Reference on EC 3.1.1.79 - hormone-sensitive lipase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tsujita,T.; Okuda, H.
Hydrolysis of cholesteryl oleate liquid crystals by hormon-sensitive lipase
J. Biochem.
113
264-269
1993
Bos taurus
Lee, F.T.; Adams, J.B.; Garton, A.J.; Yeaman, S.J.
Hormone-sensitive lipase is involved in the hydrolysis of lipoidal derivatives of estrogens and other steroid hormones
Biochim. Biophys. Acta
963
258-264
1988
Bos taurus
Tsujita, T.; Ninomiya, H.; Okuda, H.
p-Nitrophenyl butyrate hydrolyzing activity of hormone-sensitive lipase from bovine adipose tissue
J. Lipid Res.
30
997-1004
1989
Bos taurus
Yeaman, S.J.
Hormone-sensitive lipase - new roles for an old enzyme
Biochem. J.
379
11-22
2004
Homo sapiens, Mus musculus, Rattus norvegicus
Yeaman, S.J.; Smith, G.M.; Jepson, C.A.; Wood, S.L.; Emmison, N.
The multifunctional role of hormone-sensitive lipase in lipid metabolism
Adv. Enzyme Regul.
34
355-370
1994
Bos taurus
Langfort, J.; Ploug, T.; Ihlemann, J.; Enevoldsen, L.H.; Stallknecht, B.; Saldo, M.; Kjaer, M.; Holm, C.; Galbo, H.
Hormone-sensitive lipase (HSL) expression and regulation in skeletal muscle
Adv. Exp. Med. Biol.
441
219-228
1998
Rattus norvegicus
Shih, M.F.; Taberner, P.V.
Effects of acute and chronic ethanol administration on the response of mouse adipose tissue hormone-sensitive lipase to alpha(2)-adrenoceptor activation bu UK 14304
Alcohol Alcohol.
36
381-387
2001
Mus musculus
Holm, C.; Belfrage, P.; Fredrikson, G.
Immunological evidence for the presence of hormone-sensitive lipase in rat tissues other than adipose tissue
Biochem. Biophys. Res. Commun.
148
99-105
1987
Rattus norvegicus
Remaury, A.; Laurell, H.; Grober, J.; Reynisdottir, S.; Dauzats, M.; Holm, C.; Langin, D.
Expression of hormone-sensitive lipase in the human colon adenocarcinoma cell line HT29
Biochem. Biophys. Res. Commun.
207
175-182
1995
Homo sapiens
Mairal, A.; Melaine, N.; Laurell, H.; Grober, J.; Holst, L.S.; Guillaudeux, T.; Holm, C.; Jegou, B.; Langin, D.
Characterization of a novel testicular form of human hormone-sensitive lipase
Biochem. Biophys. Res. Commun.
291
286-290
2002
Homo sapiens
Small, C.A.; Garton, A.J.; Yeaman, S.J.
The presence and role of hormone-sensitive lipase in heart muscle
Biochem. J.
258
67-72
1989
Bos taurus
Langfort, J.; Ploug, T.; Ihlemann, J.; Saldo, M.; Holm, C.; Galbo, H.
Expression of hormone-sensitive lipase and its regulation by adrenaline in skeletal muscle
Biochem. J.
340
459-465
1999
Rattus norvegicus
-
Pease, R.J.; Wiggins, D.; Saggerson, E.D.; Tree, J.; Gibbons, G.F.
Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase
Biochem. J.
341
453-460
1999
Rattus norvegicus
-
Shen, W.J.; Patel, S.; Natu, V.; Kraemer, F.B.
Mutational analysis of structural features of rat hormone-sensitive lipase
Biochemistry
37
8973-8979
1998
Rattus norvegicus
Shen, W.J.; Patel, S.; Hong, R.; Kraemer, F.B.
Hormone-sensitive lipase functions as an oligomer
Biochemistry
39
2392-2398
2000
Rattus norvegicus
Ben Ali, Y.; Chahinian, H.; Petry, S.; Muller, G.; Carriere, F.; Verger, R.; Abousalham, A.
Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain?
Biochemistry
43
9298-9306
2004
Homo sapiens
Holm, C.; Belfrage, P.; Fredrikson, G.
Human adipose tissue hormone-sensitive lipase: identification and comparison with other species
Biochim. Biophys. Acta
1006
193-197
1989
Homo sapiens, Rattus norvegicus
Small, C.A.; Yeaman, S.J.; West, D.W.; Clegg, R.A.
Cholesterol ester hydrolysis and hormone-sensitive lipase in lactating rat mammary tissue
Biochim. Biophys. Acta
1082
251-254
1991
Rattus norvegicus
Cordle, S.R.; Colbran, R.J.; Yeaman, S.J.
Hormone-sensitive lipase from bovine adipose tissue
Biochim. Biophys. Acta
887
51-57
1986
Bos taurus
Lee, F.T.; Yeaman, S.J.; Fredrikson, G.; Stralfors, P.; Belfrage, P.
Hormone-sensitive lipase from swine adipose tissue: identification and some properties
Comp. Biochem. Physiol. B
80
609-612
1985
Sus scrofa
Haemmerle, G.; Zimmermann, R.; Zechner, R.
Letting lipids go: hormone-sensitive lipase
Curr. Opin. Lipidol.
14
289-297
2003
Mus musculus
Osterlund, T.
Structure-function relationships of hormone-sensitive lipase
Eur. J. Biochem.
268
1899-1907
2001
Homo sapiens, Mus musculus, Rattus norvegicus
Holm, C.; Davis, R.C.; Fredrikson, G.; Belfrage, P.; Schotz, M.C.
Expression of biologically active hormone-sensitive lipase in mammalian (COS) cells
FEBS Lett.
285
139-144
1991
Rattus norvegicus
Mersmann, H.J.
Lipoprotein and hormone-sensitive lipases in porcine adipose tissue
J. Anim. Sci.
76
1396-1404
1998
Sus scrofa
Fredrikson, G.; Belfrage, P.
Positional specificity of hormone-sensitive lipase from rat adipose tissue
J. Biol. Chem.
258
14253-14256
1983
Rattus norvegicus
Hazel, J.R.; Sidell, B.D.
The substrate specificity of hormone-sensitive lipase from adipose tissue of the Antarctic fish Trematomus newnesi
J. Exp. Biol.
207
897-903
2004
Trematomus newnesi
Raclot, T.; Holm, C.; Langin, D.
Fatty acid specificity of hormone-sensitive lipase: implication in the selective hydrolysis of triacylglycerols
J. Lipid Res.
42
2049-2057
2001
Homo sapiens, Rattus norvegicus
Awad, A.B.; Chattopadhyay, J.P.
Effect of dietary saturated fatty acids on intracellular free fatty acids and kinetic properties of hormone-sensitive lipase of rat adipocytes
J. Nutr.
116
1095-1100
1986
Rattus norvegicus
Holm, C.; Belfrage, P.; Osterlund, T.; Davis, R.C.; Schotz, M.C.; Langin, D.
Hormone-sensitive lipase: structure, function, evolution and overproduction in insect cells using the baculovirus expression system
Protein Eng.
7
537-541
1994
Rattus norvegicus
Wang, J.; Shen, W.J.; Patel, S.; Harada, K.; Kraemer, F.B.
Mutational analysis of the "regulatory module" of hormone-sensitive lipase
Biochemistry
44
1953-1959
2005
Rattus norvegicus
Chahinian, H.; Ali, Y.B.; Abousalham, A.; Petry, S.; Mandrich, L.; Manco, G.; Canaan, S.; Sarda, L.
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases
Biochim. Biophys. Acta
1738
29-36
2005
Homo sapiens
De Jong, J.C.; Sorensen, L.G.; Tornqvist, H.; Jacobsen, P.
Carbazates as potent inhibitors of hormone-sensitive lipase
Bioorg. Med. Chem. Lett.
14
1741-1744
2004
Homo sapiens
O'Neill, M.; Watt, M.J.; Heigenhauser, G.J.; Spriet, L.L.
Effects of reduced free fatty acid availability on hormone-sensitive lipase activity in human skeletal muscle during aerobic exercise
J. Appl. Physiol.
97
1938-1945
2004
Homo sapiens
Lindvall, H.; Nevsten, P.; Stroem, K.; Wallenberg, R.; Sundler, F.; Langin, D.; Soerhede Winzell, M.; Holm, C.
A novel hormone-sensitive lipase isoform expressed in pancreatic beta-cells
J. Biol. Chem.
279
3828-3836
2004
Rattus norvegicus (Q6T861)
Deb, C.; Daniel, J.; Sirakova, T.D.; Abomoelak, B.; Dubey, V.S.; Kolattukudy, P.E.
A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis
J. Biol. Chem.
281
3866-3875
2006
Mycobacterium tuberculosis
Martin-Hidalgo, A.; Huerta, L.; Alvarez, N.; Alegria, G.; Del Val Toledo, M.; Herrera, E.
Expression, activity, and localization of hormone-sensitive lipase in rat mammary gland during pregnancy and lactation
J. Lipid Res.
46
658-668
2005
Rattus norvegicus
Ben Ali, Y.; Carriere, F.; Verger, R.; Petry, S.; Muller, G.; Abousalham, A.
Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases
J. Lipid Res.
46
994-1000
2005
Homo sapiens
Claus, T.H.; Lowe, D.B.; Liang, Y.; Salhanick, A.I.; Lubeski, C.K.; Yang, L.; Lemoine, L.; Zhu, J.; Clairmont, K.B.
Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose
J. Pharmacol. Exp. Ther.
315
1396-1402
2005
Homo sapiens
Roepstorff, C.; Vistisen, B.; Donsmark, M.; Nielsen, J.N.; Galbo, H.; Green, K.A.; Hardie, D.G.; Wojtaszewski, J.F.; Richter, E.A.; Kiens, B.
Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
J. Physiol.
560
551-562
2004
Homo sapiens
Kraemer, F.B.; Shen, W.J.; Harada, K.; Patel, S.; Osuga, J.I.; Ishibashi, S.; Azhar, S.
Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis
Mol. Endocrinol.
18
549-557
2004
Mus musculus
Donsmark, M.; Langfort, J.; Holm, C.; Ploug, T.; Galbo, H.
Regulation and role of hormone-sensitive lipase in rat skeletal muscle
Proc. Nutr. Soc.
63
309-314
2004
Rattus norvegicus
Watt, M.J.; Spriet, L.L.
Regulation and role of hormone-sensitive lipase activity in human skeletal muscle
Proc. Nutr. Soc.
63
315-322
2004
Homo sapiens
Roepstorff, C.; Donsmark, M.; Thiele, M.; Vistisen, B.; Stewart, G.; Vissing, K.; Schjerling, P.; Hardie, D.G.; Galbo, H.; Kiens, B.
Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
Am. J. Physiol. Endocrinol. Metab.
291
E1106-E1114
2006
Homo sapiens
Ryden, M.; Jocken, J.; van Harmelen, V.; Dicker, A.; Hoffstedt, J.; Wiren, M.; Blomqvist, L.; Mairal, A.; Langin, D.; Blaak, E.; Arner, P.
Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis
Am. J. Physiol. Endocrinol. Metab.
292
E1847-E1855
2007
Homo sapiens (Q05469), Homo sapiens
Mottillo, E.P.; Shen, X.J.; Granneman, J.G.
Role of hormone-sensitive lipase in beta-adrenergic remodeling of white adipose tissue
Am. J. Physiol. Endocrinol. Metab.
293
E1188-E1197
2007
Mus musculus (P54310)
Mandrich, L.; Pezzullo, M.; Rossi, M.; Manco, G.
SSoNDELTA and SSoNDELTAlong: two thermostable esterases from the same ORF in the archaeon Sulfolobus solfataricus?
Archaea
2
109-115
2007
Saccharolobus solfataricus (Q97VU2), Saccharolobus solfataricus
Aboulaich, N.; Ortegren, U.; Vener, A.V.; Stralfors, P.
Association and insulin regulated translocation of hormone-sensitive lipase with PTRF
Biochem. Biophys. Res. Commun.
350
657-661
2006
Homo sapiens
Palin, S.L.; McTernan, P.G.; McGee, K.C.; Sturdee, D.W.; Barnett, A.H.; Kumar, S.
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormone-sensitive lipase in human subcutaneous abdominal adipocytes
Diabetes Obes. Metab.
9
585-590
2007
Homo sapiens
Shen, W.J.; Liang, Y.; Wang, J.; Harada, K.; Patel, S.; Michie, S.A.; Osuga, J.; Ishibashi, S.; Kraemer, F.B.
Regulation of hormone-sensitive lipase in islets
Diabetes Res. Clin. Pract.
75
14-26
2007
Mus musculus
Helge, J.W.; Biba, T.O.; Galbo, H.; Gaster, M.; Donsmark, M.
Muscle triacylglycerol and hormone-sensitive lipase activity in untrained and trained human muscles
Eur. J. Appl. Physiol.
97
566-572
2006
Homo sapiens
Miyoshi, H.; Souza, S.C.; Zhang, H.H.; Strissel, K.J.; Christoffolete, M.A.; Kovsan, J.; Rudich, A.; Kraemer, F.B.; Bianco, A.C.; Obin, M.S.; Greenberg, A.S.
Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms
J. Biol. Chem.
281
15837-15844
2006
Mus musculus
Schweiger, M.; Schreiber, R.; Haemmerle, G.; Lass, A.; Fledelius, C.; Jacobsen, P.; Tornqvist, H.; Zechner, R.; Zimmermann, R.
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
J. Biol. Chem.
281
40236-40241
2006
Mus musculus
Smith, A.J.; Thompson, B.R.; Sanders, M.A.; Bernlohr, D.A.
Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: regulation by fatty acids and phosphorylation
J. Biol. Chem.
282
32424-32432
2007
Homo sapiens
Ueno, M.; Suzuki, J.; Zenimaru, Y.; Takahashi, S.; Koizumi, T.; Noriki, S.; Yamaguchi, O.; Otsu, K.; Shen, W.J.; Kraemer, F.B.; Miyamori, I.
Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice
Am. J. Physiol. Endocrinol. Metab.
294
E1109-E1118
2008
Mus musculus, Mus musculus C57BL/6
Fernandez, C.; Hansson, O.; Nevsten, P.; Holm, C.; Klint, C.
Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise
Am. J. Physiol. Endocrinol. Metab.
295
E179-E186
2008
Homo sapiens (Q05469)
Tazoe, F.; Yagyu, H.; Okazaki, H.; Igarashi, M.; Eto, K.; Nagashima, S.; Inaba, T.; Shimano, H.; Osuga, J.; Ishibashi, S.
Induction of ABCA1 by overexpression of hormone-sensitive lipase in macrophages
Biochem. Biophys. Res. Commun.
376
111-115
2008
Mus musculus
Yonezawa, T.; Haga, S.; Kobayashi, Y.; Katoh, K.; Obara, Y.
Regulation of hormone-sensitive lipase expression by saturated fatty acids and hormones in bovine mammary epithelial cells
Biochem. Biophys. Res. Commun.
376
36-39
2008
Bos taurus (P16386), Bos taurus
Larsson, S.; Wierup, N.; Sundler, F.; Eliasson, L.; Holm, C.
Lack of cholesterol mobilization in islets of hormone-sensitive lipase deficient mice impairs insulin secretion
Biochem. Biophys. Res. Commun.
376
558-562
2008
Mus musculus
Nam, K.H.; Kim, M.Y.; Kim, S.J.; Priyadarshi, A.; Lee, W.H.; Hwang, K.Y.
Structural and functional analysis of a novel EstE5 belonging to the subfamily of hormone-sensitive lipase
Biochem. Biophys. Res. Commun.
379
553-556
2009
uncultured bacterium (Q0GMU2)
Jocken, J.W.; Roepstorff, C.; Goossens, G.H.; van der Baan, P.; van Baak, M.; Saris, W.H.; Kiens, B.; Blaak, E.E.
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation
Diabetes
57
1834-1841
2008
Homo sapiens
Fex, M.; Haemmerle, G.; Wierup, N.; Dekker-Nitert, M.; Rehn, M.; Ristow, M.; Zechner, R.; Sundler, F.; Holm, C.; Eliasson, L.; Mulder, H.
A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis
Diabetologia
52
271-280
2009
Mus musculus (P54310), Mus musculus
Lobo, M.V.; Huerta, L.; Arenas, M.I.; Busto, R.; Lasuncion, M.A.; Martin-Hidalgo, A.
Hormone-sensitive lipase expression and IHC localization in the rat ovary, oviduct, and uterus
J. Histochem. Cytochem.
57
51-60
2009
Rattus norvegicus (P15304)
Sekiya, M.; Osuga, J.; Yahagi, N.; Okazaki, H.; Tamura, Y.; Igarashi, M.; Takase, S.; Harada, K.; Okazaki, S.; Iizuka, Y.; Ohashi, K.; Yagyu, H.; Okazaki, M.; Gotoda, T.; Nagai, R.; Kadowaki, T.; Shimano, H.; Yamada, N.; Ishibashi, S.
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
J. Lipid Res.
49
1829-1838
2008
Mus musculus
Krintel, C.; Osmark, P.; Larsen, M.R.; Resjoe, S.; Logan, D.T.; Holm, C.
Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
PLoS ONE
3
e3756
2008
Homo sapiens (Q05469), Homo sapiens
Minkkilä, A.; Savinainen, J.; Käsnänen, H.; Xhaard, H.; Nevalainen, T.; Laitinen, J.; Poso, A.; Leppänen, J.; Saario, S.
Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors
ChemMedChem
4
1253-1259
2009
Homo sapiens
Lampidonis, A.D.; Argyrokastritis, A.; Stravopodis, D.J.; Voutsinas, G.E.; Ntouroupi, T.G.; Margaritis, L.H.; Bizelis, I.; Rogdakis, E.
Cloning and functional characterization of the ovine Hormone Sensitive Lipase (HSL) full-length cDNAs: an integrated approach
Gene
416
30-43
2008
Ovis aries, Ovis aries (B3EYB8), Ovis aries (B3EYB9)
Soror, S.H.; Rao, R.; Cullum, J.
Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces coelicolor A3 (2)
Protein Eng. Des. Sel.
22
333-339
2009
Streptomyces coelicolor
Langfort, J.; Jagsz, S.; Dobrzyn, P.; Brzezinska, Z.; Klapcinska, B.; Galbo, H.; Gorski, J.
Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle
Biochem. Biophys. Res. Commun.
399
670-676
2010
Rattus norvegicus
Ogasawara, J.; Nomura, S.; Rahman, N.; Sakurai, T.; Kizaki, T.; Izawa, T.; Ishida, H.; Haga, S.; Ohno, H.
Hormone-sensitive lipase is critical mediators of acute exercise-induced regulation of lipolysis in rat adipocytes
Biochem. Biophys. Res. Commun.
400
134-139
2010
Rattus norvegicus, Rattus norvegicus Wistar
Rodriguez, J.; Ben Ali, Y.; Abdelkafi, S.; Mendoza, L.; Leclaire, J.; Fotiadu, F.; Buono, G.; Carrière, F.; Abousalham, A.
In vitro stereoselective hydrolysis of diacylglycerols by hormone-sensitive lipase
Biochim. Biophys. Acta
1801
77-83
2010
Homo sapiens
Shen, W.J.; Yu, Z.; Patel, S.; Jue, D.; Liu, L.F.; Kraemer, F.B.
Hormone-sensitive lipase modulates adipose metabolism through PPARgamma
Biochim. Biophys. Acta
1811
9-16
2011
Mus musculus, Mus musculus C57/BL6J
Kittilson, J.D.; Reindl, K.M.; Sheridan, M.A.
Rainbow trout (Oncorhynchus mykiss) possess two hormone-sensitive lipase-encoding mRNAs that are differentially expressed and independently regulated by nutritional state
Comp. Biochem. Physiol. A
158
52-60
2011
Oncorhynchus mykiss (E2JFF5), Oncorhynchus mykiss (E2JFF6), Oncorhynchus mykiss
Kawasaki, M.; Miura, Y.; Yagasaki, K.
Effects of sulfur amino acids, L-methionine, L-cystine and L-cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes
Cytotechnology
62
225-233
2010
Mus musculus
Pinent, M.; Prokesch, A.; Hackl, H.; Voshol, P.J.; Klatzer, A.; Walenta, E.; Panzenboeck, U.; Kenner, L.; Trajanoski, Z.; Hoefler, G.; Bogner-Strauss, J.G.
Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice
Endocrinology
152
2678-2689
2011
Mus musculus
Ngo, T.D.; Ryu, B.H.; Ju, H.; Jang, E.; Park, K.; Kim, K.K.; Kim, T.D.
Structural and functional analyses of a bacterial homologue of hormone-sensitive lipase from a metagenomic library
Acta Crystallogr. Sect. D
69
1726-1737
2013
uncultured bacterium (Q4TZQ3)
Ascione, G.; de Pascale, D.; De Santi, C.; Pedone, C.; Dathan, N.A.; Monti, S.M.
Native expression and purification of hormone-sensitive lipase from Psychrobacter sp. TA144 enhances protein stability and activity
Biochem. Biophys. Res. Commun.
420
542-546
2012
Psychrobacter sp., Psychrobacter sp. TA144
De Santi, C.; Durante, L.; Vecchio, P.D.; Tutino, M.L.; Parrilli, E.; de Pascale, D.
Thermal stabilization of psychrophilic enzymes: a case study of the cold-active hormone-sensitive lipase from Psychrobacter sp. TA144
Biotechnol. Prog.
28
946-952
2012
Psychrobacter sp., Psychrobacter sp. TA144
Wang, S.P.; Wu, J.W.; Bourdages, H.; Lefebvre, J.F.; Casavant, S.; Leavitt, B.R.; Labuda, D.; Trasler, J.; Smith, C.E.; Hermo, L.; Mitchell, G.A.
The catalytic function of hormone-sensitive lipase is essential for fertility in male mice
Endocrinology
155
3047-3053
2014
Mus musculus
Eichmann, T.O.; Kumari, M.; Haas, J.T.; Farese, R.V.; Zimmermann, R.; Lass, A.; Zechner, R.
Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases
J. Biol. Chem.
287
41446-41457
2012
Mus musculus, Mus musculus C57BL/6
Manna, P.R.; Cohen-Tannoudji, J.; Counis, R.; Garner, C.W.; Huhtaniemi, I.; Kraemer, F.B.; Stocco, D.M.
Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein
J. Biol. Chem.
288
8505-8518
2013
Mus musculus, Mus musculus MA-10
Tanigawa, K.; Degang, Y.; Kawashima, A.; Akama, T.; Yoshihara, A.; Ishido, Y.; Makino, M.; Ishii, N.; Suzuki, K.
Essential role of hormone-sensitive lipase (HSL) in the maintenance of lipid storage in Mycobacterium leprae-infected macrophages
Microb. Pathog.
52
285-291
2012
Homo sapiens
Marvyn, P.M.; Bradley, R.M.; Button, E.B.; Mardian, E.B.; Duncan, R.E.
Fasting upregulates adipose triglyceride lipase and hormone-sensitive lipase levels and phosphorylation in mouse kidney
Biochem. Cell Biol.
93
262-267
2015
Mus musculus
Vasilieva, E.; Dutta, S.; Malla, R.K.; Martin, B.P.; Spilling, C.D.; Dupureur, C.M.
Rat hormone sensitive lipase inhibition by cyclipostins and their analogs
Bioorg. Med. Chem.
23
944-952
2015
Rattus norvegicus
Ogiyama, T.; Yamaguchi, M.; Kurikawa, N.; Honzumi, S.; Yamamoto, Y.; Sugiyama, D.; Takakusa, H.; Inoue, S.I.
Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation
Bioorg. Med. Chem.
25
2234-2243
2017
Homo sapiens
Ogiyama, T.; Yamaguchi, M.; Kurikawa, N.; Honzumi, S.; Terayama, K.; Nagaoka, N.; Yamamoto, Y.; Kimura, T.; Sugiyama, D.; Inoue, S.I.
Design, synthesis, and pharmacological evaluation of a novel series of hormone sensitive lipase inhibitor
Bioorg. Med. Chem.
25
4817-4828
2017
Homo sapiens
Dukunde, A.; Schneider, D.; Lu, M.; Brady, S.; Daniel, R.
A novel, versatile family IV carboxylesterase exhibits high stability and activity in a broad pH spectrum
Biotechnol. Lett.
39
577-587
2017
uncultured organism (G3CRD1)
Choi, Y.H.; Lee, Y.N.; Park, Y.J.; Yoon, S.J.; Lee, H.B.
Identification of amino acids related to catalytic function of Sulfolobus solfataricus P1 carboxylesterase by site-directed mutagenesis and molecular modeling
BMB Rep.
49
349-354
2016
Saccharolobus solfataricus (A0A0E3GVY6), Saccharolobus solfataricus P1 (A0A0E3GVY6), Saccharolobus solfataricus DSM1616 (A0A0E3GVY6)
Dua, A.; Gupta, R.
Functional characterization of hormone sensitive-like lipase from Bacillus halodurans synthesis and recovery of pNP-laurate with high yields
Extremophiles
21
871-889
2017
Halalkalibacterium halodurans (Q9KAN9), Halalkalibacterium halodurans DSM 18197 (Q9KAN9)
Sun, J.; Yang, Z.; Xiao, P.; Liu, Y.; Ji, H.; Du, Z.; Chen, L.
Two isoforms of hormone-sensitive lipase b are generated by alternative exons usage and transcriptional regulation by insulin in grass carp (Ctenopharyngodon idella)
Fish Physiol. Biochem.
43
539-547
2017
Ctenopharyngodon idella
Takanashi, M.; Taira, Y.; Okazaki, S.; Takase, S.; Kimura, T.; Li, C.C.; Xu, P.F.; Noda, A.; Sakata, I.; Kumagai, H.; Ikeda, Y.; Iizuka, Y.; Yahagi, N.; Shimano, H.; Osuga, J.I.; Ishibashi, S.; Kadowaki, T.; Okazaki, H.
Role of hormone-sensitive lipase in leptin-promoted fat loss and glucose lowering
J. Artheroscler. Thromb.
24
110-1116
2017
Mus musculus (P54310)
Whytock, K.L.; Shepherd, S.O.; Wagenmakers, A.J.M.; Strauss, J.A.
Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise
J. Physiol.
596
2077-2090
2018
Homo sapiens (Q05469), Homo sapiens
Sommer, B.; Overy, D.P.; Haltli, B.; Kerr, R.G.
Secreted lipases from Malassezia globosa recombinant expression and determination of their substrate specificities
Microbiology
162
1069-1079
2016
Malassezia globosa (A8PUY1), Malassezia globosa (A8PUY5), Malassezia globosa (A8QCW4), Malassezia globosa (A8QDF0), Malassezia globosa, Malassezia globosa CBS 7966 (A8PUY1), Malassezia globosa CBS 7966 (A8PUY5), Malassezia globosa CBS 7966 (A8QCW4), Malassezia globosa CBS 7966 (A8QDF0), Malassezia globosa ATCC MYA-4612 (A8PUY1), Malassezia globosa ATCC MYA-4612 (A8PUY5), Malassezia globosa ATCC MYA-4612 (A8QCW4), Malassezia globosa ATCC MYA-4612 (A8QDF0)
Sanchez-Carbente, M.D.R.; Batista-Garcia, R.A.; Sanchez-Reyes, A.; Escudero-Garcia, A.; Morales-Herrera, C.; Cuervo-Soto, L.I.; French-Pacheco, L.; Fernandez-Silva, A.; Amero, C.; Castillo, E.; Folch-Mallol, J.L.
The first description of a hormone-sensitive lipase from a basidiomycete Structural insights and biochemical characterization revealed Bjerkandera adusta BaEstB as a novel esterase
MicrobiologyOpen
6
e463
2017
Bjerkandera adusta (A0A1S5T4Z0), Bjerkandera adusta
Huang, J.; Huo, Y.; Ji, R.; Kuang, S.; Ji, C.; Xu, X.; Li, J.
Structural insights of a hormone sensitive lipase homologue Est22
Sci. Rep.
6
28550
2016
uncultured bacterium (H6BDX1)
html completed
