Information on EC 2.8.3.3 - malonate CoA-transferase

for references in articles please use BRENDA:EC2.8.3.3
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The expected taxonomic range for this enzyme is: Pseudomonas

EC NUMBER
COMMENTARY hide
2.8.3.3
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RECOMMENDED NAME
GeneOntology No.
malonate CoA-transferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + malonate = acetate + malonyl-CoA
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
coenzyme A transfer
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-
-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
acetyl CoA biosynthesis
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beta-Alanine metabolism
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SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:malonate CoA-transferase
The enzyme from Pseudomonas ovalis also catalyses the reaction of EC 4.1.1.9 malonyl-CoA decarboxylase.
CAS REGISTRY NUMBER
COMMENTARY hide
9026-18-0
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
IAM 1177
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-
Manually annotated by BRENDA team
IAM 1177
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-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + malonate
acetate + malonyl-CoA
show the reaction diagram
butyryl-CoA + malonate
malonyl-CoA + butanoate
show the reaction diagram
-
-
-
-
?
malonyl-CoA + malonate
malonyl-CoA + malonate
show the reaction diagram
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exchange reaction
-
-
?
methylmalonyl-CoA + malonate
malonyl-CoA + methylmalonate
show the reaction diagram
-
-
-
-
?
propionyl-CoA + malonate
malonyl-CoA + propanoate
show the reaction diagram
-
-
-
-
?
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + malonate
acetate + malonyl-CoA
show the reaction diagram
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
assay at
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30000
-
1 * 70000 + 1 * 40000 + 2 * 30000, alphabeta1(beta2)2, SDS-PAGE
40000
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1 * 70000 + 1 * 40000 + 2 * 30000, alphabeta1(beta2)2, SDS-PAGE
70000
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1 * 70000 + 1 * 40000 + 2 * 30000, alphabeta1(beta2)2, SDS-PAGE
170000
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gel filtration
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
tetramer
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE