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Information on EC 2.8.3.15 - succinyl-CoA:(R)-benzylsuccinate CoA-transferase

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IUBMB Comments
Involved in anaerobic catabolism of toluene and is a strictly toluene-induced enzyme that catalyses the reversible regio- and enantio-selective synthesis of (R)-2-benzylsuccinyl-CoA. The enzyme from Thauera aromatica is inactive when (R)-benzylsuccinate is replaced by (S)-benzylsuccinate.
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The enzyme appears in viruses and cellular organisms
Synonyms
benzylsuccinate CoA-transferase, coenzyme A-transferase, benzylsuccinate, IaaL, phenylsuccinyl-CoA transferase, succinyl coenzyme A-benzylsuccinate coenzyme A transferase, succinyl-CoA:phenylsuccinate CoA-transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
succinyl-CoA + (R)-2-benzylsuccinate = succinate + (R)-2-benzylsuccinyl-CoA
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