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Information on EC 2.8.3.15 - succinyl-CoA:(R)-benzylsuccinate CoA-transferase

for references in articles please use BRENDA:EC2.8.3.15

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IUBMB Comments

Involved in anaerobic catabolism of toluene and is a strictly toluene-induced enzyme that catalyses the reversible regio- and enantio-selective synthesis of (R)-2-benzylsuccinyl-CoA. The enzyme from Thauera aromatica is inactive when (R)-benzylsuccinate is replaced by (S)-benzylsuccinate.

The enzyme appears in viruses and cellular organisms

Synonyms
succinyl-coa:(r)-benzylsuccinate coa-transferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
succinyl-CoA + (R)-2-benzylsuccinate = succinate + (R)-2-benzylsuccinyl-CoA
show the reaction diagram
Highest Expressing Human Cell Lines
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