Reference on EC 3.1.1.7 - acetylcholinesterase and Organism(s) Mus musculus and UniProt Accession P21836
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bourne, Y.; Taylor, P.; Bougis, P.E.; Marchot, P.
Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly
J. Biol. Chem.
274
2963-2970
1999
Mus musculus
Marchot, P.; Ravelli, R.B.G.; Raves, M.L.; Bourne, Y.; Vellom, D.C.; Kanter, J.; Camp, S.; Sussman, J.L.; Taylor, P.
Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin
Protein Sci.
5
672-679
1996
Mus musculus
Gomez, J.L.; Moral-Naranjo, M.T.; Compoy, F.J.; Vidal, C.J.
Characterization of acetylcholinesterase and butyrylcholinesterase forms in normal and dystrophic Lama2dy mouse heart
J. Neurosci. Res.
56
295-306
1999
Mus musculus
Kovarik, Z.; Radic, Z.; Berman, H.A.; Simeon-Rudolf, V.; Reiner, E.; Taylor, P.
Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates
Biochem. J.
373
33-40
2003
Mus musculus (P21836), Mus musculus
Kovarik, Z.; Radic, Z.; Berman, H.A.; Simeon-Rudolf, V.; Reiner, E.; Taylor, P.
Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates
Biochemistry
43
3222-3229
2004
Mus musculus
Zatta, P.; Ibn-Lkhayat-Idrissi, M.; Zambenedetti, P.; Kilyen, M.; Kiss, T.
In vivo and in vitro effects of aluminum on the activity of mouse brain acetylcholinesterase
Brain Res. Bull.
59
41-45
2002
Mus musculus
Saxena, A.; Fedorko, J.M.; Vinayaka, C.R.; Medhekar, R.; Radic, Z.; Taylor, P.; Lockridge, O.; Doctor, B.P.
Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases
Eur. J. Biochem.
270
4447-4458
2003
Mus musculus, Tetronarce californica
Gomez, J.L.; Nieto-Ceron, S.; Campoy, F.J.; Munoz-Delgado, E.; Vidal, C.J.
Purification and properties of hydrophilic dimers of acetylcholinesterase from mouse erythrocytes
Int. J. Biochem. Cell Biol.
35
1109-1118
2003
Mus musculus
Kua, J.; Zhang, Y.; McCammon, J.A.
Studying enzyme binding specificity in acetylcholinesterase using a combined molecular dynamics and multiple docking approach
J. Am. Chem. Soc.
124
8260-8267
2002
Mus musculus
Boyd, A.E.; Marnett, A.B.; Wong, L.; Taylor, P.
Probing the active center gorge of acetylcholinesterase by fluorophores linked to substituted cysteines
J. Biol. Chem.
275
22401-22408
2000
Mus musculus
Shi, J.; Boyd, A.E.; Radic, Z.; Taylor, P.
Reversibly bound and covalently attached ligands induce conformational changes in the omega loop, Cys69-Cys96, of mouse acetylcholinesterase
J. Biol. Chem.
276
42196-42204
2001
Mus musculus
Shi, J.; Tai, K.; McCammon, J.A.; Taylor, P.; Johnson, D.A.
Nanosecond dynamics of the mouse acetylcholinesterase Cys69-Cys96 omega loop
J. Biol. Chem.
278
30905-30911
2003
Mus musculus (P21836), Mus musculus
Kardos, S.A.; Sultatos, L.G.
Interactions of the organophosphates paraoxon and methyl paraoxon with mouse brain acetylcholinesterase
Toxicol. Sci.
58
118-126
2000
Mus musculus
Kovarik, Z.; Ciban, N.; Radic, Z.; Simeon-Rudolf, V.; Taylor, P.
Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP
Biochem. Biophys. Res. Commun.
342
973-978
2006
Mus musculus
Ekstrom, F.; Akfur, C.; Tunemalm, A.K.; Lundberg, S.
Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase
Biochemistry
45
74-81
2006
Mus musculus (P21836), Mus musculus
Kim, H.K.; Kim, M.; Kim, S.; Kim, M; Chung, J.H.
Effects of green tea polyphenol on cognitive and acetylcholinesterase activities
Biosci. Biotechnol. Biochem.
68
1977-1979
2004
Mus musculus
Cometa, M.F.; Lorenzini, P.; Fortuna, S.; Volpe, M.T.; Meneguz, A.; Palmery, M.
In vitro inhibitory effect of aflatoxin B1 on acetylcholinesterase activity in mouse brain
Toxicology
206
125-135
2005
Mus musculus
Hoernberg, A.; Tunemalm, A.K.; Ekstroem, F.
Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state
Biochemistry
46
4815-4825
2007
Mus musculus (P21836), Mus musculus
Bourne, Y.; Radic, Z.; Sulzenbacher, G.; Kim, E.; Taylor, P.; Marchot, P.
Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding
J. Biol. Chem.
281
29256-29267
2006
Mus musculus (P21836), Mus musculus
Ko, S.O.; Kim, T.H.; Lee, H.K.; Lee, J.C.; Cho, E.S.
Temporospatial localization of acetylcholinesterase activity in the dental epithelium during mouse tooth development
Life Sci.
81
1235-1240
2007
Mus musculus
Taylor, P.; Kovarik, Z.; Reiner, E.; Radic, Z.
Acetylcholinesterase: converting a vulnerable target to a template for antidotes and detection of inhibitor exposure
Toxicology
233
70-78
2007
Mus musculus
Bosak, A.; Gazic, I.; Vinkovic, V.; Kovarik, Z.
Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol
Arch. Biochem. Biophys.
471
72-76
2008
Mus musculus (P21836), Mus musculus
Agrawal, R.; Tyagi, E.; Shukla, R.; Nath, C.
Effect of insulin and melatonin on acetylcholinesterase activity in the brain of amnesic mice
Behav. Brain Res.
189
381-386
2008
Mus musculus
Papandreou, M.A.; Dimakopoulou, A.; Linardaki, Z.I.; Cordopatis, P.; Klimis-Zacas, D.; Margarity, M.; Lamari, F.N.
Effect of a polyphenol-rich wild blueberry extract on cognitive performance of mice, brain antioxidant markers and acetylcholinesterase activity
Behav. Brain Res.
198
352-358
2009
Mus musculus
Pavlov, V.A.; Parrish, W.R.; Rosas-Ballina, M.; Ochani, M.; Puerta, M.; Ochani, K.; Chavan, S.; Al-Abed, Y.; Tracey, K.J.
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway
Brain Behav. Immun.
23
41-45
2009
Mus musculus
Vignaud, A.; Fougerousse, F.; Mouisel, E.; Guerchet, N.; Hourde, C.; Bacou, F.; Butler-Browne, G.S.; Chatonnet, A.; Ferry, A.
Genetic inactivation of acetylcholinesterase causes functional and structural impairment of mouse soleus muscles
Cell Tissue Res.
333
289-296
2008
Mus musculus
Cheng, Y.H.; Cheng, X.L.; Radi?, Z.; McCammon, J.A.
Acetylcholinesterase: mechanisms of covalent inhibition of H447I mutant determined by computational analyses
Chem. Biol. Interact.
175
196-199
2008
Mus musculus (P21836), Mus musculus
Jazi, R.; Lalonde, R.; Qian, S.; Strazielle, C.
Regional brain evaluation of acetylcholinesterase activity in PS1/A246E transgenic mice
Neurosci. Res.
63
106-114
2009
Mus musculus
Hoernberg, A.; Artursson, E.; Waerme, R.; Pang, Y.P.; Ekstroem, F.
Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad
Biochem. Pharmacol.
79
507-515
2010
Mus musculus (P21836), Mus musculus
Guo, L.; Suarez, A.I.; Braden, M.R.; Gerdes, J.M.; Thompson, C.M.
Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates
Bioorg. Med. Chem. Lett.
20
1194-1197
2010
Electrophorus electricus, Mus musculus
Bhattacharjee, A.K.; Kuca, K.; Musilek, K.; Gordon, R.K.
In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties
Chem. Res. Toxicol.
23
26-36
2010
Mus musculus
Kakinuma, Y.; Furihata, M.; Akiyama, T.; Arikawa, M.; Handa, T.; Katare, R.G.; Sato, T.
Donepezil, an acetylcholinesterase inhibitor against Alzheimers dementia, promotes angiogenesis in an ischemic hindlimb model
J. Mol. Cell. Cardiol.
48
680-693
2010
Homo sapiens, Mus musculus
Lee, Y.K.; Yuk, D.Y.; Kim, T.I.; Kim, Y.H.; Kim, K.T.; Kim, K.H.; Lee, B.J.; Nam, S.Y.; Hong, J.T.
Protective effect of the ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on scopolamine-induced memory impairment and the inhibition of acetylcholinesterase activity
J. Nat. Med.
63
274-282
2009
Mus musculus
Artursson, E.; Andersson, P.O.; Akfur, C.; Linusson, A.; Boerjegren, S.; Ekstroem, F.
Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: possible implications for the HI-6 antidote substrate specificity
Biochem. Pharmacol.
85
1389-1397
2013
Homo sapiens, Mus musculus (P21836), Mus musculus
