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Information on EC 3.1.2.21 - dodecanoyl-[acyl-carrier-protein] hydrolase

for references in articles please use BRENDA:EC3.1.2.21

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IUBMB Comments

Acts on the acyl-carrier-protein thioester of C12 and, with a much lower activity, C14 fatty acids. The derivative of oleic acid is hydrolysed very slowly (cf. EC 3.1.2.14, oleoyl-[acyl-carrier-protein] hydrolase).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
12-acp thioesterase, 12:0-acp te, lauroyl-acp thioesterase, lauroyl-acyl carrier protein thioesterase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a dodecanoyl-[acyl-carrier protein] + H2O = an [acyl-carrier protein] + dodecanoate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
palmitate biosynthesis I (type I fatty acid synthase), palmitate biosynthesis II (type II fatty acid synthase), tetradecanoate biosynthesis (mitochondria)
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