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Disease on EC 3.1.1.67 - fatty-acyl-ethyl-ester synthase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinogenesis
Chronic alcohol drinking: Liver and pancreatic cancer?
Metabolism of ethanol and carcinogens by glutathione transferases.
Carcinoma, Hepatocellular
Differential inhibition of hepatic, pancreatic, and plasma fatty acid ethyl ester synthase by tri-o-tolylphosphate in rats.
Mechanism of differential inhibition of hepatic and pancreatic fatty acid ethyl ester synthase by inhibitors of serine-esterases: in vitro and cell culture studies.
Cardiomyopathies
Mutagenesis and characterization of specific residues in fatty acid ethyl ester synthase: a gene for alcohol-induced cardiomyopathy.
Cardiotoxicity
Rapid fatty acid ethyl ester synthesis by porcine myocardium upon ethanol infusion into the left anterior descending coronary artery.
Fetal Growth Retardation
Association of Fatty Acid Ethyl Esters in Meconium of Neonates with Growth Deficits at Birth: a Prospective, Single-Centre Cohort Study.
Glioma
Nonoxidative ethanol metabolism: expression of fatty acid ethyl ester synthase-III in cultured neural cells.
Hepatoblastoma
The synthesis and secretion of fatty acid ethyl esters from HepG2 cells are stimulated by lipoproteins and albumin.
Hyperlipidemias
?-3 Fatty Acid Ethyl Esters Diminish Postprandial Lipemia in Familial Hypercholesterolemia.
Hypertriglyceridemia
In heavy drinkers fatty acid ethyl esters in the serum are increased for 44 hr after ethanol consumption.
Lung Diseases
Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding.
Neoplasms
Alcohol oxidizing enzymes and ethanol-induced cytotoxicity in rat pancreatic acinar AR42J cells.
Ethanol-induced cytotoxicity in rat pancreatic acinar AR42J cells: role of fatty acid ethyl esters.
Mechanism of differential inhibition of hepatic and pancreatic fatty acid ethyl ester synthase by inhibitors of serine-esterases: in vitro and cell culture studies.
Neuroblastoma
Nonoxidative ethanol metabolism: expression of fatty acid ethyl ester synthase-III in cultured neural cells.
Obesity
Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men.
Pancreatic Diseases
Fatty acid ethyl ester synthase, an enzyme for nonoxidative ethanol metabolism, is present in serum after liver and pancreatic injury.
Pancreatic Neoplasms
Chronic alcohol drinking: Liver and pancreatic cancer?
Pancreatitis
Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis.
Fatty acid ethyl esters and ethanol-induced pancreatitis.
Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol.
Pathophysiology and Biomarker Potential of Fatty Acid Ethyl Ester Elevation During Alcoholic Pancreatitis.
Pancreatitis, Acute Necrotizing
Fatty Acid Ethyl Esters Are Less Toxic Than Their Parent Fatty Acids Generated during Acute Pancreatitis.
Pancreatitis, Alcoholic
Pancreatic cholesterol esterase, ES-10, and fatty acid ethyl ester synthase III gene expression are increased in the pancreas and liver but not in the brain or heart with long-term ethanol feeding in rats.
Pathophysiology and Biomarker Potential of Fatty Acid Ethyl Ester Elevation During Alcoholic Pancreatitis.
Pneumonia
Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism.