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Information on EC 3.1.1.26 - galactolipase
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3.1.1.26 galactolipaseIUBMB Comments
Also acts on 2,3-di-O-acyl-1-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-D-glycerol, and phosphatidylcholine and other phospholipids.
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Word Map
- 3.1.1.26
- fabry
- galactose
-
senescence-associated
-
x-linked
- galactolipids
-
lipolytic
- lipases
-
fucosidase
- glycosphingolipids
- globotriaosylceramide
- patatins
- angiokeratomas
-
glucuronidase
- colipase
-
mannosidase
-
exoglycosidase
- anderson-fabry
- monogalactosyldiacylglycerol
- digalactosyldiacylglycerol
-
acroparesthesias
-
patatin-like
- xylosidase
- synthesis
The enzyme appears in viruses and cellular organisms
Synonyms
galactosidase, galactolipase, plrp1, dongle, lipid acyl hydrolase, pancreatic lipase-related protein 1, vupat1, lipid acyl-hydrolase, galactolipid acyl hydrolase, glycerolipid acyl-hydrolase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
chGL
ckGL
DGL
-
shows strong galactolipase and weak phospholipase A1 activities and plays a role in the early phase of jasmonic acid production
FSL
galactolipase
glp1
LAH
lipid acyl hydrolase
NECHADRAFT_49364
pancreatic lipase-related protein 1
pancreatic lipase-related protein 2
PLRP1
PLRP2
Talaromyces thermophilus lipase
TTL
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates
also acts on 2,3-di-O-acyl-1-O-(6-O-alpha-D-galactosyl)-D-glycerol, and phosphatidylcholine and other phospholipids
-
-
-
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase
Also acts on 2,3-di-O-acyl-1-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-D-glycerol, and phosphatidylcholine and other phospholipids.
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CAS REGISTRY NUMBER
COMMENTARY
37278-40-3
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,2-di-O-alpha-eleostearoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
? + alpha-eleostearic acid
best substrate
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
1,2-diacyl-3-(6-O-alpha-D-Gal-beta-D-Gal)glycerol + H2O
2,3-dihydroxypropyl 6-O-alpha-D-galactopyranosyl-beta-D-galactopyranoside + 2 fatty acid
-
-
-
-
?
1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H2O
2-acyl-3-beta-D-galactosyl-sn-glycerol + fatty acid
-
-
-
?
1,2-diacyl-3-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-sn-glycerol + H2O
2-acyl-3-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-sn-glycerol + fatty acid
1,2-diacyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-acyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + fatty acid
-
-
-
?
1,2-didodecanoyl phosphatidylglycerol + 2 H2O
2 dodecanoate + sn-glycerol 3-phosphate
-
-
-
-
?
1,2-dimyristoyl-sn-glycero-3-phosphate + H2O
2-myristoyl-sn-glycero-3-phosphate + myristate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + octanoate
1,2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + octanoate
1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-)glycerol + H2O
2-oleoyl-sn-glycero-3-phospho-(1'-rac-)glycerol + palmitate
-
-
-
?
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine + H2O
2-oleoyl-sn-glycero-3-phosphocholine + palmitate
low activity
-
-
?
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
?
low activity
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + 2 H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-octanoyl-sn-glycerol + H2O
?
-
-
-
?
3-O-beta-D-galactopyranosyl-1,2-di-O-dodecanoyl-sn-glycerol + fatty acid + H2O
2,3-dihydroxypropyl-beta-D-galactopyranoside + dodecanoate
-
-
-
-
?
acylsterylglucoside + H2O
?
-
500% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosyldilinolenin + H2O
digalactosylglycerol + linolenic acid
-
-
-
-
?
monogalactosyl dioctanoylglycerol + H2O
galactosylglycerol + 2 octanoate
-
-
-
?
monogalactosyldilinolenin + H2O
monogalactosylglycerol + linolenic acid
-
-
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + fatty acid
-
-
-
-
?
phosphatidylinositol + H2O
?
-
36% of the activity with monogalactosyldiacylglycerol
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
galactolipase activity of LRP2
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
?
1,2-di-O-dodecanoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + H2O
2,3-dihydroxypropyl beta-D-galactopyranoside + dodecanoate
-
-
-
?
1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H2O
?
-
-
-
?
1,2-diacyl-3-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-sn-glycerol + H2O
2-acyl-3-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-sn-glycerol + fatty acid
-
-
-
-
?
1,2-diacyl-3-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-sn-glycerol + H2O
2-acyl-3-O-(6-O-alpha-D-galactosyl-beta-D-galactosyl)-sn-glycerol + fatty acid
-
-
-
-
?
1,2-diacyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
?
-
-
-
?
1,2-diacyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
?
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-(1->6)-beta-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
1,2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + H2O
2-octanoyl-3-O-alpha-D-galactosyl-sn-glycerol + octanoate
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
galactolipase activity of LRP2
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
?
3-O-(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)-1,2-di-O-dodecanoyl-sn-glycerol + H2O
2,3-dihydroxypropyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside + 2 dodecanoate
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
hydrolyzes both the saturated and unsaturated acyl groups
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
169% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
39% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
Pisum arvense
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
44% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
62% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
fatty acid with chain lengths of C16:0, C16:1, C18:1, C18:2, C18:3, the polyunsaturated substrates are preferentially hydrolyzed
-
-
?
digalactosyldiacylglycerol + H2O
digalactosylglycerol + fatty acid
-
-
-
-
?
digalactosylmonoacylglycerol + H2O
digalactosylglycerol + fatty acid
-
49% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosylmonoacylglycerol + H2O
digalactosylglycerol + fatty acid
-
146% of the activity with monogalactosyldiacylglycerol
-
-
?
digalactosylmonoacylglycerol + H2O
digalactosylglycerol + fatty acid
-
26% of the activity with monogalactosyldiacylglycerol
-
-
?