A group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
steryl-ester acylhydrolase
A group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts.
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
deletion of enzyme gene results in complete loss of plasma membrane steryl ester hydrolase activity, and an elevated level of zymosterol, overexpression results in significant elevation of activity
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
YLL012/YEH1, YLR020/YEH2, and TGL1 triple mutant is completely blocked in steryl ester hydrolysis. Overexpression of any of the three lipases is sufficient for steryl ester mobilization in vivo
Koeffel, R.; Tiwari, R.; Falquet, L.; Schneiter, R.
The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis