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Information on EC 3.1.1.101 - poly(ethylene terephthalate) hydrolase

for references in articles please use BRENDA:EC3.1.1.101
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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.101 poly(ethylene terephthalate) hydrolase
IUBMB Comments
The enzyme, isolated from the bacterium Ideonella sakaiensis, also produces small amounts of terephthalate (cf. EC 3.1.1.102, mono(ethylene terephthalate) hydrolase). The reaction takes place on PET-film placed in solution.
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This record set is specific for:
UNIPROT: W0TJ64
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
Synonyms
petase, tfcut2, poly(ethylene terephthalate) hydrolase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
PET hydrolase
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PETase
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SYSTEMATIC NAME
IUBMB Comments
poly(ethylene terephthalate) hydrolase
The enzyme, isolated from the bacterium Ideonella sakaiensis, also produces small amounts of terephthalate (cf. EC 3.1.1.102, mono(ethylene terephthalate) hydrolase). The reaction takes place on PET-film placed in solution.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
a search algorithm that allows the in silico identification of PET hydrolase gene candidates from genomes and metagenomes is developed. 504 novel possible enzyme candidates in the UniProtKB and nonredundant RefSeq databases and the metagenomic database available in the NCBI database are identified
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
W0TJ64_9PSEU
304
0
32969
TrEMBL
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Danso, D.; Schmeisser, C.; Chow, J.; Zimmermann, W.; Wei, R.; Leggewie, C.; Li, X.; Hazen, T.; Streit, W.R.
New insights into the function and global distribution of polyethylene terephthalate (PET)-degrading bacteria and enzymes in marine and terrestrial metagenomes
Appl. Environ. Microbiol.
84
e02773-17
2018
Ideonella sakaiensis (A0A0K8P6T7), Saccharomonospora viridis (W0TJ64), Thermobifida alba (E9LVH7), Thermobifida cellulosilytica (E9LVH9), Thermobifida fusca (E5BBQ3), Thermobifida fusca (E9LVI0), Thermobifida halotolerans (H6WX58), Thermomonospora curvata (D1A9G5), Thermomonospora curvata DSM 43183 (D1A9G5), uncultured bacterium (C3RYL0), uncultured bacterium (G9BY57)
Manually annotated by BRENDA team