular DNA polymerases.
Erythema
Acute skin eruptions that are positive for herpes simplex virus DNA polymerase in patients with stem cell transplantation: a new manifestation within the erythema multiforme reactive dermatoses.
United States Standard Diphtheria Toxin for the Schick Test and the Erythema Potency Assay for the Schick Test Dose.
United States standard diphtheria toxin for the Schick text and the erythema potency assay for the Schick text dose.
Erythema Induratum
Erythema induratum of Bazin as a tuberculid: confirmation of Mycobacterium tuberculosis DNA polymerase chain reaction analysis.
Erythema Infectiosum
Detection of human parvovirus B19 infection in first-trimester fetal loss.
Erythema Multiforme
Acute skin eruptions that are positive for herpes simplex virus DNA polymerase in patients with stem cell transplantation: a new manifestation within the erythema multiforme reactive dermatoses.
Detection and genotyping of human herpes simplex viruses in cutaneous lesions of erythema multiforme by nested PCR.
Expression of herpes simplex virus DNA fragments located in epidermal keratinocytes and germinative cells is associated with the development of erythema multiforme lesions.
Herpes simplex virus associated erythema multiforme (HAEM) is mechanistically distinct from drug-induced erythema multiforme: interferon-gamma is expressed in HAEM lesions and tumor necrosis factor-alpha in drug-induced erythema multiforme lesions.
Escherichia coli Infections
Antibacterial and immunomodulatory effects of Pheromonicin-NM on Escherichia coli-challenged bovine mammary epithelial cells.
Changes in lactoferrin, immunoglobulin G, bovine serum albumin, and alpha-lactalbumin during acute experimental and natural coliform mastitis in cows.
Dietary Inclusion of Colicin E1 Is Effective in Preventing Postweaning Diarrhea Caused by F18-Positive Escherichia coli in Pigs.
Lactoferrin stimulates killing and clearance of bacteria but does not prevent mortality of diabetic mice.
Lactoferrin: an iron-binding antimicrobial protein against Escherichia coli infection.
Measurement of fecal lactoferrin for rapid diagnosis of enterohemorrhagic Escherichia coli infection.
Recombinant outer membrane protein A induces a protective immune response against Escherichia coli infection in mice.
Esophageal Neoplasms
G648C variant of DNA polymerase ? sensitizes esophageal cancer to chemotherapy.
MiR-149 sensitizes esophageal cancer cell lines to cisplatin by targeting DNA polymerase ?.
Overexpression of A613T and G462T variants of DNA polymerase ? weakens chemotherapy sensitivity in esophageal cancer cell lines.
Retraction Note: Overexpression of A613T and G462T variants of DNA polymerase ? weakens chemotherapy sensitivity in esophageal cancer cell lines.
The Combination of Two Bioactive Constituents, Lactoferrin and Linolenic Acid, Inhibits Mouse Xenograft Esophageal Tumor Growth by Downregulating Lithocholyltaurine and Inhibiting the JAK2/STAT3-Related Pathway.
[Immunochemical comparison of lactoferrin of human milk and lactoferrin of neutrophils]
[The superoxide theory of pathogenesis and therapy of immune disorders]
Esophageal Squamous Cell Carcinoma
DNA polymerase ? mutations and survival of patients with esophageal squamous cell carcinoma in Linzhou City, China.
DNA polymerase ? promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.
HAX-1 promotes the chemoresistance, invasion, and tumorigenicity of esophageal squamous carcinoma cells.
Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of ESCC.
REV3L, the catalytic subunit of DNA polymerase ?, is involved in the progression and chemoresistance of esophageal squamous cell carcinoma.
Esophagitis
Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity?
Protective effect of lactoferrin on acute acid reflux-induced esophageal mucosal damage.
Exanthema
Dornase alfa for cystic fibrosis.
Dornase alfa. A review of its pharmacological properties and therapeutic potential in cystic fibrosis.
Monogenic lupus due to DNASE1L3 deficiency in a pediatric patient with urticarial rash, hypocomplementemia, pulmonary hemorrhage, and immune-complex glomerulonephritis.
Exocrine Pancreatic Insufficiency
Lactoferrin and albumin in human pancreatic juice: a valuable test for diagnosis of pancreatic diseases.
exodeoxyribonuclease (lambda-induced) deficiency
Construction of a highly error-prone DNA polymerase for developing organelle mutation systems.
Eye Diseases
Analysis of human tear protein profiles using high performance liquid chromatography (HPLC).
Fanconi Anemia
Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells.
Correction of the DNA repair defect in Fanconi anemia complementation groups A and D cells.
Defective DNA endonuclease activities in Fanconi's anemia cells, complementation groups A and B.
Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals.
DNA polymerase ? compensates for Fanconi anemia pathway deficiency by countering DNA replication stress.
Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response.
Preliminary study on the function of the POLD1 (CDC2) EXON2 c.56G>A mutation.
The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.
Ubiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication.
Fatigue Syndrome, Chronic
Antibodies to Epstein-Barr virus-specific DNase and DNA polymerase in the chronic fatigue syndrome.
Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer.
Hormonal influences on stress-induced neutrophil mobilization in health and chronic fatigue syndrome.
Fatty Liver
Depression of interferon production in leukocytes of cows with fat mobilization syndrome.
Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis.
Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice.
Fetal Growth Retardation
Circulating cell-free DNA concentration and DNase I activity of peripheral blood plasma change in case of pregnancy with intrauterine growth restriction compared to normal pregnancy.
Nutritional Intervention for Developmental Brain Damage: Effects of Lactoferrin Supplementation in Hypocaloric Induced Intrauterine Growth Restriction Rat Pups.
Fibroadenoma
Relative value of oestrogen receptor assay, lactoferrin content, and glucose-6-phosphate dehydrogenase activity as prognostic indicators in primary breast cancer.
Fibroma
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Immunolocalization of lactoferrin in cartilage-forming neoplasms.
Fibroma, Ossifying
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Fibrosarcoma
Lactoferrin inhibits growth of malignant tumors of the head and neck.
The polyomavirus enhancer activates chromatin accessibility on integration into the HPRT gene.
Use of the Rad51 promoter for targeted anti-cancer therapy.
Focal Infection
Effect of Varidase (streptodornase) on biofilm formed by Pseudomonas aeruginosa.
Food Hypersensitivity
Is there any association between secretory IgA and lactoferrin concentration in mature human milk and food allergy in breastfed children.
Foot-and-Mouth Disease
OmpA-FMDV VP1 fusion proteins: production, cell surface exposure and immune responses to the major antigenic domain of foot-and-mouth disease virus.
One-tube and one-buffer system of RT-PCR amplification of 1D gene of foot-and-mouth disease virus field isolates.
[Use of muramyl dipeptides in models of synthetic vaccines]
Fowlpox
Identification by a random sequencing strategy of the fowlpoxvirus DNA polymerase gene, its nucleotide sequence and comparison with other viral DNA polymerases.
Friedreich Ataxia
Association between trinucleotide CAG repeats of the DNA polymerase gene (POLG) with age of onset of Iranian Friedreich's ataxia patients.
Fused Kidney
Midline signaling regulates kidney positioning but not nephrogenesis through Shh.
Galactorrhea
Composition of breast fluid of a man with galactorrhea and hyperprolactinaemia.
Gallbladder Neoplasms
Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer.
Gallstones
A radical view of gallstone aetiogenesis.
Gastritis
Effect of lactoferrin on Helicobacter felis induced gastritis.
Expression of lactoferrin in human stomach.
Gastric juice levels of lactoferrin and Helicobacter pylori infection.
Inhibition of Helicobacter pylori infection by bovine milk glycoconjugates in a BAlb/cA mouse model.
Recombinant human lactoferrin is effective in the treatment of Helicobacter felis-infected mice.
Use of lactoferrin for Helicobacter pylori eradication. Preliminary results.
Gastritis, Atrophic
Identification, characterization, and immunogenicity of the lactoferrin-binding protein from Helicobacter pylori.
Iron acquisition by Helicobacter pylori: importance of human lactoferrin.
Gastroenteritis
Antiviral Effects of Bovine Lactoferrin on Human Norovirus.
Discriminatory potential of C-reactive protein, cytokines, and fecal markers in infectious gastroenteritis in adults.
Effect of lactoferrin on enteric pathogens.
Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses.
Lactoferrin for prevention of common viral infections.
The Preventive Effect of Lactoferrin-Containing Yogurt on Gastroenteritis in Nursery School Children-Intervention Study for 15 Weeks.
Gastrointestinal Diseases
Age-related faecal calprotectin, lactoferrin and tumour M2-PK concentrations in healthy volunteers.
Clinical Significance of Inflammatory Biomarkers in Acute Pediatric Diarrhea.
Duodenal lactoferrin in patients with chronic pancreatitis and gastrointestinal diseases.
Immunochemical detection of human lactoferrin in feces as a new marker for inflammatory gastrointestinal disorders and colon cancer.
Lactoferrin in gastrointestinal disease.
Lactoferrin in pure pancreatic juice.
Potent antibacterial peptides generated by pepsin digestion of bovine lactoferrin.
The role of fecal calprotectin and lactoferrin in the diagnosis of necrotizing enterocolitis.
[Measurement of fecal lactoferrin for diagnosis on pediatric gastrointestinal disease]
Gastrointestinal Neoplasms
DNase1L3 suppresses hepatocellular carcinoma growth via inhibiting complement autocrine effect.
Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Genetic Diseases, Inborn
Basics of genome editing technology and its application in livestock species.
Recent progress in dissecting molecular recognition by DNA polymerases with non-native substrates.
Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice.
The polymerase chain reaction (PCR): a valuable method for retroviral detection.
Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase.
[DNA polymerase eta: from a DNA repair-deficient genetic disease to the discovery of a novel DNA polymerase]
Giant Cell Tumors
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Giardiasis
AGA Technical Review on the Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D).
Drug resistance in Giardia: Mechanisms and alternative treatments for Giardiasis.
Gingivitis
Bovine lactoferrin and piroxicam as an adjunct treatment for lymphocytic-plasmacytic gingivitis stomatitis in cats.
Clinical, Immune, and Microbiome Traits of Gingivitis and Peri-implant Mucositis.
Concentrations of thiocyanate, hypothiocyanite, 'free' and 'total' lysozyme, lactoferrin and secretory IgA in resting and stimulated whole saliva of children aged 12-14 years and the relationship with plaque accumulation and gingivitis.
Correlation of lactoferrin with neutrophilic inflammation in body fluids.
Decrease in salivary lactoferrin output in chronically intoxicated alcohol-dependent patients.
Elastase and lactoferrin in gingival crevicular fluid: possible indicators of a granulocyte-associated specific host response.
Lactoferrin in Gingival Crevicular Fluid and Peripheral Blood during Experimental Gingivitis.
Lysozyme and lactoferrin quantitation in the crevicular fluid.
The relationship between elastase and lactoferrin in healthy, gingivitis and periodontitis sites.
Glioblastoma
Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility.
Attenuated diphtheria toxin mediates siRNA delivery.
Aurora kinase B siRNA-loaded lactoferrin nanoparticles potentiate the efficacy of temozolomide in treating glioblastoma.
Brain targeted delivery of carmustine using solid lipid nanoparticles modified with tamoxifen and lactoferrin for antitumor proliferation.
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins.
Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells.
Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma.
Immunohistochemical detection of lactoferrin in human astrocytomas and multiforme glioblastomas.
Immunotoxin pharmacokinetics: a comparison of the anti-glioblastoma bi-specific fusion protein (DTAT13) to DTAT and DTIL13.
In vitro and in vivo effect of human lactoferrin on glioblastoma growth.
Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery.
Intracranial therapy of glioblastoma with the fusion protein DTIL13 in immunodeficient mice.
Native and iron-saturated bovine lactoferrin differently hinder migration in a model of human glioblastoma by reverting epithelial-to-mesenchymal transition-like process and inhibiting interleukin-6/STAT3 axis.
Natural substances to potentiate canonical glioblastoma chemotherapy.
Reoxygenation of hypoxic glioblastoma multiforme cells potentiates the killing effect of an interleukin-13-based cytotoxin.
Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma.
Targeting delivery of etoposide to inhibit the growth of human glioblastoma multiforme using lactoferrin- and folic acid-grafted poly(lactide-co-glycolide) nanoparticles.
Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT.
Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.
Transferrin receptor-mediated endocytosis: a useful target for cancer therapy.
Glioma
A comparison of the effect of hyperthermia on DNA polymerase in hamster and human glioma cells.
A comparison of the enhancement of radiation sensitivity and DNA polymerase inactivation by hyperthermia in human glioma cells.
A pH-sensitive hyaluronic acid prodrug modified with lactoferrin for glioma dual-targeted treatment.
Adenovirus-Mediated CRM197 Sensitizes Human Glioma Cells to Gemcitabine by the Mitochondrial Pathway.
Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide.
Apoptotic DNA endonuclease (DNase-gamma) gene transfer induces cell death accompanying DNA fragmentation in human glioma cells.
Cell-type specific factors bind to regulatory elements located downstream of the TATA-box element in the mouse myelin basic protein (MBP) gene promoter.
Characterization of estrogen-responsive mouse lactoferrin promoter.
Citric acid coated ultrasmall superparamagnetic iron oxide nanoparticles conjugated with lactoferrin for targeted negative MR imaging of glioma.
Co-administration of dual-targeting nanoparticles with penetration enhancement peptide for antiglioblastoma therapy.
Conjugation Magnetic PAEEP-PLLA Nanoparticles with Lactoferrin as a Specific Targeting MRI Contrast Agent for Detection of Brain Glioma in Rats.
Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene.
Hyperthermia radiosensitization in human glioma cells comparison of recovery of polymerase activity, survival, and potentially lethal damage repair.
Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.
Knockdown of DNA polymerase ? relieved the chemoresistance of glioma via inhibiting the PI3K/AKT signaling pathway.
Lactoferrin conjugated iron oxide nanoparticles for targeting brain glioma cells in magnetic particle imaging.
Lactoferrin for Mental Health: Neuro-Redox Regulation and Neuroprotective Effects across the Blood-Brain Barrier with Special Reference to Neuro-COVID-19.
Lactoferrin functionalized PEG-PLGA nanoparticles of shikonin for brain targeting therapy of glioma.
Lactoferrin modified doxorubicin-loaded procationic liposomes for the treatment of gliomas.
Lactoferrin modified graphene oxide iron oxide nanocomposite for glioma-targeted drug delivery.
Lactoferrin-modified poly(ethylene glycol)-grafted BSA nanoparticles as a dual-targeting carrier for treating brain gliomas.
Lactoferrin/phenylboronic acid-functionalized hyaluronic acid nanogels loading doxorubicin hydrochloride for targeting glioma.
Mechanisms and therapeutic implications of hypermutation in gliomas.
N-methylpurine DNA glycosylase and DNA polymerase {beta} modulate BER inhibitor potentiation of glioma cells to temozolomide.
Nuclear and cytoplasmic delivery of lactoferrin in glioma using chitosan nanoparticles: Cellular location dependent-action of lactoferrin.
OmpA is the critical component for Escherichia coli invasion-induced astrocyte activation.
Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433).
pH/temperature sensitive magnetic nanogels conjugated with Cy5.5-labled lactoferrin for MR and fluorescence imaging of glioma in rats.
Promising Fusion Protein Design to Target the U87 MG Glioma Cell Line.
Recombinant baculovirus containing the diphtheria toxin A gene for malignant glioma therapy.
Regulated expression of the diphtheria toxin A gene in human glioma cells using prokaryotic transcriptional control elements.
Regulation of cellular growth, apoptosis, and Akt activity in human U251 glioma cells by a combination of cisplatin with CRM197.
Reverse transformation and genome exposure in the C6 glial tumor cell line.
SRL-Coated PAMAM Dendrimer Nano-Carrier for Targeted Gene Delivery to the Glioma Cells and Competitive Inhibition by Lactoferrin.
Technology evaluation: TransMID, KS Biomedix/Nycomed/Sosei/PharmaEngine.
The effect of immunotoxin against human glioma cells.
The major promoter of the rat insulin-like growth factor-I gene binds a protein complex that is required for basal expression.
The place of hydroxyurea in the treatment of primary brain tumors.
[Construction and expression of the fusion protein DT389-hIL-13 and its cytotoxicity to glioma cell lines]
Glomerulonephritis
Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis.
Clinical significance of antineutrophil cytoplasmic autoantibodies with specificity for lactoferrin in renal diseases.
Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis.
Monogenic lupus due to DNASE1L3 deficiency in a pediatric patient with urticarial rash, hypocomplementemia, pulmonary hemorrhage, and immune-complex glomerulonephritis.
Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.
STUDIES IN GLOMERULONEPHRITIS : I. A QUANTITATIVE STUDY OF THE REACTION OF THE KIDNEY TO DIPHTHERIA TOXIN.
STUDIES IN GLOMERULONEPHRITIS : II. A FORM OF ACUTE GLOMERULONEPHRITIS PRODUCED WITH DIPHTHERIA TOXIN AND BACILLUS COLI.
THE PRODUCTION OF ARTERIOSCLEROSIS AND GLOMERULONEPHRITIS IN THE RABBIT BY INTRAVENOUS INJECTIONS OF DIPHTHERIA TOXIN.
Glomerulonephritis, IGA
[Anti-myeloperoxidase and anti-lactoferrin antibodies in patients with IgA nephropathy and Henoch-Schönlein purpura]
Goiter
Lactoferrin in thyroid lesions: immunoreactivity in fine needle aspiration biopsy samples.
Gonorrhea
[Characteristic of biological properties of Neisseria gonorrhoeae and parameters of local immunity during urogenital gonococcal infection]
[Risk factors for violations of the fertility in men living in urban areas].
[The comparative characteristic of immune status of males with bacterial inflammatory urogenital pathology of different etiology in the city of Orenburg].
Gout
Effect of intravenous administration of crystalline pancreatic desoxyribonuclease in patients with gout.
Lactoferrin and lysozyme levels in synovial fluid: differential indices of articular inflammation and degradation.
Graft vs Host Disease
Corynebacterium diphtheriae: Diphtheria Toxin, the tox Operon, and Its Regulation by Fe2+ Activation of apo-DtxR.
Immunotoxins in cancer therapy: Review and update.
Gram-Negative Bacterial Infections
Deciphering the roles of outer membrane protein A extracellular loops in the pathogenesis of Escherichia coli K1 meningitis.
Outer membrane protein A and OprF: versatile roles in Gram-negative bacterial infections.
Granuloma
Formation and Disordered Degradation of Neutrophil Extracellular Traps in Necrotizing Lesions of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.
Immunohistochemical distribution of ferritin, lactoferrin, and transferrin in granulomas of bovine paratuberculosis.
Lactoferrin modulation of mycobacterial cord factor trehalose 6-6'-dimycolate induced granulomatous response.
Lactoferrin reduces mycobacterial M1-type inflammation induced with trehalose 6,6'-dimycolate and facilitates the entry of fluoroquinolone into granulomas.
Lactoferrin, lysozyme, and beta 2-microglobulin levels in cerebrospinal fluid: differential indices of CNS inflammation.
Lactoferrin: A Modulator for Immunity against Tuberculosis Related Granulomatous Pathology.
The distribution of ferritin, lactoferrin and transferrin in granulomatous lymphadenitis of bovine paratuberculosis.
Granulomatous Disease, Chronic
Correlation of human neutrophil secretion, chemoattractant receptor mobilization, and enhanced functional capacity.
Graves Disease
A nonsense mutation in exon 2 of the DNase I gene is not present in UK subjects with systemic lupus erythematosus and Graves' disease: Comment on the article by Rood et al.
High levels of DNA polymerase ? mRNA corresponding with the high activity in Graves' thyroid tissue.
Human leucocyte antigen DNA typing in Singaporean Chinese patients with Graves' disease.
Pyoderma gangrenosum with secondary pyarthrosis following propylthiouracil.
Graves Ophthalmopathy
[Expressions of lysozyme C and lactoferrin in tears of thyroid-associated ophthalmopathy patients].
Haemophilus Infections
Iron-binding proteins in sputum of chronic bronchitis patients with Haemophilus influenzae infections.
Protection of infant rats from Haemophilus influenzae type b infection by antiserum to purified outer membrane protein a.
Head and Neck Neoplasms
Evaluation of serum alkaline DNase activity in treatment monitoring of head and neck cancer patients.
Lactoferrin down-regulates G1 cyclin-dependent kinases during growth arrest of head and neck cancer cells.
Predictive value of serum alkaline DNase activity variations in treatment of head and neck cancer.
Healthcare-Associated Pneumonia
Overproduction of Outer Membrane Protein A by Acinetobacter baumannii as a Risk Factor for Nosocomial Pneumonia, Bacteremia, and Mortality Rate Increase.
Hearing Loss
The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma.
Heart Diseases
Circulating cell-free DNA fragment analysis by microchip electrophoresis and its relationship with DNase I in cardiac diseases.
Recombinant human deoxyribonuclease improves atelectasis in mechanically ventilated children with cardiac disease.
Heart Failure
Diagnostic value of lactoferrin analysis in pleural effusions.
Diphtheria toxin-induced autophagic cardiomyocyte death plays a pathogenic role in mouse model of heart failure.
Elevated DNase I levels in human idiopathic dilated cardiomyopathy: an indicator of apoptosis?
Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis.
[Iron and iron-binding proteins in the differential diagnosis of pleural effusion]
Heart Septal Defects, Ventricular
The Effect of Methylprednisolone on Plasma Concentrations of Neutrophil Gelatinase-Associated Lipocalin in Pediatric Heart Surgery.
Helicobacter Infections
Effect of lactoferrin on Helicobacter felis induced gastritis.
Recombinant human lactoferrin is effective in the treatment of Helicobacter felis-infected mice.
Helminthiasis
Observations on the impact of breast-feeding and of intestinal helminthiasis on a rapid agglutination assay for fecal lactoferrin in Nicaraguan children with diarrhea.
Hemangiosarcoma
[Breast hemangiosarcoma. Contribution of a case and review of the literature. Study of viral particles and RNA dependent DNA polymerase (inverse transcriptase) activity]
Hematologic Neoplasms
Clinical Activity and Tolerability of SL-401 (Tagraxofusp): Recombinant Diphtheria Toxin and Interleukin-3 in Hematologic Malignancies.
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies.
Hematuria
In Vivo Imaging of Inflamed Glomeruli Reveals Dynamics of Neutrophil Extracellular Trap Formation in Glomerular Capillaries.
Hemochromatosis
Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages.
Lactoferrin uptake and iron processing into macrophages: a study in familial haemochromatosis.
Hemolytic-Uremic Syndrome
Colicinogeny of O157:H7 enterohemorrhagic Escherichia coli and the shielding of colicin and phage receptors by their O-antigenic side chains.
Hemoperitoneum
[Effects of streptokinase, streptodornase and fibrinolytic enzymes of pancreatic extraction on experimental hemoperitoneum.]
Hemopneumothorax
Spontaneous hemopneumothorax, with reference to the use of streptokinase and streptodornase.
Hemoptysis
Monogenic lupus due to DNASE1L3 deficiency in a pediatric patient with urticarial rash, hypocomplementemia, pulmonary hemorrhage, and immune-complex glomerulonephritis.
Pulmonary complications of cystic fibrosis.
[Respiratory evolution of patient with mucoviscidosis treated with mucolytic agents plus dornase alfa]
Hemothorax
The treatment of hemothorax; with particular reference to the use of streptokinase and streptodornase.
Tissue plasminogen activator and pulmozyme for postoperative-retained hemothorax: A safe alternative to postoperative re-exploration.
[3 Cases of hemothorax after extrapleural pneumothorax, treated by injections of streptokinase and streptodornase.]
[Decortication of the lung and resection of the cavity in the treatment of chronic empyema; review of cases treated by other methods and use of streptodornase and streptokinase in coagulated hemothorax.]
[First results of the use of streptodornase and streptokinase in hemothorax secondary to creation of extra-pleural pneumothorax.]
[Streptokinase and streptodornase therapy of empyema and postoperative hemothorax.]
[Streptokinase and streptodornase: its use in hemothorax following extrapleural pneumothorax.]
Hepatitis
A newly identified hepatitis B type virus in tree squirrels.
Activities of arabinosyladenine monophosphate and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against ground squirrel hepatitis virus in vivo as determined by reduction in serum virion-associated DNA polymerase.
Acute flares in chronic hepatitis B: the natural and unnatural history of an immunologically mediated liver disease.
Acute type A hepatitis in three patients with chronic HBV infection.
Acutely exaggerated hepatitis B induced by the withdrawal of immunosuppressants in a seroconverted renal transplant recipient: report of a case.
Anti-LSP antibodies in acute liver disease.
Antiviral activity and intracellular metabolism of bis(tButylSATE) phosphotriester of beta-L-2',3'dideoxyadenosine, a potent inhibitor of HIV and HBV replication.
Bioinformatic Identification of Rare Codon Clusters (RCCs) in HBV Genome and Evaluation of RCCs in Proteins Structure of Hepatitis B Virus.
Bovine lactoferrin induces interleukin-11 production in a hepatitis mouse model and human intestinal myofibroblasts.
Bovine lactoferrin ingestion protects against inflammation via IL-11 induction in the small intestine of mice with hepatitis.
Bovine lactoferrin potently inhibits liver mitochondrial 8-OHdG levels and retrieves hepatic OGG1 activities in Long-Evans Cinnamon rats.
Changes in hepatitis B virus DNA polymerase in relation to the outcome of acute hepatitis type B.
Chronic evolution of acute hepatitis type B: prevalence and predictive markers.
Chronic hepatitis. Aetiology and current management.
Clinicopathological response of HBsAg-positive chronic active hepatitis to adenine arabinoside: lack of correlation with DNA polymerase response.
Comparison of DNA polymerase and radioimmune assays for the detection of hepatitis B antigens and antibodies.
Comparison of properties of woodchuck hepatitis virus and human hepatitis B virus endogenous DNA polymerases.
Correlation of e antigen, DNA polymerase activity, and Dane particles in chronic benign and chronic active type B hepatitis infections.
Dane particle DNA polymerase and HBeAg: impact on clinical, laboratory, and histologic findings in hepatitis B-associated chronic liver disease.
Deoxyribonuclease I and II activities in liver and spleen of mice experimentally infected by mouse hepatitis virus.
Diagnosis of hepatitis B by Dane particle associated DNA polymerase assay.
Differential effects of fibroblast and leucocyte interferon in HBsAg positive chronic active hepatitis.
e antigen and antibody, DNA polymerase, and inhibitors of DNA polymerase in acute and chronic hepatitis.
Early lesions and development of primary hepatocellular carcinoma in man--association with hepatitis B viral infection.
Effects of an extract from Phyllanthus niruri on hepatitis B and woodchuck hepatitis viruses: in vitro and in vivo studies.
Effects of human recombinant interleukin 2 in patients with chronic hepatitis B: a preliminary report.
Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B.
Effects of suramin on in vitro HBsAg production by PLC/PRF/5 cells and hepatitis B virus DNA polymerase activity.
Failure of immune serum globulin to prevent hepatitis B virus infection in infants born to HBsAg-positive mothers.
Failure to detect naturally occurring serum inhibitors of hepatitis B virus deoxyribonucleic acid polymerase.
Fibroblast interferon treatment of a patient with chronic active hepatitis. Increased number of circulating T lymphocytes and elimination of rosette-inhibitory factor.
Genetic variation among hepatitis B and related viruses.
Hepatitis B virus and primary hepatocellular carcinoma: treatment of HBV carriers with Phyllanthus amarus.
Hepatitis B virus variants in an HIV-HBV co-infected patient at different periods of antiretroviral treatment with and without lamivudine.
Hepatitis B-specific DNA polymerase activity during post-transfusion hepatitis.
Histopathologic resolution of adult liver transplantation adenovirus hepatitis with cidofovir and intravenous immunoglobulin: a case report.
Inhibition of human and woodchuck hepatitis virus DNA polymerase by the triphosphates of acyclovir, 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and E-5-(2-bromovinyl)-2'-deoxyuridine.
Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks.
Lactoferrin protects against development of hepatitis caused by sensitization of Kupffer cells by lipopolysaccharide.
Long-term follow-up of chronic hepatitis patients with HBsAg, HBeAg and Dane particles associated DNA polymerase in serum.
Lymphocyte transformation and hepatitis. I. Impairment of thymidine incorporation and DNA polymerase activity.
Main properties of duck hepatitis B virus DNA polymerase: comparison with the human and woodchuck hepatitis B virus DNA polymerases.
Mutations in the hepatitis B virus preS2 region and abrogated receptor activity for polymerized human albumin.
Natural history of hepatitis B virus infection in renal transplant recipients--a fifteen-year follow-up.
Naturally occurring infection of Pekin duck embryos by duck hepatitis B virus.
New targets and inhibitors of HBV replication to combat drug resistance.
No in vivo effect of trisodium phosphonoformate on woodchuck hepatitis virus production.
Non-a, non-b hepatitis: identification of hepatitis-B-like virus particles in serum and liver.
Peroxidase-anti-peroxidase detection of hepatitis B surface and core antigen in liver biopsy specimens from patients with chronic type B hepatitis.
Pharmacology of beta-L-thymidine and beta-L-2'-deoxycytidine in HepG2 cells and primary human hepatocytes: relevance to chemotherapeutic efficacy against hepatitis B virus.
Prednisone withdrawal followed by recombinant alpha interferon in the treatment of chronic type B hepatitis. A randomized, controlled trial.
Presence of HBeAg, DNA polymerase activity, Dane particle in different categories of HBsAg carriers and evidence of hepatitis type B infection in their family contacts.
Prevalence and heterogeneity of serum DNA polymerase activity in patients with non-A, non-B hepatitis and HBsAg-negative blood donors with elevated SGPT.
Prolonged (6 months) treatment of chronic hepatitis B virus infection with recombinant leukocyte A interferon.
Prospective trial of recombinant leucocyte interferon in chronic hepatitis B: a 10-month follow-up study.
Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro.
Quantitative relationship between HBeAg and DNA polymerase activity in sera from patients with chronic active hepatitis during a three-month period.
Reactivation of chronic hepatitis B virus infection by cancer chemotherapy.
Reactivation of chronic type B hepatitis presenting as acute viral hepatitis.
Recent advances in the identification of hepatitis viruses.
Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis.
Suramin treatment for chronic active hepatitis B--toxic and ineffective.
Trans-complementation of the C gene of human and the P gene of woodchuck hepadnaviruses.
Transient antibodies to DNA polymerase in acute hepatitis B and related diseases.
Trisodium phosphonoformate inhibits woodchuck hepatitis virus associated DNA polymerase.
Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure.
Viral Hepatitis and Iron Dysregulation: Molecular Pathways and the Role of Lactoferrin.
Viral hepatitis, type B, DNA polymerase activity and antibody to hepatitis B core antigen.
Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations.
[Change of hepatitis B surface antigen in serum from patients with chronic hepatitis B]
[Delta infection in HBsAg carriers]
[Desoxyribonuclease I and II activity of the liver and spleen during experimental mouse hepatitis caused by MHV-3 virus]
[Hepatitis B virus DNA polymerase activity in various clinical forms of HBV infection]
[Identification of a virus similar to hepatitis B virus in non-A non-B hepatitis]
[Serum lactoferrin levels in children with viral hepatitis A].
[Significance of the expression of pre-S proteins in mononuclear blood cells in chronic hepatitis caused by the hepatitis B virus]
[Study of salivary lactoferrin in prophylactic examinations]
[The activity of DNA polymerase in the blood of non-A, non-B hepatitis patients, and discussion on retrovirus as the causative agent]
Hepatitis A
Immunogenicity and safety of concomitant administration of a combined hepatitis a/b vaccine and a quadrivalent meningococcal conjugate vaccine in healthy adults.
[Development of a two-site immunoassay using polyclonal antibodies for determination of lactoferrin in human blood]
[Serum lactoferrin levels in children with viral hepatitis A].
[Urine deoxyribonuclease activity in children with infectious hepatitis]
Hepatitis B
A modified technique for the detection of hepatitis B virus-specific DNA polymerase.
A pilot study of 2',3'-dideoxyinosine for the treatment of chronic hepatitis B.
Acute hepatitis A infection in hepatitis B chimpanzee carriers.
Adefovir dipivoxil: focus on its use in the treatment of chronic hepatitis B.
Adenine arabinoside 5'-monophosphate treatment of chronic type B hepatitis.
Adenine arabinoside monophosphate (vidarabine phosphate) in combination with human leukocyte interferon in the treatment of chronic hepatitis B. A randomized, double-blinded, placebo-controlled trial.
Adenine arabinoside therapy in HBsAg-positive chronic liver disease: a controlled study.
Analysis of DNA polymerase reaction products for detecting hepatitis B virus in serum--comparison with spot hybridization technique.
Anti-hepatitis B virus activity of wogonin in vitro and in vivo.
Anti-LSP antibodies in acute liver disease.
Antibody responses elicited by a polyvalent vaccine containing synthetic diphtheric, streptococcal and hepatitis peptides coupled to the same carrier.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Antilactoferrin antibodies in autoimmune liver diseases.
Antiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infection.
Antiviral activities of whey proteins.
Antiviral drugs for viruses other than human immunodeficiency virus.
Binding sensitivity of adefovir to the polymerase from different genotypes of HBV: molecular modeling, docking and dynamics simulation studies.
Broad specificity of the hepatitis B enhancer function.
Carbonyl J Acid Derivatives Block Protein Priming of Hepadnaviral P Protein and DNA-Dependent DNA Synthesis Activity of Hepadnaviral Nucleocapsids.
CDC42-Interacting Protein 4 Gene Is Down Trans-Regulated by HBV DNA polymerase Trans Activated Protein 1.
Cell type-dependent regulation of the activity of the negative regulatory element of the hepatitis B virus core promoter.
Changes in hepatitis B virus DNA polymerase in relation to the outcome of acute hepatitis type B.
Characterization of hepatitis B virus DNA polymerase.
Characterization of novel hepadnaviral RNA species accumulated in hepatoma cells treated with viral DNA polymerase inhibitors.
Characterization of the hepatitis B virus large surface antigen promoter Sp1 binding site.
Chemical inactivation of hepatitis B virus: the effect of disinfectants on virus-associated DNA polymerase activity, morphology and infectivity.
Chronic hepatitis B: correlation between viral replication and clinical course.
Chronic hepatitis B: What should be the goal for new therapies?
Chronic hepatitis. Aetiology and current management.
Clinical evaluation of intramuscular administration of natural interferon-gamma in the treatment of chronic hepatitis B.
Cloning a defined region of DNA using a limited action of DNA polymerase: application to dissection of hepatitis B virus surface antigen gene.
Coinfection of hepatitis C virus in patients with chronic hepatitis B infection.
Combination therapy of glycyrrhizin withdrawal and human fibroblast interferon for chronic hepatitis B.
Combined hepatitis B immune globulin and vaccine for postexposure prophylaxis of accidental hepatitis B virus infection in hemodialysis staff members: comparison with immune globulin without vaccine in historical controls.
Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells.
Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5-methyldeoxycytidines and of other nucleoside analogs.
Comparison of DNA polymerase and radioimmune assays for the detection of hepatitis B antigens and antibodies.
Comparison of mass spectrometric analysis and TRUGENE HBV genotyping for monitoring lamivudine resistance in chronic hepatitis B patients.
Comparison of properties of woodchuck hepatitis virus and human hepatitis B virus endogenous DNA polymerases.
Comparison of serum hepatitis B virus replication markers in patients with chronic hepatitis B: studies on HBeAg/anti-HBe system, viral DNA polymerase and HBV-DNA.
Computational model of hepatitis B virus DNA polymerase: molecular dynamics and docking to understand resistant mutations.
Correlation of HBV DNA PCR and HBeAg in hepatitis B carriers.
Correlation of improved hepatitis?B surface antigen detection limits with hepatitis?B virus DNA nucleic acid test yield in blood donations.
Dane particle-associated DNA polymerase and e antigen: relation to chronic hepatitis among carriers of hepatitis B surface antigen.
Dane particles, DNA polymerase, and e-antigen in two different categories of hepatitis B antigen carriers.
Decrease in serum levels of markers of hepatic connective tissue turnover during and after treatment of chronic hepatitis B with interferon-alpha.
Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.
Detection of antibodies against DNA polymerase of hepatitis B virus in HBsAg-positive sera using ELISA.
Detection of antibodies against the polymerase gene product in hepatitis B virus infection.
Detection of DNA polymerase activities associated with purified duck hepatitis B virus core particles by using an activity gel assay.
Detection of HBs antigen, DNA polymerase activity, and hepatitis B virus DNA in tears: relevance to hepatitis B transmission by tears.
Detection of hepatitis B virus DNA in HBsAg chronic carriers using a liquid phase molecular hybridization (Abbott HBV DNA) and the DNA polymerase assay: comparison of results.
Detection of hepatitis B virus genotypic resistance mutations by coamplification at lower denaturation temperature-PCR coupled with sanger sequencing.
Detection of hepatitis B virus YMDD variants using mass spectrometric analysis of oligonucleotide fragments.
Detection of YMDD mutant using a novel sensitive method in chronic liver disease type B patients before and during lamivudine treatment.
Determination of serum DNA polymerase activities in hepatitis B carriers.
Diagnosis of hepatitis B by Dane particle associated DNA polymerase assay.
Diagnostic Value of Serum DNASE1L3 in Hepatitis B Virus-Related Hepatocellular Carcinoma.
Different fates of hepatitis B virus markers during plasma fractionation: a clue to the infectivity of blood derivatives.
Different levels of hepatitis B virus replication among hepatitis Be antigen-positive chronic carriers.
Differential activation of hepatitis B DNA polymerase by detergent and salt.
Differential distribution of hepatitis B core and E antigens in hepatocytes: analysis by monoclonal antibodies.
Differential effects of fibroblast and leucocyte interferon in HBsAg positive chronic active hepatitis.
Diminished responsiveness of homosexual men to antiviral therapy for HBsAg-positive chronic liver disease.
Discordant e antigen, DNA polymerase activity, and Dane particle responses in two patients representing an index case-contact case pair with hepatitis B virus infection.
Discovery of novel hepatitis B virus nucleocapsid assembly inhibitors.
DNA and DNA polymerase in the core of the Dane particle of hepatitis B.
DNA and DNA polymerase of a virus-like particle in hepatitis B.
DNA Polymerase ? Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus.
DNA polymerase activity of hepatitis B virus particles: differential inhibition by L-enantiomers of nucleotide analogs.
DNA polymerase associated with human hepatitis B antigen.
DNA polymerase in the core of the human hepatitis B virus candidate.
DNA Polymerase in the Core of the Human Hepatitis B Virus.
DNA polymerase inhibitors for treating hepatitis B: a safety evaluation.
DNA synthesized in the hepatitis B Dane particle DNA polymerase reaction.
Downregulation of SWI5 and CTC1 genes: hepatitis B virus DNA polymerase transactivated protein 1-mediated inhibition of DNA repair.
Duck hepatitis B virus model for screening of antiviral agents from medicinal herbs.
Duck hepatitis B virus polymerase produced by in vitro transcription and translation possesses DNA polymerase and reverse transcriptase activities.
Duck hepatitis B virus: DNA polymerase and reverse transcriptase activities of replicative complexes isolated from liver and their inhibition in vitro.
e antigen and antibody, DNA polymerase, and inhibitors of DNA polymerase in acute and chronic hepatitis.
e-Antigen: a link between immune response and infectivity in hepatitis B?
Early diagnosis of Hepatitis B by Dane particle associated DNA polymerase assay.
Early lesions and development of primary hepatocellular carcinoma in man--association with hepatitis B viral infection.
Editorial: DNA polymerase and hepatitis B antigen.
Effect of corticosteroid therapy on levels of antibody to hepatitis B core antigen in patients with chronic type B hepatitis.
Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis.
Effects of an extract from Phyllanthus niruri on hepatitis B and woodchuck hepatitis viruses: in vitro and in vivo studies.
Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B.
Effects of Phyllanthus plant extracts on duck hepatitis B virus in vitro and in vivo.
Effects of suramin on in vitro HBsAg production by PLC/PRF/5 cells and hepatitis B virus DNA polymerase activity.
Enhanced oral absorption and antiviral activity of 1-O-octadecyl-sn-glycero-3-phospho-acyclovir and related compounds in hepatitis B virus infection, in vitro.
Evidence against the postulated identity of e-antigen with DNA polymerase associated with the hepatitis B candidate virus.
Expression of cloned hepatitis B virus DNA in human cell cultures.
Expression of the active human and duck hepatitis B virus polymerases in heterologous system of Pichia methanolica.
Failure of antibody to e antigen to precipitate Dane particles containing DNA polymerase activity and hepatitis B core antigen.
Failure to detect naturally occurring serum inhibitors of hepatitis B virus deoxyribonucleic acid polymerase.
Fibroblast interferon treatment of a patient with chronic active hepatitis. Increased number of circulating T lymphocytes and elimination of rosette-inhibitory factor.
Filtration and immunoprecipitation in the elimination of DNA polymerase activity associated with bacterial contamination of sera positive for hepatitis B e antigen and its corresponding antibody.
Frangulosid as a novel hepatitis B virus DNA polymerase inhibitor: a virtual screening study.
Free and integrated forms of hepatitis B virus DNA in human hepatocellular carcinoma cells (PLC/342) propagated in nude mice.
Fulminant hepatitis B in successive female sexual partners of two anti-HBe-positive males.
Gateways to clinical trials.
Genetically engineered diphtheria toxin fusion proteins carrying the hepatitis B surface antigen.
Genotyping the hepatitis B virus with a fragment of the HBV DNA polymerase gene in Shenyang, China.
Glycoconjugate vaccines and immune interference: A review.
Glycyrrhizin withdrawal followed by human lymphoblastoid interferon in the treatment of chronic hepatitis B.
Hbc ag, anti-HBC, and DNA polymerase activity in transfused recipients followed prospectively.
HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine.
HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways.
HBV genotypic resistance to lamivudine in kidney recipients and hemodialyzed patients.
Hemagglutination and immunofluorescence studies on polymerized human serum albumin binding activity in chronic hepatitis B virus infection.
Hepatitis B and serum DNA polymerase activities in chimpanzees.
Hepatitis B core particles with endogenous DNA polymerase activity from chimpanzee liver.
Hepatitis B e antigen, DNA polymerase activity, and infection of household contacts with hepatitis B virus.
Hepatitis B surface antigen/IgM complexes: relation to receptors for polymerized human serum albumin, hepatitis B virus (HBV) DNA polymerase activity and HBV markers.
Hepatitis B today: clinical and diagnostic overview.
Hepatitis B viral DNA-RNA hybrid molecules in particles from infected liver are converted to viral DNA molecules during an endogenous DNA polymerase reaction.
Hepatitis B virus (HBV) reactivation after cytotoxic or immunosuppressive therapy--pathogenesis and management.
Hepatitis B virus associated DNA polymerase inactivation in factor IX concentrates.
Hepatitis B virus carrier with low titer of antibody to hepatitis B core antigen.
Hepatitis B virus DNA polymerase activity and hepatitis B e antigen (HBeAg)/anti-HBe status among type B chronic liver diseases.
Hepatitis B Virus DNA Polymerase Displays an Anti-Apoptotic Effect by Interacting with Elongation Factor-1 Alpha-2 in Hepatoma Cells.
Hepatitis B virus DNA polymerase gene polymorphism based prediction of genotypes in chronic HBV patients from Western India.
Hepatitis B virus genetic diversity.
Hepatitis B virus genotyping among chronic hepatitis B patients with resistance to treatment with lamivudine in the City of Ribeirão Preto, State of São Paulo.
Hepatitis B virus morphogenesis.
Hepatitis B virus particles of plasma and liver contain viral DNA-RNA hybrid molecules.
Hepatitis B virus replication and mutation are autoregulated by interactions between surface antigen and HBeAg and the HBV DNA polymerase: a functional model with therapeutic implications.
Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the 'a' epitope of the surface antigen are sensitive to ganciclovir.
Hepatitis B virus: DNA polymerase activity of deletion mutants.
Hepatitis virus infection in an isolated Canadian Inuit (Eskimo) population.
Hepatitis viruses: characterization and diagnostic techniques.
High frequency of functional anti-YMDD and -mutant cytotoxic T lymphocytes after in vitro expansion correlates with successful response to lamivudine therapy for chronic hepatitis B.
Human lymphoblastoid and fibroblast interferon in the treatment of chronic hepatitis B.
Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus.
Identification of factor-binding sites in the duck hepatitis B virus enhancer and in vivo effects of enhancer mutations.
Identification of paired immunoglobulin-like type 2 receptor ? as hepatitis B virus DNA polymerase transactivated protein 1 interacting proteins.
Immunoelectron microscopic observation of hepatitis B surface antigen on the surface of liver cells from patients with hepatitis B virus infection.
In vitro replication and expression of hepatitis B virus from chronically infected primary chimpanzee hepatocytes.
Inactivation of DNA-polymerase associated with hepatitis B virus.
Inactivation of hepatitis B virus: evaluation of the efficacy of the disinfectant 'Solprogel' using a DNA-polymerase activity assay.
Inactivation of human hepatitis B virus DNA polymerase by pyridoxal 5'-phosphate.
Incomplete inactivation of hepatitis B virus after heat treatment at 60 C for 10 hours.
Incorporation of deoxyribonucleotides and ribonucleotides by a dNTP-binding cleft mutated reverse transcriptase in hepatitis B virus core particles.
Increased DNA polymerase fidelity of the Lamivudine resistant variants of human hepatitis B virus DNA polymerase.
Inhibition of HBV infection by bovine lactoferrin and iron-, zinc-saturated lactoferrin.
Inhibition of hepatitis B Dane particle DNA polymerase activity by pyrophosphate analogs.
Inhibition of hepatitis B DNA polymerase by intercalating agents.
Inhibition of hepatitis B virus DNA polymerase by 3'-azido-3'-deoxythymidine triphosphate but not by its threo analog.
Inhibition of hepatitis B virus DNA polymerase by 3'-fluorothymidine triphosphate and other modified nucleoside triphosphate analogs.
Inhibition of hepatitis B virus DNA polymerase by enantiomers of penciclovir triphosphate and metabolic basis for selective inhibition of HBV replication by penciclovir.
Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.
Inhibition of hepatitis B virus specific DNA polymerase by intercalating agents.
Inhibition of human and woodchuck hepatitis virus DNA polymerase by the triphosphates of acyclovir, 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and E-5-(2-bromovinyl)-2'-deoxyuridine.
Inhibition of human hepatitis B virus DNA polymerase and duck hepatitis B virus DNA polymerase by triphosphates of thymidine analogs and pharmacokinetic properties of the corresponding nucleosides.
Inhibition of RNA- and DNA-dependent duck hepatitis B virus DNA polymerase activity by nucleoside and pyrophosphate analogs.
Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir.
Ionic requirements of the DNA polymerase associated with serum hepatitis B antigen.
Isolation, characterization, and hepatoprotective properties of betulinic acid and ricinine from Tetracarpidium conophorum seeds (Euphorbiaceae).
Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity.
Kinetics of heat inactivation of hepatitis B virus-associated DNA polymerase.
Lactoferrin inhibits hepatitis B virus infection in cultured human hepatocytes.
Lamivudine: in children and adolescents with chronic hepatitis B virus infection.
Long-term outcomes and dynamics of mutants associated with Lamivudine-adefovir rescue therapy in patients with lamivudine-resistant chronic hepatitis B.
Main properties of duck hepatitis B virus DNA polymerase: comparison with the human and woodchuck hepatitis B virus DNA polymerases.
Masking oligonucleotides improve sensitivity of mutation detection based on guanine quenching.
Maternal transmission of duck hepatitis B virus in pedigree Pekin ducks.
Micromethod for phosphonoformate inhibition assay of hepatitis B viral DNA polymerase.
Mimicry between the hepatitis B virus DNA polymerase and the antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis B virus infection.
Molecular basis for the antiviral and anticancer activities of unnatural L-beta-nucleosides.
Molecular docking studies of phytochemicals from Phyllanthus niruri against Hepatitis B DNA Polymerase.
Molecular mimicry between a uveitopathogenic site of S-antigen and viral peptides. Induction of experimental autoimmune uveitis in Lewis rats.
Multiplexed measurement of serum antibodies using an array biosensor.
Mutation of the core region of HBV-DNA and submassive hepatic necrosis in patients with anti-HBe-positive chronic hepatitis B.
Mutations in HBV DNA Polymerase Associated With Nucleos(t)ide Resistance Are Rare in Treatment-naive Patients.
Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro.
Mutations in hepatitis B virus polymerase are associated with the postoperative survival of hepatocellular carcinoma patients.
No effect of zidovudine on hepatitis B virus replication in homosexual men with symptomatic HIV-1 infection.
No in vivo effect of trisodium phosphonoformate on woodchuck hepatitis virus production.
Non-A, non-B hepatitis in persistent carriers of hepatitis B virus.
Non-A, Non-B hepatitis virus: identification of a core antigen-antibody system that cross reacts with hepatitis B core antigen and antibody.
Non-a, non-b hepatitis: identification of hepatitis-B-like virus particles in serum and liver.
Nucleoside/nucleotide analogues in the treatment of chronic hepatitis B.
Observations on the core particle of hepatitis B virus and the DNA polymerase associated with hepatitis B antigen.
Patterns of antigen expression in hepatoblastoma and hepatocellular carcinoma in childhood.
Peroxidase-anti-peroxidase detection of hepatitis B surface and core antigen in liver biopsy specimens from patients with chronic type B hepatitis.
Phosphonoformic acid-inhibitable nucleotide incorporation as a measure of hepatitis B viral DNA polymerase activity.
Pilot study of recombinant human alpha-interferon for chronic type B hepatitis.
Pilot study of ribavirin and interferon-beta for chronic hepatitis B.
Placebo-controlled trial of recombinant alpha 2-interferon in Chinese HBsAg-carrier children.
Pradefovir Treatment in Patients with Chronic Hepatitis B: Week 24 Results from a Multicenter, Double-blind, Randomized, Noninferiority, Phase 2 Trial.
Preclinical evaluation of group B streptococcal polysaccharide conjugate vaccines prepared with a modified diphtheria toxin and a recombinant duck hepatitis B core antigen.
Prednisone withdrawal followed by recombinant alpha interferon in the treatment of chronic type B hepatitis. A randomized, controlled trial.
Pregenomic RNA encapsidation analysis of eleven missense and nonsense polymerase mutants of human hepatitis B virus.
Preliminary trial of recombinant fibroblast interferon in chronic hepatitis B virus infection.
Preparations of duck hepatitis B virions contain multiple DNA polymerase activities.
Prevalence and heterogeneity of serum DNA polymerase activity in patients with non-A, non-B hepatitis and HBsAg-negative blood donors with elevated SGPT.
Prevalence of HBeAg, anti-HBe and Dane particle-associated DNA polymerase activity in asymptomatic carriers of HBsAg.
Prevalence of hepatitis B virus DNA polymerase mutations in treatment-naïve patients with chronic hepatitis B.
Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China.
Production of hepatitis B virus in vitro by transient expression of cloned HBV DNA in a hepatoma cell line.
Prolonged (6 months) treatment of chronic hepatitis B virus infection with recombinant leukocyte A interferon.
Properties of hepatitis B virus associated DNA polymerase.
Properties of soluble DNA polymerase from sera of hepatitis B virus carriers.
Prospective trial of recombinant leucocyte interferon in chronic hepatitis B: a 10-month follow-up study.
Prospective trial of recombinant leucocyte interferon in chronic hepatitis B: a long-term follow-up study.
Protein phosphatase 1 catalyzes HBV core protein dephosphorylation and is co-packaged with viral pregenomic RNA into nucleocapsids.
Quantitation of hepatitis B viral DNA by solution hybridization: comparison with DNA polymerase and hepatitis B e antigen during antiviral therapy.
Quantitation of hepatitis B virus (HBV) core antigen in serum in the presence of antibodies to HBV core antigen: comparison with assays of serum HBV DNA, DNA polymerase, and HBV e antigen.
Quantitative assay of hepatitis B surface antigen and DNA polymerase activity.
Quantitative correlation between the Dane particle-associated DNA polymerase and the hepatitis B e antigen.
Quantitative relationship between HBeAg and DNA polymerase activity in sera from patients with chronic active hepatitis during a three-month period.
Radioimmunoassay in the detection of the hepatitis B e antigen/antibody system in asymptomatic carriers of hepatitis B surface antigen. Correlation with serum Dane particle associated DNA polymerase activity.
Randomized controlled trial of quinacrine for the treatment of HBsAg-positive chronic hepatitis.
Reactivation of chronic hepatitis B virus infection by cancer chemotherapy.
Reactivation of chronic type B hepatitis presenting as acute viral hepatitis.
Recent advances in the identification of hepatitis viruses.
Receptors for polymerized human serum albumin and other hepatitis B virus markers during acute hepatitis B--predictive value of the outcome of the disease.
Recombinant leukocyte interferon treatment of chronic hepatitis B.
Relation between HBsAg binding with polymerized human serum albumin and HBV replication.
Relation of e antigen to hepatitis B virus infection in an area of hyperendemicity.
Relationship between histology, aminotransferase levels, and viral replication in chronic hepatitis B.
Relationship of the effects of interferon on chronic hepatitis B and the induction of 2',5'-oligoadenylate synthetase.
Release of the hepatitis B virus-associated DNA polymerase from the viral particle by the proteolytic cleavage.
Restriction endonuclease cleavage map and location of unique features of the DNA of hepatitis B virus, subtype adw2.
Restriction endonuclease mapping of the hepatitis B viral genome isolated from Taiwan.
Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.
Review of Laboratory Tests used in Monitoring Hepatitis B Response to Pegylated Interferon and Nucleos(t)ide Analog Therapy.
Risk factors associated with hepatitis B infection in antenatal patients.
RNA interference against hepatitis B virus with endoribonuclease-prepared siRNA despite of the target sequence variations.
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers.
Selection of scFvs specific for HBV DNA polymerase using ribosome display.
Seroconversion from hepatitis B e antigen to antibody in chronic type B hepatitis.
Serum 2',5'-oligoadenylate synthetase activity during interferon treatment of chronic hepatitis B.
Small and large forms of hepatitis B e antigen in the serum: determination by two-site sandwich radioimmunoassay with monoclonal antibodies.
Spontaneous clearance and reactivation of hepatitis B virus infection among male homosexuals with chronic type B hepatitis.
Structure of hepatitis B Dane particle DNA and nature of the endogenous DNA polymerase reaction.
Structure of hepatitis B Dane particle DNA before and after the Dane particle DNA polymerase reaction.
Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.
Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment.
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease.
Suramin inhibits duck hepatitis B virus DNA polymerase activity.
Suramin treatment for chronic active hepatitis B--toxic and ineffective.
Survival in chronic hepatitis B. An analysis of 379 patients.
Tenofovir is a more suitable treatment than entecavir for chronic hepatitis B patients carrying naturally occurring rtM204I mutations.
The changing epidemiology of hepatitis B virus infection in the Canadian north.
The duck hepatitis B virus DNA polymerase is tightly associated with the viral core structure and unable to switch to an exogenous template.
The duck hepatitis B virus polymerase is activated by its RNA packaging signal, epsilon.
The encapsidation signal of hepatitis B virus facilitates preC AUG recognition resulting in inefficient translation of the downstream genes.
The hepatitis B virus and its DNA polymerase: the prototype three-D virus.
The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on antibody responses to routine immunisations given in infancy: Secondary analysis of a randomised controlled trial.
The relationship of hepatitis B e antigen, DNA polymerase activity, and titer of hepatitis B surface antigen with ongoing liver injury in chronic hepatitis B virus infection.
The significance of antibody to hepatitis C virus in patients with chronic hepatitis B.
Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study.
Trans-complementation of the C gene of human and the P gene of woodchuck hepadnaviruses.
Transient antibodies to DNA polymerase in acute hepatitis B and related diseases.
Translation of hepatitis B virus DNA polymerase from the internal AUG codon, not from the upstream AUG codon for the core protein.
Treatment of chronic hepatitis B with recombinant leukocyte interferon and cyanidanol.
Treatment of chronic hepatitis B: focus on telbivudine.
Treatment of chronic type B hepatitis with multiple ten-day courses of adenine arabinoside monophosphate.
Treatment of patients with chronic hepatitis B with adefovir dipivoxil.
Triiodothyronine level and triiodothyronine/thyroxine ratio in HBeAg-positive chronic hepatitis patients treated with prednisolone withdrawal.
Trisodium phosphonoformate inhibits hepatitis B Dane particle DNA polymerase.
Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure.
Understanding Amino Acid Mutations in Hepatitis B Virus Proteins for Rational Design of Vaccines and Drugs.
Vidarabine monophosphate and human leukocyte interferon in chronic hepatitis B infection.
Viral hepatitis type B: propects for active immunization.
Viral hepatitis, type B, DNA polymerase activity and antibody to hepatitis B core antigen.
Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations.
YMDD motif in hepatitis B virus DNA polymerase influences on replication and lamivudine resistance: A study by in vitro full-length viral DNA transfection.
Zidovudine inhibits hepatitis B virus replication.
[Analysis of DNA polymerase reaction products for detecting hepatitis B virus in serum--comparison with spot hybridization technique]
[Change of hepatitis B surface antigen in serum from patients with chronic hepatitis B]
[Hepatitis B virus DNA polymerase activity in various clinical forms of HBV infection]
[Hepatitis B virus DNA polymerase]
[Hepatitis B virus specific DNA polymerase activity as a sensitive marker of viral replication]
[Identification of a virus similar to hepatitis B virus in non-A non-B hepatitis]
[Inhibition of hepatitis B virus associated DNA polymerase by antiviral agents: in vitro studies with clinical implications (author's transl)]
[Markers of viral replication (HBeAg and DNA polymerase activity) in chronic uremia, HBsAg positive, hemodialysis patients]
[Nature, character, occurrence, and demonstration of hepatitis B antigens (author's transl)]
[Screening and cloning of the genes of protein interacting with the N-terminal protein of hepatitis B virus DNA polymerase by yeast-two hybrid technique]
[Study of inhibition effect of bovine lactoferrin in vitro on hepatitis B surface antigen]
[Study of inhibition effect of zinc-, iron- and manganese-saturated bovine lactoferrin on hepatitis B virus DNA in vitro]
[Surface antigen (HBsAg) and core antibody (anti-HBc) in chronic uremia during periodic hemodialysis treatment of hepatitis B patients. Correlation with viral replication markers (HBeAg and DNA polymerase activity)]
[The inhibitory effects of catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and DNA polymerases]
[Treatment of acute hepatitis B with deoxyribonuclease]
[Use of muramyl dipeptides in models of synthetic vaccines]
[Usefulness of the determination of DNA polymerase activity of hepatitis B virus in chronic HBsAg carriers]
Hepatitis B, Chronic
Acute flares in chronic hepatitis B: the natural and unnatural history of an immunologically mediated liver disease.
Acyclovir enhances the antiviral effect of interferon in chronic hepatitis B.
Addition of nucleoside analogues to peg-IFN?-2a enhances virological response in chronic hepatitis B patients without early response to peg-IFN?-2a: a randomized controlled trial.
Antiviral drugs for viruses other than human immunodeficiency virus.
Chronic hepatitis B: What should be the goal for new therapies?
Combination therapy of glycyrrhizin withdrawal and human fibroblast interferon for chronic hepatitis B.
Comparison of serum hepatitis B virus replication markers in patients with chronic hepatitis B: studies on HBeAg/anti-HBe system, viral DNA polymerase and HBV-DNA.
Detection of hepatitis B virus variants resistant to lamivudine and famciclovir among randomly selected chronic carriers from Spain.
Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy.
Efficacy of famciclovir treatment in chronic hepatitis B patients with different mutations at position 552 of the DNA polymerase gene.
Entecavir for chronic hepatitis B: a review.
Have the starting lineup of five for HBV cccDNA synthesis been identified?
Identification of more than one mutation in the hepatitis B virus polymerase gene arising during prolonged lamivudine treatment.
Long-term outcomes and dynamics of mutants associated with Lamivudine-adefovir rescue therapy in patients with lamivudine-resistant chronic hepatitis B.
Mimicry between the hepatitis B virus DNA polymerase and the antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis B virus infection.
Oxethazaine inhibits HBV capsid assembly by blocking the cytosolic calcium signalling pathway.
Prevalence of hepatitis B virus DNA polymerase mutations in treatment-naïve patients with chronic hepatitis B.
Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China.
Prospective trial of recombinant leucocyte interferon in chronic hepatitis B: a 10-month follow-up study.
Prospective trial of recombinant leucocyte interferon in chronic hepatitis B: a long-term follow-up study.
Relationship of the effects of interferon on chronic hepatitis B and the induction of 2',5'-oligoadenylate synthetase.
Serum and urinary neopterin levels in patients with chronic active hepatitis B treated with interferon.
Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids.
Tenofovir is a more suitable treatment than entecavir for chronic hepatitis B patients carrying naturally occurring rtM204I mutations.
The relationship of hepatitis B e antigen, DNA polymerase activity, and titer of hepatitis B surface antigen with ongoing liver injury in chronic hepatitis B virus infection.
Therapeutic strategies for a functional cure of chronic hepatitis B virus infection.
Tolerability of treatments for viral hepatitis.
Vidarabine monophosphate and human leukocyte interferon in chronic hepatitis B infection.
Hepatitis C
Antilactoferrin antibodies in autoimmune liver diseases.
Camel lactoferrin markedly inhibits hepatitis C virus genotype 4 infection of human peripheral blood leukocytes.
Characterization of antiviral activity of lactoferrin against hepatitis C virus infection in human cultured cells.
Comparative study of conventional and novel strategies for the detection of hepatitis C virus RNA in serum: amplicor, branched-DNA, NASBA and in-house PCR.
Detection of lactoferrin in the neutrophils and plasma of the patients suffering from hepatitis C.
Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin.
Effectiveness of human, camel, bovine and sheep lactoferrin on the hepatitis C virus cellular infectivity: comparison study.
Helical peptides derived from lactoferrin bind hepatitis C virus envelope protein E2.
Hepatitis C epitopes from phage-displayed cDNA libraries and improved diagnosis with a chimeric antigen.
Hepatitis C virus envelope proteins bind lactoferrin.
Hepatitis C virus quasispecies in cancerous and noncancerous hepatic lesions: the core protein-encoding region.
Immunofluorescence to Monitor the Cellular Uptake of Human Lactoferrin and its Associated Antiviral Activity Against the Hepatitis C Virus.
Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions.
Inhibitory effects of native and recombinant full-length camel lactoferrin and its N and C lobes on hepatitis C virus infection of Huh7.5 cells.
Lactoferrin inhibits hepatitis B virus infection in cultured human hepatocytes.
Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b.
Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study.
Lactoferrin markedly inhibits hepatitis C virus infection in cultured human hepatocytes.
Long-term follow-up of chronic hepatitis C patients treated with oral lactoferrin for 12 months.
Randomized, double-blind, placebo-controlled trial of bovine lactoferrin in patients with chronic hepatitis C.
Screening the anti infectivity potentials of native N- and C-lobes derived from the camel lactoferrin against hepatitis C virus.
Tandem repeats of lactoferrin-derived anti-hepatitis C virus peptide enhance antiviral activity in cultured human hepatocytes.
Hepatitis C, Chronic
A randomized controlled trial of consensus interferon with or without lactoferrin for chronic hepatitis C patients with genotype 1b and high viral load.
Decreased tear lactoferrin concentration in patients with chronic hepatitis C.
Dose-response trial of lactoferrin in patients with chronic hepatitis C.
Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin.
Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b.
Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study.
Lactoferrin inhibits lipid peroxidation in patients with chronic hepatitis C.
Liposomal lactoferrin induced significant increase of the interferon-alpha (IFN-alpha) producibility in healthy volunteers.
Long-term follow-up of chronic hepatitis C patients treated with oral lactoferrin for 12 months.
Randomized placebo-controlled trial of interferon alpha-2b plus ribavirin with and without lactoferrin for chronic hepatitis C.
Randomized, double-blind, placebo-controlled trial of bovine lactoferrin in patients with chronic hepatitis C.
Use of lactoferrin for chronic hepatitis C.
[Phlebotomy, dietary iron restriction therapy and bovine lactoferrin therapy for chronic hepatitis C]
[Recent advances of basic research and clinical application of lactoferrin as an antiviral reagent against chronic hepatitis C]
Hepatitis E
Hepatitis E vaccine candidate harboring a non-particulate immunogen of E2 fused with CRM197 fragment A.
Woodchuck hepatitis virus: experimental infection and natural occurrence.
Hepatitis, Chronic
A PCR-RFLP based protocol for the detection of hepatitis B virus variants in some lamivudine-untreated chronic hepatitis B virus carriers in Pakistan.
Changes in hepatitis B virus DNA polymerase in relation to the outcome of acute hepatitis type B.
Chronic hepatitis. Aetiology and current management.
Clinical and serological events accompanying changes in hepatitis B viral replication: case reports.
Clinicopathological response of HBsAg-positive chronic active hepatitis to adenine arabinoside: lack of correlation with DNA polymerase response.
Dane particle-associated DNA polymerase and e antigen: relation to chronic hepatitis among carriers of hepatitis B surface antigen.
Differential effects of fibroblast and leucocyte interferon in HBsAg positive chronic active hepatitis.
e antigen and antibody, DNA polymerase, and inhibitors of DNA polymerase in acute and chronic hepatitis.
Early lesions and development of primary hepatocellular carcinoma in man--association with hepatitis B viral infection.
Effects of human recombinant interleukin 2 in patients with chronic hepatitis B: a preliminary report.
Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B.
Failure to detect naturally occurring serum inhibitors of hepatitis B virus deoxyribonucleic acid polymerase.
Fibroblast interferon treatment of a patient with chronic active hepatitis. Increased number of circulating T lymphocytes and elimination of rosette-inhibitory factor.
Immunohistochemical evidence of lactoferrin in hepatic biopsies of patients with viral or cryptogenetic chronic liver disease.
Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study.
Lactoferrin markedly inhibits hepatitis C virus infection in cultured human hepatocytes.
Long-term follow-up of chronic hepatitis patients with HBsAg, HBeAg and Dane particles associated DNA polymerase in serum.
Prolonged (6 months) treatment of chronic hepatitis B virus infection with recombinant leukocyte A interferon.
Quantitative relationship between HBeAg and DNA polymerase activity in sera from patients with chronic active hepatitis during a three-month period.
Resveratrol in Hepatitis C Patients Treated with Pegylated-Interferon-?-2b and Ribavirin Reduces Sleep Disturbance.
Suramin treatment for chronic active hepatitis B--toxic and ineffective.
Transient antibodies to DNA polymerase in acute hepatitis B and related diseases.
Triiodothyronine level and triiodothyronine/thyroxine ratio in HBeAg-positive chronic hepatitis patients treated with prednisolone withdrawal.
[Change of hepatitis B surface antigen in serum from patients with chronic hepatitis B]
[Delta infection in HBsAg carriers]
[Hepatitis B virus DNA polymerase activity in various clinical forms of HBV infection]
[Recent advances of basic research and clinical application of lactoferrin as an antiviral reagent against chronic hepatitis C]
[Significance of the expression of pre-S proteins in mononuclear blood cells in chronic hepatitis caused by the hepatitis B virus]
[Viral replication, histologic damage and enzymatic activity in chronic hepatopathies caused by B virus. Analysis of 21 patients]
Hepatoblastoma
Hepatocyte nuclear factor-4 controls transcription from a TATA-less human sex hormone-binding globulin gene promoter.
The peptide encoded by a novel putative lncRNA HBVPTPAP inducing the apoptosis of hepatocellular carcinoma cells by modulating JAK/STAT signaling pathways.
Hernia, Umbilical
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure.
Herpes Genitalis
Poor correlation between genital lesions and detection of herpes simplex virus in women in labor.
Herpes Simplex
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
3' to 5' exonuclease activity of herpes simplex virus type 1 DNA polymerase modulates its strand displacement activity.
9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.
A colorimetric assay for high-throughput screening of inhibitors of herpes simplex virus type 1 alkaline nuclease.
A DNA topoisomerase activity copurifies with the DNA polymerase induced by herpes simplex virus.
A double-blind, randomized, placebo-controlled trial of acyclovir in late pregnancy for the reduction of herpes simplex virus shedding and cesarean delivery.
A Finger Domain Mutation Affects Enzyme Activity, DNA Replication Efficiency, And Fidelity of an Exonuclease-Deficient DNA Polymerase of Herpes Simplex Virus Type 1.
A functional interaction of ICP8, the herpes simplex virus single-stranded DNA-binding protein, and the helicase-primase complex that is dependent on the presence of the UL8 subunit.
A helix-destabilising protein from herpes simplex virus type I infected cells which specifically stimulates the virus induced DNA polymerase activity in vitro.
A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice.
A monoclonal antibody that neutralizes Epstein-Barr virus, human cytomegalovirus, human herpesvirus 6, and bacteriophage T4 DNA polymerases.
A mutation in the DNA polymerase accessory factor of herpes simplex virus 1 restores viral DNA replication in the presence of raltegravir.
A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.
A novel protein tag from herpes simplex virus type 1 DNA polymerase.
A point mutation within a distinct conserved region of the herpes simplex virus DNA polymerase gene confers drug resistance.
A point mutation within conserved region VI of herpes simplex virus type 1 DNA polymerase confers altered drug sensitivity and enhances replication fidelity.
A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin.
A study of the viral etiology of histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease).
Acute skin eruptions that are positive for herpes simplex virus DNA polymerase in patients with stem cell transplantation: a new manifestation within the erythema multiforme reactive dermatoses.
Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase.
Acyclovir-resistant herpes simplex virus infection due to altered DNA polymerase.
Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities.
Alkaline deoxyribonuclease induced by herpes simplex virus type 1: composition and properties of the purified enzyme.
Alkaline DNase activity in cells infected with a temperature-sensitive mutant of herpes simplex virus type 2.
Alkaline nuclease activity in cells infected with herpes simplex virus type 1 (HSV-1) and HSV-1 temperature-sensitive mutants.
Allosteric interaction of a herpes simplex viral thymidine kinase with host DNA polymerase alpha in mouse LP1-1 cells.
Amplification and characterization of herpesvirus DNA in cerebrospinal fluid from patients with acute encephalitis.
An altered spectrum of herpes simplex virus mutations mediated by an antimutator DNA polymerase.
An importin alpha/beta-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus.
Analysis of in vitro activities of herpes simplex virus type 1 UL42 mutant proteins: correlation with in vivo function.
Analysis of nucleotide sequence variations in herpes simplex virus types 1 and 2, and varicella-zoster virus.
Analysis of the transcript of the herpes simplex virus DNA polymerase gene provides evidence that polymerase expression is inefficient at the level of translation.
Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Antiviral activity of ovotransferrin derived peptides.
Aphidicolin resistance in herpes simplex virus type 1 appears to alter substrate specificity in the DNA polymerase.
Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site.
Application of hydroxylamine hydrochloride for post-PCR sterilization.
Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations.
Association between the herpes simplex virus major DNA-binding protein and alkaline nuclease.
Association between the herpes simplex virus-1 DNA polymerase and uracil DNA glycosylase.
B family DNA polymerases asymmetrically recognize pyrimidines and purines.
Bacteriophage T4 DNA polymerase mutations that confer sensitivity to the PPi analog phosphonoacetic acid.
Bipartite DNA-binding region of the Epstein-Barr virus BMRF1 product essential for DNA polymerase accessory function.
Bovine lactoferrin and lactoferricin interfere with intracellular trafficking of Herpes simplex virus-1.
Bovine lactoferrin peptidic fragments involved in inhibition of herpes simplex virus type 1 infection.
Bovine lactoferrin prevents the entry and intercellular spread of herpes simplex virus type 1 in Green Monkey Kidney cells.
Cancer-selective induction of cytotoxicity by tissue-specific expression of targeted trans-splicing ribozyme.
Caution is required for the interpretation of mutations in herpes simplex virus DNA polymerase for resistance to acyclovir.
Characterization of a DNA polymerase mutant of herpes simplex virus from a severely immunocompromised patient receiving acyclovir.
Characterization of an aphidicolin-resistant mutant of herpes simplex virus type 2 which induces an altered viral DNA polymerase.
Characterization of human herpesvirus 8 ORF59 protein (PF-8) and mapping of the processivity and viral DNA polymerase-interacting domains.
Characterization of monoclonal antibodies recognizing amino- and carboxy-terminal epitopes of the herpes simplex virus UL42 protein.
Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed.
Characterization of the DNA polymerase gene of varicella-zoster viruses resistant to acyclovir.
Clinical features, diagnosis, and treatment of erythema multiforme: a review for the practicing dermatologist.
Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2).
Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit.
Cloning, sequencing, and functional characterization of the two subunits of the pseudorabies virus DNA polymerase holoenzyme: evidence for specificity of interaction.
Combined effects of interferon-alpha and acyclovir on herpes simplex virus type 1 DNA polymerase and alkaline DNase.
Comparative proteomics of the Mycobacterium leprae binding protein myelin P0: its implication in leprosy and other neurodegenerative diseases.
Comparison of DNA polymerase activities induced by herpes simplex virus types 1 and 2.
Comparison of exonucleolytic activities of herpes simplex virus type-1 DNA polymerase and DNase.
Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding.
Contribution of the 3'- to 5'-exonuclease activity of herpes simplex virus type 1 DNA polymerase to the fidelity of DNA synthesis.
Coordinated leading and lagging strand DNA synthesis by using the herpes simplex virus 1 replication complex and minicircle DNA templates.
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.
Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
Crystal Structure of the Cytomegalovirus DNA Polymerase Subunit UL44 in Complex with the C Terminus from the Catalytic Subunit: DIFFERENCES IN STRUCTURE AND FUNCTION RELATIVE TO UNLIGANDED UL44.
Crystal structure of the herpes simplex virus 1 DNA polymerase.
Database on natural polymorphisms and resistance-related non-synonymous mutations in thymidine kinase and DNA polymerase genes of herpes simplex virus types 1 and 2.
Deletions of the carboxy terminus of herpes simplex virus type 1 UL42 define a conserved amino-terminal functional domain.
Demonstration of a stimulatory protein for virus-specified DNA polymerase in phorbol ester-treated Epstein-Barr virus-carrying cells.
Deoxyribonuclease I sensitivity of plasmid genomes in teratocarcinoma-derived stem and differentiated cells.
Deoxyribonucleases in herpes simplex virus type 1 and 2 infected primary rabbit kidney cells.
Detection of active cytomegalovirus infection in inflammatory aortic aneurysms with RNA polymerase chain reaction.
Detection of herpes simplex viral DNA in the iridocorneal endothelial syndrome.
Detection of pathogens causing genital ulcer disease by multiplex polymerase chain reaction.
Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions.
Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness.
Differences in the capacity of two herpes simplex virus isolates to spread from eye to brain map to 1610 base pairs of DNA found in the gene for DNA polymerase.
Differential inhibition of mammalian DNA polymerases alpha, beta and gamma and herpes simplex virus-induced DNA polymerase by the 5'-triphosphates of arabinosyladenine and arabinosylcytosine.
Differential mutation patterns in thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 clones passaged in the presence of acyclovir or penciclovir.
Differential substrate specificity of DNA polymerase beta and of a DNA polymerase induced by herpes simplex virus type 2 towards thymidine triphosphate analogues.
DNA and protein interactions of the small subunit of herpes simplex virus type 1 DNA polymerase.
DNA binding properties and processive proofreading of herpes simplex virus type 1 DNA polymerase.
DNA polymerase in nuclei isolated from herpes simplex virus type-2-infected cells. Characterization of the reaction product and inhibition by substrate analogs.
DNA polymerase in pseudorabies virus infected cells.
DNA polymerase induction by DNA-negative temperature-sensitive mutants of herpes simplex virus type 2.
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein.
DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants.
DNA-binding protein associated with herpes simplex virus DNA polymerase.
Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids.
Effect of herpes simplex virus type 1 infection on the cellular DNA polymerase activities of mouse cell cultures.
Effect of manganese on in vitro replication of damaged DNA catalyzed by the herpes simplex virus type-1 DNA polymerase.
Effect of phosphorothioate homo-oligodeoxynucleotides on herpes simplex virus type 2-induced DNA polymerase.
Effect of spermine on the activity of herpes simplex virus type 1 DNA polymerase: influence of the template.
Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.
Effects of exonuclease activity and nucleotide selectivity of the herpes simplex virus DNA polymerase on the fidelity of DNA replication in vivo.
Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity.
Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis.
Emodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures.
Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition.
Enhanced delivery of exogenous peptides into the class I antigen processing and presentation pathway.
Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells.
Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity.
Epitope mapping and functional characterization of monoclonal antibodies specific for herpes simplex virus type I DNA polymerase.
Evidence against a simple tethering model for enhancement of herpes simplex virus DNA polymerase processivity by accessory protein UL42.
Evidence for control of herpes simplex virus mutagenesis by the viral DNA polymerase.
Evidence that the gene for herpes simplex virus type 1 DNA polymerase accounts for the capacity of an intertypic recombinant to spread from eye to central nervous system.
Evidence that the nuclease activities associated with the herpes simplex type 1 DNA polymerase are due to the 3'-5' exonuclease.
Exonuclease-deficient polymerase mutant of herpes simplex virus type 1 induces altered spectra of mutations.
Expression analysis of recombinant herpes simplex virus type 1 DNase.
Expression kinetics of the late UL12 gene encoding the bovine herpesvirus 1 alkaline nuclease.
Expression of herpes simplex virus DNA fragments located in epidermal keratinocytes and germinative cells is associated with the development of erythema multiforme lesions.
Expression of herpes simplex virus type 1 DNA polymerase by recombinant vaccinia virus.
Expression of herpes simplex virus type 1 DNA polymerase gene by in vitro translation and effects of gene deletions on activity.
Expression of herpes simplex virus type 1 DNA polymerase in Saccharomyces cerevisiae and detection of virus-specific enzyme activity in cell-free lysates.
Expression of the Epstein-Barr virus DNA polymerase in Escherichia coli for use as antigen for the diagnosis of nasopharyngeal carcinoma.
Expression, purification, and characterization of the herpes simplex virus type-1 DNA polymerase.
Fever and bulging fontanelle mimicking meningitis in an infant diagnosed with benign intracranial hypertension.
Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus.
Functional conservations of the alkaline nuclease of herpes simplex type 1 and human cytomegalovirus.
Functional expression of a cloned herpes simplex virus type 1 DNA polymerase gene.
Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.
Gene polymorphism of thymidine kinase and DNA polymerase in clinical strains of herpes simplex virus.
Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.
Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1.
Genomic localization and sequence analysis of the putative bovine herpesvirus-1 DNA polymerase gene.
Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene.
Genotypic characterization of herpes simplex virus DNA polymerase UL42 processivity factor.
Genotypic characterization of the DNA polymerase and sensitivity to antiviral compounds of foscarnet-resistant herpes simplex virus type 1 (HSV-1) derived from a foscarnet-sensitive HSV-1 strain.
Genotypic characterization of UL23 thymidine kinase and UL30 DNA polymerase of clinical isolates of herpes simplex virus: natural polymorphism and mutations associated with resistance to antivirals.
Glycosaminoglycans are not indispensable for the anti-herpes simplex virus type 2 activity of lactoferrin.
Heat-sensitive deoxyribonuclease activity in cells infected with herpes simplex virus.
Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation.
Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus.
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-?-induced NF-?B activation by interacting with p65/RelA and p50/NF-?B1.
Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3'-to-5' Direction and Is Dependent on the 3'-to-5' Exonuclease Active Site.
Herpes simplex virus associated erythema multiforme (HAEM) is mechanistically distinct from drug-induced erythema multiforme: interferon-gamma is expressed in HAEM lesions and tumor necrosis factor-alpha in drug-induced erythema multiforme lesions.
Herpes simplex virus DNA in occult lesions: demonstration by the polymerase chain reaction.
Herpes simplex virus DNA polymerase as the site of phosphonoacetate sensitivity: temperature-sensitive mutants.
Herpes simplex virus DNA polymerase, thymidine kinase and deoxyribonuclease activities in cells infected with wild type, ultraviolet-irradiated and defective virus.
Herpes simplex virus DNA synthesis in a partially purified soluble extract from infected cells.
Herpes simplex virus gene expression in neurons: viral DNA synthesis is a critical regulatory event in the branch point between the lytic and latent pathways.
Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease.
Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin.
Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis.
Herpes simplex virus non-structural proteins. IV. Purification of the virus-induced deoxyribonuclease and characterization of the enzyme using monoclonal antibodies.
Herpes simplex virus processivity factor UL42 imparts increased DNA-binding specificity to the viral DNA polymerase and decreased dissociation from primer-template without reducing the elongation rate.
Herpes simplex virus resistance and sensitivity to phosphonoacetic acid.
Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates.
Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition.
Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus.
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate.
Herpes simplex virus type 1 DNA polymerase. Mechanism-based affinity chromatography.
Herpes simplex virus type 1 DNA polymerase. Mutational analysis of the 3'-5'-exonuclease domain.
Herpes simplex virus type 1 single-strand DNA binding protein ICP8 enhances the nuclease activity of the UL12 alkaline nuclease by increasing its processivity.
Herpes simplex virus type I DNA polymerase. Kinetic properties of the associated 3'-5' exonuclease activity and its role in araAMP incorporation.
Herpes simplex virus UL12.5 targets mitochondria through a mitochondrial localization sequence proximal to the N terminus.
Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine.
Herpes simplex-1 DNA polymerase. Identification of an intrinsic 5'----3' exonuclease with ribonuclease H activity.
Herpesvirus proteins: DNA polymerase and pyrimidine deoxynucleoside kinase activities in temperature-sensitive mutants of herpes simplex virus type 2.
Heterogeneity and evolution of thymidine kinase and DNA polymerase mutants of herpes simplex virus type 1: implications for antiviral therapy.
High conservation of herpes simplex virus UL5/UL52 helicase-primase complex in the era of new antiviral therapies.
Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion.
HSV- and chemical carcinogen-induced amplification of SV40 DNA sequences in transformed cells is cell-line-dependent.
HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression.
Human DNA polymerase alpha: predicted functional domains and relationships with viral DNA polymerases.
Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes.
Identification of a pseudorabies virus UL12 (deoxyribonuclease) gene.
Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication.
Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.
Identification of crucial hydrogen-bonding residues for the interaction of herpes simplex virus DNA polymerase subunits via peptide display, mutational, and calorimetric approaches.
Identification of the herpes simplex virus DNA polymerase gene.
Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by Herpes Simplex Virus I DNA polymerase.
Immunogenicity versus pathogenicity after anterior chamber inoculation of an acyclovir-induced double mutant of HSV-1.
Immunological evidence for a specific DNA polymerase produced after infection by herpes simplex virus.
Impact of Amino Acid Substitutions in Region II and Helix K of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Resistance to Foscarnet.
Impaired mismatch extension by a herpes simplex DNA polymerase mutant with an editing nuclease defect.
In situ detection of alkaline nuclease activity in cells infected with herpes simplex virus type 1 (HSV-1).
In situ DNA PCR and RNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice.
In vitro activities of penciclovir and acyclovir against herpes simplex virus types 1 and 2.
In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme.
In vitro processing of herpes simplex virus type 1 DNA replication intermediates by the viral alkaline nuclease, UL12.
Induction of deoxyribonucleic acid polymerase and deoxyribonuclease activities in cells infected with herpes simplex virus type II.
Induction of Epstein-Barr virus-associated DNA polymerase by 12-O-tetradecanoylphorbol-13-acetate. Purification and characterization.
Inhibition by interferon of herpes simplex virus thymidine kinase and DNA polymerase in infected and biochemically transformed cells.
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U.
Inhibition of DNA Polymerase from Herpes Simplex Virus-Infected Wi-38 Cells by Phosphonoacetic Acid.
Inhibition of Epstein-Barr virus infection by lactoferrin.
Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues.
Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates.
Inhibition of herpes simplex virus infection by lactoferrin is dependent on interference with the virus binding to glycosaminoglycans.
Inhibition of herpes simplex virus type 1 DNA polymerase activity by peptides from the UL42 accessory protein is largely nonspecific.
Inhibition of herpes simplex virus type 1 DNA polymerase by the natural product oosporein.
Inhibition of herpes simplex virus type 1 DNA polymerase by [1R(1 alpha,2 beta,3 alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl] guanine.
Inhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral DNA Replication by 9-(2-Hydroxyethoxymethyl) guanine and Its Triphosphate.
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate.
Inhibition of herpes simplex virus-induced DNA polymerase, cellular DNA polymerase alpha, and virus production by aphidicolin.
Inhibition of HSV cell-to-cell spread by lactoferrin and lactoferricin.
Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit.
Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.
Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript.
Inhibition with lactoferrin of in vitro infection with human herpes virus.
Inhibitory effects of triphosphate derivatives of oxetanocin G and related compounds on eukaryotic and viral DNA polymerases and human immunodeficiency virus reverse transcriptase.
Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha.
Interaction between the DNA polymerase and single-stranded DNA-binding protein (infected cell protein 8) of herpes simplex virus 1.
Interaction between the herpes simplex virus type 1 origin-binding and DNA polymerase accessory proteins.
Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model primer template.
Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate.
Interaction of the mouse chromosomal protein HMG-I with the 3' ends of genes in vitro.
Interaction with nucleic acids and stimulation of the viral DNA polymerase by the herpes simplex virus type 1 major DNA-binding protein.
Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin.
Intranuclear localization of herpes simplex virus immediate-early and delayed-early proteins: evidence that ICP 4 is associated with progeny virus DNA.
Intratypic variability of a tandem repeat locus within the DNA polymerase gene of human herpes simplex virus type 2.
Involvement of bovine lactoferrin moieties in the inhibition of herpes simplex virus type 1 infection.
Involvement of DNA polymerase alpha in host cell reactivation of UV-irradiated herpes simplex virus.
Involvement of eucaryotic deoxyribonucleic acid polymerases alpha and gamma in the replication of cellular and viral deoxyribonucleic acid.
Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus.
Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymerase.
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 "- (4"-amino-1",2"-oxathiole-2",2"-dioxide)thymine (TSAO-T).
Lactoferricin but not lactoferrin inhibit herpes simplex virus type 2 infection in mice.
Lactoferrin and lactoferricin inhibit Herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir.
Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis.
Lactoferrin inhibits herpes simplex virus type 1 adsorption to Vero cells.
Lactoferrin inhibits herpes simplex virus type-1 (HSV-1) infection to mouse cornea.
Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease.
Linear diffusion on DNA despite high-affinity binding by a DNA polymerase processivity factor.
Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase.
Localization of the herpes simplex virus type 1 65-kilodalton DNA-binding protein and DNA polymerase in the presence and absence of viral DNA synthesis.
Mechanism of inhibition of human cytomegalovirus replication by oxetanocin G.
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites.
Mechanisms of immunization against cancer using chimeric antigens.
Mechanisms of inhibition of herpes simplex virus type 2 growth by 28-mer phosphorothioate oligodeoxycytidine.
Metabolism and mode of action of (R)-9-(3,4-dihydroxybutyl)guanine in herpes simplex virus-infected vero cells.
Metal complexes of bovine lactoferrin inhibit in vitro replication of herpes simplex virus type 1 and 2.
Mitochondrial Nucleases ENDOG and EXOG Participate in Mitochondrial DNA Depletion Initiated by Herpes Simplex Virus 1 UL12.5.
Mode of inhibition of herpes simplex virus DNA polymerase by phosphonoacetate.
Mutants of herpes simplex virus types 1 and 2 that are resistant to phosphonoacetic acid induce altered DNA polymerase activities in infected cells.
Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine.
Mutational analysis of DNA polymerase substrate recognition and subunit interactions using herpes simplex virus as prototype.
Mutations in the C terminus of herpes simplex virus type 1 DNA polymerase can affect binding and stimulation by its accessory protein UL42 without affecting basal polymerase activity.
Mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene can confer altered drug sensitivities.
Mutations in the Herpes Simplex Virus DNA Polymerase Gene Can Confer Resistance to 9-?-d-Arabinofuranosyladenine.
Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine.
Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin.
Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors.
Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication.
Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42.
Mutations within conserved motifs in the 3'-5' exonuclease domain of herpes simplex virus DNA polymerase.
Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates.
ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase.
Neurovirulence and latency of drug-resistant clinical herpes simplex viruses in animal models.
Neutralization of purified herpes simplex virus DNA polymerase by two antipeptide sera.
Non-HIV antivirals - a review of the recent patent literature.
Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin A.
Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase.
Novel interaction of aphidicolin with herpes simplex virus DNA polymerase and polymerase-associated exonuclease.
Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient.
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2.
Nuclear import of HSV-1 DNA polymerase processivity factor UL42 is mediated by a C-terminally located bipartite nuclear localization signal.
Nucleolin is required for efficient nuclear egress of herpes simplex virus type 1 nucleocapsids.
Nucleotide sequence of the DNA polymerase gene of herpes simplex virus type 1 strain Angelotti.
Nucleotide sequence of the DNA polymerase gene of herpes simplex virus type 2 and comparison with the type 1 counterpart.
On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase.
Oral lactoferrin prevents body weight loss and increases cytokine responses during herpes simplex virus type 1 infection of mice.
Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.
Persistent infection of a lymphoma cell line by herpes simplex virus.
pH-Dependent conformational changes and topology of a herpesvirus translocating peptide in a membrane-mimetic environment.
Physical and genetic analysis of the herpes simplex virus DNA polymerase locus.
Physical Interaction between the Herpes Simplex Virus Type 1 Exonuclease, UL12, and the DNA double strand break sensing MRN complex.
Physical mapping of drug resistance mutations defines an active center of the herpes simplex virus DNA polymerase enzyme.
Physical mapping of paar mutations of herpes simplex virus type 1 and type 2 by intertypic marker rescue.
Polymerase and exonuclease activities in herpes simplex virus type 1 DNA polymerase are not highly coordinated.
Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.
Potent inhibitory effects of the 5'-triphosphates of (E)-5-(2-bromovinyl)-2'-deoxyuridine and (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on DNA polymerase gamma.
Presence of antibody against herpes simplex virus-specified thymidine kinase and deoxyribonuclease in human sera.
PROCESSING OF LAGGING STRAND INTERMEDIATES IN VITRO BY HERPES SIMPLEX VIRUS TYPE 1 DNA POLYMERASE.
Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase.
Production of antibodies of predetermined specificity against herpes simplex virus DNA polymerase and their use in characterization of the enzyme.
Profile of anti-herpetic action of ASP2151 (amenamevir) as a helicase-primase inhibitor.
Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity?
Promotion of CTL epitope presentation by a nanoparticle with environment-responsive stability and phagolysosomal escape capacity.
Properties of herpes simplex virus DNA polymerase and characterization of its associated exonuclease activity.
Properties of herpes simplex virus type 1 and type 2 DNA polymerase.
Properties of purified enzymes induced by pathogenic drug-resistant mutants of herpes simplex virus. Evidence for virus variants expressing normal DNA polymerase and altered thymidine kinase.
Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties.
Purification of Epstein-Barr virus DNA polymerase from P3HR-1 cells.
Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase.
Pyrophosphate analogues as inhibitors of DNA polymerases of cytomegalovirus, herpes simplex virus and cellular origin.
Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase.
Rapid detection of herpes simplex virus by polymerase chain reaction.
Recombinational hotspots within the herpes simplex virus DNA polymerase gene?
Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.
Related functional domains in virus DNA polymerases.
Replication and recombination of Herpes simplex virus DNA.
Replication, recombination and packaging of amplicon DNA in cells infected with the herpes simplex virus type 1 alkaline nuclease null mutant ambUL12.
Rescue of the adeno-associated virus genome from a plasmid vector: evidence for rescue by replication.
Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locus.
Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci.
Resistance of herpes simplex virus to adenine arabinoside and E-5-(2-bromovinyl)-2'-deoxyuridine: a physical analysis.
Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene.
Resistance testing of clinical herpes simplex virus type 2 isolates collected over 4 decades.
Resistance to antiviral inhibitors caused by the mutation S889A in the highly-conserved 885-GDTDS motif of the herpes simplex virus type 1 DNA polymerase.
Restoration of wild-type pathogenicity to an attenuated DNA polymerase mutant of herpes simplex virus type 1.
Reversible inhibition of the induction of DNA polymerase of herpes simplex virus type 2 in HeLa cells.
Reversion of mutations in the thymidine kinase gene in herpes simplex viruses resistant to phosphonoacetate.
Role of protein-protein interactions during herpes simplex virus type 1 recombination-dependent replication.
Role of the carboxy terminus of herpes simplex virus type 1 DNA polymerase in its interaction with UL42.
Roles of conserved residues within the pre-NH2-terminal domain of herpes simplex virus 1 DNA polymerase in replication and latency in mice.
Rolling circle DNA replication by extracts of herpes simplex virus type 1-infected human cells.
Secondary structure and structure-activity relationships of peptides corresponding to the subunit interface of herpes simplex virus DNA polymerase.
Selection and characterisation of acyclovir-resistant herpes simplex virus type 1 mutants inducing altered DNA polymerase activities.
Selection and preliminary characterization of acyclovir-resistant mutants of varicella zoster virus.
Selective inhibition of herpes simplex virus type 1 DNA polymerase by zinc ions.
Selective virus inhibitors.
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral Resistance.
Sequence analysis of the bovine herpesvirus type 1 genes homologous to the DNA polymerase (UL30), the major DNA-binding protein (UL29) and ICP18.5 assembly protein (UL28) genes of herpes simplex virus.
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.
Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene.
Sequences at the C-terminus of the herpes simplex virus type 1 UL30 protein are dispensable for DNA polymerase activity but not for viral origin-dependent DNA replication.
Single mutations at many sites within the DNA polymerase locus of herpes simplex viruses can confer hypersensitivity to aphidicolin and resistance to phosphonoacetic acid.
Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.
Site-specific mutagenesis of a highly conserved region of the herpes simplex virus type 1 DNA polymerase gene.
Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface.
Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit.
Structural and functional organization of herpes simplex virus DNA polymerase investigated by limited proteolysis.
Structural organization and unusual codon usage in the DNA polymerase gene from herpes simplex virus type 1.
Structural organization of the conserved gene block of Herpesvirus saimiri coding for DNA polymerase, glycoprotein B, and major DNA binding protein.
Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase.
Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III.
Structure--activity relationships of pyrrole amidine antiviral antibiotics. 1. Modifications of the alkylamidine side chain.
Structure-activity relationships of pyrrole amidine antiviral antibiotics. 2. Preparation of mono- and tripyrrole derivatives of congocidine.
Structure-function analysis of the herpes simplex virus type 1 UL12 gene: correlation of deoxyribonuclease activity in vitro with replication function.
Structure-function studies of the herpes simplex virus type 1 DNA polymerase.
Studies on DNA topoisomerases I and II in herpes simplex virus type 2-infected cells.
Studies on the herpes simplex virus alkaline nuclease: detection of type-common and type-specific epitopes on the enzyme.
Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase.
Synthesis and antiherpetic activity of (+/-)-9-[[(Z)-2-(hydroxymethyl)cyclopropyl]methyl]guanine and related compounds.
Synthesis of esters of phosphonoformic acid and their antiherpes activity.
Temperature-sensitive mutants in two distinct complementation groups of herpes simplex virus type 1 specify thermolabile DNA polymerase.
The adeno-associated virus-mediated HSV-TK/GCV suicide system: a potential strategy for the treatment of bladder carcinoma.
The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase.
The C-terminal third of UL42, a HSV-1 DNA replication protein, is dispensable for viral growth.
The catalytic subunit of herpes simplex virus type 1 DNA polymerase contains a nuclear localization signal in the UL42-binding region.
The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex.
The characterization of the EBV alkaline deoxyribonuclease cloned and expressed in E. coli.
The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase.
The Crystal Structure of PF-8, the DNA Polymerase Accessory Subunit from Kaposi's Sarcoma-Associated Herpesvirus.
The deoxyribonuclease induced after infection of KB cells by herpes simplex virus type 1 or type 2. I. Purification and characterization of the enzyme.
The effect of a temperature-sensitive lesion in the alkaline DNase of herpes simplex virus type 2 on the synthesis of viral DNA.
The effect of polyamines on herpes simplex virus type 1 DNA polymerase purified from infected baby hamster kidney cells (BHK-21/C13).
The effect of the UL42 protein on the DNA polymerase activity of the catalytic subunit of the DNA polymerase encoded by herpes simplex virus type 1.
The enhanced DNA replication fidelity of a mutant herpes simplex virus type 1 DNA polymerase is mediated by an improved nucleotide selectivity and reduced mismatch extension ability.
The essential 65-kilodalton DNA-binding protein of herpes simplex virus stimulates the virus-encoded DNA polymerase.
The essential in vivo function of the herpes simplex virus UL42 protein correlates with its ability to stimulate the viral DNA polymerase in vitro.
The exonuclease activity of HSV-1 UL12 is required for in vivo function.
The exonuclease activity of HSV-1 UL12 is required for the production of viral DNA that can be packaged to produce infectious virus.
The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication.
The herpes simplex virus DNA polymerase: analysis of the functional domains.
The herpes simplex virus processivity factor, UL42, binds DNA as a monomer.
The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitro.
The herpes simplex virus type 1 alkaline nuclease is not essential for viral DNA synthesis: isolation and characterization of a lacZ insertion mutant.
The herpes simplex virus type 1 DNA polymerase accessory protein, UL42, contains a functional protease-resistant domain.
The herpes simplex virus type 1 DNA polymerase gene: site of phosphonoacetic acid resistance mutation in strain Angelotti is highly conserved.
The herpes simplex virus type 1 DNA polymerase processivity factor increases fidelity without altering pre-steady-state rate constants for polymerization or excision.
The herpes simplex virus type 1 DNA polymerase processivity factor, UL42, does not alter the catalytic activity of the UL9 origin-binding protein but facilitates its loading onto DNA.
The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity.
The herpes simplex virus type 1 UL8 protein influences the intracellular localization of the UL52 but not the ICP8 or POL replication proteins in virus-infected cells.
The herpes simplex virus type 2 alkaline DNase activity is essential for replication and growth.
The herpes simplex virus type I DNA polymerase. Polypeptide structure and antigenic domains.
The human cytomegalovirus glycoprotein B gene (ORF UL55) is expressed early in the infectious cycle.
The human cytomegalovirus UL44 C clamp wraps around DNA.
The inherent quantitative capacity of the reverse transcription-polymerase chain reaction.
The positively charged surface of herpes simplex virus UL42 mediates DNA binding.
The Pre-NH2-Terminal Domain of the Herpes Simplex Virus 1 DNA Polymerase Catalytic Subunit is Required for Efficient Viral Replication.
The product of a 1.9-kb mRNA which overlaps the HSV-1 alkaline nuclease gene (UL12) cannot relieve the growth defects of a null mutant.
The product of the UL12.5 gene of herpes simplex virus type 1 is a capsid-associated nuclease.
The product of the UL12.5 gene of herpes simplex virus type 1 is not essential for lytic viral growth and is not specifically associated with capsids.
The structure and function of the HSV DNA replication proteins: defining novel antiviral targets.
The UL12.5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus.
The US3 protein kinase of herpes simplex virus type 2 is associated with phosphorylation of the UL12 alkaline nuclease in vitro.
trans-acting requirements for replication of Epstein-Barr virus ori-Lyt.
Translational regulation of herpes simplex virus DNA polymerase.
Two regions of the herpes simplex virus type 1 UL42 protein are required for its functional interaction with the viral DNA polymerase.
Unusual regulation of expression of the herpes simplex virus DNA polymerase gene.
Use of H19 regulatory sequences for targeted gene therapy in cancer.
Use of suppressor analysis to identify DNA polymerase mutations in herpes simplex virus which affect deoxynucleoside triphosphate substrate specificity.
Use of Vibrio spp. for expression of Escherichia coli enterotoxin B subunit fusion proteins: purification and characterization of a chimera containing a C-terminal fragment of DNA polymerase from herpes simplex virus type 1.
Utility of restriction fragment analysis for typing herpes simplex virus amplicons following PCR of targets in the DNA polymerase gene.
Variation of DNA polymerase and RNA polymerase activities in cells infected with herpes simplex virus type 1.
Viral alkaline nuclease in intranuclear dense bodies induced by herpes simplex infection.
Virus particles produced by the herpes simplex virus type 1 alkaline nuclease null mutant ambUL12 contain abnormal genomes.
[Analysis of mutations in DNA polymerase and thymidine kinase genes of herpes simplex virus clinical isolates resistant to antiherpetic drugs]
[Applications of the polymerase chain reaction (PCR) to the diagnosis of central nervous system infections]
[Contribution of the laboratory in case of resistance to acyclovir of herpes simplex and varicella zoster virus]
[Deoxyribonuclease in treatment of recurrent herpes simplex]
[Detection of four human herpesviruses DNA and virus-specific IgM antibody in blood specimens of infants]
[Effect of desoxyribonuclease on herpes simplex virus]
[Herpes simplex virus and its DNA polymerase]
[Inhibition of the reproduction of a herpes simplex I virus carrying mutations in the thymidine kinase and DNA polymerase genes]
[Inhibitory analysis of DNA polymerase of herpes simplex type 1]
[Inhibitory analysis of DNA polymerases from human viruses using modified substrates]
[Inhibitory effect of various analogs of nucleoside-5'-triphosphates on DNA synthesis catalyzed by DNA polymerase from herpes simplex virus type I]
[The inhibitory effects of catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and DNA polymerases]
[The relationship between gene function and virulence in alpha-herpesviruses]
Herpes Zoster
A protein isolated from human oviductal tissue in vitro secretion, identified as human lactoferrin, interacts with spermatozoa and oocytes and modulates gamete interaction.
Antiviral lead compounds from marine sponges.
Antiviral sensitivities of the acute retinal necrosis syndrome virus.
Brivudin (bromovinyl deoxyuridine).
Comparative inhibition of DNA polymerases from varicella zoster virus (TK+ and TK-) strains by (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate.
Detection of herpes simplex viral DNA in the iridocorneal endothelial syndrome.
Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.
Non-HIV antivirals - a review of the recent patent literature.
[A study of the therapeutic effect of deoxyribonuclease in shingles (herpes zoster)]
[Contribution of the laboratory in case of resistance to acyclovir of herpes simplex and varicella zoster virus]
[Intensive therapy of herpes zoster with deoxyribonuclease]
Herpesviridae Infections
Anti-herpesvirus agents: a patent and literature review (2003 to present).
Development of a polymerase chain reaction for the detection of abalone herpesvirus infection based on the DNA polymerase gene.
Identification of gammaherpesvirus infection in free-ranging black bears (Ursus americanus).
Structures and Divergent Mechanisms in Capsid Maturation and Stabilization Following Genome Packaging of Human Cytomegalovirus and Herpesviruses.
Testing the susceptibility of human herpesviruses to antivirals.
Histiocytoma, Malignant Fibrous
Chromatin structure changes suggest a compensatory response to c-myc gene amplification in malignant fibrous histiocytoma.
HIV Infections
Cervicovaginal levels of lactoferrin, secretory leukocyte protease inhibitor, and RANTES and the effects of coexisting vaginoses in human immunodeficiency virus (HIV)-seronegative women with a high risk of heterosexual acquisition of HIV infection.
Comparative evaluation of Amplicor HIV-1 DNA test, version 1.5, by manual and automated DNA extraction methods using venous blood and dried blood spots for HIV-1 DNA PCR testing.
DNA polymerase chain reaction for the diagnosis of vertical HIV infection.
Early detection of HIV infection among Kenyan infants using a reverse transcriptase activity assay.
Epidemiology of HIV infection in the newborn.
Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trial.
Highlights in the development of new antiviral agents.
Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity.
Interactions between HIV and hepatitis B virus in homosexual men: effects on the natural history of infection.
Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa?
Long-term inhibition of clinical and laboratory human immunodeficiency virus strains in human T-cell lines containing an HIV-regulated diphtheria toxin A chain gene.
Mitochondrial DNA depletion in HIV-infected patients with chronic hepatitis C and effect of pegylated interferon plus ribavirin therapy.
Modulation of innate and adaptive immunity by lactoferrin in human immunodeficiency virus (HIV)-infected, antiretroviral therapy-naïve children.
Nonspecific oral immunity in individuals with HIV infection.
Perinatal HIV Status and Executive Function During School-Age and Adolescence: A Comparative Study of Long-Term Cognitive Capacity Among Children From a High HIV Prevalence Setting.
Prevention of Mother-to-Child Transmission and Early Real-Time DNA Polymerase Chain Reaction Results Among HIV-Exposed Infants in Bujumbura, Burundi.
Recent progress in the design of small molecule inhibitors of HIV RNase H.
Salivary lactoferrin in HIV-infected children: correlation with Candida albicans carriage, oral manifestations, HIV infection and its antifungal activity.
Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine.
[Evaluation of the antiradical protector effect of multifermented milk serum with reiterated dosage in rats]
[Iron metabolism and indicators reflecting its changes in pulmonary tuberculosis (literature review).]
[The use of PCR analysis for the diagnosis of HIV infection in infants in the 1st months of life]
Hodgkin Disease
Demonstration of lactoferrin in tumor tissue from two patients with positive gallium scans.
Evidence for multiple forms of DNA polymerase in Hodgkin's disease.
Huntington Disease
A reproducible assay of polymerase chain reaction to detect trinucleotide repeat expansion of Huntington's disease and senile chorea.
DNA polymerase ? promotes CAG•CTG repeat expansions in Huntington's disease via insertion sequences of its catalytic domain.
Hyaline Membrane Disease
Lactoferrin and lysozyme deficiency in airway secretions: association with the development of bronchopulmonary dysplasia.
Hydrocephalus
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.
Hyperalgesia
Effect of prolonged administration of bovine lactoferrin in neuropathic pain: involvement of opioid receptors, nitric oxide and TNF-alpha.
Hypercholesterolemia
Enteric lactoferrin attenuates the development of high-fat and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis in Microminipigs.
Multiple inflammatory markers in patients with significant coronary artery disease.
Hypergammaglobulinemia
Atypical manifestations of pancreatitis with autoimmune phenomenon in an adolescent female.
Hyperglycemia
Blockade of glucagon signaling prevents or reverses diabetes onset only if residual ?-cells persist.
Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes.
Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout.
Immunosuppressive effects of streptozotocin-induced diabetes result in absolute lymphopenia and a relative increase of T regulatory cells.
Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes.
Lactoferrin ameliorates corticosterone-related acute stress and hyperglycemia in rats.
Polysaccharides of a fermented food, natto, suppress sucrose-induced hyperglycemia in an in vivo evaluation system and inhibit glucose uptake by human intestinal cells.
Hyperinsulinism
Troglitazone action is independent of adipose tissue.
Hyperlipidemias
Fat Overload Induces Changes in Circulating Lactoferrin That Are Associated With Postprandial Lipemia and Oxidative Stress in Severely Obese Subjects.
Lactoferrin and its hydrolysate bind directly to the oleate-activated form of the lipolysis stimulated lipoprotein receptor.
Hyperphosphatemia
Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling.
Hyperprolactinemia
Composition of breast fluid of a man with galactorrhea and hyperprolactinaemia.
Milk protein concentrations in galactorrhoeic mammary secretions.
Hypersensitivity
8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.
A 140-bp AT-rich sequence mediates positive and negative transcriptional control of a Plasmodium falciparum developmentally regulated promoter.
A 3' enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult beta-globin gene.
A bisanthracycline (WP631) represses uPAR gene expression and cell migration of RKO colon cancer cells by interfering with transcription factor binding to a chromatin-accessible -148/-124 promoter region.
A boundary for histone acetylation allows distinct expression patterns of the Ad4BP/SF-1 and GCNF loci in adrenal cortex cells.
A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development.
A CD8 genomic fragment that directs subset-specific expression of CD8 in transgenic mice.
A close association between sites of DNase I hypersensitivity and sites of enhanced cleavage by micrococcal nuclease in the 5'-flanking region of the actively transcribed ovalbumin gene.
A comparative encyclopedia of DNA elements in the mouse genome.
A consensus set of genetic vulnerabilities to ATR inhibition.
A critical role for heat shock transcription factor in establishing a nucleosome-free region over the TATA-initiation site of the yeast HSP82 heat shock gene.
A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison.
A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2.
A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation.
A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity.
A far upstream cis-element is required for Wilms' tumor-1 (WT1) gene expression in renal cell culture.
A G-Box-Like Motif Is Necessary for Transcriptional Regulation by Circadian Pseudo-Response Regulators in Arabidopsis.
A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function.
A kappaB-related binding site is an integral part of the mts1 gene composite enhancer element located in the first intron of the gene.
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.
A MARTX Toxin rtxA Gene Is Controlled by Host Environmental Signals through a CRP-Coordinated Regulatory Network in Vibrio vulnificus.
A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data.
A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.
A novel DNA sequence motif in human and mouse genomes.
A novel duplication of PRMD13 causes North Carolina macular dystrophy: overexpression of PRDM13 orthologue in drosophila eye reproduces the human phenotype.
A novel method for discovering local spatial clusters of genomic regions with functional relationships from DNA contact maps.
A novel tandem duplication of PRDM13 in a Chinese family with North Carolina macular dystrophy.
A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice.
A quantitative analysis of the impact on chromatin accessibility by histone modifications and binding of transcription factors in DNase I hypersensitive sites.
A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice.
A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes.
A retinoic acid/cAMP-responsive enhancer containing a cAMP responsive element is required for the activation of the mouse thrombomodulin-encoding gene in differentiating F9 cells.
A Silencer-Proximal Intronic Region Is Required for Sustained CD4 Expression in Postselection Thymocytes.
A splice-site variant in the lncRNA gene RP1-140A9.1 cosegregates in the large Volkmann cataract family.
A stage-specific enhancer of immunoglobulin J chain gene is induced by interleukin-2 in a presecretor B cell stage.
A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter.
A Th2 cytokine LCR. Adding a new piece to the regulatory puzzle.
A transcription-dependent DNase I-hypersensitive site in a far upstream segment of the chicken alpha-globin gene domain coincides with a matrix attachment region.
A tyrosine hydroxylase-yellow fluorescent protein knock-in reporter system labeling dopaminergic neurons reveals potential regulatory role for the first intron of the rodent tyrosine hydroxylase gene.
ABCC6 Expression Is Regulated by CCAAT/Enhancer-Binding Protein Activating a Primate-Specific Sequence Located in the First Intron of the Gene.
Accurate prediction of inducible transcription factor binding intensities in vivo.
AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening.
Actinomycin D induced DNase I hypersensitivity and asymmetric structure transmission in a DNA hexadecamer.
Activation of the erythropoietin gene due to the proximity of an expressed gene.
Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells.
Active transcription of the human FASL/CD95L/TNFSF6 promoter region in T lymphocytes involves chromatin remodeling: role of DNA methylation and protein acetylation suggest distinct mechanisms of transcriptional repression.
Adjuvant Allergen Fusion Proteins as Novel Tools for the Treatment of Type I Allergies.
Albumin and alpha-fetoprotein gene transcription in rat hepatoma cell lines is correlated with specific DNA hypomethylation and altered chromatin structure in the 5' region.
Aldosterone alters the chromatin structure of the murine endothelin-1 gene.
All-Trans Retinoic Acid Induces Chromatin Remodeling at the Promoter of the Mouse Liver, Bone, and Kidney Alkaline Phosphatase Gene in C3H10T 1/2 Cells.
Allele-specific chromatin remodeling of the tumor necrosis factor-alpha promoter.
Alterations in chromatin structure associated with glucocorticoid-induced expression of endogenous mouse mammary tumor virus genes.
Alterations in globin gene chromatin conformation during murine erythroleukemia cell differentiation.
Alterations in local chromatin structure accompany thyroid hormone induction of growth hormone gene transcription.
Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene.
Alternative sets of DNase I-hypersensitive sites characterize the various functional states of the chicken lysozyme gene.
An autoregulatory enhancer controls mammary-specific STAT5 functions.
An enhancer/locus control region is not sufficient to open chromatin.
An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment.
An unmethylated 3' promoter-proximal region is required for efficient transcription initiation.
An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice.
Analysis of a brain-specific isozyme. Expression and chromatin structure of the rat aldolase C gene and transgenes.
Analysis of DNase I hypersensitive site of the ELP gene.
Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance.
Analysis of transcriptional regulation of the small leucine rich proteoglycans.
Aniridia-associated translocations, DNase hypersensitivity, sequence comparison and transgenic analysis redefine the functional domain of PAX6.
AP endonuclease knockdown enhances methyl methanesulfonate hypersensitivity of DNA polymerase ? knockout mouse embryonic fibroblasts.
Assessment of preferential cleavage of an actively transcribed retroviral hybrid gene in murine cells by deoxyribonuclease I, bleomycin, neocarzinostatin, or ionizing radiation.
At least three promoters direct expression of the mouse glucocorticoid receptor gene.
ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor.
Autonomous, erythroid-specific DNase I hypersensitive site formed by human beta-globin locus control region (LCR) 5' HS 2 in transgenic mice.
Autoregulatory loop in the regulation of the mammalian ftz-f1 gene.
Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain.
Base-resolution methylation patterns accurately predict transcription factor bindings in vivo.
Binding of the human papillomavirus E1 origin-recognition protein is regulated through complex formation with the E2 enhancer-binding protein.
Binding of the wheat basic leucine zipper protein EmBP-1 to nucleosomal binding sites is modulated by nucleosome positioning.
BinDNase: a discriminatory approach for transcription factor binding prediction using DNase I hypersensitivity data.
Biochemical and functional analyses of chromatin changes at the TCR-beta gene locus during CD4-CD8- to CD4+CD8+ thymocyte differentiation.
Bisulfighter: accurate detection of methylated cytosines and differentially methylated regions.
Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding.
Brg1-dependent epigenetic control of vascular smooth muscle cell proliferation by hydrogen sulfide.
Bubble-seq analysis of the human genome reveals distinct chromatin-mediated mechanisms for regulating early- and late-firing origins.
C3D: a tool to predict 3D genomic interactions between cis-regulatory elements.
Calcium-dependent activation of interleukin-21 gene expression in T cells.
Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data.
Cas9-mediated excision of proximal DNaseI/H3K4me3 signatures confers robust silencing of microRNA and long non-coding RNA genes.
Causes and consequences of chromatin variation between inbred mice.
Cell lineage specificity of chromatin configuration around the immunoglobulin heavy chain enhancer.
Cell specific differences in DNase I hypersensitivity between the two promoters of the rat glucokinase gene.
Cell-mediated immunity in professional and voluntary blood donors.
Cell-specific expression of the murine CD21 gene depends on accessibility of promoter and intronic elements.
Cell-specific regulation of transcription of the malic enzyme gene: characterization of cis-acting elements that modulate nuclear T3 receptor activity.
Cell-specific transcription of leukotriene C(4) synthase involves a Kruppel-like transcription factor and Sp1.
Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo.
Challenges and opportunities for next-generation sequencing in companion diagnostics.
Changes of DNA methylation and chromatin structure in the human myeloperoxidase gene during myeloid differentiation.
Characterisation of inducible DNase I hypersensitive sites flanking the human interleukin-5 gene.
Characterization of an upstream enhancer region in the promoter of the human endothelial nitric-oxide synthase gene.
Characterization of hepatic-specific regulatory elements in the promoter region of the human cholesterol 7alpha-hydroxylase gene.
Characterization of the human lipoprotein lipase (LPL) promoter: evidence of two cis-regulatory regions, LP-alpha and LP-beta, of importance for the differentiation-linked induction of the LPL gene during adipogenesis.
Characterization of the interaction between Fur and the iron transport promoter of the virulence plasmid in Vibrio anguillarum.
Characterization of the proximal promoter and two silencer elements in the CYP2C11 gene expressed in rat liver.
Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation.
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.
Chromatin alterations surrounding the BCR/ABL fusion gene in K562 cells.
Chromatin configuration of the human CD2 gene locus during T-cell development.
Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis.
Chromatin modifications as clues to the regulation of antigen receptor assembly.
Chromatin structure and DNase I hypersensitivity in the transcriptionally active and inactive porcine tumor necrosis factor gene locus.
Chromatin structure and gene regulation: a dynamic view of enhancer function.
Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma.
Chromatin structure around the c-myc gene in Burkitt lymphomas with upstream and downstream translocation points.
Chromatin structure at the 44D larval cuticle gene locus in Drosophila: the effect of a transposable element insertion.
Chromatin structure of the HLA-DR alpha gene in different functional states of major histocompatibility complex class II gene expression.
Chromatin structure of the regulatory regions of pS2 and cathepsin D genes in hormone-dependent and -independent breast cancer cell lines.
Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells.
Chromosome partitioning in Escherichia coli: novel mutants producing anucleate cells.
Cis-acting sequences which regulate expression of the Sgs-4 glue protein gene of Drosophila.
Cis-active elements controlling lung cell-specific expression of human pulmonary surfactant protein B gene.
Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse.
Combinatorial control of DNase I-hypersensitive site formation and erasure by immunoglobulin heavy chain enhancer-binding proteins.
Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types.
Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.
Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region.
Comparison of amplified and unamplified c-myc gene structure and expression in human small cell lung carcinoma cell lines.
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster.
Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers.
Conserved elements containing NF-E2 and tandem GATA binding sites are required for erythroid-specific chromatin structure reorganization within the human beta-globin locus control region.
Constitutive DNase I hypersensitivity of p53-regulated promoters.
Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene.
Control of gene expression in Xenopus early development.
Coordinate transcription and V(D)J recombination of the kappa immunoglobulin light-chain locus: NF-kappaB-dependent and -independent pathways of activation.
Copper deficiency induces hepatic fatty acid synthase gene transcription in rats by increasing the nuclear content of mature sterol regulatory element binding protein 1.
Correction for Deng et al., "HMGN1 Modulates Nucleosome Occupancy and DNase I Hypersensitivity at the CpG Island Promoters of Embryonic Stem Cells".
Correlations of repetitive and AT-rich DNA segments within the chicken globin gene domains.
Cutting edge: the differential involvement of the N-finger of GATA-3 in chromatin remodeling and transactivation during Th2 development.
De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia.
Deconvolving sequence features that discriminate between overlapping regulatory annotations.
Delayed hypersensitivity. I. Induction of hypersensitivity to diphtheria toxin in guinea pigs by infection with Corynebacterium diphtheriae.
Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity.
Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions.
Dependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimer.
Detecting differentially methylated regions using a fast wavelet-based approach to functional association analysis.
Detection of active transcription factor binding sites with the combination of DNase hypersensitivity and histone modifications.
Determinants of nucleosome positioning and their influence on plant gene expression.
Differences in deoxyribonuclease I hypersensitive sites in phenobarbital-inducible and constitutive rabbit P450IIC genes.
Differences of globin transgene expression in stably transfected cell lines and transgenic mice.
Differential acetylation of histone H3 at the regulatory region of OsDREB1b promoter facilitates chromatin remodelling and transcription activation during cold stress.
Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes.
Differential DNase I hypersensitivity of ras oncogenes in B6C3F1, C3H/He, and C57BL/6 mouse liver.
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.
Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation.
Differential hypersensitivity to DNase I in the regulatory region of human hsp90 beta gene in heat shock and constitutive expression.
Differential regulation of the IL-10 gene in Th1 and Th2 T cells.
Differentiation-dependent chromatin rearrangement coincides with activation of human papillomavirus type 31 late gene expression.
Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
Discriminative prediction of mammalian enhancers from DNA sequence.
Displacement of sequence-specific transcription factors from mitotic chromatin.
Dissecting a locus control region: facilitation of enhancer function by extended enhancer-flanking sequences.
Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations.
Distal regulatory elements required for rat whey acidic protein gene expression in transgenic mice.
Distant HNF1 site as a master control for the human class I alcohol dehydrogenase gene expression.
Distant sequences which regulate globin genes.
DNA distortion and multimerization: novel functions of the glutamine-rich domain of GAGA factor.
DNA methylation affects the formation of active chromatin.
DNA-binding factors shape the mouse methylome at distal regulatory regions.
DNAase I sensitivity and methylation of active versus inactive rRNA genes in xenopus species hybrids.
DNAaseI-hypersensitive minichromosomes of SV40 possess an elastic torsional strain in DNA.
DNase hypersensitivity and methylation of the human CD3G and D genes during T-cell development.
DNase I Digestion of Isolated Nulcei for Genome-Wide Mapping of DNase Hypersensitivity Sites in Chromatin.
DNase I hypersensitive sites and transcriptional activation of the lamin A/C gene.
DNase I hypersensitive sites in Drosophila chromatin occur at the 5' ends of regions of transcription.
DNase I hypersensitive sites in promoter elements associated with basal and vitamin D dependent transcription of the bone-specific osteocalcin gene.
DNase I hypersensitive sites in the 5' flanking region of the human plasminogen activator inhibitor type 2 (PAI-2) gene are associated with basal and tumor necrosis factor-alpha-induced transcription in monocytes.
DNase I hypersensitive sites in the 5'-region of the maize Shrunken gene in nuclei from different organs.
DNase I hypersensitivity analysis of non-pituitary human prolactin gene expression.
DNase I hypersensitivity analysis of the human CCAAT enhancer binding protein epsilon (C/EBPepsilon) gene.
DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements.
DNase I hypersensitivity and epsilon-globin transcriptional enhancement are separable in locus control region (LCR) HS1 mutant human beta-globin YAC transgenic mice.
DNase I hypersensitivity and expression of the Shrunken-1 gene of maize.
DNase I hypersensitivity and methylation of the 5'-flanking region of the alpha 1-fetoprotein gene during developmental and glucocorticoid-induced repression of its activity in rat liver.
DNase I hypersensitivity in the gamma globin gene locus of K562 cells.
DNase I hypersensitivity is independent of endogenous topoisomerase II activity during chicken erythrocyte differentiation.
DNase I hypersensitivity mapping and promoter polymorphism analysis of human C4.
DNase I hypersensitivity of the terminal inverted repeat DNA sequences in the macronucleus of the ciliate Stylonychia mytilus.
DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial cells.
DNase I hypersensitivity sites and nuclear protein binding on the fatty acid synthase gene: identification of an element with properties similar to known glucose-responsive elements.
DNase I sensitivity of integrated simian virus 40 DNA.
DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements.
DNase I-hypersensitive sites associated with expression and hormonal regulation of mouse C4 and Slp genes.
DNase I-hypersensitive sites in the chromatin of immunoglobulin kappa light chain genes.
DNase-I hypersensitivity analysis of the L-type pyruvate kinase gene in rats and transgenic mice.
DNaseI hypersensitivity analysis of chromatin structure.
DNaseI hypersensitivity and ultraconservation reveal novel, interdependent long-range enhancers at the complex Pax6 cis-regulatory region.
DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2.
Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion.
DT40 knock-out and knock-in studies determine the regions necessary and sufficient for transcription and epigenetic conversion of the chicken Ig-? gene.
Dynamic enhancer function in the chromatin context.
Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.
Early de novo DNA methylation and prolonged demethylation in the muscle lineage.
Effect of estrogen receptor ? binding on functional DNA methylation in breast cancer.
Effect of lactoferrin on the phagocytic activity of polymorphonuclear leucocytes isolated from blood of patients with autoimmune diseases and Staphylococcus aureus allergy.
Effect of X-ray induced DNA damage on DNAase I hypersensitivity of SV40 chromatin: relation to elastic torsional strain in DNA.
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.
Enhanced transcription of c-myc in bursal lymphoma cells requires continuous protein synthesis.
Enhancer Associated Long Non-coding RNA Transcription and Gene Regulation in Experimental Models of Rickettsial Infection.
Enhancer complexes located downstream of both human immunoglobulin Calpha genes.
Enhancer sequences responsible for DNase I hypersensitivity in polyomavirus chromatin.
ENHO, RXRA, and LXRA polymorphisms and dyslipidaemia, related comorbidities and survival in haemodialysis patients.
Enkephalin gene transcription in bovine chromaffin cells is regulated by calcium and protein kinase A signal transduction pathways: identification of DNase I-hypersensitive sites.
Eosinophilic Granuloma with Splendore-Hoeppli Material Caused by Toxigenic Corynebacterium ulcerans in a Heifer.
Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region.
Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3' Regulatory Region.
Epigenomic mapping and effect sizes of noncoding variants associated with psychotropic drug response.
Escape from X inactivation varies in mouse tissues.
Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models.
Estimating the effects of transcription factors binding and histone modifications on gene expression levels in human cells.
Estrogen modulates plasminogen promoter activity.
Evaluating the impact of single nucleotide variants on transcription factor binding.
Evidence for a complex regulatory array in the first intron of the human adenosine deaminase gene.
Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter.
Evidence for an intronic cis-regulatory element within CD69 gene.
Evidence that enhanced nasal reactivity to bradykinin in patients with symptomatic allergy is mediated by neural reflexes.
Exhaustive search for epistatic effects on the human methylome.
Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin.
Expression of the secretory leukoprotease inhibitor gene in epithelial cells.
Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types.
Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae.
Fast-muscle-specific expression of human aldolase A transgenes.
Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function.
Fibroblast-like transformation and c-myc gene alteration of human hepatocytes induced by novobiocin and butyrate.
Finding potential cis-regulatory loci using allele-specific chromatin accessibility as weights in a kernel-based variance component test.
Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.
Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription.
Formaldehyde-Assisted Isolation of Regulatory Elements.
FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer.
Friends-Enemies: Endogenous Retroviruses Are Major Transcriptional Regulators of Human DNA.
Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity.
Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus.
Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: the cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo.
Functional selectivity of recombinant mammalian SWI/SNF subunits.
Gap junction Cx26 gene modulation by phorbol esters in benign and malignant human mammary cells.
GATA-3 is an important transcription factor for regulating human NKG2A gene expression.
Gene expression in large pedigrees: analytic approaches.
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Genome-scale mapping of DNase I hypersensitivity.
Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation.
Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases.
Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries.
Genome-Wide Mapping of DNase I Hypersensitive Sites in Tomato.
Genome-wide maps of transcription regulatory elements.
Genome-wide nucleosome positioning is orchestrated by genomic regions associated with DNase I hypersensitivity in rice.
Genome-Wide Prediction and Validation of Intergenic Enhancers in Arabidopsis Using Open Chromatin Signatures.
Genome-wide prediction of DNase I hypersensitivity using gene expression.
Genome-wide prediction of topoisomerase II? binding by architectural factors and chromatin accessibility.
Genome-wide predictors of NF-?B recruitment and transcriptional activity.
Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling.
Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells.
H-NS antagonism in Shigella flexneri by VirB, a virulence gene transcription regulator that is closely related to plasmid partition factors.
Heme Oxygenase-1 Gene Enhancer Manifests Silencing Activity in a Chromatin Environment Prior to Oxidative Stress.
Hepatocyte nuclear factor 1 alpha controls renal expression of the Npt1-Npt4 anionic transporter locus.
Hepatocyte-specific interplay of transcription factors at the far-upstream enhancer of the carbamoylphosphate synthetase gene upon glucocorticoid induction.
Herpes simplex virus associated erythema multiforme (HAEM) is mechanistically distinct from drug-induced erythema multiforme: interferon-gamma is expressed in HAEM lesions and tumor necrosis factor-alpha in drug-induced erythema multiforme lesions.
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells.
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.
High-throughput functional testing of ENCODE segmentation predictions.
Histone acetylation and activation of cAMP-response element-binding protein regulate transcriptional activation of MKP-M in lipopolysaccharide-stimulated macrophages.
Histone acetylation and chromatin remodeling are required for UV-B-dependent transcriptional activation of regulated genes in maize.
HMGN1 modulates nucleosome occupancy and DNase I hypersensitivity at the CpG island promoters of embryonic stem cells.
Hormonal influences on beta-lactoglobulin transgene expression inferred from chromatin structure.
Human apolipoprotein B gene intestinal control region.
Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1-binding sites.
Human immunoglobulin kappa gene enhancer: chromatin structure analysis at high resolution.
Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions.
Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors.
Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen.
Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine.
Identification and characterization of a chicken alpha-globin enhancer.
Identification and characterization of a DNase hypersensitive region of the human tyrosinase gene.
Identification and characterization of an Alu-containing, T-cell-specific enhancer located in the last intron of the human CD8 alpha gene.
Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1.
Identification and Characterization of Human snoRNA Core Promoters.
Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study.
Identification of 3' alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation.
Identification of a candidate regulatory element within the 5' flanking region of the mouse Igh locus defined by pro-B cell-specific hypersensitivity associated with binding of PU.1, Pax5, and E2A.
Identification of a new cis-regulatory element of the terminal deoxynucleotidyl transferase gene in the 5' region of the murine locus.
Identification of a novel cell type-specific intronic enhancer of macrophage migration inhibitory factor (MIF) and its regulation by mithramycin.
Identification of a novel enhancer sequence in the distal promoter of the rat fatty acid synthase gene.
Identification of a novel long non-coding RNA within RUNX1 intron 5.
Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression.
Identification of cell types, tissues and pathways affected by risk loci in psoriasis.
Identification of long range regulatory elements of mouse alpha-globin gene cluster by quantitative associated chromatin trap (QACT).
Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network.
Identification of regulatory elements flanking human XIST reveals species differences.
Identification of upstream cis-acting regulatory elements controlling lineage-specific expression of the mouse NK cell activation receptor, NKR-P1C.
Identifying and mapping cell-type-specific chromatin programming of gene expression.
Identifying gene coexpression networks underlying the dynamic regulation of wood-forming tissues in Populus under diverse environmental conditions.
Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites.
iDHS-DASTS: identifying DNase I hypersensitive sites based on LASSO and stacking learning.
IFN-? suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells.
Immune and allergic reactions to diphtheria toxin and toxoid in guinea-pigs.
Immunoregulatory activities of lactoferrin in the delayed type hypersensitivity in mice are mediated by a receptor with affinity to mannose.
Implication of a new function of human tDNAs in chromatin organization.
In vitro and in vivo footprint analysis of the promoter of carcinoembryonic antigen in colon carcinoma cells: effects of interferon gamma treatment.
In vitro expansion of megakaryocytes from peripheral blood hematopoietic progenitors.
In vivo chromatin structure of the murine interleukin-5 gene region: a new intact cell system.
Inactive allele-specific methylation and chromatin structure of the imprinted gene U2af1-rs1 on mouse chromosome 11.
Induction of globin gene expression during erythroid cell differentiation.
Induction of the glucokinase gene by insulin in cultured neonatal rat hepatocytes. Relationship with DNase-I hypersensitive sites and functional analysis of a putative insulin-response element.
Inhibition of an erythroid differentiation switch by the helix-loop-helix protein Id1.
Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters.
Integrating multiple oestrogen receptor alpha ChIP studies: overlap with disease susceptibility regions, DNase I hypersensitivity peaks and gene expression.
Integration host factor activates the Ner-repressed early promoter of transposable Mu-like phage D108.
Integration of 198 ChIP-seq Datasets Reveals Human cis-Regulatory Regions.
Integration site of human papillomavirus type-18 DNA in chromosome band 8q22.1 of C4-I cervical carcinoma: DNase I hypersensitivity and methylation of cellular flanking sequences.
Integrative Genetic and Epigenetic Analysis Uncovers Regulatory Mechanisms of Autoimmune Disease.
Interaction of a novel sex-dependent, growth hormone-regulated liver nuclear factor with CYP2C12 promoter.
Interaction of the atypical prokaryotic transcription activator FlhD2C2 with early promoters of the flagellar gene hierarchy.
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.
Interferon induction of gene transcription analyzed by in vivo footprinting.
Interleukin-6 repression is associated with a distinctive chromatin structure of the gene.
Interleukin-8 gene expression in human bronchial epithelial cells.
Intermediate DNA methylation is a conserved signature of genome regulation.
Introduction of exogenous class II trans-activator in MHC class II-deficient ABI fibroblasts results in incomplete rescue of MHC class II antigen expression.
Involvement of AP-2 in regulation of the R-FABP gene in the developing chick retina.
Isolation and characterization of minichromosome particles that contain a glucocorticoid-modulated promoter.
Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I.
Lactoferrin as an Adjuvant for the Generation of Delayed Type Hypersensitivity to Orally Administered Antigen.
Lactoferrin immunomodulation of DTH response in mice.
Lactoferrin inhibits the effector phase of the delayed type hypersensitivity to sheep erythrocytes and inflammatory reactions to M. bovis (BCG).
Lactoferrin modulation of IL-12 and IL-10 response from activated murine leukocytes.
Lactoferrin, a glycoprotein with immunomodulatory and mast cell stabilising properties, in skin of horses suffering from Culicoides hypersensitivity.
Lactoferrin, myeloperoxidase, lysozyme and eosinophil cationic protein in exudate in delayed type hypersensitivity.
Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.
Liver-specific and proliferation-induced deoxyribonuclease I hypersensitive sites in the mouse insulin-like growth factor binding protein-1 gene.
Local character of readthrough activation in adenovirus type 5 early region 1 transcription control.
Local compartment changes and regulatory landscape alterations in histone H1-depleted cells.
Localization of DNase I hypersensitive sites in the human oestrogen receptor gene correlates with the transcriptional activity of two differentially used promoters.
Long conserved fragments upstream of Mammalian polyadenylation sites.
Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.
Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte.
Loss of irreversibility of granulocytic differentiation induced by dimethyl sulfoxide in HL-60 sublines with a homogeneously staining region.
Loss of Major DNase I Hypersensitive Sites in Duplicated ?-globin Gene Cluster Incompletely Silences HBB Gene Expression.
Mammalian Comparative Genomics Reveals Genetic and Epigenetic Features Associated with Genome Reshuffling in Rodentia.
Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq.
Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip).
Mechanism of dexamethasone 21-mesylate antiglucocorticoid action: II. Receptor-antiglucocorticoid complexes do not interact productively with mouse mammary tumor virus long terminal repeat chromatin.
Mechanisms of Enhancer-mediated Hormonal Control of Vitamin D Receptor Gene Expression in Target Cells.
Meiosis-induced double-strand break sites determined by yeast chromatin structure.
Meiotic crossovers are associated with open chromatin and enriched with Stowaway transposons in potato.
Methods for Analyzing the Role of DNA Methylation and Chromatin Structure in Regulating T Lymphocyte Gene Expression.
Methods for identification of epigenetic elements in mammalian long multigenic genome sequences.
MGMT Epigenetics: The Influence of Gene Body Methylation and Other Insights Derived from Integrated Methylomic, Transcriptomic, and Chromatin Analyses in Various Cancer Types.
Mitochondrial RNA polymerase of Saccharomyces cerevisiae: composition and mechanism of promoter recognition.
Modeling co-occupancy of transcription factors using chromatin features.
Modeling gene expression using chromatin features in various cellular contexts.
Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure.
Modulation of glucocorticoid induction of stably transfected tyrosine aminotransferase gene constructs involves elements up-stream of the glucocorticoid-responsive element.
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.
Molecular analysis of a recombinational hotspot adjacent to Lmp2 gene in the mouse MHC: fine location and chromatin structure.
Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1.
Molecular and genetic organization of bands and interbands in the dot chromosome of Drosophila melanogaster.
Molecular architecture of the hsp70 promoter after deletion of the TATA box or the upstream regulation region.
Molecular characterization of two extra marker chromosomes detected at prenatal diagnosis.
Molecular events involved in regulating human interferon-gamma gene expression during T cell activation.
MOST+: A de novo motif finding approach combining genomic sequence and heterogeneous genome-wide signatures.
msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.
Multimodal Imaging and Functional Testing in a North Carolina Macular Disease Family: Toxoplasmosis, Fovea Plana, and Torpedo Maculopathy Are Phenocopies.
Multiple control elements are required for expression of the human CD34 gene.
Multiple enhancer regions govern the transcription of CCN2 during embryonic development.
Murine erythroleukemia cell differentiation: DNase I hypersensitivity and DNA methylation near the globin genes.
mus308 mutants of Drosophila exhibit hypersensitivity to DNA cross-linking agents and are defective in a deoxyribonuclease.
Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice.
Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat.
Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin.
Myogenic differential methylation: diverse associations with chromatin structure.
Native genomic blotting: high-resolution mapping of DNase I-hypersensitive sites and protein-DNA interactions.
Negative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element.
NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.
Nonresponsiveness of normal human fibroblasts to dioxin correlates with the presence of a constitutive xenobiotic response element-binding factor.
North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13.
Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus.
Novel DNase I hypersensitive sites in the 3'-flanking region of the human c-myc gene.
Novel regional age-associated DNA methylation changes within human common disease-associated loci.
Nuclear factor binding to a DNA sequence element that represses MMTV transcription induces a structural transition and leads to the contact of single-stranded binding proteins with DNA.
Nuclease hypersensitivity of the rat cytochrome P450IA1 gene.
Nucleosome organisation of the beta-lactoglobulin gene. Transcription complex formation.
Nucleosomes are translationally positioned on the active allele and rotationally positioned on the inactive allele of the HPRT promoter.
Nutritional regulation and tissue-specific expression of the malic enzyme gene in the chicken. Transcriptional control and chromatin structure.
Nutritional regulation and tissue-specific expression of the serine dehydratase gene in rat.
Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci.
Only the promoter region of the constitutively expressed normal and amplified human dihydrofolate reductase gene is DNase I hypersensitive and undermethylated.
Organization, sequence and nuclease hypersensitivity of repetitive elements flanking the chicken apoVLDLII gene: extended sequence similarity to elements flanking the chicken vitellogenin gene.
Overexpression of c-Myc inhibits the appearance of a specific DNase I hypersensitive site in the beta-globin chromatin in murine erythroleukemia cells.
p53 binds to a constitutively nucleosome free region of the mdm2 gene.
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
PeaKDEck: a kernel density estimator-based peak calling program for DNaseI-seq data.
Permeabilized Arabidopsis protoplasts provide new insight into the chromatin structure of plant alcohol dehydrogenase genes.
Perturbation of chromatin architecture on ecdysterone induction of Drosophila melanogaster small heat shock protein genes.
Phosphorylation-mediated control of chromatin organization and transcriptional activity of the tissue-specific osteocalcin gene.
Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming.
Platelet-activating factor- and leukotriene B4-induced release of lactoferrin from blood neutrophils of atopic and nonatopic individuals.
Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans.
Position effects are influenced by the orientation of a transgene with respect to flanking chromatin.
Positive and negative regulation of gene expression by insulin and glucagon: the model of L-type pyruvate kinase gene.
Positive and negative regulatory elements of chicken vitellogenin II gene characterized by in vitro transcription competition assays in a homologous system.
Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development.
Predicting transcription factor site occupancy using DNA sequence intrinsic and cell-type specific chromatin features.
Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach.
Prenatal immune activation alters the adult neural epigenome but can be partly stabilised by a n-3 polyunsaturated fatty acid diet.
Presetting of chromatin structure and transcription factor binding poise the human GADD45 gene for rapid transcriptional up-regulation.
Probing DNA shape and methylation state on a genomic scale with DNase I.
Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing.
Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.
Prospective estimation of IgG, IgG subclass and IgE antibodies to dietary proteins in infants with cow milk allergy. Levels of antibodies to whole milk protein, BLG and ovalbumin in relation to repeated milk challenge and clinical course of cow milk allergy.
PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA.
Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy.
Putative intestine-specific enhancers located in 5' sequence of the CDX1 gene regulate CDX1 expression in the intestine.
Quantitative analysis of genome-wide chromatin remodeling.
Quantitative characterization of tumor cell-free DNA shortening.
Rapid high-throughput analysis of DNaseI hypersensitive sites using a modified Multiplex Ligation-dependent Probe Amplification approach.
Recurrent patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines.
Reevaluation of SNP heritability in complex human traits.
Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification.
Regulated expression of p18, a major phosphoprotein of leukemic cells.
Regulation of anaerobic arginine catabolism in Bacillus licheniformis by a protein of the Crp/Fnr family.
Regulation of expression of the human interferon gamma gene.
Regulation of gene expression in mast cells: micro-rNA expression and chromatin structural analysis of cytokine genes.
Regulation of globin gene expression during induced erythroid cell differentiation.
Regulation of the Cobalt/Nickel Efflux Operon dmeRF in Agrobacterium tumefaciens and a Link between the Iron-Sensing Regulator RirA and Cobalt/Nickel Resistance.
Regulation of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7A): prevalence of negative over positive transcriptional control.
Regulation of the interleukin-7 receptor alpha promoter by the Ets transcription factors PU.1 and GA-binding protein in developing B cells.
Regulation of the laminin beta 1 (LAMB1), retinoic acid receptor beta, and bone morphogenetic protein 2 genes in mutant F9 teratocarcinoma cell lines partially deficient in cyclic AMP-dependent protein kinase activity.
Regulation of type I collagen gene expression in human skin fibroblast cultures: DNA methylation and DNase I hypersensitivity.
Regulation of tyrosine aminotransferase gene expression by glucocorticoids in quiescent and regenerating liver.
Regulatory elements and genetic variations in periodontal diseases.
Regulatory genomic regions active in immune cell types explain a large proportion of the genetic risk of multiple sclerosis.
Release of lactoferrin and elastase in human allergic skin reactions.
Remodeling the chromatin structure of a nucleosome array by transcription factor-targeted trans-displacement of histones.
Remodelling of the S3 PA700 proteasome activator gene chromatin structure during thymocyte differentiation.
Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.
Repression of CD2 gene expression is mediated by an AP-2 related factor.
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer.
Requirement of distal and proximal promoter sequences for chromatin organization of the osteocalcin gene in bone-derived cells.
Retinoid receptor-induced alteration of the chromatin assembled on a ligand-responsive promoter in Xenopus oocytes.
Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoter.
RNA chain initiation by Escherichia coli RNA polymerase. Structural transitions of the enzyme in early ternary complexes.
Rodent-specific hypoxia response elements enhance PAI-1 expression through HIF-1 or HIF-2 in mouse hepatoma cells.
Role of a distal enhancer in the transcriptional responsiveness of the human CD200 gene to interferon-gamma and tumor necrosis factor-alpha.
Role of chromatin structure in transcriptional regulation of MMTV LTR hormone-dependent promoter.
Role of the promoter in maintaining transcriptionally active chromatin structure and DNA methylation patterns in vivo.
Safety of repeated intermittent courses of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis.
SEdb: a comprehensive human super-enhancer database.
Selective loss of a DNase I hypersensitive site upstream of the tyrosine aminotransferase gene in mice homozygous for lethal albino deletions.
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
Sequence-specific targeting of Drosophila roX genes by the MSL dosage compensation complex.
Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice.
Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.
Several Critical Cell Types, Tissues, and Pathways Are Implicated in Genome-Wide Association Studies for Systemic Lupus Erythematosus.
Silencing of Fshr occurs through a conserved, hypersensitive site in the first intron.
Simian virus 40 early- and late-region promoter functions are enhanced by the 72-base-pair repeat inserted at distant locations and inverted orientations.
Simian virus 40-mediated cis induction of the Xenopus beta-globin DNase I hypersensitive site.
Single mutations at many sites within the DNA polymerase locus of herpes simplex viruses can confer hypersensitivity to aphidicolin and resistance to phosphonoacetic acid.
Site-specific silencing of regulatory elements as a mechanism of X inactivation.
Sites hypersensitive to, and protected from, nuclease digestion in the regulatory region of wild-type and mutant polyoma chromatin.
SMAR1 and Cux/CDP modulate chromatin and act as negative regulators of the TCRbeta enhancer (Ebeta).
SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes.
Sodium butyrate inhibits cell growth and stimulates p21WAF1/CIP1 protein in human colonic adenocarcinoma cells independently of p53 status.
Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma.
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells.
Sperm decondensation during fertilisation in the mouse: presence of DNase I hypersensitive sites in situ and a putative role for topoisomerase II.
Spironolactone, an aldosterone antagonist, acts as an antiglucocorticosteroid on the mouse mammary tumor virus promoter.
Ssn6-Tup1 regulates RNR3 by positioning nucleosomes and affecting the chromatin structure at the upstream repression sequence.
Stability of a Lac repressor mediated "looped complex".
STAG-CNS: An Order-Aware Conserved Noncoding Sequences Discovery Tool for Arbitrary Numbers of Species.
STAT3, STAT4, NFATc1, and CTCF Regulate PD-1 through Multiple Novel Regulatory Regions in Murine T Cells.
Structural alteration from non-B to B-form could reflect DNase I hypersensitivity.
Structural analysis and mapping of DNase I hypersensitivity of HS5 of the beta-globin locus control region.
Structural analysis of the proximal region of the microtubule-associated protein 1B promoter.
Structural characterization of the human DNA topoisomerase I gene promoter.
Structure of the chicken interferon-gamma gene, and comparison to mammalian homologues.
Structure, DNaseI hypersensitivity and expression of integrated papilloma virus in the genome of HeLa cells.
Studies of the constitutive expression of the mouse erythropoietin gene.
Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta7 (CD103).
Supercoil-dependent features of DNA structure at Drosophila locus 67B1.
Suppression of the delayed cutaneous hypersensitivity response in hepatoma patients: test by antigen of streptokinase and streptodornase.
SV40-alpha-globulin hybrid minichromosomes. Differences in DNase I hypersensitivity of promoter and enhancer sequences.
Systematic enrichment analysis of potentially functional regions for 103 prostate cancer risk-associated loci.
Systemic or local co-administration of lactoferrin with sensitizing dose of antigen enhances delayed type hypersensitivity in mice.
T cell-specific expression of the human TNF-alpha gene involves a functional and highly conserved chromatin signature in intron 3.
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription.
Targeted remodeling of human beta-globin promoter chromatin structure produces increased expression and decreased silencing.
Tear Lactoferrin and Features of Ocular Allergy in Different Severities of Meibomian Gland Dysfunction.
Temporal establishment of neural cell identity in vivo and in vitro.
TFmapper: A Tool for Searching Putative Factors Regulating Gene Expression Using ChIP-seq Data.
The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4.
The 5' flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice.
The beta7 integrin gene (Itgb-7) promoter is responsive to TGF-beta1: defining control regions.
The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter.
The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors.
The distribution and causes of meiotic recombination in the human genome.
The distribution of genes on chromosomes: a cytological approach.
The distribution of genes on human chromosomes as studied by in situ nick translation.
The DNA binding domain of the varicella-zoster virus gene 62 protein interacts with multiple sequences which are similar to the binding site of the related protein of herpes simplex virus type 1.
The Drosophila broad-complex regulates developmental changes in transcription and chromatin structure of the 67B heat-shock gene cluster.
The effect of thyroid hormone on the chromatin structure and expression of the malic enzyme gene in hepatocytes.
The ENCODE Project at UC Santa Cruz.
The expression of integrated plasmid DNA depends on copy number.
The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure.
The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure.
The Higher Structure of Chromatin in the LCR of the beta-Globin Locus Changes during Development.
The human desmin locus: gene organization and LCR-mediated transcriptional control.
The human IL-13 locus in neonatal CD4+ T cells is refractory to the acquisition of a repressive chromatin architecture.
The immunoglobulin mu enhancer core establishes local factor access in nuclear chromatin independent of transcriptional stimulation.
The LTR promoter of the rat oncomodulin gene is regulated by cell-line specific accessibility in the LTR U3 region.
The majority of primate-specific regulatory sequences are derived from transposable elements.
The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.
The mitochondrial uncoupling protein gene in brown fat: correlation between DNase I hypersensitivity and expression in transgenic mice.
The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding.
The mouse albumin promoter and a distal upstream site are simultaneously DNase I hypersensitive in liver chromatin and bind similar liver-abundant factors in vitro.
The nuclear matrix protein CDP represses hepatic transcription of the human cholesterol-7alpha hydroxylase gene.
The regulatory domain of a larval serum protein gene in Drosophila melanogaster.
The role of transcriptional activator GATA-1 at human beta-globin HS2.
The smooth muscle myosin heavy chain gene exhibits smooth muscle subtype-selective modular regulation in vivo.
The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.
The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells.
The tripartite DNA element responsible for diet-induced rat fatty acid synthase (FAS) regulation.
The use of DNase I hypersensitivity site mapping to identify regulatory regions of the human cholinergic gene locus.
Time-resolved footprinting for the study of the structural dynamics of DNA-protein interactions.
Tissue specific expression of avian vitellogenin gene is correlated with DNA hypomethylation and in vivo specific protein-DNA interactions.
Tissue-restricted expression of the Cdrap/Mia gene within a conserved multigenic housekeeping locus.
Tissue-specific chromatin structure of the phenobarbital-responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital.
Tissue-specific DNase I hypersensitive sites in a foreign globin gene in transgenic mice.
Tissue-specific DNaseI hypersensitive sites in the 5'-flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes.
Tissue-specific DNaseI hypersensitivity regions are located in the 5'-region of the rat preproenkephalin gene.
Tissue-specific expression of murine keratin K13 in internal stratified squamous epithelia and its aberrant expression during two-stage mouse skin carcinogenesis is associated with the methylation state of a distinct CpG site in the remote 5'-flanking region of the gene.
Tissue-specific patterns of allelically-skewed DNA methylation.
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders.
Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus.
Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.
Transcription of the rat serine protease inhibitor 2.1 gene in vivo: correlation with GAGA box promoter occupancy and mechanism of cytokine-mediated down-regulation.
Transcriptional activation of the chlorocatechol degradative genes of Ralstonia eutropha NH9.
Transcriptional control of transglutaminase 2 expression in mouse apoptotic thymocytes.
Transcriptional regulation and chromatin structure of the human CD34 gene promoter region.
Transcriptional regulation of the FSH receptor: new perspectives.
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen.
Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter.
Transient T-bet expression functionally specifies a distinct T follicular helper subset.
Triiodothyronine stimulates and cyclic AMP inhibits transcription of the gene for malic enzyme in chick embryo hepatocytes in culture.
Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2.
Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta.
Undermethylation and DNase I hypersensitivity of myeloperoxidase gene in HL-60 cells before and after differentiation.
Upstream NFIL-6-like site located within a DNase I hypersensitivity region mediates LPS-induced transcription of the murine interleukin-1 beta gene.
Use of a recombination reporter insert to define meiotic recombination domains on chromosome III of Saccharomyces cerevisiae.
Using ROADMAP Data to Identify Enhancers Associated with Disorders of Sex Development.
Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences.
Widespread Exonization of Transposable Elements in Human Coding Sequences is Associated with Epigenetic Regulation of Transcription.
Zika Virus Congenital Syndrome and MTOR gene variants: insights from a family of dizygotic twins.
[Analysis of cell specific transcription of the human cone transducin alpha subunit gene]
[DNAase I hypersensitivity of the 1,5'-flanking region of the tryptophan oxygenase gene in recombinant DNA and chromatin reconstituted with it]
[Effect of lactoferrin on the phagocytic activity of neutrophils isolated from the blood of patients with collagenoses and Staphylococcus aureus allergy]
[Effect of X-ray-induced DNA breaks on the hypersensitivity of the minichromosomes of SV40 virus to DNAse I]
[Hypersensitivity to DNAse I of flexible DNA in the composition of transcriptionally active SV40 virus minichromosomes]
[Infectious allergy. 3. The effect of desensitizing drugs on the course and outcome of infectious allergy caused by diphtheria toxin]
[Maintenance of torsional tension in DNA of transactivated genes during the cell cycle]
[Specific interaction of a nuclear protein factor from the CTF/NF-I family with 2 different promoter regions of the rat tyrosine aminotransferase gene]
[Structural features of chromatin organization of 3C6/C7 interband in Drosophila melanogaster polytene chromosomes].
[Systems biology and the project "Encode"].
[Transcriptional activation study of transforming gene Tx-related human nasopharyngeal carcinoma]
[Various novel properties of transcriptionally active mini-chromosomes of the SV40 virus]
Hypersensitivity, Delayed
Delayed hypersensitivity. I. Induction of hypersensitivity to diphtheria toxin in guinea pigs by infection with Corynebacterium diphtheriae.
Transfer of delayed hypersensitivity to diphtheria toxin in man.
Use of diphtheria toxin and toxoid in the study of immediate and delayed hypersensitivity in man.
Hypertension
Antioxidant effects of bovine lactoferrin on dexamethasone-induced hypertension in rat.
DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features.
Human monocyte transcriptional profiling identifies IL-18 receptor accessory protein and lactoferrin as novel immune targets in hypertension.
In vivo angiotensin I-converting enzyme inhibition by long-term intake of antihypertensive lactoferrin hydrolysate in spontaneously hypertensive rats
[An association of selected polymorphisms of the lactoferrin gene and genes for lactoferrin receptors in the prevalence of metabolic disorders in obese subjects].
Hyperthyroidism
Rapid induction of rat liver S14 gene transcription by thyroid hormone.
[Participation of thyroid hormones in realization of the action of diphtheria toxin on oxidative phosphorylation in rabbit liver mitochondria]
Hypoalbuminemia
Dane particle DNA polymerase and HBeAg: impact on clinical, laboratory, and histologic findings in hepatitis B-associated chronic liver disease.
Hypogonadism
Defective DNA Polymerase ?-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism.
Hypophosphatemia
Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling.
Hypopituitarism
Body growth and lymphocyte DNA polymerase activity in patients with hypopituitarism.
Hypotension
Lactoferrin moderates LPS-induced hypotensive response and gut injury in rats.
Hypothyroidism
Effect of hypothyroidism on different forms of actin in rat cerebral neuronal cultures studied by an improved DNase I inhibition assay.
Mitochondrial DNA, RNA and protein synthesis in normal and hypothyroid developing rat liver.
[Participation of thyroid hormones in realization of the action of diphtheria toxin on oxidative phosphorylation in rabbit liver mitochondria]
Ichthyosis
Diverse roles of RAD18 and Y-family DNA polymerases in tumorigenesis.
Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H.
Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri.
Ileus
[A clinical application of the fibrinolytic streptococcic activator; post-operative ileus caused by massive tubercular fibroadhesive peritonitis; re-operation; intraperitoneal administration of streptodornase and streptokinase; recovery.]
Immune System Diseases
DNase1: No Association with Crohn's Disease in a New Zealand Population.
Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS.
[The superoxide theory of pathogenesis and therapy of immune disorders]
Infarction, Middle Cerebral Artery
Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death.
Infections
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections.
A case of cutaneous toxigenic Corynebacterium ulcerans likely acquired from a domestic dog.
A comparison of streptokinase and streptodornase with urea in the treatment of surgical infections.
A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase ? is dispensable for HIV-1 infection in dividing and nondividing cells.
A curcumin-based 1-week triple therapy for eradication of Helicobacter pylori infection: something to learn from failure?
A deoxyribonuclease found after infection of Bacillus subtilis with phage SP3.
A DEOXYRIBONUCLEASE INDUCED BY INFECTION WITH BACTERIOPHAGE T2.
A DNase from a Fungal Phytopathogen Is a Virulence Factor Likely Deployed as Counter Defense against Host-Secreted Extracellular DNA.
A hybrid toxin from bacteriophage f1 attachment protein and colicin E3 has altered cell receptor specificity.
A milk protein lactoferrin enhances human T cell leukemia virus type I and suppresses HIV-1 infection.
A Multi-Technique Reconfigurable Electrochemical Biosensor: Enabling Personal Health Monitoring in Mobile Devices.
A Mutation in the gene-encoding bacteriophage T7 DNA polymerase that renders the phage temperature-sensitive.
A non-invasive quantitative assay to measure murine intestinal inflammation using the neutrophil marker lactoferrin.
A novel antimicrobial peptide derived from modified N-terminal domain of bovine lactoferrin: design, synthesis, activity against multidrug-resistant bacteria and Candida.
A novel experimental platform for toxigenic and non-toxigenic Corynebacterium ulcerans infection in mice.
A novel primase-free form of murine DNA polymerase alpha induced by infection with minute virus of mice.
A novel recombinant human lactoferrin augments the BCG vaccine and protects alveolar integrity upon infection with Mycobacterium tuberculosis in mice.
A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to Mexico.
A protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro.
A randomized controlled trial of consensus interferon with or without lactoferrin for chronic hepatitis C patients with genotype 1b and high viral load.
A reliable internally controlled RT-nested PCR method for the detection of hepatitis C virus RNA.
A small RNA promotes siderophore production through transcriptional and metabolic remodeling.
A transcriptionally active form of TFIIIC is modified in poliovirus-infected HeLa cells.
Abortive infection by bacteriophage BF23 due to the colicin Ib factor. I. Genetic studies of nonrestricted and amber mutants of bacteriophage BF23.
Abortive infection by bacteriophage BF23 due to the colicin Ib factor. II. Involvement of pre-early proteins.
AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening.
Activity of hypothiocyanite and lactoferrin (ALX-009) against respiratory cystic fibrosis pathogens in sputum.
Acute cytomegalovirus infection complicated by venous thrombosis in a renal transplant recipient.
Acyclic nucleosides as antiviral compounds.
Acyclovir or Abeta42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells.
Adenovirus mediated transduction of the human DNA polymerase eta cDNA.
Adenovirus Serotype 5 Infects Human Dendritic Cells via a CAR-Independent Receptor Pathway Mediated by Lactoferrin and DC-SIGN.
Adenovirus-induced inhibition of cellular DNase.
Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells.
Advances in lactoferrin research concerning bovine mastitis.
Advances in the treatment of varicella-zoster virus infections.
Aerosolized Bovine Lactoferrin Counteracts Infection, Inflammation and Iron Dysbalance in A Cystic Fibrosis Mouse Model of Pseudomonas aeruginosa Chronic Lung Infection.
Aerosolized bovine lactoferrin reduces neutrophils and pro-inflammatory cytokines in mouse models of Pseudomonas aeruginosa lung infections.
Aerosolized pancreatic dornase and antibiotics in pulmonary infections: use in patients with postoperative and nonoperative infections.
Age-prevalence of Otarine Herpesvirus-1, a tumor-associated virus, and possibility of its sexual transmission in California sea lions.
Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance.
Altered degradation of epidermal growth factor in a diphtheria toxin-resistant clone of KB cells.
Altered expression of adenovirus 12 DNA-binding protein but not DNA polymerase during abortive infection of hamster cells.
Alveolar Echinococcosis Mimicking a Hepatic Neoplasm with Lymph Node Metastasis: A Case Report.
Amino acid residues critical for the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin.
Amniotic fluid lactoferrin in intrauterine infection.
Amniotic-fluid Lactoferrin: A Marker for Subclinical Intraamniotic Infection Prior to 32 Weeks Gestation.
An antimicrobial protein, lactoferrin exists in the sweat: proteomic analysis of sweat.
An antimutator deoxyribonucleic acid polymerase. II. In vitro and in vivo studies of its temperature sensitivity.
An overview of letermovir: a cytomegalovirus prophylactic option.
Anaplasma phagocytophilum Asp14 is an invasin that interacts with mammalian host cells via its C terminus to facilitate infection.
Anaplasma phagocytophilum outer membrane protein A interacts with sialylated glycoproteins to promote infection of mammalian host cells.
Anti-Candida activity of calprotectin in combination with neutrophils or lactoferrin.
Anti-HSV activity of lactoferricin analogues is only partly related to their affinity for heparan sulfate.
Anti-Invasive Activity of Bovine Lactoferrin against Listeria monocytogenes.
Anti-lactoferrin toxicity and elevated iron: The environmental prerequisites which activate susceptibility to tuberculosis infection?
Antibacterial activity of lysozyme and lactoferrin is inhibited by binding of advanced glycation-modified proteins to a conserved motif.
Antibacterial and Anti-biofilm Activity of the Human Breast Milk Glycoprotein Lactoferrin against Group B Streptococcus.
Antibacterial and immunomodulatory activities of bovine lactoferrin against Escherichia coli O157:H7 infections in cattle.
Antibacterial and immunomodulatory effects of Pheromonicin-NM on Escherichia coli-challenged bovine mammary epithelial cells.
Antibacterial prophylaxis with lactoferrin in neutropenic patients.
Antibiotic properties of bovine lactoferrin on Helicobacter pylori.
Antibiotic resistance and plasmid profiles of Escherichia coli and Klebsiella isolated from in-patients receiving prolonged antibiotic therapy.
Antibodies to Epstein-Barr virus-specific DNase and DNA polymerase in the chronic fatigue syndrome.
Antifungal Spectrum and Fungicidal Mechanism of an N-Terminal Peptide of Bovine Lactoferrin.
Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and functionalisation with dornase alfa (DNase).
Antimicrobial peptides of the vaginal innate immunity and their role in the fight against sexually transmitted diseases.
Antimicrobial proteins in sterilised human milk.
Antiviral Action of Native and Methylated Lactoferrin and ?-Lactoglobulin against Potato Virus Y (PVY) Infected into Potato Plants Grown in an Open Field.
Antiviral activity of human lactoferrin: inhibition of alphavirus interaction with heparan sulfate.
Antiviral activity of lactoferrin against canine herpesvirus.
Antiviral activity of ovotransferrin discloses an evolutionary strategy for the defensive activities of lactoferrin.
Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection.
Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro.
Antiviral properties of lactoferrin-a natural immunity molecule.
Antiviral treatment of chronic hepatitis B virus infection: infectious virus cannot be detected in patient serum after permanent responses to treatment.
AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections.
APOL1 toxin, innate immunity, and kidney injury.
Association between anti-CD4 antibodies and a decline in CD4+ lymphocytes in human immunodeficiency virus type 1 seroconverters.
Association between practice patterns and body mass index percentile in infants and young children with cystic fibrosis.
Association of hemolysin production, hemagglutination of human erythrocytes, and virulence for chicken embryos of extraintestinal Escherichia coli isolates.
Association of human cytomegalovirus (HCMV) with mink and rabbit lung cells.
Association of iss and iucA, but not tsh, with plasmid-mediated virulence of avian pathogenic Escherichia coli.
Attenuation of biopterin synthesis prevents Escherichia coli K1 invasion of brain endothelial cells and the development of meningitis in newborn mice.
Augmentation of Urinary Lactoferrin Enhances Host Innate Immune Clearance of Uropathogenic Escherichia coli.
Bacillus subtilis deoxyuridinetriphosphatase and its bacteriophage PBS2-induced inhibitor.
Bacterial lactoferrin receptors.
Bacterial phage receptors, versatile tools for display of polypeptides on the cell surface.
Bacteriocin production by Shigella sonnei isolated from faeces of children with acute diarrhoea.
Bacteriophage f1 infection and colicin tolerance.
Bacteriophage SPO1 DNA polymerase and the activity of viral gene 31.
Bacteriophage T5 growth in Escherichia coli containing PstI fragments of the colicin Ib plasmid.
Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits.
Bacteriostatic activity of human lactoferrin against Staphylococcus aureus is a function of its iron-binding properties and is not influenced by antibiotic resistance.
Baculovirus induction of a DNA polymerase.
BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child.
Bioactive Proteins in Human Milk: Health, Nutrition, and Implications for Infant Formulas.
Biological Activities of Uric Acid in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli.
Biosynthesis and disulfide cross-linking of outer membrane components during the growth cycle of Chlamydia trachomatis.
BK virus encoded microRNAs are present in blood of renal transplant recipients with BK viral nephropathy.
Bone infection: its problems and attacks, with special mention of streptokinase and streptodornase.
Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae.
Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replication.
Bovine herpesvirus-1 infection reduces bronchial epithelial cell migration to extracellular matrix proteins.
Bovine Lactoferricin Induces Intestinal Epithelial Cell Activation through Phosphorylation of FAK and Paxillin and Prevents Rotavirus Infection.
Bovine lactoferrin activity against Chikungunya and Zika viruses.
Bovine lactoferrin and lactoferricin interfere with intracellular trafficking of Herpes simplex virus-1.
Bovine lactoferrin binding to six species of coagulase-negative staphylococci isolated from bovine intramammary infections.
Bovine lactoferrin counteracts toll-like receptor mediated activation signals in antigen presenting cells.
Bovine lactoferrin enhances the efficacy of levofloxacin-based triple therapy as first-line treatment of Helicobacter pylori infection: an in vitro and in vivo study.
Bovine Lactoferrin Enhances TLR7-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D.
Bovine lactoferrin inhibits adenovirus infection by interacting with viral structural polypeptides.
Bovine lactoferrin inhibits Japanese encephalitis virus by binding to heparan sulfate and receptor for low density lipoprotein.
Bovine lactoferrin peptidic fragments involved in inhibition of Echovirus 6 in vitro infection.
Bovine lactoferrin peptidic fragments involved in inhibition of herpes simplex virus type 1 infection.
Bovine Lactoferrin Pre-Treatment Induces Intracellular Killing of AIEC LF82 and Reduces Bacteria-Induced DNA Damage in Differentiated Human Enterocytes.
Bovine Lactoferrin to Prevent Neonatal Infections in Low-Birth-Weight Newborns in Pakistan: Protocol for a Three-Arm Double-Blind Randomized Controlled Trial.
Bovine lactoferrin-derived peptides as novel broad-spectrum inhibitors of influenza virus.
Bovine lactoferrin: benefits and mechanism of action against infections.
Breast-feeding, a complex support system for the offspring.
Breastfeeding provides passive and likely long-lasting active immunity.
Bronchopleural communication following intrapleural doses of tPA/DNase for empyema.
C2 from Beet curly top virus promotes a cell environment suitable for efficient replication of geminiviruses, providing a novel mechanism of viral synergism.
Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKC? Activation.
Calprotectin and lactoferrin faecal levels in patients with Clostridium difficile infection (CDI): a prospective cohort study.
Camel lactoferrin markedly inhibits hepatitis C virus genotype 4 infection of human peripheral blood leukocytes.
Can nutraceuticals assist treatment and improve covid-19 symptoms?
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin.
CD209/DC-SIGN mediates efficient infection of monocyte-derived dendritic cells by clinical adenovirus 2C isolates in the presence of bovine lactoferrin.
Cell cycle arrest by human cytomegalovirus 86-kDa IE2 protein resembles premature senescence.
Cell envelope signaling in Escherichia coli. Ligand binding to the ferrichrome-iron receptor fhua promotes interaction with the energy-transducing protein TonB.
Cervico-vaginal mucus (CVM) - an accessible source of immunologically informative biomolecules.
Changes in lactoferrin, immunoglobulin G, bovine serum albumin, and alpha-lactalbumin during acute experimental and natural coliform mastitis in cows.
Changes of immunophysiological characteristics in neonatal calves experimentally challenged with mixture of live bacteria and virus.
Characterization and functional analysis of the porcine lactoferrin gene promoter.
Characterization of a cidofovir-resistant HHV-6 mutant obtained by in vitro selection.
Characterization of a human immunodeficiency virus type 1 pre-integration complex in which the majority of the cDNA is resistant to DNase I digestion.
Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa.
Characterization of antiviral activity of lactoferrin against hepatitis C virus infection in human cultured cells.
Characterization of binding of human lactoferrin to pneumococcal surface protein A.
Characterization of monoclonal antibodies against human lactoferrin.
Characterization of pseudotype VSV possessing HCV envelope proteins.
Characterization of recombinant human lactoferrin secreted in milk of transgenic mice.
Characterization of single nucleotide polymorphism in the 5'-untranslated region (5'-UTR) of Lactoferrin gene and its association with reproductive parameters and uterine infection in dairy cattle.
Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase.
Characterization of Sulfolobus islandicus rod-shaped virus 2 gp19, a single-strand specific endonuclease.
Characterization of the deoxyribonuclease activity induced by infection with herpes virus.
Characterization of the early steps of herpes simplex virus replication in interferon-treated human cells.
Characterization of the Epstein-Barr virion-associated DNA polymerase as isolated from superinfected and drug-stimulated cells.
Characterization of the infection-responsive bovine lactoferrin promoter.
Characterization of the replication of a baculovirus mutant lacking the DNA polymerase gene.
Chlamydia trachomatis OmpA genotyping as a tool for studying the natural history of genital chlamydial infection.
Chromatin structure of simian virus 40-pBR322 recombinant plasmids in COS-1 cells.
Chronic evolution of acute hepatitis type B: prevalence and predictive markers.
Cidofovir.
Clearance of Escherichia coli O157:H7 Infection in Calves by Rectal Administration of Bovine Lactoferrin.
Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance.
Clinical efficacy and bleeding outcomes of tissue plasminogen activator and dornase alfa in pleural space infection with once daily concurrent administration: a retrospective cohort study.
Clinical outcome after early Pseudomonas aeruginosa infection in cystic fibrosis.
Clinical Significance of Inflammatory Biomarkers in Acute Pediatric Diarrhea.
Clinical Trials of Lactoferrin in the Newborn: Effects on Infection and the Gut Microbiome.
Cloning and functional characterization of the origin of lytic-phase DNA replication of rat cytomegalovirus.
Clostridium difficile ribotype 027 is most prevalent among inpatients admitted from long-term care facilities.
Cluster of clinical isolates of epidemic methicillin-resistant Staphylococcus aureus (EMRSA) with a negative deoxyribonuclease (DNase) test-implications for laboratory diagnosis and infection control.
Colicin activity and abortive infection of T5 bacteriophage in Escherichia coli (ColIb).
Colicin Ib does not cause plasmid-promoted abortive phage infection of Escherichia coli K-12.
Colicin insensitivity correlates with higher prevalence of extraintestinal virulence factors among Escherichia coli isolates from skin and soft-tissue infections.
Colicin V production by clinical isolates of Escherichia coli.
Comparison of DNA polymerase activities induced by herpes simplex virus types 1 and 2.
Comparison of human memory CD8 T cell responses to adenoviral early and late proteins in peripheral blood and lymphoid tissue.
Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing.
Complete nucleotide sequence and molecular characterization of two lytic Staphylococcus aureus phages: 44AHJD and P68.
Concurrent Versus Sequential Intrapleural Instillation of Tissue Plasminogen Activator and Deoxyribonuclease for Pleural Infection.
Conjugation-deficient mutants of Escherichia coli distinguish classes of functions of the outer membrane OmpA protein.
Construction and analysis of miniplasmids of the colicin Ib plasmid.
Continuous-release or burst-release of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11) from calcium phosphate bone substitutes.
Correlation of e antigen, DNA polymerase activity, and Dane particles in chronic benign and chronic active type B hepatitis infections.
Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
Cytomegalovirus DNA polymerase inhibition and kinetics.
Cytomegalovirus ileitis in a patient after liver transplantation-differentiating from de novo IBD.
Cytomegalovirus infection in the bone marrow transplant patient.
Cytomegalovirus retinitis, human immunodeficiency virus antibody positivity and normal T helper cell numbers.
Deficiency of the specific granule proteins, R-binder/transcobalamin I and lactoferrin, in plasma and saliva: a new disorder.
Delayed hypersensitivity. I. Induction of hypersensitivity to diphtheria toxin in guinea pigs by infection with Corynebacterium diphtheriae.
Demonstration of N,N-Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens.
Demonstration of the human herpesvirus 6-induced DNA polymerase and DNase.
Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection.
Depletion of regulatory T cells in ongoing paracoccidioidomycosis rescues protective Th1/Th17 immunity and prevents fatal disease outcome.
Detailed polymorphism study on cytomegalovirus DNA polymerase gene to reveal the most suitable genomic targets for quantitative Real-time PCR.
Detecting Candida albicans in human milk.
Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections.
Detection of fungal infections using radiolabeled antifungal agents.
Detection of hepatitis B virus DNA in HBsAg chronic carriers using a liquid phase molecular hybridization (Abbott HBV DNA) and the DNA polymerase assay: comparison of results.
Detection of human parvovirus B19 infection in first-trimester fetal loss.
Development of a TaqMan Based Real-Time Fluorescent Quantitative PCR Assay for Detection of Porcine Cytomegalovirus in Semen.
Development of secretory elements in murine tubotympanum: lysozyme and lactoferrin immunohistochemistry.
Diabetic Lactoferrin Deficient Mice Demonstrates Greater Susceptibility to Experimental Periodontal Disease.
Diagnosis of hepatitis B by Dane particle associated DNA polymerase assay.
Diagnosis of infection with human immunodeficiency virus type 1 by a DNA polymerase chain reaction assay among infants enrolled in the Women and Infants' Transmission Study.
Diagnostic value of blood cytokine concentrations in acute pneumonia.
Diagnostic value of lactoferrin analysis in pleural effusions.
Dietary administration of bovine lactoferrin influences the immune ability of the giant freshwater prawn Macrobrachium rosenbergii (de Man) and its resistance against Aeromonas hydrophila infection and nitrite stress.
Dietary and Protective Factors to Halt or Mitigate Progression of Autoimmunity, COVID-19 and Its Associated Metabolic Diseases.
Dietary Bovine Lactoferrin Reduces Staphylococcus aureus in the Tissues and Modulates the Immune Response in Piglets Systemically Infected with S. aureus.
Dietary Inclusion of Colicin E1 Is Effective in Preventing Postweaning Diarrhea Caused by F18-Positive Escherichia coli in Pigs.
Differential pattern in circulating nitrogen derivatives, lactoferrin, and anti-lactoferrin antibodies in HIV type 1 and HIV type 2 infections.
Differentiation between polymorphisms and resistance associated mutations in the human cytomegalovirus DNA polymerase.
Direct activity of recombinant human lactoferrin against Helicobacter pylori.
Discordant HIV DNA PCR results among infants diagnosed with HIV infection and initiated on ART: a case series.
Discovery and development of a synthetic peptide derived from lactoferrin for clinical use.
Discovery and development of DNA polymerase IIIC inhibitors to treat Gram-positive infections.
Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection.
DNA Polymerase ? Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus.
DNA polymerase and simian virus 40 infection of resting monkey cells: induction of aphidicolin resistant alpha-polymerase.
DNA polymerase and the cell membrane after T4 infection.
DNA polymerases in adenovirus type 5-infected and uninfected KB cells. Induction of an alpha-type DNA polymerase in adenovirus type 5-infected and in fast growing cells.
DNA polymerases in polyoma virus-infected mouse kidney cells.
DNase I cleavage of adenoviral nucleoprotein.
Dornase alfa during lower respiratory tract infection post-lung transplantation: a randomized controlled trial.
Dornase alfa in the treatment of cystic fibrosis in Europe: a report from the Epidemiologic Registry of Cystic Fibrosis.
Dornase alpha inhalations as a treatment option for recurrent lower respiratory tract infections in a child with Sotos syndrome.
Dose effect of bovine lactoferrin fortification on diarrhea and respiratory tract infections in weaned infants with anemia: A randomized, controlled trial.
Dose Escalation Study of Bovine Lactoferrin in Preterm Infants: Getting the Dose Right.
Dose-response trial of lactoferrin in patients with chronic hepatitis C.
Double-blinded, placebo-controlled study to evaluate an antipruritic shampoo for dogs with allergic pruritus.
Dry powders for the inhalation of ciprofloxacin or levofloxacin combined with a mucolytic agent for cystic fibrosis patients.
Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response.
Dynamic and nucleolin-dependent localization of human cytomegalovirus UL84 to the periphery of viral replication compartments and nucleoli.
e-Antigen: a link between immune response and infectivity in hepatitis B?
Early diagnosis of HIV-1-infected infants in Thailand using RNA and DNA PCR assays sensitive to non-B subtypes.
Early inhibitors of human cytomegalovirus: state-of-art and therapeutic perspectives.
Early nucleosome deposition on, and replication of, HSV DNA requires cell factor PCNA.
Early Phase Morphological Lesions and Transcriptional Responses of Bovine Ileum Infected with Mycobacterium avium subsp. paratuberculosis.
Early responding dendritic cells direct the local NK response to control herpes simplex virus 1 infection within the cornea.
Effect of a dietary supplement composed of hydrolyzed milk proteins and vanillin on the reduction of infection and oxidative stress induced by chemotherapy.
Effect of bovine lactoferrin from iron-fortified formulas on diarrhea and respiratory tract infections of weaned infants in a randomized controlled trial.
Effect of bovine lactoferrin in Salmonella ser. Typhimurium infection in mice.
Effect of bovine lactoferrin on Chlamydia trachomatis infection and inflammation.
Effect of change in structure of cohesive ends on aggregating ability and biological activity of bacteriophage lambda DNA.
Effect of colicin V on S. sonnei in vivo and in tissue culture.
Effect of herpes simplex virus type 1 infection on the cellular DNA polymerase activities of mouse cell cultures.
Effect of high-dose methylprednisolone therapy on phagocyte function in systemic lupus erythematosus.
Effect of lactoferricin B, a pepsin-generated peptide of bovine lactoferrin, on Escherichia coli HB101 (pRI203) entry into HeLa cells.
Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin.
Effect of lactoferrin on enteric pathogens.
Effect of lactoferrin on Helicobacter felis induced gastritis.
Effect of lactoferrin on release and bioactivity of Shiga toxins from different Escherichia coli O157:H7 strains.
Effect of lactoferrin on the growth performance, intestinal morphology, and expression of PR-39 and protegrin-1 genes in weaned piglets.
Effect of lactoferrin supplementation on the effectiveness and tolerability of a 7-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection.
Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment.
Effect of Varidase (streptodornase) on biofilm formed by Pseudomonas aeruginosa.
Effectiveness of human, camel, bovine and sheep lactoferrin on the hepatitis C virus cellular infectivity: comparison study.
Effects of feeding probiotics during weaning on infections and antibody responses to diphtheria, tetanus and Hib vaccines.
Effects of lactoferrin in 6 patients with refractory bacterial vaginosis.
Effects of lactoferrin treatment on Escherichia coliEscherichia coli O157:H7 rectal colonization in cattle.
Efficacy of recombinant human deoxyribonuclease I in the hospital management of respiratory syncytial virus bronchiolitis.
Efficient formation of vesicular stomatitis virus pseudotypes bearing the native forms of hepatitis C virus envelope proteins detected after sonication.
Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection.
Electrochemical immunosensor detection of urinary lactoferrin in clinical samples for urinary tract infection diagnosis.
Elevated lactoferrin is associated with moderate to severe Clostridium difficile disease, stool toxin, and 027 infection.
Elevated serum lactoferrin and neopterin are associated with postoperative infectious complications in patients with acute traumatic spinal cord injury.
Emergence of letermovir resistance in a lung transplant recipient with ganciclovir-resistant cytomegalovirus infection.
Emerging drugs for varicella-zoster virus infections.
Emerging therapies for the treatment of Helicobacter pylori infections.
Enteral lactoferrin does not reduce late-onset infection in very preterm infants.
Enteral lactoferrin supplementation did not reduce the risk of late-onset infection in very preterm infants.
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial.
Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT.
Enteric parasites and enteroaggregative Escherichia coli in children from Cañazas County, Veraguas Province, Panama.
Enzymatic activity and bacteriophage infection. III. Increase of desoxyribonuclease.
Enzyme-linked immunosorbent assay for group A Streptococcal anti-DNase B in human sera, using recombinant proteins - Comparison to the DNA methyl green micromethod.
Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia.
Escherichia coli K1 inhibits proinflammatory cytokine induction in monocytes by preventing NF-kappaB activation.
Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates.
Establishment and characterization of fantail goldfish fin (FtGF) cell line from goldfish, Carassius auratus for in vitro propagation of Cyprinid herpes virus-2 (CyHV-2).
Evaluation of serotypes 5 and 8 capsular polysaccharides in protection against Staphylococcus aureus in murine models of infection.
Evaluation of the effects of small interfering RNAs on in vitro replication of feline herpesvirus-1.
Evaluation of the reproductive toxicity of antiretroviral drug loaded lactoferrin nanoparticles.
Evidence for a herpesvirus saimiri-specified DNA polymerase activity which is aphidicolin-resistant and phosphonoacetate-sensitive.
Evidence-based medicine in cystic fibrosis: how should practice change?
Evolution of nucleoside/tide analogues for hepatitis B: Is the ideal drug here yet?
Evolutionary Stabilization of Cooperative Toxin Production through a Bacterium-Plasmid-Phage Interplay.
Experimental antibacterial therapy with puroindolines, lactoferrin and lysozyme in Listeria monocytogenes infected mice.
Exposure to Gastric Acid Inhibitors Increases the Risk of Infection in Preterm Very Low Birth Weight Infants but Concomitant Administration of Lactoferrin Counteracts This Effect.
Expression and characterization of bovine lactoperoxidase by recombinant vaccinia virus.
External quality assessment for the determination of diphtheria antitoxin in human serum.
Extracellular DNA is required for root tip resistance to fungal infection.
Extracts of hamster cells abortively infected with human adenovirus type 12 are competent to support initiation of viral DNA replication.
Extraordinarily potent proinflammatory properties of lactoferrin-containing immunocomplexes against human monocytes and macrophages.
Faecal lactoferrin and calprotectin in patients with Clostridium difficile infection: a case-control study.
Faecal lactoferrin as a predictor of positive faecal culture in south Indian children with acute diarrhoea.
Faecal lactoferrin assay as an adjunct to Clostridium difficile diarrhoea.
Failure of serial human immunodeficiency virus type 1 DNA polymerase chain reactions to identify human immunodeficiency virus type 1 clade A/G.
False negative DNA polymerase chain reaction in an infant with subtype C human immunodeficiency virus 1 infection.
False negative HIV-1 proviral DNA polymerase chain reaction in a patient with primary infection acquired in Thailand.
Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses.
Fimbria-like hemagglutinin of Escherichia coli O75 strains.
Fluctuation in activity of the molecular forms of cellular DNA polymerase during infection by SV40.
Foam fractionation of a dilute solution of bovine lactoferrin.
Formation in the dark, of virus-induced deoxyribonuclease activity in Anacystis nidulans, an obligate photoautotroph.
Formation of Rous associated virus-60: origin of the polymerase gene.
Foxp3+ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.
Frequency of early in utero HIV-1 infection: a blind DNA polymerase chain reaction study on 100 fetal thymuses.
Function, structure and regulation of the vacuolar (H+)-ATPases.
Functional characterization of partially purified Epstein-Barr virus DNA polymerase expressed in the baculovirus system.
Gastric juice levels of lactoferrin and Helicobacter pylori infection.
Genetically modified Lactococcus lactis producing a green fluorescent protein-bovine lactoferrin fusion protein suppresses proinflammatory cytokine expression in lipopolysaccharide-stimulated RAW 264.7 cells.
Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus.
Genomic Analysis of Carbapenem-Resistant Pseudomonas aeruginosa Isolated From Urban Rivers Confirms Spread of Clone Sequence Type 277 Carrying Broad Resistome and Virulome Beyond the Hospital.
Genomic Characterization of Intron-containing T7-like Phage phiL7 of Xanthomonas campestris.
Giardia duodenalis assemblage, clinical presentation and markers of intestinal inflammation in Brazilian children.
Glycation ligand binding motif in lactoferrin. Implications in diabetic infection.
Graphene Oxide and Stabilized Ortho-Silicic Acid as Modifiers of Amnion and Burn Affected Skin: A Comparative Study.
Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trial.
Growth inhibition of Staphylococcus aureus after experimental infection of the udder by high and low concentration of lactoferrin and lysozyme in milk.
Haploid genetic screens in human cells identify host factors used by pathogens.
Have the starting lineup of five for HBV cccDNA synthesis been identified?
Helicobacter pylori and antrum erosion-specific gene expression patterns: the discriminative role of CXCL13 and VCAM1 transcripts.
Helicobacter pylori eradication: a randomized prospective study of triple therapy versus triple therapy plus lactoferrin and probiotics.
Helicobacter pylori infection in clinical practice: probiotics and a combination of probiotics + lactoferrin improve compliance, but not eradication, in sequential therapy.
Heparin-interacting sites of bovine lactoferrin are involved in anti-adenovirus activity.
Hepatitis B e antigen, DNA polymerase activity, and infection of household contacts with hepatitis B virus.
Hepatitis B virus (HBV) reactivation after cytotoxic or immunosuppressive therapy--pathogenesis and management.
Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the 'a' epitope of the surface antigen are sensitive to ganciclovir.
Herpes Simplex Virus-1 infection in human primary corneal epithelial cells is blocked by a stapled peptide that targets processive DNA synthesis.
Herpesvirus DNA polymerases: Structures, functions and inhibitors.
Herpesvirus proteins: DNA polymerase and pyrimidine deoxynucleoside kinase activities in temperature-sensitive mutants of herpes simplex virus type 2.
Heterogeneity in utilization of N-glycosylation sites Asn624 and Asn138 in human lactoferrin: a study with glycosylation-site mutants.
High concentration of human lactoferrin in milk of rhLf-transgenic cows relieves signs of bovine experimental Staphylococcus chromogenes intramammary infection.
High conservation of herpes simplex virus UL5/UL52 helicase-primase complex in the era of new antiviral therapies.
High-level expression of the Epstein-Barr virus alkaline deoxyribonuclease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma.
Highlights in the development of new antiviral agents.
Histatin 5 and human lactoferrin inhibit biofilm formation of a fluconazole resistant Candida albicans clinical isolate.
HIV-regulated diphtheria toxin A chain gene confers long-term protection against HIV type 1 infection in the human promonocytic cell line U937.
Host iron binding proteins acting as niche indicators for Neisseria meningitidis.
Human cytomegalovirus triggers the assembly of AIM2 inflammasome in THP-1-derived macrophages.
Human cytomegalovirus. III. Virus-induced DNA polymerase.
Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children.
Human Herpesvirus 7 induces CD4(+) T-cell death by two distinct mechanisms: necrotic lysis in productively infected cells and apoptosis in uninfected or nonproductively infected cells.
Human hololactoferrin: endocytosis and use as an iron source by the parasite Entamoeba histolytica.
Human lactoferrin activates transcription of IL-1beta gene in mammalian cells.
Human lactoferrin and peptides derived from a surface-exposed helical region reduce experimental Escherichia coli urinary tract infection in mice.
Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria.
Human lactoferrin receptor activity in non-encapsulated Haemophilus influenzae.
Human megakaryocytes have a CD4 molecule capable of binding human immunodeficiency virus-1.
Human milk lactoferrin binds ATP and dissociates into monomers.
Human milk proteins: key components for the biological activity of human milk.
Human neutrophil-specific granule deficiency: a model to assess the role of neutrophil-specific granules in the evolution of the inflammatory response.
Human recombinant lactoferrin is ineffective in the treatment of human Helicobacter pylori infection.
Humoral immune response to human cytomegalovirus DNA polymerase.
Hydrogen peroxide mediated killing of bacteria.
Identification and some properties of a unique DNA polymerase from cells infected with human B-lymphotropic virus.
Identification of a mannoprotein fraction from Candida albicans that enhances human polymorphonuclear leukocyte (PMNL) functions and stimulates lactoferrin in PMNL inhibition of candidal growth.
Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines.
Identification of an atypical CD8 T cell epitope encoded by murine cytomegalovirus ORF-M54 gaining dominance after deletion of the immunodominant antiviral CD8 T cell specificities.
Identification of novel hepatitis B virus therapeutic vaccine candidates derived from polymerase protein.
Identification of receptor binding sites by competitive peptide mapping: phages T1, T5, and phi 80 and colicin M bind to the gating loop of FhuA.
Identification of unprecedented anticancer properties of high molecular weight biomacromolecular complex containing bovine lactoferrin (HMW-bLf).
Immediately early 2 (IE-2) and DNA polymerase SiRNA as virus-specific antiviral against novel transplacental cytomegalovirus strain ALL-03 in vitro.
Immune activation and virologic response to immunization in recent HIV type 1 seroconverters.
Immune modulation by lactoferrin and curcumin in children with recurrent respiratory infections.
Immunization against Anaplasma phagocytophilum Adhesin Binding Domains Confers Protection against Infection in the Mouse Model.
Immunoglobulins, lysozyme and lactoferrin in the teat and udder of the dry cow during endotoxin-induced inflammation.
Immunological aspects of mammary involution.
Immunological evidence for a specific DNA polymerase produced after infection by herpes simplex virus.
Immunomodulatory effects of recombinant lactoferrin during MRSA infection.
Immunonutrition for Preterm Infants.
Impairment of circulating lactoferrin in HIV-1 infection.
Impairment of innate immune responses of airway epithelium by infection with bovine viral diarrhea virus.
Improved methods for producing outer membrane vesicles in Gram-negative bacteria.
Improvements in lung function outcomes in children with cystic fibrosis are associated with better nutrition, fewer chronic pseudomonas aeruginosa infections, and dornase alfa use.
In situ detection of alkaline nuclease activity in cells infected with herpes simplex virus type 1 (HSV-1).
In vitro activity of the novel antibacterial agent ibezapolstat (ACX-362E) against Clostridioides difficile.
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.
In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary Investigation.
In vitro drug combination studies of Letermovir (AIC246, MK-8228) with approved anti-human cytomegalovirus (HCMV) and anti-HIV compounds in inhibition of HCMV and HIV replication.
In vitro experimental infection of primary human hepatocytes with hepatitis B virus.
In vitro recombinants of ground squirrel and woodchuck hepatitis viral DNAs produce infectious virus in squirrels.
In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin.
In vivo synthesis of the periplasmic domain of TonB inhibits transport through the FecA and FhuA iron siderophore transporters of Escherichia coli.
Increase in DNA polymerase alpha in nuclei of chicken kidney cells after avian adenovirus infection.
Increased DNA polymerase activity in Escherichia coli C after infection with phi X174.
Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig.
Induction of lactoferrin gene expression in myeloid or mammary gland cells by human T-cell leukemia virus type 1 (HTLV-1) tax: implications for milk-borne transmission of HTLV-1.
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor.
Infection of the skin caused by Corynebacterium ulcerans and mimicking classical cutaneous diphtheria.
Inflammation and Regeneration in the Dentin-pulp Complex: Net Gain or Net Loss?
Influence of bovine lactoferrin on expression of presentation molecules on BCG-infected bone marrow derived macrophages.
Influence of mother and infant zidovudine treatment duration on the age at which HIV infection can be detected by polymerase chain reaction in infants.
Influence of oral lactoferrin on Mycobacterium tuberculosis induced immunopathology.
Inhibition by interferon of herpes simplex virus thymidine kinase and DNA polymerase in infected and biochemically transformed cells.
Inhibition of cytomegalovirus immediate early gene expression: a therapeutic option?
Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo.
Inhibition of DNA Polymerase from Herpes Simplex Virus-Infected Wi-38 Cells by Phosphonoacetic Acid.
Inhibition of Epstein-Barr virus infection by lactoferrin.
Inhibition of HBV infection by bovine lactoferrin and iron-, zinc-saturated lactoferrin.
Inhibition of Helicobacter pylori infection by bovine milk glycoconjugates in a BAlb/cA mouse model.
Inhibition of herpes simplex virus infection by lactoferrin is dependent on interference with the virus binding to glycosaminoglycans.
Inhibition of herpesvirus multiplication in guinea pig skin by antiviral compounds.
Inhibition of Mayaro virus infection by bovine lactoferrin.
Inhibition of poliovirus type 1 infection by iron-, manganese- and zinc-saturated lactoferrin.
Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.
Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript.
Inhibition of Vascular Endothelial Cell Leak Following Escherichia coli Attachment in an Experimental Model of Sepsis.
Inhibition with lactoferrin of in vitro infection with human herpes virus.
Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states.
Inhibitory activity of bovine lactoferrin against echovirus induced programmed cell death in vitro.
Inhibitory effect of bacteriophage P22 infection on host cell deoxyribonuclease activity.
Inhibitory effects of native and recombinant full-length camel lactoferrin and its N and C lobes on hepatitis C virus infection of Huh7.5 cells.
Initial steps of colicin E1 import across the outer membrane of Escherichia coli.
Insertion derivatives containing segments of up to 16 amino acids identify surface- and periplasm-exposed regions of the FhuA outer membrane receptor of Escherichia coli K-12.
Interaction of colicin E7 with the major coat protein (g8p) may confer limited protection on colicinogenic Escherichia coli against M13 bacteriophage infection.
Interactions between HIV and hepatitis B virus in homosexual men: effects on the natural history of infection.
Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis.
Interventions for primary (intrinsic) tracheomalacia in children.
Intranasal immunization with recombinant outer membrane protein A induces protective immune response against Stenotrophomonas maltophilia infection.
Intranuclear localization of herpes simplex virus immediate-early and delayed-early proteins: evidence that ICP 4 is associated with progeny virus DNA.
Intrapleural Fibrinolytic Therapy versus Early Medical Thoracoscopy for Treatment of Pleural Infection. Randomized Controlled Clinical Trial.
Intrapleural Fibrinolytics and Deoxyribonuclease for Treatment of Indwelling Pleural Catheter-Related Pleural Infection: A Multi-Center Observational Study.
Intrapleural therapy in management of complicated parapneumonic effusions and empyema.
Intrapleural tissue plasminogen activator and deoxyribonuclease for pleural infection. An effective and safe alternative to surgery.
Intrapleural tissue plasminogen activator and deoxyribonuclease therapy for pleural infection.
Investigation of Ctenocephalides felis on domestic dogs and Rickettsia felis infection in the Democratic Republic of Sao Tome and Principe.
Investigation of the enhanced antimicrobial activity of combination dry powder inhaler formulations of lactoferrin.
Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide.
Involvement of bovine lactoferrin moieties in the inhibition of herpes simplex virus type 1 infection.
Involvement of colicin in the limited protection of the colicin producing cells against bacteriophage.
Iron and the risk of infection.
Iron fortification of infant formula.
Iron-binding proteins in sputum of chronic bronchitis patients with Haemophilus influenzae infections.
Is Abortive Infection by Bacteriophage BF23 of Harboring ColIb Plasmids due to Cell Killing by Internally Liberated Colicin Ib?
Is abortive infection by bacteriophage BF23 of Escherichia coli harboring ColIb plasmids due to cell killing by internally liberated colicin Ib?
Isolation and characterization of mutants of colicin plasmids E1 and E2 after Mu bacteriophage infection.
Isolation of a papovavirus with a bipartite genome containing unlinked SV40 and BKV sequences.
Isolation of foscarnet-resistant human cytomegalovirus patterns of resistance and sensitivity to other antiviral drugs.
Key residues of S. flexneri OmpA mediate infection by bacteriophage Sf6.
Killing of Cryptosporidium sporozoites by Lactoferrin.
Kinetics of murine gammaherpesvirus 68 gene expression following infection of murine cells in culture and in mice.
Laboratory diagnosis of clostridium difficile infection. An evaluation of tests for faecal toxin, glutamate dehydrogenase, lactoferrin and toxigenic culture in the diagnostic laboratory.
Lack of IgG4 antibody response to carbohydrate antigens in patients with lymphatic filariasis.
Lactobacilli-lactoferrin interplay in Chlamydia trachomatis infection.
Lactoferricin but not lactoferrin inhibit herpes simplex virus type 2 infection in mice.
Lactoferrin Adsorbed onto Biomimetic Hydroxyapatite Nanocrystals Controlling - In Vivo - the Helicobacter pylori Infection.
Lactoferrin affects the adherence and invasion of Streptococcus dysgalactiae ssp. dysgalactiae in mammary epithelial cells.
Lactoferrin against Staphylococcus aureus Mastitis. Lactoferrin alone or in combination with penicillin G on bovine polymorphonuclear function and mammary epithelial cells colonisation by Staphylococcus aureus.
Lactoferrin and C-reactive protein in response to cytostatic drugs with emphasis on methotrexate.
Lactoferrin and desferrioxamine are ineffective in the treatment of Helicobacter pylori infection and may enhance H. pylori growth and gastric inflammation in mice.
Lactoferrin and host defence: an overview of its immuno-modulating and anti-inflammatory properties.
Lactoferrin and host defense.
Lactoferrin and interleukin-6 interaction in amniotic infection.
Lactoferrin and Its Derived Peptides: An Alternative for Combating Virulence Mechanisms Developed by Pathogens.
Lactoferrin and lactoferricin inhibit Herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir.
Lactoferrin and transferrin in bovine milk in relation to certain physiological and pathological factors.
Lactoferrin as a factor of resistance to infection of the bovine mammary gland.
Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells.
Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo.
Lactoferrin concentration in breast milk of mothers of low-birth-weight newborns.
Lactoferrin concentrations in bovine milk prior to dry-off.
Lactoferrin deficiency as a consequence of a lack of specific granules in neutrophils from a patient with recurrent infections. Detection by immunoperoxidase staining for lactoferrin and cytochemical electron microscopy.
Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Lactoferrin expression by bovine ocular surface epithelia: a primary cell culture model to study lactoferrin gene promoter activity.
Lactoferrin expression in the canine uterus during the estrous cycle and with pyometra.
Lactoferrin feeding augments peritoneal macrophage activities in mice intraperitoneally injected with inactivated Candida albicans.
Lactoferrin for prevention of common viral infections.
Lactoferrin for prevention of neonatal infections.
Lactoferrin for prevention of neonatal sepsis.
Lactoferrin Functionalized Biomaterials: Tools for Prevention of Implant-Associated Infections.
Lactoferrin given in food facilitates dermatophytosis cure in guinea pig models.
Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis.
Lactoferrin in cervical mucus as a biochemical marker for inflammation.
Lactoferrin in Human Milk of Prolonged Lactation.
Lactoferrin in human milk: its role in iron absorption and protection against enteric infection in the newborn infant.
Lactoferrin in intrauterine infection, human parturition, and rupture of fetal membranes.
Lactoferrin in relation to acute phase proteins in sera from newborn infants with severe infections.
Lactoferrin increases both resistance to Salmonella typhimurium infection and the production of antibodies in mice.
Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin.
Lactoferrin inhibits enterovirus 71 infection by binding to VP1 protein and host cells.
Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro.
Lactoferrin inhibits hepatitis B virus infection in cultured human hepatocytes.
Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study.
Lactoferrin inhibits herpes simplex virus type-1 (HSV-1) infection to mouse cornea.
Lactoferrin inhibits the binding of lipopolysaccharides to L-selectin and subsequent production of reactive oxygen species by neutrophils.
Lactoferrin interaction with retinoid signaling: cell growth and apoptosis in mammary cells.
Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-? release in Burkholderia thailandensis infection in vitro.
Lactoferrin markedly inhibits hepatitis C virus infection in cultured human hepatocytes.
Lactoferrin modulation of antigen-presenting-cell response to BCG infection.
Lactoferrin modulation of mycobacterial cord factor trehalose 6-6'-dimycolate induced granulomatous response.
Lactoferrin nanoparticles coencapsulated with curcumin and tenofovir improve vaginal defense against HIV-1 infection.
Lactoferrin prevents invasion and inflammatory response following E. coli strain LF82 infection in experimental model of Crohn's disease.
Lactoferrin protects neonatal rats from gut-related systemic infection.
Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis.
Lactoferrin sequestration and its contribution to iron-deficiency anemia in Helicobacter pylori-infected gastric mucosa.
Lactoferrin stimulates killing and clearance of bacteria but does not prevent mortality of diabetic mice.
Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors.
Lactoferrin-enhanced anoikis: a defense against neonatal necrotizing enterocolitis.
Lactoferrin-mediated protection of the host from murine cytomegalovirus infection by a T-cell-dependent augmentation of natural killer cell activity.
Lactoferrin: A Critical Player in Neonatal Host Defense.
Lactoferrin: a modulator of immune and inflammatory responses.
Lactoferrin: an iron-binding antimicrobial protein against Escherichia coli infection.
Lactoferrin: Antimicrobial activity and therapeutic potential.
Lactoferrin: Balancing Ups and Downs of Inflammation Due to Microbial Infections.
Lactoferrin: role in iron homeostasis and host defense against microbial infection.
Langerin+ CD8?+ Dendritic Cells Drive Early CD8+ T Cell Activation and IL-12 Production During Systemic Bacterial Infection.
Levels of salivary lysozyme, lactoperoxidase, and lactoferrin in diabetic hamsters.
Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease.
Limited role of CD4+Foxp3+ regulatory T cells in the control of experimental cerebral malaria.
Limited role of regulatory T cells during acute Theiler virus-induced encephalitis in resistant C57BL/6 mice.
Livestock trypanosomosis in Uganda: parasite heterogeneity and anaemia status of naturally infected cattle, goats and pigs.
Local dornase alfa treatment reduces NETs-induced airway obstruction during severe RSV infection.
Location of the abi, col and imm genes on pHU011, a colicin Ib plasmid derivative.
Long-term follow-up of chronic hepatitis C patients treated with oral lactoferrin for 12 months.
Long-term inhibition of clinical and laboratory human immunodeficiency virus strains in human T-cell lines containing an HIV-regulated diphtheria toxin A chain gene.
Loss of a phosphorylated form of transcription factor CREB/ATF in poliovirus-infected cells.
Lysozyme in cervical mucus of patients with chorioamnionitis.
M860, a Monoclonal Antibody against Human Lactoferrin, Enhances Tumoricidal Activity of Low Dosage Lactoferrin via Granzyme B Induction.
Main properties of duck hepatitis B virus DNA polymerase: comparison with the human and woodchuck hepatitis B virus DNA polymerases.
Management of community-acquired pneumonia in immunocompetent adults: updated Swedish guidelines 2017.
Management of parapneumonic effusions and empyema.
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics.
Maternal transmission of duck hepatitis B virus in pedigree Pekin ducks.
Measurement of fecal lactoferrin for rapid diagnosis of enterohemorrhagic Escherichia coli infection.
Measurement of urinary lactoferrin as a marker of urinary tract infection.
Mechanisms of inhibition of herpes simplex virus type 2 growth by 28-mer phosphorothioate oligodeoxycytidine.
Membrane damage in abortive infections of colicin Ib-containing Escherichia coli by bacteriophage T5.
Metal complexes of bovine lactoferrin inhibit in vitro replication of herpes simplex virus type 1 and 2.
Microsporidiosis in South Africa: PCR detection in stool samples of HIV-positive and HIV-negative individuals and school children in Vhembe district, Limpopo Province.
Milk lactoferrin in heifers: influence of health status and stage of lactation.
Minute virus of mice-induced modification of the murine DNA polymerase alpha-primase complex permits the salt-induced dissociation of 12S DNA primase and 10S DNA polymerase alpha components.
Modifying Effect of Colicin on Experimental Shigella Keratoconjunctivitis.
Molecular analysis of non-specific protection against murine malaria induced by BCG vaccination.
Molecular analysis of two novel Neisseria gonorrhoeae virulent components: the macrophage infectivity potentiator and the outer membrane protein A.
Molecular cloning, promoter analysis and SNP identification of Italian Nicastrese and Saanen lactoferrin gene.
Molecular Mechanisms Behind Anti SARS-CoV-2 Action of Lactoferrin.
Molecular modeling and expression of the Litopenaeus vannamei proliferating cell nuclear antigen (PCNA) after white spot syndrome virus shrimp infection.
Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.
Mortality in the first 2 years among infants born to human immunodeficiency virus-infected women in Harare, Zimbabwe.
Mouse cytomegalovirus reactivation in severe combined immune deficient mice after implantation of latently infected salivary gland.
Moving Past Ganciclovir and Foscarnet: Advances in CMV Therapy.
Mucosal lactoferrin response to genital tract infections is associated with iron and nutritional biomarkers in young Burkinabé women.
Multidrug resistant Clostridium difficile ribotype 027 in southwestern Virginia, 2007 to 2013.
Multifunctional iron bound lactoferrin and nanomedicinal approaches to enhance its bioactive functions.
Multiplex PCR for the diagnosis of red sea bream iridoviruses isolated in Korea.
Mycobacterium leprae infection and serum lactoferrin levels.
N-terminal stretch Arg2, Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA.
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis.
Neonatal sepsis: new preventive strategies.
Neutrophil and eosinophil granulocytes in bacterial infection: sequential studies of cellular and serum levels of granule proteins.
Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype.
Neutrophil lactoferrin content in viral infections.
Neutrophil-macrophage cooperation in the host defence against mycobacterial infections.
Neutrophilic granulocytes in acute bacterial infection. Sequential studies on lysozyme, myeloperoxidase and lactoferrin.
New deoxyribonuclease activity after bacteriophage P22 infection.
New Developments in the Management of Cytomegalovirus Infection After Transplantation.
NEW POSSIBILITIES OF PREVENTION OF INFECTION IN THE NEWBORN.
Nitrogen and protein components of human milk.
NMR characterization of a multi-valent conjugate vaccine against Neisseria meningitidis A, C, W, Y and Haemophilus influenzae b infections.
No in vivo effect of trisodium phosphonoformate on woodchuck hepatitis virus production.
Non-oncologic applications of radiolabeled peptides in nuclear medicine.
Nonmalignant disease associated with human herpesvirus 8 reactivation in patients who have undergone autologous peripheral blood stem cell transplantation.
Nonspecific oral immunity in individuals with HIV infection.
Noticeable differences in bacterial defence on tonsillar surfaces between bacteria-induced and virus-induced acute tonsillitis.
Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient.
Nuclear activity from F9 embryonal carcinoma cells binding specifically to the enhancers of wild-type polyoma virus and PyEC mutant DNAs.
Nuclear import of HSV-1 DNA polymerase processivity factor UL42 is mediated by a C-terminally located bipartite nuclear localization signal.
Nuclease sensitivity of adenovirus type 2 chromatin in lytic infection.
Nutritional interventions to reduce rates of infection, necrotizing enterocolitis and mortality in very preterm infants.
Nutritional roles of lactoferrin.
Occurrence of Clostridium difficile ribotype 027 in hospitals of Silesia, Poland.
OmpA-like proteins of Porphyromonas gingivalis contribute to serum resistance and prevent Toll-like receptor 4-mediated host cell activation.
Optimizing treatment policies and improving care: impact on outcome in patients with cystic fibrosis.
Oral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Oral lactoferrin prevents body weight loss and increases cytokine responses during herpes simplex virus type 1 infection of mice.
Oral lactoferrin protects against experimental candidiasis in mice.
Oral lactoferrin treatment resolves amoebic intracecal infection in C3H/HeJ mice.
Osteomyelitis prevention in rabbits using antimicrobial peptide hLF1-11- or gentamicin-containing calcium phosphate cement.
Outcome of HIV-infected Pregnant Women and Their Offspring in Barbados: A Five-year Study.
Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection.
Overproduction of the toxic protein, bovine pancreatic DNaseI, in Escherichia coli using a tightly controlled T7-promoter-based vector.
Overview of Lactoferrin as a Natural Immune Modulator.
Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo.
PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium.
PCR Results and PMTCT Treatment Outcomes among HIV-Exposed Infants in a Tertiary Hospital in Nigeria, 2010-2014.
Pediatric diagnosis of human immunodeficiency virus type 1 infection: the problem of false negative DNA polymerase chain reaction results.
Pediatric diarrhea in southern Ghana: etiology and association with intestinal inflammation and malnutrition.
Pediatric viral human immunodeficiency virus type 1 RNA levels, timing of infection, and disease progression in African HIV-1-infected children.
Penetration of a bacteriophage into Bacillus subtilis: blockage of infection by deoxyribonuclease.
Performance of clinical algorithms for HIV-1 diagnosis and antiretroviral initiation among HIV-1-exposed children aged less than 18 months in Kenya.
Perinatal transmission of the hepatitis B virus and of the HBV-associated delta agent from mothers to offspring in northern Italy.
Persistent infection of primary human cell cultures with rubella variant carrying DNA Polymerase activity.
Pilot study of dornase alfa (Pulmozyme) therapy for acquired ventilator-associated infection in preterm infants.
Plasma lactoferrin as a marker of infection in elderly individuals.
Plasma lactoferrin levels in newborn preterm infants: effect of infection.
Plasmodium falciparum: inhibition in vitro with lactoferrin, desferriferrithiocin, and desferricrocin.
Polymerase chain reaction detection and inducible nitric-oxide synthase expression of Leishmania major in mice inoculated by two different routes.
Polymerase chain reaction for diagnosis of human immunodeficiency virus infection in infancy in low resource settings.
Polymorphisms in the promoter region of the bovine lactoferrin gene influence milk somatic cell score and milk production traits in Chinese Holstein cows.
Porcine and bovine lactoferrin inhibit growth of porcine enterotoxigenic E. coli and degrades their virulence factors.
Potential antimicrobial effects of human lactoferrin against oral infection with Listeria monocytogenes in mice.
Potential for combined therapy with 348U87, a ribonucleotide reductase inhibitor, and acyclovir as treatment for acyclovir-resistant herpes simplex virus infection.
Potential of lactoferrin to prevent antibiotic-induced Clostridium difficile infection.
Potential Therapeutic Approaches Against Brain Diseases Associated with Cytomegalovirus Infections.
Prediction of microbial infection and mortality in medical patients with fever: plasma procalcitonin, neutrophilic elastase-alpha1-antitrypsin, and lactoferrin compared with clinical variables.
Preliminary observations on lactoferrin secretion in human vaginal mucus: variation during the menstrual cycle, evidence of hormonal regulation, and implications for infection with Neisseria gonorrhoeae.
Preliminary report of in vitro and in vivo effectiveness of dornase alfa on SARS-CoV-2 infection.
Presence of HBeAg, DNA polymerase activity, Dane particle in different categories of HBsAg carriers and evidence of hepatitis type B infection in their family contacts.
Preservation of natural endothelial cytopathogenicity of cytomegalovirus by propagation in endothelial cells.
Prevalence of HSV1/2 Congenital Infection Assessed Through Genome Detection on Dried Blood Spot in Individuals with Autism Spectrum Disorders.
Prevalence of oral Candida in the first year of life.
Prevention of Cytomegalovirus Transmission via Breast Milk in Extremely Low Birth Weight Infants.
Preventive effect of recombinant human lactoferrin in a rabbit preterm delivery model.
Production of coagulase, deoxyribonuclease and heat-stable deoxyribonuclease by canine isolates of staphylococci.
Properties of adenoviral DNA bound to the nuclear matrix.
Properties of oncornavirus RNA-directed DNA polymerase, the RNA template, and the intracellular products formed early during infection and cell transformation.
Properties of the DNA polymerase induced by Marek's disease herpesvirus, strain GA, upon infection of duck embryo fibroblasts.
Properties of the FhuA channel in the Escherichia coli outer membrane after deletion of FhuA portions within and outside the predicted gating loop.
Prophylactic effect of bovine lactoferrin against acute toxoplasmosis in immunocompetent and immunosuppressed mice.
Prophylactic lactoferrin for preventing late-onset sepsis and necrotizing enterocolitis in preterm infants: A PRISMA-compliant systematic review and meta-analysis.
Prophylaxis with lactoferrin, a novel antimicrobial agent, in a neonatal rat model of coinfection.
Protection against infections by oral lactoferrin: evaluation in animal models.
Protection of infant rats from Haemophilus influenzae type b infection by antiserum to purified outer membrane protein a.
Protective Action of L. salivarius SGL03 and Lactoferrin against COVID-19 Infections in Human Nasopharynx.
Protective effects of lactoferrin chimera and bovine lactoferrin in a mouse model of enterohaemorrhagic Escherichia coli O157:H7 infection (1) (1) This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process.
Protective effects of lactoferrin in Escherichia coli-induced bacteremia in mice: relationship to reduced serum TNF alpha level and increased turnover of neutrophils.
Protein regulation strategies of the mouse spleen in response to Babesia microti infection.
Provirus copy number to predict disease progression in asymptomatic human immunodeficiency virus type 1 infection.
Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation.
Purification and characterization of varicella-zoster virus-induced DNA polymerase.
Quadruple therapy with lactoferrin for Helicobacter pylori eradication: a randomised, multicentre study.
Quantitative Fecal Lactoferrin as a Biomarker for Severe Clostridium difficile Infection in Hospitalized Patients.
Quantitative fecal lactoferrin in toxin-positive and toxin-negative Clostridium difficile specimens.
Radiotracers for fungal infection imaging.
Randomized Controlled Trial of Talactoferrin Oral Solution in Preterm Infants.
Randomly amplified polymorphic DNA polymerase chain reaction assay for molecular epidemiologic investigation of Pasteurella pneumotropica in laboratory rodent colonies.
Rapid chromatin remodeling of Toll-like receptor 2 promoter during infection of macrophages with Mycobacterium avium.
Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity.
Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat.
Recent advances in prevention of sepsis in the premature neonates in NICU.
Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier.
Recombinant human DNase in children with airway malacia and lower respiratory tract infection.
Recombinant human lactoferrin expressed in glycoengineered Pichia pastoris: effect of terminal N-acetylneuraminic acid on in vitro secondary humoral immune response.
Recombinant human lactoferrin is effective in the treatment of Helicobacter felis-infected mice.
Recombinant outer membrane protein A induces a protective immune response against Escherichia coli infection in mice.
Recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonatal mice from a lethal challenge with enterovirus type 71.
Recruitment of dendritic cells is responsible for intestinal epithelial damage in the pathogenesis of necrotizing enterocolitis by Cronobacter sakazakii.
Recurrent neonatal group B streptococcal disease associated with infected breast milk.
Reducing suspicion of sexual abuse in paediatric chlamydial conjunctivitis using ompA genotyping.
Relation of cell growth and colicin tolerance to vitamin B12 uptake in Escherichia coli.
Relation of lactoferrin levels in gastric mucosa with Helicobacter pylori infection and with the degree of gastric inflammation.
Relationship between HBV-specific DNA polymerase and HBe antigen/antibody system in chronic HBV infection: factors determining selection of patients and outcome of antiviral therapy.
Replication of animal viruses in differentiating muscle cells: vaccinia and herpes simplex virus type 1.
Replication of herpes simplex virus DNA: localization of replication recognition signals within defective virus genomes.
Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein.
Resistance of chimpanzees immunized with recombinant gp120SF2 to challenge by HIV-1SF2.
Response to a Haemophilus influenzae type b diphtheria CRM197 conjugate vaccine in children with a defect of antibody production to Haemophilus influenzae type b polysaccharide.
Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.
Reversible inhibition of the induction of DNA polymerase of herpes simplex virus type 2 in HeLa cells.
Ribotype 027 Clostridium difficile infections with measurable stool toxin have increased lactoferrin and are associated with a higher mortality.
Risk factors for in utero and intrapartum transmission of HIV.
Role of biomarkers in the diagnosis of inflammatory bowel disease.
Role of CXC chemokine receptor type 4 as a lactoferrin receptor.
Role of endogenous interferon and LPS in the immunomodulatory effects of bovine lactoferrin in murine peritoneal macrophages.
Root Border Cells and Their Role in Plant Defense.
Salivary lactoferrin is transferred into the brain via the sublingual route.
Screening the anti infectivity potentials of native N- and C-lobes derived from the camel lactoferrin against hepatitis C virus.
Selected Immunological Mediators and Cervical Microbial Signatures in Women with Chlamydia trachomatis Infection.
Selective inhibition of adenovirus type 2 early region II and III transcription by an anisomycin block of protein synthesis.
Sensitivity and specificity of a DNA polymerase chain reaction nonisotopic-based detection method for the confirmation of infection with human T-lymphotropic virus types I and II.
Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA.
Seroepidemiology of diphtheria and pertussis in Chongqing, China: serology-based evidence of Bordetella pertussis infection.
Seroprevalence of antibodies against Pkn1, a novel potential immunogen, in Chlamydia trachomatis-infected Macaca nemestrina and human patients.
Serum resistance among Escherichia coli strains causing urinary tract infection in relation to O type and the carriage of hemolysin, colicin, and antibiotic resistance determinants.
Serum-levels of lactoferrin, lysozyme and myeloperoxidase in normal, infection-prone and leukemic children.
Signal-boosted qualitative ultrasensitive p24 antigen assay for diagnosis of subtype C HIV-1 infection in infants under the age of 2 years.
Simian varicella virus gene 28 and 29 promoters share a common upstream stimulatory factor-binding site and are induced by IE62 transactivation.
Single nucleotide polymorphisms (SNPs) in human lactoferrin gene.
Specific binding of lactoferrin to Escherichia coli isolated from human intestinal infections.
Steady-state plasma lactoferrin levels in relation to infections and complications of sickle cell disease.
Stimulus-dependent impairment of the neutrophil oxidative burst response in lactoferrin-deficient mice.
Streptokinase and streptodornase in the treatment of surgical infections.
Structural characterization of the interaction of human lactoferrin with calmodulin.
Structural features of very fast sedimenting DNA formed by gene 49 defective T4.
Structure and biological actions of lactoferrin.
Structure of the bovine lactoferrin-encoding gene and its promoter.
Structure-Driven Discovery of ?,?-Diketoacid Inhibitors Against UL89 Herpesvirus Terminase.
Studies of bronchial secretion. The influence of inflammatory response and bacterial infection.
Studies on the mode of action of diphtheria toxin. VI. Inhibition of protein synthesis induced by local infection with toxingenic Corynebacterium diphtheriae.
Subcapsular sinus macrophages limit acute gammaherpesvirus dissemination.
Successful management of pleural infection with very low dose intrapleural tissue plasminogen activator/deoxyribonuclease regime.
Sulfamoylbenzamide derivatives inhibit the assembly of hepatitis B virus nucleocapsids.
Sulfated derivatives of Escherichia coli K5 capsular polysaccharide are potent inhibitors of human cytomegalovirus.
Summary Protocol for a Multi-Centre Randomised Controlled Trial of Enteral Lactoferrin Supplementation in Newborn Very Preterm Infants (ELFIN).
Surface functionalization of titanium substrates with Deoxyribonuclease I inhibit peri-implant bacterial infection.
Susceptibility of domestic birds to lymphoproliferative disease virus (LPDV) of turkeys.
Suspension of milking in dairy cows produces a transient increase in milk lactoferrin concentration and yield after resumption of milking.
Synergistic antibacterial efficacies of the combination of bovine lactoferrin or its hydrolysate with probiotic secretion in curbing the growth of methicillin-resistant Staphylococcus aureus (MRSA).
Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates.
Synthesis and activity of p-azidobenzoyloxyferricrocin, a photoactivatable analog of ferrichrome.
Synthesis of esters of phosphonoformic acid and their antiherpes activity.
Synthesis, structure and function of avian sarcoma virus-specific DNA in permissive and nonpermissive cells.
Synthetic bovine lactoferrin peptide Lfampin kills Entamoeba histolytica trophozoites by necrosis and resolves amoebic intracecal infection in mice.
Systemic and mucosal levels of lactoferrin in very low birth weight infants supplemented with bovine lactoferrin.
T lymphocytes among HIV-infected and -uninfected infants: CD4/CD8 ratio as a potential tool in diagnosis of infection in infants under the age of 2 years.
Tandem repeats of lactoferrin-derived anti-hepatitis C virus peptide enhance antiviral activity in cultured human hepatocytes.
TaqMan real-time PCR assay based on DNA polymerase gene for rapid detection of Orf infection.
Targeting the pseudorabies virus DNA polymerase processivity factor UL42 by RNA interference efficiently inhibits viral replication.
Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.
The anti-papillomavirus activity of human and bovine lactoferricin.
The antibacterial activity of lactoferrin and neonatal E. coli infections. A selective and critical review.
The appearance of DNase I hypersensitive sites at the 5' end of the late SV40 genes is correlated with the transcriptional switch.
The association between colicinogenicity and pathogenesis among uropathogenic isolates of Escherichia coli.
The concerted action of lactoferrin and bacteriophages in the clearance of bacteria in sublethally infected mice.
The deoxyribonuclease induced after infection of Escherichia coli by bacteriophage T5. I. Characterization of the enzyme as a 5'-exonuclease.
The deoxyribonuclease induced after infection of Escherichia coli by bacteriophage T5. II. Role of the enzyme in replication of the pahge deoxyribonucleic acid.
The deoxyribonuclease induced after infection of KB cells by herpes simplex virus type 1 or type 2. I. Purification and characterization of the enzyme.
The deoxyribonucleases of Escherichia coli. VII. A deoxyribonuclease induced by infection with phage T-5.
The detection of DNA polymerase activity in the diagnosis of HBV infection.
The development of mammary secretory immunity in the human newborn.
The duck enteritis virus early protein, UL13, found in both nucleus and cytoplasm, influences viral replication in cell culture.
The effect of bovine lactoferrin and lactoferricin B on the ability of feline calicivirus (a norovirus surrogate) and poliovirus to infect cell cultures.
The effect of lactoferrin on oral bacterial attachment.
The effect of polyamines on herpes simplex virus type 1 DNA polymerase purified from infected baby hamster kidney cells (BHK-21/C13).
The effect of recombinant human lactoferrin from the milk of transgenic cows on Salmonella enterica serovar typhimurium infection in mice.
The effect of recombinant human lactoferrin on growth and the antibiotic susceptibility of the cystic fibrosis pathogen Burkholderia cepacia complex when cultured planktonically or as biofilms.
The effect of two artificial salivas on the adhesion of Candida albicans to heat-polymerized acrylic resin.
The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD.
The expression of ferritin, lactoferrin, transferrin receptor and solute carrier family 11A1 in the host response to BCG-vaccination and Mycobacterium tuberculosis challenge.
The infant and hepatitis B virus infection.
THE INFLUENCE OF BACTERIOCINS ON RESISTANCE TO INFECTION BY GRAM-NEGATIVE BACTERIA. I. THE EFFECT OF COLICIN ON BACTERICIDAL POWER OF BLOOD.
The influence of bacteriocins on resistance to infection by gram-negative bacteria. II. Colicin action, transfer of colicinogeny, and transfer of antibiotic resistance in urinary infections.
The Innate Immune Glycoprotein Lactoferrin Represses the Helicobacter pylori cag Type IV Secretion System.
The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis.
The natural food grade inhibitor, lacticin 3147, reduced the incidence of mastitis after experimental challenge with Streptococcus dysgalactiae in nonlactating dairy cows.
The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques.
The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
The Prevalence of Occult Hepatitis B Infection among Blood Donors in Lagos, Nigeria.
The protective effects of lactoferrin against murine norovirus infection through inhibition of both viral attachment and replication.
The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin.
The regulation by iron of the synthesis of adhesins and cytoadherence levels in the protozoan Trichomonas vaginalis.
The Role of Lactoferrin in Gastrointestinal and Immune Development and Function: A Preclinical Perspective.
The significance of antibody to hepatitis C virus in patients with chronic hepatitis B.
The significance of cytomegalovirus in children with pneumonia admitted for mechanical ventilation.
The synthetic N-terminal peptide of human lactoferrin, hLF(1-11), is highly effective against experimental infection caused by multidrug-resistant Acinetobacter baumannii.
The Use of Dornase Alfa in the Management of COVID-19-Associated Adult Respiratory Distress Syndrome.
Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections.
Therapeutic strategies for a functional cure of chronic hepatitis B virus infection.
Tissue Plasminogen Activator Potently Stimulates Pleural Effusion via an MCP-1 Dependent Mechanism.
Transcriptome Analysis of Kaposi's Sarcoma-Associated Herpesvirus during De Novo Primary Infection of Human B and Endothelial Cells.
Transgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection.
Transient expression of the vaccinia virus DNA polymerase is an intrinsic feature of the early phase of infection and is unlinked to DNA replication and late gene expression.
Transport of iron across the outer membrane.
Treg depletion attenuates the severity of skin disease from ganglionic spread after HSV-2 flank infection.
Tumor necrosis factor-alpha increases lactoferrin transcytosis through the blood-brain barrier.
Type dependent patterns of human adenovirus persistence in human T-lymphocyte cell lines.
Ultrastructural and cytochemical study of cell wall modification by lactoferrin, lactoferricin and penicillin G against Staphylococcus aureus.
Unintentional intramuscular administration of tPA/DNase for pleural infection.
Unique epitopes of lactoferrin expressed in human cytotrophoblasts involved in immunologic reactions.
Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence.
Use and endocytosis of iron-containing proteins by Entamoeba histolytica trophozoites.
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.
Use of intrapleural tissue plasminogen activator and deoxyribonuclease in pleural space infections: an update on alternative regimens.
Usefulness of a Helicobacter pylori stool antigen test for diagnosing H. pylori infected C57BL/6 mice.
Utility of the bacteriophage RB69 polymerase gp43 as a surrogate enzyme for herpesvirus orthologs.
Various routes of administration of (99m)Tc-labeled synthetic lactoferrin antimicrobial peptide hLF 1-11 enables monitoring and effective killing of multidrug-resistant Staphylococcus aureus infections in mice.
Viral alkaline nuclease in intranuclear dense bodies induced by herpes simplex infection.
Viral and cellular deoxyribonucleases are associated with herpes simplex virus replicative intermediates.
Virological and serological investigation of Equid herpesvirus 1 infection in New Zealand.
Virtual screening, identification, and biochemical characterization of novel inhibitors of the reverse transcriptase of human immunodeficiency virus type-1.
Virulence factor-dependent basolateral invasion of choroid plexus epithelial cells by pathogenic Escherichia coli in vitro.
Virulence factors of Escherichia coli in urinary isolates.
Virulence factors of uropathogenic Escherichia coli from a university hospital in Ribeirão Preto, São Paulo, Brazil.
Visualization of Neutrophil Extracellular Traps and Fibrin Meshwork in Human Fibrinopurulent Inflammatory Lesions: III. Correlative Light and Electron Microscopic Study.
Warding Off Recurrent Yeast and Bacterial Vaginal Infections: Lactoferrin and Lactobacilli.
What is the performance of novel synovial biomarkers for detecting periprosthetic joint infection in the presence of inflammatory joint disease?
When is it time for reverse transcription to start and go?
Yersiniabactin reduces the respiratory oxidative stress response of innate immune cells.
[A new approach to clinical and laboratory diagnosis of systemic and local soft tissue infections]
[Acyclovir-resistance zona in a immunocompromised HIV seronegative patient]
[Acyclovir-resistant perineal HSV infection revealing chronic lymphoid leukaemia].
[Changes in the bacteriostatic activity of lactoferrin during lactation and following experimental infection of the udder with Staphylococcus aureus]
[Characteristic of biological properties of Neisseria gonorrhoeae and parameters of local immunity during urogenital gonococcal infection]
[Colicin as a factor of Escherichia and the Shigella antagonism during dysentery infection. I. Preparation of apurified colicin V preparation and study of its activity]
[Colicin genotype characteristics of pathogenic Escherichia circulating in the environment]
[Combination of demethylchlortetracycline with streptokinase and streptodornase in the treatment of human infections]
[Combined action of levofloxacin and DNAase on biofilms of urogenital infection pathogens].
[Corynebacterium diphtheriae nontoxigenic strain carrying the gene of diphtheria toxin]
[Cytochemical identification of acid desoxyribonuclease in blood cell cytoplasm. 2. Activity of acid desoxyribonuclease in leukocyte cytoplasm in the course of acute infections]
[Desoxyribonuclease I activity of the hepato-splenic and cerebral tissue of rats during experimental infection with encephalomyocarditis virus]
[Diagnostic value of Diamed AG latex gel kit for detection of diphtheria toxin]
[Diphtheria toxin: the molecular biology of an infection]
[Emergency laboratory diagnosis of diphtheria]
[Evaluation of the influence of systemic enzyme therapy on immune reactions in genitourinary chlamydia infection].
[Frequency of colicin and hemolysins in Escherichia coli isolated from pregnant patients with urinary tract infection, symptomatic and asymptomatic]
[Hepatitis B virus DNA polymerase activity in various clinical forms of HBV infection]
[Herpes simplex virus infection: an overview of the problem, pharmacologic therapy and dietary measures].
[Lactoferrin and respiratory tract infections in infancy]
[Lactoferrin in cervical mucus of patients with chorioamnionitis]
[Mathematical model of the infection process in diphtheria for determining the therapeutic dose of antitoxic anti-diphtheria serum]
[Modifications of desoxyribonuclease I activity of the blood and hepatic and splenic tissues of the mouse in the course of experimental infection due to the MHV-3 virus]
[Nature, character, occurrence, and demonstration of hepatitis B antigens (author's transl)]
[Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis]
[Presence of lactoferrin (LF) in lymphocutaneous sporotrichosis. Yeast-bound antimicrobial peptide].
[Presence of lactoferrin in faeces as the indicator of Clostridium difficile in pediatric patients].
[Pulmonary medicine. Four major papers in 2010-2011].
[Recent advances of basic research and clinical application of lactoferrin as an antiviral reagent against chronic hepatitis C]
[Relation of iron supply and iron metabolism to infectious diseases and parasitoses and the competence of the immune system]
[Serum DNAase I activity as a protective factor in infections caused by DNA-genome viruses]
[Specificity of antibodies to diphtheria toxin subunits in children with various forms of diphtheria infections]
[Streptokinase and streptodornase in surgical infections.]
[The comparative characteristic of immune status of males with bacterial inflammatory urogenital pathology of different etiology in the city of Orenburg].
[The initial phases of an infection by beta-hemolytic group A streptococci in the rabbit with special reference to streptodornase and antistreptodornase (author's transl)]
[The proteins of fast phase of inflammation in prognosis of condition of newborn in case of pregnancy complicated by hydramnion and under the risk of intrauterine infection].
[The structural-functional organization of the diphtheria toxin]
[The use of plasma lactoferrin in the diagnosis of pyonecrotic infections of soft tissues and sepsis]
[Use of fibrinolytics and deoxyribonuclease in patients with pleural infection].
Infectious Bovine Rhinotracheitis
Purification of the infectious bovine rhinotracheitis virus alkaline deoxyribonuclease expressed in Escherichia coli.
Infectious Mononucleosis
Causes for massive bacterial colonization on mucosal membranes during infectious mononucleosis: implications for acute otitis media.
Immunocytochemical localization of lysozyme and lactoferrin attached to surface bacteria of the palatine tonsils during infectious mononucleosis.
Noticeable differences in bacterial defence on tonsillar surfaces between bacteria-induced and virus-induced acute tonsillitis.
[Therapeutic effectiveness of deoxyribonuclease in infectious mononucleosis]
Infertility
Concentration of lactoferrin and interleukin-6 in cervical mucus from patients being treated for infertility.
Myeloperoxidase and lactoferrin expression in semen fluid: Novel markers of male infertility risk?
Sterility Testing of Stem Cell Products by Broad-Range Bacterial 16S Ribosomal DNA Polymerase Chain Reaction.
The second intron of AGAMOUS drives carpel- and stamen-specific expression sufficient to induce complete sterility in Arabidopsis.
[Risk factors for violations of the fertility in men living in urban areas].
Infertility, Male
Ascorbic acid as DNase I inhibitor in prevention of male infertility.
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.
Myeloperoxidase and lactoferrin expression in semen fluid: Novel markers of male infertility risk?
Rutin as Deoxyribonuclease I Inhibitor.
Inflammatory Bowel Diseases
A Meta-Analysis of the Utility of C-Reactive Protein, Erythrocyte Sedimentation Rate, Fecal Calprotectin, and Fecal Lactoferrin to Exclude Inflammatory Bowel Disease in Adults With IBS.
Achieving Target Infliximab Drug Concentrations Improves Blood and Fecal Neutrophil Biomarkers in Crohn's Disease.
Advantages of fecal lactoferrin measurement during granulocyte and monocyte adsorptive apheresis therapy in ulcerative colitis.
Antineutrophil cytoplasm autoantibodies against bactericidal/permeability-increasing protein in inflammatory bowel disease.
Antineutrophil cytoplasmic antibodies (ANCAs) in patients with inflammatory bowel disease show no correlation with proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G and lysozyme: a Singapore study.
Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Disease and Collagenous Colitis: No Association with Lactoferrin, ?-Glucuronidase, Myeloperoxidase, or Proteinase 3.
Antineutrophil cytoplasmic antibodies in primary sclerosing cholangitis: defined specificities may be associated with distinct clinical features.
Antineutrophil cytoplasmic autoantibodies in inflammatory bowel diseases.
Are calprotectin and lactoferrin equivalent screening tests for inflammatory bowel disease?
Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis?
C-Reactive Protein, Fecal Calprotectin, and Stool Lactoferrin for Detection of Endoscopic Activity in Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review and Meta-Analysis.
Clinical utility of calprotectin and lactoferrin as markers of inflammation in patients with inflammatory bowel disease.
Clinical utility of calprotectin and lactoferrin in patients with inflammatory bowel disease: is there something new from the literature?
Diagnostic accuracy of fecal lactoferrin for inflammatory bowel disease: a meta-analysis.
Diagnostic utility of quantitative cytomegalovirus DNA polymerase chain reaction in intestinal biopsies from patients with inflammatory bowel disease.
Diagnostics and prognostics of inflammatory bowel disease with fecal neutrophil-derived biomarkers calprotectin and lactoferrin.
Differential excretion of leucocyte granule components in inflammatory bowel disease: implications for pathogenesis.
Distribution of lactoferrin and 60/65 kDa heat shock protein in normal and inflamed human intestine and liver.
Enzymes in feces: useful markers of chronic inflammatory bowel disease.
Erratum to: Timely Monitoring of Inflammation by Fecal Lactoferrin Rapidly Predicts Therapeutic Response in Inflammatory Bowel Disease.
Evaluation of point-of-care test calprotectin and lactoferrin for inflammatory bowel disease among children with chronic gastrointestinal symptoms.
Faecal calprotectin and lactoferrin as markers for monitoring disease activity and predicting clinical recurrence in patients with Crohn's disease after ileocolonic resection: A prospective pilot study.
Faecal lactoferrin, capsule endoscopy and Crohn's disease. Is there a three way relationship? A pilot study.
Fecal biomarkers in inflammatory bowel disease.
Fecal calprotectin and lactoferrin as noninvasive markers of pediatric inflammatory bowel disease.
Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapse.
Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease.
Fecal Lactoferrin and Other Stool Markers during Normal Pregnancy and in Inflammatory Bowel Diseases: A Prospective Study and Review of the Literature.
Fecal lactoferrin as a marker for disease activity in inflammatory bowel disease: comparison with other neutrophil-derived proteins.
Fecal lactoferrin as a noninvasive biomarker in inflammatory bowel diseases.
Fecal Lactoferrin for Assessment of Inflammatory Bowel Disease Activity: A Systematic Review and Meta-Analysis.
Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis.
Fecal lactoferrin in discriminating inflammatory bowel disease from Irritable bowel syndrome: a diagnostic meta-analysis.
Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation.
Fecal lactoferrin is a sensitive and specific marker of disease activity in children and young adults with inflammatory bowel disease.
Fecal lactoferrin predicts primary non-response to biologic agents in inflammatory bowel disease.
Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease.
Immune abnormalities and endotoxemia in patients with ulcerative colitis and in their first degree relatives: attempts at neutralizing endotoxin-mediated effects.
Impaired deoxyribonuclease I activity in patients with inflammatory bowel diseases.
Inflammatory bowel disease activity assessed by fecal calprotectin and lactoferrin: correlation with laboratory parameters, clinical, endoscopic and histological indexes.
Lactoferrin in gastrointestinal disease.
Lactoferrin in whole gut lavage fluid as a marker for disease activity in inflammatory bowel disease: comparison with other neutrophil-derived proteins.
Lactoferrin Induces Tolerogenic Bone Marrow-Derived Dendritic Cells.
Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
Lactoferrin: A Roadmap to the Borderland between Caries and Periodontal Disease.
Measurement of faecal calprotectin and lactoferrin in inflammatory bowel disease.
Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices.
Oral administration of lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
Prevalence and clinical significance of anti-lactoferrin autoantibodies in inflammatory bowel diseases and primary sclerosing cholangitis.
Prospective evaluation of faecal neutrophil-derived proteins in identifying intestinal inflammation: combination of parameters does not improve diagnostic accuracy of calprotectin.
Questions and answers on the role of fecal lactoferrin as a biological marker in inflammatory bowel disease.
Reference values of fecal calgranulin C (S100A12) in school aged children and adolescents.
Relationship between fecal lactoferrin and inflammatory bowel disease.
Relevance of fecal calprotectin and lactoferrin in the post-operative management of inflammatory bowel diseases.
Review article: biological activity markers in inflammatory bowel disease.
Technology insight: calprotectin, lactoferrin and nitric oxide as novel markers of inflammatory bowel disease.
The clinical value of faecal calprotectin and lactoferrin measurement in postoperative Crohn's disease.
The utility of C-reactive protein, erythrocyte sedimentation rate, fecal calprotectin and fecal lactoferrin to exclude inflammatory bowel disease in adults with IBS.
Timely Monitoring of Inflammation by Fecal Lactoferrin Rapidly Predicts Therapeutic Response in Inflammatory Bowel Disease.
Usefulness of ascitic fluid lactoferrin levels in patients with liver cirrhosis.
Utility of a rapid fecal latex agglutination test detecting the neutrophil protein, lactoferrin, for diagnosing inflammatory causes of chronic diarrhea.
VEN-120, a Recombinant Human Lactoferrin, Promotes a Regulatory T Cell [Treg] Phenotype and Drives Resolution of Inflammation in Distinct Murine Models of Inflammatory Bowel Disease.
[Noninvasive Markers in the Assessment of Intestinal Inflammation in Inflammatory Bowel Diseases: Performance of Fecal Lactoferrin, Calprotectin, PMN-Elastase, CRP, and Clinical Indices.]
[Utility of fecal markers of inflammation in the diagnostics of inflammatory bowel diseases]
Influenza, Human
Antiviral activities of whey proteins.
Assay for influenza virus endonuclease using DNA polymerase extension of a specific cleavage product.
Auditory Responses of Engrailed and Invected-Expressing Johnston's Organ Neurons in Drosophila melanogaster.
Bovine lactoferrin inhibits Influenza A virus induced programmed cell death in vitro.
Bovine Lactoferrin Prevents Influenza A Virus Infection by Interfering with the Fusogenic Function of Viral Hemagglutinin.
Bovine lactoferrin-derived peptides as novel broad-spectrum inhibitors of influenza virus.
Bovine lactoferrin: involvement of metal saturation and carbohydrates in the inhibition of influenza virus infection (1) (1) This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process.
Cognate peptide-receptor ligand mapping by directed phage display.
Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations.
Diagnostic value of blood cytokine concentrations in acute pneumonia.
Effects of orally administered bovine lactoferrin and lactoperoxidase on influenza virus infection in mice.
Effects of ribonuclease and deoxyribonuclease on a murine leukemia virus (Rauscher).
Evaluation of PCR assays in presence of antibody to thermostable DNA polymerases for detection of microbial agents: avoiding false negative results for specimen containing low-titer agent.
Exacerbation of bacterial toxicity to infant ferrets by influenza virus: possible role in sudden infant death syndrome.
Function, structure and regulation of the vacuolar (H+)-ATPases.
Gateways to clinical trials.
Haploid genetic screens in human cells identify host factors used by pathogens.
Highlights in the development of new antiviral agents.
Influenza virus enhancement of membrane leakiness induced by staphylococcal alpha toxin, diphtheria toxin and streptolysin S.
Inhibition by kappa-casein glycomacropeptide and lactoferrin of influenza virus hemagglutination.
Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide.
Lactoferrin acts as an adjuvant during influenza vaccination of neonatal mice.
Lactoferrin for prevention of common viral infections.
Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors.
Optimized PCR amplification of influenza A virus RNA using Tth DNA polymerase, incorporating uracil N glycosylase (UNG) in a single tube reaction.
RNA and DNA hydrolysis are catalyzed by the influenza virus endonuclease.
Structure, dynamics and function of the outer membrane protein A (OmpA) and influenza hemagglutinin fusion domain in detergent micelles by solution NMR.
The Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses.
The PentaFOLD 3.0 algorithm for the selection of stable elements of secondary structure to be included in vaccine peptides.
Insulin Resistance
Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance.
Cardiometabolic risk factors and lactoferrin: Polymorphisms and plasma levels in french canadian children.
Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes.
Plasma Lactoferrin Levels Positively Correlate with Insulin Resistance despite an Inverse Association with Total Adiposity in Lean and Severely Obese Patients.
Proadipogenic effects of lactoferrin in human subcutaneous and visceral preadipocytes.
Insulinoma
Liver-specific enhancer of the glucokinase gene.
Intellectual Disability
Defective DNA Polymerase ?-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism.
Tissue-specific DNase I footprint analysis confirms the association of GATAD2B Q470* variant with intellectual disability.
Intervertebral Disc Displacement
Anti-nociceptive effect of bovine milk-derived lactoferrin in a rat lumbar disc herniation model.
Intestinal Diseases
Fecal lactoferrin as a noninvasive biomarker in inflammatory bowel diseases.
Lactoferrin protects rabbits from Shigella flexneri-induced inflammatory enteritis.
Monoclonal antibody testing for fecal calprotectin is superior to polyclonal testing of fecal calprotectin and lactoferrin to identify organic intestinal disease in patients with abdominal discomfort.
Questions and answers on the role of fecal lactoferrin as a biological marker in inflammatory bowel disease.
[Biological properties of opportunistic microorganisms isolated from patients with acute intestinal diseases]
Intestinal Polyposis
Inhibitory effects of bovine lactoferrin on intestinal polyposis in the Apc(Min) mouse.
Intestinal Volvulus
Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats.
Intracranial Hemorrhages
Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke.
Invasive Fungal Infections
Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial.
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
NEW POSSIBILITIES OF PREVENTION OF INFECTION IN THE NEWBORN.
Iridocyclitis
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Mycobacterium leprae infection and serum lactoferrin levels.
Iron Deficiencies
Lactoferrin efficacy versus ferrous sulfate in curing iron deficiency and iron deficiency anemia in pregnant women.
Lactoferrin, a bird's eye view.
Recombinant human lactoferrin treatment for global health issues: iron deficiency and acute diarrhea.
Safety and efficacy of lactoferrin versus ferrous sulphate in curing iron deficiency and iron deficiency anaemia in hereditary thrombophilia pregnant women: an interventional study.
The Fur iron regulator-like protein is cryptic in the hyperthermophilic archaeon Thermococcus kodakaraensis.
The influence of lactoferrin, orally administered, on systemic iron homeostasis in pregnant women suffering of iron deficiency and iron deficiency anaemia.
[Activity of oral lactoferrin into systematic iron homeostasis in pregnant women suffering from iron deficiency and iron deficiency anemia].
Iron Metabolism Disorders
The treatment of black stain associated with of iron metabolism disorders with lactoferrin: a litterature search and two case studies.
Iron Overload
Are extrinsic black stains of teeth iron-saturated bovine lactoferrin and a sign of iron deficient anemia or iron overload?
Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis.
Lactoferrin and oral diseases: current status and perspective in periodontitis.
Lactoferrin in human neutrophilic polymorphonuclear leukocytes in relation to iron metabolism.
Irritable Bowel Syndrome
Diagnostic performance of rapid tests for detection of fecal calprotectin and lactoferrin and their ability to discriminate inflammatory from irritable bowel syndrome.
Faecal lactoferrin, capsule endoscopy and Crohn's disease. Is there a three way relationship? A pilot study.
Fecal lactoferrin in discriminating inflammatory bowel disease from Irritable bowel syndrome: a diagnostic meta-analysis.
Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation.
Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices.
Prospective evaluation of faecal neutrophil-derived proteins in identifying intestinal inflammation: combination of parameters does not improve diagnostic accuracy of calprotectin.
Utility of fecal lactoferrin in identifying Crohn disease activity in children.
Ischemic Stroke
Erythrocyte damage and leukocyte activation in ischemic stroke.
Neutrophil extracellular traps in ischemic stroke thrombi.
Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke.
Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance.
Joint Diseases
Eosinophil cationic protein in inflammatory synovial effusions as evidence of eosinophil involvement.
What is the performance of novel synovial biomarkers for detecting periprosthetic joint infection in the presence of inflammatory joint disease?
Keratitis
A Dual Role for Corneal Dendritic Cells in Herpes Simplex Keratitis: Local Suppression of Corneal Damage and Promotion of Systemic Viral Dissemination.
Chemotherapy of herpetic keratitis induced by acyclovir-resistant strains of herpes simplex virus type 1.
Effect of trisodium phosphonoformate and idoxuridine on experimental herpes simplex keratitis in immunized and non-immunized rabbits.
Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis.
Lactoferrin protects against UV-B irradiation-induced corneal epithelial damage in rats.
Quantification of lacrimal function after D-shaped field irradiation for retinoblastoma.
Keratitis, Herpetic
Evaluation of tear samples for Herpes Simplex Virus 1 (HSV) detection in suspected cases of viral keratitis using PCR assay and conventional laboratory diagnostic tools.
Lactoferrin Glu561Asp polymorphism is associated with susceptibility to herpes simplex keratitis.
[Comparative effectiveness of gamma-globulin, deoxyribonuclease and kerecid in herpetic keratitis]
[Comparative evaluation of the effectiveness of synthetis 2-thread polyribonucleotide complex and desoxyribonuclease in the treatment of experimental herpetic keratitis]
Keratoconjunctivitis
Conjunctival Injection Reduction in Patients with Atopic Keratoconjunctivitis Due to Synergic Effect of Bovine Enteric-Coated Lactoferrin in 0.1% Tacrolimus Ophthalmic Suspension.
Modifying Effect of Colicin on Experimental Shigella Keratoconjunctivitis.
[The use of desoxyribonuclease in the therapy of adenovirus epidemic keratoconjunctivitis]
Keratoconjunctivitis Sicca
A simple test for lacrimal gland function: a tear lactoferrin assay by radial immunodiffusion.
Diagnostic tests in patients with symptoms of keratoconjunctivitis sicca.
Ocular surface damage and tear lactoferrin in dry eye syndrome.
Rapid assay of lactoferrin in keratoconjunctivitis sicca.
Salivary lactoferrin in primary Sjögren's syndrome.
Tear fluid proteins in Sjögren's syndrome.
Tear function parameters in keratoconjunctivitis sicca with and without the association of Sjögren's syndrome.
Tear lipocalin and lysozyme in Sjögren and non-Sjögren dry eye.
The diagnostic power of the tests for tear gland related keratoconjunctivitis sicca.
The lactoferrin tear test in the diagnosis of Sjögren's syndrome.
The lactoferrin test for the diagnosis of keratoconjunctivitis sicca in clinical practice.
[Tear lactoferrin content in normal Chinese adults and various ocular diseases]
[Tear lactoferrin in keratoconjunctivitis sicca]
Keratoconus
Lactoferrin-loaded contact lenses counteract cytotoxicity caused in vitro by keratoconic tears.
Levels of lactoferrin, secretory IgA and serum albumin in the tear film of people with keratoconus.
Tear Lipocalin and Lipocalin-Interacting Membrane Receptor.
Keratosis, Actinic
E6/E7 expression of human papillomavirus types in cutaneous squamous cell dysplasia and carcinoma in immunosuppressed organ transplant recipients.
Kidney Failure, Chronic
Deoxyribonuclease activity in lymphocytes of patients with chronic renal failure treated conservatively.
Deoxyribonuclease activity in T and B lymphocytes of haemodialysed patients with uraemia.
Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis.
[Determination of lactoferrin in the diagnosis of pancreatopathy in patients with chronic kidney failure]
Laryngeal Diseases
[Content of protein lactoferrin in precancer laryngeal disease]
Laryngitis
Dornase alfa. A review of its pharmacological properties and therapeutic potential in cystic fibrosis.
[Content of protein lactoferrin in precancer laryngeal disease]
Latent Infection
Lactoferrin inhibits early steps of human BK polyomavirus infection.
Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase.
The Epstein-Barr virus (EBV) BMRF1 promoter for early antigen (EA-D) is regulated by the EBV transactivators, BRLF1 and BZLF1, in a cell-specific manner.
The Ozobranchus leech is a candidate mechanical vector for the fibropapilloma-associated turtle herpesvirus found latently infecting skin tumors on Hawaiian green turtles (Chelonia mydas).
[Antidesoxyribonuclease B-titer in persons of different ages and sex and comparative studies of antistreptolysin titers]
Leg Ulcer
Comparison of saline and streptokinase-streptodornase in the treatment of leg ulcers.
Leishmaniasis
Leishmania chagasi: uptake of iron bound to lactoferrin or transferrin requires an iron reductase.
Natural infection of North African gundi (Ctenodactylus gundi) by Leishmania tropica in the focus of cutaneous leishmaniasis, Southeast Tunisia.
Structures of the Leishmania infantum polymerase beta.
Leishmaniasis, Cutaneous
Leishmania (Viannia) infection in the domestic dog in Chaparral, Colombia.
Natural infection of North African gundi (Ctenodactylus gundi) by Leishmania tropica in the focus of cutaneous leishmaniasis, Southeast Tunisia.
Leishmaniasis, Visceral
Polarized M2 macrophages in dogs with visceral leishmaniasis.
Leprosy
Elevated free tear lactoferrin levels in leprosy are associated with Type 2 reactions.
Immunohistochemical identification of ferritin, lactoferrin and transferrin in leprosy lesions of human skin biopsies.
Mycobacteria and human autoimmune disease: direct evidence of cross-reactivity between human lactoferrin and the 65-kilodalton protein of tubercle and leprosy bacilli.
Mycobacterium leprae infection and serum lactoferrin levels.
Leprosy, Lepromatous
Serum lactoferrin in lepromatous leprosy patients.
Leukemia
A diphtheria toxin interleukin-3 fusion protein synergizes with tyrosine kinase inhibitors in killing leukemic progenitors from BCR/ABL positive acute leukemia.
A milk protein lactoferrin enhances human T cell leukemia virus type I and suppresses HIV-1 infection.
A novel mechanism for inhibition of HIV-1 reverse transcriptase.
Activation of DNA polymerase of murine leukemia virus by rifamycin derivatives.
Active genes are sensitive to deoxyribonuclease I during metaphase.
An aptamer biosensor for leukemia marker mRNA detection based on polymerase-assisted signal amplification and aggregation of illuminator.
An enhancer element lies 3' to the human A gamma globin gene.
An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region.
Analysis of the early and late products of the DNA polymerase of friend murine leukemia virus with actinomycin D.
Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions.
Anti-leukemia effect of resveratrol.
Antigens in chromatin associated with proliferating and nonproliferating cells.
Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.
Automated Extraction of DNA and RNA from a Single Formalin-Fixed Paraffin-Embedded Tissue Section for Analysis of Both Single-Nucleotide Polymorphisms and mRNA Expression.
Bacteriocin and flow cytometry in laboratory diagnosis of leukemic peripheral blood lymphocytes and bone marrow cells.
Binding characteristics of human lactoferrin to the human monocytic leukemia cell line THP-1 differentiated into macrophages.
Biochemical and immunological characterization of Suncus murinus mammary tumor virus DNA polymerase.
Biologic activities of poly (2-azaadenylic acid) and poly (2-azainosinic acid).
Characterization of an RNA-directed DNA-polymerase from a cell line derived from a radiation-induced lymphoma in mice.
Characterization of lactoferrin-binding proteins of human macrophage membrane: multiple species of lactoferrin-binding proteins with polylactosamine-binding ability.
Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases.
Comparison of plasma deoxyribonuclease activity between normal and leukemic states in man and mice.
Comparison of two methods of staining apoptotic cells of leukemia cell lines. Terminal deoxynucleotidyl transferase and DNA polymerase I reactions.
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection.
Decreased Km to dNTPs is an essential M-MuLV reverse transcriptase adoption required to perform efficient cDNA synthesis in One-Step RT-PCR assay.
Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H.
Detection of exon polymorphisms in the human lactoferrin gene.
Detection of reverse transcriptase activity in human cells.
Development of a one tube-one step RT-PCR protocol for the detection of seven viroids in four genera: Apscaviroid, Hostuviroid, Pelamoviroid and Pospiviroid.
Development of an efficient one-step real-time reverse transcription polymerase chain reaction method for severe acute respiratory syndrome-coronavirus-2 detection.
Differential effect of collaterally sensitive antimetabolites on P388 murine leukemia sensitive and resistant to adriamycin in vitro.
Differential inhibition of DNA polymerase and RNase H activities of the reverse transcriptase by phosphonoformate.
Dimethyladenosine dialdehyde: inhibition of leukemia 1210 DNA polymerase.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor and Ara-C exert synergistic toxicity against human AML HL-60 cells.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias.
Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.
Dissociation of alpha beta DNA polymerase of avian myeloblastosis virus by dimethyl sulfoxide.
Divalent cation-dependent pyridoxal 5'-phosphate inhibition of Rauscher leukemia virus DNA polymerase: characterization and mechanism of action.
DNA binding and topoisomerase I poisoning activities of novel disaccharide indolocarbazoles.
DNA polymerase from Gross murine leukemia.
DNAase I digestion of early, middle, and late S phase replicating DNA in murine leukemia L5178Y cells.
DNase I sensitivity of immunoglobulin light chain genes in Abelson murine leukemia virus transformed pre-B cell lines.
Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities.
Drug-induced changes in the expression of MDR-associated genes: investigations on cultured cell lines and chemotherapeutically treated leukemias.
EFFECT OF ADMINISTRATION OF ALKYLATING AGENTS OR 6-MERCAPTOPURINE ON SERUM LEVEL OF DEOXYRIBONUCLEASE I IN LEUKEMIA PATIENTS.
Effect of colicin E3 on leukemia cells P388 in vitro.
Effect of pH on the base-mispairing properties of 5-bromouracil during DNA synthesis.
Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities.
Effects of exogenous polyamine and trypanocides on the DNA polymerase activities from Trypanosoma brucei brucei, mouse thymus and murine leukemia virus.
Effects of ribonuclease and deoxyribonuclease on a murine leukemia virus (Rauscher).
Effects of streptovaricins and their degradation products on RNA-directed DNA polymerase of Rauscher leukemia virus.
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.
Enhanced detection of RNA by MMLV reverse transcriptase coupled with thermostable DNA polymerase and DNA/RNA helicase.
Enhancement of cellular protein synthesis sensitivity to diphtheria toxin by interferon.
Estimation of numbers of mature and immature neutrophils in blood by a novel, rapid and simple technology.
Evidence for the presence of DNase-actin complex in L1210 leukemia cells.
Exonucleolytic proofreading by p53 protein.
Expression of enzymatically active reverse transcriptase of simian immunodeficiency virus in bacteria: sensitivity to nucleotide analogue inhibitors.
Expression of murine leukemia virus DNA polymerase in mouse uterus during pregnancy.
Ferrate oxidation of murine leukemia virus reverse transcriptase: identification of the template-primer binding domain.
Flow cytometric analysis of intracellular myeloperoxidase and lactoferrin in leukemia diagnosis.
Flow cytometric detection of proliferative cells in leukemias.
Functional organization of the murine leukemia virus reverse transcriptase: characterization of a bacterially expressed AKR DNA polymerase deficient in RNase H activity.
Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.
GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF.
Hamster leukemia virus: lack of endogenous DNA synthesis and unique structure of its DNA polymerase.
Heterogeneous pathways of oxidizing radical production in human neutrophils and the HL-60 cell line.
Homebrew reagents for low cost RT-LAMP.
Immunocytochemical identification of abnormal polymorphonuclear neutrophils in patients with leukemia.
Immunoradiometric assay of plasma lactoferrin.
Immunotoxins in cancer therapy: Review and update.
In vivo targeting of leukemic cells using diphtheria toxin fused to murine GM-CSF.
Influence of DNA sequence on the nature of mispairing during DNA synthesis.
Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir.
Inhibition of DNA polymerase by sera of patients having leukemia and other reticuloendothelial malignancies.
Inhibition of DNA polymerase from L1210 murine leukemia by a sulfhydryl reagent from agaricus bisporus.
Inhibition of oncornavirus functions by poly (2-methylthioinosinic acid).
Inhibition of RNA directed DNA polymerase of murine leukemia virus by 2'-O-alkylated polyadenylic acids.
Inhibition of the DNA polymerase of Rauscher leukemia virus by single-stranded polyribonucleotides.
Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.
Interconversion of molecular size of DNA polymerase from Rauscher leukemia virus.
Interconversion of molecular size of the DNA polymerase from Rauscher leukemia virus.
Intracellular markers in acute myeloid leukemia diagnosis.
Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene.
Isolation of lactoferrin cDNA from a human myeloid library and expression of mRNA during normal and leukemic myelopoiesis.
Lactoferrin binding by leukemia cell lines.
Lactoferrin biosynthesis during granulocytopoiesis.
Lactoferrin gene promoter: structural integrity and nonexpression in HL60 cells.
Lactoferrin, transferrin and acidic isoferritins: regulatory molecules with potential therapeutic value in leukemia.
Lysine-329 of murine leukemia virus reverse transcriptase: possible involvement in the template-primer binding function.
Mechanism of action of Moloney murine leukemia virus RNA-directed DNA polymerase associated RNase H (RNase H I).
Mechanism of inhibition of HIV reverse transcriptase by toxiusol, a novel general inhibitor of retroviral and cellular DNA polymerases.
Metabolism of 5-fluorouracil in sensitive and resistant tumor cells.
Methylation state and DNase I sensitivity of chromatin containing Moloney murine leukemia virus DNA in exogenously infected mouse cells.
Molecular mimicry between a uveitopathogenic site of S-antigen and viral peptides. Induction of experimental autoimmune uveitis in Lewis rats.
Moloney murine leukemia virus-induced tumors: recombinant proviruses in active chromatin regions.
Mutational analysis of the ribonuclease H activity of human immunodeficiency virus 1 reverse transcriptase.
Next-generation sequencing-based analysis of reverse transcriptase fidelity.
One-Enzyme Reverse Transcription qPCR Using Taq DNA Polymerase.
Optimization of a synthetic beta-catenin-dependent promoter for tumor-specific cancer gene therapy.
Overall changes in chromatin sensitivity to DNase I during differentiation.
p53-associated 3'-->5' exonuclease activity in nuclear and cytoplasmic compartments of cells.
Persistent deficiency of myeloperoxidase and lactoferrin in granulopoietic cells of patients with acute leukemia.
PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells.
Physical characteristics and polymerization during iron saturation of lactoferrin, a myelopoietic regulatory molecule with suppressor activity.
Polyamines antagonize both the antileukemic activity and the reverse transcriptase stimulatory activity of 4,4'-diacetyldiphenylurea bis(guanylhydrazone) (DDUG).
Polyamines stimulate DNA-directed DNA synthesis catalyzed by mammalian type C retroviral DNA polymerases.
Polyamines stimulate natural RNA-directed DNA synthesis by Rauscher murine leukemia virus DNA polymerase.
Polymorphism and altered methylation of the lactoferrin gene in normal leukocytes, leukemic cells, and breast cancer.
Polynucleotides containing 5-mercapto-substituted pyrimidines: inhibition of viral DNA polymerases and the biological implication.
Potential role of oxidative stress-induced apoptosis in mediating chromosomal rearrangements in nasopharyngeal carcinoma.
Purification and characterization of gibbon ape leukemia virus DNA polymerase.
Purification and properties of Rauscher leukemia virus DNA polymerase and selective inhibition of mammalian viral reverse transcriptase by inorganic phosphate.
Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes.
Rapid amplification of complementary DNA from small amounts of unfractionated RNA.
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies.
Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Recurrence of hepatitis B in children with serologic evidence of past hepatitis B virus infection undergoing antileukemic chemotherapy.
RNA directed DNA polymerase in C-type particles form normal rat thymus cultures and Moloney leukemia virus.
RNA-dependent DNA polymerase activity in cauliflower mosaic virus-infected plant leaves.
Specific antigenic relationships between the RNA-dependent DNA polymerases of avian reticuloendotheliosis viruses and mammalian type C retroviruses.
Specific inhibition of DNA polymerase-associated RNase H by DNA.
Specific inhibitory activity against granulocyte-progenitor cells produced by non-T lymphocytes from patients with neutropenia.
Specificities involved in the initiation of retroviral plus-strand DNA.
Spontaneous production of a C-type RNA virus in a cell line derived from rat glioma.
Stimulation of Rauscher leukemia virus DNA polymerase DNA-directed DNA synthesis by cationic trypanocides and polyamines.
Structure of products of the Moloney murine leukemia virus endogenous DNA polymerase reaction.
Structure-activity relationships in HIV-1 reverse transcriptase revealed by radiation target analysis.
Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H.
Synthesis of murine leukemia virus proteins associated with virions assembled in actinomycin D-treated cells: evidence for persistence of viral messenger RNA.
Terminal deoxynucleotidyl transferase and human leukemia.
The 30S Moloney sarcoma virus RNA contains leukemia virus nucleotide sequences.
The biochemical status of the DNA synthesome can distinguish between permanent and temporary cell growth arrest.
The BRCA-1 binding protein BRAP2 is a novel, negative regulator of nuclear import of viral proteins, dependent on phosphorylation flanking the nuclear localization signal.
The isolation of a DNA synthesome from human leukemia cells.
The mechanism of inorganic phosphate-mediated inhibition of calf thymus DNA polymerase beta and Rauscher leukemia virus dna polymerase.
The nucleotides at the RNA-DNA joint formed by the DNA polymerase of Rauscher leukemia virus.
The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells.
Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.
Two serologic markers to monitor the engraftment, growth, and treatment response of human leukemias in severe combined immunodeficient mice.
Two simple high-performance liquid chromatographic methods for simultaneous determination of 2'-deoxycytidine 5'-triphosphate and cytosine arabinoside 5'-triphosphate concentrations in biological samples.
Variations in serum alkaline DNase activity: a new means to assess early detection of relapse in patients treated for acute nonlymphoblastic leukemia.
Varied Molecular Interactions at the Active Sites of Several DNA Polymerases: Nonpolar Nucleoside Isosteres as Probes.
[Cytochemical identification of acid deoxyribonuclease in blood cell cytoplasm. 3. Activity of acid deoxyribonuclease in leukocyte cytoplasm of children suffering from acute leukemia]
[Detection of proliferative cells by DNA polymerase a as a proliferation associated marker]
[Diphtheria toxin: ability to agglutinate human leukemia cells]
[Increases in the activity of lysosomal DNAase in mouse liver during the development of Friend's viral leukemia]
[Lysosomal hydrolase activity during development of experimental leukemia]
[On the effect of desoxyribonuclease on the development of spontaneous leukemia in mice of the AKR line]
[Possible role of DNAse I in the development of experimental leukemia]
[The effect of deoxyribonuclease on the course of spontaneous lympholeukosis in mice from the high leukemia line AKR]
Leukemia L1210
Separation and properties of DNA polymerase from murine leukemia L1210 cells.
Leukemia, Erythroblastic, Acute
A procedure to introduce protein molecules into living mammalian cells.
Affinity isolation of active murine erythroleukemia cell chromatin: uniform distribution of ubiquitinated histone H2A between active and inactive fractions.
Affinity isolation of transcriptionally active murine erythroleukemia cell DNA using a cleavable biotinylated nucleotide analog.
Alterations in globin gene chromatin conformation during murine erythroleukemia cell differentiation.
An enhancer element lies 3' to the human A gamma globin gene.
Cross-linking of proteins in nuclei and DNA-depleted nuclei from Friend erythroleukemia cells.
Differences of globin transgene expression in stably transfected cell lines and transgenic mice.
DNA polymerase activities during induced differentiation in murine erythroleukemia cells.
DNAase I nuclease digestion studies of the human zeta globin gene before and after transfer from the K562 cell to the mouse erythroleukemia cell.
DNase I hypersensitive sites of globin genes of uninduced Friend erythroleukemia cells and changes during induction with dimethyl sulfoxide.
DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial cells.
Effects of purified iron-saturated human lactoferrin on spleen morphology in mice infected with Friend virus complex.
Evidence that the transcription factor USF is a component of the human beta-globin locus control region heteromeric protein complex.
Functional analysis of DNase-I hypersensitive sites at the mouse porphobilinogen deaminase gene locus. Different requirements for position-independent expression from its two promoters.
High pressure sensitizes murine erythroleukemia cells to caffeine-induced premature mitosis.
Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice.
Isolation from Friend erythroleukemia cells of an RNase-sensitive nuclear matrix fibril fraction containing hnRNA and snRNA.
Localization of DNA methyltransferase in the chromatin of Friend erythroleukemia cells.
Murine erythroleukemia cell differentiation: DNase I hypersensitivity and DNA methylation near the globin genes.
Overexpression of c-Myc inhibits the appearance of a specific DNase I hypersensitive site in the beta-globin chromatin in murine erythroleukemia cells.
Overexpression of initiation factor eIF-4E does not relieve the translational repression of ribosomal protein mRNAs in quiescent cells.
Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.
Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines. Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization.
Leukemia, Experimental
[Possible role of DNAse I in the development of experimental leukemia]
Leukemia, Feline
Biochemical and immunological properties of the DNA polymerase and RNAase H activities of purified feline leukemia virus reverse transcriptase.
Multiple RNase H activities in mammalian type C retravirus lysates.
Leukemia, Hairy Cell
Immunotoxins in cancer therapy: Review and update.
Leukemia, Lymphocytic, Chronic, B-Cell
Bacteriocin and flow cytometry in laboratory diagnosis of leukemic peripheral blood lymphocytes and bone marrow cells.
DNA polymerase ? gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently from p53 status.
Immunotoxins in cancer therapy: Review and update.
Phase II clinical studies of denileukin diftitox diphtheria toxin fusion protein in patients with previously treated chronic lymphocytic leukemia.
Radioimmunometric quantification of surface lactoferrin in blood mononuclear cells.
[The role of deoxyribonuclease in the treatment of chronic lymphocytic leukemia]
Leukemia, Lymphoid
Antitumor agents. XXXIV: Mechanism of action of bruceoside A and brusatol on nucleic acid metabolism of P-388 lymphocytic leukemia cells.
Detection of low abundance mRNA of myeloid specific genes in cells of acute and chronic lymphoid leukemias by cRNA hybridization.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Biosynthesis and processing of lactoferrin in bone marrow cells, a comparison with processing of myeloperoxidase.
Effects of nitrosoureas on human DNA polymerase activities from acute and chronic granulocytic leukemia cells.
Interferon-alpha directly inhibits DNA polymerase activity in isolated chromatin nucleoprotein complexes: correlation with IFN-alpha treatment outcome in patients with chronic myelogenous leukemia.
Isolation of lactoferrin cDNA from a human myeloid library and expression of mRNA during normal and leukemic myelopoiesis.
Lactoferrin biosynthesis during granulocytopoiesis.
Lactoferrin gene promoter: structural integrity and nonexpression in HL60 cells.
Long-template DNA polymerase chain reaction for the detection of the bcr/abl translocation in patients with chronic myelogenous leukemia.
Qualitative functional deficiency of affinity-purified lactoferrin from neutrophils of patients with chronic myelogenous leukemia, and lactoferrin/H-ferritin-cell interactions in a patient with lactoferrin-deficiency with normal numbers of circulating leukocytes.
Leukemia, Myeloid
Clinical studies of new "biologic" approaches to therapy of acute myeloid leukemia with monoclonal antibodies and immunoconjugates.
Comparison of the apoptosis-inducing abilities of various protein synthesis inhibitors in U937 cells.
Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias.
In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor.
L, D-Polydeoxyribonucleotides to provide an essential inhibitory effect on DNA polymerase ? of human myeloid leukemia HL60 cells.
Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
Multiple forms of lactoferrin in normal and leukemic human granulocytes.
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies.
Leukemia, Myeloid, Acute
A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts.
Antibacterial prophylaxis with lactoferrin in neutropenic patients.
Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.
Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.
Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein.
Detection of terminal transferase in acute myeloid leukemia by flow cytometry.
Diagnostic and prognostic significance of serum measurements of lactoferrin, lysozyme and myeloperoxidase in acute myeloid leukemia (AML): recognition of a new variant, high-lactoferrin AML.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of blasts from patients with acute myeloid leukemia according to the level of interleukin-3 receptor expression.
Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice.
Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor-induced hepatotoxicity is mediated by Kupffer cells.
DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.
Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice.
Expression of PKC isozyme and MDR-associated genes in primary and relapsed state AML.
Expression of terminal deoxynucleotidyl transferase (TdT) in classical seminoma: a potential diagnostic pitfall.
Immunotoxins in cancer therapy: Review and update.
L, D-Polydeoxyribonucleotides to provide an essential inhibitory effect on DNA polymerase ? of human myeloid leukemia HL60 cells.
Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia.
Reactivity with TdT in Merkel cell carcinoma: a potential diagnostic pitfall.
Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey.
TdT expression in Merkel cell carcinoma: potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis.
Terminal deoxynucleotidyl transferase (TdT) expression is associated with FLT3-ITD mutations in Acute Myeloid Leukemia.
The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34+CD123+ cells from acute myeloid leukemia/myelodysplastic syndrome patients and healthy donors.
The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity.
Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.
Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys.
Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells.
Variant Diphtheria Toxin-Interleukin-3 Fusion Proteins with Increased Receptor Affinity Have Enhanced Cytotoxicity against Acute Myeloid Leukemia Progenitors.
Variations in serum alkaline DNase activity: a new means to assess early detection of relapse in patients treated for acute nonlymphoblastic leukemia.
Leukemia, Myelomonocytic, Chronic
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Leukemia, Myelomonocytic, Juvenile
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Leukemia, T-Cell
A milk protein lactoferrin enhances human T cell leukemia virus type I and suppresses HIV-1 infection.
Human T-cell leukemia virus types I and II exhibit different DNase I protection patterns.
Induction of lactoferrin gene expression in myeloid or mammary gland cells by human T-cell leukemia virus type 1 (HTLV-1) tax: implications for milk-borne transmission of HTLV-1.
Leukemia-Lymphoma, Adult T-Cell
Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.
Immunotoxins in cancer therapy: Review and update.
Leukocytosis
Association of antioxidants and natural immune activators in the treatment of asthenoteratospermia and abacterial leukocytosis.
Leukomalacia, Periventricular
Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
Leukopenia
Inhibition of endotoxin-induced cytokine release and neutrophil activation in humans by use of recombinant bactericidal/permeability-increasing protein.
[Deoxyribonuclease activity in the blood serum of persons participating in liquidation of the effects of the accident at the Chernobyl nuclear power plant]
Leukoplakia
[Content of protein lactoferrin in precancer laryngeal disease]
Leukoplakia, Oral
Serum alkaline deoxyribonuclease in oral cancer and premalignant lesions.
Li-Fraumeni Syndrome
Faulty DNA polymerase delta/epsilon-mediated excision repair in response to gamma radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome.
Lichen Planus
[Experience in using deoxyribonuclease in treating lichen ruber planus]
Lipidoses
Whey Protein Components - Lactalbumin and Lactoferrin - Improve Energy Balance and Metabolism.
Lipodystrophy
Functional analysis of POLD1 p.ser605del variant: the aging phenotype of MDPL syndrome is associated with an impaired DNA repair capacity.
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.
Liposarcoma
The low density lipoprotein receptor-related protein contributes to selective uptake of high density lipoprotein cholesteryl esters by SW872 liposarcoma cells and primary human adipocytes.
Liver Abscess, Amebic
Effect of bovine lactoferrin in a therapeutic hamster model of hepatic amoebiasis (1) (1) This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process.
Liver Cirrhosis
Heat shock protein 47 as indispensible participant in liver fibrosis: Possible protective effect of lactoferrin.
Lactoferrin Enhanced Apoptosis and Protected Against Thioacetamide-Induced Liver Fibrosis in Rats.
Lactoferrin protects against chemical-induced rat liver fibrosis by inhibiting stellate cell activation.
Usefulness of ascitic fluid lactoferrin levels in patients with liver cirrhosis.
Liver Cirrhosis, Biliary
Sialochemical markers of salivary gland involvement with Sjögren's syndrome secondary to rheumatoid arthritis and primary biliary cirrhosis.
Liver Diseases
Anti-neutrophil cytoplasmic antibodies (ANCA) in autoimmune liver disease.
Antilactoferrin antibodies in autoimmune liver diseases.
Association of DNase I phenotype 2 with colorectal carcinoma risk in Japanese populations.
Autoantibodies in autoimmune liver disease.
Bovine lactoferrin potently inhibits liver mitochondrial 8-OHdG levels and retrieves hepatic OGG1 activities in Long-Evans Cinnamon rats.
Dane particle DNA polymerase and HBeAg: impact on clinical, laboratory, and histologic findings in hepatitis B-associated chronic liver disease.
Detection of antibodies against DNA polymerase of hepatitis B virus in HBsAg-positive sera using ELISA.
Effect of human fibroblast interferon (INF-beta) on hepatitis B virus DNA in serum.
Extremely high prevalence of DNASE1*1 allele in African populations.
HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine.
Hepatitis B virus DNA polymerase activity and hepatitis B e antigen (HBeAg)/anti-HBe status among type B chronic liver diseases.
Hepatitis B virus genomes of chronic hepatitis patients do not contain specific mutations related to acute exacerbation.
Immunohistochemical evidence of lactoferrin in hepatic biopsies of patients with viral or cryptogenetic chronic liver disease.
Prevalence and characterization of neutrophil cytoplasmic antibodies in autoimmune liver diseases.
Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice.
Survey of the association of deoxyribonuclease I polymorphism with disease.
Survival in chronic hepatitis B. An analysis of 379 patients.
[Changes in HBV-specific DNA polymerase activity in relation to the severity of HBsAg positive chronic liver disease]
[Inhibition of hepatitis B virus associated DNA polymerase by antiviral agents: in vitro studies with clinical implications (author's transl)]
Liver Diseases, Alcoholic
Prevalence and heterogeneity of serum DNA polymerase activity in patients with non-A, non-B hepatitis and HBsAg-negative blood donors with elevated SGPT.
Liver Failure
Bovine lactoferrin potently inhibits liver mitochondrial 8-OHdG levels and retrieves hepatic OGG1 activities in Long-Evans Cinnamon rats.
Deoxyribonuclease partially ameliorates thioacetamide-induced hepatorenal injury.
Mutation of the core region of HBV-DNA and submassive hepatic necrosis in patients with anti-HBe-positive chronic hepatitis B.
Liver Failure, Acute
Generation of a Humanized Mouse Liver Using Human Hepatic Stem Cells.
Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities.
Liver Neoplasms
Cancer-selective induction of cytotoxicity by tissue-specific expression of targeted trans-splicing ribozyme.
Deoxyribonuclease I Activity, Cell-Free DNA, and Risk of Liver Cancer in a Prospective Cohort.
Expression of IL-13Ralpha2 in liver cancer cells and its effect on targeted therapy of liver cancer.
Hepatocellular carcinoma targeting effect of PEGylated liposomes modified with lactoferrin.
Stability analysis of liver cancer-related microRNAs.
[A study on the desoxyribonuclease activity of Yoshida ascites liver cancer.]
[A study on the desoxyribonuclease activity of Yoshida ascitic liver cancer.]
Liver Neoplasms, Experimental
A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex.
Deoxyribonucleic acid dependent adenosinetriphosphatases from the Novikoff hepatoma. Characterization of a homogeneous adenosinetriphosphatase that stimulates DNA polymerase beta.
Hepatoma-associated nonhistone chromosomal proteins are present in active chromatin.
Preribosomal ribonucleoprotein particles are a major component of a nucleolar matrix fraction.
Stimulation of DNA polymerase by factors isolated from Novikoff hepatoma.
Lung Abscess
The use of parenterally administered pancreatic desoxyribonuclease as an adjunct in the treatment of pulmonary abscesses.
Lung Diseases
Actin-Resistant DNase1L2 as a Potential Therapeutics for CF Lung Disease.
Aerosolized dornase alfa (rhDNase) for therapy of cystic fibrosis.
Aerosolized dornase alfa in cystic fibrosis: is there a role in the management of patients with early obstructive lung disease?
Deoxyribonuclease for cystic fibrosis.
DNA concentrations in BAL fluid of cystic fibrosis patients with early lung disease: influence of treatment with dornase alpha.
Does the timing of inhaled dornase alfa matter?
Dornase alfa (Pulmozyme).
Dornase alfa for cystic fibrosis.
Dornase alfa in early cystic fibrosis lung disease.
Dornase alfa reduces air trapping in children with mild cystic fibrosis lung disease: a quantitative analysis.
Dornase alfa. A review of its pharmacological properties and therapeutic potential in cystic fibrosis.
Effect of dornase alfa on inflammation and lung function: Potential role in the early treatment of cystic fibrosis.
Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis. Dornase Alfa Nebulizer Group.
Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease. Pulmozyme Study Group.
Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
Epidemiologic Study of Cystic Fibrosis: 25 years of observational research.
Factors associated with severe lung disease in an adult population with cystic fibrosis: a single center experience.
Improving evidence-based care in cystic fibrosis through quality improvement.
Lactoferrin Augmentation of the BCG Vaccine Leads to Increased Pulmonary Integrity.
Medium term treatment of stable stage cystic fibrosis with recombinant human DNase I.
Nebulised hypertonic saline for cystic fibrosis.
New treatment strategies in cystic fibrosis: rhDNase.
Proteins in bronchial secretion of children with chronic pulmonary diseases. I. Relation to clinical diagnosis.
Proteins in bronchial secretion of children with chronic pulmonary diseases. II. Relation to bronchoscopic and bronchographic examination.
Protocol for the Lactoferrin Infant Feeding Trial (LIFT): a randomised trial of adding lactoferrin to the feeds of very-low birthweight babies prior to hospital discharge.
Recombinant human deoxyribonuclease for cystic fibrosis.
Recombinant human DNase I in cystic fibrosis patients with severe pulmonary disease: a short-term, double-blind study followed by six months open-label treatment.
Rheology of cystic fibrosis sputum after in vitro treatment with hypertonic saline alone and in combination with recombinant human deoxyribonuclease I.
Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.
Two years experience with recombinant human DNase I in the treatment of pulmonary disease in cystic fibrosis.
[Clinical experiences in the treatment of purulent lung diseases with desoxyribonuclease.]
[Clinico-diagnostic role of ferritin and lactoferrin assays in benign and malignant affections of lungs and pleura]
Lung Diseases, Interstitial
Serum level of DNase1l3 in patients with dermatomyositis/polymyositis, systemic lupus erythematosus and rheumatoid arthritis, and its association with disease activity.
Lung Injury
Aerosolized bovine lactoferrin reduces lung injury and fibrosis in mice exposed to hyperoxia.
DNaseI Protects against Paraquat-Induced Acute Lung Injury and Pulmonary Fibrosis Mediated by Mitochondrial DNA.
Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.
Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury.
Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury.
Neutrophil extracellular traps promote cadmium chloride-induced lung injury in mice.
Protocol for TRAUMADORNASE: a prospective, randomized, multicentre, double-blinded, placebo-controlled clinical trial of aerosolized dornase alfa to reduce the incidence of moderate-to-severe hypoxaemia in ventilated trauma patients.
Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis.
Lung Neoplasms
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.
Bovine lactoferrin inhibits lung cancer growth through suppression of both inflammation and expression of vascular endothelial growth factor.
Characteristic variations of serum alkaline DNase activity in relation to response to therapy and tumor prognosis in human lung cancer.
Clinical applications of bioactive milk components.
Colicin N Mediates Apoptosis and Suppresses Integrin-Modulated Survival in Human Lung Cancer Cells.
Expression of an X-family DNA polymerase, pol lambda, in the respiratory epithelium of non-small cell lung cancer patients with habitual smoking.
HB-EGF Is a Promising Therapeutic Target for Lung Cancer with Secondary Mutation of EGFR(T790M).
Hyaluronate/lactoferrin layer-by-layer-coated lipid nanocarriers for targeted co-delivery of rapamycin and berberine to lung carcinoma.
Inhalable multi-compartmental phospholipid enveloped lipid core nanocomposites for localized mTOR inhibitor/herbal combined therapy of lung carcinoma.
Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer.
Knockdown of POLE2 expression suppresses lung adenocarcinoma cell malignant phenotypes in vitro.
Prediction and identification of transcriptional regulatory elements at the lung cancer-specific DKK1 locus.
Regulation of DNA Polymerase POLD4 Influences Genomic Instability in Lung Cancer.
Soluble tumor-associated markers in lung cancer extracts.
Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci.
The genomic structure of the human UBE1L gene.
The therapeutic potential of attenuated diphtheria toxin delivered by an adenovirus vector with survivin promoter on human lung cancer cells.
XPG is Modulated by miR-4715-3p and rs873601 Genotypes in Lung Cancer.
[Clinico-diagnostic role of ferritin and lactoferrin assays in benign and malignant affections of lungs and pleura]
[Pulmonary medicine. Four major papers in 2010-2011].
Lupus Erythematosus, Cutaneous
Apoptosis of keratinocytes and serum DNase I activity in patients with cutaneous lupus erythematosus: relationship with clinical and immunoserological parameters.
Lupus Erythematosus, Systemic
A new specific assay for the detection of DNA immune complexes: its relevance in SLE.
A nonsense mutation in exon 2 of the DNase I gene is not present in UK subjects with systemic lupus erythematosus and Graves' disease: Comment on the article by Rood et al.
An autosomal recessive DNASE1L3-related autoimmune disease with unusual clinical presentation mimicking systemic lupus erythematosus.
ANCA with specificity for lactoferrin in systemic lupus erythematosus (SLE).
Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.
Anti-neutrophil cytoplasmic antibodies in childhood systemic lupus erythematosus.
Antilactoferrin antibody in systemic lupus erythematosus.
Antinucleosome antibodies and decreased deoxyribonuclease activity in sera of patients with systemic lupus erythematosus.
Arg206Cys substitution in DNASE1L3 causes a defect in DNASE1L3 protein secretion that confers risk of systemic lupus erythematosus.
Assessment of Deoxyribonuclease Activity in Serum Samples of Patients With Systemic Lupus Erythematosus: Fluorescence-Based Method Versus ELISA.
Association between severe disease course and nephritis with Q222R polymorphism in DNAse I gene among lupus patients: An Argentine multicenter study.
Association of a non-synonymous single-nucleotide polymorphism of DNASEI with SLE susceptibility.
Association of the DNASE1L3 rs35677470 polymorphism with systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis: Structural biological insights.
Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus.
Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis.
Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients.
Contrast-enhanced magnetic resonance imaging (MS-325) in a murine model of systemic lupus erythematosus.
Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin.
Degradation of circulating DNA by extracorporeal circulation over nuclease immobilized on nylon microcapsules.
Deoxyribonuclease 1-Mediated Clearance of Circulating Chromatin Prevents From Immune Cell Activation and Pro-inflammatory Cytokine Production, a Phenomenon Amplified by Low Trap1 Activity: Consequences for Systemic Lupus Erythematosus.
Deoxyribonuclease I gene polymorphism and susceptibility to systemic lupus erythematosus.
DNA polymerase activity and antibody against it in sera of patients with systemic lupus erythematosus.
DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features.
DNase 1 and systemic lupus erythematosus.
DNASE I mutation and systemic lupus erythematosus in a Spanish population: comment on the article by Tew et al.
DNase1 activity in systemic lupus erythematosus patients with and without nephropathy.
DNase1 exon2 analysis in Tunisian patients with rheumatoid arthritis, systemic lupus erythematosus and Sjögren syndrome and healthy subjects.
Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.
Dnase1L3 Regulates Inflammasome-Dependent Cytokine Secretion.
DNaseI in pathogenesis of systemic lupus erythematosus.
Dnases in health and disease.
Histopathology of lupus-like nephritis in Dnase1-deficient mice in comparison to NZB/W F1 mice.
Homogeneous Immunochemical Assay on the Lateral Flow Strip for Measurement of DNase I Activity.
Identification of the functional alleles of the nonsynonymous single-nucleotide polymorphisms potentially implicated in systemic lupus erythematosus in the human deoxyribonuclease I gene.
Improved potency of hyperactive and actin-resistant human DNase I variants for treatment of cystic fibrosis and systemic lupus erythematosus.
Influence of HumDN1 VNTR polymorphism on DNASE1 expression in systemic lupus erythematosus and rheumatoid arthritis.
Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus.
Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)-prone NZB/NZW mice by a new radial enzyme diffusion assay.
Molecular analysis of HumDN1 VNTR polymorphism of the human deoxyribonuclease I in systemic lupus erythematosus.
Mutation of DNASE1 in people with systemic lupus erythematosus.
No evidence of mutation in exon 2 of DNAse1 gene in Chinese patients with systemic lupus erythematosus.
Novel DNASE I mutations related to systemic lupus erythematosus.
Pharmacodynamics of recombinant human DNase I in serum.
Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction.
Plasma lactoferrin and neutrophil elastase in rheumatoid arthritis and systemic lupus erythematosus.
Quartz crystal microbalance immunosensor for the detection of antibodies to double-stranded DNA.
Refractory and Fatal Presentation of Severe Autoimmune Hemolytic Anemia in a Child With the DNASE1L3 Mutation Complicated With an Additional DOCK8 Variant.
Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus.
Serum DNase I activity in systemic lupus erythematosus: correlation with immunoserological markers, the disease activity and organ involvement.
Serum DNase I, soluble Fas/FasL levels and cell surface Fas expression in patients with SLE: a possible explanation for the lack of efficacy of hrDNase I treatment.
Serum level of DNase1l3 in patients with dermatomyositis/polymyositis, systemic lupus erythematosus and rheumatoid arthritis, and its association with disease activity.
Single nucleotide polymorphisms of deoxyribonuclease I and their expression in Chinese systemic lupus erythematosus patients.
Studies on desoxyribonuclease in systemic lupus erythematosus; non-participation of serum desoxyribonuclease in the L.E. phenomenon.
Study of DNASE I gene polymorphisms in systemic lupus erythematosus susceptibility.
Taming hyperactive hDNase I: Stable inducible expression of a hyperactive salt- and actin-resistant variant of human deoxyribonuclease I in CHO cells.
The A/T mutation in exon 2 of the DNASE1 gene is not present in Tunisian patients with systemic lupus erythematosus or in healthy subjects.
The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus.
The isolation of the antibody moieties of immune complexes from serum by the pepsin digestion of conglutinin-anti-conglutinin complexes.
Type C oncornavirus isolation studies in systemic lupus erythematosus. II. Attempted detection by viral RNA-dependent DNA polymerase assay.
[Deoxyribonuclease I gene expression in systemic lupus erythematosus patients]
[DNA antibodies, DNA and DNAase plasma activity in children suffering from systemic lupus erythematosus]
[DNAse II from phagocytes in the study of the pathogenesis of systemic lupus erythematosus]
[Levels of the C 4 component of the complement, lactoferrin and leukocytic thermostabile alpha glycoprotein during the treatment of patients with systemic rheumatic diseases]
[Significance of DNAase activity of blood in systemic lupus erythematosus]
[Some proteins of acute phase of inflammation in differential diagnostics of rheumatoid arthritis]
[Studies on DNase I activity and its heat-labile inhibitor in systemic lupus erythematosus]
[Studies on Dnase I activity in systemic lupus erythematosus]
Lupus Nephritis
Acquired Loss of Renal Nuclease Activity Is Restricted to DNaseI and Is an Organ-Selective Feature in Murine Lupus Nephritis.
Anti-DNA antibodies in the urine of lupus nephritis patients.
Anti-dsDNA antibodies promote initiation, and acquired loss of renal Dnase1 promotes progression of lupus nephritis in autoimmune (NZBxNZW)F1 mice.
Clinical significance of antineutrophil cytoplasmic autoantibodies with specificity for lactoferrin in renal diseases.
Critical comparative analyses of anti-alpha-actinin and glomerulus-bound antibodies in human and murine lupus nephritis.
Highly cationic anti-DNA antibodies in patients with lupus nephritis analyzed by two-dimensional electrophoresis and immunoblotting.
Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis.
Lupus nephritis progression in Fc?RIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.
Lupus nephritis: enigmas, conflicting models and an emerging concept.
Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression.
Progression of murine lupus nephritis is linked to acquired renal Dnase1 deficiency and not to up-regulated apoptosis.
Recombinant human Dnase I (rhDNase) in patients with lupus nephritis.
Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis.
Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e.
Lyme Disease
Hospitalized Children With Encephalitis in the United States: A Pediatric Health Information System Database Study.
Lymphadenitis
Histochemical studies of obstructive adenitis in human submandibular salivary glands. I. Immunohistochemical demonstration of lactoferrin, lysozyme and carcinoembryonic antigen.
Outbreak with clonally related isolates of Corynebacterium ulcerans in a group of water rats.
The distribution of ferritin, lactoferrin and transferrin in granulomatous lymphadenitis of bovine paratuberculosis.
Lymphatic Metastasis
Correlation between HPV status at T and N sites of oropharyngeal squamous cell carcinomas.
Lymphocytic Choriomeningitis
Mast Cells Modulate Antigen-Specific CD8+ T Cell Activation During LCMV Infection.
Lymphogranuloma Venereum
Absence of lymphogranuloma venereum strains among rectal Chlamydia trachomatis outer membrane protein A genotypes infecting women and men who have sex with men in Birmingham, Alabama.
Lymphoma
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.
A novel mutation in the UL54 gene of human cytomegalovirus isolates that confers resistance to foscarnet.
A phase-1 trial of bexarotene and denileukin diftitox in patients with relapsed or refractory cutaneous T-cell lymphoma.
Abatement of Sézary syndrome lesions following treatment with acyclovir.
Analysis of chromatin changes associated with the expression of globin and non-globin genes in cell hybrids between erythroid and other cells.
Anti-CD3 recombinant diphtheria immunotoxin therapy of cutaneous T cell lymphoma.
Antitumor effects of antibody-diphtheria toxin conjugates. II. Immunotherapy with conjugates directed against tumor antigens induced by simian virus 40.
Beta 2-microglobulin, lysozyme and lactoferrin in cerebrospinal fluid in patients with lymphoma or leukaemia: relationship to CNS involvement and the effect of prophylactic intrathecal treatment with methotrexate.
Biological correlates of acute hypersensitivity events with DAB(389)IL-2 (denileukin diftitox, ONTAK) in cutaneous T-cell lymphoma: decreased frequency and severity with steroid premedication.
Bovine lactoferrin and Lactoferricin inhibit tumor metastasis in mice.
Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice.
Characterization of an RNA-directed DNA-polymerase from a cell line derived from a radiation-induced lymphoma in mice.
Duodenal expression of antimicrobial peptides in dogs with idiopathic inflammatory bowel disease and intestinal lymphoma.
Establishment of a detection assay for DNA endonuclease activity and its application in the screening and prognosis of malignant lymphoma.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans.
Interferon rapidly induces modifications of chromatin sensitivity to DNase I in Daudi lymphoma cells.
Investigations into the association of retroviruses with ovine lymphoma.
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Modulation of diphthamide synthesis by 5'-deoxy-5'-methylthioadenosine in murine lymphoma cells.
Nuclear metabolic changes induced by tumor necrosis factor in Daudi lymphoma cells; a multiparametric analysis.
Nucleoprotein complexes released from lymphoma nuclei that contain the abl oncogene and RNA and DNA polymerase and RNA primase activities.
Rearranged and germline immunoglobulin kappa genes: different states of DNase I sensitivity of constant kappa genes in immunocompetent and nonimmune cells.
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies.
Regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of SJL/J mice: role of Ikaros, demethylation, and chromatin structural change in the transcriptional activation of mammary tumor virus superantigen.
Sequence-specific interactions of nuclear factors with conserved sequences of human class II major histocompatibility complex genes.
Similar actions of glucocorticoids and calcium on the regulation of apoptosis in S49 cells.
The relation of argyrophilic proteins of nucleolar organizer regions (AgNORs) to the proportions of Ki-67 or DNA polymerase alpha-reacting cells in non-Hodgkin's lymphomas.
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.
Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.
Value of combined approach with thallium-201 single-photon emission computed tomography and Epstein-Barr virus DNA polymerase chain reaction in CSF for the diagnosis of AIDS-related primary CNS lymphoma.
Variations in serum alkaline DNase activity. A new means for therapeutic monitoring of malignant lymphomas.
[Cytotoxicity of the B subunit of diphtheria toxin to human histocytic lymphoma U937]
[Successful interferon-alpha treatment of hepatitis B developing during chemotherapy of malignant lymphoma]
Lymphoma, B-Cell
Denileukin Diftitox (Ontak) as Maintenance Therapy for Peripheral T-Cell Lymphomas: Three Cases with Sustained Remission.
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans.
Increased sensitivity of B-cell clonality analysis in formalin-fixed and paraffin-embedded B-cell lymphoma samples using an enzyme blend with both 5'-->3' DNA polymerase and 3'-->5' exonuclease activity.
Integrin alpha 10, CD44, PTEN, cadherin-11 and lactoferrin expressions are potential biomarkers for selecting patients in need of central nervous system prophylaxis in diffuse large B-cell lymphoma.
Rearranged and germline immunoglobulin kappa genes: different states of DNase I sensitivity of constant kappa genes in immunocompetent and nonimmune cells.
Lymphoma, Large B-Cell, Diffuse
Integrin alpha 10, CD44, PTEN, cadherin-11 and lactoferrin expressions are potential biomarkers for selecting patients in need of central nervous system prophylaxis in diffuse large B-cell lymphoma.
Lymphoma, Non-Hodgkin
DNA polymerase chain reaction using fine needle aspiration biopsy smears to evaluate non-Hodgkin's lymphoma.
Presence of DNA polymerase in lymphosarcoma in northern pike (Esox lucius).
Lymphoma, T-Cell, Cutaneous
Abatement of Sézary syndrome lesions following treatment with acyclovir.
Anti-CD3 recombinant diphtheria immunotoxin therapy of cutaneous T cell lymphoma.
Biologic correlates of response and survival in patients with cutaneous T-cell lymphoma treated with denileukin diftitox.
Immunotoxins for targeted cancer therapy.
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies.
Recombinant immunotoxins for the treatment of chemoresistant hematologic malignancies.
Recombinant immunotoxins for the treatment of haematological malignancies.
Recombinant toxins for the treatment of cancer.
Toxin-labeled monoclonal antibodies.
Treatment of refractory peripheral T-cell lymphoma with denileukin diftitox (ONTAK).
UVA1 irradiation induces deoxyribonuclease dependent apoptosis in cutaneous T-cell lymphoma in vivo.
Lymphoma, T-Cell, Peripheral
Treatment of refractory peripheral T-cell lymphoma with denileukin diftitox (ONTAK).
lysozyme deficiency
Lactoferrin and lysozyme deficiency in airway secretions: association with the development of bronchopulmonary dysplasia.
Malaria
Circulating Epstein-Barr virus-carrying B cells in acute malaria.
Comparison of six commercially-available DNA polymerases for direct PCR.
Detection of Rickettsia africae in patients and ticks along the coastal region of Cameroon.
Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria at sentinel sites in Mozambique, 2015.
Gateways to clinical trials.
Generation of Rodent Malaria Parasites with a High Mutation Rate by Destructing Proofreading Activity of DNA Polymerase ?
Molecular analysis of non-specific protection against murine malaria induced by BCG vaccination.
Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase ?.
Partial purification and characterization of DNA polymerase beta-like enzyme from Plasmodium falciparum.
Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity.
The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the malaria parasite Plasmodium falciparum.
The proofreading activity of Pfprex from Plasmodium falciparum can prevent mutagenesis of the apicoplast genome by oxidized nucleotides.
Use of streamline chelating for capture and purification of poly-His-tagged recombinant proteins.
Malaria, Cerebral
Immunological Evaluation of Synthetic Glycosylphosphatidylinositol Glycoconjugates as Vaccine Candidates against Malaria.
Malignant Catarrh
First report of malignant catarrhal fever in a captive pudu (Pudu puda).
Malnutrition
Cerebellar DNA polymerase activity in hypothyroid and malnourished rats.
DNA polymerase activity in normal and malnourished rat placentas.
DNA polymerase and thymidine kinase activities in different regions of rat brain during postnatal development: effect of undernutrition.
Milk with and without lactoferrin can influence intestinal damage in a pig model of malnutrition.
Marek Disease
Difference in DNA polymerase activity in lymphoid tumor between avian lymphoid leukosis and Marek's disease.
Genome-wide mapping of DNase I hypersensitive sites and association analysis with gene expression in MSB1 cells.
Identification and characterization of a Marek's disease virus gene encoding DNA polymerase.
Marek's disease herpesvirus-induced DNA polymerase.
Mechanism of phosphonoacetate inhibition of herpesvirus-induced DNA polymerase.
Properties of the DNA polymerase induced by Marek's disease herpesvirus, strain GA, upon infection of duck embryo fibroblasts.
Massive Hepatic Necrosis
Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice.
Fatal hepatitis B virus reactivation in a chronic myeloid leukemia patient during imatinib mesylate treatment.
Fulminant hepatitis B in successive female sexual partners of two anti-HBe-positive males.
Natural history of hepatitis B virus infection in renal transplant recipients--a fifteen-year follow-up.
Mastitis
Advances in lactoferrin research concerning bovine mastitis.
Antibacterial activity of bovine lactoferrin hydrolysate against mastitis pathogens and its effect on superoxide production of bovine neutrophils.
Antibacterial effect of bovine lactoferrin against udder pathogens.
Bacterial deoxyribonuclease production and its possible influence on mastitis detection.
Binding of bovine lactoferrin to Streptococcus dysgalactiae subsp. dysgalactiae isolated from cows with mastitis.
Bovine lactoferrin receptors in Staphylococcus aureus isolated from bovine mastitis.
Change in viable bacterial count during preservation of milk derived from dairy cows with subclinical mastitis and its relationship with antimicrobial components in milk.
Changes in lactoferrin, immunoglobulin G, bovine serum albumin, and alpha-lactalbumin during acute experimental and natural coliform mastitis in cows.
Characterisation of single nucleotide polymorphisms identified in the bovine lactoferrin gene sequences across a range of dairy cow breeds.
Characterization of bovine mammary gland dry secretions and their proteome from the end of lactation through day 21 of the dry period.
Comparison between lactoferrin and subepithelial matrix protein binding in Staphylococcus aureus associated with bovine mastitis.
Concentration of lactoferrin in milk of normal lactating cows and changes occurring during mastitis.
Concentrations of bovine lactoferrin and citrate in milk during experimental endotoxin mastitis in early- versus late-lactating dairy cows.
Crosstalk between coagulation and inflammation in mastitis and metritis in dairy cows.
Detection and characterization of PCR-SSCP markers of the bovine lactoferrin gene for clinical mastitis.
Differential expression of immune response genes associated with subclinical mastitis in dairy buffaloes.
DNase I improves blood-milk barrier integrity and alleviates inflammation induced by Staphylococcus aureus during mastitis.
Dynamics of lingual antimicrobial peptide, lactoferrin concentrations and lactoperoxidase activity in the milk of cows treated for clinical mastitis
Dynamics of lingual antimicrobial peptide, lactoferrin concentrations and lactoperoxidase activity in the milk of cows treated for clinical mastitis.
Effect of bovine lactoferrin on the internalization of coagulase-negative staphylococci into bovine mammary epithelial cells under in-vitro conditions.
Effect of combination therapy with lactoferrin and antibiotics against staphylococcal mastitis on drying cows.
Effect of infusing lactoferrin hydrolysate into bovine mammary glands with subclinical mastitis.
Effect of lactoferrin in combination with penicillin on the morphology and the physiology of Staphylococcus aureus isolated from bovine mastitis.
Effects of bovine lactoferrin by the intramammary infusion in cows with staphylococcal mastitis during the early non-lactating period.
Efficacy of a lactoferrin-penicillin combination to treat {beta}-lactam-resistant Staphylococcus aureus mastitis.
Enhancement of the activity of novobiocin against Escherichia coli by lactoferrin.
Experimental mastitis with Escherichia coli: kinetics of bacteriostatic and bactericidal activities.
Growth inhibition of Escherichia coli and Klebsiella pneumoniae during involution of the bovine mammary gland: relation to secretion composition.
Identification of polymorphism in exons 7 and 12 of lactoferrin gene and its association with incidence of clinical mastitis in Murrah buffalo.
Immune response during the onset of coliform mastitis in dairy cows vaccinated with STARTVAC®.
Inflammatory effect of cleaved bovine lactoferrin by elastase on staphylococcal mastitis.
Inhibition of mastitic bacteria by bovine milk apo-lactoferrin evaluated by in vitro microassay of bacterial growth.
Lactoferrin affects the adherence and invasion of Streptococcus dysgalactiae ssp. dysgalactiae in mammary epithelial cells.
Lactoferrin against Staphylococcus aureus Mastitis. Lactoferrin alone or in combination with penicillin G on bovine polymorphonuclear function and mammary epithelial cells colonisation by Staphylococcus aureus.
Lactoferrin and lysozyme in milk during acute mastitis and their inhibitory effect in Delvotest P.
Lactoferrin concentration in milk of bovine clinical mastitis.
Lactoferrin gene promoter variants and their association with clinical and subclinical mastitis in indigenous and crossbred cattle.
Mastitis and immunological factors in breast milk of lactating women in Malawi.
Mastitis and transmission of human immunodeficiency virus through breast milk.
Mastitis in rural Gambian mothers and the protection of the breast by milk antimicrobial factors.
Mid-infrared prediction of lactoferrin content in bovine milk: potential indicator of mastitis.
Polymorphisms in the promoter region of the bovine lactoferrin gene influence milk somatic cell score and milk production traits in Chinese Holstein cows.
Reduced lactational performance following intravenous endotoxin administration to dairy cows.
Single nucleotide polymorphisms in immunity-related genes and their association with mastitis in Chilean dairy cattle.
Single nucleotide polymorphisms, haplotypes and combined genotypes of lactoferrin gene and their associations with mastitis in Chinese Holstein cattle.
Study on the polymorphism of bovine lactoferrin gene and its relationship with mastitis.
The efficacy of bovine lactoferrin in the treatment of cows with experimentally induced Escherichia coli mastitis.
Transgenic cows that produce recombinant human lactoferrin in milk are not protected from experimental Escherichia coli intramammary infection.
Two single nucleotide polymorphisms sites in ?1-AT gene and their association with somatic cell score in Chinese Holstein cows.
Two splice variants of the bovine lactoferrin gene identified in Staphylococcus aureus isolated from mastitis in dairy cattle.
Variation of lactoferrin and mastitis and their heritabilities.
Variations in the levels of acute-phase proteins and lactoferrin in serum and milk during bovine subclinical mastitis.
[Defense mechanisms of the bovine mammary gland]
[Do lactoferrin, lysozyme and the lactoperoxidase-thiocyanate-hydrogen peroxide-system cause negative microbiological results in mastitis secretions?]
[Genetic polymorphism in 5'-flanking region of the lactoferrin gene and its associations with mastitis in Chinese Holstein cows.]
Mastocytoma
Prostaglandin D2 lowers nuclear DNA polymerase activity in cultured mastocytoma cells.
Maxillary Sinusitis
[Streptokinase and streptodornase in chronic maxillary sinusitis.]
[Streptokinase and streptodornase in maxillary sinusitis.]
[Streptokinase, streptodornase and chronic maxillary sinusitis.]
[The influence of local and combined acute suppurative Highmore maxillary sinusitis on the serum lactoferrin and interleukin-8 levels in the children].
Measles
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Measles virus RNA is not detected in inflammatory bowel disease using hybrid capture and reverse transcription followed by the polymerase chain reaction.
Medulloblastoma
DNA polymerase ? deficiency in the p53 null cerebellum leads to medulloblastoma formation.
Ultrastructural detection of DNA strand breaks in apoptotic neural cells by in situ end-labelling techniques.
Meibomian Gland Dysfunction
Decreased tear lipocalin concentration in patients with meibomian gland dysfunction.
Tear eicosanoids in healthy people and ocular surface disease.
Tear Lactoferrin and Features of Ocular Allergy in Different Severities of Meibomian Gland Dysfunction.
Melanoma
12(S)-hydroxyeicosatetraenoic acid increases the actin microfilament content in B16a melanoma cells: a protein kinase-dependent process.
3,4-Dihydroxybenzylamine: an improved dopamine analog cytotoxic for melanoma cells in part through oxidation products inhibitory to dna polymerase.
A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice.
Actin in B16 melanoma cells of differing metastatic potential. Effects of trypsin and serum.
Angiosarcoma Arising from the Tongue of an 11-Year-Old Girl with Xeroderma Pigmentosum.
Anti-tumor activity of Acinetobacter baumannii outer membrane protein A on dendritic cell-based immunotherapy against murine melanoma.
Antitumor and biological effects of black pine (pinus nigra) pollen nuclease.
Azelaic acid: mode of action at cellular and subcellular levels.
Biochemical and immunological characterization of a reverse transcriptase from human melanoma tissue.
Bovine lactoferrin and Lactoferricin inhibit tumor metastasis in mice.
Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice.
Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.
Characterization of a DNA polymerase activity in cultured human melanoma cells that copies poly(2'-O-methylcytidylate).
Characterization of cells obtained by mechanical and enzymatic means from human melanoma, sarcoma, and lung tumors.
Clinical Experience of Treatment of Metastatic Melanoma and Solid Tumours Adopting a Derivative of Diphtheria Toxin: Cross-reacting Material 197.
Comparison of hyperthermia radiosensitization and DNA polymerase inactivation in human normal and melanoma cell lines of different radiosensitivities.
Corynebacterium diphtheriae: Diphtheria Toxin, the tox Operon, and Its Regulation by Fe2+ Activation of apo-DtxR.
Defective DNA endonuclease activity on anthramycin treated DNA in xeroderma pigmentosum and mouse melanoma cells.
Distribution of DNA polymerase Cm in normal and malignant human tissues.
DNA endonuclease activities associated with melanoma cell chromatin.
Effect of Ribonuclease A and Deoxyribonuclease I on Immunostaining of Ki-67 in Cultured Melanoma Cells.
Expression of the proliferation-associated Ki-67 antigen of transferrin receptors and of DNA polymerase alpha in human tumour lines: implications for in vitro chemoresistance.
Functional analysis of the human calcyclin gene promoter in a panel of human melanoma cell lines.
Immunolocalization of lactoferrin in surgically resected pigmented skin lesions.
Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma.
Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice.
Lactoferrin inhibits melanogenesis by down-regulating MITF in melanoma cells and normal melanocytes.
Levodopa and dopamine analogs as DNA polymerase inhibitors and antitumor agents in human melanoma.
Liposomalization of lactoferrin enhanced its anti-tumoral effects on melanoma cells.
Mechanisms underlying DNA damage resistance in a Xiphophorus melanoma cell line.
Melanoma cells replicate through chemotherapy by reducing levels of key homologous recombination protein RAD51 and increasing expression of translesion synthesis DNA polymerase ?.
MiTF regulates cellular response to reactive oxygen species through transcriptional regulation of APE-1/Ref-1.
Mitochondrial DNA polymerases from yeast to man: a new family of polymerases.
Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth.
Nuclear deoxyribonuclease activities in human lymphoblastoid and mouse melanoma cells. A comparative study.
Nuclear DNA endonuclease activities on partially apurinic/apyrimidinic DNA in normal human and xeroderma pigmentosum lymphoblastoid and mouse melanoma cells.
Receptor-mediated endocytosis of urokinase-type plasminogen activator is regulated by cAMP-dependent protein kinase.
Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy.
Stepdown hyperthermia in human melanoma cells: effects on protracted mild hyperthermia for survival and DNA polymerase inactivation.
The human melanoma associated protein melanotransferrin promotes endothelial cell migration and angiogenesis in vivo.
The killing effect of 4-S-cysteaminylphenol, a newly synthesised melanin precursor, on B16 melanoma cell lines.
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
Tumor Lymphatic Function Regulates Tumor Inflammatory and Immunosuppressive Microenvironments.
[Inhibition of Invasive Properties of Murine Melanoma by Bovine Pancreatic DNase I In Vitro and In Vivo].
Melanoma, Experimental
Hypoxia influences linearly patterned programmed cell necrosis and tumor blood supply patterns formation in melanoma.
Quantitative estimation of tumor metastasis by measurement of DNA polymerase activity.
[Inhibition of Invasive Properties of Murine Melanoma by Bovine Pancreatic DNase I In Vitro and In Vivo].
Melioidosis
Development of an immunoassay using recombinant outer membrane protein A and flagellin for diagnosis of goats with melioidosis.
Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-? release in Burkholderia thailandensis infection in vitro.
Meningioma
Hormonal dependency of cerebral meningiomas. Part 2: In vitro effect of steroids, bromocriptine, and epidermal growth factor on growth of meningiomas.
Meningitis
Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.
Brain damage in newborn rat model of meningitis by Enterobacter sakazakii: a role for outer membrane protein A.
Calprotectin and lactoferrin in the cerebrospinal fluid; biomarkers utilisable for differential diagnostics of bacterial and aseptic meningitis?
Characterization of Escherichia coli serogroups causing meningitis, sepsis and enteritis. II. Classification of Escherichia coli O78 strains by phage sensitivity, colicin type and antibiotic resistance.
Deciphering the roles of outer membrane protein A extracellular loops in the pathogenesis of Escherichia coli K1 meningitis.
Discovery and development of a synthetic peptide derived from lactoferrin for clinical use.
DNase Treatment Prevents Cerebrospinal Fluid Block in Early Experimental Pneumococcal Meningitis.
Experimental validation of the predicted binding site of Escherichia coli K1 outer membrane protein A to human brain microvascular endothelial cells; identification of critical mutations that prevent E coli meningitis.
Extracellular loops of the Eschericia coli outer membrane protein A contribute to the pathogenesis of meningitis.
Gateways to clinical trials.
Identification of minimum carbohydrate moiety in N-glycosylation sites of brain endothelial cell glycoprotein 96 for interaction with Escherichia coli K1 outer membrane protein A.
Lactoferrin, C-reactive protein, alpha-1-antitrypsin and immunoglobulin GA in cerebrospinal fluid in meningitis.
Levels of antimicrobial molecules defensin and lactoferrin are elevated in the cerebrospinal fluid of children with meningitis.
Meningitis due to Klebsiella pneumoniae; report of two cases, with the use of streptokinase and streptodornase in one case.
Meningitis due to pseudomonas aeruginosa; intrathecal treatment with streptokinase and streptodornase and intramuscular and intrathecal treatment with neomycin.
Outer membrane protein A (OmpA) of Cronobacter sakazakii binds fibronectin and contributes to invasion of human brain microvascular endothelial cells.
Possible Cross-Reactivity between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and Death.
Recombinant outer membrane protein A fragments protect against Escherichia coli meningitis.
Regulation of Toll-like receptor 2 interaction with Ecgp96 controls Escherichia coli K1 invasion of brain endothelial cells.
Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis.
STAPHYLOCOCCAL MENINGITIS COMPLICATED BY SUBARACHNOID BLOCK. REPORT OF A CASE SUCCESSFULLY TREATED BY INTRATHECAL STREPTOKINASE AND STREPTODORNASE.
Studies in experimental meningitis in rhesus monkeys. III. The effect of intracisternal injection of streptokinase and streptodornase on the exudate of experimental meningitis.
[Level of lactoferrin in serum and cerebrospinal fluid of patients with meningitis]
[Serious staphylococcic meningitis with purulent blockage; spectacular action of streptokinase and streptodornase.]
[Streptokinase and streptodornase in pleurisy and meningitis therapy.]
[Streptokinase and streptodornase in the treatment of purulent meningitis.]
Meningitis, Aseptic
Levels of antimicrobial molecules defensin and lactoferrin are elevated in the cerebrospinal fluid of children with meningitis.
[Level of lactoferrin in serum and cerebrospinal fluid of patients with meningitis]
Meningitis, Bacterial
Lactoferrin, C-reactive protein, alpha-1-antitrypsin and immunoglobulin GA in cerebrospinal fluid in meningitis.
Levels of antimicrobial molecules defensin and lactoferrin are elevated in the cerebrospinal fluid of children with meningitis.
[Level of lactoferrin in serum and cerebrospinal fluid of patients with meningitis]
Meningitis, Escherichia coli
Recombinant outer membrane protein A fragments protect against Escherichia coli meningitis.
Meningitis, Pneumococcal
Crystalline pancreatic desoxyribonuclease as an adjunct to the treatment of pneumococcal meningitis.
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis.
Meningitis, Viral
Cerebrospinal fluid lactoferrin in bacterial and viral meningitis.
Meningococcal Infections
Analysis of the human Ig isotype response to lactoferrin binding protein A from Neisseria meningitidis.
Comparison of the abilities of different protein sources of iron to enhance Neisseria meningitidis infection in mice.
Mesothelioma
Diagnostic value of lactoferrin analysis in pleural effusions.
Expression of the proliferation-associated Ki-67 antigen of transferrin receptors and of DNA polymerase alpha in human tumour lines: implications for in vitro chemoresistance.
Mesothelioma, Malignant
67Ga-transferrin and 67Ga-lactoferrin binding to tumor cells: specific versus nonspecific glycoprotein-cell interaction.
Cure of experimental human malignant mesothelioma in athymic mice by diphtheria toxin.
Metabolic Syndrome
Enteric lactoferrin attenuates the development of high-fat and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis in Microminipigs.
Inflammation Is Strongly Associated With Cardiorespiratory Fitness, Sex, BMI, and the Metabolic Syndrome in a Self-reported Healthy Population: HUNT3 Fitness Study.
Lactoferrin dampens high-fructose corn syrup-induced hepatic manifestations of the metabolic syndrome in a murine model.
Microaneurysm
Retinal microangiopathy in a mouse model of inducible mural cell loss.
Microcephaly
Defective DNA Polymerase ?-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism.
Neuroanatomical study of somatomotor cortex in microcephalic mice induced by cytosine arabinoside.
Microphthalmos
Analysis of lens cell fate and eye morphogenesis in transgenic mice ablated for cells of the lens lineage.
Milk Hypersensitivity
Recent perspective on cow's milk allergy and dairy nutrition.
Mitochondrial Diseases
A Clinical, Neuropathological and Genetic Study of Homozygous A467T POLG-Related Mitochondrial Disease.
A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme.
Biolayer Interferometry: A Novel Method to Elucidate Protein-Protein and Protein-DNA Interactions in the Mitochondrial DNA Replisome.
Mitochondrial disorders of DNA polymerase ? dysfunction: from anatomic to molecular pathology diagnosis.
Mutations in human DNA polymerase ? confer unique mechanisms of catalytic deficiency that mirror the disease severity in mitochondrial disorder patients.
Molluscum Contagiosum
Cidofovir diphosphate inhibits molluscum contagiosum virus DNA polymerase activity.
Strategy for identifying the gene encoding the DNA polymerase of molluscum contagiosum virus type 1.
Monkeypox
Orthopoxvirus DNA: a comparison of restriction profiles and maps.
Mouth Neoplasms
Effects of CRM197, a specific inhibitor of HB-EGF, in oral cancer.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Pepsin-digested bovine lactoferrin induces apoptotic cell death with JNK/SAPK activation in oral cancer cells.
Serum alkaline deoxyribonuclease in oral cancer and premalignant lesions.
Mucocutaneous Lymph Node Syndrome
Absence of significant RNA-dependent DNA polymerase activity in lymphocytes from patients with Kawasaki syndrome.
Failure to confirm the presence of a retrovirus in cultured lymphocytes from patients with Kawasaki syndrome.
Mucormycosis
Lactoferrin, a potential iron-chelator as an adjunct treatment for mucormycosis - A comprehensive review.
Mucositis
Evaluation of bovine lactoferrin as a topical therapy for chemotherapy-induced mucositis in the golden Syrian hamster.
Lactoferrin reduces methotrexate-induced small intestinal damage, possibly through inhibition of GLP-2-mediated epithelial cell proliferation.
Sucralfate mouth washing in the prevention of radiation-induced mucositis: a placebo-controlled double-blind randomized study.
Multiple Myeloma
PCR with degenerate primers for highly conserved DNA polymerase gene of the herpesvirus family shows neither human herpesvirus 8 nor a related variant in bone marrow stromal cells from multiple myeloma patients.
Multiple Sclerosis
Cerebrospinal fluid CD4+ T cells from a multiple sclerosis patient cross-recognize Epstein-Barr virus and myelin basic protein.
Ultrastructural features of viral leukoencephalomyelitis of goats.
Mumps
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Sequence variation of the P gene among mumps virus strains.
Muscle Spasticity
[Immunoglobulins, lactoferrin and the secretor state and their relationship to spastic bronchitis in the infant and small child]
Muscular Atrophy, Spinal
Newborn Screening for Spinal Muscular Atrophy: DNA Preparation from Dried Blood Spot and DNA Polymerase Selection in PCR.
Muscular Diseases
Distal myopathy with cachexia: an unrecognised phenotype caused by dominantly-inherited mitochondrial polymerase ? mutations.
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy.
Skeletal muscle mitochondria from AZT-treated rats have a diminished response to chronic electrical stimulation.
Muscular Dystrophies
Decrease of lactoferrin concentration in the tears of myotonic muscular dystrophy patients.
ENZYME STUDIES IN MUSCULAR DYSTROPHY. IV. ACID DEOXYRIBONUCLEASE IN NUTRITIONAL AND HEREDITARY MUSCULAR DYSTROPHY.
ENZYME STUDIES IN MUSCULAR DYSTROPHY. VI. CATHEPSIN AND ACID DEOXYRIBONUCLEASE ACTIVITIES DURING THE PROGRESSION OF HEREDITARY MUSCULAR DYSTROPHY IN THE CHICKEN.
Successful treatment of atelectasis with Dornase alpha in a patient with congenital muscular dystrophy.
Mycoses
99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections.
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin.
Extracellular DNA: The tip of root defenses
Extracellular DNA: the tip of root defenses?
Regulation of fungal infection by a combination of amphotericin B and peptide 2, a lactoferrin peptide that activates neutrophils.
Mycosis Fungoides
Treatment of refractory peripheral T-cell lymphoma with denileukin diftitox (ONTAK).
Myelodysplastic Syndromes
The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34+CD123+ cells from acute myeloid leukemia/myelodysplastic syndrome patients and healthy donors.
[Granule protein contents of polymorphonuclear leucocytes and serum in 30 cases of myelodysplastic syndromes]
Myeloproliferative Disorders
Intracellular lysozyme and lactoferrin in myeloproliferative disorders.
Lactoferrin in the myeloproliferative disorders: a search for granulopoietic regulator defects.
Quantitation of RNA-dependent platelet DNA polymerase in patients with myeloproliferative disorders.
Myocardial Infarction
Acute DNase1 treatment improves left ventricular remodeling after myocardial infarction by disruption of free chromatin.
Association of deoxyribonuclease I genetic polymorphisms with myocardial infarction in Han Chinese.
Association of Gln222Arg polymorphism in the deoxyribonuclease I (DNase I) gene with myocardial infarction in Japanese patients.
Clinical applications of DNase I, a genetic marker already used for forensic identification.
Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction.
Deoxyribonuclease I: exploring the hidden side of myocardial infarction.
Development of a sensitive enzyme-linked immunosorbent assay for measurement of DNase I in human serum.
Diagnostic use of serum deoxyribonuclease I activity as a novel early-phase marker in acute myocardial infarction.
Frequency of a single nucleotide (A2317G) and 56-bp variable number of tandem repeat polymorphisms within the deoxyribonuclease I gene in five ethnic populations.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Homogeneous Immunochemical Assay on the Lateral Flow Strip for Measurement of DNase I Activity.
Hypoxia induces upregulation of the deoxyribonuclease I gene in the human pancreatic cancer cell line QGP-1.
Levels of serum deoxyribonuclease I activity on admission in patients with acute myocardial infarction can be useful in predicting left ventricular enlargement due to remodeling.
Matrix metalloproteinases and membrane damage markers in sera of patients with acute myocardial infarction.
Rapid measurement of deoxyribonuclease I activity with the use of microchip electrophoresis based on DNA degradation.
Serum deoxyribonuclease I activity can be a useful diagnostic marker for the early diagnosis of unstable angina pectoris or non-ST-segment elevation myocardial infarction.
Serum deoxyribonuclease I activity can be used as a novel marker of transient myocardial ischaemia: results in vasospastic angina pectoris induced by provocation test.
Serum deoxyribonuclease I activity can be used as a sensitive marker for detection of transient myocardial ischaemia induced by percutaneous coronary intervention.
Serum deoxyribonuclease I can be used as a useful marker for diagnosis of death due to ischemic heart disease.
Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury.
Two deoxyribonuclease I gene polymorphisms and correlation between genotype and its activity in Japanese population.
[Nucleic acid metabolism in the myocardium and their content in the blood in experimental myocardial infarct]
Myocardial Ischemia
Clinical applications of DNase I, a genetic marker already used for forensic identification.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Lactoferrin is a novel predictor of fatal ischemic heart disease in diabetes mellitus type 2: long-term follow-up of the HUNT 1 study.
Serum deoxyribonuclease I activity can be a useful diagnostic marker for the early diagnosis of unstable angina pectoris or non-ST-segment elevation myocardial infarction.
Serum deoxyribonuclease I can be used as a useful marker for diagnosis of death due to ischemic heart disease.
Myocarditis
Back Cover: Eur. J. Immunol. 8'16.
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin.
Diphtheria.
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Myoepithelioma
Myoepitheliomas and myoepithelial adenomas of salivary gland origin. Immunohistochemical evaluation of filament proteins, S-100 alpha and beta, glial fibrillary acidic proteins, neuron-specific enolase, and lactoferrin.
Myopia
Oral Bovine Milk Lactoferrin Administration Suppressed Myopia Development through Matrix Metalloproteinase 2 in a Mouse Model.
Myotonic Dystrophy
Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure.
Narcolepsy
Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function.
GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy.
Increased ?-haemolytic group A streptococcal M6 serotype and streptodornase B-specific cellular immune responses in Swedish narcolepsy cases.
Nasal Polyps
Lactoferrin inhibits the growth of nasal polyp fibroblasts.
Nasopharyngeal Carcinoma
Antibody against Epstein-Barr virus DNA polymerase activity in sera of patients with nasopharyngeal carcinoma.
c-myc gene inactivation during induction of nasopharyngeal carcinoma cells with retinoic acid.
Demonstration of a stimulatory protein for virus-specified DNA polymerase in phorbol ester-treated Epstein-Barr virus-carrying cells.
Demonstration of Epstein-Barr virus-specific DNA polymerase in chemically induced Raji cells and its antibody in serum from patients with nasopharyngeal carcinoma.
Diagnosis of nasopharyngeal carcinoma by means of recombinant Epstein-Barr virus proteins.
Expression of the Epstein-Barr virus DNA polymerase in Escherichia coli for use as antigen for the diagnosis of nasopharyngeal carcinoma.
Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.
High-level expression of the Epstein-Barr virus alkaline deoxyribonuclease using a recombinant baculovirus: application to the diagnosis of nasopharyngeal carcinoma.
Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice.
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Purified recombinant EBV desoxyribonuclease in serological diagnosis of nasopharyngeal carcinoma.
Serological Responses of Patients with Nasopharyngeal Carcinoma to an N-Terminal Epstein-Barr Virus DNA Polymerase Protein Expressed in Prokaryotic Cells.
Use of bacterially-expressed antigen for detection of antibodies to the EBV-specific deoxyribonuclease in sera from patients with nasopharyngeal carcinoma.
[The usefulness of serum antibody to Epstein-Barr virus-specific DNAase (EDAb) in early detection of nasopharyngeal carcinoma]
Nasopharyngitis
Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.
Neonatal Sepsis
Can lactoferrin prevent neonatal sepsis and necrotizing enterocolitis?
Clinical Benefits of Lactoferrin for Infants and Children.
Considerations in the pharmacologic treatment and prevention of neonatal sepsis.
Development and clinical evaluation of immunoluminometric assays for lactoferrin and elastase-alpha 1-proteinase inhibitor complexes in body fluids with special references to bronchoalveolar lavage and neonatal sepsis.
Effects of lactoferrin on neonatal pathogens and Bifidobacterium breve in human breast milk.
Enteral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
Human recombinant lactoferrin acts synergistically with antimicrobials commonly used in neonatal practice against coagulase-negative staphylococci and Candida albicans causing neonatal sepsis.
Immunomodulation to Prevent or Treat Neonatal Sepsis: Past, Present, and Future.
Immunotherapy in neonatal sepsis: advances in treatment and prophylaxis.
Is Mother's Own Milk Lactoferrin Intake Associated with Reduced Neonatal Sepsis, Necrotizing Enterocolitis, and Death?
Lactoferrin and Neonatology- Role in neonatal sepsis and necrotizing enterocolitis: Present, past and future.
Lactoferrin for prevention of neonatal sepsis.
Lactoferrin Metal Saturation-Which Form Is the Best for Neonatal Nutrition?
Lactoferrin Reduces Necrotizing Enterocolitis Severity by Upregulating Intestinal Epithelial Proliferation.
NEW POSSIBILITIES OF PREVENTION OF INFECTION IN THE NEWBORN.
Oral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Redox therapy in neonatal sepsis: reasons, targets, strategy, and agents.
Neoplasm Metastasis
A Point Mutation in DNA Polymerase ? (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer.
AAV-mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine.
Bovine lactoferrin and Lactoferricin inhibit tumor metastasis in mice.
Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice.
Bovine lactoferrin inhibits tumor-induced angiogenesis.
Cd11b(+) myeloid cells support hepatic metastasis through down-regulation of angiopoietin-like 7 in cancer cells.
Correlation between HPV status at T and N sites of oropharyngeal squamous cell carcinomas.
Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.
Effects of CRM197, a specific inhibitor of HB-EGF, in oral cancer.
Effects of serine protease and deoxyribonuclease on intravascular tumor cell arrest in rat blood-borne lung metastasis.
Endogenous PAD4 in Breast Cancer Cells Mediates Cancer Extracellular Chromatin Network Formation and Promotes Lung Metastasis.
Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis.
Extracellular DNA: A Bridge to Cancer.
Human lactoferrin inhibits growth of solid tumors and development of experimental metastases in mice.
IL-8 mediates a positive loop connecting increased neutrophil extracellular traps (NETs) and colorectal cancer liver metastasis.
Immunoexpression of lactoferrin in bone metastases and corresponding primary carcinomas.
Increased neutrophil extracellular traps promote metastasis potential of hepatocellular carcinoma via provoking tumorous inflammatory response.
Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I.
Inhibitory effects of bovine lactoferrin on colon carcinoma 26 lung metastasis in mice.
Intravital Förster resonance energy transfer imaging reveals osteopontin-mediated polymorphonuclear leukocyte activation by tumor cell emboli.
Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice.
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Low density neutrophils (LDN) in postoperative abdominal cavity assist the peritoneal recurrence through the production of neutrophil extracellular traps (NETs).
Orally administered bovine lactoferrin induces caspase-1 and interleukin-18 in the mouse intestinal mucosa: a possible explanation for inhibition of carcinogenesis and metastasis.
Orally administered bovine lactoferrin systemically inhibits VEGF(165)-mediated angiogenesis in the rat.
Ozone-primed neutrophils promote early steps of tumour cell metastasis to lungs by enhancing their NET production.
Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of ESCC.
Prevention of carcinogenesis and cancer metastasis by bovine lactoferrin.
Prevention of colon carcinogenesis and carcinoma metastasis by orally administered bovine lactoferrin in animals.
Quantitative estimation of tumor metastasis by measurement of DNA polymerase activity.
Regulation of PKB/Akt-pathway in the chemopreventive effect of lactoferrin against diethylnitrosamine-induced hepatocarcinogenesis in rats.
Role of Pentacyclic Triterpenoids in Chemoprevention and Anticancer Treatment: An Overview on Targets and Underling Mechanisms.
Serine protease-induced enhancement of blood-borne metastasis of rat ascites tumour cells and its prevention with deoxyribonuclease.
Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models.
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.
The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells.
Tumoricidal Activity of RNase A and DNase I.
[Inhibition of Invasive Properties of Murine Melanoma by Bovine Pancreatic DNase I In Vitro and In Vivo].
Neoplasm, Residual
Clinical Activity and Tolerability of SL-401 (Tagraxofusp): Recombinant Diphtheria Toxin and Interleukin-3 in Hematologic Malignancies.
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.
Neoplasms
"Iron-saturated" bovine lactoferrin improves the chemotherapeutic effects of tamoxifen in the treatment of basal-like breast cancer in mice.
'Iron-saturated' lactoferrin is a potent natural adjuvant for augmenting cancer chemotherapy.
3-Cyclic amine derivatives of rifamycin: strong inhibitors of the DNA polymerase activity of RNA tumor viruses.
67Ga-transferrin and 67Ga-lactoferrin binding to tumor cells: specific versus nonspecific glycoprotein-cell interaction.
A 1-Mb PAC contig spanning the common eliminated region 1 (CER1) in microcell hybrid-derived SCID tumors.
A binding free energy decomposition approach for accurate calculations of the fidelity of DNA polymerases.
A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression.
A combination of LightOn gene expression system and tumor microenvironment-responsive nanoparticle delivery system for targeted breast cancer therapy.
A Common Cancer-Associated DNA Polymerase {varepsilon} Mutation Causes an Exceptionally Strong Mutator Phenotype, Indicating Fidelity Defects Distinct from Loss of Proofreading.
A comparison of the effects of daunomycin and adriamycin on various DNA polymerases.
A comprehensive experiment for molecular biology: Determination of single nucleotide polymorphism in human REV3 gene using PCR-RFLP.
A deoxyribonuclease from mammary tumours of C3H mice preferentially hydrolysing heat-denatured DNA.
A DNA polymerase from Ehrlich ascites tumor cells with preference for native DNA.
A mutation in POLE predisposing to a multi-tumour phenotype.
A new medium-term rat colon bioassay applying neoplastic lesions as endpoints for detection of carcinogenesis modifiers-validation with known modifiers.
A novel 'smart' PNIPAM-based copolymer for breast cancer targeted therapy: Synthesis, and characterization of dual pH/temperature-responsive lactoferrin-targeted PNIPAM-co-AA.
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid.
A novel POLH mutation causes XP-V disease and XP-V tumor proneness may involve imbalance of numerous DNA polymerases.
A panoply of errors: polymerase proofreading domain mutations in cancer.
A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer.
A Phase I study of the oral antimetabolite, CS-682, administered once daily 5 days per week in patients with refractory solid tumor malignancies.
A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response.
A polymer library approach to suicide gene therapy for cancer.
A potent anti-HB-EGF monoclonal antibody inhibits cancer cell proliferation and multiple angiogenic activities of HB-EGF.
A recombinant cytotoxic chimera based on mammalian deoxyribonuclease-I.
A recurrent cancer-associated substitution in DNA polymerase ? produces a hyperactive enzyme.
A role for MAP kinase in the antitumor activity of a nucleoside analog.
A role for milk proteins and their peptides in cancer prevention.
A site of action for zinc in neoplastic tissue.
A Small-Molecule Inhibitor of Human DNA Polymerase ? Potentiates the Effects of Cisplatin in Tumor Cells.
A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer.
A target-specific oral formulation of Doxorubicin-protein nanoparticles: efficacy and safety in hepatocellular cancer.
A targetable HB-EGF-CITED4 axis controls oncogenesis in lung cancer.
AAV-mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response.
Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions.
Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
Acinic cell carcinoma of the palate: case report and immunohistochemical observation.
Actin content and actin polymerization in hepatoma Morris 5123 tumor bearing rats after treatment with cysteine protease inhibitor and vitamin E.
Actin in the acrosome of the spermatozoa of the crab, Cancer pagurus L. (Decapoda, Crustacea).
Actin polymerisation in Walker 256 carcinoma cells from solid or ascitic tumours.
Actin-resistant DNAse I Expression From Oncolytic Adenovirus Enadenotucirev Enhances Its Intratumoral Spread and Reduces Tumor Growth.
Activated and non-activated PAMAM dendrimers for gene delivery in vitro and in vivo.
Activation of macrophages by lactoferrin: secretion of TNF-alpha, IL-8 and NO.
Activation of STAT 5-cyclin D1 pathway in chewing tobacco mediated oral squamous cell carcinoma.
Activities of DNA polymerase in human urogenital tumors.
Activities of various enzymes of pyrimidine nucleotide and DNA syntheses in normal and neoplastic human tissues.
Activity of Species-specific Antibiotics Against Crohn's Disease-Associated Adherent-invasive Escherichia coli.
Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of the gut.
Adaptive and inflammatory immune responses in patients infected with strains of Vibrio parahaemolyticus.
Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers.
Adenomatoid odontogenic tumour: immunohistochemical demonstration of transferrin, ferritin and alpha-one-antitrypsin.
Adenovirus type 12 tumor antigen. I. Separation from DNA polymerase alpha and immunoprecipitation of tumor-antigen polypeptides.
Adenovirus-Mediated CRM197 Sensitizes Human Glioma Cells to Gemcitabine by the Mitochondrial Pathway.
Aerosolized BC-819 inhibits primary but not secondary lung cancer growth.
Age-prevalence of Otarine Herpesvirus-1, a tumor-associated virus, and possibility of its sexual transmission in California sea lions.
Age-related faecal calprotectin, lactoferrin and tumour M2-PK concentrations in healthy volunteers.
Airway inflammation in nonobstructive and obstructive chronic bronchitis with chronic haemophilus influenzae airway infection. Comparison with noninfected patients with chronic obstructive pulmonary disease.
Albumin fusion at the N-terminus or C-terminus of human lactoferrin leads to improved pharmacokinetics and anti-proliferative effects on cancer cell lines.
Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.
Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.
Alterations in chromatin structure associated with glucocorticoid-induced expression of endogenous mouse mammary tumor virus genes.
Altered deoxyribonuclease activity in cancer cells and its role in non toxic adjuvant cancer therapy with mixed vitamins C and K3.
Altered regulation of MHC class I genes in different tumor cell lines is reflected by distinct sets of DNase I hypersensitive sites.
Amplification and analysis of DNA flanking known sequences of a novel herpesvirus from green turtles with fibropapilloma Brief report.
An Anti-PSMA Bivalent Immunotoxin Exhibits Specificity and Efficacy for Prostate Cancer Imaging and Therapy.
An attempt to correlate RNA-templated DNA polymerase activity with virus-like particles in human milk: murine mammary tumor virus (MuMTV) as a model system.
An inhibitor of DNA polymerase which appears after inoculation of BALB-c mice with syngeneic tumors.
An intronic alternative promoter of the human lactoferrin gene is activated by Ets.
Analysis of key molecules of the innate immune system in mammary epithelial cells isolated from marker-assisted and conventionally selected cattle.
Analysis of tumor-infiltrating gamma delta T cells in rectal cancer.
Angiosarcoma Arising from the Tongue of an 11-Year-Old Girl with Xeroderma Pigmentosum.
Anti-cancer binary system activated by bacteriophage HK022 integrase.
Anti-tumor Effect of Intravenous Administration of CRM197 for Triple-negative Breast Cancer Therapy.
Anti-tumor effect of orally administered spinach glycolipid fraction on implanted cancer cells, colon-26, in mice.
Antibody to lactate dehydrogenase. V. Use as a carrier for introducing diphtheria toxin into mouse tumor cells.
Anticancer Activity of Bacterial Proteins and Peptides.
Anticancer activity of lactoferrin isolated from caprine colostrum on human cancer cell lines
Anticancer Effect of Enterocin A-Colicin E1 Fusion Peptide on the Gastric Cancer Cell.
Anticancer effects of lactoferrin: underlying mechanisms and future trends in cancer therapy.
Antimicrobial and immunoregulatory functions of lactoferrin and its potential therapeutic application.
Antimicrobial peptides: the ancient arm of the human immune system.
Antitumor activity of DAB389IL-2 fusion toxin in mycosis fungoides.
Antitumor and biological effects of black pine (pinus nigra) pollen nuclease.
Antitumor and genotoxic effects of lactoferrin in Walker-256 tumor-bearing rats.
Antitumor Effects of Systemic DNAse I and Proteases in an In Vivo Model.
Antitumor efficacy of Lf modified daunorubicin plus honokiol liposomes in treatment of brain glioma.
Antitumour activity and specificity as a function of substitutions in the lipophilic sector of helical lactoferrin-derived peptide.
Aphidicolin Chemistry of the Deep-Sea-Derived Fungus Botryotinia fuckeliana MCCC 3A00494.
Aphidicolin inhibits cell proliferation via the p53-GADD45? pathway in AtT-20 cells.
Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Apoptotic effects of bovine apo-lactoferrin on HeLa tumor cells.
Application of fusogenic liposomes containing fragment A of diphtheria toxin to cancer therapy.
Association between birt hogg dube syndrome and cancer predisposition.
Association of enterotoxigenic Bacteroides fragilis infection with inflammatory diarrhea.
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.
Attempts to Detect Agrobacterium tumefaciens DNA in Crown-Gall Tumor Tissue.
Attenuated diphtheria toxin mediates siRNA delivery.
Author Correction: Doxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice.
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die.
Autoschizis: a novel cell death.
Bacteria and their toxins tamed for immunotherapy.
Bacterial tRNase-Based Gene Therapy with Poly(?-Amino Ester) Nanoparticles for Suppressing Melanoma Tumor Growth and Relapse.
Bacterial-lipopolysaccharide-induced release of lactoferrin from human polymorphonuclear leukocytes: role of monocyte-derived tumor necrosis factor alpha.
Bacteriocin production by mucosal bacteria in current and previous colorectal neoplasia.
Basaloid-squamous carcinoma of the esophagus with marked deposition of basement membrane substance.
Bax is a transcriptional target and mediator of c-myc-induced apoptosis.
BC-819, a plasmid comprising the H19 gene regulatory sequences and diphtheria toxin A, for the potential targeted therapy of cancers.
Binding of Lactoferrin to IGBP1 Triggers Apoptosis in a Lung Adenocarcinoma Cell Line.
Bioactive Membrane Immobilized with Lactoferrin for Modulation of Bone Regeneration and Inflammation.
Bioactive proteins in breast milk.
Biochemical and immunological characterization of Suncus murinus mammary tumor virus DNA polymerase.
Biological and Therapeutic Relevance of Nonreplicative DNA Polymerases to Cancer.
Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas.
Biological markers in nasal secretions.
Biomimetic recognition strategy for efficient capture and release of circulating tumor cells.
Bovine lactoferrin and Lactoferricin inhibit tumor metastasis in mice.
Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice.
Bovine lactoferrin and lactoferrin peptides affect endometrial and cervical cancer cell lines.
Bovine lactoferrin decreases histopathological changes in the liver and regulates cytokine production by splenocytes of obstructive jaundiced rats.
Bovine lactoferrin inhibits tumor-induced angiogenesis.
Bovine lactoferrin protects RSC96 Schwann cells from tumor necrosis factor-alpha-induced growth arrest via extracellular-signal-regulated kinase 1/2.
Bronchial carcinoid tumor mimicking acinic cell tumor.
Calcitonin gene-related peptide (CGRP) activates human neutrophils--inhibition by chemotactic peptide antagonist BOC-MLP.
Cancer immunity after treatment of Ehrlich tumor with diphtheria toxin.
Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies.
Cancer prevention by bovine lactoferrin: from animal studies to human trial.
Cancer progression mediated by horizontal gene transfer in an in vivo model.
Cancer, pancreatitis, and the detection of the isoenzymes of DNAase, RNAase and amylase.
Catechin conjugated with Fatty Acid inhibits DNA polymerase and angiogenesis.
CD123 as a Biomarker in Hematolymphoid Malignancies: Principles of Detection and Targeted Therapies.
Cell kinetic-directed sequential chemotherapy with cyclophosphamide and adriamycin in T1699 mammary tumors.
Cell kinetics in ovarian cancer. Relationship to clinicopathologic features, responsiveness to chemotherapy, and survival.
Cell kinetics in vivo and in vitro for C3H/He spontaneous mammary tumors.
Cell proliferation detected by DNA polymerase alpha in acute leukemias.
Cell proliferation in colorectal tumor progression: an immunohistochemical approach to intermediate biomarkers.
Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: potential for cytotoxic gene therapy.
Cell-specific expression of the diphtheria toxin A-chain coding sequence induces cancer cell suicide.
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
Changes in chromosomal proteins in colon cancer: the complexity and DNA-binding properties of tumor-associated proteins and evidence for their association with the malignant state in human colonic epithelium.
Changes in the topological expression of markers of differentiation and apoptosis in defined stages of human cervical dysplasia and carcinoma.
Characteristic variations of serum alkaline DNase activity in relation to response to therapy and tumor prognosis in human lung cancer.
Characteristics of DNA repair induced by DNA polymerase ? in hepatoma cells after ?-ray irradiation.
Characterization and sequence-specific binding to mouse mammary tumor virus DNA of purified activated human glucocorticoid receptor.
Characterization of an RNA-directed DNA-polymerase from a cell line derived from a radiation-induced lymphoma in mice.
Characterization of cells obtained by mechanical and enzymatic means from human melanoma, sarcoma, and lung tumors.
Characterization of mouse mammary tumor viruses from primary tumor cell cultures. II. Biochemical and biophysical studies.
Characterization of the interaction of the human mineralocorticosteroid receptor with hormone response elements.
Characterization of virus-like particles released from the hamster cell line CHO-K1 after treatment with 5-bromodeoxyuridine.
Chemical carcinogen-induced transplantable fibrosarcomas in histocompatible chickens. I. Incidence of tumor induction in normal and bursectomized chickens.
Children's brain tumour cells produce RNA particles with incomplete retrovirus characteristics.
Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs.
Chromatin solubilization in rapidly growing hepatomas.
Chromatin structure and DNase I hypersensitivity in the transcriptionally active and inactive porcine tumor necrosis factor gene locus.
Chromatin structure of the murine c-myc locus: implications for the regulation of normal and chromosomally translocated genes.
Chromatin structure of the promoter region of the human c-K-ras gene.
Class II transactivator-mediated regulation of major histocompatibility complex class II antigen expression is important for hematopoietic progenitor cell suppression by chemokines and iron-binding proteins.
Clinical Activity and Tolerability of SL-401 (Tagraxofusp): Recombinant Diphtheria Toxin and Interleukin-3 in Hematologic Malignancies.
Clinical characteristics and treatment outcome of oropharyngeal squamous cell carcinoma in an endemic betel quid region.
Clinical Experience of Treatment of Metastatic Melanoma and Solid Tumours Adopting a Derivative of Diphtheria Toxin: Cross-reacting Material 197.
Clinical features and prognostic factors in Covid-19: A prospective cohort study.
Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
Co-assembled Ca2+ Alginate-Sulfate Nanoparticles for Intracellular Plasmid DNA Delivery.
Cocoon-like self-degradable DNA nanoclew for anticancer drug delivery.
Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutations.
Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation.
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.
Combined prokaryotic-eukaryotic delivery and expression of therapeutic factors through a primed autocatalytic positive-feedback loop.
Comparative two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) of human milk to identify dysregulated proteins in breast cancer.
Comparison of the intoxication pathways of tumor necrosis factor and diphtheria toxin.
Composite tumor with papillary adenocarcinoma and squamous cell carcinoma of the esophagus: report of a case.
Conclusive Evidence for OCT4 Transcription in Human Cancer Cell Lines: Possible Role of a Small OCT4-Positive Cancer Cell Population.
Conjugation Magnetic PAEEP-PLLA Nanoparticles with Lactoferrin as a Specific Targeting MRI Contrast Agent for Detection of Brain Glioma in Rats.
Conservation of structure and function of DNA replication protein A in the trypanosomatid Crithidia fasciculata.
Considering the cancer consequences of altered DNA polymerase function.
Consistent downregulation of human lactoferrin gene, in the common eliminated region 1 on 3p21.3, following tumor growth in severe combined immunodeficient (SCID) mice.
Constitutive overexpression of DNA binding activity to the distal CCAAT box of human thymidine kinase promoter in human tumor cell lines.
Continuing rise in oropharyngeal cancer in a high HPV prevalence area: A Danish population-based study from 2011 to 2014.
Control of Ehrlich cell division by zinc.
Correlation between spontaneous oscillations of cytosolic free Ca2+ and tumor necrosis factor-induced degranulation in adherent human neutrophils.
Correlations between eyelid tumors and tear lipocalin, lysozyme and lactoferrin concentrations in postmenopausal women.
Corrigendum to "LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumour targeting and NIR, MRI and CT imaging" [Biomaterials 71C (2015) 84-99].
Corynebacterium diphtheriae: Diphtheria Toxin, the tox Operon, and Its Regulation by Fe2+ Activation of apo-DtxR.
Covalently linked RNA-DNA molecule as initial product of RNA tumour virus DNA polymerase.
CRM197 (nontoxic diphtheria toxin): effects on advanced cancer patients.
CRM197 in Combination With shRNA Interference of VCAM-1 Displays Enhanced Inhibitory Effects on Human Glioblastoma Cells.
Cross-reacting material 197, a heparin-binding EGF-like growth factor inhibitor, reverses the chemoresistance in human cisplatin-resistant ovarian cancer.
Cryptosporidiosis stimulates an inflammatory intestinal response in malnourished Haitian children.
Crystal structure of human ADP-ribose transferase ARTD15/PARP16 reveals a novel putative regulatory domain.
Curcumin suppresses gastric tumor cell growth via ROS-mediated DNA polymerase ? depletion disrupting cellular bioenergetics.
Cystatin C and lactoferrin concentrations in biological fluids as possible prognostic factors in eye tumor development.
Cytotoxic properties of DAB486EGF and DAB389EGF, epidermal growth factor (EGF) receptor-targeted fusion toxins.
Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt(II) chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.
Defining the mutation signatures of DNA polymerase ? in cancer genomes.
Deletions and insertions in the p53 tumor suppressor gene in human cancers: confirmation of the DNA polymerase slippage/misalignment model.
Demonstration of lactoferrin in tumor tissue from two patients with positive gallium scans.
Deoxyribonuclease activity and circulating DNA concentration in blood plasma of patients with prostate tumors.
Deoxyribonuclease activity in biological fluids of healthy donors and cancer patients.
Deoxyribonuclease activity in normal and cancer urines of humans.
Deoxyribonuclease I (DNAse I). A novel approach for targeted cancer therapy.
Deoxyribonuclease I serum activity in pancreatic cancer.
Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice.
Deoxyribonucleic acid of Cancer pagurus. II. Template activity for a DNA-dependent DNA polymerase of eukaryotic cells.
Design of a Cytotoxic Neuroblastoma-Targeting Agent Using an Enzyme Acting on Polysialic Acid Fused to a Toxin.
Destruction of Neutrophil Extracellular Traps Promotes the Apoptosis and Inhibits the Invasion of Gastric Cancer Cells by Regulating the Expression of Bcl-2, Bax and NF-?B.
Detection in human ovary and prostate tumors of DNA polymerase activity that copies poly(2'-O-methylcytidylate) . oligodeoxyguanylate.
Detection of exon polymorphisms in the human lactoferrin gene.
Detection of hTERT protein by flow cytometry.
Detection of mutation(s) or polymorphic loci in the genome of experimental animal and human cancer tissues by RAPD/AP-PCR depend on DNA polymerase.
Detection of proliferative cells in dysplasia, carcinoma in situ, and invasive carcinoma of the uterine cervix by monoclonal antibody against DNA polymerase alpha.
Detection of reverse transcriptase activity in human cells.
Detection of viral DNA polymerase activity in salmon tumour tissue induced by herpes virus, Oncorhynchus masou virus.
Determination of faecal inflammatory marker concentration as a noninvasive method of evaluation of pathological activity in children with inflammatory bowel diseases.
Development and characterization of lactoferrin nanoliposome: cellular uptake and stability.
Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies.
Development of a nonintegrating Rev-dependent lentiviral vector carrying diphtheria toxin A chain and human TRAF6 to target HIV reservoirs.
Development of a radioimmunoassay for human deoxyribonuclease I.
Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for a broad spectrum of solid tumors mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P4 and IGF2-P3 regulatory sequences.
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences.
Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion.
Diagnostic Value of Serum DNASE1L3 in Hepatitis B Virus-Related Hepatocellular Carcinoma.
Dietary Inclusion of Colicin E1 Is Effective in Preventing Postweaning Diarrhea Caused by F18-Positive Escherichia coli in Pigs.
Difference in DNA polymerase activity in lymphoid tumor between avian lymphoid leukosis and Marek's disease.
Differential DNase I sensitivity of the two complementary nucleosomal DNA strands in cycloheximide-treated Ehrlich ascites tumor cells.
Differential effect of collaterally sensitive antimetabolites on P388 murine leukemia sensitive and resistant to adriamycin in vitro.
Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice.
Differential expression of immune response genes associated with subclinical mastitis in dairy buffaloes.
Diphtheria fusion protein therapy of chemoresistant malignancies.
Diphtheria toxin conjugate therapy of cancer.
Diphtheria toxin effects on brain-tumor xenografts. Implications for protein-based brain-tumor chemotherapy.
Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.
Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals.
Diphtheria toxin treatment of human advanced cancer.
Discrimination and evaluation of lactoferrin and delta-lactoferrin gene expression levels in cancer cells and under inflammatory stimuli using TaqMan real-time PCR.
Dissecting the Functional Significance of DNA Polymerase Mutations in Cancer.
Distinct roles of RAD52 and POLQ in chromosomal break repair and replication stress response.
Distribution of deoxyribonuclease activities in the subcellular fractions of mammary tumors of C3H mice.
Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer.
DNA damage tolerance pathway involving DNA polymerase ? and the tumor suppressor p53 regulates DNA replication fork progression.
DNA polymerase ? (POLQ), double-strand break repair, and cancer.
DNA polymerase ? as a potential biomarker of chemoradiation resistance and poor prognosis for cervical cancer.
DNA Polymerase ? Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity.
DNA Polymerase ? Increases Mutational Rates in Mitochondrial DNA.
DNA polymerase ? modulates replication fork progression and DNA damage responses in platinum-treated human cells.
DNA polymerase ? mutational signatures are found in a variety of different types of cancer.
DNA Polymerase ?: A Cancer Drug Target with Reverse Transcriptase Activity.
DNA polymerase activities in fractionated Walker-256 tumor cell nuclei.
DNA polymerase activity associated with RNA tumor viruses.
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.
DNA polymerase and terminal deoxynucleotidyl transferase activity of normal and bacteria-free crown gall tumor tissue cultures of tobacco.
DNA polymerase in nuceoli isolated from Ehrlich ascites tumor cells.
DNA polymerase {epsilon} and ? exonuclease domain mutations in endometrial cancer.
DNA polymerases during tumor growth.
DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine.
DNA replication error-induced extinction of diploid yeast.
DNA synthesis in tumor-bearing rats.
DNase I hypersensitive sites in the 5' flanking region of the human plasminogen activator inhibitor type 2 (PAI-2) gene are associated with basal and tumor necrosis factor-alpha-induced transcription in monocytes.
DNase I inhibitions in tumors of different metastasizing capacities: a possible index of invasiveness.
DNAse I pre-treatment markedly enhances detection of nuclear cyclin-dependent kinase inhibitor p57Kip2 and BrdU double immunostaining in embryonic rat brain.
DNase I sensitivity of endogenous and exogenous proviral genome copies in M-MuLV-induced tumors of Mov-3 Mice.
DNASE1L3 arrests tumor angiogenesis by impairing the senescence-associated secretory phenotype in response to stress.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
DNASE1L3 as an indicator of favorable survival in hepatocellular carcinoma patients following resection.
DNase1L3 suppresses hepatocellular carcinoma growth via inhibiting complement autocrine effect.
Doxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice.
Drug action on ribonucleotide reductase.
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion.
DT390-triTMTP1, a novel fusion protein of diphtheria toxin with tandem repeat TMTP1 peptide, preferentially targets metastatic tumors.
Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer.
Dz13 induces a cytotoxic stress response with upregulation of E2F1 in tumor cells metastasizing to or from bone.
Early response in neonatal septicemia. The effect of Escherichia coli, Streptococcus agalactiae and tumor necrosis factor on the generation of lactoferrin.
Early response in septicemia in newborns and their mothers. Effect of Escherichia coli, Streptococcus agalactiae and tumor necrosis factor on lactoferrin release and the generation of tissue thromboplastin.
Effect of antibiotic treatment on inflammatory markers and lung function in cystic fibrosis patients with Pseudomonas cepacia.
Effect of auranofin on cytokine induced secretion of granule proteins from adherent human neutrophils in vitro.
Effect of cyclophosphamide on the pathophysiology of RIF-1 solid tumors.
Effect of cytokines and chemokines (TGF-beta, TNF-alpha, IL-6, IL-10, MCP-1, RANTES) gene polymorphisms in kidney recipients on posttransplantation outcome: influence of donor-recipient match.
Effect of deoxyribonuclease on adriamycin-polynucleotide complexes.
Effect of diphtheria toxin on lysosome activity in leukocytes and Ehrlich ascites tumor cells.
Effect of electroporation-mediated diphtheria toxin A expression on PSA positive human prostate xenograft tumors in SCID mice.
Effect of estrogen receptor ? binding on functional DNA methylation in breast cancer.
Effect of Heat Treatment on the Antitumor Activity of Lactoferrin in Human Colon Tumor (HT29) Model.
Effect of lactoferrin on taste and smell abnormalities induced by chemotherapy: a proteome analysis.
Effect of lactoferrin on the production of tumor necrosis factor-alpha and nitric oxide.
Effect of methylprednisolone on the cell kinetic response of C3H/HeJ mammary tumors to cyclophosphamide and adriamycin.
EFFECT OF PHLEOMYCIN ON DNA POLYMERASE OF TUMOR ORIGIN.
Effect of Recombinant Human Deoxyribonuclease on Oropharyngeal Secretions in Patients With Head-and-Neck Cancers Treated With Radiochemotherapy.
Effect of ribonuclease and deoxyribonuclease on incorporation of tritiated pyrimidine-nucleosides into ribonucleic acid and deoxyribonucleic acid in human cancer cells (HeLa) in culture.
Effect of short-term dietary intake of bovine lactoferrin on intestinal lymphocyte apoptosis in healthy mice.
Effect of surgical removal on the growth and kinetics of residual tumor.
Effects of BCL-2 overexpression on the sensitivity of MCF-7 breast cancer cells to ricin, diphtheria and Pseudomonas toxin and immunotoxins.
Effects of CRM197, a specific inhibitor of HB-EGF, in oral cancer.
Effects of Epstein-Barr Virus Infection on the Risk and Prognosis of Primary Laryngeal Squamous Cell Carcinoma: A Hospital-Based Case-Control Study in Taiwan.
Effects of essential oils from herbal plants and citrus fruits on DNA polymerase inhibitory, cancer cell growth inhibitory, antiallergic, and antioxidant activities.
Effects of human lactoferrin on NK cell cytotoxicity against haematopoietic and epithelial tumour cells.
Effects of iron-binding proteins on in vitro uptake of 67Ga-citrate by tumor cells.
Effects of polyamines on DNA synthesis using various subcellular DNA polymerases extracted from normal rat liver, tumour-bearing rat liver, and tumour cells.
Effects of serine protease and deoxyribonuclease on intravascular tumor cell arrest in rat blood-borne lung metastasis.
Effects of Topical Thymoquinone in an Experimental Dry Eye Model
Effects of x-ray irradiation upon metabolism of desoxyribonucleic acid and desoxyribonuclease. II. In rat tumor.
Efficacy and safety of oral lactoferrin supplementation in combination with rHuEPO-beta for the treatment of anemia in advanced cancer patients undergoing chemotherapy: open-label, randomized controlled study.
Efficacy, safety and anticancer activity of protein nanoparticle-based delivery of doxorubicin through intravenous administration in rats.
Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma.
Elimination of proinflammatory cytokines in pediatric cardiac surgery: analysis of ultrafiltration method and filter type.
Emerging strategies for ErbB ligand-based targeted therapy for cancer.
EMT6 solid tumor growth, DNA synthesis and DNA polymerase activity.
Endogenous DNA polymerase of a transformation-defective rous sarcoma virus: characterization and comparison with the enzyme of the non-defective parent.
Endogenous PAD4 in Breast Cancer Cells Mediates Cancer Extracellular Chromatin Network Formation and Promotes Lung Metastasis.
Engineering a waste management enzyme to overcome cancer resistance to apoptosis: adding DNase1 to the anti-cancer toolbox.
Enhanced deoxyribonuclease activity in human transformed cells and in Bloom's syndrome cells.
Enhanced expression of DNA polymerase eta contributes to cisplatin resistance of ovarian cancer stem cells.
Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - a mammalian DNA polymerase inhibitor.
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells.
Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair.
Entry of diphtheria toxin into cells: possible existence of cellular factor(s) for entry of diphtheria toxin into cells was studied in somatic cell hybrids and hybrid toxins.
Enzymatic activity of endogenous telomerase associated with intact nuclei from human leukemia CEM cells.
Enzyme-induced aggregation and disaggregation of tumor cells via the cell surface glycocalyx in association with deoxyribonucleic acid.
Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis.
Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers.
Epithelial markers for paraffin-embedded human tissues. Immunohistochemistry with monoclonal antibodies against milk fat globule antigens.
Eradication of Human Ovarian Cancer Cells by Transgenic Expression of Recombinant DNASE1, DNASE1L3, DNASE2, and DFFB Controlled by EGFR Promoter: Novel Strategy for Targeted Therapy of Cancer.
Estrogen induced expansion of the growth fraction in receptor negative human breast cancer.
Evaluation of Antioxidant Intakes in Relation to Inflammatory Markers Expression Within the Normal Breast Tissue of Breast Cancer Patients.
Evaluation of Milk Colostrum Derived Lactoferrin of Sahiwal (Bos indicus) and Karan Fries (Cross-Bred) Cows for Its Anti-Cancerous Potential.
Evaluation of serum alkaline DNase activity in treatment monitoring of head and neck cancer patients.
Evolutionary dynamics and significance of multiple subclonal mutations in cancer.
Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics.
Explosive mutation accumulation triggered by heterozygous human Pol ? proofreading-deficiency is driven by suppression of mismatch repair.
Exposure to diethylstilbestrol during a critical developmental period of the mouse reproductive tract leads to persistent induction of two estrogen-regulated genes.
Expression and prognostic value of lactoferrin mRNA isoforms in human breast cancer.
Expression cloning of cDNAs that render cancer cells resistant to Pseudomonas and diphtheria toxin and immunotoxins.
Expression of active hormone and DNA-binding domains of the chicken progesterone receptor in E. coli.
Expression of diphtheria toxin A-chain in mature B-cells: a potential approach to therapy of B-lymphoid malignancy.
Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe.
Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis.
Extracellular DNA: A Bridge to Cancer.
Extremely well differentiated papillary adenocarcinoma of the lung with prominent cilia formation.
Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma.
Faecal parameters in the assessment of activity in inflammatory bowel disease.
Failure to detect naturally occurring serum inhibitors of hepatitis B virus deoxyribonucleic acid polymerase.
Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression.
Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc.
Fidelity levels of DNA polymerases in tumorigenic state cells and serially transplantable tumor cells.
Flow cytometric detection of proliferative cells in leukemias.
Foxp3 expression in macrophages associated with RENCA tumors in mice.
Fractionation of native and reconstituted chromatin by digesting with deoxyribonuclease ii.
Full length and delta lactoferrin display differential cell localization dynamics, but do not act as tumor markers or significantly affect the expression of other genes.
Functional Analysis of Cancer-Associated DNA Polymerase ? Variants in
Further studies on cytostatic activity of alkoxymethyl purine and pyrimidine acyclonucleosides.
Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP).
Gateways to clinical trials.
Gene delivery with optimized electroporation parameters shows potential for treatment of gliomas.
Gene expression of immunologically important factors in blood cells, milk cells, and mammary tissue of cows.
Gene expression profile of human colon cancer cells treated with cross-reacting material 197, a diphtheria toxin non-toxic mutant.
Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate.
Genetic and epigenetic inactivation of LTF gene at 3p21.3 in lung cancers.
Genomic analysis of the 55 kDa subunit of DNA polymerase epsilon in human intracranial neoplasms.
Genomic changes of the 55 kDa subunit of DNA polymerase epsilon in human breast cancer.
Germline and somatic polymerase ? and ? mutations define a new class of hypermutated colorectal and endometrial cancers.
Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells.
Growth differentiation factor-15 and lactoferrin immuno-expression in breast cancer: relationship with body iron-status and survival outcome.
Growth inhibition of cancer cells by co-transfection of diphtheria toxin A-chain gene plasmid with bovine leukemia virus-tax expression vector.
Growth kinetics of mammary tumor 13762 in rats previously cured by chemotherapy.
Growth suppression effects of recombinant adenovirus expressing human lactoferrin on cervical cancer in vitro and in vivo.
Hamartoma of the parotid gland: a case report with immunohistochemical and electron microscopic study.
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy.
Heparin-binding epidermal growth factor-like growth factor as a novel targeting molecule for cancer therapy.
Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition.
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.
High level expression in Escherichia coli of the DNA-binding domain of the glucocorticoid receptor in a functional form utilizing domain-specific cleavage of a fusion protein.
High mutational burden in colorectal carcinomas with monoallelic POLE mutations: absence of allelic loss and gene promoter methylation.
Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene.
Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer.
Hormone synergism in the in vitro production of the mouse mammary tumor virus.
HR-HPV E6/E7 mRNA In Situ Hybridization: Validation Against PCR, DNA In Situ Hybridization, and p16 Immunohistochemistry in 102 Samples of Cervical, Vulvar, Anal, and Head and Neck Neoplasia.
Human DNA polymerase ? harbors DNA end-trimming activity critical for DNA repair.
Human DNA polymerase beta mutations allowing efficient abasic site bypass.
Human endothelial cells regulate polymorphonuclear leukocyte degranulation.
Human lactoferrin inhibits growth of solid tumors and development of experimental metastases in mice.
Human pancreatic adenocarcinoma line Capan-1 in tissue culture and the nude mouse: morphologic, biologic, and biochemical characteristics.
Human Pol ?-dependent replication errors and the influence of mismatch repair on their correction.
Human POLB gene is mutated in high percentage of colorectal tumors.
Human tumor cells are selectively inhibited by colicins.
Human xeroderma pigmentosum group A protein interacts with human replication protein A and inhibits DNA replication.
Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth.
Hypersensitivity to cisplatin after hRev3 mRNA knockdown in head and neck squamous cell carcinoma cells.
Hypoxia influences linearly patterned programmed cell necrosis and tumor blood supply patterns formation in melanoma.
Hypoxia-regulated expression of attenuated diphtheria toxin A fused with hypoxia-inducible factor-1alpha oxygen-dependent degradation domain preferentially induces apoptosis of hypoxic cells in solid tumor.
Identification and characterization of synthetic viability with ERCC1 deficiency in response to interstrand crosslinks in lung cancer.
Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene.
Identification of cis-acting promoter elements important for expression of the mouse glycoprotein hormone alpha-subunit gene in thyrotropes.
Identification of diphtheria toxin R domain mutants with enhanced inhibitory activity against HB-EGF.
Identification of diphtheria toxin via screening as a potent cell cycle and p53-independent cytotoxin for human prostate cancer therapeutics.
Identification of the estrogen sensitive marker in human endometrial carcinoma RL95-2 cells.
Identification of the Flavobacterium johnsoniae cysteate-fatty acyl transferase required for capnine synthesis and for efficient gliding motility.
Identification of two enhancer elements downstream of the human c-myc gene.
Identification of unprecedented anticancer properties of high molecular weight biomacromolecular complex containing bovine lactoferrin (HMW-bLf).
Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer.
Immunocytochemistry of acinic cell carcinomas and mixed tumors of salivary glands.
Immunoexpression of lactoferrin in bone metastases and corresponding primary carcinomas.
Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak(®) on CD25(+) cells.
Immunohistochemical demonstration of lysozyme and lactoferrin in salivary pleomorphic adenomas.
Immunohistochemical investigation of lysozyme, lactoferrin, alpha 1-antitrypsin, alpha 1-antichymotrypsin and ferritin in parotid gland tumors.
Immunohistochemical markers in the identification of metastatic breast cancer.
Immunohistochemical study on sebaceous adenoma and sebaceous carcinoma arising in parotid gland.
Immunohistological study of the epithelial components of Warthin's tumor.
Immunohistology of anaplastic thyroid carcinoma. A study of 43 cases.
Immunolocalization of lactoferrin in cartilage-forming neoplasms.
Immunological Features with DNA Microsatellite Alterations in Patients with Colorectal Cancer.
Immunological status of patients subjected to cardiac surgery: effect of lactoferrin on proliferation and production of interleukin 6 and tumor necrosis factor alpha by peripheral blood mononuclear cells in vitro.
Immunomodulatory lactoferrin in the regulation of apoptosis modulatory proteins in cancer.
Immunomodulatory properties of human recombinant lactoferrin in mice: Implications for therapeutic use in humans.
Immunotherapy of experimental animal tumors with antitumor antibodies conjugated to diphtheria toxin or ricin.
Immunotoxins for targeted cancer therapy.
Immunotoxins: is there a clinical value?
Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis.
Implementation of Mass Cytometry for Immunoprofiling of Patients with Solid Tumors.
Improved Survival Associated with Local Tumor Response Following Multisite Radiotherapy and Pembrolizumab: Secondary Analysis of a Phase I Trial.
In situ lymphoid cells of mouse mammary tumors. I. Development and evaluation of a method for the separation of lymphoid cells from mouse mammary tumors.
In vivo antitumor effect of cationic liposomes containing diphtheria toxin A-chain gene on cells infected with bovine leukemia virus.
In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.
In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant.
In Vivo Tumor Therapy with Novel Immunotoxin Containing Programmed Cell Death Protein-1 and Diphtheria Toxin.
Incidence of colicinogenic strains among human Escherichia coli.
Increased circulating cytokines, cytokine antagonists, and E-selectin after intravenous administration of endotoxin in humans.
Increased uracil-DNA glycosylase, AP-DNA binding protein and deoxyribonuclease activities in tumor and SV40-transformed cell lines of human origin.
Increasing Cancer-Specific Gene Expression by Targeting Overexpressed ?5?1 Integrin and Upregulated Transcriptional Activity of NF-?B.
Incubation with DNase I inhibits tumor cell proliferation.
Induction of Epstein-Barr virus-associated DNA polymerase by 12-O-tetradecanoylphorbol-13-acetate. Purification and characterization.
Inflammatory markers in endometriosis: reduced peritoneal neutrophil response in minimal endometriosis.
Influences of diet and surgical trauma on serum alkaline DNase activity levels.
Inhalable Lactoferrin/Chondroitin-Functionalized Monoolein Nanocomposites for Localized Lung Cancer Targeting.
Inhalable multi-compartmental phospholipid enveloped lipid core nanocomposites for localized mTOR inhibitor/herbal combined therapy of lung carcinoma.
Inhibition of activities of DNA polymerase alpha, beta, gamma, and reverse transcriptase of L1210 cells by phosphonoacetic acid.
Inhibition of adrenocortical carcinoma by diphtheria toxin mutant CRM197.
Inhibition of azoxymethane initiated colon tumor and aberrant crypt foci development by bovine lactoferrin administration in F344 rats.
Inhibition of azoxymethane-initiated colon tumor by bovine lactoferrin administration in F344 rats.
Inhibition of DNA polymerase by sera of patients having leukemia and other reticuloendothelial malignancies.
Inhibition of growth of Erlich tumors in Swiss mice by diphtheria toxin.
Inhibition of mammalian and oncornavirus nucleic acid polymerase activities by alkoxybenzophenanthridine alkaloids.
Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I.
Inhibition of purified DNA polymerase of RNA tumor viruses by fluoranthene derivatives and analogues of tilorone hydrochloride.
Inhibition of tumor growth by recombinant adenovirus containing human lactoferrin through inducing tumor cell apoptosis in mice bearing EMT6 breast cancer.
Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation.
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response.
Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase ?.
Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation.
Inhibitory effects of ?-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation.
Inhibitory effects of bovine lactoferrin on colon carcinoma 26 lung metastasis in mice.
Inhibitory effects of bovine lactoferrin on intestinal polyposis in the Apc(Min) mouse.
Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth.
Inhibitory effects of diacylglyceride phospholipids on DNA polymerase and topoisomerase activities, and human cancer cell growth.
Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth.
Inhibitory effects of glycolipids fraction from spinach on mammalian DNA polymerase activity and human cancer cell proliferation.
Inhibitory effects of human lactoferrin on U14 cervical carcinoma through upregulation of the immune response.
Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation.
Inhibitory effects of myricetin on mammalian DNA polymerase, topoisomerase and human cancer cell proliferation.
Inhibitory effects of orally administrated liposomal bovine lactoferrin on the LPS-induced osteoclastogenesis.
Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.
Integrated Epigenetic Mapping of Human and Mouse Salivary Gene Regulation.
Interaction of androgen and glucocorticoid receptor DNA-binding domains with their response elements.
Interaction of Lactoferrin with Unsaturated Fatty Acids: In Vitro and In Vivo Study of Human Lactoferrin/Oleic Acid Complex Cytotoxicity.
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate.
Interleukin-6 is associated with tryptophan metabolism and signs of depression in individuals with carbohydrate malabsorption.
Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis.
Intratumor administration of fusogenic liposomes containing fragment A of diphtheria toxin suppresses tumor growth.
Investigation and comparison of the anti-tumor activities of lactoferrin, ?-lactalbumin, and ?-lactoglobulin in A549, HT29, HepG2, and MDA231-LM2 tumor models.
Iron and Its Role in Cancer Defense: A Double-Edged Sword.
Iron-binding proteins and 67Ga accumulation by tumor cells.
Iron-binding proteins in human colorectal adenomas and carcinomas: an immunocytochemical investigation.
Iron-binding proteins in thyroid tumours. An immunocytochemical study.
Irreversible Inhibition of DNA Polymerase ? by Small-Molecule Mimics of a DNA Lesion.
Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers?
Isolation and characterization of a neutral deoxyribonuclease from the testes of the crab Cancer pagurus.
Isolation of a lactoferrin cDNA clone and its expression in human breast cancer.
Isolation of DNA and DNA polymerase from MC 29 tumor virus.
Isolation of human DNA-unwinding elements as sites of DNA polymerase alpha/primase entry.
Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity.
Lactoferrin and C-reactive protein in response to cytostatic drugs with emphasis on methotrexate.
Lactoferrin and cancer disease prevention.
Lactoferrin and cancer in different cancer models.
Lactoferrin coated or conjugated nanomaterials as an active targeting approach in nanomedicine.
Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice.
Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.
Lactoferrin effects on the in vitro immune response in critically ill patients.
Lactoferrin enhances Fas expression and apoptosis in the colon mucosa of azoxymethane-treated rats.
Lactoferrin Exerts Antitumor Effects by Inhibiting Angiogenesis in a HT29 Human Colon Tumor Model.
Lactoferrin expression in breast cancer in relation to biologic properties of tumors and clinical features of disease.
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Lactoferrin in human tumours: immunohistochemical investigations during more than 25 years.
Lactoferrin in thyroid lesions: immunoreactivity in fine needle aspiration biopsy samples.
Lactoferrin induces growth arrest and nuclear accumulation of Smad-2 in HeLa cells.
Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
Lactoferrin inhibits growth of malignant tumors of the head and neck.
Lactoferrin is a natural inhibitor of plasminogen activation.
Lactoferrin is synthesized by activated microglia in the human substantia nigra and its synthesis by the human microglial CHME cell line is upregulated by tumor necrosis factor alpha or 1-methyl-4-phenylpyridinium treatment.
Lactoferrin is the major deoxyribonuclease of human milk.
Lactoferrin lowers serum interleukin 6 and tumor necrosis factor alpha levels in mice subjected to surgery.
Lactoferrin may inhibit the development of cancer via its immunostimulatory and immunomodulatory activities (Review).
Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat.
Lactoferrin protects against development of hepatitis caused by sensitization of Kupffer cells by lipopolysaccharide.
Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo.
Lactoferrin release and interleukin-1, interleukin-6, and tumor necrosis factor production by human polymorphonuclear cells stimulated by various lipopolysaccharides: relationship to growth inhibition of Candida albicans.
Lactoferrin, lysozyme, and beta 2-microglobulin levels in cerebrospinal fluid: differential indices of CNS inflammation.
Lactoferrin-Bearing Gold Nanocages for Gene Delivery in Prostate Cancer Cells in vitro.
Lactoferrin-dual drug nanoconjugate: Synergistic anti-tumor efficacy of docetaxel and the NF-?B inhibitor celastrol.
Lactoferrin-tethered betulinic acid nanoparticles promote rapid delivery and cell death in triple negative breast and laryngeal cancer cells.
Letter: Diphtheria toxin in cancer therapy.
Leukocyte populations and mRNA expression of inflammatory factors in quarter milk fractions at different somatic cell score levels in dairy cows.
Light-triggered, self-immolative nucleic Acid-drug nanostructures.
Lipopolysaccharide and lipoteichoic acid induce different immune responses in the bovine mammary gland.
Liposomal lactoferrin induced significant increase of the interferon-alpha (IFN-alpha) producibility in healthy volunteers.
Liposomalization of lactoferrin enhanced its anti-tumoral effects on melanoma cells.
LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.
Local and systemic response to intramammary lipopolysaccharide challenge during long-term manipulated plasma glucose and insulin concentrations in dairy cows.
Localization of lactoferrin and nonspecific cross-reacting antigen in human breast carcinomas. An immunohistochemical study using the avidin-biotin-peroxidase complex method.
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis.
Low malignant intraductal carcinoma on the hard palate: a variant of salivary duct carcinoma?
Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases.
Malignant oncocytoma of the parotid gland: a case report with an immunohistochemical and ultrastructural study.
Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.
Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
Mechanism of gallium-67 accumulation in tumors.
Mechanisms underlying aflatoxin-associated mutagenesis - Implications in carcinogenesis.
Mechanixm of Carcinogenesis By RNA Tumor Viruses, I. An RNA-Dependent DNA Polymerase In Murine Sarcoma Viruses.
Metabolism of pyrimidine nucleotides in various tissues and tumor cells from rodents.
Methylation and expression of the lactoferrin gene in human tissues and cancer cells.
Microenvironment-responsive DNA-conjugated albumin nanocarriers for targeted therapy.
Milk and dairy products in cancer prevention: focus on bovine lactoferrin.
Milk Components as Cancer Chemopreventive Agents.
MiR-149 sensitizes esophageal cancer cell lines to cisplatin by targeting DNA polymerase ?.
miR-214 regulates lactoferrin expression and pro-apoptotic function in mammary epithelial cells.
Mismatch repair and DNA polymerase ? proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ? variant.
Model system for DNA replication of a plasmid DNA containing the autonomously replicating sequence from Saccharomyces cerevisiae.
Modifying effects of lactoferrin in vitro on molecular phenotype of human breast cancer cells.
Modulation of endometrial steroid receptors and growth regulatory genes by tamoxifen.
Molecular Aspects of Colorectal Adenomas: The Interplay among Microenvironment, Oxidative Stress, and Predisposition.
Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro.
Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma.
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations.
Moloney murine leukemia virus-induced tumors: recombinant proviruses in active chromatin regions.
Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay.
Monitoring the therapy of human tumor xenografts in nude mice by the use of lactate dehydrogenase.
Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth.
Morphologic, Immunophenotypic and Molecular Features of Hypermutation in Colorectal Carcinomas with Mutations in DNA Polymerase ? (POLE).
Mouse DNA polymerase accompanied by a novel RNA polymerase activity: purification and partial characterization.
Mouse DNA primase plays the principal role in determination of permissiveness for polyomavirus DNA replication.
Mouse papillomavirus type 1 (MmuPV1) DNA is frequently integrated in benign tumors by microhomology-mediated end-joining.
MSH6 immunohistochemical heterogeneity in colorectal cancer: comparative sequencing from different tumor areas.
MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer.
Mucoepidermoid carcinoma of the salivary glands: immunohistochemical distribution of intermediate filament proteins, involucrin and secretory proteins.
Mucoepidermoid carcinomas: immunohistochemical studies on keratin, S-100 protein, lactoferrin, lysozyme and amylase.
Mucosal spreading adenocarcinoma at the hilar portion of the lung.
Mutagenesis in vitro by DNA polymerase from an RNA tumour virus.
Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain.
Mutation analysis of 8p genes POLB and PPP2CB in bladder cancer.
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer.
Myoepitheliomas and myoepithelial adenomas of salivary gland origin. Immunohistochemical evaluation of filament proteins, S-100 alpha and beta, glial fibrillary acidic proteins, neuron-specific enolase, and lactoferrin.
Neutralization of heparin activity by neutrophil lactoferrin.
Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis.
Neutrophil extracellular traps sequester circulating tumor cells via ?1-integrin mediated interactions.
New approach to cancer therapy: heparin binding-epidermal growth factor-like growth factor as a novel targeting molecule.
New cell-signaling pathways for controlling cytomegalovirus replication.
New therapeutic strategies in the treatment of murine diseases induced by virus and solid tumors: biology and implications for the potential treatment of human leukemia, AIDS, and solid tumors.
Non-specific binding of transferrin and lactoferrin to polystyrene culture tubes: role of the radioligand.
Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients.
Novel expression vectors enabling induction of gene expression by small-interfering RNAs and microRNAs.
Nuclease sensitivity of estradiol-charged estrogen receptor binding sites in nuclei isolated from normal and neoplastic rat mammary tissues.
Nutritional roles of lactoferrin.
On the alleged high sensitivity of mouse Ehrlich-Lettre ascites tumor cells to diphtheria toxin.
On the fidelity of DNA replication. Enzyme activities associated with DNA polymerases from RNA tumor viruses.
Optimization of the Expression of DT386-BR2 Fusion Protein in Escherichia coli using Response Surface Methodology.
Oral administration of lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy.
Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo.
Orally administered bovine lactoferrin systemically inhibits VEGF(165)-mediated angiogenesis in the rat.
Orally Administered Liposomal Lactoferrin Inhibits Inflammation-Related Bone Destruction Without Interrupting Orthodontic Tooth Movement.
Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins.
p53 Plays a Key Role in the Apoptosis of Human Ovarian Cancer Cells Induced by Adenovirus-Mediated CRM197.
Papillary cystadenocarcinoma of salivary-glands - an immunohistochemical study.
Parity-dependent association between TNF-? and LTF gene polymorphisms and clinical mastitis in dairy cattle.
PARP inhibitors: polypharmacology versus selective inhibition.
Partial purification of chromosomal DNA polymerase from rat Walker tumor.
Particle-bound DNA polymerase activity in haematological disorders and normal controls.
PEI protected aptamer molecular probes for contrast-enhanced in vivo cancer imaging.
Peptide toxins directed at the matrix dissolution systems of cancer cells.
Persistence of the ten-nucleotide repeat in chromatin unfolded in urea, as revealed by digestion with deoxyribonuclease i.
PG13 packaging cells produce recombinant retroviruses carrying a diphtheria toxin mutant which kills cancer cells.
pH/temperature sensitive magnetic nanogels conjugated with Cy5.5-labled lactoferrin for MR and fluorescence imaging of glioma in rats.
Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice.
Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers.
Phase II study of denileukin diftitox for relapsed/refractory B-Cell non-Hodgkin's lymphoma.
Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase.
Plasma lactoferrin reflects neutrophil activation in psoriasis.
Pol? inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status.
POLE proofreading defects: Contributions to mutagenesis and cancer.
Poly(rA): oligo(dT)-directed DNA polymerase activity in carcinogen induced rat mammary tumors and in normal tissues.
Polyacrylamide gel electrophoresis of DNA polymerase from Ehrlich ascites tumor cells and recovery of active enzyme.
Polycitone A, a novel and potent general inhibitor of retroviral reverse transcriptases and cellular DNA polymerases.
Polymerase proofreading domain mutations: New opportunities for immunotherapy in hypermutated colorectal cancer beyond MMR deficiency.
Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.
Polymorphism and altered methylation of the lactoferrin gene in normal leukocytes, leukemic cells, and breast cancer.
Potential Clinical Applications of Multi-Functional Milk Proteins and Peptides in Cancer Management.
Potential Protective Protein Components of Cow's Milk against Certain Tumor Entities.
Preclinical studies in rats and squirrel monkeys for safety evaluation of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1).
Predicting the Role of DNA Polymerase ? Alone or with KRAS Mutations in Advanced NSCLC Patients Receiving Platinum-Based Chemotherapy.
Preferential in vitro binding of high mobility group proteins 14 and 17 to nucleosomes containing active and DNase I sensitive single-copy genes.
Presence of chelonid fibropapilloma-associated herpesvirus in tumored and non-tumored green turtles, as detected by polymerase chain reaction, in endemic and non-endemic aggregations, Puerto Rico.
Prevention of carcinogenesis and cancer metastasis by bovine lactoferrin.
Primer requirement and template specificity of the DNA polymerase of RNA tumor viruses.
Problem-solving test: analysis of DNA damage recognizing proteins in yeast and human cells.
Product definition of pleomorphic adenoma of minor salivary glands.
Production and evaluation of cytotoxic effects of DT386-BR2 fusion protein as a novel anti-cancer agent.
Production of Recombinant Human DNA Polymerase Delta in a Bombyx mori Bioreactor.
Production of recombinant human lactoferrin in the allantoic fluid of embryonated chicken eggs and its characteristics.
Production of Viral Vectors with Suicide Genes by Utilizing the Intron-Splicing Mechanism of Insect Cells.
Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma.
Proliferation inhibition of human cancer cells in combined use of electroporation with attenuated diphtheria toxin.
Prolyl isomerase Pin1 in cancer.
Protease Responsive Nanogels for Transcytosis across the Blood-Brain Barrier and Intracellular Delivery of Radiopharmaceuticals to Brain Tumor Cells.
Protection against infections by oral lactoferrin: evaluation in animal models.
Protective antitumor immunity induced by tumor cell lysates conjugated with diphtheria toxin and adjuvant epitope in mouse breast tumor models.
Protein factors in thyrotropic tumor nuclear extracts bind to a region of the mouse thyrotropin beta-subunit promoter essential for expression in thyrotropes.
Psoriasis: mechanisms and entry points for possible therapeutic interventions.
Purification and characterization of the DNA polymerase of human breast cancer particles.
Purification and properties of murine mammary tumor virus DNA polymerase.
Purified colicin as cytotoxic agent of neoplasia: comparative study with crude colicin.
Purified recombinant EBV desoxyribonuclease in serological diagnosis of nasopharyngeal carcinoma.
Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth.
Quantitative estimation of tumor metastasis by measurement of DNA polymerase activity.
Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis.
Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer.
Rate volatility and asymmetric segregation diversify mutation burden in cells with mutator alleles.
Rearranged and germline immunoglobulin kappa genes: different states of DNase I sensitivity of constant kappa genes in immunocompetent and nonimmune cells.
Recombinant baculovirus containing the diphtheria toxin A gene for malignant glioma therapy.
Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities.
Recombinant toxins for the treatment of cancer.
Reconstitution of complete SV40 DNA replication with purified replication factors.
Recurrent Clostridium difficile Infection in Children: Patient Risk Factors and Markers of Intestinal Inflammation.
Recurrent patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines.
Reduced activity of DNA polymerase prepared from bleomycin-treated cancer cells.
Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair.
Regression of chemotherapy-resistant Polymerase epsilon (POLE) ultra-mutated and MSH6 hyper-mutated endometrial tumors with nivolumab.
Regression of extranodal natural killer/T-cell lymphoma, nasal type with denileukin diftitox (Ontak) and bexarotene (Targretin): report of a case.
Regulated expression of a diphtheria toxin A-chain gene transfected into human cells: possible strategy for inducing cancer cell suicide.
Regulation of human bone marrow lactoferrin and myeloperoxidase gene expression by tumor necrosis factor-alpha.
Regulation of PKB/Akt-pathway in the chemopreventive effect of lactoferrin against diethylnitrosamine-induced hepatocarcinogenesis in rats.
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Regulatory T cells specifically suppress conventional CD8?? T cells in intestinal tumors of APCMin/+ mice.
Relative value of oestrogen receptor assay, lactoferrin content, and glucose-6-phosphate dehydrogenase activity as prognostic indicators in primary breast cancer.
Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice.
Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase ?.
Replication of damaged genomes.
Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy.
Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1.
Requirement for IFN-gamma, CD8+ T lymphocytes, and NKT cells in talactoferrin-induced inhibition of neu+ tumors.
Residual retroperitoneal tumour tissue in patients treated for metastatic non-seminomatous testicular germ cell tumours: an immunohistochemical investigation.
REV1-POL? Inhibition Enhances Cisplatin-Induced Cytotoxicity.
Revealing an Internal Stabilization Deficiency in the DNA Polymerase ? K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Reverse transcriptase associated with A-type particles from murine myeloma cells.
Reversibility of acid and alkaline deoxyribonuclease deficiency in malignant tumor cells.
RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy.
Rhipsalis (Cactaceae)-like Hierarchical Structure Based Microfluidic Chip for Highly Efficient Isolation of Rare Cancer Cells.
Ribonuclease and deoxyribonuclease activites in experimental and human tumors by the histochemical substrate film method.
Ricin-mediated cell-lysis and apoptosis of drug sensitive and resistant tumor-cells.
RNA-DNA covalent bonds between the RNA primers and the DNA products formed by RNA tumor virus DNA polymerase.
Role of actin in the responses of adrenal cells to ACTH and cyclic AMP: inhibition by DNase I.
Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation.
Role of biomarkers in the diagnosis of inflammatory bowel disease.
Role of deoxyribonuclease in cancer chemotherapy.
Safe and Efficacious Diphtheria Toxin-Based Treatment for Melanoma: Combination of a Light-On Gene-Expression System and Nanotechnology.
Screening of mammalian DNA polymerase and topoisomerase inhibitors from Garcinia mangostana L. and analysis of human cancer cell proliferation and apoptosis.
Searching for highly sensitive and specific biomarkers for sepsis: State-of-the-art in post-mortem diagnosis of sepsis through immunohistochemical analysis.
Sebaceous carcinoma of the parotid gland. An immunohistochemical and ultrastructural study.
Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.
Selective Inhibition of DNA Polymerase ? by a Covalent Inhibitor.
Selective Metal Ion Utilization Contributes to the Transformation of the Activity of Yeast Polymerase ? from DNA Polymerization toward RNA Polymerization.
Selective Modification of Adenovirus Replication Can Be Achieved through Rational Mutagenesis of the Adenovirus Type 5 DNA Polymerase.
Self-assembled ?-lactoglobulin-oleic acid and ?-lactoglobulin-linoleic acid complexes with antitumor activities.
Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer.
Sensitivity of cancer cells to truncated diphtheria toxin.
Separation of ribonuclease H and RNA directed DNA polymerase (reverse transcriptase) of murine type-C RNA tumor viruses.
Serine protease-induced enhancement of blood-borne metastasis of rat ascites tumour cells and its prevention with deoxyribonuclease.
Serum alkaline deoxyribonuclease activity, a sensitive marker for the therapeutic monitoring of cancer patients: methodological aspects.
Sesquiterpene antitumor agents: inhibitors of cellular metabolism.
Short communication: Pheromonicin-SA affects mRNA expression of toll-like receptors, cytokines, and lactoferrin by Staphylococcus aureus-infected bovine mammary epithelial cells.
Silencing DNA Polymerase ? Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer.
Simultaneous disruption of two DNA polymerases, Pol? and Pol?, in Avian DT40 cells unmasks the role of Pol? in cellular response to various DNA lesions.
Small antibody mimetics comprising two complementarity-determining regions and a framework region for tumor targeting.
Somatic mutations in cancer: Stochastic versus predictable.
Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy.
Specific binding of tryptophan transfer RNA to avian myeloblastosis virus RNA-dependent DNA polymerase (reverse transcriptase).
Spontaneous mutation of RNA tumour viruses.
Squirrel monkey retrovirus: an endogenous virus of a new world primate.
Stability and sub-cellular localization of DNA polymerase ? is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.
STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain.
Stimulation of activin receptor II signaling pathways inhibits differentiation of multiple gastric epithelial lineages.
Stromal cell-derived factor-1/CXCL12 selectively counteracts inhibitory effects of myelosuppressive chemokines on hematopoietic progenitor cell proliferation in vitro.
Structural basis for cisplatin DNA damage tolerance by human polymerase ? during cancer chemotherapy.
Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase ?.
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation.
Studies on ehrlich ascites tumour cells: DNA synthesis, and template activity of chromatin for DNA polymerase.
Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H.
Studies on reverse transcriptase of RNA tumor viruses. I. Localization of thermolabile DNA polymerase and RNase H activities on one polypeptide.
Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy.
Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice.
Subclinical intestinal inflammation in patients with Crohn's disease following bowel resection: a smoldering fire.
Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant.
Suppressor cytokines and regulation of myelopoiesis. Biology and possible clinical uses.
Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells.
Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha.
Survey of the association of deoxyribonuclease I polymorphism with disease.
Suspected Hereditary Cancer Syndromes in Young Patients: Heterogeneous Clinical and Genetic Presentation of Colorectal Cancers.
Synthesis of fibroma viral deoxyribonucleic acid complexes in rabbit kidney cells.
Synthesis of lactoferrin and casein by explants of bovine mammary tissue.
Synthesizing a Genetic Sensor Based on CRISPR-Cas9 for Specifically Killing p53-Deficient Cancer Cells.
Tagraxofusp, the first CD123-targeted therapy and first targeted treatment for blastic plasmacytoid dendritic cell neoplasm.
Tagraxofusp: First Global Approval.
Targeted diphtheria toxin to treat BPDCN.
Targeted Mesoporous Iron Oxide Nanoparticles-Encapsulated Perfluorohexane and a Hydrophobic Drug for Deep Tumor Penetration and Therapy.
Targeted toxin therapy for the treatment of cancer.
Targeting and eradicating cancer cells by a prostate-specific vector carrying the diphtheria toxin A gene.
Targeting backup DNA repair in cancer.
Targeting cancer with lactoferrin nanoparticles: recent advances.
Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models.
Targeting diphtheria toxin and TNF alpha expression in ovarian tumors using the H19 regulatory sequences.
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.
Targeting solid tumors via T cell receptor complementarity-determining region 3delta in an engineered antibody.
Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT.
Taurine attenuates lipopolysaccharide-induced disfunction in mouse mammary epithelial cells.
Technology evaluation: rh lactoferrin, Agennix.
Telomerase - strategies to exploit an important chemotherapeutic target.
Telomerase activity in benign and malignant adrenal tumors.
Telomerase activity in non-small cell lung carcinomas correlates with smoking status.
Telomere higher-order structure and genomic instability.
Template requirements of a DNA polymerase from Ehrlich ascites tumor cells.
Template specificities of a RNA-directed DNA polymerase from a human homologous mixed mesodermal sarcoma.
Terminal deoxynucleotidyl transferase: The story of a misguided DNA polymerase.
The anti-inflammatory effect of exogenous lactoferrin on breeding-induced endometritis when administered post-breeding in susceptible mares.
The antiproliferative effect of bovine lactoferrin on canine mammary gland tumor cells.
The association of Enamelin, Lactoferrin, and Tumour necrosis factor alpha gene polymorphisms with high caries susceptibility in Chinese children under 4 years old.
The bacterial colicin active against tumor cells in vitro and in vivo is verotoxin 1.
The combination of lactoferrin and linolenic acid inhibits colorectal tumor growth through activating AMPK/JNK-related apoptosis pathway.
The Combination of Two Bioactive Constituents, Lactoferrin and Linolenic Acid, Inhibits Mouse Xenograft Esophageal Tumor Growth by Downregulating Lithocholyltaurine and Inhibiting the JAK2/STAT3-Related Pathway.
The complete DNA sequence of lymphocystis disease virus.
The cytotoxic effects of human neutrophil peptide-1 (HNP1) and lactoferrin on oral squamous cell carcinoma (OSCC) in vitro.
The difference in the stimulation by putrescine of DNA synthesis using DNA polymerase extracts of normal rat liver or of tumour tissue or host liver from tumour-bearing rats.
The E288K Colon Tumor Variant of DNA Polymerase ? Is a Sequence Specific Mutator.
The effect of bovine milk lactoferrin on human breast cancer cell lines.
The effects of shortening lactoferrin derived peptides against tumour cells, bacteria and normal human cells.
The Emerging Role of Checkpoint Inhibition in Microsatellite Stable Colorectal Cancer.
The enzymatic basis of cyclophosphamide specificity.
The exonucleolytic nature of an alkaline deoxyribonuclease of mammary tumors of C3H mice.
The human gastric cancer-associated DNA polymerase ? variant D160N is a mutator that induces cellular transformation.
The immune response of bovine mammary epithelial cells to live or heat-inactivated Mycoplasma bovis.
The impact of size and surface ligand of gold nanorods on liver cancer accumulation and photothermal therapy in the second near-infrared window.
The importance of tumor markers in oral pathology. II. Cell membrane and cytoplasmic antigens as tumour markers.
The incidence of pulmonary tumors in mice exposed to aerosols of therapeutic agents; an evaluation of the possible carcinogenic properties of penicillin, pyribenzamine, adrenalin, cortisone, trypsin and desoxyribonuclease.
The increasing complexity of the oncofetal h19 gene locus: functional dissection and therapeutic intervention.
The inflammatory response following treatment of abdominal aortic aneurysms: a comparison between open surgery and endovascular repair.
The influence of lactoferrin on elemental homeostasis and activity of metal-containing enzymes in rats with Walker-256 carcinosarcoma.
The majority of primate-specific regulatory sequences are derived from transposable elements.
The molecular biology of selected phagocyte defects.
The pleomorphic adenoma of salivary glands transplanted on athmymic mice. A lightmicroscopical and immunohistochemical investigation.
The Polymerase Activity of Mammalian DNA Pol ? Is Specifically Required for Cell and Embryonic Viability.
The production of myeloid blood cells and their regulation during health and disease.
The production of tumour necrosis factor, tissue thromboplastin, lactoferrin and cathepsin C during lipopolysaccharide stimulation in whole blood.
The relationship between the molecular structure of natural acetogenins and their inhibitory activities which affect DNA polymerase, DNA topoisomerase and human cancer cell growth.
The replication protein A binding site in simian virus 40 (SV40) T antigen and its role in the initial steps of SV40 DNA replication.
The RNA tumour virus DNA polymerase: study of the endogenous and exogenous reactions. In: strategy of the viral genome.
The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells.
The role of the cytoskeleton in the regulation of steroidogenesis.
The specificity of a neutral deoxyribonuclease from Cancer pagurus.
The therapeutic potential of attenuated diphtheria toxin delivered by an adenovirus vector with survivin promoter on human lung cancer cells.
Therapeutic implications of cell kinetic changes after cyclophosphamide treatment in "spontaneous" and "transplantable" mammary tumors.
Thyrotropin-releasing hormone regulation of human TSHB expression: role of a pituitary-specific transcription factor (Pit-1/GHF-1) and potential interaction with a thyroid hormone-inhibitory element.
Tissue-specific expression of murine keratin K13 in internal stratified squamous epithelia and its aberrant expression during two-stage mouse skin carcinogenesis is associated with the methylation state of a distinct CpG site in the remote 5'-flanking region of the gene.
TNF? Amplifies DNaseI Expression in Renal Tubular Cells while IL-1? Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form.
TP53 mutations and survival in squamous-cell carcinoma of the head and neck.
Transcriptome profiling of Streptococcus uberis-induced mastitis reveals fundamental differences between immune gene expression in the mammary gland and in a primary cell culture model.
Treatment of blastic plasmacytoid dendritic cell neoplasm.
Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report.
Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.
TSH subunit gene promoters from a murine alpha-subunit producing tumor function normally.
Tumor antigens in neoplasms of the human parotid gland.
Tumor Lymphatic Function Regulates Tumor Inflammatory and Immunosuppressive Microenvironments.
Tumor markers in parotid gland carcinomas: immunohistochemical investigations.
Tumor Mutational Burden Guides Therapy in a Treatment Refractory
Tumor necrosis factor-alpha increases lactoferrin transcytosis through the blood-brain barrier.
Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes.
Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate.
Tumoral immune suppression by macrophages expressing fibroblast activation protein-? and heme oxygenase-1.
Tumoricidal Activity of RNase A and DNase I.
Tumour lysis as a factor affecting blood levels of CEA.
Two active forms of RD-114 virus DNA polymerase in infected cells.
Two serologic markers to monitor the engraftment, growth, and treatment response of human leukemias in severe combined immunodeficient mice.
Uncoupling of oxidative and non-oxidative mechanisms in human granulocyte-mediated cytotoxicity: use of cytoplasts and cells from chronic granulomatous disease patient.
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
Underlying mechanisms for LTF inactivation and its functional analysis in nasopharyngeal carcinoma cell lines.
Unfavorable electrostatic and steric interactions in DNA polymerase ? E295K mutant interfere with the enzyme's pathway.
Urine Lactoferrin as a Potential Biomarker Reflecting the Degree of Malignancy in Urothelial Carcinoma of the Bladder.
Use of a Novel Integrase-Deficient Lentivirus for Targeted Anti-Cancer Therapy With Survivin Promoter-Driven Diphtheria Toxin A.
Use of the Rad51 promoter for targeted anti-cancer therapy.
Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy.
Use of UITma DNA polymerase improves the PCR detection of rearranged immunoglobulin heavy chain CDR3 junctions.
Utilization of Rad51C promoter for transcriptional targeting of cancer cells.
Variations in serum alkaline DNase activity in rats during growth and treatment of tumors sensitive or resistant to therapy.
Variations in serum alkaline DNase activity. A new means for therapeutic monitoring of malignant lymphomas.
Variations in serum alkaline DNase activity: a new means to assess early detection of relapse in patients treated for acute nonlymphoblastic leukemia.
Variations in serum alkaline DNase activity: a possible clinical test for therapeutic prognosis of human tumors.
Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer.
Verrucous carcinomas of the head and neck, including those with associated squamous cell carcinoma, lack transcriptionally active high-risk human papillomavirus.
Whey protein in cancer therapy: A narrative review.
Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations.
Xeroderma pigmentosum variant and error-prone DNA polymerases.
Y-family DNA polymerases in mammalian cells.
[9th symposium on bacterial toxins. 1. On the mechanism of action of toxins. B. Cellular level. 4. On the mechanism of toxic action of diphtheria toxin on Ehrlich ascites tumor cells.]
[A preliminary study of the anti-cancer effect of tanshinone on hepatic carcinoma and its mechanism of action in mice]
[Action of ribonuclease and desoxyribonuclease on the incorporation of L-glutamic acid U-C-14 and methionine S-35 in tumor cells of Ehrlich's ascites carcinoma]
[Action of the neutral desoxyribonuclease on proliferative activity of Ehrlich ascitic tumor and of erythropoieitic cells in the chick embryo]
[Activity of acid desoxyribonuclease in the urine of normal rats & those bearing Walker tumor 256 before & after x-irradiation.]
[Anchoring cytokines to cancer cells using diphtheria toxin: better than immunotherapy by gene transfer?]
[Antigenic structure of normal and malignant breast tissue]
[Antioxidants ceruloplasmin and lactoferrin in the prevention and treatment of postoperative complications in cancer patients]
[Antitumor effect of diphtheria toxin on Ehrlich ascites tumor in mice]
[Antitumor effect of human lactoferrin against newly established human pancreatic cancer cell line SPA]
[Biochemical and physiocochemical characteristics of a type C virus isolated from spontaneous lymphosarcoma of CC57Br strain mice]
[Biomolecules suppressing myelopoiesis]
[Comparative evaluation of Black's reaction and deoxyribonuclease activity determination in malignant tumors]
[Conformational changes in the chromatin of tumor cells and the phenomenon of nuclear achromasia]
[Deoxyribonucleases in spontaneous and experimental tumors of the nervous system]
[Determination of lactoferrin in the diagnosis of diseases of the pancreas]
[DNA biosynthesis in the liver of animals bearing extra-hepatic tumors: role of DNA polymerase]
[DNAase activity in tumorous growth and the action on it of the RNA from Ehrlich tumor ascites fluid]
[Effect of DNA-tropic antineoplastic and antiparasitic agents on DNAase I activity]
[Effect of transcranial electrostimulation on clinical and laboratory characteristics in patients with gastric ulcer]
[Effects and molecular mechanisms of the biological action of weak and extremely weak magnetic fields].
[Evaluation of the antiradical protector effect of multifermented milk serum with reiterated dosage in rats]
[Genetic Mutation Screening of DNA Polymerase in Human Lung Cancer].
[Heparin-binding epidermal growth factor (HB-EGF): myth or reality?]
[HISTOCHEMICAL STUDY ON THE ACTIVITY OF ACID DESOXYRIBONUCLEASE IN CANCER OF THE UTERINE CERVIX.]
[Histone specific proteinase and DNase activity of spleen lymphocyte nuclei during oncogenesis and under the effect of hydrobromide-5-(5',6' benzocoumaroyl-3')-methylaminouracil]
[Human lactoferrin: isolation of highly purified preparations from human milk, various physico-chemical properties and distribution in normal and tumor tissues]
[Immunochemical tests in the diagnosis of diseases of the male reproductive system]
[Immunohistochemical demonstration of ceruloplasmin and lactoferrin in a series of 59 thyroid tumors]
[Immunohistochemistry of alpha-lactalbumin, lactoferrin and trans- ferrin receptor in invasive breast carcinomas with regard to tumor grading, estrogen receptor status and tumor staging]
[Inhibitory effect of human lactoferrin (neolactoferrin) on the growth of transplantable tumor in the uterine cervix of mice].
[Insertion of mouse kappa light chain immunoglobulin gene sequences into a bacterial plasmid]
[Lactoferrin and cancer of the pancreas]
[Lactoferrin and leukocytes in the blood of oncologic patients]
[Lactoferrin in human lung tumors]
[Minisatellite instability induced by okadaic acid]
[Neutral DNAse activity in rat tissues in radiation carcinogenesis]
[New function of lactoferrin: protection against cancer development and metastasis].
[ON THE LOCALIZATION OF RIBONUCLEASE (RNASE) AND DESOXYRIBONUCLEASE (DNASE) ACTIVITY IN NORMAL AND INFLAMED SKIN AND IN SKIN TUMORS.]
[Possible value of variations in the serum alkaline DNAse activity in the prognosis of cancers of the upper respiratory-digestive tract treated by chemotherapy]
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
[Purification and biochemical characteristics of actin from the rat malignancy sarcoma-45]
[Quantitative immunoenzyme determination of the lactoferrin and alpha-lactalbumin in the blood serum of cancer patients]
[Relationship between tumor cell proliferating activity and biological behavior, prognosis in laryngeal carcinoma]
[Research on the antimitotic effect of treatment with combined pancreatic desoxyribonuclease and p-(N'-methylhydrazino-methyl)-N-iso-propyl-benzamide hydrochloride on the cells of Ehrlich's ascites tumor]
[Research progress of lactoferrin as drug carriers].
[Resistance of ascitic fluid immunosuppressive factor DNA to pancreatic deoxyribonuclease]
[SERUM DESOXYRIBONUCLEASE IN THE CANCER PATIENT.]
[Serum lactoferrin level in normal conditions and in pathology]
[Significance of neutrophil extracellular trap and its markers in the early diagnosis of community-acquired pneumonia in children].
[Studies of the clone and cell expression of human lactoferritin gene]
[The activity of nuclear endonucleases and topoisomerases in the liver of rats and in diethylnitrosamine-induced tumors]
[The combined action of neutral desoxyribonuclease and ionizing radiations on the proliferative activity of the cells of Ehrlich's ascites tumor]
[THE EFFECT OF BACTERIAL DESOXYRIBONUCLEASE ON EHRLICH ASCITES TUMOR CELLS IN IN VITRO EXPERIMENTS.]
[The effect of nucleotides on oligomeric state of human lactoferrin]
[The nature of the antigenic restructuring of tumors of the human prostate]
[The superoxide theory of pathogenesis and therapy of immune disorders]
[Use of tumor markers in the diagnosis of salivary gland tumors]
[Value and prognostic significance of alpha-lactalbumin (ALA), lactoferrin (Lfr) and HMFG-2 in primary breast cancers. An immunohistochemical study]
Neoplasms, Germ Cell and Embryonal
Residual retroperitoneal tumour tissue in patients treated for metastatic non-seminomatous testicular germ cell tumours: an immunohistochemical investigation.
Neoplasms, Squamous Cell
Silencing DNA Polymerase ? Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer.
Neoplastic Cells, Circulating
Endogenous PAD4 in Breast Cancer Cells Mediates Cancer Extracellular Chromatin Network Formation and Promotes Lung Metastasis.
Nephritis
A FURTHER STUDY OF NITROGEN RETENTION IN THE BLOOD IN EXPERIMENTAL ACUTE NEPHRITIS.
A NOTE ON NITROGEN RETENTION FOLLOWING REPEATED INJECTIONS OF NEPHROTOXIC AGENTS.
A PHYSIOLOGICAL STUDY OF EXPERIMENTAL NEPHRITIS DUE TO BACTERIAL POISONS AND CYTOTOXIC SERA.
A STUDY OF THE ELIMINATION OF PHENOLSULPHONEPHTHALEIN IN VARIOUS EXPERIMENTAL LESIONS OF THE KIDNEY.
Acquired Loss of Renal Nuclease Activity Is Restricted to DNaseI and Is an Organ-Selective Feature in Murine Lupus Nephritis.
Association between severe disease course and nephritis with Q222R polymorphism in DNAse I gene among lupus patients: An Argentine multicenter study.
Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus.
Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis.
Deposition of chromatin-IgG complexes in skin of nephritic MRL-lpr/lpr mice is associated with increased local matrix metalloprotease activities.
EXPERIMENTAL ACUTE NEPHRITIS : A STUDY OF THE ACIDOSIS, NITROGEN AND CHLORIDE RETENTION, AND OF THE PROTECTIVE ACTION OF SODIUM BICARBONATE.
Highly cationic anti-DNA antibodies in patients with lupus nephritis analyzed by two-dimensional electrophoresis and immunoblotting.
Impact of the Tumor Necrosis Factor Receptor-Associated Protein 1 (Trap1) on Renal DNaseI Shutdown and on Progression of Murine and Human Lupus Nephritis.
Nephritogenic potential of anti-DNA antibodies against necrotic nucleosomes.
Q222R polymorphism in DNAse I gene is a risk factor for nephritis in South Indian SLE patients.
Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.
Renal dendritic cells stimulate IL-10 production and attenuate nephrotoxic nephritis.
Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis.
TNF? Amplifies DNaseI Expression in Renal Tubular Cells while IL-1? Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form.
Nephrolithiasis
Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals.
Nephrosis, Lipoid
HLA alleles in frequently relapsing steroid-dependent and -resistant nephrotic syndrome in Egyptian children.
Nephrotic Syndrome
HLA alleles in frequently relapsing steroid-dependent and -resistant nephrotic syndrome in Egyptian children.
Nervous System Diseases
[Use of ribonuclease and desoxyribonuclease in several chronic nervous system diseases of viral etiology]
Neuralgia
Effect of prolonged administration of bovine lactoferrin in neuropathic pain: involvement of opioid receptors, nitric oxide and TNF-alpha.
Involvement of the nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway in the antihyperalgesic effects of bovine lactoferrin in a model of neuropathic pain.
The pain-relieving effects of lactoferrin on oxaliplatin-induced neuropathic pain.
Neuritis
Experimental study of diphtheritic polyneuritis in the rabbit and guinea pig. II. The effect of diphtheria toxin on lipide biosynthesis by guinea pig nerve.
[Use of desoxyribonuclease in the complex treatment of neuritis of the optic nerve]
Neuroblastoma
Analysis of chromatin changes associated with the expression of globin and non-globin genes in cell hybrids between erythroid and other cells.
Cell-type-specific expression of mouse DNA polymerase beta-gene is regulated by silencer elements.
Differential inhibition of multiple forms of DNA polymerase alpha from IMR-32 human neuroblastoma cells.
DNA polymerase activities in differentiating mouse neuroblastoma N-18 cells.
DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells.
Effective targeted cytotoxicity of neuroblastoma cells.
Identification of an octamer-1 transcription factor binding site in the promoter of the mouse mu-opioid receptor gene.
In vivo footprinting analysis of the Glypican 3 (GPC3) promoter region in neuroblastoma cells.
Inhibition of human neuroblastoma DNA polymerase activities by plant lectins and toxins.
Lactoferrin induced neuronal differentiation: A boon for brain tumours.
Neuron-specific expression of the human dopamine beta-hydroxylase gene requires both the cAMP-response element and a silencer region.
Sites hypersensitive to, and protected from, nuclease digestion in the regulatory region of wild-type and mutant polyoma chromatin.
Three different states of the chromatin structure of the mouse peripherin gene.
Tumour necrosis factor alpha and interleukin-1 beta induce specific subunits of NFKB to bind the HIV-1 enhancer: characterisation of transcription factors controlling human immunodeficiency virus type 1 gene expression in neural cells.
Two serologic markers to monitor the engraftment, growth, and treatment response of human leukemias in severe combined immunodeficient mice.
Validity of HB-EGF as Target for Human Neuroblastoma Therapy.
Neurodegenerative Diseases
Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease.
Bayesian inference for parameter estimation in lactoferrin-mediated iron transport across blood-brain barrier.
Enhanced brain delivery of deferasirox-lactoferrin conjugates for iron chelation therapy in neurodegenerative disorders: in vitro and in vivo studies.
Lactoferrin from bovine colostrum regulates prolyl hydroxylase 2 activity and prevents prion protein-mediated neuronal cell damage via cellular prion protein.
Lactoferrin induces cell surface retention of prion protein and inhibits prion accumulation.
Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier.
Tumor necrosis factor-alpha increases lactoferrin transcytosis through the blood-brain barrier.
Neutropenia
Correlation of in vitro and in vivo effects of gold compounds on leukocyte function: possible mechanisms of action.
Correlation of lactoferrin with neutrophilic inflammation in body fluids.
Lethal adult respiratory distress syndrome after meningococcal septicemia biochemical markers in bronchoalveolar lavage.
Low polymorphonuclear cell degranulation during citrate anticoagulation: a comparison between citrate and heparin dialysis.
Neutropenia induced by systemic infusion of lactoferrin.
Plasma lactoferrin content in neutropenic patients: effects of treatment with recombinant granulocyte-macrophage colony-stimulating factor.
Plasma lactoferrin in patients with neutropenia.
Plasma lactoferrin reflects granulocyte activation in vivo.
Pulmonary leukosequestration without hypoxemia during hemodialysis.
Reduction of granulocyte activation during hemodialysis with regional citrate anticoagulation: dissociation of complement activation and neutropenia from neutrophil degranulation.
Serum levels of lactoferrin and myeloperoxidase in chronic idiopathic and secondary neutropenia. A preliminary report.
Serum myeloperoxidase and lactoferrin in neutropenia.
The effect of auranofin on polymorphonuclear granulocytes.
[Plasma lactoferrin and the blood count of polynuclear neutrophils]
Non-alcoholic Fatty Liver Disease
Lactoferrin attenuates fatty acid-induced lipotoxicity via Akt signaling in hepatocarcinoma cells.
Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice.
Non-ST Elevated Myocardial Infarction
Coronary stenting is associated with an acute increase in plasma myeloperoxidase in stable angina patients but not in patients with acute myocardial infarction.
Serum deoxyribonuclease I activity can be a useful diagnostic marker for the early diagnosis of unstable angina pectoris or non-ST-segment elevation myocardial infarction.
Obesity
Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively.
Binding of lactoferrin to the surface of low-density lipoproteins modified by myeloperoxidase prevents intracellular cholesterol accumulation by human blood monocytes.
Characterization of expression of hypothalamic appetite-regulating peptides in obese hyperleptinemic brown adipose tissue-deficient (uncoupling protein-promoter-driven diphtheria toxin A) mice.
Decreased circulating lactoferrin in insulin resistance and altered glucose tolerance as a possible marker of neutrophil dysfunction in type 2 diabetes.
Fat-Produced Adipsin Regulates Inflammatory Arthritis.
Gene expression profiling and association of circulating lactoferrin level with obesity-related phenotypes in Latino youth.
Lactoferrin increases (172Thr)AMPK phosphorylation and insulin-induced (p473Ser)AKT while impairing adipocyte differentiation.
Metabolic Health in Obese Subjects-Is There a Link to Lactoferrin and Lactoferrin Receptor-Related Gene Polymorphisms?
Regulation of lymphatic function and injury by nitrosative stress in obese mice.
Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
Role of neuropeptide Y in diet-, chemical- and genetic-induced obesity of mice.
Study of lactoferrin gene expression in human and mouse adipose tissue, human preadipocytes and mouse 3T3-L1 fibroblasts. Association with adipogenic and inflammatory markers.
Trangenic and knockout rodents: novel insights into mechanisms of body weight regulation.
Obesity, Abdominal
Potent anti-obesity effect of enteric-coated lactoferrin: decrease in visceral fat accumulation in Japanese men and women with abdominal obesity after 8-week administration of enteric-coated lactoferrin tablets - CORRIGENDUM.
Potent anti-obesity effect of enteric-coated lactoferrin: decrease in visceral fat accumulation in Japanese men and women with abdominal obesity after 8-week administration of enteric-coated lactoferrin tablets.
Obesity, Metabolically Benign
Metabolic Health in Obese Subjects-Is There a Link to Lactoferrin and Lactoferrin Receptor-Related Gene Polymorphisms?
Obesity, Morbid
Changes in C-reactive protein, neopterin and lactoferrin differ after conservative and surgical weight loss in individuals with morbid obesity.
Fat Overload Induces Changes in Circulating Lactoferrin That Are Associated With Postprandial Lipemia and Oxidative Stress in Severely Obese Subjects.
Obstetric Labor, Premature
Amniotic-fluid Lactoferrin: A Marker for Subclinical Intraamniotic Infection Prior to 32 Weeks Gestation.
Eukaryote-Made Thermostable DNA Polymerase Enables Rapid PCR-Based Detection of Mycoplasma, Ureaplasma and Other Bacteria in the Amniotic Fluid of Preterm Labor Cases.
Lactoferrin in intrauterine infection, human parturition, and rupture of fetal membranes.
Lysozyme in cervical mucus of patients with chorioamnionitis.
Recombinant human lactoferrin has a potential to suppresses uterine cervical ripening in preterm delivery in animal model.
Recombinant human lactoferrin inhibits matrix metalloproteinase (MMP-2, MMP-3, and MMP-9) activity in a rabbit preterm delivery model.
Odontogenic Cysts
Evidence for the presence of lactoferrin in odontogenic keratocyst fluids.
Lactoferrin in aspirates of odontogenic cyst fluid.
Quantitation of lactoferrin in odontogenic cyst fluids.
Oligodendroglioma
Tumour necrosis factor alpha and interleukin-1 beta induce specific subunits of NFKB to bind the HIV-1 enhancer: characterisation of transcription factors controlling human immunodeficiency virus type 1 gene expression in neural cells.
Oligospermia
Seminal plasma lactoferrin concentrations in normal and abnormal semen samples.
Onchocerciasis
Neutrophil activation in ivermectin-treated onchocerciasis patients.
Ophthalmoplegia
Distal myopathy with cachexia: an unrecognised phenotype caused by dominantly-inherited mitochondrial polymerase ? mutations.
Sequence-specific stalling of DNA polymerase ? and the effects of mutations causing progressive ophthalmoplegia.
Ophthalmoplegia, Chronic Progressive External
A rare case of mitochondriopathy with autosomal dominant progressive external ophthalmoplegia diagnosed through skeletal muscle biopsy.
Oral Manifestations
Salivary lactoferrin in HIV-infected children: correlation with Candida albicans carriage, oral manifestations, HIV infection and its antifungal activity.
Oral Ulcer
Evaluation of bovine lactoferrin as a topical therapy for chemotherapy-induced mucositis in the golden Syrian hamster.
Osteoarthritis
Cytidine deaminase and lactoferrin in inflammatory synovial fluids. Indicators of local polymorphonuclear cell function?
Expression of lactoferrin on neutrophil granulocytes from synovial fluid and peripheral blood of patients with rheumatoid arthritis.
Increased levels of lactoferrin in synovial fluid but not in serum from patients with rheumatoid arthritis.
Lactoferrin accelerates chondrocyte proliferation in osteoarthritis rats through the MAPK signaling pathway.
Lactoferrin and lysozyme levels in synovial fluid: differential indices of articular inflammation and degradation.
The effect of oral administration of iron saturated-bovine lactoferrin encapsulated chitosan-nanocarriers on osteoarthritis.
Osteochondroma
Immunolocalization of lactoferrin in cartilage-forming neoplasms.
Osteoma, Osteoid
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Osteomyelitis
Comparable efficacies of the antimicrobial peptide human lactoferrin 1-11 and gentamicin in a chronic methicillin-resistant Staphylococcus aureus osteomyelitis model.
Destructive osteomyelitis associated with early secondary syphilis in an HIV-positive patient diagnosed by Treponema pallidum DNA polymerase chain reaction.
[Experience with the use of streptokinase and streptodornase in osteomyelitis.]
[The dynamics of changes in lysozyme activity and content of lactoferrin content of patients with chronic osteomyelitis].
Osteonecrosis
Efficacy of bovine lactoferrin in the post-surgical treatment of patients suffering from bisphosphonate-related osteonecrosis of the jaws: an open-label study.
Osteoporosis
Comprehensive Analysis of the Genetic and Epigenetic Mechanisms of Osteoporosis and Bone Mineral Density.
Coupling Hydroxyapatite Nanocrystals with Lactoferrin as a Promising Strategy to Fine Regulate Bone Homeostasis.
Iron loading: a risk factor for osteoporosis.
Lactoferrin ameliorates aging-suppressed osteogenesis via IGF1 signaling.
Lactoferrin and bone; structure-activity relationships.
Lactoferrin as an effector molecule in the skeleton.
Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo.
Lactoferrin promotes bone growth.
Lactoferrin promotes MC3T3-E1 osteoblast cells proliferation via MAPK signaling pathways.
Lactoferrin--a novel bone growth factor.
[The importance of lactoferrin in bone regeneration].
Osteoporosis, Postmenopausal
Bovine lactoferrin improves bone status of ovariectomized mice via immune function modulation.
Oral bovine lactoferrin improves bone status of ovariectomized mice.
Osteosarcoma
Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro.
Changes in chromatin structure support constitutive and developmentally regulated transcription of the bone-specific osteocalcin gene in osteoblastic cells.
DNase I hypersensitive sites in promoter elements associated with basal and vitamin D dependent transcription of the bone-specific osteocalcin gene.
Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.
Increasing alkaline DNase activity with substrate specificity for denaturated DNA after high dose methotrexate therapy.
Lactoferrin immuno-expression in human normal and neoplastic bone tissue.
Missing neutral DNase activity in lymphocytes and phytohemagglutinin-stimulated lymphocytes after high dose methotrexate therapy.
Molecular mechanisms underlying the inhibitory effects of bovine lactoferrin on osteosarcoma.
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization.
Otitis
Alternative therapies in antibiotic-resistant infection.
Enzyme treatment of ear infections. Local use of pancreatic dornase.
[The use of lyase and desoxyribonuclease in acute otitis in children]
Otitis Media
Cholesterol granuloma.
Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group.
Human lactoferrin proteolytic activity: analysis of the cleaved region in the IgA protease of Haemophilus influenzae.
Immune response to surface protein A of Streptococcus pneumoniae and to high-molecular-weight outer membrane protein A of Moraxella catarrhalis in children with acute otitis media.
Lactoferrin in middle ear effusion.
Role of fimbriae expressed by nontypeable Haemophilus influenzae in pathogenesis of and protection against otitis media and relatedness of the fimbrin subunit to outer membrane protein A.
[Current interest of antipneumococcal vaccination]
Otitis Media with Effusion
Bacterial and polymorphonuclear leukocyte contribution to middle ear inflammation in chronic otitis media with effusion.
Does the bacterial DNA found in middle ear effusions come from viable bacteria?
Lactoferrin in middle ear effusion.
Otitis Media, Suppurative
[Pancreatic fibrinokinase and desoxyribonuclease and its clinical and bacteriological effects in local treatment of chronic purulent otitis media.]
Out-of-Hospital Cardiac Arrest
Imbalance between plasma double-stranded DNA and deoxyribonuclease activity predicts mortality after out-of-hospital cardiac arrest.
Ovarian Cysts
Decreased lactoferrin levels in peritoneal fluid of women with minimal endometriosis.
Ovarian Neoplasms
A Possible Clinical Adaptation of CRM197 in Combination with Conventional Chemotherapeutic Agents for Ovarian Cancer.
CRM197 reverses paclitaxel resistance by inhibiting the NAC-1/Gadd45 pathway in paclitaxel-resistant ovarian cancer cells.
Cross-reacting material 197 reverses the resistance to paclitaxel in paclitaxel-resistant human ovarian cancer.
Cross-reacting material 197, a heparin-binding EGF-like growth factor inhibitor, reverses the chemoresistance in human cisplatin-resistant ovarian cancer.
Detection of Somatic Mutation in Exon 12 of DNA Polymerase ? in Ovarian Cancer Tissue Samples
Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences.
Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells.
Enhanced expression of DNA polymerase eta contributes to cisplatin resistance of ovarian cancer stem cells.
Eradication of Human Ovarian Cancer Cells by Transgenic Expression of Recombinant DNASE1, DNASE1L3, DNASE2, and DFFB Controlled by EGFR Promoter: Novel Strategy for Targeted Therapy of Cancer.
Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition.
Impact of ERCC1, XPF and DNA Polymerase ? Expression on Platinum Response in Patient-Derived Ovarian Cancer Xenografts.
In vitro expression of the diphtheria toxin A-chain gene under the control of human chorionic gonadotropin gene promoters as a means of directing toxicity to ovarian cancer cell lines.
Investigation of human cationic antimicrobial protein-18 (hCAP-18), lactoferrin and CD163 as potential biomarkers for ovarian cancer.
p53 Plays a Key Role in the Apoptosis of Human Ovarian Cancer Cells Induced by Adenovirus-Mediated CRM197.
Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer.
Targeting diphtheria toxin and TNF alpha expression in ovarian tumors using the H19 regulatory sequences.
Targeting the heparin-binding epidermal growth factor-like growth factor in ovarian cancer therapy.
The anti-tumor effect of cross-reacting material 197, an inhibitor of heparin-binding EGF-like growth factor, in human resistant ovarian cancer.
The use of the MTT assay to study drug resistance in fresh tumour samples.
Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report.
[Reverse of the resistance to paclitaxel of the heparin binding-epidermal growth factor-like growth factor inhibitor in ovarian cancer].
Pancreatic Diseases
Biochemical and clinical studies on human pancreatic deoxyribonuclease I inhibitor.
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Clinical studies on human pancreatic deoxyribonuclease I.
Desoxyribonuclease I activity in pancreatic disease.
Diagnosis of chronic pancreatitis by measurement of lactoferrin in duodenal juice.
Lactoferrin and albumin in human pancreatic juice: a valuable test for diagnosis of pancreatic diseases.
Lactoferrin in pure pancreatic juice.
Lactoferrin in the duodenal juice of patients with chronic calcifying pancreatitis.
Lactoferrin secretion in alcoholic pancreatic disease.
Radioimmunoassay of lactoferrin in pancreatic juice as a test for pancreatic diseases.
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
[Application of lactoferrin in the diagnosis of pancreatic disease -development of the radioimmunoassay of Lactoferrin and its clinical application]
[Behavior of blood amylase and plasma deoxyribonuclease I in dogs subjected to intra-operative cholangiography with the use of B 10610]
[Determination of lactoferrin in the diagnosis of diseases of the pancreas]
[Lactoferrin: biochemistry, physiological roles, and value in human biology]
[Our experiences with lactoferrin determination in the diagnosis of pancreatopathies]
Pancreatic Neoplasms
Anthrax Protective Antigen Retargeted with Single-Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells.
Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation.
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Clinical studies on human pancreatic deoxyribonuclease I.
Deoxyribonuclease I serum activity in pancreatic cancer.
Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis.
H19-promoter-targeted therapy combined with gemcitabine in the treatment of pancreatic cancer.
Heat-induced transcription of diphtheria toxin A or its variants, CRM176 and CRM197: implications for pancreatic cancer gene therapy.
Hypoxia induces upregulation of the deoxyribonuclease I gene in the human pancreatic cancer cell line QGP-1.
Lactoferrin concentration in the parotid saliva of patients with chronic pancreatitis.
Lactoferrin in pure pancreatic juice.
Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Ribonucleases and deoxyribonucleases in pancreatic cancer: clinical value and pathophysiological interrelationships.
Serum deoxyribonuclease and ribonuclease in pancreatic cancer and chronic pancreatitis.
Specific targeting of tumor vasculature by diphtheria toxin-vascular endothelial growth factor fusion protein reduces angiogenesis and growth of pancreatic cancer.
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer.
[Antitumor effect of human lactoferrin against newly established human pancreatic cancer cell line SPA]
[Lactoferrin and cancer of the pancreas]
Pancreatic Pseudocyst
The treatment of chronic recurrent pancreatitis with depot secretin--a preliminary report.
Pancreatitis
A non competitive enzyme immunoassay of human lactoferrin in biological fluids.
Cancer, pancreatitis, and the detection of the isoenzymes of DNAase, RNAase and amylase.
Characterization of an additional protein in pancreatic juice of men with chronic calcifying pancreatitis. Identification to lactoferrin.
Dendritic Cells Promote Pancreatic Viability in Mice with Acute Pancreatitis.
Development of a radioimmunoassay for human deoxyribonuclease I.
Duodenal output and concentration of lactoferrin in chronic pancreatitis: correlation to amylase secretion and duct morphology.
Experimental immune-mediated pancreatitis in neonatally thymectomized mice immunized with carbonic anhydrase II and lactoferrin.
Immunocytochemical localization of lactoferrin in human pancreas.
Immunohistochemical detection of lactoferrin in different human glandular tissues with special reference to the exocrine pancreas.
Lactoferrin and albumin in human pancreatic juice: a valuable test for diagnosis of pancreatic diseases.
Lactoferrin concentration in the parotid saliva of patients with chronic pancreatitis.
Lactoferrin in acute necrotizing pancreatitis.
Lactoferrin in pure pancreatic juice.
Lactoferrin in the duodenal juice of patients with chronic calcifying pancreatitis.
Lactoferrin secretion in alcoholic pancreatic disease.
Lactoferrin stimulates killing and clearance of bacteria but does not prevent mortality of diabetic mice.
Pancreatic stone protein of pancreatic calculi in chronic calcified pancreatitis in man.
Plasma lactoferrin levels in patients with chronic calcifying pancreatitis.
Protective effect of lactoferrin on caerulein-induced acute pancreatitis in rats.
Relationship between pancreatic enzymes and pathological changes in the pancreas in acute pancreatitis. The significance of determination of serum deoxyribonuclease.
Selectively aspirated pure pancreatic secretion. Viscosity, trypsin activity, protein concentration and lactoferrin content of pancreatic juice in chronic pancreatitis.
The activity of desoxyribonuclease I in serum in acute pancreatitis.
The treatment of chronic recurrent pancreatitis with depot secretin--a preliminary report.
[Dynamics of expression of cytokines and lactoferrin in patients with chronic alcohol pancreatitis and chronic relapsing pancreatitis]
[Lactoferrin in chronic calcifying pancreatitis. Hypothesis for the biological role of the protein]
[Study of lactoferrin in the pancreatico-duodenal juice. Limitations in the diagnosis of chronic pancreatitis]
[Study of salivary lactoferrin in prophylactic examinations]
[The value of the plasmatic level of desoxyribonuclease I in the diagnosis of acute experimental pancreatitis]
Pancreatitis, Acute Necrotizing
Lactoferrin in acute necrotizing pancreatitis.
[Desoxyribonuclease II activity of the blood in pancreatic necrosis caused by experimental Coxsackie virus infection.]
Pancreatitis, Chronic
Biochemical and clinical studies on human pancreatic deoxyribonuclease I inhibitor.
Clinical investigation of serum deoxyribonuclease: II. Clinical studies of serum deoxyribonuclease activity in pancreatic disease.
Clinical studies on human pancreatic deoxyribonuclease I.
Deoxyribonuclease I serum activity in pancreatic cancer.
Diagnosis of chronic pancreatitis by measurement of lactoferrin in duodenal juice.
Duodenal lactoferrin in patients with chronic pancreatitis and gastrointestinal diseases.
Duodenal output and concentration of lactoferrin in chronic pancreatitis: correlation to amylase secretion and duct morphology.
Immunohistochemical detection of lactoferrin in different human glandular tissues with special reference to the exocrine pancreas.
Lactoferrin concentration in the parotid saliva of patients with chronic pancreatitis.
Lactoferrin in acute necrotizing pancreatitis.
Lactoferrin in chronic pancreatitis.
Lactoferrin in pure pancreatic juice in chronic pancreatitis.
Lactoferrin in pure pancreatic juice.
Lactoferrin secretion in alcoholic pancreatic disease.
Pancreatic exocrine and endocrine responses in chronic pancreatitis.
Pancreatic stone protein and lactoferrin in human pancreatic juice in chronic pancreatitis.
Pancreatic stone protein of pancreatic calculi in chronic calcified pancreatitis in man.
Radioimmunoassay of lactoferrin in pancreatic juice as a test for pancreatic diseases.
Salivary secretion in chronic pancreatitis with special reference to albumin and lactoferrin.
Secretory component and lactoferrin in pure pancreatic juice in chronic pancreatitis.
Selectively aspirated pure pancreatic secretion. Viscosity, trypsin activity, protein concentration and lactoferrin content of pancreatic juice in chronic pancreatitis.
Serum deoxyribonuclease and ribonuclease in pancreatic cancer and chronic pancreatitis.
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
[Biochemical analysis of chronic pancreatitis and lactoferrin]
[Clinical trial on pancreatic duct stones caused by chronic pancreatitis.]
[Critical study of the analysis of lactoferrin in duodenal fluid in the diagnosis of chronic pancreatitis]
[Determination of lactoferrin in the diagnosis of diseases of the pancreas]
[Diagnosis of chronic pancreatitis based on the determination of lactoferrin and calcium in the duodenal juice?]
[Global pancreatic and gastric deficiency after a familial membranous glomerulonephritis in a child treated by corticoids and chlorambucil for a long time (author's transl)]
[Lactoferrin levels in pure pancreatic secretion of chronic pancreatitis (author's transl)]
[Lactoferrin of duodenal juice in chronic pancreatitis (author's transl)]
[Lactoferrin]
[Study of lactoferrin in the pancreatico-duodenal juice. Limitations in the diagnosis of chronic pancreatitis]
Papilloma
Energy transfer between a nanosystem and its host fluid: a multiscale factorization approach.
Penile cutaneous horn ten years after treatment of verrucous squamous cell carcinoma on penile glans: case report.
RIBONUCLEASE AND DEOXYRIBONUCLEASE ACTIVITIES IN RAT AND MOUSE STRATIFIED SQUAMOUS EPITHELIA AND SKIN PAPILLOMAS.
Structure, DNaseI hypersensitivity and expression of integrated papilloma virus in the genome of HeLa cells.
The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase.
The importance of tumor markers in oral pathology. II. Cell membrane and cytoplasmic antigens as tumour markers.
Papillomavirus Infections
Genital Human Papillomavirus Infection in Indian HIV-Seropositive Men Who Have Sex With Men.
High-risk papillomavirus infection is associated with altered antibody responses in genital tract: non-specific responses in HPV infection.
Keratinizing odontogenic cysts with a spectrum of verrucoid morphology: investigation of a potential role of human papillomavirus.
Prevalence of Anal HPV Infection Among HIV-Positive Men Who Have Sex With Men in India.
Role of the human papillomavirus in malignant transformation of oral leukoplakia distinct from oropharyngeal squamous cell carcinoma: A study of 76 patients with internal-control specimens.
[Detection of human papillomavirus DNA in uterine cervix by polymerase chain reaction (PCR) method]
Parakeratosis
Dnases in health and disease.
Identification of functional SNPs potentially served as a genetic risk factor for the pathogenesis of parakeratosis in the gene encoding human deoxyribonuclease I-like 2 (DNase 1L2) implicated in terminal differentiation of keratinocytes.
IL-23 from Langerhans Cells Is Required for the Development of Imiquimod-Induced Psoriasis-Like Dermatitis by Induction of IL-17A-Producing ?? T Cells.
Survey of single-nucleotide polymorphisms in the gene encoding human deoxyribonuclease I-like 2 producing loss of function potentially implicated in the pathogenesis of parakeratosis.
Paralysis
Demyelination following diphtheria toxin in the presence of axonal atrophy.
[Electromyographical study of paralysis caused by diphtheria toxin in guinea pigs.]
Paraproteinemias
Epstein-Barr Virus and Monoclonal Gammopathy of Clinical Significance in Autologous Stem Cell Transplantation for Multiple Sclerosis.
PCR with degenerate primers for highly conserved DNA polymerase gene of the herpesvirus family shows neither human herpesvirus 8 nor a related variant in bone marrow stromal cells from multiple myeloma patients.
Parasitemia
Molecular analysis of non-specific protection against murine malaria induced by BCG vaccination.
Parasitic Diseases
Effect of lactoferrin protein on red blood cells and macrophages: mechanism of parasite-host interaction.
Paratuberculosis
Effects of mycobactin J and lactoferrin supplementation of drinking water on the in vivo multiplication of Mycobacterium paratuberculosis in gnotobiotic mice.
Immunohistochemical distribution of ferritin, lactoferrin, and transferrin in granulomas of bovine paratuberculosis.
Inability to detect mycobactin in mycobacteria-infected tissues suggests an alternative iron acquisition mechanism by mycobacteria in vivo.
The distribution of ferritin, lactoferrin and transferrin in granulomatous lymphadenitis of bovine paratuberculosis.
Parkinson Disease
Altered systemic iron metabolism in Parkinson's disease.
Assessment of plasma lactoferrin in Parkinson's disease.
Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson's disease.
Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease.
Iron transport in Parkinson's disease.
Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: preparation, characterization and efficacy in Parkinson's disease.
Lactoferrin for Mental Health: Neuro-Redox Regulation and Neuroprotective Effects across the Blood-Brain Barrier with Special Reference to Neuro-COVID-19.
Lactoferrin is synthesized by mouse brain tissue and its expression is enhanced after MPTP treatment.
Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP-induced Parkinson's disease in mice.
Membrane proteins in four acts: function precedes structure determination.
Pretreatment with Human Lactoferrin Had a Positive Effect on the Dynamics of Mouse Nigrostriatal System Recovery after Acute MPTP Exposure.
Targeting cancer with lactoferrin nanoparticles: recent advances.
The Iron-Binding Protein Lactoferrin Protects Vulnerable Dopamine Neurons from Degeneration by Preserving Mitochondrial Calcium Homeostasis.
Parkinsonian Disorders
Mesencephalic complex I deficiency does not correlate with parkinsonism in mitochondrial DNA maintenance disorders.
The DNA polymerase {gamma} Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine.
Parotitis
Alterations in lactoferrin in salivary gland disease.
Changes in lactoferrin and other proteins in a case of chronic recurrent parotitis.
Lactoferrin concentration in the parotid saliva of patients with chronic pancreatitis.
Salivary factors in children with recurrent parotitis. Part 2: Protein, albumin, amylase, IgA, lactoferrin lysozyme and kallikrein concentrations.
Parvoviridae Infections
Focal seizure associated with human parvovirus B19 infection in a non-encephalopathic child.
Pemphigus
[Therapeutic effectiveness of desoxyribonuclease in treatment of patients with pemphigus]
Peptic Ulcer
[Study of salivary lactoferrin in prophylactic examinations]
Peri-Implantitis
Microbiological findings and host response in patients with peri-implantitis.
Pericarditis
Use of 16S ribosomal DNA polymerase chain reaction to identify Haemophilus influenzae type b as the etiology of pericarditis in an infant.
Periodontal Diseases
Advances in periodontal diagnosis. 7. Proteolytic and hydrolytic enzymes link with periodontitis.
Application of Lactoferrin and ?1-Antitrypsin in Gingival Retention Fluid to Diagnosis of Periodontal Disease.
Decreased lactoferrin content in granulocytes from subjects with Actinobacillus actinomycetemcomitans associated periodontal diseases.
Diabetic Lactoferrin Deficient Mice Demonstrates Greater Susceptibility to Experimental Periodontal Disease.
Elevated levels of salivary lactoferrin, a marker for chronic periodontitis?
Human trial of liposomal lactoferrin supplementation for periodontal disease.
Lactoferrin and oral diseases: current status and perspective in periodontitis.
Lactoferrin in the gingival crevice as a marker of polymorphonuclear leucocytes in periodontal diseases.
Lactoferrin Knockout Mice Demonstrates Greater Susceptibility to Aggregatibacter Actinomycetemcomitans-Induced Periodontal Disease.
Lactoferrin, a Marker for Periodontal Disease.
Lactoferrin: A Roadmap to the Borderland between Caries and Periodontal Disease.
LTF and DEFB1 polymorphisms are associated with susceptibility toward chronic periodontitis development.
Salivary lactoferrin and low-Mr mucin MG2 in Actinobacillus actinomycetemcomitans-associated periodontitis.
The investigation of glutathione peroxidase, lactoferrin, myeloperoxidase and interleukin-1beta in gingival crevicular fluid: implications for oxidative stress in human periodontal diseases.
Periodontal Pocket
Degradation of lactoferrin by periodontitis-associated bacteria.
Effect of lactoferrin on interaction of Prevotella intermedia with plasma and subepithelial matrix proteins.
Human lactoferrin binding to Porphyromonas gingivalis, Prevotella intermedia and Prevotella melaninogenica.
Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva.
Periodontitis
Aberrant neutrophil reactions in periodontitis.
Altered levels of salivary biochemical markers in periodontitis.
Association between lactoferrin gene polymorphisms and aggressive periodontitis among Taiwanese patients.
Bovine lactoferrin inhibits alveolar bone destruction in an orthodontic rat model with periodontitis.
Cleaved inflammatory lactoferrin peptides in parotid saliva of periodontitis patients.
Differential expression of salivary glycoproteins in aggressive and chronic periodontitis.
Elastase and lactoferrin in gingival crevicular fluid: possible indicators of a granulocyte-associated specific host response.
Gingival crevicular fluid lactoferrin levels in adult periodontitis patients.
Increased release of free oxygen radicals from peripheral neutrophils in adult periodontitis after Fc delta-receptor stimulation.
Inhibitory effects of orally administrated liposomal bovine lactoferrin on the LPS-induced osteoclastogenesis.
Lactoferrin and oral diseases: current status and perspective in periodontitis.
Lactoferrin gene polymorphisms in Italian patients with recurrent tonsillitis.
Lactoferrin: A Roadmap to the Borderland between Caries and Periodontal Disease.
Oral Diagnostic Methods for the Detection of Periodontal Disease.
Orally Administered Liposomal Lactoferrin Inhibits Inflammation-Related Bone Destruction Without Interrupting Orthodontic Tooth Movement.
Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva.
Periodontitis, periodontopathic bacteria and lactoferrin.
Salivary lactoferrin and low-Mr mucin MG2 in Actinobacillus actinomycetemcomitans-associated periodontitis.
The investigation of glutathione peroxidase, lactoferrin, myeloperoxidase and interleukin-1beta in gingival crevicular fluid: implications for oxidative stress in human periodontal diseases.
The relationship between elastase and lactoferrin in healthy, gingivitis and periodontitis sites.
Peritonitis
Acute peritonitis due to Corynebacterium ulcerans in a patient receiving continuous ambulatory peritoneal dialysis: a case report and literature review.
Ascitic fluid lactoferrin for diagnosis of spontaneous bacterial peritonitis.
Lactoferrin in gastrointestinal disease.
Usefulness of ascitic fluid lactoferrin levels in patients with liver cirrhosis.
[A clinical application of the fibrinolytic streptococcic activator; post-operative ileus caused by massive tubercular fibroadhesive peritonitis; re-operation; intraperitoneal administration of streptodornase and streptokinase; recovery.]
[Dynamics of content of an acute phase of inflammation proteins in extended peritonitis].
Persistent Infection
A virus in Beechey ground squirrels that is related to hepatitis B virus of humans.
Characterization of immune response in Staphylococcus aureus chronically infected bovine mammary glands during active involution.
Foxp3+ regulatory T cells control persistence of viral CNS infection.
Genetic variation among hepatitis B and related viruses.
OmpA of uropathogenic Escherichia coli promotes post-invasion pathogenesis of cystitis.
Persistent infection of primary human cell cultures with rubella variant carrying DNA Polymerase activity.
Pharyngitis
Anti-invasive activity of bovine lactoferrin towards group A streptococci.
Comparison of the antibody response to streptococcal cellular and extracellular antigens in acute pharyngitis.
Comprehensive analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever.
Pheochromocytoma
Differentiation of rat pheochromocytoma cells by fomitellic acids, specific DNA polymerase inhibitors.
Transposition of DNase hypersensitive chromatin to the nuclear periphery coincides temporally with nerve growth factor-induced up-regulation of gene expression in PC12 cells.
Pick Disease of the Brain
Lactoferrin induces cell surface retention of prion protein and inhibits prion accumulation.
Picornaviridae Infections
Highlights in the development of new antiviral agents.
Pilonidal Sinus
Streptokinase and streptodornase in the treatment of pilonidal cysts.
Pituitary Neoplasms
Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: potential for cytotoxic gene therapy.
Chromatin structure, transcription, and methylation of the prolactin gene domain in pituitary tumors of Fischer 344 rats.
Nuclear factor-I and activator protein-2 bind in a mutually exclusive way to overlapping promoter sequences and trans-activate the human growth hormone gene.
The transcriptional regulation of the growth hormone gene is conserved in vertebrate evolution.
Plague
The yersiniabactin transport system is critical for the pathogenesis of bubonic and pneumonic plague.
Plasmacytoma
An active chromatin structure acquired by translocated c-myc genes.
Effects of sodium butyrate on the rearranged c-myc expression in mouse plasmacytoma cells.
Reduced DNase I sensitivity of the rearranged c-myc gene in somatic cell hybrids between murine plasmacytoma cells and fibroblasts.
Pleural Effusion
A 22-year-old man with pleural tuberculosis associated hydropneumothorax: Case report and literature review.
Diagnostic value of lactoferrin analysis in pleural effusions.
Dose De-Escalation of Intrapleural Tissue Plasminogen Activator Therapy for Pleural Infection: The ADAPT Project.
Extended Dwell Time Improves Results of Fibrinolytic Therapy for Complex Pleural Effusions.
Mixing It Up: Coadministration of tPA/DNase in Complicated Parapneumonic Pleural Effusions and Empyema.
Rethinking the Doses of Tissue Plasminogen Activator and Deoxyribonuclease Administrated Concurrently for Intrapleural Therapy for Complicated Pleural Effusion and Empyema.
Pleural Effusion, Malignant
Successful drainage of complex haemoserous malignant pleural effusion with a single modified low-dose intrapleural alteplase and dornase alfa.
Pleurisy
Lactoferrin restrains allergen-induced pleurisy in mice.
[Acute purulent pleurisy treated with streptokinase and streptodornase.]
[Streptokinase and streptodornase in pleurisy and meningitis therapy.]
Pneumococcal Infections
Efficacy, immunogenicity and safety of heptavalent pneumococcal conjugate vaccine in low birth weight and preterm infants.
Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
Vaccines, emerging viruses, and how to avoid disaster.
Pneumonia
Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.
Cigarette smoke-exposed neutrophils die unconventionally but are rapidly phagocytosed by macrophages.
Clinical Effects of Bovine Lactoferrin on Two Canine Cases with Familial Neutrophil Dysfunction.
Corynebacterium ulcerans Isolated from an Asymptomatic Dog Kept in an Animal Shelter in the Metropolitan Area of Rio de Janeiro, Brazil.
Deoxyribonuclease Reduces Tissue Injury and Improves Survival After Hemorrhagic Shock.
Diagnostic value of blood cytokine concentrations in acute pneumonia.
Dornase alfa (Pulmozyme).
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.
Enzyme linked immunosorbent assay for lactoferrin. Plasma and tissue measurements.
Granulocyte recovery in pediatric marrow transplant recipients treated with ganciclovir for cytomegalovirus infection.
Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
Impaired neutrophil exocytosis in patients with severe pneumonia.
Induction of the pneumococcal vncRS operon by lactoferrin is essential for pneumonia.
Influence of oral lactoferrin on Mycobacterium tuberculosis induced immunopathology.
Inhibitory effects of lactoferrin on pulmonary inflammatory processes induced by lipopolysaccharide by modulating the TLR4-related pathway.
Intrapulmonary protein leakage in immunocompromised children and adults with pneumonia.
miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.
Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.
Outer membrane protein A inhibits the degradation of caspase-1 to regulate NLRP3 inflammasome activation and exacerbate the Acinetobacter baumannii pulmonary inflammation.
Prevention of nosocomial infections in neonatal intensive care units.
Severe Pneumonia Caused by Toxigenic Corynebacterium ulcerans Infection, Japan.
Severe Pulmonary Hemorrhage in a Neonate With Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation.
STING-dependent sensing of self-DNA drives silica-induced lung inflammation.
The intrabronchial use of streptokinase and streptodornase in the treatment of slowly resolving pneumonia.
The non-immune inflammatory response: serial changes in plasma iron, iron-binding capacity, lactoferrin, ferritin and C-reactive protein.
The significance of cytomegalovirus in children with pneumonia admitted for mechanical ventilation.
TLR3 Regulated Poly I:C-Induced Neutrophil Extracellular Traps and Acute Lung Injury Partly Through p38 MAP Kinase.
Treatment of unresolved pneumonia with streptokinase and streptodornase.
[Iron metabolism and indicators reflecting its changes in pulmonary tuberculosis (literature review).]
[Myeloperoxidase, lactoferrin and elastase in bronchoalveolar lavage and plasma in pneumonia]
[Serum lactoferrin level in normal conditions and in pathology]
[The influence of low-intensity laser irradiation of blood on the lactoferrin level in the patients presenting with community-acquired pneumonia].
[The pathogenicity enzymes of clinical strains of Klebsiella pneumoniae]
Pneumonia, Bacterial
Impairment of innate immune responses of airway epithelium by infection with bovine viral diarrhea virus.
YKL-40, a matrix protein of specific granules in neutrophils, is elevated in serum of patients with community-acquired pneumonia requiring hospitalization.
[Significance of neutrophil extracellular trap and its markers in the early diagnosis of community-acquired pneumonia in children].
Pneumonia, Mycoplasma
[Significance of neutrophil extracellular trap and its markers in the early diagnosis of community-acquired pneumonia in children].
Pneumonia, Pneumococcal
Diagnostic value of blood cytokine concentrations in acute pneumonia.
Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway.
Post-marketing effectiveness of Prevnar [pneumococcal 7-valent conjugate vaccine (diphtheria CRM197 protein)] and implications for adult immunization.
Pneumonia, Ventilator-Associated
Bronchoscopy in paediatric intensive care.
Mitochondrial DNA damage associated molecular patterns in ventilator-associated pneumonia: Prevention and reversal by intratracheal DNase I.
Molecular Characterization of Acinetobacter baumannii Isolated from Ventilator-Associated Pneumonia and Burn Wound Colonization by Random Amplified Polymorphic DNA Polymerase Chain Reaction and the Relationship between Antibiotic Susceptibility and Biofilm Production.
Pneumonia, Viral
[Significance of neutrophil extracellular trap and its markers in the early diagnosis of community-acquired pneumonia in children].
Pneumothorax
Deoxyribonuclease for cystic fibrosis.
Factors associated with poor pulmonary function: cross-sectional analysis of data from the ERCF. European Epidemiologic Registry of Cystic Fibrosis.
Pulmonary complications of cystic fibrosis.
[3 Cases of hemothorax after extrapleural pneumothorax, treated by injections of streptokinase and streptodornase.]
[First results of the use of streptodornase and streptokinase in hemothorax secondary to creation of extra-pleural pneumothorax.]
[Streptokinase and streptodornase: its use in hemothorax following extrapleural pneumothorax.]
Poliomyelitis
Combination vaccines containing DTPa-Hib: impact of IPV and coadministration of CRM197 conjugates.
In vitro virucidal effectiveness of a 0.12%-chlorhexidine gluconate mouthrinse.
Nucleases in the cerebrospinal fluid. III. Simultaneous determination of ribo- and desoxyribonuclease in the CSF of patients with poliomyelitis.
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants.
[Iron storage in tissue culture and its effect on the action of diphtheria toxin and poliomyelitis virus]
[Validation of the virus inactivation capacity of a procedure of human plasma albumin purification by chromatography]
Polyarteritis Nodosa
[Antineutrophil cytoplasmic antibodies--ANCA]
Polycythemia
Serum lactoferrin in polycythemia.
Polyomavirus Infections
Lactoferrin inhibits early steps of human BK polyomavirus infection.
Pouchitis
Biliary lactoferrin concentrations are increased in active inflammatory bowel disease: a factor in the pathogenesis of primary sclerosing cholangitis?
Consecutive Monitoring of Fecal Calprotectin and Lactoferrin for the Early Diagnosis and Prediction of Pouchitis after Restorative Proctocolectomy for Ulcerative Colitis.
Effect of probiotics (Lactobacillus plantarum 299 plus Bifidobacterium Cure21) in patients with poor ileal pouch function: a randomised controlled trial.
Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis.
Fecal lactoferrin: a noninvasive fecal biomarker for the diagnosis and surveillance of pouchitis.
Pilot study on the effect of reducing dietary FODMAP intake on bowel function in patients without a colon.
Pouch-ouch.
Serial Fecal Calprotectin and Lactoferrin Measurements for Early Diagnosis of Pouchitis After Proctocolectomy for Ulcerative Colitis: Is Pouchoscopy No Longer Needed?
The assessment of a rapid noninvasive immunochromatographic assay test for fecal lactoferrin in patients with suspected inflammation of the ileal pouch.
Poxviridae Infections
Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives.
Pre-Eclampsia
Increased systemic activation of neutrophils but not complement in preeclampsia.
Neutrophil activation and C-reactive protein concentration in preeclampsia.
Neutrophil activation in preeclampsia. Are defensins and lactoferrin elevated in preeclamptic patients?
[The regulatory transport proteins in diagnostic and prognosis of preeclampsia].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A modified nuclear DNA polymerase in a case of acute lymphoblastic leukemia.
An artificial nucleoside that simultaneously detects and combats drug resistance to doxorubicin.
Antitumor Effects of CRM197, A Specific Inhibitor of HB-EGF, in T-Cell Acute Lymphoblastic Leukemia.
Cell proliferation and DNA dependent DNA polymerase estimation in acute lymphoblastic leukaemia during treatment with prednisone and vincristine.
Diphtheria Toxin/Human B-Cell Activating Factor Fusion Protein Kills Human Acute Lymphoblastic Leukemia BALL-1 Cells: An Experimental Study.
Immunotoxins in cancer therapy: Review and update.
Inhibition of deoxyribonucleic acid polymerases from human cells and from simian sarcoma virus by pyran.
TdT expression in Merkel cell carcinoma: potential diagnostic pitfall with blastic hematological malignancies and expanded immunohistochemical analysis.
Terminal deoxynucleotidyl transferase and human leukemia.
Use of recombinant human deoxyribonuclease (DNase) for processing of a thawed umbilical cord blood transplant in a patient with relapsed acute lymphoblastic leukemia.
[Expression of lactoferrin and myeloperoxidase genes in blasts of acute lymphoblastic leukemia]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Antitumor Effects of CRM197, A Specific Inhibitor of HB-EGF, in T-Cell Acute Lymphoblastic Leukemia.
Prediabetic State
Early microvascular complications of prediabetes in mice with impaired glucose tolerance and dyslipidemia.
Pregnancy Complications
Nutritional roles of lactoferrin.
Premature Birth
The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
Vaginal lactoferrin in prevention of preterm birth in women with bacterial vaginosis.
Pressure Ulcer
Prospective randomized double-blind study of the wound-debriding effects of collagenase and fibrinolysin/deoxyribonuclease in pressure ulcers.
Primary Ovarian Insufficiency
Ameliorative effect of recombinant human lactoferrin on the premature ovarian failure in rats after cyclophosphamide treatments.
Prion Diseases
Lactoferrin from bovine colostrum regulates prolyl hydroxylase 2 activity and prevents prion protein-mediated neuronal cell damage via cellular prion protein.
Proctitis
A prospective study of faecal calprotectin and lactoferrin in the monitoring of acute radiation proctitis in prostate cancer treatment.
Extent of disease affects the usefulness of fecal biomarkers in ulcerative colitis.
Faecal calprotectin and lactoferrin as markers of acute radiation proctitis: a pilot study of eight stool markers.
Faecal calprotectin and lactoferrin values during irradiation of prostate cancer correlate with chronic radiation proctitis: Results of a prospective study.
The Efficacy of Probiotic (Lactobacillus rhamnosus GG) and 5-ASA (Aminosalicylic Acid) in the Treatment of Experimental Radiation Proctitis in Rats.
Prostatic Hyperplasia
Lactoferrin in human prostate tissue.
[Identification of low-molecular weight prostate-specific antigen(PSA) and lactoferrin in the prostatic secretion of benign prostatic hyperplasia]
[Immunochemical tests in the diagnosis of diseases of the male reproductive system]
Prostatic Neoplasms
A polymer library approach to suicide gene therapy for cancer.
A prospective study of faecal calprotectin and lactoferrin in the monitoring of acute radiation proctitis in prostate cancer treatment.
Absolute quantification of human tear lactoferrin using multiple reaction monitoring technique with stable-isotopic labeling.
Author Correction: Doxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice.
Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro.
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.
Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer.
Doxorubicin Conjugated to Immunomodulatory Anticancer Lactoferrin Displays Improved Cytotoxicity Overcoming Prostate Cancer Chemo resistance and Inhibits Tumour Development in TRAMP Mice.
Effects of exogenous lactoferrin on phenotypic profile and invasiveness of human prostate cancer cells (DU145 and LNCaP) in vitro.
Faecal calprotectin and lactoferrin values during irradiation of prostate cancer correlate with chronic radiation proctitis: Results of a prospective study.
Fatigue in patients undergoing radiation therapy: an observational study.
Homogeneous Immunochemical Assay on the Lateral Flow Strip for Measurement of DNase I Activity.
Identification and characterization of a prostate-specific androgen-independent protein-binding site in the probasin promoter.
Identification of diphtheria toxin via screening as a potent cell cycle and p53-independent cytotoxin for human prostate cancer therapeutics.
Lactoferrin-Bearing Gold Nanocages for Gene Delivery in Prostate Cancer Cells in vitro.
Regression of prostate cancer xenografts by a lentiviral vector specifically expressing diphtheria toxin A.
Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-?, TRAIL, and interleukin-12.
Regulated expression of diphtheria toxin in prostate cancer cells.
Systematic biochemical analysis of somatic missense mutations in DNA polymerase ? found in prostate cancer reveal alteration of enzymatic function.
Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology.
Understanding the loss-of-function in a triple missense mutant of DNA polymerase ? found in prostate cancer.
[Identification of low-molecular weight prostate-specific antigen(PSA) and lactoferrin in the prostatic secretion of benign prostatic hyperplasia]
[Serum lactoferrin level in normal conditions and in pathology]
Prostatitis
[Ejaculate microflora sensitivity to lactoferrin in chronic prostatitis]
[Immunochemical tests in the diagnosis of diseases of the male reproductive system]
[Lactoferrin assay in urethritis and urethral prostatitis]
[The immunochemical determination of the concentration of organ-specific ejaculate proteins in the differential diagnosis of chronic inflammatory diseases of the male reproductive system]
protein-arginine deiminase deficiency
Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury.
Proteinuria
DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features.
Urine podocyte mRNAs mark progression of renal disease.
Pruritus
Double-blinded, placebo-controlled study to evaluate an antipruritic shampoo for dogs with allergic pruritus.
Randomised clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment.
Pseudomonas Infections
Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and functionalisation with dornase alfa (DNase).
Association between practice patterns and body mass index percentile in infants and young children with cystic fibrosis.
Improvements in lung function outcomes in children with cystic fibrosis are associated with better nutrition, fewer chronic pseudomonas aeruginosa infections, and dornase alfa use.
Optimizing treatment policies and improving care: impact on outcome in patients with cystic fibrosis.
Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation.
Pseudorabies
Aphidicolin inhibits in vitro the activity of pseudorabies virus (PRV) DNA polymerase and in vivo the viral proliferation.
Characterization of monoclonal antibodies that recognize the amino- and carboxy-terminal epitopes of the pseudorabies virus UL42 protein.
Cloning, sequencing, and functional characterization of the two subunits of the pseudorabies virus DNA polymerase holoenzyme: evidence for specificity of interaction.
DNA polymerase in pseudorabies virus infected cells.
Identification of a pseudorabies virus UL12 (deoxyribonuclease) gene.
Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo.
Lactobacillus pentosus expressing porcine lactoferrin elevates antibacterial activity and improves the efficacy of vaccination against Aujeszky's disease.
Pseudorabies Virus DNA Polymerase Processivity Factor UL42 Inhibits Type I IFN Response by Preventing ISGF3-ISRE Interaction.
Targeting the pseudorabies virus DNA polymerase processivity factor UL42 by RNA interference efficiently inhibits viral replication.
The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme.
The pseudorabies virus DNA polymerase processivity factor UL42 exists as a monomer in vitro and in vivo.
Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters.
Psittacosis
Genotyping of Chlamydophila psittaci in human samples.
Psoriasis
A Systematic Review of Lactoferrin Use in Dermatology.
Erythrocyte damage in mild and severe psoriasis.
Identification of cell types, tissues and pathways affected by risk loci in psoriasis.
Plasma lactoferrin reflects neutrophil activation in psoriasis.
[Treatment of psoriasis with human leukocyte interferon and interferon combined with deoxyribonuclease and cytostatics (preliminary report)]
Pulmonary Adenomatosis, Ovine
An Investigation of Growth Factors and Lactoferrin in Naturally Occurring Ovine Pulmonary Adenomatosis.
Pulmonary Atelectasis
Bronchoscopic interventions with surfactant and recombinant human deoxyribonuclease for acute respiratory distress syndrome-type respiratory syncytial virus-pneumonia in moderately preterm infants: Case series.
Clinical and in vitro effect of dornase alfa in mechanically ventilated pediatric non-cystic fibrosis patients with atelectases.
DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis.
Dornase alfa (Pulmozyme).
Dornase Alfa for Non-Cystic Fibrosis Pediatric Pulmonary Atelectasis.
Dornase Alpha Compared to Hypertonic Saline for Lung Atelectasis in Critically Ill Patients.
Evaluation of Inhaled Dornase Alfa Administration in Non-Cystic Fibrosis Patients at a Tertiary Academic Medical Center.
Inhaled Dornase alfa (Pulmozyme) as a noninvasive treatment of atelectasis in mechanically ventilated patients.
Lobar atelectasis in cystic fibrosis and treatment with recombinant human DNase I.
Pancreatic dornase aerosol in postoperative atelectasis.
Recombinant human deoxyribonuclease improves atelectasis in mechanically ventilated children with cardiac disease.
Recombinant human deoxyribonuclease shortens ventilation time in young, mechanically ventilated children.
Safety of recombinant human deoxyribonuclease as a rescue treatment for persistent atelectasis in newborns.
Successful treatment of atelectasis with Dornase alpha in a patient with congenital muscular dystrophy.
Successful use of bronchoscopic lung insufflation to treat left lung atelectasis.
The use of dornase alpha for post-operative pulmonary atelectasis after congenital heart surgery.
Treatment of lobar atelectasis with bronchoscopically administered recombinant human deoxyribonuclease in cystic fibrosis?
Pulmonary Disease, Chronic Obstructive
Chronic obstructive pulmonary disease. Mortality and mortality reduction.
Inhaled nebulised unfractionated heparin improves lung function in moderate to very severe COPD: A pilot study.
Lysozyme and lactoferrin in sputum from patients with chronic obstructive lung disease.
Neutrophil extracellular traps promote lipopolysaccharide-induced airway inflammation and mucus hypersecretion in mice.
Plasma protein leakage and local secretion of proteins assessed in sputum in asthma and COPD. The effect of inhaled corticosteroids.
Tear Lipocalin and Lipocalin-Interacting Membrane Receptor.
[Pulmonary medicine. Four major papers in 2010-2011].
Pulmonary Fibrosis
DNaseI Protects against Paraquat-Induced Acute Lung Injury and Pulmonary Fibrosis Mediated by Mitochondrial DNA.
Purpura
[Anti-myeloperoxidase and anti-lactoferrin antibodies in patients with IgA nephropathy and Henoch-Schönlein purpura]
Pyelonephritis
Colicin 24, a new plasmid-borne colicin from a uropathogenic strain of Escherichia coli.
The association between colicinogenicity and pathogenesis among uropathogenic isolates of Escherichia coli.
Virulence profiles, phylogenetic background, and antibiotic resistance of Escherichia coli isolated from turkeys with airsacculitis.
Virulence properties of Escherichia coli strains in patients with chronic pyelonephritis.
Pyometra
Lactoferrin expression in the canine uterus during the estrous cycle and with pyometra.
Lactoferrin in canine sera: a pyometra study.
Pyuria
A prospective observational study of urinary cytokines and inflammatory response in patients with Overactive Bladder Syndrome.
Clinical validation of integrated nucleic acid and protein detection on an electrochemical biosensor array for urinary tract infection diagnosis.
Electrochemical immunosensor detection of urinary lactoferrin in clinical samples for urinary tract infection diagnosis.
Rabies
[An application of desoxyribonuclease in experimental rabies]
[Effect of deoxyribonuclease on rabies virus]
[Study of the mechanism of the action of desoxyribonuclease on rabies virus]
Radicular Cyst
Quantitation of lactoferrin in odontogenic cyst fluids.
Renal Insufficiency
A new mouse model for renal lesions produced by intravenous injection of diphtheria toxin A-chain expression plasmid.
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism.
Development of a radioimmunoassay for human deoxyribonuclease I.
Neutrophil beta(2)-microglobulin and lactoferrin content in renal failure patients.
Protective effect of lactoferrin on Cisplatin-induced nephrotoxicity in rats.
Renal Insufficiency, Chronic
Changes in FGF-23, Neutrophil/Platelet Activation Markers, and Angiogenin in Advanced Chronic Kidney Disease and Their Effect on Arterial Stiffness.
Reperfusion Injury
Effect of DNase I treatment and neutrophil depletion on acute limb ischemia-reperfusion injury in mice.
Oral administration of lactoferrin attenuates intestinal ischemia-reperfusion injury in rats.
Rodent models of AKI-CKD transition.
Reproductive Tract Infections
Lactoferrin in cervical mucus as a biochemical marker for inflammation.
Mucosal lactoferrin response to genital tract infections is associated with iron and nutritional biomarkers in young Burkinabé women.
The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.
Respiratory Distress Syndrome
Consideration of dornase alfa for the treatment of severe COVID-19 acute respiratory distress syndrome.
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.
Iron and iron-related proteins in the lower respiratory tract of patients with acute respiratory distress syndrome.
Signs of neutrophil and eosinophil activation in adult respiratory distress syndrome.
The Use of Dornase Alfa in the Management of COVID-19-Associated Adult Respiratory Distress Syndrome.
Respiratory Insufficiency
Bronchoscopic interventions with surfactant and recombinant human deoxyribonuclease for acute respiratory distress syndrome-type respiratory syncytial virus-pneumonia in moderately preterm infants: Case series.
Identification of transgenic cloned dairy goats harboring human lactoferrin and methylation status of the imprinted gene IGF2R in their lungs.
Respiratory Syncytial Virus Infections
Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection.
Systematic review of the biology and medical management of respiratory syncytial virus infection.
Respiratory Tract Diseases
Backbone and side chain (1)H, (13)C and (15)N resonance assignments of the catalytic domain of diphtheria toxin.
Respiratory Tract Infections
Cow's Milk and Immune Function in the Respiratory Tract: Potential Mechanisms.
Dornase alfa during lower respiratory tract infection post-lung transplantation: a randomized controlled trial.
Dornase alpha inhalations as a treatment option for recurrent lower respiratory tract infections in a child with Sotos syndrome.
Dose effect of bovine lactoferrin fortification on diarrhea and respiratory tract infections in weaned infants with anemia: A randomized, controlled trial.
Effect of bovine lactoferrin from iron-fortified formulas on diarrhea and respiratory tract infections of weaned infants in a randomized controlled trial.
Immune modulation by lactoferrin and curcumin in children with recurrent respiratory infections.
Immunoglobulins and innate factors of immunity in saliva of children prone to respiratory infections.
Interventions for primary (intrinsic) tracheomalacia in children.
Lactoferrin: a potential candidate to fight respiratory infections in the pandemic COVID-19 era.
Preliminary report of in vitro and in vivo effectiveness of dornase alfa on SARS-CoV-2 infection.
Recombinant human DNase in children with airway malacia and lower respiratory tract infection.
Studies of bronchial secretion. The influence of inflammatory response and bacterial infection.
The influence of hydration status during prolonged endurance exercise on salivary antimicrobial proteins.
[Current interest of antipneumococcal vaccination]
[Lactoferrin and respiratory tract infections in infancy]
Reticuloendotheliosis, Avian
Avian reticuloendotheliosis virus (strain T): V. DNA polymerase.
Retinal Detachment
Norrie disease in a family with a manifesting female carrier.
Retinal Vein Occlusion
Higher Aqueous Levels of Resistin and Lipocalin-2 Indicated Worse Visual Improvement following anti-VEGF Therapy in Patients with Retinal Vein Occlusion.
Retinitis
Fomivirsen - a phosphorothioate oligonucleotide for the treatment of CMV retinitis.
Miliary toxoplasmic retinitis in acquired immunodeficiency syndrome.
Retinoblastoma
Carboplatin loaded protein nanoparticles exhibit improve anti-proliferative activity in retinoblastoma cells.
Functional dissection of the promoter of the interphotoreceptor retinoid-binding protein gene: the cone-rod-homeobox element is essential for photoreceptor-specific expression in vivo.
Human lactoferrin controls the level of retinoblastoma protein and its activity.
Lactoferrin increases (172Thr)AMPK phosphorylation and insulin-induced (p473Ser)AKT while impairing adipocyte differentiation.
Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
pRb and CyclinD1 Complement p16 as Immunohistochemical Surrogate Markers of HPV Infection in Head and Neck Cancer.
Proadipogenic effects of lactoferrin in human subcutaneous and visceral preadipocytes.
Retinopathy of Prematurity
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
Lactoferrin Supplementation to Prevent Late-Onset Sepsis in Preterm Infants: A Meta-Analysis.
Protocol for the Lactoferrin Infant Feeding Trial (LIFT): a randomised trial of adding lactoferrin to the feeds of very-low birthweight babies prior to hospital discharge.
Summary Protocol for a Multi-Centre Randomised Controlled Trial of Enteral Lactoferrin Supplementation in Newborn Very Preterm Infants (ELFIN).
Retroviridae Infections
Distribution of xenotropic murine leukemia virus-related virus (XMRV) infection in chronic fatigue syndrome and prostate cancer.
Rhabdomyosarcoma
Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Rhabdomyosarcoma, Alveolar
Regulated expression of the diphtheria toxin A chain by a tumor-specific chimeric transcription factor results in selective toxicity for alveolar rhabdomyosarcoma cells.
Rhabdomyosarcoma, Embryonal
Lactoferrin inhibits enterovirus 71 infection of human embryonal rhabdomyosarcoma cells in vitro.
Rheumatic Diseases
Synovial fluid ferritin, lactoferrin and adenosine deaminase in rheumatic diseases.
[Antibodies to the desoxyribonuclease B of Streptococcus group A in rheumatism]
[Levels of the C 4 component of the complement, lactoferrin and leukocytic thermostabile alpha glycoprotein during the treatment of patients with systemic rheumatic diseases]
Rheumatic Fever
The immunologic response to group A streptococcal upper respiratory tract infections in very young children.
The paradox of the antibody response to streptodornase: the usefulness of antidesoxyribonuclease B as an indication of streptococcal infection in patients with acute rheumatic fever.
[EVALUATION OF THE STREPTOKINASE AND STREPTODORNASE SKIN TEST IN EARLY DIAGNOSIS OF RHEUMATIC FEVER.]
Rheumatoid Vasculitis
Anti-lactoferrin autoantibodies: relation between epitopes and iron-binding domain.
Rhinitis
Pathophysiology of rhinitis. Lactoferrin and lysozyme in nasal secretions.
Rhinitis, Allergic
Lactoferrin administration into the nostril alleviates murine allergic rhinitis and its mechanisms.
Serum lactoferrin level as a serologic biomarker for allergic rhinitis.
Rickettsia Infections
Immunization with a portion of rickettsial outer membrane protein A stimulates protective immunity against spotted fever rickettsiosis.
Rosacea
Tear lactoferrin levels in chronic meibomitis associated with acne rosacea.
Rotavirus Infections
Antirotaviral activity of milk proteins: lactoferrin prevents rotavirus infection in the enterocyte-like cell line HT-29.
Effects of lactoferrin-containing formula in the prevention of enterovirus and rotavirus infection and impact on serum cytokine levels: a randomized trial.
Involvement of bovine lactoferrin metal saturation, sialic acid and protein fragments in the inhibition of rotavirus infection.
Rubella
Isolation and characterization of a new rubella variang with DNA polymerase activity.
Persistent infection of primary human cell cultures with rubella variant carrying DNA Polymerase activity.
Presence of DNA in rubella variant with DNA polymerase activity.
Rubinstein-Taybi Syndrome
Chromosome 16p13.3 Contiguous Gene Deletion Syndrome including the SLX4, DNASE1, TRAP1, and CREBBP Genes Presenting as a Relatively Mild Rubinstein-Taybi Syndrome Phenotype: A Case Report of a Saudi Boy.
Salivary Gland Diseases
Alterations in lactoferrin in salivary gland disease.
Lectin binding studies of parotid salivary glycoproteins in Sjögren's syndrome.
Salmonella Infections
Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal Salmonella.
[Characterization of the biological properties of salmonellae and local immunity in Salmonella infection]
Sarcoidosis, Pulmonary
[Oxygen radical formation in pulmonary sarcoidosis. The signs of early macrophage activation]
Sarcoma
A comparison of the effects of daunomycin and adriamycin on various DNA polymerases.
Antitumor effects of antibody-diphtheria toxin conjugates. II. Immunotherapy with conjugates directed against tumor antigens induced by simian virus 40.
Apparent allosterism by avian myeloblastosis virus reverse transcriptase and E. coli DNA polymerase I.
Biochemical and immunological characterization of Suncus murinus mammary tumor virus DNA polymerase.
Characterization of cells obtained by mechanical and enzymatic means from human melanoma, sarcoma, and lung tumors.
Defective mouse sarcoma virus deficient in DNA polymerase activity.
Deoxyribonuclease I sensitivity of DNA replicated in permeable mouse sarcoma cells.
Differential effects of heparin on replicative DNA synthesis and unscheduled DNA synthesis.
DNASE1L3 as a Prognostic Biomarker Associated with Immune Cell Infiltration in Cancer.
Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.
Inhibition of deoxynucleotide-polymerizing enzyme activities of human leukemia lymphoblasts and simian sarcoma virus by tilorone and thirteen of its analogs.
Inhibition of deoxyribonucleic acid polymerases from human cells and from simian sarcoma virus by pyran.
Inhibition of oncornavirus functions by poly (2-methylthioinosinic acid).
Interruption of oncornavirus replication by modified rifamycin antibiotics.
Mechanism of carcinogenesis by RNA tumor viruses. I. An RNA-dependent DNA polymerase in murine sarcoma viruses.
Mechanixm of Carcinogenesis By RNA Tumor Viruses, I. An RNA-Dependent DNA Polymerase In Murine Sarcoma Viruses.
Moloney murine leukemia virus-induced tumors: recombinant proviruses in active chromatin regions.
Radiation induced breaks increase the priming activity of rat sarcoma DNA in the DNA polymerase reaction.
Reverse transcriptase associated with avian sarcoma-leukosis viruses. I. Comparison of intra-virion content of multiple enzyme forms.
Rifamycin derivatives strongly inhibiting RNA leads to DNA polymerase (reverse transcriptase) of murine sarcoma viruses.
Susceptibility of Rous sarcoma virus-specific sequences integrated into SR-C3H/He mouse ascites sarcoma cell chromatin to DNase I and DNase II.
Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.
[Studies of radiation effects upon the ENA metabolism and desoxyribonuclease activity of rhodamine sarcoma (Umeda).]
Sarcoma 180
Autoradiographic detection of DNA polymerase containing nuclei in sarcoma 180 ascites cells.
Radiolabeled DNase, a potential indicator for noninvasive detection of tissue damage.
Sarcoma, Avian
A DNA-depenent DNA polymerase and a DNA endonuclease in virions of Rous sarcoma virus.
Assay of noninfectious fragments of DNA of avian leukosis virus-infected cells by marker rescue.
At least two nuclear proteins bind specifically to the Rous sarcoma virus long terminal repeat enhancer.
Binding of tryptophanyl-tRNA to the reverse transcriptase of replication-defective avian sarcoma viruses.
Comparative properties of RNA and DNA templates for the DNA polymerase of Rous sarcoma virus.
Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase.
Detection of RNA-instructed DNA polymerase in the mitochondria of Rous sarcoma cells using sephadex G-150 thin-layer gel filtration.
DNA polymerase activity from two temperature-sensitive mutants of Rous sarcoma virus is thermolabile.
DNA polymerase in defective Rous sarcoma virus.
Effect of transformation by Rous sarcoma virus on the character and distribution of actin in Rat-1 fibroblasts: a biochemical and microscopical study.
Efficeint transcription of RNA into DNA by avian sarcoma virus polymerase.
Endogenous DNA polymerase of a transformation-defective rous sarcoma virus: characterization and comparison with the enzyme of the non-defective parent.
Extensive in vitro transcription of rous sarcoma virus RNA by avian myeloblastosis virus DNA polymerase and concurrent activation of the associated RNase H.
In vitro synthesis of full-length DNA transcripts of Rous sarcoma virus RNA by viral DNA polymerase.
In vitro translation of a 180,000-dalton Rous sarcoma virus precursor polypeptide containing both the DNA polymerase and the group-specific antigens.
Infectious DNA coding for a temperature-sensitive DNA polymerase of the coordinate LA335 mutant of Rous sarcoma virus (RSV).
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide.
Marker rescue of endogenous cellular genetic information related to the avian leukosis virus gene encoding RNA-directed DNA polymerase.
Mechanism of transfection of chicken embryo fibroblasts by Rous sarcoma virus DNA.
New procedure for the direct analysis of in vitro reverse transcription of Rous sarcoma virus RNA.
On the fidelity of DNA replication. Enzyme activities associated with DNA polymerases from RNA tumor viruses.
Preferential inhibition of growth and protein synthesis in Rous sarcoma virus transformed cells by diphtheria toxin.
Properties of a soluble DNA polymerase isolated from Rous sarcoma virus.
Recombinant reverse transcriptase of Rous sarcoma virus: characterization of DNA polymerase and RNAase H activities.
Reverse transcriptase as the major determinant for selective packaging of tRNA's into Avian sarcoma virus particles.
RNA-dependent DNA polymerase of avian sarcoma virus B77. I. Isolation and partial characterization of the alpha, beta2, and alphabeta forms of the enzyme.
RNA-directed DNA polymerase activity of reticuloendotheliosis virus: characterization of the endogenous and exogenous reactions.
RNA-directed DNA synthesis by the DNA polymerase of Rous sarcoma virus: structural and functional identification of 4S primer RNA in uninfected cells.
RNAase-sensitive DNA-dependent DNA polymerase from rat cells transformed by avian sarcoma virus.
Rous sarcoma virus genome is terminally redundant: the 3' sequence.
Specificities involved in the initiation of retroviral plus-strand DNA.
Susceptibility of Rous sarcoma virus-specific sequences integrated into SR-C3H/He mouse ascites sarcoma cell chromatin to DNase I and DNase II.
Temperature-sensitive DNA polymerase from Rous sarcoma virus mutants.
Terminal redundancy and the origin of replication of Rous sarcoma virus RNA.
The beta subunit of the DNA polymerase of avian sarcoma virus strain B77 is a phosphoprotein.
Unintegrated viral DNA is synthesized in the cytoplasm of avian sarcoma virus-transformed duck cells by viral DNA polymerase.
Virus-coded DNA endonuclease from avian retrovirus.
[Recombinant reverse transcriptase from Rous sarcoma virus. Kinetics and inhibition of DNA polymerase activity]
Sarcoma, Kaposi
Human Kaposi's sarcoma herpesvirus processivity factor-8 functions as a dimer in DNA synthesis.
Sarcoma, Yoshida
DNA synthesis in tumor-bearing rats.
Intracellular distribution of various enzymes concerned with DNA synthesis from normal and regenerating rat liver, and Yoshida sarcoma.
Metabolism of 5-fluorouracil in sensitive and resistant tumor cells.
Scabies
Regulation and secretion of an extracellular esterase from Streptomyces scabies.
Second internal transcribed spacer (ITS-2) as genetic marker for molecular characterization of Sarcoptes scabiei in rabbits from several areas of East Java, Indonesia.
Scleroderma, Systemic
Association of the DNASE1L3 rs35677470 polymorphism with systemic lupus erythematosus, rheumatoid arthritis and systemic sclerosis: Structural biological insights.
Salivary: flow and proteins of the innate and adaptive immunity in the limited and diffused systemic sclerosis.
Scrapie
Inactivation of the scrapie agent by pronase.
Properties of the scrapie agent-endomembrane complex from hamster brain.
Seizures
Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression.
Seminoma
Expression of terminal deoxynucleotidyl transferase (TdT) in classical seminoma: a potential diagnostic pitfall.
[Mechanism of p53 gene mutation in the development of urologic cancer]
Sepsis
A high-throughput method for the quantification of iron saturation in lactoferrin preparations.
Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis.
Antimicrobial Functions of Lactoferrin Promote Genetic Conflicts in Ancient Primates and Modern Humans.
Antimicrobial Peptides in Human Sepsis.
Bioinspired DNase-I-Coated Melanin-Like Nanospheres for Modulation of Infection-Associated NETosis Dysregulation.
Bovine lactoferrin appears to decrease the incidence of sepsis in very low-birth weight infants.
Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial.
Bovine Lactoferrin Supplementation for Prevention of Late-onset Sepsis in very Low-Birth-Weight Neonates.
Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial.
Bovine Lactoferrin to Prevent Neonatal Infections in Low-Birth-Weight Newborns in Pakistan: Protocol for a Three-Arm Double-Blind Randomized Controlled Trial.
Can lactoferrin prevent neonatal sepsis and necrotizing enterocolitis?
Characterization of Escherichia coli serogroups causing meningitis, sepsis and enteritis. II. Classification of Escherichia coli O78 strains by phage sensitivity, colicin type and antibiotic resistance.
Colicin V production by clinical isolates of Escherichia coli.
Commentary on "Enteral Lactoferrin Supplementation for Prevention of Sepsis and Necrotizing Enterocolitis in Preterm Infants".
Comparative evaluation of pulmonary lactoferrin and lysozyme immunoreactivity for the postmortem diagnosis of death due to sepsis.
Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis.
Dietary Bovine Lactoferrin Increases Resistance of Juvenile Channel Catfish, Ictalurus punctatus, to Enteric Septicemia
Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice.
Dose Escalation Study of Bovine Lactoferrin in Preterm Infants: Getting the Dose Right.
Early Dynamics of Plasma DNA in a Mouse Model of Sepsis.
Early fall of circulating iron and rapid rise of lactoferrin in septicemia and endotoxemia: an early defence mechanism.
Early optimal nutrition improves neurodevelopmental outcomes for very preterm infants.
Early response in neonatal septicemia. The effect of Escherichia coli, Streptococcus agalactiae and tumor necrosis factor on the generation of lactoferrin.
Early response in septicemia in newborns and their mothers. Effect of Escherichia coli, Streptococcus agalactiae and tumor necrosis factor on lactoferrin release and the generation of tissue thromboplastin.
Effect of bovine lactoferrin as a novel therapeutic agent in a rat model of sepsis-induced acute lung injury.
Effect of bovine lactoferrin on prevention of late-onset sepsis in infants <1500g: a pooled analysis of individual patient data from two randomized controlled trials.
Efficacy of Bovine Lactoferrin Supplementation in Preventing Late-onset Sepsis in low Birth Weight Neonates: A Randomized Placebo-Controlled Clinical Trial.
Elevated circulating E-selectin, intercellular adhesion molecule 1, and von Willebrand factor in patients with severe infection.
Elevated plasma levels of antimicrobial polypeptides in patients with severe sepsis.
ELFIN, the United Kingdom preterm lactoferrin trial: interpretation and future questions.
Enhancement of the antimicrobial activity and selectivity of GNU7 against Gram-negative bacteria by fusion with LPS-targeting peptide.
Enteral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.
Evaluation of serotypes 5 and 8 capsular polysaccharides in protection against Staphylococcus aureus in murine models of infection.
Evidence from systematic reviews of randomized trials on enteral lactoferrin supplementation in preterm neonates.
Exogenous deoxyribonuclease has a protective effect in a mouse model of sepsis.
Exposure to Gastric Acid Inhibitors Increases the Risk of Infection in Preterm Very Low Birth Weight Infants but Concomitant Administration of Lactoferrin Counteracts This Effect.
Feasibility of a Novel Approach for Rapid Detection of Simulated Bloodstream Infections via Enzymatic Template Generation and Amplification (ETGA)-Mediated Measurement of Microbial DNA Polymerase Activity.
Host DNases prevent vascular occlusion by neutrophil extracellular traps.
Human recombinant lactoferrin for sepsis: too good to be true?*.
Interleukin-6, C-reactive protein, lactoferrin and white blood cell count in patients with S. aureus septicemia.
Is Lactoferrin More Effective in Reducing Late-Onset Sepsis in Preterm Neonates Fed Formula Than in Those Receiving Mother's Own Milk? Secondary Analyses of Two Multicenter Randomized Controlled Trials.
Klebsiella pneumoniae Peptidoglycan-Associated Lipoprotein and Murein Lipoprotein Contribute to Serum Resistance, Antiphagocytosis, and Proinflammatory Cytokine Stimulation.
Lactoferrin and prevention of late-onset sepsis in the pre-term neonates.
Lactoferrin as an indicator of septicemia and endotoxemia in pigs.
Lactoferrin effects on the in vitro immune response in critically ill patients.
Lactoferrin Expression Is Not Associated with Late-Onset Sepsis in Very Preterm Infants.
Lactoferrin for prevention of neonatal infections.
Lactoferrin inhibits the lipopolysaccharide-induced expression and proteoglycan-binding ability of interleukin-8 in human endothelial cells.
Lactoferrin reduces mortality in preweaned calves with diarrhea.
Lactoferrin serum levels in burned patients.
Lactoferrin Supplementation to Prevent Late-Onset Sepsis in Preterm Infants: A Meta-Analysis.
Lactoferrin: A Critical Player in Neonatal Host Defense.
Lactoferrin: a multifunctional glycoprotein involved in the modulation of the inflammatory process.
Late-onset sepsis in preterm infants: update on strategies for therapy and prevention.
Management of Intrapleural Sepsis with Once Daily Use of Tissue Plasminogen Activator and Deoxyribonuclease.
Mechanistic Studies of Dnase I Activity: Impact of Heparin Variants and PAD4.
Neonatal sepsis: new preventive strategies.
Neutrophil activation in acute renal failure and sepsis.
Nutrition in the preterm infant: what’s new?
Nutritional interventions to reduce rates of infection, necrotizing enterocolitis and mortality in very preterm infants.
Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants.
Oral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates.
Oral Lactoferrin to Prevent Nosocomial Sepsis and Necrotizing Enterocolitis of Premature Neonates and Effect on T-Regulatory Cells.
Outer membrane protein A (OmpA), peptidoglycan-associated lipoprotein (PAL), and murein lipoprotein (MLP) are released in experimental Gram-negative sepsis.
Plasma concentrations of defensins and lactoferrin in children with severe sepsis.
Plasma elastase alpha 1-antitrypsin and lactoferrin in sepsis: evidence for neutrophils as mediators in fatal sepsis.
Plasma lactoferrin levels in newborn preterm infants with sepsis.
Preventing necrotizing enterocolitis by food additives in neonates: A network meta-analysis revealing the efficacy and safety.
Progress in the field of necrotising enterocolitis - year 2012.
Prophylactic lactoferrin for preventing late-onset sepsis and necrotizing enterocolitis in preterm infants: A PRISMA-compliant systematic review and meta-analysis.
Protocol for the Lactoferrin Infant Feeding Trial (LIFT): a randomised trial of adding lactoferrin to the feeds of very-low birthweight babies prior to hospital discharge.
Randomized Controlled Trial of Bovine Lactoferrin for Prevention of Sepsis and Neurodevelopment Impairment in Infants Weighing Less Than 2000 Grams.
Randomized controlled trial of lactoferrin for prevention of sepsis in peruvian neonates less than 2500 g.
Rapid Rule Out of Culture-Negative Bloodstream Infections by Use of a Novel Approach to Universal Detection of Bacteria and Fungi.
Recent advances in prevention of sepsis in the premature neonates in NICU.
Rethinking the Doses of Tissue Plasminogen Activator and Deoxyribonuclease Administrated Concurrently for Intrapleural Therapy for Complicated Pleural Effusion and Empyema.
Retrospective analysis of clinical data associated with patients enrolled in a molecular diagnostic feasibility study highlights the potential utility for rapid detection of bloodstream infection.
Role of Lactoferrin in Neonates and Infants: An Update.
Serum lactoferrin and immunoglobulin G concentrations in healthy or ill neonatal foals and healthy adult horses.
Severe Pulmonary Hemorrhage in a Neonate With Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation.
Synbiotic use for the prevention of sepsis and necrotizing enterocolitis in very low birth weight neonates: a randomized controlled trial.
Taurine chloramine selectively regulates neutrophil degranulation through the inhibition of myeloperoxidase and upregulation of lactoferrin.
The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial.
The impact of lactoferrin with different levels of metal saturation on the intestinal epithelial barrier function and mucosal inflammation.
The impact of probiotics and lactoferrin supplementation on piglet gastrointestinal microbial communities.
The latency of serum acute phase proteins in meningococcal septicemia, with special emphasis on lactoferrin.
The non-immune inflammatory response: serial changes in plasma iron, iron-binding capacity, lactoferrin, ferritin and C-reactive protein.
The Role of Lactoferrin in Gastrointestinal and Immune Development and Function: A Preclinical Perspective.
Use of lactoferrin in the newborn: where do we stand?
Virulence factors associated with F165-positive Escherichia coli strains isolated from piglets and calves.
[A new approach to clinical and laboratory diagnosis of systemic and local soft tissue infections]
[Clinical significance of inflammation markers in abdominal sepsis patients]
[Determination of the concentration of C-reactive protein, oligopeptides and lactoferrin of blood as a method of early diagnosis of mesenchymal sepsis]
[Elastase-alpha 1-proteinase inhibitor complex (E alpha 1 PI) and lactoferrin plasma concentrations in viral and bacterial infections]
[Recent advances in prevention of sepsis in the preterm neonate].
[The role of lactoferrin in the iron metabolism. Part II. Antimicrobial and antiinflammatory effect of lactoferrin by chelation of iron].
[The use of plasma lactoferrin in the diagnosis of pyonecrotic infections of soft tissues and sepsis]
Severe Acute Respiratory Syndrome
Inhibition of SARS pseudovirus cell entry by lactoferrin binding to heparan sulfate proteoglycans.
The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria.
The Prospect of Lactoferrin Use as Adjunctive Agent in Management of SARS-CoV-2 Patients: A Randomized Pilot Study.
Therapeutic Effects of Lactoferrin in Ocular Diseases: From Dry Eye Disease to Infections.
Severe Combined Immunodeficiency
Fc-dependent polyclonal antibodies and antibodies to outer membrane proteins A and B, but not to lipopolysaccharide, protect SCID mice against fatal Rickettsia conorii infection.
Sexually Transmitted Diseases
Antimicrobial peptides of the vaginal innate immunity and their role in the fight against sexually transmitted diseases.
Evaluation of the reproductive toxicity of antiretroviral drug loaded lactoferrin nanoparticles.
Shock, Cardiogenic
[The reactants of acute phase of inflammation and anti-inflammatory cytokines under various complications of cardiac infarction].
Shock, Septic
Antimicrobial and immunoregulatory functions of lactoferrin and its potential therapeutic application.
Bovine colostrum in oral treatment of enterogenic endotoxaemia in rats.
Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex.
Lactoferrin and host defence: an overview of its immuno-modulating and anti-inflammatory properties.
Lactoferrin: a modulator of immune and inflammatory responses.
Tumor necrosis factor-?-induced inflammatory responses in cattle
Tumor necrosis factor-?-induced inflammatory responses in cattle.
Sialadenitis
Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva.
Immunohistochemical study of palatal salivary glands of denture wearing patients.
Siderosis
Elevated CSF lactoferrin in superficial siderosis of the central nervous system.
Sinusitis
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.
Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis.
Lysozyme and lactoferrin in human maxillary sinus mucosa during chronic sinusitis. An immunohistochemical study.
Nasal mucosa expression of lactoferrin in patients with chronic rhinosinusitis.
Nasally inhaled dornase alfa in the postoperative management of chronic sinusitis due to cystic fibrosis.
[Lysozyme and lactoferrin in human uncinate process mucosa during chronic sinusitis]
Situs Inversus
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome.
Sjogren's Syndrome
Lactoferrin suppresses loss of corneal epithelial integrity in a rabbit short-term dry eye model.
Minor gland saliva flow rate and proteins in subjects with hyposalivation due to Sjogren's syndrome and radiation therapy.
Skin Diseases
Acute skin eruptions that are positive for herpes simplex virus DNA polymerase in patients with stem cell transplantation: a new manifestation within the erythema multiforme reactive dermatoses.
Skin Neoplasms
Development of quantitative DNA cleavage assay for XPG endonuclease activity using endogenous nuclear proteins in human cell lines.
DNA polymerase ? mutational signatures are found in a variety of different types of cancer.
Effects of Active Site Mutations on Specificity of Nucleobase Binding in Human DNA Polymerase ?.
Error-Prone Replication through UV Lesions by DNA Polymerase ? Protects against Skin Cancers.
Low fidelity DNA synthesis by human DNA polymerase-eta.
Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H.
Relative Binding Free Energies of Adenine and Guanine to Damaged and Undamaged DNA in Human DNA Polymerase ?: Clues for Fidelity and Overall Efficiency.
The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells.
Translesion Synthesis by DNA Polymerase ? Protects from Skin Cancers.
UV-induced mutations in epidermal cells of mice defective in DNA polymerase ? and/or ?
Xeroderma pigmentosum variant and error-prone DNA polymerases.
Xeroderma pigmentosum variant: Complementary molecular approaches to detect a 13 base pair deletion in the DNA polymerase eta gene.
Smallpox
Detection of monkeypox virus with real-time PCR assays.
Looking back at smallpox.
Orthopoxvirus DNA: a comparison of restriction profiles and maps.
The relation of the DNA polymerase to an early temperature-sensitive event in the replication of variola virus.
Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives.
Soft Tissue Infections
Colicin insensitivity correlates with higher prevalence of extraintestinal virulence factors among Escherichia coli isolates from skin and soft-tissue infections.
[A new approach to clinical and laboratory diagnosis of systemic and local soft tissue infections]
[The use of plasma lactoferrin in the diagnosis of pyonecrotic infections of soft tissues and sepsis]
Sotos Syndrome
Dornase alpha inhalations as a treatment option for recurrent lower respiratory tract infections in a child with Sotos syndrome.
Spermatic Cord Torsion
Degradation of Extracellular DNA by DNase1 Significantly Reduces Testicular Damage After Testicular Torsion in Rats.
Spina Bifida Cystica
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure.
Spinal Cord Diseases
[A study of free radical defense and oxidative stress in the sera of patients with neuroimmunological disorders]
Spinal Cord Injuries
Elevated serum lactoferrin and neopterin are associated with postoperative infectious complications in patients with acute traumatic spinal cord injury.
Spondylarthropathies
Cytidine deaminase and lactoferrin in inflammatory synovial fluids. Indicators of local polymorphonuclear cell function?
Recombinant Salmonella typhimurium outer membrane protein A is recognized by synovial fluid CD8 cells and stimulates synovial fluid mononuclear cells to produce interleukin (IL)-17/IL-23 in patients with reactive arthritis and undifferentiated spondyloarthropathy.
Spondylitis
[Eikenella corrodens-induced spondylitis. Detection with 16s-RNA polymerase chain reaction]
Spondylitis, Ankylosing
Anti-lactoferrin antibodies and other types of anti-neutrophil cytoplasmic antibodies (ANCA) in reactive arthritis and ankylosing spondylitis.
Serum Deoxyribonuclease 1-like 3 is a potential biomarker for diagnosis of ankylosing spondylitis.
[Correlation of DNase I in serum and synovial fluid with inflammatory activity in patients with rheumatoid arthritis].
Sporotrichosis
[Presence of lactoferrin (LF) in lymphocutaneous sporotrichosis. Yeast-bound antimicrobial peptide].
Spotted Fever Group Rickettsiosis
A snapshot of the microbiome of Amblyomma tuberculatum ticks infesting the gopher tortoise, an endangered species.
A survey for spotted fever group rickettsiae and ehrlichiae in Amblyomma variegatum from St. Kitts and Nevis.
Genotypic and antigenic identification of two new strains of spotted fever group rickettsiae isolated from China.
Immunization with a portion of rickettsial outer membrane protein A stimulates protective immunity against spotted fever rickettsiosis.
Isolation of a spotted fever group Rickettsia, Rickettsia peacockii, in a Rocky Mountain wood tick, Dermacentor andersoni, cell line.
Possible Case of Novel Spotted Fever Group Rickettsiosis in Traveler Returning to Japan from India.
Rickettsia felis from cat fleas: isolation and culture in a tick-derived cell line.
Rickettsia monacensis sp. nov., a spotted fever group Rickettsia, from ticks (Ixodes ricinus) collected in a European city park.
Short report: Rickettsia felis outer membrane protein A: a potential tool for diagnosis of patients with flea-borne spotted fever.
Spotted fever group rickettsiae in ticks from the Masai Mara region of Kenya.
Using PCR/RFLP to detect spotted fever group rickettsia in ticks and rodents collected in Ninghua, Fujian province.
Squamous Cell Carcinoma of Head and Neck
Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas.
Bovine lactoferrin reverses programming of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition in oral squamous cell carcinoma.
Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase ? and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma.
Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma.
Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo.
pRb and CyclinD1 Complement p16 as Immunohistochemical Surrogate Markers of HPV Infection in Head and Neck Cancer.
Serum alkaline deoxyribonuclease in oral cancer and premalignant lesions.
The cytotoxic effects of human neutrophil peptide-1 (HNP1) and lactoferrin on oral squamous cell carcinoma (OSCC) in vitro.
[Relationship between tumor cell proliferating activity and biological behavior, prognosis in laryngeal carcinoma]
ST Elevation Myocardial Infarction
Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction.
Staphylococcal Infections
Dietary Bovine Lactoferrin Reduces Staphylococcus aureus in the Tissues and Modulates the Immune Response in Piglets Systemically Infected with S. aureus.
Influence of lactoferrin feeding and injection against systemic staphylococcal infections in mice.
Optimizing treatment policies and improving care: impact on outcome in patients with cystic fibrosis.
Various routes of administration of (99m)Tc-labeled synthetic lactoferrin antimicrobial peptide hLF 1-11 enables monitoring and effective killing of multidrug-resistant Staphylococcus aureus infections in mice.
Starvation
A cka-gfp transcriptional fusion reveals that the colicin K activity gene is induced in only 3 percent of the population.
Amino acid starvation and colicin D treatment induce A-site mRNA cleavage in Escherichia coli.
Antagonistic functions between the RNA chaperone Hfq and an sRNA regulate sensitivity to the antibiotic colicin.
Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation.
Autophagy determines mtDNA copy number dynamics during starvation.
Cell transformation by c-Ha-rasVal12 oncogene is accompanied by a decrease in histone H1 zero and an increase in nucleosomal repeat length.
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1.
Defining the DNA Binding Site Recognized by the Fission Yeast Zn2Cys6 Transcription Factor Pho7 and Its Role in Phosphate Homeostasis.
Effect of starvation on susceptibility of rat liver nuclei to DNase I.
Expression of DNase I in rat parotid gland and small intestine is regulated by starvation and refeeding.
Extracellular manganese-stimulated deoxyribonuclease as a marker event in sporulation of Bacillus subtilis.
Functional activity of DNA and DNA polymerase during thymine starvation of Escherichia coli 15T.
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism.
Haemophilus influenzae can use human transferrin as a sole source for required iron.
Heterogeneity in expression of the Escherichia coli colicin K activity gene cka is controlled by the SOS system and stochastic factors.
Investigation of antibacterial mechanism and identification of bacterial protein targets mediated by antibacterial medicinal plant extracts.
Large-scale organization of ribosomal DNA chromatin is regulated by Tip5.
Overexpression of initiation factor eIF-4E does not relieve the translational repression of ribosomal protein mRNAs in quiescent cells.
Oxidative DNA damage defense systems in avoidance of stationary-phase mutagenesis in Pseudomonas putida.
Regulation of gastric mucosal DNA synthesis during fasting and refeeding in rats.
The Transcription Factor ZafA Regulates the Homeostatic and Adaptive Response to Zinc Starvation in Aspergillus fumigatus.
Stomach Neoplasms
A Point Mutation in DNA Polymerase ? (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer.
Anticancer Effect of Enterocin A-Colicin E1 Fusion Peptide on the Gastric Cancer Cell.
Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin.
Blockade of ?-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration.
Bovine lactoferricin B induces apoptosis of human gastric cancer cell line AGS by inhibition of autophagy at a late stage.
Circulating DNA and DNase activity in human blood.
Copper or Magnesium Supplementation Endows the Peptic Hydrolysate from Bovine Lactoferrin with Enhanced Activity to Human Gastric Cancer AGS Cells.
Crosstalk between mismatch repair and base excision repair in human gastric cancer.
Destruction of Neutrophil Extracellular Traps Promotes the Apoptosis and Inhibits the Invasion of Gastric Cancer Cells by Regulating the Expression of Bcl-2, Bax and NF-?B.
Effect of Cu/Mn-Fortification on In Vitro Activities of the Peptic Hydrolysate of Bovine Lactoferrin against Human Gastric Cancer BGC-823 Cells.
Highly sensitive nuclease assays based on chemically modified DNA or RNA.
Low density neutrophils (LDN) in postoperative abdominal cavity assist the peritoneal recurrence through the production of neutrophil extracellular traps (NETs).
Pyrimidine nucleotide synthesis is more extensive in poorly differentiated than in well-differentiated human gastric carcinoma.
The DNA Endonuclease Mus81 Regulates ZEB1 Expression and Serves as a Target of BET4 Inhibitors in Gastric Cancer.
Stomatitis
A Comparison of Parapoxviruses in North American Pinnipeds.
Bovine lactoferrin and piroxicam as an adjunct treatment for lymphocytic-plasmacytic gingivitis stomatitis in cats.
Evaluation of bovine lactoferrin as a topical therapy for chemotherapy-induced mucositis in the golden Syrian hamster.
Granulocyte macrophage-colony stimulating factor (GM-CSF) and sucralfate in prevention of radiation-induced mucositis: a prospective randomized study.
Oral administration of bovine lactoferrin for treatment of intractable stomatitis in feline immunodeficiency virus (FIV)-positive and FIV-negative cats.
[Inhibition of 5-fluorouracil-cisplatin-induced stomatitis by oral cryotherapy: use of an ice-bar containing fibrinolysin and deoxyribonuclease combine (Elase)]
Streptococcal Infections
Acute rheumatic fever in a patient with glycogen storage disease type Ib: causal or coincidental simultaneous occurrence?
Lactoferrin: A Critical Mediator of Both Host Immune Response and Antimicrobial Activity in Response to Streptococcal Infections.
Poststreptococcal reactive arthritis.
The immunologic response to group A streptococcal upper respiratory tract infections in very young children.
The paradox of the antibody response to streptodornase: the usefulness of antidesoxyribonuclease B as an indication of streptococcal infection in patients with acute rheumatic fever.
[Interest of stimultaneous determination of antistreptolysins and antideoxyribonuclease B in streptococcal infections (author's transl)]
Stroke
HDAC9, TWIST1 and FERD3L gene expression in asymptomatic stable and unstable carotid plaques.
Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model.
Investigation and comparison of the protective activities of three functional proteins-lactoferrin, ?-lactalbumin, and ?-lactoglobulin-in cerebral ischemia reperfusion injury.
Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke.
Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance.
The effects of lactoferrin in a rat model of catecholamine cardiotoxicity.
Whey Protein and Its Components Lactalbumin and Lactoferrin Affect Energy Balance and Protect against Stroke Onset and Renal Damage in Salt-Loaded, High-Fat Fed Male Spontaneously Hypertensive Stroke-Prone Rats.
Subacute Sclerosing Panencephalitis
HN glycoprotein of HVJ (Sendai virus) enhances the selective cytotoxicity of diphtheria toxin fragment A-containing liposomes on subacute sclerosing panencephalitis virus-infected cells.
Selective killing of subacute sclerosing panencephalitis virus-infected cells by liposomes containing fragment A of diphtheria toxin.
Sunburn
Premature keratinocyte death and expression of marker proteins of apoptosis in human skin after UVB exposure.
Superinfection
Enhancement of herpes simplex virus type 2 (HSV-2) DNA synthesis in infected cells that constitutively express the BglII-N region of the HSV-2 genome.
Induction of DNA polymerase activity after superinfection of Raji cells with Epstein-Barr virus.
Interactions between de-repressed F-like R factors and wild type colicin B factors: superinfection immunity and repressor susceptibility.
Plasma lactoferrin content: differential effect of steroid administration and infective illnesses: lack of effect of ambient temperature at which specimens are collected.
Synovitis
Antineutrophil cytoplasmic antibodies in synovial fluid and in serum of patients with rheumatoid arthritis and other types of synovitis.
Increased levels of lactoferrin in synovial fluid but not in serum from patients with rheumatoid arthritis.
Syphilis
Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
Destructive osteomyelitis associated with early secondary syphilis in an HIV-positive patient diagnosed by Treponema pallidum DNA polymerase chain reaction.
Systemic Vasculitis
Autoantibodies to lactoferrin and histone in systemic vasculitis identified by anti-myeloperoxidase solid phase assays.
[Levels of the C 4 component of the complement, lactoferrin and leukocytic thermostabile alpha glycoprotein during the treatment of patients with systemic rheumatic diseases]
Tachycardia
[The Churg-Strauss syndrome]
Tauopathies
Iron and Alzheimer's Disease: From Pathogenesis to Therapeutic Implications.
Telangiectasis
ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress.
Teratocarcinoma
Actin pools in extracts of teratocarcinoma cells, assayed by inhibition of DNase I.
Alkaline deoxyribonuclease activity in mouse teratocarcinoma cells: variation of enzyme levels during differentiation.
Changes in the conformation of the interferon beta gene during differentiation and induction.
Control of expression of histocompatibility antigens (H-2) and beta 2-microglobulin in F9 teratocarcinoma stem cells.
Immunofluorescence studies on deoxyribonuclease from mouse teratocarcinoma cells during cell differentiation.
Tetanus
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex.
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens.
A physico-chemical assessment of the thermal stability of pneumococcal conjugate vaccine components.
A randomized, multicenter, open-label clinical trial to assess the immunogenicity of a meningococcal C vaccine booster dose administered to children aged 14 to 18 months.
A routine high-performance size-exclusion chromatography to determine molecular size distribution of Haemophilus influenzae type b conjugate vaccines.
A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons.
Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.
Adjuvant Allergen Fusion Proteins as Novel Tools for the Treatment of Type I Allergies.
Adoptive immunotherapy in canine chimeras.
An olfactory circuit increases the fidelity of visual behavior.
Antibody microarrays for native toxin detection.
Antibody Responses After Primary Immunization in Infants Born to Women Receiving a Pertussis-containing Vaccine During Pregnancy: Single Arm Observational Study With a Historical Comparator.
Antibody responses elicited by a polyvalent vaccine containing synthetic diphtheric, streptococcal and hepatitis peptides coupled to the same carrier.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Antibody responses to Bordetella pertussis and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy- a prospective, observational cohort study from the UK.
Avian eyelid assay, a new diagnostic method for detecting botulinum neurotoxin serotypes A, B and E.
Avidity and bactericidal activity of antibody elicited by different Haemophilus influenzae type b conjugate vaccines. The Vaccine Study Group.
Biological and immunological characteristics of lipooligosaccharide-based conjugate vaccines for serotype C Moraxella catarrhalis.
Capture EIA for determination of IgE to diphtheria and tetanus toxins in comparison to RIA.
Carrier priming with CRM 197 or diphtheria toxoid has a different impact on the immunogenicity of the respective glycoconjugates: biophysical and immunochemical interpretation.
Cellular identification of water gustatory receptor neurons and their central projection pattern in Drosophila.
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.
Characterization of production processes for tetanus and diphtheria anatoxins.
Combination of DTP and Haemophilus influenzae type b conjugate vaccines can affect laboratory evaluation of potency and immunogenicity.
Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age.
Comparison of carrier proteins to conjugate malaria transmission blocking vaccine antigens, Pfs25 and Pfs230.
Comparison of CRM197, diphtheria toxoid and tetanus toxoid as protein carriers for meningococcal glycoconjugate vaccines.
Concomitant administration of diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) with pentavalent rotavirus vaccine in Japanese infants.
Determination of free polysaccharide in Vi glycoconjugate vaccine against typhoid fever.
Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus.
Development of Vi conjugate - a new generation of typhoid vaccine.
Differences in the avidity of antibodies evoked by four different pneumococcal conjugate vaccines in early childhood.
Differential potencies of effector genes in adult Drosophila.
Diphtheria, tetanus and pertussis antibodies in 10-year-old children before and after a booster dose of three toxoids: implications for the timing of a booster dose.
Discovery of novel bacterial toxins by genomics and computational biology.
Dose response of CRM197 and tetanus toxoid-conjugated Haemophilus influenzae type b vaccines.
Effect of carrier protein priming on antibody responses to Haemophilus influenzae type b conjugate vaccines in infants.
Effect of vaccination with carrier protein on response to meningococcal C conjugate vaccines and value of different immunoassays as predictors of protection.
Effects of feeding probiotics during weaning on infections and antibody responses to diphtheria, tetanus and Hib vaccines.
Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers.
Enhanced antibody responses in infants given different sequences of heterogeneous Haemophilus influenzae type b conjugate vaccines.
Enhancement of cellular protein synthesis sensitivity to diphtheria toxin by interferon.
Enhancement of diphtheria toxin potency by replacement of the receptor binding domain with tetanus toxin C-fragment: a potential vector for delivering heterologous proteins to neurons.
Evaluation of Critical Quality Attributes of a Pentavalent (A, C, Y, W, X) Meningococcal Conjugate Vaccine for Global Use.
Evaluation of single- and dual antigen delayed fluorescence immunoassay in comparison to an ELISA and the in vivo toxin neutralisation test for detection of diphtheria toxin antibodies.
Expression and purification of a trivalent pertussis toxin-diphtheria toxin-tetanus toxin fusion protein in Escherichia coli.
Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain.
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.
Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens.
Fifth vaccination with dipthteria, tetanus and acellular pertussis is beneficial in four- to six-year-olds.
Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.
Generation of plant-derived recombinant DTP subunit vaccine.
Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
Glycoconjugate vaccines and immune interference: A review.
Haemophilus influenzae type b conjugate vaccines: a review of efficacy data.
Humoral and cell mediated immune responses to a pertussis containing vaccine in pregnant and nonpregnant women.
Hybrid tetanus toxin C fragment-diphtheria toxin translocation domain allows specific gene transfer into PC12 cells.
Identification of Conformational B-cell Epitopes in Diphtheria Toxin at Varying Temperatures Using Molecular Dynamics Simulations.
IgG subclass distribution of antibodies after vaccination of adults with pneumococcal conjugate vaccines.
Immunodeficiency in alpha-mannosidosis: a matched case-control study on immunoglobulins, complement factors, receptor density, phagocytosis and intracellular killing in leucocytes.
Immunogenicity of a Single Dose of Meningococcal Group C Conjugate Vaccine Given at 3 Months of Age to Healthy Infants in the United Kingdom.
Immunogenicity of Haemophilus influenzae type b conjugate vaccines in infant rhesus monkeys.
Immunogenicity of meningococcal B polysaccharide conjugated to tetanus toxoid or CRM197 via adipic acid dihydrazide.
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Induction of immunologic memory in infants primed with Haemophilus influenzae type b conjugate vaccines.
Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.
Infant antibody levels following 10-valent pneumococcal-protein D conjugate and DTaP-Hib vaccinations in the first year of life after maternal Tdap vaccination: An open-label, parallel, randomised controlled trial.
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
Interactions of conjugate vaccines and co-administered vaccines.
Isolation and characterization of new human carrier peptides from two important vaccine immunogens.
Long-term antibody persistence after a booster dose of quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine in healthy 5-year-old children.
Low pH induces a hydrophobic domain in the tetanus toxin molecule.
Measuring immunoglobulin g antibodies to tetanus toxin, diphtheria toxin, and pertussis toxin with single-antigen enzyme-linked immunosorbent assays and a bead-based multiplex assay.
Mosquito inoculation: an alternative bioassay for toxins.
Multi-epitope insert modulates solubility-based and chromatographic purification of human papilloma virus 16 L1-based vaccine without inhibiting virus-like particle assembly.
Multiplexed measurement of serum antibodies using an array biosensor.
Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach.
Oral immunogenicity of tomato-derived sDPT polypeptide containing Corynebacterium diphtheriae, Bordetella pertussis and Clostridium tetani exotoxin epitopes.
Patterns of binding of aluminum-containing adjuvants to Haemophilus influenzae type b and meningococcal group C conjugate vaccines and components.
Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates.
Preclinical studies on new proteins as carrier for glycoconjugate vaccines.
Randomized clinical trial of DTaP5-HB-IPV-Hib vaccine administered concomitantly with meningococcal serogroup C conjugate vaccines during the primary infant series.
Rebooting the immune system with high-dose cyclophosphamide for treatment of refractory myasthenia gravis.
Reproducible production of protective human monoclonal antibodies by fusion of peripheral blood lymphocytes with a mouse myeloma cell line.
Safety and immunogenicity of a nonavalent pneumococcal vaccine conjugated to CRM197 administered simultaneously but in a separate syringe with diphtheria, tetanus and pertussis vaccines in Gambian infants.
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers.
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants.
Selective activation of antigen-specific human B cells in recently immunized individuals by nonspecific factors in the absence of antigen.
Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis.
Serum antibodies to the components of diphtheria-tetanus-pertussis vaccine in Polish children related to vaccination status.
Simultaneous multicolor detection system of the single-molecular microbial antigen with total internal reflection fluorescence microscopy.
Surface plasmon resonance analysis of antipolysaccharide antibody specificity: responses to meningococcal group C conjugate vaccines and bacteria.
Synthesis and characterization of lipooligosaccharide-based conjugate vaccines for serotype B Moraxella catarrhalis.
Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys.
Testing for neutralising potential of serum antibodies to tetanus and diphtheria toxin.
Tetanus toxin induces fusion and aggregation of lipid vesicles containing phosphatidylinositol at low pH.
Tetracel (American Home Products).
The adjuvant effect of synthetic oligodeoxynucleotide containing CpG motif converts the anti-Haemophilus influenzae type b glycoconjugates into efficient anti-polysaccharide and anti-carrier polyvalent vaccines.
The effect of caloric supplementation on selected milk protective factors in undernourished Guatemalan mothers.
THE IMMUNIZING POWER OF NUCLEOHISTON AND OF HISTON.
The influence of conjugation variables on the design and immunogenicity of a glycoconjugate vaccine against Salmonella Typhi.
The Pneumococcal Polysaccharide-Tetanus Toxin Native C-Fragment Conjugate Vaccine: The Carrier Effect and Immunogenicity.
The recombinant protein combined vaccine based on the fragment C of tetanus toxin and the cross-reacting material 197.
The short-term impact of each primary dose of pneumococcal conjugate vaccine on nasopharyngeal carriage: Systematic review and meta-analyses of randomised controlled trials.
TOXIN-ANTITOXIN REACTION WITHOUT NEUTRALIZATION.
Vaccination against Group B streptococcus.
Variable region expression in the antibody responses of infants vaccinated with Haemophilus influenzae type b polysaccharide-protein conjugates. Description of a new lambda light chain-associated idiotype and the relation between idiotype expression, avidity, and vaccine formulation. The Collaborative Vaccine Study Group.
[Antibodies against vaccine-preventable diseases in pregnant women and their offspring. Diphtheria, pertussis, tetanus]
[ATTEMPT AT DEMONSTRATION OF DISULFIDE BONDS IN TETANUS TOXIN AND DIPHTHERIA TOXIN.]
[Control of Haemophilus influenzae infections]
[Effects of diphtheria and tetanus toxins on liver regeneration in the rat]
[On the detoxification function of iron uptake: animal experiment studies on the detoxification of botulism A, tetanus and diphtheria toxin by hemosiderin and reducing substances. I.]
Thromboangiitis Obliterans
Study of anti-neutrophil cytoplasmic antibodies in patients with thromboangiitis obliterans (Buerger's disease).
Thrombocytopenia
Genetic platelet depletion is superior in platelet transfusion compared to current models.
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
Thromboinflammation
Extracellular DNA-A Danger Signal Triggering Immunothrombosis.
Thrombophilia
Dietary and Protective Factors to Halt or Mitigate Progression of Autoimmunity, COVID-19 and Its Associated Metabolic Diseases.
Safety and efficacy of lactoferrin versus ferrous sulphate in curing iron deficiency and iron deficiency anaemia in hereditary thrombophilia pregnant women: an interventional study.
Thrombosis
Anti-?2GPI/?2GPI induces neutrophil extracellular traps formation to promote thrombogenesis via the TLR4/MyD88/MAPKs axis activation.
Culprit site extracellular DNA and microvascular obstruction in ST-elevation myocardial infarction.
Detection of extracellular genomic DNA scaffold in human thrombus: implications for the use of deoxyribonuclease enzymes in thrombolysis.
DNAse-dependent, NET-independent pathway of thrombus formation in vivo.
DNase1L3 suppresses hepatocellular carcinoma growth via inhibiting complement autocrine effect.
Extracellular DNA: A Bridge to Cancer.
Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice.
miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis.
Neutrophil extracellular traps promote fibrous vascular occlusions in chronic thrombosis.
Neutrophils and neutrophil extracellular traps enhance venous thrombosis in mice bearing human pancreatic tumors.
Recombinant human DNase I for the treatment of cancer-associated thrombosis: A pre-clinical study.
Thrombotic Microangiopathies
Comparison of the secretory murine DNase1 family members expressed in Pichia pastoris.
Thymoma
Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements.
Detection of DNA replicase activity in rat thymoma cells.
Thymus Hyperplasia
Two polymorphic mutations in promoter region of DNA polymerase ? in relatively higher percentage of thymic hyperplasia patients.
Thyroid Carcinoma, Anaplastic
Anaplastic thyroid carcinoma and foscarnet use in a multitarget treatment documented by 18F-FDG PET/CT: A case report.
Thyroid Diseases
A novel mutation in the DNASE1 gene is related with protein instability and decreased enzyme activity in thyroid autoimmunity.
Immunohistochemical study of ceruloplasmin, lactoferrin and secretory component expression in neoplastic and non-neoplastic thyroid gland diseases.
Reduced DNASE1 Gene Expression in Thyroid Autoimmunity.
Thyroid Neoplasms
Immunohistochemical demonstration of ceruloplasmin in follicular adenomas and thyroid carcinomas.
Immunohistochemical demonstration of lactoferrin in follicular adenomas and thyroid carcinomas.
Immunohistochemical localization of metal binding proteins in thyroid tissues and tumors.
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
Thyroiditis
Experimental autoimmune thyroiditis in the guinea pig: characterization of infiltrating lymphocyte populations.
Reduced DNASE1 Gene Expression in Thyroid Autoimmunity.
Thyroiditis, Autoimmune
[The concentrations of certain cytokins and lactoferrin in blood and supernatants of cell cultures in patients with autoimmune thyroiditis].
Tic Disorders
Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and tics.
Tick-Borne Diseases
Assessment of antibodies against surface and outer membrane proteins of Anaplasma phagocytophilum in Lyme borreliosis and tick-borne encephalitis paediatric patients.
Tinea
Effect of lactoferrin feeding on the host antifungal response in guinea-pigs infected or immunised with Trichophyton mentagrophytes.
Lactoferrin given in food facilitates dermatophytosis cure in guinea pig models.
Tinea Pedis
Oral administration of bovine lactoferrin for treatment of tinea pedis. A placebo-controlled, double-blind study.
Tonsillitis
Lactoferrin gene polymorphisms in Italian patients with recurrent tonsillitis.
Noticeable differences in bacterial defence on tonsillar surfaces between bacteria-induced and virus-induced acute tonsillitis.
[Desoxyribonuclease activity of the saliva and serum in acute respiratory diseases and in acute tonsillitis]
Tooth Injuries
Effects of Vitamin C Intake upon the Degree of Tooth Injury Produced by Diphtheria Toxin.
Toxemia
Studies on the mode of action of diphtheria toxin. V. Protein metabolism in a guinea pig model simulating chronic diphtheritic toxemia.
Toxoplasmosis
Miliary toxoplasmic retinitis in acquired immunodeficiency syndrome.
Prophylactic effect of bovine lactoferrin against acute toxoplasmosis in immunocompetent and immunosuppressed mice.
Tracheitis
Pancreatic deoxyribonuclease (dornase) aerosol in treatment of bronchopulmonary complications and tracheitis sicca.
Trachoma
Reducing suspicion of sexual abuse in paediatric chlamydial conjunctivitis using ompA genotyping.
Tear function in relation to the World Health Organization classification of cicatrization in trachoma.
Transfusion-Related Acute Lung Injury
Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice.
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse.
Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury.
Trichiasis
Lactoferrin Glu561Asp facilitates secondary amyloidosis in the cornea.
[A case of corneal lactoferrin amyloidosis secondary to trichiasis]
Trichomonas Infections
Antitrichomonal activity of metronidazole-loaded lactoferrin nanoparticles in pigeon trichomoniasis.
Iron regulates growth of Trichomonas vaginalis and the expression of immunogenic trichomonad proteins.
Trichomoniasis and lactoferrin: future prospects.
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.
Trigeminal Nerve Injuries
Bovine lactoferrin reduces extra-territorial facial allodynia/hyperalgesia following a trigeminal nerve injury in the rat.
Triple Negative Breast Neoplasms
Anti-tumor Effect of Intravenous Administration of CRM197 for Triple-negative Breast Cancer Therapy.
Immunoexpression of lactoferrin in triple-negative breast cancer patients: A proposal to select a less aggressive subgroup.
Multimodal iron oxide (Fe3O4)-saturated lactoferrin nanocapsules as nanotheranostics for real-time imaging and breast cancer therapy of claudin-low, triple-negative (ER(-)/PR(-)/HER2(-)).
Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells.
Role of Lactoferrin in the Carcinogenesis of Triple-Negative Breast Cancer.
Tuberculosis
A novel recombinant human lactoferrin augments the BCG vaccine and protects alveolar integrity upon infection with Mycobacterium tuberculosis in mice.
A Study on Diagnostic Evaluation of Two Different Rapid DNA Polymerase Chain Reaction Techniques Namely Gene Xpert Mycobacterium Tuberculosis/Rifampin (MTB/RIF) and Mycoreal Polymerase Chain Reaction in the Diagnosis of Endometrial Tuberculosis Considering Culture as Gold Standard.
Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins.
Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis.
Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae.
Characterization of Rv0888, a Novel Extracellular Nuclease from Mycobacterium tuberculosis.
Clinical experience with streptokinase and streptodornase in tuberculosis.
Clinicopathologic characteristics of rosai-dorfman disease in a medical center in northern taiwan.
Cloning and sequence analysis of the gene encoding the DNA polymerase I from Mycobacterium tuberculosis.
Comparing efficacy of BCG/lactoferrin primary vaccination versus booster regimen.
Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis.
Cross-reactivity and sequence homology between the 65-kilodalton mycobacterial heat shock protein and human lactoferrin, transferrin, and DR beta subsets of major histocompatibility complex class II molecules.
Diagnostic value of lactoferrin analysis in pleural effusions.
Effects of CHO-expressed recombinant lactoferrins on mouse dendritic cell presentation and function.
Enzymatic débridement; particular reference to trypsin and desoxyribonuclease in the control of cough and sputum associated with tuberculosis.
Erythema induratum of Bazin as a tuberculid: confirmation of Mycobacterium tuberculosis DNA polymerase chain reaction analysis.
Essential roles for imuA'- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis.
Fluorescence correlation analysis of probe diffusion simplifies quantitative pathogen detection by PCR.
Formation and Disordered Degradation of Neutrophil Extracellular Traps in Necrotizing Lesions of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis.
Functional studies of the Mycobacterium tuberculosis iron-dependent regulator.
Immune Activity of BCG Infected Mouse Macrophages Treated with a Novel Recombinant Mouse Lactoferrin.
Influence of oral lactoferrin on Mycobacterium tuberculosis induced immunopathology.
Iron, mycobacteria and tuberculosis.
Lactoferrin augments BCG vaccine efficacy to generate T helper response and subsequent protection against challenge with virulent Mycobacterium tuberculosis.
Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
Lactoferrin modulation of BCG-infected dendritic cell functions.
Lactoferrin: A Modulator for Immunity against Tuberculosis Related Granulomatous Pathology.
Mechanistic insights into the enzymatic activity and inhibition of the replicative polymerase exonuclease domain from Mycobacterium tuberculosis.
Molecular docking and dynamics simulations studies of OmpATb identifies four potential novel natural product-derived anti-Mycobacterium tuberculosis compounds.
Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity.
Mycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin.
Mycobacterium tuberculosis RecA intein possesses a novel ATP-dependent site-specific double-stranded DNA endonuclease activity.
Oral recombinant human or mouse lactoferrin reduces Mycobacterium tuberculosis TDM induced granulomatous lung pathology.
Purification and properties of DNA polymerase from Mycobacterium tuberculosis H37Rv.
Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity.
Recombinant human lactoferrin modulates human PBMC derived macrophage responses to BCG and LPS.
Synthesis and immunogenicity of PG-tb1 monovalent glycoconjugate.
The association between tuberculosis and diphtheria.
The expression of ferritin, lactoferrin, transferrin receptor and solute carrier family 11A1 in the host response to BCG-vaccination and Mycobacterium tuberculosis challenge.
The RecA intein of Mycobacterium tuberculosis promotes cleavage of ectopic DNA sites. Implications for the dispersal of inteins in natural populations.
The role of DNA polymerase chain reaction, culture and histopathology in the diagnosis of cutaneous tuberculosis.
[Applications of the polymerase chain reaction (PCR) to the diagnosis of central nervous system infections]
[Construction of mycobacterium tuberculosis genomic library]
[Inventive activity of the Department of Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine].
[Iron metabolism and indicators reflecting its changes in pulmonary tuberculosis (literature review).]
[Membrane protein characterization by photoactivatable localization microscopy].
[Streptokinase and streptodornase in tuberculosis.]
[Tubercle bacilli and the defence factors for infection in sputum and bronchoalveolar lavage fluid]
[Use of deoxyribonuclease in the treatment of experimental tuberculosis]
Tuberculosis, Bovine
The skin inflammatory response of the badger (Meles meles).
Tuberculosis, Cutaneous
Erythema induratum of Bazin as a tuberculid: confirmation of Mycobacterium tuberculosis DNA polymerase chain reaction analysis.
Tuberculosis, Meningeal
Tuberculous meningitis presenting with nonconvulsive status epilepticus.
Tuberculosis, Pleural
Intrapleural alteplase and DNase for complex tuberculous pleurisy: a medical approach.
Tuberculosis, Pulmonary
Enzyme linked immunosorbent assay for lactoferrin. Plasma and tissue measurements.
Iron-containing proteins lactoferrin and ferritin in biological media of patients with pulmonary tuberculosis.
Streptokinase and streptodornase in thoracic surgery for pulmonary tuberculosis.
The non-immune inflammatory response: serial changes in plasma iron, iron-binding capacity, lactoferrin, ferritin and C-reactive protein.
[Streptokinase and streptodornase in pulmonary tuberculosis.]
Tuberous Sclerosis
Pentapeptide sharing between Corynebacterium diphtheria toxin and the human neural protein network.
Tularemia
Identification of Francisella tularensis outer membrane protein A (FopA) as a protective antigen for tularemia.
Typhoid Fever
Detection of Rickettsia africae in patients and ticks along the coastal region of Cameroon.
The deoxyribonuclease of typhoid bacilli and its effect on typhoid bacteriophage nucleic acid.
[Determination of colicin sensitivity as a supplementary method of typing typhoid cultures]
[The deoxyribonuclease of typhoid bacteria]
Uremia
[Markers of viral replication (HBeAg and DNA polymerase activity) in chronic uremia, HBsAg positive, hemodialysis patients]
[Surface antigen (HBsAg) and core antibody (anti-HBc) in chronic uremia during periodic hemodialysis treatment of hepatitis B patients. Correlation with viral replication markers (HBeAg and DNA polymerase activity)]
Urethritis
Experimental Gonococcal Infection in Male Volunteers: Cumulative Experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC.
Molecular analysis of two novel Neisseria gonorrhoeae virulent components: the macrophage infectivity potentiator and the outer membrane protein A.
[Lactoferrin assay in urethritis and urethral prostatitis]
Urinary Bladder Neck Obstruction
Inhibition of pressure induced bladder smooth muscle cell hyperplasia using CRM197.
Urinary Bladder Neoplasms
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P3 and IGF2-P4 regulatory sequences.
Thymidine uptake, incorporation and DNA polymerase activity in murine bladder tumor cell, MBT-2, exposed to UV activated dihematoporphyrin ether.
Urinary Tract Infections
A Multi-Technique Reconfigurable Electrochemical Biosensor: Enabling Personal Health Monitoring in Mobile Devices.
Colicin V production by clinical isolates of Escherichia coli.
Dose Escalation Study of Bovine Lactoferrin in Preterm Infants: Getting the Dose Right.
Effect of Varidase (streptodornase) on biofilm formed by Pseudomonas aeruginosa.
Electrochemical immunosensor detection of urinary lactoferrin in clinical samples for urinary tract infection diagnosis.
Enteral Lactoferrin Supplementation for Preventing Sepsis and Necrotizing Enterocolitis in Preterm Infants: A Meta?Analysis With Trial Sequential Analysis of Randomized Controlled Trials.
Fimbria-like hemagglutinin of Escherichia coli O75 strains.
Human lactoferrin and peptides derived from a surface-exposed helical region reduce experimental Escherichia coli urinary tract infection in mice.
Measurement of urinary lactoferrin as a marker of urinary tract infection.
Serum resistance among Escherichia coli strains causing urinary tract infection in relation to O type and the carriage of hemolysin, colicin, and antibiotic resistance determinants.
The association between colicinogenicity and pathogenesis among uropathogenic isolates of Escherichia coli.
Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence.
Virulence factors of Escherichia coli in urinary isolates.
Virulence factors of uropathogenic Escherichia coli from a university hospital in Ribeirão Preto, São Paulo, Brazil.
[Frequency of colicin and hemolysins in Escherichia coli isolated from pregnant patients with urinary tract infection, symptomatic and asymptomatic]
Uterine Cervical Neoplasms
Bovine lactoferrin and lactoferrin peptides affect endometrial and cervical cancer cell lines.
Combination therapy with podophyllin and vidarabine for human papillomavirus positive cervical intraepithelial neoplasia.
Comparisons of HPV DNA detection by MY09/11 PCR methods.
DNA polymerase ? as a potential biomarker of chemoradiation resistance and poor prognosis for cervical cancer.
Expression of the h19 oncofetal gene in premalignant lesions of cervical cancer: a potential targeting approach for development of nonsurgical treatment of high-risk lesions.
Growth suppression effects of recombinant adenovirus expressing human lactoferrin on cervical cancer in vitro and in vivo.
Lactoferrin-induced up-regulation of zeta (zeta) chain expression in peripheral blood T lymphocytes from cervical cancer patients.
Prognostic significance of human papillomavirus detected with polymerase chain reaction in cervical cancer.
Use of the Rad51 promoter for targeted anti-cancer therapy.
[HISTOCHEMICAL STUDY ON THE ACTIVITY OF ACID DESOXYRIBONUCLEASE IN CANCER OF THE UTERINE CERVIX.]
Uterine Cervicitis
Cervical inflammatory cytokines and other markers in the cervical mucus of pregnant women with lower genital tract infection.
Lactoferrin in cervical mucus as a biochemical marker for inflammation.
Streptokinase and streptodornase (varidase) in the treatment of cervicitis; a clinical evaluation.
Uveitis
Clinical Effects of Bovine Lactoferrin on Two Canine Cases with Familial Neutrophil Dysfunction.
Molecular mimicry between a uveitopathogenic site of S-antigen and viral peptides. Induction of experimental autoimmune uveitis in Lewis rats.
[The superoxide theory of pathogenesis and therapy of immune disorders]
Vaccinia
A biological method for examining the effect of codon changes in a conserved region of DNA polymerase.
A small molecule screen in yeast identifies inhibitors targeting protein-protein interactions within the vaccinia virus replication complex.
Analysis of SEC-SAXS data via EFA deconvolution and Scatter.
Analysis of the adenovirus type 5 terminal protein precursor and DNA polymerase by linker insertion mutagenesis.
Association of mitochondria DNA with viral DNA in purified preparations of poxviruses.
Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase.
Cellular DNA ligase I is recruited to cytoplasmic vaccinia virus factories and masks the role of the vaccinia ligase in viral DNA replication.
Characterization of a processive form of the vaccinia virus DNA polymerase.
Characterization of an R-binding site mediating the R-induced activation of the Epstein-Barr virus BMLF1 promoter.
Characterization of Deoxyribonucleases Induced by Poxviruses.
Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand.
Cloning and structural-functional studies for 7.5k promoter of Tiantan strain of vaccinia virus.
Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.
Comparative whole genome sequence analysis of wild-type and cidofovir-resistant monkeypoxvirus.
Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit d4 in complex with the a20 N-terminal domain.
Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA.
DNA polymerase and deoxyribonucleotide kinase activities in cells infected with vaccinia virus.
DNA strand exchange catalyzed by proteins from vaccinia virus-infected cells.
Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase.
Effects of DNA structure and homology length on vaccinia virus recombination.
Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase.
Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme.
Expression analysis of recombinant herpes simplex virus type 1 DNase.
Expression and characterization of bovine lactoperoxidase by recombinant vaccinia virus.
Expression of herpes simplex virus type 1 DNA polymerase by recombinant vaccinia virus.
Extrachromosomal recombination in vaccinia-infected cells requires a functional DNA polymerase participating at a level other than DNA replication.
Failure of poxvirus replication in the presence of an inhibitor of nucleolar RNA synthesis.
Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.
Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.
Genetic evidence for vaccinia virus-encoded DNA polymerase: isolation of phosphonoacetate-resistant enzyme from the cytoplasm of cells infected with mutant virus.
High expression of functional adenovirus DNA polymerase and precursor terminal protein using recombinant vaccinia virus.
Homology between DNA polymerases of poxviruses, herpesviruses, and adenoviruses: nucleotide sequence of the vaccinia virus DNA polymerase gene.
Identification and sequencing of the Choristoneura biennis entomopoxvirus DNA polymerase gene.
Identification by a random sequencing strategy of the fowlpoxvirus DNA polymerase gene, its nucleotide sequence and comparison with other viral DNA polymerases.
Identification of Inhibitors that Block Vaccinia Virus Infection by Targeting the DNA Synthesis Processivity Factor D4.
Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach.
In vitro concatemer formation catalyzed by vaccinia virus DNA polymerase.
In-fusion® cloning with vaccinia virus DNA polymerase.
Increased turnover of vaccinia virus-specific immediate early RNAs in interferon-treated chick embryo fibroblasts.
Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir.
Inhibition of vaccinia virus growth by the nucleoside analogue 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ribavirin).
Isolation and characterization of cidofovir resistant vaccinia viruses.
Location, DNA sequence and transcriptional analysis of the DNA polymerase gene of orf virus.
Looking back at smallpox.
Mapping interaction sites of the A20R protein component of the vaccinia virus DNA replication complex.
Mapping of the vaccinia virus DNA polymerase gene by marker rescue and cell-free translation of selected RNA.
Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs.
Mechanism of inhibition of adenovirus DNA replication by the acyclic nucleoside triphosphate analogue (S)-HPMPApp: influence of the adenovirus DNA binding protein.
Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate.
Molecular genetic analysis of vaccinia virus DNA polymerase mutants.
Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus give different drug-susceptibility profiles in vaccinia virus.
Mutations in two cysteine-histidine-rich clusters in adenovirus type 2 DNA polymerase affect DNA binding.
Nucleotide sequence of the DNA polymerase gene of herpes simplex virus type 2 and comparison with the type 1 counterpart.
Origin-independent plasmid replication occurs in vaccinia virus cytoplasmic factories and requires all five known poxvirus replication factors.
Orthopoxvirus DNA: a comparison of restriction profiles and maps.
Overexpression and purification of the vaccinia virus DNA polymerase.
Production and characterization of antibodies against vaccinia virus DNA polymerase.
Purification and properties of the deoxyribonucleic acid polymerase induced by vaccinia virus.
Selection for temperature-sensitive mutations in specific vaccinia virus genes: isolation and characterization of a virus mutant which encodes a phosphonoacetic acid-resistant, temperature-sensitive DNA polymerase.
Site of the base change in the vaccinia virus DNA polymerase gene which confers aphidicolin resistance.
Site-specific interaction of vaccinia virus topoisomerase I with duplex DNA. Minimal DNA substrate for strand cleavage in vitro.
Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir.
Solution Structure of the C-terminal Domain of A20, the Missing Brick for the Characterization of the Interface between Vaccinia Virus DNA Polymerase and its Processivity Factor.
Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.
Structural analysis of ternary complexes of vaccinia RNA polymerase.
Synthesis of herpes simplex virus, vaccinia virus, and adenovirus DNA in isolated HeLa cell nuclei. I. Effect of viral-specific antisera and phosphonoacetic acid.
Targeting of Sp1 to a non-Sp1 site in the human neurofilament (H) promoter via an intermediary DNA-binding protein.
The 3'-to-5' exonuclease activity of vaccinia virus DNA polymerase is essential and plays a role in promoting virus genetic recombination.
The A20R protein is a stoichiometric component of the processive form of vaccinia virus DNA polymerase.
The DNA polymerase activity of vaccinia virus 'virosomes': solubilization and properties.
The effect of deoxyribonuclease on the synthesis of DNA of vaccinia virus.
The effect of template secondary structure on vaccinia DNA polymerase.
The vaccinia virus DNA polymerase and its processivity factor.
The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Transcriptional mapping of the DNA polymerase gene of vaccinia virus.
Transcriptional mapping of the vaccinia virus DNA polymerase gene.
Transient expression of the vaccinia virus DNA polymerase is an intrinsic feature of the early phase of infection and is unlinked to DNA replication and late gene expression.
Two deoxyribonuclease activities within purified vaccinia virus.
Vaccinia virus d4 mutants defective in processive DNA synthesis retain binding to a20 and DNA.
Vaccinia virus DNA polymerase promotes DNA pairing and strand-transfer reactions.
Vaccinia virus DNA polymerase. In vitro analysis of parameters affecting processivity.
Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase.
[Effect of inhibitors of vaccinia virus reproduction on deoxyribonuclease induction in tissue culture]
[Synthesis of DNA polymerase at a supra-optimal temperature in the cytoplasm of KB cells infected with a "cold" mutant of the vaccinia virus]
[The effect of deoxyribonuclease on the incorporation of thymidine-H3 into cells infected by vaccinia virus]
Vaginal Discharge
Streptokinase and streptodornase in the treatment of postoperative vaginal discharge.
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.
[An association of selected polymorphisms of the lactoferrin gene and genes for lactoferrin receptors in the prevalence of metabolic disorders in obese subjects].
Vaginitis
Administration of oral and vaginal prebiotic lactoferrin for a woman with a refractory vaginitis recurring preterm delivery: appearance of lactobacillus in vaginal flora followed by term delivery.
Vaginosis, Bacterial
Bacterial biota of women with bacterial vaginosis treated with lactoferrin: an open prospective randomized trial.
Cervical inflammatory cytokines and other markers in the cervical mucus of pregnant women with lower genital tract infection.
Effects of lactoferrin in 6 patients with refractory bacterial vaginosis.
Evidence-based mixture containing Lactobacillus strains and lactoferrin to prevent recurrent bacterial vaginosis: a double blind, placebo controlled, randomised clinical trial.
The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.
Vaginal lactoferrin in prevention of preterm birth in women with bacterial vaginosis.
Varicocele
Alterations in the proliferative/apoptotic equilibrium in semen of adolescents with varicocele.
Deoxyribonucleic acid polymerase activity in the testes of infertile men with varicocele.
Varicose Veins
Plasma matrix metalloproteinase-9 as a marker of blood stasis in varicose veins.
Vascular Diseases
Chronic Stimulation of Renin Cells Leads to Vascular Pathology.
Vascular System Injuries
A PHYSIOLOGICAL STUDY OF EXPERIMENTAL NEPHRITIS DUE TO BACTERIAL POISONS AND CYTOTOXIC SERA.
Vasculitis
Antigen specificity in hydralazine associated ANCA positive systemic vasculitis.
Cutaneous vasculitis in breast cancer treated with chemotherapy.
DNASE1L3 mutations in hypocomplementemic urticarial vasculitis syndrome.
Molecular characteristics of anti-self antibody fragments against neutrophil cytoplasmic antigens from human V gene phage display libraries.
Neutrophil Extracellular Traps (NETs) and Vasculitis.
Phantom cytomegalovirus infection in vasculitis patients: what it means and what to do.
Tubulointerstitial nephritis and vasculitis.
Varicella-zoster vasculitis presenting with cerebellar hemorrhage.
Venous Thrombosis
Update from the laboratory: mechanistic studies of pathways of cancer-associated venous thrombosis using mouse models.
Ventricular Dysfunction, Left
Acute DNase1 treatment improves left ventricular remodeling after myocardial infarction by disruption of free chromatin.
Vesico-Ureteral Reflux
Unilateral vesicoureteral reflux in children. study on urine specific gravity, osmolality, beta-2-microglobulin and lactoferrin.
Vesicular Stomatitis
A single mutation in Chinese hamster ovary cells impairs both Golgi and endosomal functions.
Viremia
Comparative study of DHBV DNA levels and endogenous DNA polymerase activity in naturally infected ducklings in France.
Cytomegalovirus viremia, mortality, and end-organ disease among patients with AIDS receiving potent antiretroviral therapies.
Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin.
Hepatitis B virus carrier with low titer of antibody to hepatitis B core antigen.
Kinetics of appearance of neutralizing antibodies in 12 patients with primary or recent HIV-1 infection and relationship with plasma and cellular viral loads.
Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b.
Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study.
Virus Diseases
Activities of arabinosyladenine monophosphate and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against ground squirrel hepatitis virus in vivo as determined by reduction in serum virion-associated DNA polymerase.
Acyclovir-resistant herpes simplex virus infection due to altered DNA polymerase.
Adenovirus preterminal protein synthesized in COS cells from cloned DNA is active in DNA replication in vitro.
Antiadenovirus activity of milk proteins: lactoferrin prevents viral infection.
Antiviral activity of human lactoferrin: inhibition of alphavirus interaction with heparan sulfate.
Antiviral effects of nisin, lysozyme, lactoferrin and their mixtures against bovine viral diarrhoea virus.
Antiviral properties of lactoferrin-a natural immunity molecule.
Antiviral Resistance of Splenocytes in Aged Mice.
Bovine Lactoferrin Inhibits Dengue Virus Infectivity by Interacting with Heparan Sulfate, Low-Density Lipoprotein Receptor, and DC-SIGN.
Bovine lactoferrin inhibits Influenza A virus induced programmed cell death in vitro.
Bovine lactoferrin inhibits toscana virus infection by binding to heparan sulphate.
Bovine Lactoferrin Prevents Influenza A Virus Infection by Interfering with the Fusogenic Function of Viral Hemagglutinin.
Bovine lactoferrin: involvement of metal saturation and carbohydrates in the inhibition of influenza virus infection (1) (1) This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process.
Characterization of antiviral activity of lactoferrin against hepatitis C virus infection in human cultured cells.
Characterization of the anti-HBV activity of HLP1-23 , a human lactoferrin-derived peptide.
Characterization of the Epstein-Barr virion-associated DNA polymerase as isolated from superinfected and drug-stimulated cells.
Crystal structure of the herpes simplex virus 1 DNA polymerase.
Cytochemical studies of polyoma virus infection. 3. Deoxyribonuclease II.
Directed evolution of an error-prone T7 DNA polymerase that attenuates viral replication.
DNA polymerase activities induced by polyoma virus infection of 3T3 mouse fibroblasts.
DNA polymerase gene locus of Cercopithecine herpesvirus 1 is a suitable target for specific and rapid identification of viral infection by PCR technology.
Early human milk lactoferrin during SARS-CoV-2 infection.
Effect of bovine lactoferrin on functions of activated feline peripheral blood mononuclear cells during chronic feline immunodeficiency virus infection.
Effects of adenine arabinoside on serum and intrahepatic replicative forms of duck hepatitis B virus in chronic infection.
Effects of orally administered bovine lactoferrin and lactoperoxidase on influenza virus infection in mice.
Efficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase.
Equine herpesvirus type 1 infection induces procoagulant activity in equine monocytes.
Foscarnet decreases serum and liver duck hepatitis B virus DNA in chronically infected ducks.
Glycosaminoglycans are not indispensable for the anti-herpes simplex virus type 2 activity of lactoferrin.
Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease.
Herpesvirus DNA polymerase processivity factors: Not just for DNA synthesis.
Highlights in the development of new antiviral agents.
Human and viral nucleoside/nucleotide kinases involved in antiviral drug activation: structural and catalytic properties.
Immune gene expression profile of Penaeus monodon in response to marine yeast glucan application and white spot syndrome virus challenge.
Immunity to Haemophilus influenzae type b after reimmunization with oligosaccharide CRM197 conjugate vaccine in children with human immunodeficiency virus infection.
Immunity to Haemophilus influenzae type b polysaccharide capsule after vaccination with the complete series of oligosaccharide CRM197 conjugate vaccine in infants with human immunodeficiency virus infection.
Induction of thymidine kinase and DNase in varicella-zoster virus-infected cells and kinetic properties of the virus-induced thymidine kinase.
Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation.
Inhibition of herpes simplex virus infection by lactoferrin is dependent on interference with the virus binding to glycosaminoglycans.
Inhibition of herpes simplex virus type 1 by small interfering RNA.
Inhibition of poliovirus type 1 infection by iron-, manganese- and zinc-saturated lactoferrin.
Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks.
Inhibitory effects of native and recombinant full-length camel lactoferrin and its N and C lobes on hepatitis C virus infection of Huh7.5 cells.
Involvement of the reparative DNA polymerase pol x of african Swine Fever virus in the maintenance of viral genome stability in vivo.
Isolation of foscarnet-resistant human cytomegalovirus patterns of resistance and sensitivity to other antiviral drugs.
Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection.
Lactoferrin and the inflammatory response.
Lactoferrin as Protective Natural Barrier of Respiratory and Intestinal Mucosa against Coronavirus Infection and Inflammation.
Lactoferrin for prevention of common viral infections.
Lactoferrin in relation to acute phase proteins in sera from newborn infants with severe infections.
Lactoferrin inhibits early steps of human BK polyomavirus infection.
Lactoferrin markedly inhibits hepatitis C virus infection in cultured human hepatocytes.
Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors.
Marine actinomycetes as bioremediators in Penaeus monodon rearing system.
Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection.
Natural resources to control COVID-19: could lactoferrin amend SARS-CoV-2 infectivity?
Neutrophil lactoferrin content in viral infections.
Occurrence of Epstein-Barr virus deoxyribonuclease enzyme activity-neutralizing antibodies. An index of Epstein-Barr virus disease.
Ovotransferrin expression and release by chicken cell lines infected with Marek's disease virus.
Penile cutaneous horn ten years after treatment of verrucous squamous cell carcinoma on penile glans: case report.
Plasma lactoferrin content: differential effect of steroid administration and infective illnesses: lack of effect of ambient temperature at which specimens are collected.
Protection of transgenic tobacco plants expressing bovine pancreatic ribonuclease against tobacco mosaic virus.
Regulation of the Epstein-Barr virus DNA polymerase gene.
Systematic review of the biology and medical management of respiratory syncytial virus infection.
The effect of bovine lactoferrin and lactoferricin B on the ability of feline calicivirus (a norovirus surrogate) and poliovirus to infect cell cultures.
The effects of orally administered lactoferrin in the prevention and management of viral infections: A systematic review.
The Immunological Role of the Placenta in SARS-CoV-2 Infection-Viral Transmission, Immune Regulation, and Lactoferrin Activity.
The role of ATF in regulating the human cytomegalovirus DNA polymerase (UL54) promoter during viral infection.
Unusual regulation of expression of the herpes simplex virus DNA polymerase gene.
[The effect of nucleotides on oligomeric state of human lactoferrin]
[The enhancement of cell resistance against diphtheria toxin under the influence of latent viral infection]
[Transgenic Expression of Serratia marcescens Native and Mutant Nucleases Modulates Tobacco Mosaic Virus Resistance in Nicotiana tabacum L].
Visna
DNA polymerase activities in varions of visna virus, a causative agent of a "slow" neurological disease.
Multiple activities of DNA polymerase from visna virus.
Proceedings: Characterization of DNA polymerase from visna virus.
Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites.
[The RNA dependant DNA polymerase of Visna virus. Study of the products of the reaction]
Vitamin A Deficiency
[Effect of increased doses of cobalt on ribonuclease, desoxyribonuclease and catalase in vitamin A deficiency]
Vitamin B 6 Deficiency
[Activity of testicular acid DNAase in guinea pigs with pyridoxine deficiency]
Vitreoretinopathy, Proliferative
Iron-binding proteins in the human vitreous: lactoferrin and transferrin in health and in proliferative intraocular disorders.
Warts
Immunolocalization of lactoferrin in surgically resected pigmented skin lesions.
Werner Syndrome
DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA.
Enhancement of human DNA polymerase ? activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein.
Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage.
Mutations induced by 8-oxo-7,8-dihydroguanine in WRN- and DNA polymerase ?-double knockdown cells.
The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase ?
Whooping Cough
A Belgian Serosurveillance/Seroprevalence Study of Diphtheria, Tetanus and Pertussis Using a Luminex xMAP Technology-Based Pentaplex.
Antibody responses of healthy infants to concurrent administration of a bivalent haemophilus influenzae type b-hepatitis B vaccine with diphtheria-tetanus-pertussis, polio and measles-mumps-rubella vaccines.
Antibody responses to Bordetella pertussis and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy- a prospective, observational cohort study from the UK.
Bordetella pertussis fim3 gene regulation by BvgA: Phosphorylation controls the formation of inactive vs. active transcription complexes.
Botulinum C2 toxin ADP-ribosylates actin.
Cloning, nucleotide sequence, and hybridization studies of the type IIb heat-labile enterotoxin gene of Escherichia coli.
Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins.
Comparison of a fifth dose of a five-component acellular or a whole cell pertussis vaccine in children four to six years of age.
Computer modelling of the NAD binding site of ADP-ribosylating toxins: active-site structure and mechanism of NAD binding.
Concomitant administration of diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) with pentavalent rotavirus vaccine in Japanese infants.
Conservation of a common motif in enzymes catalyzing ADP-ribose transfer. Identification of domains in mammalian transferases.
Construction of a diphtheria toxin A fragment-C180 peptide fusion protein which elicits a neutralizing antibody response against diphtheria toxin and pertussis toxin.
Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation.
Detection of arginine-ADP-ribosylated protein using recombinant ADP-ribosylarginine hydrolase.
Development and validation of a multiplex immunoassay for the simultaneous determination of serum antibodies to Bordetella pertussis, diphtheria and tetanus.
Diphtheria, tetanus and pertussis antibodies in 10-year-old children before and after a booster dose of three toxoids: implications for the timing of a booster dose.
Effect of tumor necrosis factor and granulocyte/macrophage colony-stimulating factor on neutrophil degranulation.
Effect on meningococcal serogroup W immunogenicity when Tdap was administered prior, concurrent or subsequent to the quadrivalent (ACWY) meningococcal CRM197-conjugate vaccine in adult Hajj pilgrims: A randomised controlled trial.
Expression and purification of a trivalent pertussis toxin-diphtheria toxin-tetanus toxin fusion protein in Escherichia coli.
Extensive swelling after booster doses of acellular pertussis-tetanus-diphtheria vaccines.
Fast, antigen-saving multiplex immunoassay to determine levels and avidity of mouse serum antibodies to pertussis, diphtheria, and tetanus antigens.
Generation of plant-derived recombinant DTP subunit vaccine.
Genome-Wide Association Mapping of the Antibody Response to Diphtheria, Tetanus and Acellular Pertussis Vaccine in Mice.
Identification and purification of transferrin- and lactoferrin-binding proteins of Bordetella pertussis and Bordetella bronchiseptica.
Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.
Infant antibody levels following 10-valent pneumococcal-protein D conjugate and DTaP-Hib vaccinations in the first year of life after maternal Tdap vaccination: An open-label, parallel, randomised controlled trial.
Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium.
Inhibition of murine allergic airway disease by Bordetella pertussis.
Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states.
Interaction of lactoferrin and transferrins with the outer membrane of Bordetella pertussis.
Interspecies variations in Bordetella catecholamine receptor gene regulation and function.
Lymphotoxin induces secretion of granule proteins from adherent neutrophils: possible role of intracellular free calcium.
mADP-RTs: versatile virulence factors from bacterial pathogens of plants and mammals.
Measuring immunoglobulin g antibodies to tetanus toxin, diphtheria toxin, and pertussis toxin with single-antigen enzyme-linked immunosorbent assays and a bead-based multiplex assay.
Novel bacterial ADP-ribosylating toxins: structure and function.
Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach.
Oral immunogenicity of tomato-derived sDPT polypeptide containing Corynebacterium diphtheriae, Bordetella pertussis and Clostridium tetani exotoxin epitopes.
Pertussis prevalence and its determinants among children with persistent cough in urban Uganda.
Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells.
Phosphorylation, desensitization and internalization of human alpha1B-adrenoceptors induced by insulin-like growth factor-I.
Protective immunogenicity of synthetic peptides selected from the amino acid sequence of Bordetella pertussis toxin subunit S1.
Protective immunogenicity of two synthetic peptides selected from the amino acid sequence of Bordetella pertussis toxin subunit S1.
Safety and immunogenicity of a nonavalent pneumococcal vaccine conjugated to CRM197 administered simultaneously but in a separate syringe with diphtheria, tetanus and pertussis vaccines in Gambian infants.
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers.
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants.
Sequence and structural links between distant ADP-ribosyltransferase families.
Seroepidemiology of diphtheria and pertussis in Chongqing, China: serology-based evidence of Bordetella pertussis infection.
Seroprevalence and placental transportation of maternal antibodies specific for Neisseria meningitidis serogroup C, Haemophilus influenzae type B, diphtheria, tetanus, and pertussis.
Serum antibodies to the components of diphtheria-tetanus-pertussis vaccine in Polish children related to vaccination status.
Siderophore production and membrane alterations by Bordetella pertussis in response to iron starvation.
Signal transduction mechanisms for leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils.
Subcellular localization of Gi alpha in human neutrophils.
Successful mucolysis in pertussis using bronchoscopically applied dornase alfa.
Tetracel (American Home Products).
The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on antibody responses to routine immunisations given in infancy: Secondary analysis of a randomised controlled trial.
The relationship between low density lipoprotein-related protein/alpha 2-macroglobulin (alpha 2M) receptors and the newly described alpha 2M signaling receptor.
Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin.
Use of biotinylated NAD to label and purify ADP-ribosylated proteins.
Vaccines, emerging viruses, and how to avoid disaster.
[Antibodies against vaccine-preventable diseases in pregnant women and their offspring. Diphtheria, pertussis, tetanus]
[The risk of pertussis and diphtheria infections among pediatric healthcare workers in Japan]
Wilms Tumor
Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.
Wound Infection
Antibiofilm Potential of Silver Sulfadiazine-Loaded Nanoparticle Formulations: A Study on the Effect of DNase-I on Microbial Biofilm and Wound Healing Activity.
Xeroderma Pigmentosum
A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta.
A processive versus a distributive mechanism of action correlates with differences in ability of normal and xeroderma pigmentosum group A endonucleases to incise damaged nucleosomal DNA.
Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
Angiosarcoma Arising from the Tongue of an 11-Year-Old Girl with Xeroderma Pigmentosum.
Defective DNA endonuclease activity on anthramycin treated DNA in xeroderma pigmentosum and mouse melanoma cells.
Deficient DNA binding of an apurinic/apyrimidinic DNA endonuclease activity from xeroderma pigmentosum cells.
Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals.
Distribution of u.v.-induced repair events in higher-order chromatin loops in human and hamster fibroblasts.
DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation.
DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.
Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant.
Enhancement of two apurinic/apyrimidinic endonuclease activities from normal but not xeroderma pigmentosum lymphoblastoid cells by nucleosome structure.
FEN1 participates in repair of the 5'-phosphotyrosyl terminus of DNA single-strand breaks.
GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase ?.
Human xeroderma pigmentosum group G gene encodes a DNA endonuclease.
Isolation of a DNA endonuclease complex in XPD cells which is defective in ability to incise nucleosomal DNA containing pyrimidine dimers.
Nuclear deoxyribonuclease activities in normal and xeroderma pigmentosum lymphoblastoid cells.
Nuclear DNA endonuclease activities on partially apurinic/apyrimidinic DNA in normal human and xeroderma pigmentosum lymphoblastoid and mouse melanoma cells.
Nucleotide excision repair pathways involved in Cisplatin resistance in non-small-cell lung cancer.
Nucleotide Excision Repair, XPA-1, and the Translesion Synthesis Complex, POLZ-1 and REV-1, Are Critical for Interstrand Cross-Link Repair in Caenorhabditis elegans Germ Cells.
Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene.
Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H.
Relative importance of incision and polymerase activities in determining the distribution of damaged sites that are mended in xeroderma pigmentosum group C cells.
Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice.
Replication of damaged DNA: molecular defect in xeroderma pigmentosum variant cells.
Simultaneous disruption of two DNA polymerases, Pol? and Pol?, in Avian DT40 cells unmasks the role of Pol? in cellular response to various DNA lesions.
Stalled Pol? at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1.
Structure and mechanism of human DNA polymerase eta.
The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells.
Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
Two DNA endonuclease activities from normal human and xeroderma pigmentosum chromatin active on psoralen plus ultraviolet light treated DNA.
UV-induced mutations in epidermal cells of mice defective in DNA polymerase ? and/or ?
Xeroderma pigmentosum endonuclease complexes show reduced activity on and affinity for psoralen cross-linked nucleosomal DNA.
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.
Xeroderma pigmentosum variant: Complementary molecular approaches to detect a 13 base pair deletion in the DNA polymerase eta gene.
Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase.
XPG gene polymorphisms and cancer susceptibility: evidence from 47 studies.
[Studies on the activity of deoxyribonuclease in skin from xeroderma pigmentosum patients]
Xerostomia
Clinical applications of antimicrobial host proteins lactoperoxidase, lysozyme and lactoferrin in xerostomia: efficacy and safety.
Effects of oral hygiene products containing lactoperoxidase, lysozyme, and lactoferrin on the composition of whole saliva and on subjective oral symptoms in patients with xerostomia.
Lactoferrin, amylase and mucin MUC5B and their relation to the oral microflora in hyposalivation of different origins.
Minor gland saliva flow rate and proteins in subjects with hyposalivation due to Sjogren's syndrome and radiation therapy.
The effect of two artificial salivas on the adhesion of Candida albicans to heat-polymerized acrylic resin.
Yersinia Infections
Colicin FY inhibits pathogenic Yersinia enterocolitica in mice.