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Information on EC 2.8.3.27 - propanoyl-CoA:succinate CoA transferase

for references in articles please use BRENDA:EC2.8.3.27

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IUBMB Comments

The enzyme is most specific in Escherichia coli, where the preferred substrates are propanoyl-CoA and succinate. In other organisms, the enzyme uses acetyl-CoA at the same rate as propanoyl-CoA (cf. EC 2.8.3.18, succinyl-CoA:acetate CoA-transferase).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
propionate:succinate coa-transferase, propionyl coa:succinate coa transferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
propanoyl-CoA + succinate = propanoate + succinyl-CoA
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
(S)-lactate fermentation to propanoate, acetate and hydrogen, anaerobic energy metabolism (invertebrates, mitochondrial), conversion of succinate to propanoate, pyruvate fermentation to propanoate I
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