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Information on EC 2.8.3.8 - acetate CoA-transferase and Organism(s) Roseburia hominis and UniProt Accession G2SYC0

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EC Tree
     2 Transferases
         2.8 Transferring sulfur-containing groups
             2.8.3 CoA-transferases
                2.8.3.8 acetate CoA-transferase
IUBMB Comments
The enzyme belongs to family I of CoA-transferases, which operate with a ping-pong kinetic mechanism. The reaction takes place in two half-reactions and involves the formation of a CoA thioester intermediate with a glutamate residue. Unlike EC 2.8.3.9, butyrate---acetoacetate CoA-transferase, this enzyme exhibits maximal activity using acetate as the CoA acceptor. Substrate range depends on the specific enzyme. Typical substrates include butanoyl-CoA and pentanoyl-CoA.
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This record set is specific for:
Roseburia hominis
UNIPROT: G2SYC0
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Word Map
The taxonomic range for the selected organisms is: Roseburia hominis
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
butyryl-coa:acetate coa-transferase, butyryl-coa acetate coa-transferase, acetate:succinate coa-transferase, butyryl-coenzyme a coa transferase, acetate coa-transferase, acyl-coa:acetate coa-transferase, acetoacetate:acetate coa-transferase, succinyl-coa:acetate coa transferase, butyryl coa:acetate coa transferase, butyryl coenzyme a transferase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
butyryl-coenzyme A CoA transferase
Q2TME9
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acetate coenzyme A-transferase
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butyryl CoA:acetate CoA transferase
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butyryl coenzyme A transferase
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coenzyme A-transferase, acetate
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succinyl-CoA:acetate CoA transferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
coenzyme A transfer
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SYSTEMATIC NAME
IUBMB Comments
acyl-CoA:acetate CoA-transferase
The enzyme belongs to family I of CoA-transferases, which operate with a ping-pong kinetic mechanism. The reaction takes place in two half-reactions and involves the formation of a CoA thioester intermediate with a glutamate residue. Unlike EC 2.8.3.9, butyrate---acetoacetate CoA-transferase, this enzyme exhibits maximal activity using acetate as the CoA acceptor. Substrate range depends on the specific enzyme. Typical substrates include butanoyl-CoA and pentanoyl-CoA.
CAS REGISTRY NUMBER
COMMENTARY hide
37278-35-6
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
molecular biology
Q2TME9
a new degenerated real-time PCR approach to simultaneously quantify phylogenetically different butyrate-producing bacteria based on the detection of butyryl-coenzyme A (CoA) CoA transferase genes is described
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Louis, P.; Flint, H.J.
Development of a semiquantitative degenerate real-time PCR-based assay for estimation of numbers of butyryl-coenzyme A (CoA) CoA transferase genes in complex bacterial samples
Appl. Environ. Microbiol.
73
2009-2012
2007
Anaerostipes caccae (Q2QB27), Faecalibacterium prausnitzii (Q2QIH0), Anaerobutyricum hallii (Q2QIH1), Roseburia hominis (Q2TME9), Roseburia hominis A2-183 (Q2TME9)
Manually annotated by BRENDA team