show all | hide all No of entries

Information on EC 3.1.1.57 - 2-pyrone-4,6-dicarboxylate lactonase

for references in articles please use BRENDA:EC3.1.1.57
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase
IUBMB Comments
The product is most likely the keto-form of 4-oxalomesaconate (as shown in the reaction) [1,2]. It can be converted to the enol-form, 4-hydroxybuta-1,3-diene-1,2,4-trioate, either spontaneously or by EC 5.3.2.8, 4-oxalomesaconate tautomerase .
Specify your search results
Select one or more organisms in this record: ?
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
2-pyrone-4,6-dicarboxylate hydrolase, 2-pyrone-4,6-dicarboxylate lactonase, pdc hydrolase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-oxo-2H-pyran-4,6-dicarboxylate + H2O = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate
show the reaction diagram
the product isomerizes to 4-oxalmesaconate
-
-
0
Select items on the left to see more content.